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GREEN BOOK 2
&
GREEN BOOK 3
Vegetable Oils
Nut Oils
CIR EXPERT PANEL MEETING
AUGUST 30-31, 2010
GREEN BOOK 2
Oils
CIR EXPERT PANEL MEETING
AUGUST 30-31, 2010
CIR Panel Book Page 1
Memorandum
To: CIR Expert Panel Members and Liaisons
From: Christina L. Burnett, Scientific Writer/Analyst
Date: July 30, 2010
Subject: Draft Report of the Vegetable Oil Group
The Scientific Literature Review (SLR) for this group of edible vegetable (and fruit) oils was announced April 23, 2010. A related SLR on edible nut oils was announced in June of this year, and is to be reviewed by the Panel at this meeting as well. If the Panel does not see any major differences in the overall toxicity potential of these two oil groups, it may consider combining the reports into one major edible oil report.
Both reports are taking a slightly new approach to reviewing multiple related ingredients at one time and are including oil ingredients that have previously been reviewed by the CIR Expert Panel, which are designated in italic print.
At the time that the SLR was announced, CIR sought the following additional information:
1. Manufacturing information about oils used in cosmetic formulation, particularly on methods used to remove non-fatty acid components (e.g., glycidol fatty acid esters);
2. Cosmetic grade specifications, if such exist, for oils used in cosmetic formulations.
3. Fatty acid composition for those oils covered in this report (where such information has not been provided or differs from what is presented).
4. Irritation and sensitization testing on cosmetics (finished products) containing specified concentrations of oils covered in this report.
5. Irritation and sensitization testing on those fatty acids present in the oils covered in this report that have previously not been reviewed by CIR.
6. Any other information that pertains to the safety of the use in cosmetics of the oils covered in this report.
Data on fatty acid compositions and cosmetic grade specifications, as well as an HRIPT studies on numerous oils have been received from the Personal Care Products Council and are incorporated in this draft report in Tables 3, 4, and 7, respectively. Due to the voluminous amount of unpublished data (800+ pages), data will be accessible online. Paper copies will be mailed out only by request.
Please note that the new use table is being employed in this report. The raw data from which the table was created along with any available concentration of use information have been included in the book materials.
If the data provided are sufficient for the Panel to assess the safety of these ingredients, a tentative conclusion should be developed regarding their safety in cosmetics, along with a rationale for that conclusion. The report will then be issued as a Tentative Safety Assessment. If additional data are needed, these should be identified and an Insufficient Data Announcement should be issued.
For your convenience, the materials for this report can also be found at http://www.cir-safety.org/aug10.shtml.
CIR Panel Book Page 2
CIR Panel Book Page 3
CIR Expert Panel History with Vegetable Oils April 2010 - CIR issued a Scientific Literature Review.
CIR Panel Book Page 4
Literature Search on Vegetable Oils
1
Ingredients Toxline PubMed
ChemIDplus HSDB CAplus NTIS HPV Merck USP
√ √ √ √ √ √ √ Ingredients were searched by Latin botanical (INCI) names, common names, and CAS numbers, when available. The list of ingredients searched is found in Table 1 of the vegetable oil report. Literature searches included chemical composition, fatty acid composition, dermal toxicity, irritation, and sensitization qualifiers.
Searches were performed between November 20, 2009 and March 30, 2010 and updated June 30 through July 8, 2010.
CIR Panel Book Page 5
Report
CIR Panel Book Page 6
Draft Report
Vegetable Oil, Related Plant-Derived Oils, and Other Derivatives
as Used in Cosmetics
August 30, 2010 The 2010 Cosmetic Ingredient Review Expert Panel members are: Chairman, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D.; Curtis D. Klaassen, Ph.D.; Daniel C. Liebler, Ph.D.; Ronald A Hill, Ph.D. James G. Marks, Jr., M.D.; Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The CIR Director is F. Alan Andersen, Ph.D. This report was prepared by Christina L. Burnett and Monice Fiume, Scientific Analyst/Writers.
© Cosmetic Ingredient Review 1101 17th Street, NW, Suite 412 " Washington, DC 20036-4702 " ph 202.331.0651 " fax 202.331.0088 "
cirinfo@cir-safety.org
CIR Panel Book Page 7
ii
TABLE OF CONTENTS
INTRODUCTION ................................................................................................................................................................. 1
Chemistry ............................................................................................................................................................................... 1
Processing ...................................................................................................................................................................... 2
Analytical Methods ............................................................................................................................................................ 2
Impurities ....................................................................................................................................................................... 2
Use ......................................................................................................................................................................................... 3
Cosmetic ............................................................................................................................................................................ 3
Non-Cosmetic .................................................................................................................................................................... 4
ANIMAL TOXICOLOGY .................................................................................................................................................... 4
OILS .............................................................................................................................................................................. 4
Dermal Irritation/Sensitization/Phototoxicity .................................................................................................................... 4
Adansonia Digitata Seed Oil [Baobab] .......................................................................................................................... 4
Carthamus Tinctorius (Safflower) Oil ........................................................................................................................... 4
Gossypium Herbaceum (Cotton) Seed Oil..................................................................................................................... 4
Elaeis Guineensis (Palm) Oil ......................................................................................................................................... 5
Olea Europea (Olive) Fruit Oil ...................................................................................................................................... 5
Oryza Sativa (Rice) Bran Oil and Germ Oil .................................................................................................................. 5
Sesamum Indicum (Sesame) Seed Oil ........................................................................................................................... 5
Triticum Vulgare (Wheat) Germ Oil ............................................................................................................................. 6
Zea Mays (Corn) Oil ...................................................................................................................................................... 6
Ocular Irritation ................................................................................................................................................................. 6
Adansonia Digitata Seed Oil [Baobab] .......................................................................................................................... 6
Elaeis Guineensis (Palm) Oil ......................................................................................................................................... 6
Gossypium Herbaceum (Cotton) Seed Oil..................................................................................................................... 6
Linum Usitatissimum (Linseed) Seed Oil ...................................................................................................................... 6
Olea Europea (Olive) Fruit Oil ...................................................................................................................................... 7
Oryza Sativa (Rice) Bran and Rice Germ Oil ................................................................................................................ 7
Ribes Nigrum (Black Currant) Seed Oil ........................................................................................................................ 7
Sesamum Indicum (Sesame) Seed Oil ........................................................................................................................... 7
Triticum Vulgare (Wheat) Germ Oil ............................................................................................................................. 7
Zea Mays (Corn) Oil ...................................................................................................................................................... 7
CARCINOGENICITY .......................................................................................................................................................... 7
CLINICAL ASSESSMENT OF SAFETY ............................................................................................................................ 8
Irritation/Sensitization/Allergenicity ................................................................................................................................. 8
Carthamus Tinctorius (Safflower) Oil ........................................................................................................................... 9
Elaeis Guineensis (Palm) Oil ......................................................................................................................................... 9
Gossypium Herbaceum (Cotton) Seed Oil..................................................................................................................... 9
Oryza Sativa (Rice) Bran Oil ......................................................................................................................................... 9
Persea Gratissima (Avocado) Oil ................................................................................................................................... 9
Sesamum Indicum (Sesame) Seed Oil ........................................................................................................................... 9
Triticum Vulgare (Wheat) Germ Oil ............................................................................................................................. 9
Ocular Irritation ................................................................................................................................................................. 9
Linum Usitatissimum (Linseed) Seed Oil ...................................................................................................................... 9
Ribes Nigrum (Black Currant) Seed Oil ...................................................................................................................... 10
Comedogenicity ............................................................................................................................................................... 10
Ribes Nigrum (Black Currant) Seed Oil ...................................................................................................................... 10
Case Studies ..................................................................................................................................................................... 10
Glycine Soja (Soybean) Oil ......................................................................................................................................... 10
Helianthus Annuus (Sunflower) Oil ............................................................................................................................ 10
Olea Europea (Olive) Fruit Oil .................................................................................................................................... 11
Persea Gratissima (Avocado) Oil ................................................................................................................................. 11
SUMMARY ......................................................................................................................................................................... 11
FIGURES AND TABLES ................................................................................................................................................... 14
Figure 2. Basic oil refinement flowchart.3 .................................................................................................................... 15
Table 2. Previously reviewed oil and fatty acid ingredients. ........................................................................................... 18
Table 3. Fatty acid composition. ...................................................................................................................................... 20
Table 4. Chemical properties. .......................................................................................................................................... 26
CIR Panel Book Page 8
iii
Table 5. Frequency of use according to duration and exposure. ...................................... Error! Bookmark not defined. Table 6. Non-food, non-cosmetic uses of edible oils.3 ................................................................................................... 42
REFERENCES .................................................................................................................................................................... 48
CIR Panel Book Page 9
1
INTRODUCTION
Vegetable oil and related edible seed oils have been safely consumed by humans for millennia. Because there is no
significant safety concern with these ingredients following oral exposure and their general biology is well characterized due to
extensive use in food materials, this safety assessment will focus solely on the basic chemistry, manufacturing/production, uses,
and irritation and sensitization data available on these oils as they are used in cosmetic ingredients. Various oils have been used on
the skin since antiquity. Initially used for anointing in religious ceremonies, oils and their components have long been used on the
skin for cosmetic purposes. The full list of ingredients this report covers, which includes oils, hydrogenated oils, unsaponifiables,
oil fatty acids, and simple salts, is found in Table 1. For the sake of brevity, the common name of the oil, when available, will be
used throughout this report. While a large number of oils derived from plants are included in this literature review, there is a
commonality in that they all are mixtures of triglycerides containing fatty acids and fatty acid derivatives, the safety of which in
cosmetics have been established.
This report includes cosmetic ingredients that have been previously reviewed by the Cosmetic Ingredient Review Expert
Panel. The ingredients, their conclusion, and published citations are found in Table 2. Previously reviewed fatty acids and
glyceryl triesters are also found in Table 2. This report excludes tree and ground nut oils, are covered in another safety
assessment.
CHEMISTRY
The group of ingredients characterized as fats and oils are the glyceryl esters of fatty acids (triglycerides) normally found
in plant tissues, including those which have been hydrogenated to reduce or eliminate unsaturation.1 Figure 1 is the general
structure of fats and oils. The raw oil may include plant sterols, pigments, glucosides, proteins, vitamins and impurities. The
extent to which these components are removed during processing varies. The available fatty acid compositions for the oils in this
report are found in Table 3. The available information on chemical properties and other constituents, including Food Chemicals
Codex specifications when provided, are found in Table 4.2
The percentage of chemical constituents in individual oil types is dependent on region where the oilseed plant is grown,
individual cultivars, and plant genetics.3 This is especially true in with rapeseed, where the erucic acid content varies from 1% to
58.6%. Low erucic acid rapeseed oil is also known as canola oil.
The nutritional content of these oils varies with oil type. For example, sunflower oil contains high levels of vitamins A,
D, and K, while palm oil is a rich source of vitamins A and E. Crude sunflower oil also has the highest content of vitamin E in the
form of α-tocopherol amongst vegetable oils.3
CIR Panel Book Page 10
2
Processing
Oils used in cosmetics are probably produced using the same process used in the food industry. Depending on the source,
oil may be directly expressed from the source (seed or pulp) followed by solvent extraction. Bailey’s Industrial Oil and Fat
Products states that the removal of pigments and polar materials is mandatory for most cosmetic applications.4 The process used
for oil refining for foods may be adequate for this purpose, or additional steps may be required. Special refining methods to yield
colorless and odorless oils are used by the cosmetic industry and include proprietary adsorption chromatography and supercritical
fluid extractions.
The majority of the oils presented in this report are produced either from mechanical extraction or solvent extraction or a
hybrid of both methods, known as prepress solvent extraction.3 In solvent extraction, hexane is the most commonly used solvent
as it is economical and has low toxicity potential when compared to other solvents. Seeds that are rich in oil can be cold pressed to
extract oil without the use of solvents.5
Af ter the initial extraction by methods such as solvent extraction, the crude (degummed) oil is often refined.3 The first
step is treating the oil with caustic soda to neutralize free fatty acids, hydrolyze phosphatides, and remove some colored pigments
and unsaponifiable materials. Soap stock is usually a by-product of this step. The next step involves bleaching the neutralized oil
with activated earth to further absorb pigments. The last major step in refining oil is deodorizing, which removes all oxidative
cleavage products that impart odor or flavor to the oil. Deodorization also removes tocopherols, sterols, and other minor
constituents of free fatty acids and undesirable foreign materials. Figure 2 is a flowchart of the basic refinement process.
After deodorization, oils can be further processed by hydrogenation, which makes oil more resistant to oxidative and
thermal damage, and by winterization, where oil is slowly cooled to promote formation of crystals that cause cloudiness and
filtered to remove the crystals.
Cosmetic grade vegetable oils may include a physical refining step that involves heating crude vegetable oil under
vacuum.5 This step allows for the removal of volatile components such as color compounds, odor compounds, and free fatty acids,
which gives the refined oil a lighter color, less odor, and lower acid values.
Analytical Methods
According to Crevel et al., a validated analytical methodology for establishing the protein content of oil is needed.6
Impurities
Many edible oils are derived from foods that are recognized as potent food allergens. It has been shown that often an
individual that is allergic to a food will generally not react to the refined oil.6 It should be noted that while the Panel has found a
general lack of clinical effects for edible oils already reviewed,7-15 other researchers have raised concerns. Halsey et al. reported
that Lowry protein determinations of cold-pressed and refined sunflower oil found 2-8 µg/ml protein,16 while Zitouni et al.
CIR Panel Book Page 11
3
reported trace amounts of protein in the refined oil.17 Olszewski et al. found 0.1-0.2 µg protein per g of peanut oil,18 while
Ramazzotti et al. reported finding IgE responsive residual proteins in peanut oil extracts.19 Porras et al. found soy protein is some
samples of soy oil, but not others.20 Awazuhara et al. reported 1.4-4.0 µg protein per 100 g of soy oil.21 Although Paschke et al.
found approximately 35 µg/ml protein content in refined soybean oil, no IgE-binding activity was detectable.22 The European
Medicines Agency (EMEA) Working Party on Herbal Medicinal Products concluded that soy and peanut products “should be
treated as allergenic unless they have an analytically-monitored non-allergenic specification and a safe maximum daily dose.”23
The EMEA found that threshold concentrations for induction of a protein contact dermatitis were not available and recommended
that “all medications for topical use containing soya or peanut products should be treated as allergenic.”
USE
Cosmetic
Oils are used in a wide variety of cosmetic products for their skin conditioning, occlusive, emollient, moisturizing and
other properties. A total of 124 of the 208 oil ingredients included in this safety assessment are reported to be used; 108 of the in-
use ingredients have never been reviewed by CIR, while 16 have been reviewed previously. For the ingredients being reviewed
for the first time, the frequency of use, as supplied to the Food and Drug Administration (FDA) by industry as part of the
Voluntary Cosmetic Registration Program (VCRP),24 and/or concentration of use, as supplied by industry in response to a Personal
Care Products Council (Council) survey,25,26 can be found in Table 5a. For the ingredients that have been reviewed previously, the
current and historical8,10,11,15,27-30 frequency and concentration of use is given in Table 5b. The 84 ingredients not currently
reported to be used are listed in Table 5c. Table 5d lists the 41 ingredients for which a concentration of use survey has not yet
been completed.
Sunflower seed oil has the greatest number of reported uses in cosmetic and personal care products, with a total of 1414.
Many other ingredients are used in an extensive number of formulations. For example, olive oil and soybean oil have 915 and 912
uses, respectively. Most of the in-use ingredients have uses in both leave-on and rinse-off product types, and many are used in
products that are applied around the eye or that can possibly be ingested. Some are used in products that involve mucous
membrane exposure, and a few are used in underarm deodorant formulations. Many of the products are used in formulations at
relatively high concentrations. Olive oil is used at up to 100%, avocado oil is used at up to 98%, sunflower seed oil at up to 96%,
and soybean oil at 95%.
The oil ingredients described in this report may be used in hair sprays, and effects on the lungs that may be induced by
aerosolized products containing these ingredients are of concern. The aerosol properties that determine deposition in the
respiratory system are particle size and density. The parameter most closely associated with deposition is the aerodynamic
diameter, da, defined as the diameter of a sphere of unit density possessing the same terminal settling velocity as the particle in
CIR Panel Book Page 12
4
question. In humans, particles with an aerodynamic diameter of ≤ 10µm are respirable. Particles with a da from 0.1 - 10µm settle
in the upper respiratory tract and particles with a da < 0.1 µm settle in the lower respiratory tract.31,32
Particle diameters of 60-80 µm and ≥80 µm have been reported for anhydrous hair sprays and pump hairsprays,
respectively.33 In practice, aerosols should have at least 99% of their particle diameters in the 10 – 110 µm range and the mean
particle diameter in a typical aerosol spray has been reported as ~38 µm.34 Therefore, most aerosol particles are deposited in the
nasopharyngeal region and are not respirable.
