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Genetics: Multiple Alleles. Biology 12. Joke of the day:. Multiple Alleles. Many genes have more than two alleles An individual does not have more than two alleles for each trait but different individuals can have different pairs of alleles when multiple alleles exist. - PowerPoint PPT Presentation
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Genetics: Multiple AllelesBiology 12
Joke of the day:
Multiple Alleles Many genes have
more than two alleles An individual does
not have more than two alleles for each trait but different individuals can have different pairs of alleles when multiple alleles exist
Example: Multiple AllelesHuman blood type is controlled by three
alleles : IA, IB and i. Alleles IA and IB are dominant over i IA and IB are codominant
Phenotype (blood type) GenotypesA IA IA or IAiB IB IB or IBi
AB IA IB
O ii
http://www.pennmedicine.org/health_info/images/19450.jpg
Problem: Multiple Alleles Show the cross between a mother who has type O
blood and a father who has type AB blood.
- IAi (2) IBi (2)- ratio 1:1
- type A blood (2); type B blood(2)- ratio 1:1
GENOTYPES:
PHENOTYPES:
i i
IA
IB
IAi
IBi
IAi
IBi
Problem2: Multiple AllelesShow the cross between a mother who is
heterozygous for type B blood and a father who is heterozygous for type A blood.
- IAIB (1); IBi (1); IAi (1); ii (1)- ratio 1:1:1:1
- type AB (1); type B (1) type A (1); type O (1)- ratio 1:1:1:1
GENOTYPES:
PHENOTYPES:
IA i
IB
i
IAIB
ii
IBi
IAi
http://duongchan.files.wordpress.com/2007/05/abobloodsystem.jpg
http://image.wistatutor.com/content/feed/tvcs/blood_type5B15D.jpg
Rhesus Factor The Rhesus factor, also
known as the Rh factor, gets its name from experiments conducted in 1937 by scientists Karl Landsteiner and Alexander S. Weiner.
Involved Rabbits which when injected with the Rhesus monkey’s red blood cells, produced an antigen present in the red blood cells of many humans http://content9.clipmarks.com/blog_cache/latimesblogs.latimes.com/img/E0C83714-56E5-4757-B9F1-604FCE5643C3
Rhesus Factor: The Rhesus factor is an
antigen (a protein) that exists on the surface of red blood cells. If a person has either two
(+) genes for Rh or one (+) and one (-) Rh gene, they will test Rh(+).
A person will be negative only if they have 2 (-).
It is very important in terms of babies Example: An Rh(-) mother has a Rh (+)
baby, she will make antibody against the Rh(+) fetus
Relevance of Rh Factor & ABO Typing?
To do: Blood type WS Genetics: Multiple Allele Traits WS
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