HPV Vaccination for Cancer Prevention

HPV Vaccination for Cancer Prevention

February 27, 2020

Pamela C. Hull, Ph.D.Rural Healthcare Providers Symposium

Collaborators and Partners

Vanderbilt University Medical CenterDebra Friedman, MDStephen Deppen, PhDTatsuki Koyama, PhDLiping Du, PhDCaree McAfee, MA, CHESJaimie Shing, MAJessica Jones, MSKelsey Minix, MPHAlyssa RentuzaJuan Canedo, DHSc

Vanderbilt UniversityShelagh Mulvaney, PhD

Meharry-Vanderbilt-TSU

Cancer PartnershipMeharry Medical CollegeMaureen Sanderson, PhD

Tennessee State UniversityElizabeth Williams, PhD

Cumberland Pediatric FoundationLora Harnack, MSNJanet CatesChristine Stroebel, MPH

Community PartnersMVTCP Community Advisory Board HPV Cancer Free Tennessee CoalitionTN Department of HealthProgreso Community Center

Supported by NIH grant numbers: R01CA207401, U54CA163072, U54CA163066, U54CA163069,

3P30CA068485-18S3, UL1 RR024975, UL1 TR000445, and VU Trans-Institutional Programs

Infections cause some cancers

Hepatitis C virus

Hepatitis B virus

Helicobacter pylori

HPV (human papillomavirus)

Courtesy of Krystle Kuhs, PhD

Data from Viens et al. MMWR 2016. https://www.cdc.gov/cancer/hpv/statistics

70%

91%

91%

69%

63%

75% HPV causes a large burden of cancers, pre-cancers, and

genital warts

% Attributed to HPV

Epidemic of HPV Oropharyngeal Cancer

Oropharynx (Overall)

HPV-positive Oropharynx

HPV-negative Oropharynx

10

1

Rat

es p

er

10

0,0

00

Calendar Years

HPV

Tobacco & Alcohol

225% Increase

Chaturvedi et al, J Clin Onc, 2011Courtesy of Krystle Kuhs, PhD

Oropharynx

Gillison Vaccine 2012; headandneckcancerguide.org

1 new case of HPV-related cancerevery 20 minutes

Screening is only available for cervical cancer

6-12 months after 1st dose 2 & 6 months after 1st dose

Routine HPV vaccination recommended for both males and females at ages 11 – 12 years

*Late: 13-26 years

MMWR 2016;65(49) 1405-1408 http://dx.doi.org/10.15585/mmwr.mm6549a5

Human Papilloma Virus (HPV) Vaccination

70%

48%

59%

45%45%

31%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

1+ Dose All Doses

Urban Suburban Rural/Town

*

Healthy People 2020 Goal: 80% Series Completion

*

*

* Significantly lower than

Urban at p<0.05

Source: 2018 NIS-Teen Data

Tennessee, 2018

HPV Vaccination: Challenges

17% increase in HPV vaccination during well visits

2.5-fold increase in providers using evidence-based

“announcement” communication

Baseline Follow UpResults

30% Increase in Bundling HPV Vaccinewith Other Adolescent Vaccines

Available Materials: Co-brand with your logo

MagnetFront & Back of Clinic Flyer (space for logo)

SPANISH

Billboard

Request: get3shots.org

TN Dept of Health:

Video

Print ads

Social media

Bus wraps

Request: TIP.Quality@tn.gov

https://www.youtube.com/watch?v=PfgS31AfGvs

www.hpvcancerfree.orgRochelle.Roberts@tn.gov

https://tinyurl.com/smbhbo5Kristina.G.Bradford@tn.gov

immunizetn@gmail.com

Supplemental Slide for Q&A