None of the oils or their related counterparts described in this report were restricted from use in any way under the rules
governing cosmetic products in the European Union.35
Non-Cosmetic
The primary uses for edible oils are for cooking. Palm oil is the world's most widely consumed edible oil (41.7 million
metric tons), followed by soybean oil, rapeseed oil, sunflower seed oil, cottonseed oil, peanut oil, palm kernel oil, coconut oil, ,and
olive oil.3,36 Non-food, non-cosmetic uses for edible oils are found in Table 6.
ANIMAL TOXICOLOGY
OILS
Irritation, sensitization and phototoxicity data available were reviewed and are summarized below. Information from
previous CIR reports on edible oils is identified by italics. No information was found for some of the oils listed in this report.
Dermal Irritation/Sensitization/Phototoxicity
Adansonia Digitata Seed Oil [Baobab]
In an alternative to the Draize test, 100% baobab oil was tested for dermal irritation in a MatTek EpiDerm ™ MTT
viability assay.37 The MatTek EpiDerm™ tissue samples were incubated with 100 µl of the test material for 1, 4, or 24 h along
with the positive control material, 1% Triton X-100, which was incubated for 4 or 9 h, and the negative control, undosed tissues,
which were incubated for 4 h. After treatment, the viability of the tissues was determined with MTT uptake and conversion. The
positive control provided expected results. The test material was classified as non-irritating.
Carthamus Tinctorius (Safflower) Oil
Undiluted safflower oil was minimally irritating in a repeat open patch test using rabbits and was not a primary irritant
or sensitizer in a maximization study using guinea pigs15.
Gossypium Herbaceum (Cotton) Seed Oil
Cosmetic formulations containing 3.4-8.97% hydrogenated cottonseed oil were not irritating to rabbit skin.10
CIR Panel Book Page 13
5
Elaeis Guineensis (Palm) Oil
Undiluted palm oil was practically non- to minimally irritating to rabbit skin.8 Palm oil, 5%, was non-allergenic in a
maximization study. A facial lotion containing 1.5% palm oil was not phototoxic in the phototoxicity yeast assay.
Olea Europea (Olive) Fruit Oil
Hartley and/or Himalayan guinea pigs were used to determine the sensitization potential of olive oil. 38 Single drops of a
USP-grade olive oil that had been stored in its original metal container for 10 yrs were applied to an area clipped free of hair on the
backs of 12 guinea pigs. (The composition of the oil was not determined.) Applications were made at 2-6 wk intervals over a
period of 5 mos. Four guinea pigs were treated similarly using store-bought virgin olive oil. None of the animals had a positive
reaction following the initial application of either oil. Using the 10-yr-old olive oil, 11 of 12 of the animals had a positive reaction
at some point during the study. Some, but not all, of these guinea pigs reacted consistently following the first positive reaction; 2
animals had only one positive reaction. Two guinea pigs in this group died by wk 16. In the group dosed with virgin olive oil, one
animal had a positive reaction at wk 2 and one animal had a positive reaction at wks 4 and 6.
Twenty-two guinea pigs sensitive to the 10-yr-old USP olive oil were used to determine cross-reactivity with the store-
bought virgin olive oil, another store-bought olive oil (not specified as virgin olive oil), corn oil, and peanut oil. The 5 oils were
applied simultaneously to the backs of the guinea pigs. Eighteen of the animals reacted to the virgin olive oil, and 18 reacted to the
other store-bought olive oil. (Overlap of these animals was not complete.) Cross-reactivity to corn or peanut oil was not observed.
The researchers then applied single drops of the unsaponifiable fraction of the 10-yr-old oil to 8 sensitized and 4 non-
sensitized guinea pigs. All of the sensitized animals reacted to the unsaponifiable fraction, while the non-sensitized animals did
not react.
Olive oil is used as a vehicle in the murine local lymph node assay (LLNA), an in vitro assay developed to assess a
chemical’s potential to induce allergic contact dermatitis in humans.39 The LLNA protocol states that the solvent/vehicle should
be selected on the basis of maximizing the test concentrations while producing a solution/suspension suitable for application of the
test substance. The recommended vehicle is acetone/olive oil (4:1 v/v).
Oryza Sativa (Rice) Bran Oil and Germ Oil
Undiluted rice bran oil was not irritating to rabbits, and in a guinea pig maximization study, no reactions were observed
when 55 was used at induction and 25 and 50% rice bran oil were used at challenge. 11 Rice germ oil was not a primary dermal
irr itant, and a rice bran oil/rice germ oil mixture, concentrations not stated, did not cause a contact allergy response. Undiluted
hydrolyzed rice protein was also not irritating or sensitizing. Undiluted rice bran oil and rice germ oil, ≤75%, were not
phototoxic or photosensitizing.
Sesamum Indicum (Sesame) Seed Oil
CIR Panel Book Page 14
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Undiluted sesame oil was non- or minimally irritating to rabbit skin.30
Tr iticum Vulgare (Wheat) Germ Oil
Wheat germ oil, undiluted and at 2% in formulation, was non- to mildly irritating, and undiluted wheat germ oil was not
sensitizing to guinea pigs.13
Zea Mays (Corn) Oil
A group of 6 Hartley and/or Himalayan guinea pigs were used to determine the sensitization potential of store-bought
corn oil. 38 None of the animals had a positive reaction following the initial application. Two animals had positive reactions
following application at wks 4 and 6, while one animal had a positive reaction following application at wk 12.
Ocular Irritation
Adansonia Digitata Seed Oil [Baobab]
In an alternative to the Draize rabbit eye test, 100% baobab oil was tested for ocular irritation in a MatTek EpiOcular ™
MTT viability assay.37 The MatTek EpiOcular™ tissue samples were treated with 100 µl of the test material for 16, 64, or 256
minutes along with the positive control material, 0.3% Triton X-100, which was treated for 15 or 45 minutes, and the negative
control, tissue culture water, which was treated for 16 minutes. After treatment, the viability of the tissues was determined with
MTT uptake and conversion. The positive control provided expected results. The test material was classified as non-irritating.
Elaeis Guineensis (Palm) Oil
Undiluted palm oil and cosmetic lotions and creams containing 1.5-2.0% palm oil were minimally irritating to the eyes of
rabbits, while one lotion containing 1.5% palm oil was moderately irritating.8 Hydrogenated palm oil suppositories were mildly
ir ritating to rabbit eyes.
Gossypium Herbaceum (Cotton) Seed Oil
Cosmetic formulations containing 3.4-12.3% hydrogenated cottonseed oil were mildly irritating to the eyes of rabbits.10
Lin um Usitatissimum (Linseed) Seed Oil
A mascara containing 9.4% linseed oil was tested for eye irritation potential in an in vitro study using neutral red release
(NRR), hen’s egg test on chorio-allantoic membrane (HET-CAM), and reconstituted human epithelial culture (REC) assays.40 For
the NRR assay, the test product was diluted at 0%, 5%, 15%, 25%, 35%, and 50% in mineral oil. The NR50 of the test product was
greater than 50% and the test product was considered slightly cytotoxic. In the HET-CAM assay, the score was 6.25 and the test
product was considered moderately irritating when applied under a 67.1% solution in mineral oil. Finally in the REC assay, the
cumulative simplified mean cytotoxicity index (SMCI) was calculated to be 0.25 and the test product was considered slightly
cytotoxic when applied under a 66.9% solution in mineral oil. Overall, the study concluded that the mascara containing 9.4%
linseed oil may be slightly irritating.
CIR Panel Book Page 15
7
Olea Europea (Olive) Fruit Oil
The ocular irritation potential of high purity olive oil was evaluated using in vivo and in vitro testing.41 In vivo, a Draize
test was conducted using New Zealand rabbits. (The number of animals used was not specified.) Undiluted olive oil was not an
ocular irritant in this test. Using human conjunctival epithelial cells in an in vitro study, olive oil did not induce cellular necrosis
or apoptosis.
Oryza Sativa (Rice) Bran and Rice Germ Oil
A mixture of rice bran oil and rice germ oil, concentrations not stated, were not irritating to rabbit eyes.11 Undiluted rice
bran oil was considered minimally irritating, and rice germ oil, concentration not stated, was not a primary irritant.
Ribes Nigrum (Black Currant) Seed Oil
A 50% dilution of an eye mask containing 0.2% black currant seed oil was tested in a HET-CAM assay.42 Two eye gels
with vitamin E at 50% were used as reference products. The average score was 2.00, where a mean score of 0-4.9 considered
“practically none” for irritation potential.
Sesamum Indicum (Sesame) Seed Oil
Undiluted sesame oil was non- to minimally irritating to rabbit eyes, and a lipstick containing 10-11% sesame oil was not
an ocular irritant.30
Tr iticum Vulgare (Wheat) Germ Oil
Undiluted wheat germ oil was, at most, a minimal ocular irritant, and 2% in a water emulsion was not irritating.13
Zea Mays (Corn) Oil
The ocular irritation potential of high purity corn oil was evaluated using in vivo and in vitro testing.41 In vivo, a Draize
test was conducted using New Zealand rabbits. (The number of animals used was not specified.) Undiluted corn oil was not an
ocular irritant in this test. Using human conjunctival epithelial cells in an in vitro study, corn oil did not induce cellular necrosis or
apoptosis.
CARCINOGENICITY
The safety of glycidol fatty acid esters in refined vegetable oils was assessed by IARC. Glycidol was determined to be a
Group2A (probably carcinogenic to humans) chemical while Glycidol Fatty Acid Esters was determined to be a Group 3 (not
classifiable as to carcinogenicity to humans) chemical.43,44
The Federal Institute for Risk Assessment in Germany released a summary of their initial evaluation of the assessment of
levels of glycidol fatty acid esters detected in refined vegetable fats.45 While acknowledging that the levels of glycidol that may be
CIR Panel Book Page 16
8
released from glycidol fatty acid esters are not known, the evaluation noted that glycidol is classified as probably carcinogenic to
humans. The evaluation was based on findings of the German Chemical and Veterinary Test Agency (CVUA).
In a presentation by Weisshauer from the CVUA, the conversion of glycidol to 3-chloropropanediol was presented as an
artifact of the analytical method, and it appeared to be the 3-chloropropanediol that was detected its indicative of the presence of
glycidol.46 The levels of 3-chloropropanediol were negligible at the crude oil, degummed, neutralized, and bleached stages, but
levels were significant at the deodorized stage.
CLINICAL ASSESSMENT OF SAFETY
Edible oils are commonly believed to be safe for use on the skin.4 de Groot notes that no documentation exist to show that
high quality edible lipids cause adverse reactions in normal individuals (except for potential comedogenicity).47 Very few reports
of adverse reactions to cosmetic use of edible oils have been reported.
Irritation/Sensitization/Allergenicity
Many edible oils are derived from foods that are recognized as potent food allergens. It has been shown that often an
individual that is allergic to a food will generally not react to the refined oil.6 A prime example is peanut oil. While the safety of
peanut oil is not being addressed in this assessment, it is being discussed here to demonstrate that although a food might cause
allergic reactions, the oil usually does not. Peanuts are extremely allergenic to a large population, but reaction to the oil is rare. In
its safety assessment on peanut (Arachis hypogaea) oil, the Expert Panel noted that the major concern associated with allergic
reactions to peanuts is the protein.9 The protein does not partition into the refined oil, and therefore the oil is safe for use in
cosmetics. Crevel et al. also concluded that chemically refined peanut oil is safe for the majority of peanut allergic individuals.6
They stated that “as peanut is acknowledged to be one of the most potent food allergens, it is reasonable to extrapolate the
conclusions drawn up for peanut oil to other edible oils.” However, they concede that validated analytical methodology for
establishing the protein content of oil is needed.
In support of the conclusions stated earlier, Crevel et al. also examined the allergenicity of some other oils. Very few
instances of allergic reactions to other major edible oils have been reported. Even sesame oil, which differs from the other oils in
that it is used as a flavorant and therefore is not as refined and expected to contain significantly more protein that the other edible
oils, has had very few reports of allergic reaction. Additional studies demonstrating safety are summarized later in this section.16,48
Specific information on clinical dermal irritation and sensitization findings from previous CIR reports on edible oils are
described below and are identified by italics. New clinical irritation and sensitization data is summarized in Table 7.
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Carthamus Tinctorius (Safflower) Oil
Cosmetic formulations containing 3-5% safflower oil were not irritating to humans in occlusive patch tests and were not
primary irritants or sensitizers in repeated insult patch tests.15
Elaeis Guineensis (Palm) Oil
Palm oil, 15% in petrolatum or cosmetic formulations containing 1.0-2.0%, was not an irritant or sensitizer in clinical
studies.8 Bar soap flakes, tested at dilutions that contained ≤ 2.13% palm kernel oil, were not irritating or sensitizing.
Gossypium Herbaceum (Cotton) Seed Oil
In a clinical patch test, the irritation potential of a cosmetic formulation containing 3.4% hydrogenated cottonseed oil
was mildly low, and the severity of reaction to 10.4% hydrogenated cottonseed oil was acceptably low in a use study.10 Cosmetic
formulations containing 10.6-20.86% hydrogenated cottonseed oil were not irritating or sensitizing. Patients that were
hypersensitive to cottonseed proteins were not sensitive to cottonseed oil in a skin prick test.
Oryza Sativa (Rice) Bran Oil
Rice is generally regarded as hypoallergenic, although some case studies of allergic reactions to raw rice have been
reported.11 In clinical testing, formulations containing 1.04-8.0% rice bran oil were not irritating or sensitizing, and formulations
containing 1.04% rice bran oil were not photosensitizing. Hydrolyzed rice protein was not irritating to human subjects.
Persea Gratissima (Avocado) Oil
Avocado was not an irritant or sensitizers when human subjects were patch tested with cosmetic formulations containing
up to 10.7% avocado oil or in patch tests using 100% avocado oil.14
Sesamum Indicum (Sesame) Seed Oil
In clinical testing, undiluted sesame oil was not irritating.30 Cosmetic formulations containing 8-14.3% sesame oil were
non- to essentially non-irritating. Prophetic patch testing with formulations containing 10-11% sesame oil were not irritating with
or without UV light. Patients with contact allergy to sesame oil were patch tested, and most had positive reactions to sesamol,
sesamin, and sesamolin.
Triticum Vulgare (Wheat) Germ Oil
In clinical testing, wheat germ oil was not an irritant or a sensitizer.13
Ocular Irritation
Linum Usitatissimum (Linseed) Seed Oil
The ocular irritation potential of a mascara containing 9.4% linseed oil was tested in 33 female subjects for 4 weeks.49 Of
the 33 subjects, 16 were contact lens wearers and the remaining 17 were self-assessed sensitive eye non-contact lens wearers. One
subject dropped out of the study for non-treatment related reasons. Subjects were evaluated with subjective questionnaires
CIR Panel Book Page 18
10
regarding ocular sensation following product use as well as with objective ophthalmic findings. Trace increases in palpebral
conjunctival irritation were observed in only one subject, but this result was thought to be non-treatment related by the study
investigators. No subjective irritation was reported and no adverse events were reported. The study concluded that the test
material was clinically safe for use by contact lens wearers and self-assessed sensitive eye non-contact wearers.
Ribes Nigrum (Black Currant) Seed Oil
An in-use 4 week study was conducted on an eye mask that contained 0.2% black currant seed oil (undiluted) in 52
subjects.50 Subjects were evaluated by an ophthalmologist and a dermatologist at baseline and at the end of the study. No adverse
reactions were observed. The eye mask was considered ophthalmologist tested and safe for contact lens wearers.
Comedogenicity
Ribes Nigrum (Black Currant) Seed Oil
A comedogenicity study of an eye mask containing 0.2% black currant seed oil (undiluted) was performed on 6
subjects.51 The test material was applied with occlusive patches. The average score was 0.00 comedones/cm2. The eye mask was
found to be non-comedogenic.
Case Studies
Glycine Soja (Soybean) Oil
Seven patients with a history of immediate hypersensitivity reaction after the ingestion of soybeans were enrolled in a
double-blind crossover study.48 The patients were first skin tested by the puncture method with a crude whole soybean extract, a
partially hydrogenated oil, a non-hydrogenated oil, and a cold-pressed soybean oil. Olive oil from a retailer was used as a negative
control. Since all 7 patients had negative skin tests to the oils and positive reactions to the crude soybean extract, they were
challenged orally with capsules of each of the oils in random order on 4 separate days. None of the patients reacted to the oral
challenges. The researchers remarked that while a reaction to the cold-pressed soybean oil did not occur in this study, cold-pressed
oils may contain soybean protein and should be avoided.
