Embase: Tips and tricks for trainers - 27 Feb 2013

Tips and tricks for trainers

Your presenter: Ann-Marie Roche

Welcome to our Embase webinar program!

Agenda

• Tools• Demonstrating value with case study• Guiding users through…

o Initial investigationo Setting up search strategieso Refining, editing and managing search results

• Q&A

• Webinar control panel:o ‘chat’ or ‘ask a question’ for

questions and commentso Option for full screen view

• Q&A during and time at end.

Need to know

Tools

• Info siteoWebinarso FAQsoWhite papers, including MEDLINE in Embaseo Newslettero Links to videos on Training Desk

• NEW Training and Support site coming in April!

DEMONSTRATING VALUE

Emtree: Biomedical thesaurus, over 60k terms

Embase: Fully indexed: Over 8,000 journals, 1974-

MEDLINE: 2,500 journals unique to Embase, mapped to Embase

indexing, 1950- (including MEDLINE Classic)

Embase Classic:

Digitally scanned and

re-indexed, 1947-1973

AIP and In Process:

Indexing added, from 2009

Conference Abstracts:

Indexing added, from 2009

1947 1950 1974 2009

http://www.embase.com/info/what-is-embase/coverage

Content overview

2000 25003000

5.5m 9m10m

MEDLINEEmbase

[embase/lim] NOT [medline]/lim

Content overlap

8

Conference proceedings

Very powerful Search

Environment

...by including literature and information resources in a timely manner

...by reading full-text to identify drugs, diseases, adverse affects,

clinical trials, drug trade names etc.

...by enabling advanced search filters to drill down a comprehensive search to a

relevant and manageable record set

Scientific Journals

In Press (unpublished)

...by allowing users to automate searching and result management

Email alerting API Interoperability

Deep indexing using own taxonomy (EMTREE)

We make sure you don’t miss any

biomedical literature

The only close alternative is reading

all the articles

Good precision and recall balance

Automation and documentation

How is Embase delivering value?

Case study

A clinician is working on a systematic review for publication. She needs to adhere to certain guidelines to ensure she has conducted a through search of the literature.

Question

Are there any risks associated with the administration of antibiotics together with digoxin in a patient with congestive heart failure who has contracted pneumonia?

Articles like this contain vital information…

Comprehensive searching in Embase

11

2 sets of results…Why are the results so different and

does it matter…?

23 synonyms as well as ‘antibacterial agent’ are searched simultaneously as well as over 38 narrower

terms (including moxifloxacin).

No simultaneous searching of synonyms or narrower terms= Only ‘antibacterial

agent’ is searched and this does not find all the vital information

Our article is found in the Embase results…

…Not in our non-thesaurus assisted search

2 thesaurus assisted searches but different results? There is unique

content such as conference abstracts? Anything else?

Our article is found in the Embase results…

… Not in MEDLINE, as MEDLINE does NOT index digoxin in this article.

Unique content in Embase

• ‘Embase is a rich source of reports of randomized trials that are either not included in MEDLINE or not indexed as trials in MEDLINE, especially reports in some languages other than English’.

• ‘In addition to searching CENTRAL, people looking for reports of randomized trials should search Embase, as well as MEDLINE, for reports published in recent years that have not yet been considered for inclusion in CENTRAL’.

Presented by Carol Lefebvre MLA 2010

Ref: Lefebvre et al. Emerging Themes in Epidemiology 2008 5:13

Questions

• What is the difference between AIP, In Process and fully indexed records and why does Embase have all 3?

• Where do conference abstracts come from?• Is all of MEDLINE in Embase? Therefore do I

NOT need to search both?

http://www.embase.com/info/UserFiles/Files/Coverage%20of%20Medline%20in%20Embase.pdf

INITIAL INVESTIGATION

Find the best terms for your search and include synonyms automatically with

autocomplete in Quick Search

Start searching…

Click on Disease Filter for example, to see which diseases are referenced with Januvia, either as a therapeutic area or side effect.

Check filters…

Find interesting search terms or drug and disease relationships without having to consult the full text.

Check articles for search terms…

START BUILDING YOUR SEARCH

Start with Emtree

24

Search for over 60K terms, including MeSH terms and over 30K

drug and chemical terms

Click here to search further in an Embase search form, mapping all

synonyms

Click here to the see the results, exploded

3 x updates per year. www.embase.com/info/emtree for

more information

Reviewing an Emtree term

25

Take note of any Synonyms listed

Consider the term’s History

Look at the CAS registry number(s) displayed

Read the entry provided from Dorland’s dictionary, when

available

Backposting

• Emtree terms changes such as trade name and now generic name – How do you find ALL articles, NOT only those indexed from the date of the new term?

• BACKPOSTING!

Review Question

27

• Tracking the efficacy of saxagliptin in treating diabetes type 2

• Comparing the efficacy/safety of dipeptidyl peptidase 4 inhibitors

• Investigate the use of subheadings, such as: ‘Pharmacokinetics’, ‘Adverse Drug Reaction’, ‘Drug Toxicity’

• Use explosion to investigate other depeptidyl peptidase 4 inhibitors

Building and combining searches

• Use single quotes to capture a phrase ‘diabetes mellitus’ for example (not with Autocomplete in Quick Search)

• Break up your search into individual searches, such as a drug search (in Drug Search form) and a disease search (in Disease Search form) and combine your results in Session Results

• Run your cursor over your search to Edit or copy to a Search Form for guided editing.

• Truncation and operators, AND, OR, NOT, NEXT, NEAR

Refer to http://info.embase.com/helpfiles for more guidance and links to materials such as the Quick User Guide.

REFINE, EDIT AND MANAGE

Review Question

30

Find disease management studies for Type II diabetes

• Look for your term in Emtree• Use the disease search form for disease

subheadings.• Use major focus to limit your results.

Refining your search

• Quick and Advanced Limits on Advanced, Drug and Disease Search forms

• Major Focus on all advanced forms – major drugs and diseases retrieved

• Field limits under Advanced Search box to search in specific fields such as article title, abstract, conference name, drug name etc

• Drug and Disease Subheadings to limit to specific concepts such as Adverse Drug Reaction, Drug Comparison and Side Effect.

• Filters on Session Results page for specific diseases or study types for example

Check out our training videos at www.trainingdesk.elsevier.com/embase for more guidance.

More drug and disease combination searches

32

Find recent reports of cardiac adverse effects of beta 2 agonists in asthma treatment (e.g. formoterol, salmeterol,

indacaterol)

33

Are there any risks associated with the administration of antibiotics together with digoxin in a patient with congestive heart failure who has contracted pneumonia?

More drug and disease combination searches

34

Cost effectiveness of treatment with rosuvastatin compared with other statins

More drug and disease combination searches

Registering in Embase

35

•Setting up email alerts

•Saving your searches

•Staying up to date

Q&A