FDA-MANDATED ALTERNATIVE TO BISPHENOL-A Kristina Lenn Kevin Miles Gregory Jackett Isaac Norton...
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- Slide 1
- FDA-MANDATED ALTERNATIVE TO BISPHENOL-A Kristina Lenn Kevin
Miles Gregory Jackett Isaac Norton August 5, 2010
- Slide 2
- Foreshadow Introduction Effects of BPA on Human Physiology
Possible Alternative Plastics to BPA Manufacturing Analysis
Conclusion/Recommendation Questions
- Slide 3
- Introduction Nalgene water bottles BPA usage FDA
regulations
- Slide 4
- Meet the Team Kristina Lenn Project Manager Bachelor of Science
in chemical engineering with an emphasis in biological engineering
Research on molecular modeling and computer simulation Worked with
Nalgene for one year
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- Meet the Team Kevin Miles Team Leader during the Project
Proposal Bachelor of Science in chemical engineering with an
emphasis in biological engineering Research on tissue engineering
Worked with Nalgene for one year
- Slide 6
- Meet the Team Gregory Jackett Team Leader during the Final
Presentation Bachelor of Science degree in chemical engineering
with emphasis in molecular engineering and nanotechnology Research
on fatigue-induced muscle injury Worked with Nalgene for one
year
- Slide 7
- Meet the Team Isaac Norton Team Leader during the Final Report
Bachelor of Science in chemical engineering with an emphasis in
product and process design Work experience in quality control
Worked with Nalgene for one year
- Slide 8
- Background BPA=Bisphenol-A Polycarbonate Chemical in water
bottles and pop cans
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- Problem Recognized by the human body as estrogen Absorbed by
breast tumor cells Promote breast and prostate tumor growths
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- Task BPA effects Harmless Alternatives Manufacturing
Techniques
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- BPA EFFECTS ON HUMAN PHYSIOLOGY Kevin Miles
- Slide 12
- A Look Ahead Previous Statements Enviornmental exposure to BPA
BPA Leeching The Endocrine system BPA linked to cancer
Conclusion
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- ~ 25 ng/kg/day 50,000 ng/kg/day
http://www.google.com/imgres?imgurl=http:// onwardstate.com/wp-
content/uploads/2008/12/water_bottle-
300x300.jpg&imgrefurl=http://onwardstate.com
/2008/12/20/water-water-everywhere-but-a- storage-
dilemma/&usg=__qNetutbQEJVjtGWRfq72AO1L
wVU=&h=300&w=300&sz=11&hl=en&start=0&t
bnid=WsPcp- pgT6AipM:&tbnh=115&tbnw=114&prev=/imag
es%3Fq%3DWater%2BBottle%26um%3D1%26hl
%3Den%26sa%3DN%26rlz%3D1G1GGLQ_ENUS
367%26biw%3D740%26bih%3D411%26tbs%3Di
sch:1&um=1&itbs=1&iact=rc&dur=244&ei=xTV
PTOe5HZKlnQemi6CQBw&page=1&ndsp=10&ve d=1t:429,r:6,s:0
Human Exposure: 52-74ng/kg/day
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- How does the endocrine system work?
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- BPA increased the level of hormone receptors produced by a
prostate gland cell Some dosages of BPA were environmentally
relevant
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- An increase in cell receptors fuels growth of the cell Cells
can proliferate out of control, resulting in cancerous tumor
cells.
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- Conclusions BPA is harmful in lower doses BPA can leech into
food/beverages at relevant levels BPA exposure increases risk of
cancer
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- ALTERNATIVE POLYMERS Gregory Jackett
- Slide 23
- The Line up The Candidates Strength Toughness Liquid Stability
UV Stability Thermal Stability The Ranking
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- PETE(Polyethylene terephthalate)
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- Atactic Polystyrene(PS)
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- Eastman Tritan Copolyester
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- Strength
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- Toughness
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- Liquid Stability
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- UV Stability Copolyester?
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- Thermal Stability
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- The Ranking Copolyester PETE Polystyrene
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- MANUFACTURING ANALYSIS Isaac Norton
- Slide 34
- Forecast Polymerization Method Safety Quality Retooling
Ranking
- Slide 35
- Method
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- Safety
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- Reaction Heat Runaway
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- Quality
- Slide 39
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- The Ranking Copolyester PETE Polystyrene
- Slide 41
- Conclusions Hazardous in small concentrations Carcinogenic
developmental changes Copolyesters better material properties PETEs
better safety and quality properties
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- Our Solution Is PETE
- Slide 43
- Just a Reminder The Problem BPA Effects Possible Alternatives
Manufacturing Comparison The Solution
- Slide 44
- References http://www.intuitive-recruitment.co.uk/
http://fondnessforreading.blogspot.com/2008/12/melting.html
http://jalopnik.com/276775/wrecking-ball-on-the-loose
http://www.better-leadership.com/great-offices.html
http://www.greenerist.com/2009/02/green-tip-get-a-bpa-free-water-bottle/
http://health.allrefer.com/health/cancer-ovarian-cancer-metastasis.html
http://www.tuxedoranch.com/images/featured/bpa-free-1.png
http://www.sitnews.us/MacDougall/111207_PETE.jpg
http://www.extension.iastate.edu/newsrel/reiman/PolystyrenePot.jpg
http://www.innovationlab.eastman.com/NR/rdonlyres/4C99D9B3-B19A-4FD5-A60F-
8115B0DF5064/0/example_lrg_camelbak1.jpg
http://www.eastman.com/Brands/Eastman_Tritan/PublishingImages/TritanWater.jpg
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- References http://i1.treklens.com/photos/5947/dscn0425c.jpg
http://grail.cs.washington.edu/projects/office/dewey/china/photos/yunnan/hutiaoxia
/middle/middle14.jpg
http://www.jcu.edu/Philosophy/gensler/nc/images/10.jpg
http://faculty.uscupstate.edu/llever/Polymer%20Resources/Isomerism.htm
http://en.wikipedia.org/wiki/File:Ester-general.svg Taylor &
Francis Group. (2010) Polymers, a property database. Retrieved from
http://poly.chemnetbase.com http://poly.chemnetbase.com
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- QUESTIONS?