The sera from 4 patients with known allergy to soybean was used to examine the allergenicity of soy oil proteins.21
Neither the IgE nor the IgG4 in the sera reacted to protein in the soy oil.
Helianthus Annuus (Sunflower) Oil
Two cases were reported of patients having anaphylactic reactions following ingestion of sunflower seeds.16 No
reactions were seen upon oral or open challenge with refined or cold-pressed sunflower oils, both of which were shown to contain
detectable amounts of protein. However, in a case report of a woman who had been desensitized to mugwort (a member of the
Compositae family) pollen for a year, but then had an anaphylactic reaction to sunflower (also a member of the Compositae
family) seeds, it was found that she had a delayed positive reaction to sunflower oil in a skin prick test.52 Prick test results with 10
CIR Panel Book Page 19
11
control subjects were negative. In an oral challenge test, a delayed reaction was again observed, with symptoms occurring 2.25-8
h after administration.
Olea Europea (Olive) Fruit Oil
Throughout the literature, it is stated that sensitization to olive oil is considered rare. Case reports have been described,
however, and generally involved patients with venous eczema, some type of dermatitis or lesion, or an occupational exposure.
Patch testing with olive oil produced positive reactions in most of these cases, and these results were usually regarded as
allergenic. The concentrations of olive oil tested were not always given, but when stated, test concentrations giving positive
results, ranged from 30-100%. In some cases, the constituents of olive oil were tested as well, but the results of that testing were
negative.53-60
Kränke et al. investigated whether the reactions to olive oil were contact sensitization or irritation, using open and
occlusive testing. They concluded that olive oil presented as a weak irritant rather than a contact sensitizer in the few case studies
they observed. The capacity to produce an irritant result was increased using occlusive conditions.61 Zipprich and Hauser
remarked that components capable of inducing an irritant reaction can form if the olive oil isn’t stored properly.62
Persea Gratissima (Avocado) Oil
A case study was reported in which a female subject had dermatitis around the eyes and earlobes.63 Patch testing with her
sunscreen resulted in positive results. In subsequent patch testing of the individual ingredients, a positive reaction to undiluted
avocado oil, but not to the active ingredient, was observed. Twenty controls subjects were used, and reactions to avocado oil were
not seen.
Sesamum Indicum (Sesame) Seed Oil
A case study was reported in which a woman applied a Chinese ointment containing sesame oil, resulting in pruritic
erythema, papules, and vesicles. 64 Patch testing was performed with the ointment and with the individual ingredients, including
undiluted sesame oil. Both the ointment and sesame oil produced positive reactions on days 2, 3, 4, and 11. The other components
did not cause a reaction. Results were negative in patch testing of sesame oil using 20 healthy subjects.
SUMMARY
The oils derived from vegetable and fruit plants are composed of mono-, di-, and triglycerides, free fatty acids and other
minor components, including natural antioxidants and fat-soluble vitamins. The percentage of chemical constituents and
nutritional content of individual oil types is dependent on region where the oil plant is grown, individual cultivars, and plant
genetics. Oils used in cosmetics are likely produced in the same manner as those used in the food industry. Oils may be expressed
CIR Panel Book Page 20
12
through mechanical or solvent extraction. The oils may undergo further refining to remove pigments, odors, unsaponifiable
materials, and other undesirables.
It has been shown that often an individual that is allergic to a food will generally not react to the refined oil. The CIR
Expert Panel has found a general lack of clinical effects for edible oils that they have already reviewed; however, other researchers
have raised concerns about the presence of residual proteins oils, such as peanut and soy. These ingredients may also contain
aflatoxins, a metabolic products of certain molds that are carcinogenic to humans. The FDA action level for aflatoxin in foods is
20 ppb.
Of the oils described in this report, sunflower seed oil has the most reported uses in cosmetic and personal care products
with a total of 1414 and is used at a maximum concentration of 96%. Oils are used in a wide variety of cosmetic products,
including use in hair spray and other aerosolized products. None of the oils or the related counterparts described in this report
were restricted from use in the European Union.
Oils not summarized in the animal toxicity section or clinical studies section of this report had no available data for
review.
In dermal irritation studies in animals, Adansonia Digitata seed oil [baobab], hydrogenated cottonseed oil, rice bran oil,
and rice germ oil were not irritating. Undiluted safflower oil was minimally irritating in rabbits, but it was not a primary irritant in
guinea pigs. Undiluted palm oil, sesame oil, and wheat germ oil were practically non-irritating to minimally irritating in rabbits.
Safflower oil, palm oil, rice bran oil, rice germ oil, and wheat germ oil were non-sensitizing in animal studies. Rice bran oil, rice
germ oil, and palm oil were not phototoxic in animals studies.
In animal ocular studies, Adansonia Digitata seed oil [baobab], olive oil, rice germ oil, black currant seed oil, 10-11%
sesame seed oil, 2% wheat germ oil, and corn oil were non-irritating. Undiluted palm oil and palm oil at 2% were minimally
irritating to rabbit eyes. Hydrogenated palm oil and 3.4% - 12.3% hydrogenated cottonseed oil were considered mildly irritating.
In a HET-CAM study, 9.4% linseed oil was slightly irritating. Undiluted rice bran oil and undiluted wheat germ oil were
minimally irritating to eyes, while undiluted sesame oil was non- to minimal ocular irritants.
Glycidol and glycidol fatty acid esters, possible constituents in refined vegetable oils, were determined to be Group 2A
(probably carcinogenic to humans) and Group 3 (not classifiable as to carcinogenicity to humans) chemicals, respectively, by
IARC.
Edible oils are believed to be safe for use on the skin and very few reports of adverse reactions have been reported. The
proteins that are responsible for allergenic responses in individuals with food allergies do not partition into refined oils.
CIR Panel Book Page 21
13
In previously reviewed oils, safflower oil, palm oil, hydrogenated cottonseed oil, rice bran oil, avocado oil, sesame oil,
and wheat oil were non-irritating and/or non-sensitizing in human studies. In many of the oils found in this report, no irritation
and/or sensitization reactions were observed in human repeated insult patch tests.
In clinical studies, 0.2% black currant seed and 9.4% linseed oil were not ocular irritants. Black currant seed oil at 0.2%
was also non-comedogenic. Cases of contact allergy have been reported for soybean oil, sunflower oil, olive oil, avocado oil, and
sesame seed oil.
CIR Panel Book Page 22
14
FIGURES AND TABLES
OCR
O
H2C
HC OCR'
O
H2C OCR"
O
-OCR, -OCR', and -OCR" may be the same or diff erent f atty acid radicals.
Figure 1. General structure of fats and oils.1
CIR Panel Book Page 23
15
-
Crude Oil
Degummed Oil Lecithin Sludge
Alkali Refined Oil Soap Stock
Salad Oil
Cooking Oil Salad and
Cooking Oil Partially
Hydrogenated Oil
Other Fatty Oil
Shortening Stock
Blended Oils
Margarine Stock
Bleached Oil
Salad Oil
Water
Alkali
Deodorization
Deodorization
Deodorization
Deodorization
Deodorization
Deodorization
Activated Earth
H2, Catalyst
Winterization & Deodorization
Figure 2. Basic oil refinement flowchart.3
CIR Panel Book Page 24
16
Tab
le 1
. Edi
ble
oils
and
thei
r de
rivat
ives
.*
Veg
eta
ble
(O
lus)
Oil
(CA
S N
o. 6
8956
-68
-3)
Hel
ian
thu
s A
nnuu
s (S
un
flow
er)
Se
ed O
il (C
AS
No.
800
1-2
1-6
) B
rass
ica
Na
pus
See
d O
il [R
apes
eed
]
Hyd
roge
an
ted
Veg
eta
ble
Oil
(CA
S N
o. 6
833
4-2
8-1
) H
elia
nth
us
Ann
uus
(Su
nflo
we
r) S
eed
Oil
Un
sap
onifi
able
s B
rass
ica
Ole
race
a A
cep
ha
la S
eed
Oil
[Ka
le]
Maj
or O
ils
Hyd
roge
na
ted
Sun
flow
er S
eed
Oil
Bra
ssic
a O
lera
cea
Ita
lica
(B
rocc
oli)
See
d O
il B
rass
ica
Cam
pes
tris
(R
ap
esee
d)
See
d O
il (C
AS
No.
800
2-1
3-9
) S
un
flow
er S
eed
Aci
d (
CA
S N
o. 8
4625
-38
-7)
Ca
mel
ina
Sat
iva
See
d O
il [F
als
e F
lax]
Bra
ssic
a C
amp
estr
is (
Ra
pes
eed
) O
il U
nsa
pon
ifiab
les
Ole
a E
uro
pea
(O
live)
Fru
it O
il (C
AS
No.
80
01-2
5-0
) H
ydro
gen
ate
d C
am
elin
a S
ativ
a S
eed
Oil
Hyd
roge
na
ted
Ra
pes
eed
Oil
(CA
S N
o. 8
4681
-71
-0)
Hyd
roge
na
ted
Oliv
e O
il C
am
ellia
Jap
onic
a S
eed
Oil
Pot
ass
ium
Rap
esee
da
te
Hyd
roge
an
ted
Oliv
e O
il U
nsa
pon
ifiab
les
Ca
mel
lia K
issi
See
d O
il [T
ea]
Rap
esee
d A
cid
O
live
Aci
d (
CA
S N
o. 9
2044
-96
-7)
Ca
mel
lia O
leife
ra S
eed
Oil
[Tea
See
d]
Sod
ium
Ra
pes
eed
ate
O
lea
Eu
rop
aea
(O
live)
Hu
sk O
il H
ydro
gen
ate
d C
am
ellia
Ole
ifera
Se
ed O
il
Can
ola
Oil
(CA
S N
o. 8
002
-13
-9; 1
209
62-0
3-0
) O
lea
Eu
rop
aea
(O
live)
Oil
Un
sap
onifi
ab
les
(CA
S N
o. 1
567
98-1
2-8
) C
am
ellia
Sin
ensi
s S
eed
Oil
Can
ola
Oil
Un
sap
onifi
ab
les
Pot
ass
ium
Oliv
ate
(CA
S N
o. 6
815
4-7
7-8
) C
aric
a P
apa
ya S
eed
Oil
[Pap
aya
] H
ydro
gen
ate
d C
an
ola
Oil
Sod
ium
Oliv
ate
(C
AS
No.
647
89-8
8-6
) C
ary
oca
r B
rasi
lien
se F
ruit
Oil
[Peq
ui]
Car
tham
us T
inct
oriu
s (S
affl
ower
) Se
ed O
il (C
AS
No.
800
1-23
-8)
Ory
za S
ativ
a (R
ice)
Bra
n O
il (C
AS
No.
685
53-8
1-1;
846
96-3
7-7)
C
hen
opod
ium
Qui
noa
See
d O
il [Q
uin
oa]
Hyd
roge
na
ted
Sa
fflow
er S
eed
Oil
Ory
za S
ativ
a (R
ice)
Ger
m O
il C
itru
llus
Lan
atu
s (W
ate
rmel
on)
Se
ed O
il
Pot
ass
ium
Sa
fflo
we
rate
R
ice
Bra
n A
cid
(CA
S N
o. 9
3165
-33-
4)
Citr
us
Au
ran
tifol
ia (
Lim
e) S
eed
Oil
Sa
fflo
wer
Aci
d H
ydro
gen
ate
d R
ice
Bra
n O
il C
itru
s A
ura
ntif
olia
(Li
me)
See
d O
il U
nsa
pon
ifiab
les
Sod
ium
Sa
fflow
era
te
Ory
za S
ativ
a (
Ric
e) S
eed
Oil
H
ydro
gen
ate
d L
ime
Se
ed O
il
Ela
eis
Gui
neen
sis
(Pal
m)
Oil
(CA
S N
o. 8
002-
75-3
) Se
sam
um I
ndic
um (
Sesa
me)
See
d O
il (C
AS
No.
800
8-74
-0)
Hyd
roge
na
ted
Lim
e S
eed
Oil
Un
sap
onifi
ab
les
Ela
eis
Gui
neen
sis
(Pal
m) K
erne
l Oil
(CA
S N
o. 8
023-
79-8
) H
ydro
gena
ted
Sesa
me
Seed
Oil
Citr
us
Au
ran
tium
Du
lcis
(O
ran
ge)
Se
ed O
il
Hyd
roge
nate
d P
alm
Oil
(CA
S N
o. 8
033-
29-2
; 685
14-7
4-9)
Se
sam
um I
ndic
um (
Sesa
me)
Oil
Uns
apon
ifia
bles
C
itru
s A
ura
ntiu
m D
ulc
is (
Ora
nge
) S
eed
Oil
Un
sap
onifi
ab
les
Hyd
roge
nate
d P
alm
Ker
nel O
il (C
AS
No.
689
90-8
2-9;
845
40-0
4-5)
So
dium
Ses
ames
eeda
te
Hyd
roge
na
ted
Ora
nge
See
d O
il
Pa
lm K
ern
el A
cid
Ses
am
um
Ind
icu
m (
Ses
am
e) S
eed
But
ter
Hyd
roge
na
ted
Ora
nge
See
d O
il U
nsa
pon
ifiab
les
Ela
eis
Gu
inee
nsi
s (P
alm
) B
utte
r (C
AS
No.
80
02-7
5-3
) Z
ea M
ays
(Cor
n) O
il (C
AS
No.
800
1-30
-7)
Citr
us
Gra
ndis
(G
rap
efru
it) S
eed
Oil
Ela
eis
Ole
ifera
Ke
rnel
Oil
Zea
May
s (C
orn)
Ger
m O
il C
itru
s G
rand
is (
Gra
pef
ruit)
See
d O
il U
nsa
pon
ifiab
les
Ela
eis
(Pa
lm)
Oil
Zea
May
s (C
orn)
Oil
Uns
apon
ifia
bles
C
itru
s P
ara
dis
i (G
rap
efru
it) S
eed
Oil
Pa
lm A
cid
Cor
n A
cid
(CA
S N
o. 6
8308
-50-
9)
Hyd
roge
na
ted
Gra
pef
ruit
See
d O
il
Hyd
roge
na
ted
Pa
lm A
cid
Pot
assi
um C
orna
te (
CA
S N
o. 6
1789
-23-
9)
Hyd
roge
na
ted
Gra
pef
ruit
See
d O
il U
nsa
pon
ifia
ble
s P
ota
ssiu
m P
alm
ate
M
inor
Oils
C
itru
s Li
mon
(Le
mon
) S
eed
Oil
(CA
S N
o. 8
508
5-2
8-5
)
Pot
ass
ium
Hyd
roge
na
ted
Pa
lmat
e A
ctin
idia
Chi
nen
sis
(Kiw
i) S
eed
Oil
Coi
x La
crym
a-J
obi (
Job
's T
ears
) S
eed
Oil
Pot
ass
ium
Pa
lm K
ern
ela
te
Ad
an
son
ia D
igita
ta O
il [B
aob
ab]
Cra
mb
e A
bys
sin
ica
See
d O
il [A
bys
sin
ian
Mu
sta
rd]
Sod
ium
Hyd
roge
na
ted
Pa
lma
te
Ad
an
son
ia D
igita
ta S
eed
Oil
Cuc
um
is S
ativ
us
(Cuc
um
ber
) S
eed
Oil
(CA
S N
o. 7
095
5-2
5-8
) S
odiu
m P
alm
ate
(CA
S N
o. 6
179
0-7
9-2
) H
ydro
gen
ate
d A
da
nso
nia
Dig
itata
See
d O
il C
ucu
rbita
Pep
o (P
um
pki
n)
See
d O
il (C
AS
No.
801
6-4
9-7
)
Sod
ium
Pa
lm K
ern
ela
te (
CA
S N
o. 6
1789
-89
-7)
Am
ara
nth
us
Hyp
och
ond
riacu
s S
eed
Oil
[Am
ara
nth]
H
ydro
gen
ate
d P
um
pkin
See
d O
il
Gly
cin
e S
oja
(S
oyb
ean
) O
il (C
AS
No.
80
01-2
2-7
) A
rctiu
m L
ap
pa S
eed
Oil
[Bu
rdoc
k]
Cyn
ara
Ca
rdun
culu
s S
eed
Oil
[Art
icho
ke]
(CA
S N
o. 9
230
29
-60
-1)
Gly
cin
e S
oja
(S
oyb
ean
) O
il U
nsa
pon
ifia
ble
s (C
AS
No.
91
770
-67
-1)
Arg
an
ia S
pin
osa
Ker
ne
l Oil
[Arg
an
] E
ute
rpe
Ole
race
a F
ruit
Oil
[Aca
i]
Hyd
roge
na
ted
Soy
bea
n O
il (C
AS
No.
80
16-7
0-4
) H
ydro
gen
ate
d A
rga
nia
Sp
inos
a K
ern
el O
il F
raga
ria A
na
na
ssa
(S
tra
wb
erry
) S
eed
Oil
So
y A
cid
(C
AS
No.
683
08
-53
-2)
Ast
roca
ryu
m M
uru
mu
ru S
eed
Bu
tter
[Mu
rum
uru
] F
raga
ria C
hilo
ensi
s (S
tra
wb
erry
) S
ee
d O
il
Pot
ass
ium
Soy
ate
S
odiu
m A
stro
cary
um
Mu
rum
uru
ate
F
raga
ria V
esca
(S
tra
wb
erry
) S
eed
Oil
Sod
ium
Soy
ate
A
ven
a S
ativ
a (
Oat
) K
ern
el O
il
Fra
garia
Virg
inia
na
(S
tra
wb
erry
) S
eed
Oil
Gos
sypi
um H
erba
ceum
(Cot
ton)
See
d O
il (C
AS
No.
800
1-29
-4)
Ba
ssia
But
yra
cea
See
d B
utte
r G
arc
inia
Ind
ica
See
d B
utte
r [K
oku
m]
Cot
tons
eed
Aci
d (C
AS
No.
683
08-5
1-0)
B
ass
ia L
atif
olia
See
d B
utte
r [M
ahw
a]
Gu
izot
ia A
bys
sin
ica
See
d O
il [R
amtil
]
Hyd
roge
nate
d C
otto
nsee
d O
il (C
AS
No.
683
34-0
0-9)
B
ora
go O
ffici
na
lis S
eed
Oil
[Bor
age
] (C
AS
No.
225
234
-12
-8)
Hip
pop
ha
e R
ham
noi
des
Oil
[Sea
-Buc
kth
orn]
* p
revi
ousl
y re
vie
wed
ingr
edie
nts
are
in
bold
and
ital
ics
CIR Panel Book Page 25
17
Tab
le 1
. Edi
ble
oils
and
thei
r de
rivat
ives
.*
Hip
pop
ha
e R
ham
noi
des
Fru
it O
il [S
ea-B
uckt
hor
n]
Hyd
roge
na
ted
Pa
ssifl
ora
Edu
lis S
eed
Oil
Hyd
roge
na
ted
Ra
spb
erry
See
d O
il
Hip
pop
ha
e R
ham
noi
des
See
d O
il [S
ea-B
uckt
hor
n]
Per
illa
Ocy
moi
des
See
d O
il [P
erill
a]
Scl
eroc
ary
a B
irrea
See
d O
il [M
aru
la]
Irvi
ngi
a G
ab
onen
sis
Ker
ne
l Bu
tter
[Dik
a] (
CA
S N
o. 1
922
30
-28
-7)
Per
sea
Gra
tissi
ma
(Avo
cado
) O
il (C
AS
No.
802
4-32
-6)
Sily
bu
m M
aria
num
See
d O
il [T
his
tle]
Lim
na
nth
es A
lba
(M
ead
owfo
am
) S
eed
Oil
(CA
S N
o. 1
5306
5-4
0-8
)
Hyd
roge
na
ted
Avo
cad
o O
il S
ola
nu
m L
ycop
ersi
cum
(T
oma
to)
See
d O
il
Hyd
roge
na
ted
Mea
dow
foa
m S
eed
Oil
P
erse
a G
ratis
sim
a (A
voca
do)
But
ter
Sol
an
um
Lyc
oper
sicu
m (
Tom
ato
) F
ruit
Oil
Lin
um
Usi
tatis
sim
um
(Li
nse
ed)
Se
ed O
il (C
AS
No.
800
1-2
6-1
) P
erse
a G
ratis
sim
a (A
voca
do)
Oil
Un
sap
onifi
ab
les
(CA
S N
o. 9
177
0-
40
-0)
Th
eob
rom
a C
aca
o (C
ocoa
) S
eed
But
ter
(CA
S N
o. 8
002
-31
-1)
Lin
seed
Aci
d (
CA
S N
o. 6
8424
-45
-3)
Sod
ium
Avo
cad
oate
S
odiu
m C
ocoa
But
tera
te
Luffa
Cyl
ind
rica
See
d O
il [L
uffa
] P
luke
net
ia V
olu
bilis
See
d O
il [S
ach
a In
chi]
Th
eob
rom
a G
ran
difl
oru
m S
eed
Bu
tter
[Cup
ua
cu]
(CA
S N
o.
394
236
-97
-6)
Lup
inu
s A
lbu
s S
eed
Oil
[Wh
ite L
up
ine]
P
runu
s A
rmen
iaca (A
pric
ot)
Ker
nel
Oil
(CA
S N
o. 7
286
9-6
9-3
) S
odiu
m T
heo
bro
ma
Gra
ndi
floru
m S
eed
ate
Lup
inu
s A
lbu
s O
il U
nsap
onifi
able
s H
ydro
gen
ate
d A
pric
ot K
ern
el O
il T
orre
ya N
uci
fera
See
d O
il [K
aya
]
Lyci
um
Ba
rba
rum
See
d O
il [G
oji B
erry
] H
ydro
gen
ate
d A
pric
ot K
ern
el O
il U
nsa
pon
ifia
ble
s T
ritic
um V
ulga
re (
Whe
at)
Ger
m O
il (C
AS
No.
800
6-95
-9;
6891
7-73
-7)
Man
gife
ra In
dic
a (
Man
go)
See
d O
il P
runu
s A
rmen
iaca
(A
pric
ot)
Ker
nel
Oil
Un
sap
onifi
able
s H
ydro
gen
ate
d W
hea
t G
erm
Oil
Man
gife
ra In
dic
a (
Man
go)
See
d B
utte
r P
runu
s A
viu
m (
Sw
eet
Ch
erry
) S
eed
Oil
Hyd
roge
na
ted
Wh
eat
Ger
m O
il U
nsa
pon
ifiab
les
Sod
ium
Man
gose
eda
te
Pru
nus
Dom
estic
a S
eed
Oil
[Pru
ne/
Plu
m]
Trit
icu
m A
estiv
um
(W
hea
t) G
erm
Oil
Mor
ind
a C
itrifo
lia S
eed
Oil
[Non
i] P
runu
s P
ersi
ca (
Pea
ch)
Ker
ne
l Oil
(CA
S N
o. 8
002
-78
-6; 8
023
-98
-1)
Trit
icu
m V
ulg
are
(W
hea
t) G
erm
Oil
Un
sap
onifi
able
s
Mor
inga
Ole
ifera
Se
ed O
il [B
en]
Hyd
roge
na
ted
Pea
ch K
ern
el O
il W
hea
t G
erm
Aci
d (
CA
S N
o. 6
893
8-3
2-9
)
Mor
inga
Pte
ryg
osp
erm
a S
eed
Oil
P
uni
ca G
ran
atu
m S
eed
Oil
[Pom
egra
nte]
V
acc
iniu
m C
orym
bos
um
(B
lueb
erry
) S
eed
Oil
Oen
oth
era
Bie
nni
s (E
veni
ng
Prim
rose
) O
il H
ydro
gen
ate
d P
unic
a G
ran
atu
m S
eed
Oil
Va
ccin
ium
Ma
croc
arp
on (
Cra
nber
ry)
See
d O
il H
ydro
gen
ate
d E
ven
ing
Prim
rose
Oil
Pyr
us
Ma
lus
(Ap
ple
) S
eed
Oil
Hyd
roge
na
ted
Cra
nber
ry S
eed
Oil
Org
ibn
ya C
ohun
e S
eed
Oil
[Coh
un
e]
Rib
es N
igru
m (
Bla
ck C
urr
ant)
See
d O
il (C
AS
No.
976
76-1
9-2
) V
acc
iniu
m M
yrtil
lus
See
d O
il [B
ilber
ry]
(CA
S N
o. 1
161
921
-09
-0)
Orb
ign
ya O
leife
ra S
eed
Oil
[Bab
ass
u] (
CA
S N
o. 9
107
8-9
2-1
) H
ydro
gen
ate
d B
lack
Cu
rra
nt S
eed
Oil
Va
ccin
ium
Viti
s-Id
aea
See
d O
il [L
igo
nb
erry
]
Orb
ign
ya S
pec
iosa
Ker
ne
l Oil
[Ba
bass
u]
Rib
es R
ub
rum
(C
urr
ant)
See
d O
il V
an
illa
Pla
nifo
lia F
ruit
Oil
[Van
illa
] (C
AS
No.
802
4-0
6-4
) B
aba
ssu
Aci
d R
osa
Can
ina
Fru
it O
il [D
og R
ose]
V
itis
Vin
ifera
(G
rap
e) S
eed
Oil
(CA
S N
o. 8
024
-22
-4)
Pot
ass
ium
Bab
ass
uat
e H
ydro
gen
ate
d R
osa
Ca
nina
Fru
it O
il S
odiu
m G
rap
esee
da
te
Sod
ium
Ba
bass
uat
e R
ubu
s C
ham
aem
oru
s S
eed
Oil
[Clo
udb
erry
] H
ydro
gen
ate
d G
rap
esee
d O
il
Pa
ssifl
ora
Edu
lis S
eed
Oil
[Pa
ssio
n F
ruit]
(C
AS
No.
87
676
-26
-1)
Rub
us
Ida
eus
(Ra
spb
erry
) S
eed
Oil
* p
revi
ousl
y re
vie
wed
ingr
edie
nts
are
in
bold
and
ital
ics
CIR Panel Book Page 26
18
Tab
le 2
. Pre
viou
sly
revi
ewed
oil
and
fatty
aci
d in
gred
ient
s.
Ingr
edie
nts
Pub
licat
ion
Dat
e C
oncl
usio
n
Oil
Ingr
edie
nts
Ca
rth
am
us
Tin
ctor
ius
(Sa
fflo
wer
) S
eed
Oil
(CA
S N
o. 8
001
-23
-8)
JAC
T 4
(5):
17
1-1
97,
198
5;
Re-
revi
ew
ed,
not
reo
pen
ed IJ
T 2
5(2
):1
-89
, 20
06
Sa
fe
Ela
eis
Gu
inee
nsi
s (P
alm
) O
il (C
AS
No.
80
02-7
5-3
)
IJT
19
(S2
):7
-28,
200
0 S
afe
E
laei
s G
uin
een
sis
(Pa
lm)
Ke
rnel
Oil
(CA
S N
o. 8
023
-79
-8)
Hyd
roge
na
ted
Pa
lm O
il (C
AS
No.
803
3-2
9-2
; 685
14-7
4-9
)
Hyd
roge
na
ted
Pa
lm K
ern
el O
il (C
AS
No.
68
990
-82
-9; 8
454
0-0
4-5
)
Gos
syp
ium
Her
ba
ceu
m (
Cot
ton
) S
eed
Oil
(CA
S N
o. 8
001
-29
-4)
IJT
20
(S2
):21
-29
, 200
1 S
afe
C
otto
nsee
d A
cid
(C
AS
No.
683
08-5
1-0
)
Hyd
roge
na
ted
Cot
ton
seed
Oil
(CA
S N
o. 6
833
4-0
0-9
)
Ory
za S
ativ
a (
Ric
e) B
ran
Oil
(CA
S N
o. 6
855
3-8
1-1
; 846
96
-37
-7)
IJT
25
(S2
):91
-120
, 20
06
Sa
fe
Ory
za S
ativ
a (
Ric
e) G
erm
Oil
Ric
e B
ran
Aci
d (C
AS
No.
93
165
-33
-4)
Ses
am
um
Ind
icu
m (
Ses
am
e) S
eed
Oil
(CA
S N
o. 8
008
-74
-0)
JAC
T 1
2(3
):2
61-2
77, 1
993;
A
men
ded
Fin
al R
epor
t, 20
09
Sa
fe
Hyd
roge
na
ted
Ses
am
e S
eed
Oil
Ses
am
um
Ind
icu
m (
Ses
am
e) O
il U
nsa
pon
ifiab
les
Sod
ium
Ses
am
esee
da
te
Zea
Ma
ys (
Cor
n)
Oil
(CA
S N
o. 8
001
-30
-7)
Fin
al R
epor
t, 2
008
S
afe
Z
ea M
ays
(C
orn
) G
erm
Oil
Zea
Ma
ys (
Cor
n)
Oil
Un
sap
onifi
able
s
Cor
n A
cid
(CA
S N
o. 6
830
8-5
0-9
)
Pot
ass
ium
Cor
nat
e (C
AS
No.
617
89
-23
-9)
Per
sea
Gra
tissi
ma
(Avo
cad
o) O
il (C
AS
No.
80
24-3
2-6
) JE
PT
4(4
):93
-10
3, 1
980
; R
e-re
vie
wed
, n
ot r
eop
ened
IJT
22
(1):
1-3
5, 2
003
S
afe
Trit
icu
m V
ulg
are
(W
hea
t) G
erm
Oil
(CA
S N
o. 8
006
-95
-9; 6
891
7-7
3-7
) JE
PT
4(4
):33
-45
, 19
80;
Re-
revi
ew
ed,
not
reo
pen
ed IJ
T 2
2(1
):1
-35
, 20
03
Sa
fe
Fat
ty A
cids
Ara
chid
onic
Aci
d (C
AS
No.
506
-32
-1)
JAC
T 1
2 (
5):
481
-55
9, 1
993
Insu
ffici
ent d
ata
Hyd
roxy
stea
ric A
cid
(C
AS
No.
106
-14
-9)
IJT
18
(S1
):1
-10,
199
9 S
afe
Lau
ric A
cid
(C
AS
No.
143
-07
-7)
JAC
T 6
(3):
32
1-4
01,
198
7;
Re-
revi
ew
ed,
not
reo
pen
ed IJ
T 2
5(2
):1
-89
, 20
06
Sa
fe
Myr
istic
Aci
d (
CA
S N
o. 5
44-6
3-8
)
Ole
ic A
cid
(C
AS
No.
11
2-8
0-1
)
Pa
lmiti
c A
cid
(C
AS
No.
57
-10
-3)
Ste
aric
Aci
d (
CA
S N
o. 5
7-1
1-4
)
CIR Panel Book Page 27
19
Ta
ble
2.
Pre
viou
sly
revi
ew
ed o
il a
nd fa
tty
aci
d in
gred
ien
ts (
cont
inu
ed)
.
I ngr
edie
nts
Pub
licat
ion
Dat
e C
oncl
usio
n
Gly
cery
l Tri
este
rs
Tril
au
rin
IJT
20
(S
4):
61
-94,
200
1 S
afe
Tria
rach
idin
T
ribeh
enin
Tric
ap
rin
Tric
ap
rylin
Trie
ruci
n T
rihep
tan
oin
Trih
epty
lun
dec
anoi
n
Trii
son
onan
oin
Trii
sop
alm
itin
Trii
sost
earin
Tril
inol
ein
Trim
yris
tin
Trio
cta
noi
n T
riole
in
Trip
alm
itin
Trip
alm
itole
in
Trir
icin
olei
n T
riste
arin
Triu
ndec
an
oin
Gly
cery
l Tria
cety
l Hyd
roxy
stea
rate
Gly
cery
l Tria
cety
l Ric
inol
eate
G
lyce
ryl S
tea
rate
Dia
ceta
te
CIR Panel Book Page 28
20
Tab
le 3
. Fat
ty a
cid
com
posi
tion.
Fat
ty A
cids
C
orn
Oil28
,65,
66 *
C
otto
n S
eed
Oil10
O
live
Oil3
Pal
m
Oil8
Pal
m K
erne
l O
il8 R
apes
eed
Oil3
Ful
ly
Hyd
roge
nate
d R
apes
eed
Oil2
Can
ola
Oil2
Saf
flow
er
See
d O
il15,6
7 S
esam
e S
eed
Oil7,
30
Cap
roic
(C
6)
0
.3
Cap
rylic
(C
8)
4
.4
Cap
ric (
C10
)
3.7
Laur
ic (
C12
)
0.2
4
8.3
Myr
istic
(C
14)
0.1
- 1
.7
2 T
race
1
.1
15.
6
< 1
.0
< 0
.2
<
0.5
Myr
isto
leic
(C
14:1
)
Pal
miti
c (C
16)
8-1
2; 8
-16.
5 2
1 7
.5 -
20
44
7.8
1
.5 -
3
3-5
.0
< 6
.0
2 7
.0 -
12.
0
Pal
mito
leic
(C
16:1
) 0
.2 -
1.6
0.3
- 3
.5
0.1
< 1
.0
<
0.5
Hep
tade
cano
ic (
C17
:0)
Ste
aric
(C
18)
2.5
- 4
.5; 0
-4
Tra
ce
0.5
- 3
.5
4.5
2
0.7
- 1
.3
38
-42
< 2
.5
3
.5 -
6.0
Ole
ic (
C18
:1)
19
– 49
; 20
-43
30
53
- 86
3
9.2
15.
1 1
2.1
- 57
.4
1 >
50
26
35
- 50
Lino
leic
(C
18:2
) 3
4 –
62; 5
0-6
6 4
5 3
.5 -
20
10.
1 2
.7
11.
4 -
22.1
<
1.0
<
40
.0
68
35
- 50
Lino
leni
c (C
18:3
) 0
-2
0
- 1
.5
0.4
8.3
- 1
2.5
< 1
4 T
race
<
1.0
Ara
chid
ic (
C20
) 1
T
race
T
race
0
.4
8
-10
.0
< 1
.0
Tra
ce
<1
.0
Eic
osen
oic
(C20
:1)
1
5
.6 -
3.1
<
1.0
<
2.0
<0
.5
Eic
osad
ieno
ic (
C20
:2)
Beh
enic
(C
22)
Tra
ce
42
-50
< 0
.5
<
0.5
Eru
cic
(C22
:1)
1 -
58.
6 <
1.0
<
2.0
Doc
osad
ieno
ic (
C22
:2)
Doc
osah
exae
noic
(C
22:6
)
Lign
ocer
ic (
C24
)
T
race
1
-2.0
<
0.2
Ara
chid
onic
(C
20:4
n6)
Ara
chid
ontr
ieno
ic
Oth
ers
0
.2
< C
14 =
<
0.1
; C2
4:1
=
< 0
.2
Tra
ce o
f co
mp
onen
ts
bel
ow
C1
4
Ole
ic/L
inol
eic
Sat
urat
ed, G
ener
al
*Sh
ad
owin
g id
entif
ies
pre
viou
sly
revi
ew
ed in
gred
ien
ts.
CIR Panel Book Page 29
21
Tab
le 3
. F
atty
aci
d co
mpo
sitio
n (c
ontin
ued.
)
Fat
ty A
cids
S
oybe
an
Oil3
Sun
flow
er
See
d O
il3 A
cai
Oil68
A
mar
anth
O
il69
Ap
ricot
K
erne
l Oil
3 A
rtic
hoke
O
il70
Avo
cado
O
il3 B
abas
su
Oil3
Ben
O
il71
Cam
elin
a (F
alse
F
lax)
See
d O
il72
Cap
roic
(C
6)
Cap
rylic
(C
8)
4
to
8
Cap
ric (
C10
)
4 t
o 8
Laur
ic (
C12
)
44
- 47
Myr
istic
(C
14)
1
5 -
20
Tra
ce
Myr
isto
leic
(C
14:1
)
Pal
miti
c (C
16)
5
.0 -
7.2
2
2 1
9 -
20
Sm
all
qu
antit
y 1
2 1
3-1
7 6
to
9 9
.3
7.8
Pal
mito
leic
(C
16:1
) 2
3 -
5.1
Hep
tade
cano
ic (
C17
:0)
Ste
aric
(C
18)
2
.0 -
6.5
2
3
3
3 t
o 5
7.4
2
.96
Ole
ic (
C18
:1)
11.
5 -
60.0
1
4.7
- 37
.2
60
22
- 26
25
67
-72
10
to 1
2 6
5.7
16.
77
Lino
leic
(C
18:2
) 2
5 -
63.1
5
1.5
- 73
.5
12
46
- 50
6
0 1
0 to
12
1 t
o 3
23.
08
Lino
leni
c (C
18:3
) 2
.9 -
12.
1 T
race
- 0
.3
Tra
ce
3
1.2
Ara
chid
ic (
C20
) 0
.3 -
1
2.5
Eic
osen
oic
(C20
:1)
1
1.99
Eic
osad
ieno
ic (
C20
:2)
Beh
enic
(C
22)
8
.6
Eru
cic
(C22
:1)
2
.8
Doc
osad
ieno
ic (
C22
:2)
Doc
osah
exae
noic
(C
22:6
)
Lign
ocer
ic (
C24
)
Tra
ce
Ara
chid
onic
(C
20:4
n6)
Ara
chid
ontr
ieno
ic
Oth
ers
3
.4
Ole
ic/L
inol
eic
90
-93
Sat
urat
ed, G
ener
al
12
- 13
.5
CIR Panel Book Page 30
22
Tab
le 3
. F
atty
aci
d co
mpo
sitio
n (c
ontin
ued.
)
Fat
ty A
cids
Coc
oa
See
d B
utte
r3 C
ohun
e O
il3 C
ranb
erry
S
eed
Oil73
C
ucum
ber
Oil74
Cup
uacu
S
eed
But
ter75
G
rape
S
eed
Oil3
Lins
eed
Oil3
Ma
ngo
See
d O
il3 **
Ma
rula
O
il76
Mea
dow
foam
S
eed
Oil3
Cap
roic
(C
6)
Cap
rylic
(C
8)
7.5
Cap
ric (
C10
) 6
.5
Laur
ic (
C12
)
46.
5
Myr
istic
(C
14)
1
6
T
race
Myr
isto
leic
(C
14:1
) P
alm
itic
(C16
) 2
4-2
9 9
.5
4.0
- 6
9
.0 -
13
7.2
7
-9.5
5
.5
5.0
-8
9 t
o 12
Pal
mito
leic
(C
16:1
) 0
.1
0.0
5 -
0.15
Hep
tade
cano
ic (
C17
:0)
0.2
Ste
aric
(C
18)
34
-36
3
6.0
- 9
3
0.8
3.5
-5.5
3
.5
33
-48
5 t
o 8
Ole
ic (
C18
:1)
30
-40
10
20
- 24
1
4 -
20
43.
9 1
4-4
4 1
9.1
35
-50
70
- 78
Lino
leic
(C
18:2
) 2
.4
1 3
2 -
37
60
- 68
4
.6
46
-74
15.
3 4
.0-8
4
.0 -
7.0
Lino
leni
c (C
18:3
) 3
0 -
35
< 1
T
race
5
7 0
.1 -
0.6
Ara
chid
ic (
C20
) 1
1 1
.0-7
0
.3 -
0.7
Eic
osen
oic
(C20
:1)
0.1
- 0
.5
52
- 77
Eic
osad
ieno
ic (
C20
:2)
Beh
enic
(C
22)
Eru
cic
(C22
:1)
0.1
- 0
.5
8.0
- 2
9
Doc
osad
ieno
ic (
C22
:2)
7.0
- 2
0
Doc
osah
exae
noic
(C
22:6
) Li
gnoc
eric
(C
24)
Ara
chid
onic
(C
20:4
n6)
Ara
chid
ontr
ieno
ic
Oth
ers
Ole
ic/L
inol
eic
Sat
urat
ed, G
ener
al
**A
s M
an
go K
ern
el F
at
CIR Panel Book Page 31
23
Tab
le 3
. F
atty
aci
d co
mpo
sitio
n (c
ontin
ued.
)
Fat
ty A
cids
M
urum
uru
See
d B
utte
r77
Pea
ch
Ker
nel
Oil78
P
erill
a O
il3 Q
uino
a S
eed
Oil79
R
amtil
/Nig
er
Oil3
Ric
e G
erm
O
il11
Stra
wbe
rry
See
d O
il80
***
Wat
erm
elon
S
eed
Oil81
W
heat
Ger
m
Oil13
,27
Bao
bab
Oil82
,83
Cap
roic
(C
6)
Cap
rylic
(C
8)
1.8
5
Cap
ric (
C10
) 1
.85
Laur
ic (
C12
) 4
7.46
Myr
istic
(C
14)
26
0.2
6.9
2
Myr
isto
leic
(C
14:1
)
Pal
miti
c (C
16)
6.2
8 2
.0 -
7
9
.9 -
11
5.0
-13
9.2
8
8.0
- 1
3.0
1
1.0
- 16
1
8-3
0
Pal
mito
leic
(C
16:1
) 0
.1
4.4
1 <
1.0
1
Hep
tade
cano
ic (
C17
:0)
Ste
aric
(C
18)
2.6
5 0
.5 -
3.5
0.7
- 0
.8
2.0
-11
7.9
1
8.0
- 1
2.0
1.0
- 6
2
-8
Ole
ic (
C18
:1)
12.
56
55
- 70
1
4-2
3 2
2 -
24.5
6
.0-4
0 1
7.81
1
6.5
- 19
.5
15.
0 -
30.0
8
.0 -
30
30
-40
Lino
leic
(C
18:2
) 2
.87
22
- 33
1
6 5
0.2
- 56
4
5-7
7 1
6.22
2
8.5
- 41
.5
55.
0 -
65.0
4
4 -
65
24
-34
Lino
leni
c (C
18:3
) <
1
63
-70
5.4
- 7
1
5.56
3
3.5
- 36
.5
< 1
.0
4.0
- 1
0 1
-3
Ara
chid
ic (
C20
) 0
.7
3.0
8 <
1.0
Eic
osen
oic
(C20
:1)
<
1.0
Eic
osad
ieno
ic (
C20
:2)
Beh
enic
(C
22)
<
1.0
Eru
cic
(C22
:1)
Doc
osad
ieno
ic (
C22
:2)
Doc
osah
exae
noic
(C
22:6
)
< 2
.0
Lign
ocer
ic (
C24
) 2
ma
x
Ara
chid
onic
(C
20:4
n6)
5
.48
Ara
chid
ontr
ieno
ic
5.2
1
Oth
ers
5
.5 -
8.5
<
1.0
0 -
1.2
C20
-22
S
atu
rate
d a
cid
s
Ole
ic/L
inol
eic
Sat
urat
ed, G
ener
al
6.0
-12
***R
epor
ted
as
Fra
garia
An
ana
ssa
(Str
aw
ber
ry)
Se
ed O
il.
CIR Panel Book Page 32
24
Tab
le 3
. F
atty
aci
d co
mpo
sitio
n (c
ontin
ued.
)
Fat
ty A
cids
R
ice
Bra
n O
il84
Che
rry
Ker
nel
Oil85
,86
Arg
an
Oil87
,88
Bor
age
Oil89
,90
Cam
ellia
O
leife
ra
See
d O
il91,9
2 P
apay
a S
eed
Oil93
,94
Lim
e S
eed
Oil95
,96
Ora
nge
See
d O
il97,9
8 G
rape
frui
t S
eed
Oil99
,100
Pum
pki
n S
eed
Oil10
1,10
2
Cap
roic
(C
6)
Cap
rylic
(C
8)
Cap
ric (
C10
)
Laur
ic (
C12
) 1
.5
Myr
istic
(C
14)
1 1
Myr
isto
leic
(C
14:1
)
Pal
miti
c (C
16)
14
4-1
0 1
0-1
5 9
-13
6.1
-15
8-1
8 2
0-3
0 1
4-2
2 1
8-3
0 1
0-1
6
Pal
mito
leic
(C
16:1
) 2
Hep
tade
cano
ic (
C17
:0)
Ste
aric
(C
18)
2 1
-4
5-6
.5
3-5
0
.8-2
2
-6
3-8
2
-6
2-8
3
-7
Ole
ic (
C18
:1)
45
23
-55
45
-55
10
-22
72
-87
60
-77
20
-38
26
-35
20
-38
18
-38
Lino
leic
(C
18:2
) 3
4 3
0-5
5 2
8-3
6 3
3-4
6 5
.3-1
4.3
3
-25
30
-45
35
-45
30
-48
40
-62
Lino
leni
c (C
18:3
) 1
13
18
-25
0.8
5
-15
2-6
2
-6
1
Ara
chid
ic (
C20
) 2
2 0
.5
Eic
osen
oic
(C20
:1)
2-6
2
Eic
osad
ieno
ic (
C20
:2)
Beh
enic
(C
22)
Eru
cic
(C22
:1)
1-3
.5
Doc
osad
ieno
ic (
C22
:2)
Doc
osah
exae
noic
(C
22:6
)
Lign
ocer
ic (
C24
)
Ara
chid
onic
(C
20:4
n6)
Ara
chid
ontr
ieno
ic
Oth
ers
Ele
oste
aric
(C
18:3
con
j) =
1
0%
α-L
inol
enic
(C
1 8:3
) =
0
.4%
; γ-L
inol
enic
=
1-3
.5%
α-L
inol
enic
(C
1 8:3
) =
2
%;
Ole
ic/L
inol
eic
Sat
urat
ed, G
ener
al
CIR Panel Book Page 33
25
Tab
le 3
. F
atty
aci
d co
mpo
sitio
n (c
ontin
ued.
)
Fat
ty A
cids
Cra
nber
ry
See
d O
il103,
104
Eve
ning
P
rimro
se
Oil10
5,10
6 P
lum
O
il107,
108
Bla
ckcu
rran
t S
eed
Oil10
9,11
0 R
ed R
aspb
erry
S
eed
Oil11
1,11
2 M
orin
ga
Oil11
3,11
4
Cap
roic
(C
6)
Cap
rylic
(C
8)
Cap
ric (
C10
) La
uric
(C
12)
Myr
istic
(C
14)
Myr
isto
leic
(C
14:1
) P
alm
itic
(C16
) 5
-5.4
4
-10
4-9
6
-10
2-2
.3
5-9
5-9P
alm
itole
ic (
C16
:1)
1 1
.5-3
Hep
tade
cano
ic (
C17
:0)
Ste
aric
(C
18)
1 2
-4
3 1
-4
0.9
-1
3-8
Ole
ic (
C18
:1)
24
5-1
2 6
0-8
0 9
-16
10.
9-1
1 6
5-8
0
Lino
leic
(C
18:2
) 3
5 6
0-8
5 1
5-2
5 4
0-5
0 5
2.6
-53
1.5
-5
Lino
leni
c (C
18:3
) 1
31.
9-3
2 1
-1.5
Ara
chid
ic (
C20
) 1
2-5
Eic
osen
oic
(C20
:1)
3 2
.5-4
Eic
osad
ieno
ic (
C20
:2)
Beh
enic
(C
22)
1 8
Eru
cic
(C22
:1)
1 3
Doc
osad
ieno
ic (
C22
:2)
Doc
osah
exae
noic
(C
22:6
) Li
gnoc
eric
(C
24)
Ara
chid
onic
(C
20:4
n6)
Ara
chid
ontr
ieno
ic
Oth
ers
α-L
inol
enic
(C
18:3
) =
3
4-3
5%
α-L
inol
enic
(C
1 8:3
) =
1%
γ-L
inol
enic
= 7
-1
2%
α-L
inol
enic
(C
1 8:3
) =
11
-1
7%
γ-L
inol
enic
=
11-
14%
S
tea
ridon
ic
(18
:4)
= 2
-2
.5%
Ole
ic/L
inol
eic
Sat
urat
ed, G
ener
al
CIR Panel Book Page 34
26
T
able
4. C
hem
ical
pro
pert
ies.
Pro
pert
ies
and
Con
stitu
ents
C
anol
a O
il2 C
otto
nsee
d O
il2,3
Oliv
e O
il3 P
alm
Oil2,
3 P
alm
Ker
nel O
il2,3
Rap
esee
d O
il3
App
eara
nce
Ligh
t ye
lllo
w o
il D
ark
red
-bro
wn
oil
Alm
ost
colo
rless
to
yello
w,
gre
enis
h, o
r b
row
n in
col
or
Pa
le y
ello
w t
o d
eep
or
an
ge in
col
or
Nea
rly c
olo
rless
Spe
cific
gra
vity
0
.914
-0.9
18
0.9
21-0
.925
(4
0◦C
)
Ref
ract
ive
inde
x
1.4
65-1
.467
(4
0◦C)
1.4
69-1
.484
1
.453
-1.4
58 (
40◦C
)
Iod
ine
valu
e 1
10-1
26
90
-113
6
4-8
8; r
efin
ed 7
5-9
4 4
4-5
8 1
4-3
3 8
1-1
12
Sap
onifi
catio
n va
lue
178
-193
1
80-1
98
185
-212
; ref
ined
184
-1
86
195
-205
2
45-2
55
168
-192
Per
oxid
e va
lue
(meq
/kg)
1
0 m
ax
10
ma
x 2
0 m
ax
(ref
ined
) 1
0 m
ax
10
ma
x
Mel
ting
poin
t (◦C
) 2
5-5
0 2
5-3
0
Uns
apon
ifiab
le m
atte
r (%
) 1
.5 m
ax
1.5
ma
x 0
.6-1
.2; 1
.5 m
ax
refin
ed
0.2
-0.8
1
.5 m
ax
0.5
- 2
Fre
e fa
tty a
cids
(%
) 0
.05
ma
x (a
s ol
eic
aci
d)
0.1
ma
x (a
s ol
eic
aci
d)#
# 0
.6-1
.4; 0
.3 m
ax
refin
ed 0
.1 m
ax
(as
olei
c ac
id);
0
.09
(as
pa
lmiti
c a
cid
)
0.1
ma
x (a
s ol
eic
acid
);
0.0
7 m
ax
(as
lau
ric
aci
d)
1
Lead
(m
g/kg
) 0
.1 m
ax
0.1
ma
x 0
.1 m
ax
0.1
mg/
kg m
ax
Aci
d va
lue
Pro
pert
ies
and
Con
stitu
ents
H
ydro
gena
ted
Rap
esee
d O
il2 S
afflo
wer
Oil2
Soy
bean
Oil2,
3 S
unflo
wer
Oil2,
3 A
pric
ot O
il3
Av o
cado
Oil3
App
eara
nce
Wh
ite w
axy
sol
id
Ligh
t ye
llow
oil
Ligh
t a
mb
er o
il Li
ght
am
ber
oil
Spe
cific
gra
vity
0
.894
-0.8
99 (
60◦C
) 0
.923
0
.910
-0.9
16
Ref
ract
ive
inde
x
1.4
597
-1.4
745
(a
t 25◦C
) 1
.467
2-1
.47
22
1.4
61-1
.465
Iod
ine
valu
e 4
ma
x 1
35-1
50
120
.9-1
51.4
1
28-1
44
81
-123
7
1-9
5
Sap
onifi
catio
n va
lue
188
-194
1
91
177
-198
Per
oxid
e va
lue
(meq
/kg)
2
.0 m
ax
10
ma
x 1
0 m
ax
10
ma
x
Mel
ting
poin
t (◦C
) 0
Uns
apon
ifiab
le m
atte
r (%
) 1
.5 m
ax
0.3
-0.6
0
.3-0
.5
Fre
e fa
tty a
cids
(%
) 2
.0 m
ax
(as
olei
c ac
id)
0.1
ma
x (a
s ol
eic
acid
) 0
.05
-0.7
0
.1 m
ax
(as
olei
c ac
id)
Lead
(m
g/kg
) 0
.1 m
ax
0.1
ma
x 0
.1 m
ax
0.1
ma
x
Aci
d va
lue
CIR Panel Book Page 35
27
T
able
4. C
hem
ical
pro
pert
ies
(con
tinue
d).
Pro
pert
ies
and
Con
stitu
ents
B
abas
su O
il3 C
o coa
Oil3
Cra
nber
ry S
eed
Oil3,
73
Gra
pe S
eed
Oil3
Lins
eed
Oil3
Ma
ngo
Oil3
App
eara
nce
Ligh
t gr
een
P
ale
ye
llo t
o iv
ory
crea
m c
olor
Spe
cific
gra
vity
0
.916
-0.9
18 (
15◦C
) 0
.950
-0.9
98
0.9
23
0.9
1-0
.93
0.9
27-0
.931
(2
0◦C
) 0
.91
Ref
ract
ive
inde
x
1.4
49-1
.451
(4
0◦C)
1.4
53-1
.458
1
.470
-1.4
76
1.4
786
-1.4
815
1
.456
Iod
ine
valu
e 1
4-1
8 3
5-4
0 1
50.1
1
25-1
43
170
-204
3
2-9
3
Sap
onifi
catio
n va
lue
247
-251
1
90-2
00
176
-206
1
89-1
96
190
-195
Per
oxid
e va
lue
(meq
/kg)
<
15
Mel
ting
poin
t (◦C
) 3
3.5
0 3
4-4
3
Uns
apon
ifiab
le m
atte
r (%
) 0
.5-1
.5
0.8
-2.9
Fre
e fa
tty a
cids
(%
) 5
Lead
(m
g/kg
)
Aci
d va
lue
Pro
pert
ies
and
Con
stitu
ents
M
urum
uru
But
ter
3,77
P
each
Ker
nel O
il3,78
R
amtil
/Nig
er O
il3
Stra
wbe
rry
See
d O
il3,80
W
ater
mel
on S
eed
Oil3,
81
Bao
bab
Oil82
,83
App
eara
nce
Pa
le b
row
n w
axy
sol
id
at
room
tem
per
atu
re
Pa
le y
ello
w (
refin
ed)
Pa
le y
ello
w w
ith a
b
luis
h ti
nt
Ligh
t go
lden
P
ale
to
gold
en y
ello
w
liqui
d P
ale
ye
llow
Spe
cific
gra
vity
0
.890
-0.9
10 (
25◦C
) 0
.910
-0.9
20 (
20◦C
) re
fined
0
.910
-0.9
28
0.9
5 0
.893
0-0
.91
66
Ref
ract
ive
inde
x
1.4
67-1
.471
1
.466
8
Iodi
ne v
alue
1
5 m
ax
90
-115
(re
fined
) 1
26-1
39
113
-123
6
5-9
5
Sap
onifi
catio
n va
lue
270
-350
1
80-1
95
193
-195
1
90-2
10
Per
oxid
e va
lue
(meq
/kg)
2
0.0
ma
x 5
.0 m
ax
(ref
ined
) <
15
< 5
.0
5.0
-10
Mel
ting
poin
t (◦C
) 2
5- 3
7
Uns
apon
ifiab
le m
atte
r (%
) 0
.5-1
Fre
e fa
tty a
cids
(%
) 1
2.56
(a
s ol
eic
aci
d)
0.4
-3
< 5
.0 (
as
olei
c ac
id)
2.0
ma
x (a
s ol
eic
aci
d)
Lead
(m
g/kg
)
Aci
d va
lue
CIR Panel Book Page 36
28
Tab
le 4
. Che
mic
al p
rope
rtie
s (c
ontin
ued)
.
Pro
pert
ies
and
Con
stitu
ents
R
ice
Bra
n O
il84,1
15
Che
rry
Ker
nel
Oil85
,86
Cor
n O
il65
,66
Arg
an O
il87,8
8 B
orag
e O
il89,9
0 C
amel
lia O
leife
ra
See
d O
il91,9
2
App
eara
nce
Ligh
t go
lden
ye
llow
C
lea
r lig
ht
yello
w
Cle
ar,
brig
ht
gold
en
yello
w
Yel
low
C
lea
r, p
ale
ye
llow
-go
lden
C
lea
r, p
ale
ye
llow
or
“wa
ter
wh
ite”
Spe
cific
gra
vity
0
.916
-0.9
22 (
15.
5◦C)
0.9
05-0
.925
(2
0◦C)
0.9
20-0
.928
(1
5.5◦C
) 0
.908
-0.9
18 (
20◦C
) 0
.918
-0.9
28 (
20◦C
)
Ref
ract
ive
inde
x
1.4
70-1
.473
(2
0◦C)
1.4
63-1
.480
(2
0◦C)
1.4
72-1
.476
(2
0◦C)
1.4
74-1
.479
(2
0◦C)
Iod
ine
valu
e 9
2-1
15
90
-115
1
03-1
28
95
130
-155
8
0-9
4
Sap
onifi
catio
n va
lue
180
-195
1
05-1
35
185
-195
1
84-1
94
188
-196
Per
oxid
e va
lue
(meq
/kg)
1
0.0
ma
x 1
0.0
ma
x 1
0.0
ma
x 1
0.0
ma
x 1
0.0
ma
x 1
0.0
ma
x
Mel
ting
poin
t (◦C
)
Uns
apon
ifiab
le m
atte
r (%
) 1
.5 m
ax
Fre
e fa
tty a
cids
(%
) 1
.0 (
as
olei
c a
cid
) 0
.5%
ma
x
Lead
(m
g/kg
) A
cid
valu
e 1
.0 m
ax
0.2
ma
x 3
-4
1.0
ma
x 1
.0 m
ax
Pro
pert
ies
and
Con
stitu
ents
P
apay
a S
eed
Oil
93,9
4 Li
me
See
d O
il95,9
6 O
rang
e S
eed
Oil97
,98
Gra
pefr
uit S
eed
Oil99
,100
Pum
pki
n S
eed
Oil10
1,10
2 C
ranb
erry
See
d O
il103,
104
App
eara
nce
Pa
le y
ello
w
Cle
ar
yello
w
Cle
ar,
ligh
t ye
llow
C
lea
r ye
llow
D
ark
gre
en
Spe
cific
gra
vity
0
.910
-0.9
20 (
20◦C
)
Ref
ract
ive
inde
x
1.4
66-1
.475
(2
0◦C)
Iod
ine
valu
e 6
5-1
00
90
-110
8
0-1
25
110
-330
1
40-1
80
Sap
onifi
catio
n va
lue
185
-200
1
74-1
97
170
-200
Per
oxid
e va
lue
(meq
/kg)
1
0.0
ma
x 5
.0 m
ax
5-1
0 5
-10
5.0
ma
x 5
.0 m
ax
Mel
ting
poin
t (◦C
)
Uns
apon
ifiab
le m
atte
r (%
) 1
.5
Fre
e fa
tty a
cids
(%
) 0
.8-3
0
.5 (
as
olei
c a
cid
) 1
.5 (
as
olei
c)
1.0
(a
s ol
eic
aci
d)
Lead
(m
g/kg
) A
cid
valu
e 1
.0 m
ax
0.8
ma
x 1
.0 m
ax
2.0
ma
x
CIR Panel Book Page 37
29
Tab
le 4
. Che
mic
al p
rope
rtie
s (c
ontin
ued)
.
Pro
pert
ies
and
Con
stitu
ents
E
veni
ng P
rimro
se
Oil10
5,10
6 P
lum
Oil10
7,10
8 B
lack
curr
ant S
eed
Oil10
9,11
0 R
ed R
aspb
erry
S
eed
Oil11
1,11
2 M
orin
ga O
il11
3,11
4
App
eara
nce
Ligh
t ye
llow
Spe
cific
gra
vity
0
.920
-0.9
30 (
20◦C
) 0
.908
(2
0◦C
)
Ref
ract
ive
inde
x
1.4
75-1
.480
(2
0◦C)
Iod
ine
valu
e 1
45-1
65
90
-108
1
45-1
85
175
-195
Sap
onifi
catio
n va
lue
180
-195
1
80-2
00
192
Per
oxid
e va
lue
(meq
/kg)
1
0.0
ma
x 1
0.0
ma
x 1
-10
5.0
ma
x 1
0.0
Mel
ting
poin
t (◦C
)
Uns
apon
ifiab
le m
atte
r (%
)
Fre
e fa
tty a
cids
(%
) 2
.0 m
ax
(as
olei
c a
cid
) 0
.2
1.5
ma
x (a
s ol
eic
aci
d)
2.0
ma
x (a
s ol
eic
acid
)
Lead
(m
g/kg
) A
cid
valu
e 1
-2
3
CIR Panel Book Page 38
30
Tab
le 5
a. F
requ
ency
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
. N
R =
Not
rep
orte
d t
o V
CR
P o
r C
ounc
il. N
S =
Not
yet
su
rve
yed
.
No.
of
Use
s (2
010)
C
onc.
of
Use
(2
010)
(%)
No.
of
Use
s (2
010)
C
onc.
of
Use
(2
010)
(%)
No.
of
Use
s (2
010)
C
onc.
of
Use
(2
010)
(%)
No.
of
Use
s (2
010)
Con
c. o
f U
se (
2010
) (%
)
No.
of
Use
s (2
010)
C
onc.
of
Use
(2
010)
(%)
No.
of
Use
s (2
010)
C
onc.
of
Use
(2
010)
(%)
Veg
etab
le (
Olu
s) O
il
Hyd
roge
nate
d V
eget
able
Oil
Bra
ssic
a C
ampe
stris
(R
apes
eed)
See
d O
il H
ydro
gena
ted
Rap
esee
d O
il C
anol
a O
il C
anol
a O
il U
nsap
onifi
able
s
Tot
als
165
0.00
05-3
1 45
7 0.
0004
-60
27
0.00
7-17
1
0.3-
4 13
2 0.
0002
-73
NR
0.
001
Dur
atio
n of
Use
Le
ave
-On
135
0
.000
5-1
1 4
39
0.0
005
-60
23
0.0
07-1
7 N
R
0.3
-4
112
0
.002
-73
NR
N
R
Rin
se O
ff
30
0.0
02-3
1 1
8 0
.000
4-8
4
0.1
-1
1 N
R
20
0.0
2-3
3 N
R
0.0
001
Exp
osur
e T
ype
Eye
Are
a 1
1 0
.01
-11
102
0
.008
-49
2 N
R
NR
2
3 0
.002
-0.0
3 N
R
NR
P
oss
ible
Ing
est
ion
74
0.0
3-1
1 2
16
0.8
-60
1 9
NR
N
R
62
0.3
-70
NR
N
R
Inha
latio
n 1
0.0
005
-0.0
2 1
3 N
R
NR
N
R
NR
1
0.0
002
-17
NR
N
R
De
rma
l Co
nta
ct
143
0
.000
5-3
1 4
50
0.0
05-6
0 2
7 0
.007
-17
1 0
.3-4
1
13
0.0
002
-73
NR
N
R
De
odo
ran
t (U
nde
rarm
) N
R
---
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
Ha
ir -
No
n-C
olor
ing
2 0
.02
-2
2 0
.000
5-0
.09
NR
0
.1
NR
N
R
19
0.0
06-2
4 N
R
0.0
01
Ha
ir -
Co
lorin
g 1
8 --
- N
R
0.0
004
-1
NR
N
R
NR
N
R
NR
N
R
NR
N
R
Nai
l 1
2 1
0.2
N
R
NR
N
R
NR
N
R
5 N
R
NR
M
ucou
s M
em
bra
ne
1 0
.03
-2
2 2
-4
1 N
R
NR
N
R
2 0
.02
-1
NR
N
R
Ba
th P
rodu
cts
2 0
.002
-0.0
2 N
R
0.5
N
R
NR
N
R
NR
1
1-3
3 N
R
NR
B
aby
Pro
duct
s 1
---
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
H
ydro
gena
ted
Can
ola
Oil
Pal
m K
erne
l Aci
d E
laei
s O
leife
ra K
erne
l Oil
Pal
m A
cid
Pot
assi
um P
alm
ate
Pot
assi
um P
alm
Ker
nela
te
Tot
als
3 N
R
72
0.2-
12
5 N
R
33
1-17
5
0.3-
3 7
0.3-
30
Dur
atio
n of
Use
Le
ave
-On
2 N
R
3 N
R
NR
N
R
1 N
R
NR
N
R
NR
N
R
Rin
se-O
ff
1 N
R
69
0.2
-12
5 N
R
32
1-1
7 5
0.3
-3
7 0
.3-3
0 E
xpos
ure
Typ
e
Eye
Are
a N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
P
oss
ible
Ing
est
ion
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
Inha
latio
n N
R
NR
N
R
NR
N
R
NR
1
NR
N
R
NR
N
R
NR
D
erm
al C
ont
act
3
NR
7
1 0
.2-1
2 N
R
NR
3
3 1
-17
5 0
.3-3
7
0.3
-30
De
odo
ran
t (U
nde
rarm
) N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
H
air
- N
on
-Col
orin
g N
R
NR
1
NR
2
NR
N
R
NR
N
R
NR
N
R
NR
H
air
- C
olo
ring
NR
N
R
NR
N
R
3 N
R
NR
N
R
NR
N
R
NR
N
R
Nai
l N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
M
ucou
s M
em
bra
ne
NR
N
R
64
0.2
-3
NR
N
R
31
1-4
2
0.3
-3
1 0
.3-3
0 B
ath
Pro
duct
s N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
B
aby
Pro
duct
s N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
CIR Panel Book Page 39
31
Tab
le 5
a. F
requ
ency
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
. (co
ntin
ued)
NR
= N
ot r
epor
ted
to
VC
RP
or
Cou
ncil.
NS
= N
ot y
et s
urv
eye
d.
N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
)
Sod
ium
Pal
mat
e S
odiu
m P
alm
Ker
nela
te
Gly
cine
Soj
a (S
oybe
an)
Oil
Gly
cine
Soj
a (S
oybe
an)
Oil
Uns
apon
ifiab
les
Hyd
roge
nate
d S
oybe
an O
il H
elia
nthu
s A
nnuu
s (S
unflo
wer
) S
eed
Oil
Tot
als
212
3-68
19
4 12
-44
912
0.00
02-9
5 12
0.
0001
-0.2
36
0.
001-
42
1414
0.
0000
07-9
6 D
urat
ion
of U
se
Le
ave
-On
7 N
R
10
NR
7
18
0.0
005
-95
12
0.0
001
-0.2
3
3 0
.001
-39
105
4 0
.000
2-9
6 R
inse
Off
205
3
-68
184
1
2-4
4 1
94
0.0
002
-95
NR
N
R
3 0
.05
-42
360
0
.000
007
-92
Exp
osur
e T
ype
Eye
Are
a
NR
N
R
NR
N
R
53
0.0
4-2
N
R
NR
4
0.0
3-7
6
4 0
.000
5-1
9 P
ossi
ble
Inge
stio
n
NR
N
R
NR
N
R
103
0
.6-4
N
R
NR
3
0.1
-39
260
0
.08
-41
Inh
ala
tion
1 N
R
1 N
R
6 0
.03
-0.5
N
R
NR
N
R
NR
3
0.0
002
-85
Der
ma
l Con
tact
2
12
3-6
8 1
94
12
-44
800
0
.000
5-9
3 1
2 0
.000
1-0
.2
34
0.0
1-3
9 7
07
0.0
002
-96
Deo
dor
an
t (U
nder
arm
) N
R
NR
N
R
NR
N
R
0.0
1-0
.5
NR
N
R
NR
N
R
1 0
.000
3-4
H
air
- N
on-C
olor
ing
NR
N
R
NR
N
R
97
0.0
002
-95
NR
N
R
1 0
.1
179
0
.000
007
-92
Ha
ir -
Col
orin
g N
R
NR
N
R
NR
5
NR
N
R
NR
N
R
NR
8
5 0
.03
-35
Na
il N
R
NR
N
R
NR
6
0.0
2-9
5 N
R
NR
N
R
0.0
01-2
5 8
0.0
5-3
0 M
ucou
s M
emb
ran
e 1
89
3-6
8 1
73
16
-44
70
0.0
1-5
2 N
R
NR
N
R
0.0
5-6
5
2 0
.000
3-4
B
ath
Pro
duct
s 1
NR
3
NR
1
9 0
.1-7
8 N
R
NR
N
R
5-4
2 1
1 0
.005
-75
Bab
y P
rod
uct
s 3
NR
4
NR
2
1 2
NR
N
R
NR
N
R
18
0.2
H
el. A
nnuu
s (S
unflo
wer
) S
eed
Oil
Uns
apon
ifiab
les
Hyd
roge
nate
d S
unflo
wer
S
eed
Oil
Ole
a E
urop
ea (
Oliv
e) F
ruit
Oil
Hyd
roge
nate
d O
live
Oil
Hyd
roge
nate
d O
live
Oil
Uns
apon
ifiab
les
Ole
a E
urop
aea
(Oliv
e) O
il U
nsap
onifi
able
s
Tot
als
10
0.00
5-2
NR
6-
35
915
0.00
05-1
00
50
0.00
05-1
2 2
0.05
-5
77
0.00
01-3
Dur
atio
n of
Use
Le
ave
-On
10
0.0
05-2
N
R
6-3
5 6
17
0.0
01-1
00
36
0.1
-12
2 0
.05
-5
68
0.0
001
-3
Rin
se-O
ff
NR
0
.002
N
R
15
-35
298
0
.000
5-9
4 1
4 0
.000
5-0
.1
NR
N
R
9 0
.04
-0.3
Exp
osur
e T
ype
Eye
Are
a
2 0
.02
NR
7
26
0.0
04-1
7 1
3 0
.1-3
N
R
0.3
-2
12
0.0
2-0
.4
Pos
sib
le In
gest
ion
N
R
NR
N
R
6 2
6 0
.7-2
6 7
0.1
-12
NR
N
R
1 0
.08
Inh
ala
tion
NR
N
R
NR
N
R
6 0
.2-5
N
R
NR
N
R
NR
N
R
3
Der
ma
l Con
tact
1
0 0
.005
-2
NR
6
-35
711
0
.000
5-1
00
34
0.0
005
-12
2 0
.05
-5
67
0.0
001
-3
Deo
dor
an
t (U
nder
arm
) N
R
NR
N
R
NR
3
0.0
2-0
.1
NR
N
R
NR
N
R
NR
N
R
Ha
ir -
Non
-Col
orin
g N
R
NR
N
R
NR
1
90
0.0
06-9
4 1
1 0
.01
-0.1
N
R
NR
6
0.0
2-0
.3
Ha
ir -
Col
orin
g N
R
NR
N
R
15
-35
NR
0
.2-0
.5
NR
N
R
NR
N
R
NR
N
R
Na
il N
R
NR
N
R
NR
5
1-4
0 N
R
NR
N
R
NR
N
R
NR
M
ucou
s M
emb
ran
e N
R
0.0
02
NR
N
R
121
0
.000
5-3
1
0.0
005
NR
N
R
4 N
R
Ba
th P
rodu
cts
NR
N
R
NR
N
R
14
0.9
-17
NR
N
R
NR
N
R
NR
N
R
Bab
y P
rod
uct
s N
R
NR
N
R
NR
9
0.2
N
R
0.4
N
R
NR
N
R
0.0
4
CIR Panel Book Page 40
32
Tab
le 5
a. F
requ
ency
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
. (co
ntin
ued)
NR
= N
ot r
epor
ted
to
VC
RP
or
Cou
ncil.
NS
= N
ot y
et s
urv
eye
d.
N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
)
Pot
assi
um O
livat
e S
odiu
m O
livat
e A
ctin
idia
Chi
nens
is (
Kiw
i) S
eed
Oil
Ada
nson
ia D
igita
ta O
il [B
aoba
b]
Arg
ania
Spi
nosa
Ker
nel O
il [A
rgan
] A
stro
cary
um M
urum
uru
See
d B
utte
r [M
urum
ura]
Tot
als
3 N
R
16
4-18
7
0.1
6 0.
01
100
0.00
1-10
19
2 0.
001-
7
Dur
atio
n of
Use
Le
ave
-On
NR
N
R
5 N
R
5 N
R
4 0
.01
87
0.0
01-1
0 1
71
0.0
01-7
Rin
se O
ff
3 N
R
11
4-1
8 2
0.1
2
NR
1
3 0
.001
-2
21
0.0
01-0
.2
Exp
osur
e T
ype
Eye
Are
a
NR
N
R
NR
N
R
NR
N
R
NR
N
R
11
0.1
-1
21
0.0
6-0
.5
Pos
sib
le In
gest
ion
N
R
NR
N
R
NR
1
NR
N
R
0.0
1 9
0.1
-1
22
1-7
In
ha
latio
n N
R
NR
N
R
NR
1
NR
N
R
NR
N
R
0.0
1 N
R
NR
D
erm
al C
onta
ct
3 N
R
16
4-1
8 5
NR
5
0.0
1 8
8 0
.001
-10
178
0
.001
-7
Deo
dor
an
t (U
nder
arm
) N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
0.0
01
NR
N
R
Ha
ir -
Non
-Col
orin
g N
R
NR
N
R
NR
2
0.1
1
NR
8
0.0
1-1
1
1 0
.001
-0.2
H
air
- C
olor
ing
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
0
.07
-0.1
3
NR
N
ail
NR
N
R
NR
N
R
NR
N
R
NR
N
R
2 0
.001
-0..1
N
R
NR
M
ucou
s M
emb
ran
e 1
NR
9
4-1
8 N
R
NR
N
R
NR
2
0.0
01-2
3
NR
B
ath
Pro
duct
s N
R
NR
N
R
NR
N
R
NR
N
R
NR
1
0.0
5 N
R
NR
B
aby
Pro
du
cts
NR
N
R
1 N
R
NR
N
R
1 N
R
NR
N
R
NR
N
R
S
odiu
m A
stro
cary
um
Mur
umur
uate
A
vena
Sat
iva
(Oat
) K
erne
l O
il B
orag
o O
ffici
nalis
See
d O
il [B
orag
e]
Bra
ssic
a O
lera
cea
Italic
a (B
rocc
oli)
See
d O
il C
amel
ina
Sat
iva
See
d O
il [F
alse
Fla
x]
Cam
ellia
Jap
onic
a S
eed
Oil
Tot
als
NR
0.
002-
0.00
5 43
0.
01-3
18
0 0.
001-
1 N
R
0.00
1-3
76
0.00
2-1
NR
0.
01-0
.2
Dur
atio
n of
Use
Le
ave
-On
NR
0
.002
3
7 0
.1-3
1
60
0.0
01-1
N
R
3 6
1 0
.002
-1
NR
0
.01
-0.2
Rin
se-O
ff
NR
0
.002
-0.0
05
6 0
.001
-0.1
2
0 0
.001
-0.0
1 N
R
0.0
01-0
.5
15
1 N
R
0.1
Exp
osur
e T
ype
Eye
Are
a
NR
N
R
NR
0
.2
7 0
.001
-0.5
N
R
NR
N
R
0.0
5 N
R
0.0
1 P
ossi
ble
Inge
stio
n
NR
N
R
NR
2
NR
0
.01
NR
N
R
34
0.0
5-0
.5
NR
0
.1
Inh
ala
tion
NR
N
R
NR
N
R
3 0
.1
NR
N
R
NR
N
R
NR
N
R
Der
ma
l Con
tact
N
R
0.0
02-0
.005
4
1 0
.001
-3
168
0
.001
-1
NR
N
R
47
0.0
02-1
N
R
0.0
1-0
.2
Deo
dor
an
t (U
nder
arm
) N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
0.0
1
Ha
ir -
Non
-Col
orin
g N
R
NR
2
0.1
1
0 N
R
NR
N
R
29
1 N
R
0.1
H
air
- C
olor
ing
NR
N
R
NR
N
R
NR
N
R
NR
0
.001
-3
NR
N
R
NR
N
R
Na
il N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
M
ucou
s M
emb
ran
e N
R
0.0
02
2 0
.01
-0.1
4
0.0
01-0
.01
NR
N
R
NR
N
R
NR
0
.1
Ba
th P
rodu
cts
NR
N
R
1 N
R
1 N
R
NR
N
R
NR
N
R
NR
N
R
Bab
y P
rod
uct
s N
R
NR
6
0.1
3
NR
N
R
NR
N
R
NR
N
R
NR
CIR Panel Book Page 41
33
Tab
le 5
a. F
requ
ency
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
. (co
ntin
ued)
NR
= N
ot r
epor
ted
to
VC
RP
or
Cou
ncil.
NS
= N
ot y
et s
urv
eye
d.
N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
)
Cam
ellia
Ole
ifera
See
d O
il [T
ea S
eed]
H
ydro
gena
ted
Cam
ellia
O
leife
ra S
eed
Oil
Cam
ellia
Sin
ensi
s S
eed
Oil
Car
ica
Pap
aya
See
d O
il C
aryo
car
Bra
sile
nse
Fru
it O
il (P
equi
) C
heno
podi
um Q
uino
a S
eed
Oil
[Qui
noa]
Tot
als
25
0.00
3-3
1 N
R
12
0.1
NR
0.
1 31
0.
0005
-0.2
1
0.3
Dur
atio
n of
Use
Le
ave
-On
23
0.0
03-3
1
NR
8
0.1
N
R
0.1
2
9 0
.000
5-2
1
NR
Rin
se O
ff
2 0
.01
-0.1
N
R
NR
4
0.1
N
R
NR
2
NR
N
R
0.3
Exp
osur
e T
ype
Eye
Are
a
NR
2
NR
N
R
NR
N
R
NR
N
R
12
NR
N
R
NR
P
ossi
ble
Inge
stio
n
3 3
NR
N
R
1 0
.1
NR
N
R
12
0.2
N
R
NR
In
ha
latio
n N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
D
erm
al C
onta
ct
23
0.0
03-3
1
NR
1
0 0
.1
NR
0
.1
30
0.0
005
-0.2
N
R
NR
D
eod
ora
nt
(Und
era
rm)
NR
N
R
NR
N
R
NR
0
.1
NR
N
R
NR
N
R
NR
N
R
Ha
ir -
Non
-Col
orin
g 2
2 N
R
NR
2
0.1
N
R
NR
1
NR
1
NR
H
air
- C
olor
ing
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
0
.3
Na
il N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
M
ucou
s M
emb
ran
e N
R
0.0
1-0
.1
NR
N
R
2 0
.1
NR
N
R
NR
N
R
NR
N
R
Ba
th P
rodu
cts
NR
0
.05
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
Bab
y P
rod
uct
s N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
C
itrul
lus
Lana
tus
(Wat
erm
elon
) S
eed
Oil
Citr
us V
ulga
ris
(Wat
erm
elon
) S
eed
Oil
Citr
us G
rand
is (
Gra
pefr
uit)
S
eed
Oil
Citr
us P
arad
isi (
Gra
pefr
uit)
S
eed
Oil
Citr
us M
edic
a Li
mon
um
(Lem
on)
See
d O
il C
ucum
is S
ativ
us (
Cuc
umbe
r)
See
d O
il
Tot
als
1 2
1 N
R
NR
0.
1 6
NR
5
NR
6
NR
D
urat
ion
of U
se
Le
ave
-On
1 2
1 N
R
NR
0
.1
5 N
R
3 N
R
5 N
R
Rin
se-O
ff
NR
N
R
NR
N
R
NR
0
.1
1 N
R
2 N
R
1 N
R
Exp
osur
e T
ype
Eye
Are
a
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
1 N
R
Pos
sib
le In
gest
ion
N
R
NR
N
R
NR
N
R
0.1
N
R
NR
N
R
NR
N
R
NR
In
ha
latio
n N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
D
erm
al C
onta
ct
1 2
1 N
R
NR
0
.1
6 N
R
5 N
R
5 N
R
Deo
dor
an
t (U
nder
arm
) N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
H
air
- N
on-C
olor
ing
NR
N
R
NR
N
R
NR
0
.1
NR
N
R
NR
N
R
1 N
R
Ha
ir -
Col
orin
g N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
ail
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
Muc
ous
Mem
bra
ne
NR
N
R
NR
N
R
NR
0
.1
1 N
R
1 N
R
NR
N
R
Ba
th P
rodu
cts
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
Bab
y P
rod
uct
s N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
CIR Panel Book Page 42
34
Tab
le 5
a. F
requ
ency
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
. (co
ntin
ued)
NR
= N
ot r
epor
ted
to
VC
RP
or
Cou
ncil.
NS
= N
ot y
et s
urv
eye
d.
N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
)
Cuc
urbi
ta P
epo
(Pum
pkin
) S
eed
Oil
Eut
erpe
Ole
race
a F
ruit
Oil
[Aca
i] Ir
ving
ia G
abon
ensi
s K
erne
l B
utte
r [D
ika]
Li
mna
nthe
s A
lba
(Mea
dow
foam
) S
eed
Oil
Linu
m U
sita
tissi
mum
(L
inse
ed)
See
d O
il Li
nsee
d A
cid
Tot
als
18
0.00
3-0.
1 29
0.
0000
1-0.
5 10
9 0.
003-
0.4
316
0.00
2-74
10
2 0.
001-
10
3 N
R
Dur
atio
n of
Use
Le
ave
-On
17
0.0
03-0
.1
19
0.0
000
1-0
.5
109
0
.003
-0.4
2
25
0.0
02-7
4 5
2 0
.002
-10
3 N
R
Rin
se O
ff
1 N
R
10
0.0
5 N
R
NR
9
1 0
.01
-2
50
0.0
01-0
.4
NR
N
R
Exp
osur
e T
ype
Eye
Are
a
1 0
.003
2
0.5
2
NR
3
0 0
.1-2
0 3
0.0
1 N
R
NR
P
ossi
ble
Inge
stio
n
NR
N
R
1 0
.002
6
4 0
.003
-0.3
6
7 0
.6-2
6 N
R
0.0
1 N
R
NR
In
ha
latio
n 1
NR
1
NR
N
R
NR
1
0.1
-3
3 N
R
NR
N
R
Der
ma
l Con
tact
1
8 0
.003
-0.1
1
4 0
.000
01
-0.5
1
08
0.0
03-0
.4
211
0
.002
-74
58
0.0
03-4
3
NR
D
eod
ora
nt
(Und
era
rm)
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
0
.05
-0.1
N
R
NR
H
air
- N
on-C
olor
ing
1 N
R
15
NR
1
NR
4
7 0
.1-1
4
2 0
.001
-0.1
N
R
NR
H
air
- C
olor
ing
NR
N
R
NR
N
R
NR
N
R
46
0.2
-2
NR
N
R
NR
N
R
Na
il N
R
NR
N
R
NR
N
R
NR
N
R
0.5
2
0.0
02-0
.05
NR
N
R
Muc
ous
Mem
bra
ne
NR
N
R
3 N
R
NR
N
R
4 0
.001
-0.6
5
0.0
03-0
.4
NR
N
R
Ba
th P
rodu
cts
NR
N
R
NR
N
R
NR
N
R
2 0
.5-0
.9
1 0
.02
-0.2
N
R
NR
B
aby
Pro
du
cts
NR
N
R
NR
N
R
NR
N
R
1 N
R
2 N
R
1 N
R
M
angi
fera
Indi
ca (
Man
go)
See
d O
il M
angi
fera
Indi
ca (
Man
go)
See
d B
utte
r S
odiu
m M
ango
seed
ate
Mor
inga
Ole
ifera
See
d O
il [B
en]
Mor
inga
Pte
rygo
sper
ma
See
d O
il O
enot
hera
Bie
nnis
(E
veni
ng
Prim
rose
) O
il
Tot
als
72
0.00
3-6
175
0.00
05-3
1
NR
N
R
0.00
1 15
0.
003-
3 15
0 0.
0000
2-58
D
urat
ion
of U
se
Le
ave
-On
64
0.0
03-6
1
34
0.0
1-5
N
R
NR
N
R
0.0
01
13
0.0
04-3
1
13
0.0
000
2-5
8 R
inse
-Off
8 0
.05
-0.2
4
1 0
.000
5-0
.5
1 N
R
NR
N
R
2 0
.003
3
7 0
.002
-0.2
E
xpos
ure
Typ
e
Eye
Are
a
13
5 6
0.0
2 N
R
NR
N
R
NR
4
3 4
0.0
000
2-0
.5
Pos
sib
le In
gest
ion
7
0.0
3-6
2
5 1
-5
NR
N
R
NR
N
R
1 N
R
14
0.1
-15
Inh
ala
tion
1 N
R
2 0
.02
NR
N
R
NR
N
R
NR
N
R
2 N
R
Der
ma
l Con
tact
6
0 0
.003
-6
147
0
.000
5-5
1
NR
N
R
0.0
01
11
0.0
03-3
1
09
0.0
000
2-5
8 D
eod
ora
nt
(Und
era
rm)
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
0
.2
Ha
ir -
Non
-Col
orin
g 1
2 0
.05
-0.2
1
2 0
.02
-0.5
N
R
NR
N
R
NR
1
0.0
2 3
7 0
.05
-0.1
H
air
- C
olor
ing
NR
0
.05
16
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
ail
NR
N
R
NR
0
.5
NR
N
R
NR
N
R
NR
N
R
4 0
.001
-3
Muc
ous
Mem
bra
ne
2 0
.1
10
0.0
005
-0.5
1
NR
N
R
NR
N
R
0.0
03
4 0
.1-0
.2
Ba
th P
rodu
cts
NR
N
R
1 N
R
NR
N
R
NR
N
R
NR
N
R
2 0
.2
Bab
y P
rod
uct
s N
R
NR
3
NR
N
R
NR
N
R
NR
N
R
NR
3
NR
CIR Panel Book Page 43
35
Tab
le 5
a. F
requ
ency
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
. (co
ntin
ued)
NR
= N
ot r
epor
ted
to
VC
RP
or
Cou
ncil.
NS
= N
ot y
et s
urv
eye
d.
N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
)
Hyd
roge
nate
d E
veni
ng
Prim
rose
Oil
Org
ibny
a C
ohum
e S
eed
Oil
Orb
igny
a O
leife
ra S
eed
Oil
[Bab
assu
] S
odiu
m B
abas
suat
e P
erill
a O
cym
oide
s S
eed
Oil
[Per
illa]
H
ydro
gena
ted
Avo
cado
Oil
Tot
als
14
NR
1
NR
16
1 0.
0009
-27
NR
8
7 N
R
11
0.5
Dur
atio
n of
Use
Le
ave
-On
14
NR
N
R
NR
1
18
0.0
009
-4
NR
N
R
5 N
R
9 N
R
Rin
se O
ff
NR
N
R
1 N
R
43
0.0
1-2
7 N
R
8 2
NR
2
0.5
Exp
osur
e T
ype
Eye
Are
a
1 N
R
NR
N
R
7 0
.5-0
.6
NR
N
R
2 N
R
NR
N
R
Pos
sib
le In
gest
ion
N
R
NR
N
R
NR
5
7 0
.001
-2
NR
N
R
NR
N
R
2 N
R
Inh
ala
tion
NR
N
R
NR
N
R
5 0
.02
-2
NR
N
R
NR
N
R
NR
N
R
Der
ma
l Con
tact
1
4 N
R
NR
N
R
110
0
.000
9-2
7 N
R
8 5
NR
8
NR
D
eod
ora
nt
(Und
era
rm)
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
Ha
ir -
Non
-Col
orin
g N
R
NR
1
NR
4
3 0
.02
-2
NR
N
R
2 N
R
3 0
.5
Ha
ir -
Col
orin
g N
R
NR
N
R
NR
8
NR
N
R
NR
N
R
NR
N
R
NR
N
ail
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
Muc
ous
Mem
bra
ne
NR
N
R
NR
N
R
5 2
7 N
R
8 N
R
NR
N
R
NR
B
ath
Pro
duct
s N
R
NR
N
R
NR
2
0.0
1-0
.1
NR
N
R
NR
N
R
NR
N
R
Bab
y P
rod
uct
s N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
P
erse
a G
ratis
sim
a (A
voca
do)
But
ter
Per
sea
Gra
tissi
ma
(Avo
cado
) O
il U
nsap
on.
Sod
ium
Avo
cado
ate
Plu
kene
tia V
olub
ilis
See
d O
il [S
acha
Inch
i] P
runu
s A
rmen
iaca
(A
pric
ot)
Ker
nel O
il H
ydro
gena
ted
Apr
icot
K
erne
l Oil
Tot
als
15
NR
63
0.
2-6
1 N
R
13
NS
58
8 0.
0000
1-89
2
NR
D
urat
ion
of U
se
Le
ave
-On
15
NR
5
7 0
.5-6
N
R
NR
1
2 N
S
449
0
.000
1-4
0 2
NR
R
inse
-Off
NR
N
R
6 0
.2
1 N
R
1 N
S
139
0
.000
01
-89
NR
N
R
Exp
osur
e T
ype
Eye
Are
a
NR
N
R
9 0
.5
NR
N
R
1 N
S
25
0.0
02-1
8 N
R
NR
P
ossi
ble
Inge
stio
n
11
NR
2
3 N
R
NR
3
NS
3
8 0
.001
-5
NR
N
R
Inh
ala
tion
NR
N
R
4 N
R
NR
N
R
NR
N
S
5 0
.000
9-1
N
R
NR
D
erm
al C
onta
ct
15
NR
5
6 0
.2-3
1
NR
1
3 N
S
486
0
.000
01
-18
2 N
R
Deo
dor
an
t (U
nder
arm
) N
R
NR
N
R
NR
N
R
NR
N
R
NS
1
0.0
03-0
.1
NR
N
R
Ha
ir -
Non
-Col
orin
g N
R
NR
2
6 N
R
NR
N
R
NS
7
8 0
.000
1-8
9 N
R
NR
H
air
- C
olor
ing
NR
N
R
NR
N
R
NR
N
R
NR
N
S
10
0.1
N
R
NR
N
ail
NR
N
R
3 N
R
NR
N
R
NR
N
S
10
0.0
02-4
0 N
R
NR
M
ucou
s M
emb
ran
e N
R
NR
N
R
NR
1
NR
N
R
NS
2
4 0
.01
-9
NR
N
R
Ba
th P
rodu
cts
NR
N
R
4 N
R
NR
N
R
NR
N
S
8 4
NR
N
R
Bab
y P
rod
uct
s N
R
NR
1
NR
N
R
NR
N
R
NS
7
NR
N
R
NR
CIR Panel Book Page 44
36
Tab
le 5
a. F
requ
ency
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
. (co
ntin
ued)
NR
= N
ot r
epor
ted
to
VC
RP
or
Cou
ncil.
NS
= N
ot y
et s
urv
eye
d.
N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
)
Pru
nus
Avi
um (
Sw
eet
Che
rry)
See
d O
il P
runu
s D
omes
tica
See
d O
il [P
rune
/Plu
m]
Pru
nus
Per
sica
(P
each
) K
erne
l Oil
Pyr
us M
alus
(A
pple
) S
eed
Oil
Rib
es N
igru
m (
Bla
ck
Cur
rant
) S
eed
Oil
Rub
us Id
aeus
(R
aspb
erry
) S
eed
Oil
Tot
als
2 0.
01-0
.02
NR
0.
04
22
0.00
3-22
8
NR
53
0.
0000
01-0
.3
10
0.1-
5
Dur
atio
n of
Use
Le
ave
-On
NR
N
R
NR
N
R
16
0.0
5-2
2 8
NR
4
5 0
.000
001
-0.3
8
0.1
-5
Rin
se O
ff
2 0
.01
-+0
.02
NR
0
.04
6 0
.003
-6
NR
N
R
8 0
.05
2 N
R
Exp
osur
e T
ype
Eye
Are
a
NR
N
R
NR
N
R
NR
N
R
NR
N
R
2 0
.08
NR
N
R
Pos
sib
le In
gest
ion
N
R
NR
N
R
NR
N
R
0.0
4-2
2 1
NR
7
0.0
3-0
.1
1 N
R
Inh
ala
tion
NR
N
R
NR
N
R
NR
2
NR
N
R
NR
N
R
NR
N
R
Der
ma
l Con
tact
2
0.0
1-0
.02
NR
0
.04
18
0.0
03-2
2 8
NR
4
3 0
.000
001
-0.3
8
0.1
-5
Deo
dor
an
t (U
nder
arm
) N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
H
air
- N
on-C
olor
ing
NR
N
R
NR
N
R
4 N
R
NR
N
R
5 N
R
NR
N
R
Ha
ir -
Col
orin
g N
R
NR
N
R
NR
N
R
0.1
N
R
NR
N
R
NR
N
R
NR
N
ail
NR
N
R
NR
N
R
NR
N
R
NR
N
R
5 0
.2
NR
N
R
Muc
ous
Mem
bra
ne
2 0
.01
-0.0
2 N
R
NR
1
NR
N
R
NR
2
NR
2
NR
B
ath
Pro
duct
s N
R
NR
N
R
NR
1
0.1
-1
NR
N
R
NR
N
R
1 N
R
Bab
y P
rod
uct
s N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
S
cler
ocar
ya B
irrea
See
d O
il [M
arul
a]
Sily
bum
Mar
ianu
m S
eed
Oil
[Thi
stle
] S
olan
um L
ycop
ersi
cum
(T
omat
o) S
eed
Oil
Sol
anum
Lyc
oper
sicu
m
(Tom
ato)
Fru
it O
il T
heob
rom
a C
acao
(C
ocoa
) S
eed
But
ter
The
obro
ma
Gra
ndifl
orum
S
eed
But
ter
[Cap
uacu
]
Tot
als
29
1 N
R
0.5
1 N
R
NR
0.
01-1
44
2 0.
0000
02-3
7 15
3 0.
0000
5-7
Dur
atio
n of
Use
Le
ave
-On
23
1 N
R
0.5
1
NR
N
R
0.0
01-1
3
67
0.0
000
02-3
7 1
19
0.0
000
5-7
R
inse
-Off
6 1
NR
N
R
NR
N
R
NR
N
R
75
0.0
001
-2
34
0.0
01-1
E
xpos
ure
Typ
e
Eye
Are
a
NR
N
R
NR
N
R
NR
N
R
NR
0
.01
11
0.0
002
-9
21
0.1
-2
Pos
sib
le In
gest
ion
6
NR
N
R
NR
N
R
NR
N
R
0.0
01
33
37
49
7 In
ha
latio
n 2
NR
N
R
NR
N
R
NR
N
R
NR
2
0.4
N
R
NR
D
erm
al C
onta
ct
23
1 N
R
0.5
1
NR
N
R
0.0
01-1
4
17
0.0
000
02-3
7 1
41
0.0
000
5-7
D
eod
ora
nt
(Und
era
rm)
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
0
.001
-1
NR
0
.1
Ha
ir -
Non
-Col
orin
g 6
1 N
R
NR
N
R
NR
N
R
NR
2
4 0
.01
-2
9 0
.001
-1
Ha
ir -
Col
orin
g N
R
NR
N
R
NR
N
R
NR
N
R
NR
N
R
0.1
3
NR
N
ail
NR
N
R
NR
N
R
NR
N
R
NR
N
R
NR
0
.1-1
N
R
NR
M
ucou
s M
emb
ran
e 2
NR
N
R
NR
N
R
NR
N
R
NR
3
5 0
.02
-2
19
0.0
5-0
.1
Ba
th P
rodu
cts
NR
N
R
NR
N
R
NR
N
R
NR
N
R
4 0
.1-1
4
NR
B
aby
Pro
du
cts
NR
N
R
NR
N
R
NR
N
R
NR
N
R
8 0
.01
NR
N
R
CIR Panel Book Page 45
37
Tab
le 5
a. F
requ
ency
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
. (co
ntin
ued)
NR
= N
ot r
epor
ted
to
VC
RP
or
Cou
ncil.
NS
= N
ot y
et s
urv
eye
d.
N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
)
Trit
icum
Vul
gare
(W
heat
) G
erm
Oil
Uns
apon
ifiab
les
Whe
at G
erm
Aci
d V
acci
nium
Mac
roca
rpon
(C
ranb
erry
) S
eed
Oil
Vac
cini
um O
xyco
ccos
(C
ranb
erry
) S
eed
Oil
Viti
s V
inife
ra (
Gra
pe)
See
d O
il S
odiu
m G
rape
seed
ate
Tot
als
17
0.2
16
NR
21
0.
002-
2 4
NS
46
5 0.
001-
43
4 N
R
Dur
atio
n of
Use
Le
ave
-On
17
0.2
3
NR
1
8 0
.002
-2
3 N
S
368
0
.001
-41
4 N
R
Rin
se O
ff
NR
N
R
13
NR
3
0.0
03-0
.1
1 N
S
97
0.0
01-4
3 N
R
NR
E
xpos
ure
Typ
e
Eye
Are
a
1 N
R
NR
N
R
2 N
R
NR
N
S
14
0.0
1-5
N
R
NR
P
ossi
ble
Inge
stio
n
NR
N
R
NR
N
R
NR
0
.3
NR
N
S
34
0.0
3-7
N
R
NR
In
ha
latio
n N
R
NR
N
R
NR
N
R
NR
N
R
NS
6
0.0
01-7
N
R
NR
D
erm
al C
onta
ct
17
0.2
N
R
NR
1
7 0
.002
-2
4 N
S
401
0
.001
-41
NR
N
R
Deo
dor
an
t (U
nder
arm
) N
R
NR
N
R
NR
N
R
NR
N
R
NS
N
R
0.0
01-0
.2
NR
N
R
Ha
ir -
Non
-Col
orin
g N
R
NR
1
6 N
R
4 0
.01
-0.1
N
R
NS
4
6 0
.01
-0.3
4
NR
H
air
- C
olor
ing
NR
N
R
NR
N
R
NR
N
R
NR
N
S
10
43
NR
N
R
Na
il N
R
NR
N
R
NR
N
R
NR
N
R
NS
8
0.0
01-3
5 N
R
NR
M
ucou
s M
emb
ran
e N
R
NR
N
R
NR
1
0.0
03-0
.1
NR
N
S
21
0.0
01-7
N
R
NR
B
ath
Pro
duct
s N
R
NR
N
R
NR
N
R
NR
N
R
NS
8
0.0
1-2
N
R
NR
B
aby
Pro
du
cts
NR
N
R
NR
N
R
NR
N
R
NR
N
S
5 N
R
NR
N
R
H
ydro
gena
ted
Gra
pese
ed O
il B
assi
a La
tifol
ia S
eed
But
ter
Cam
ellia
Kis
si S
eed
Oil
Cra
mbe
Aby
ssin
ica
See
d O
il G
arci
nia
Indi
ca S
eed
But
ter
Hip
poph
ae R
ham
noid
es
Fru
it O
il
Tot
als
7 0.
3-0.
5 22
N
S
47
NS
26
N
S
30
NS
7
NS
D
urat
ion
of U
se
Le
ave
-On
4 0
.3-0
.5
17
NS
3
4 N
S
15
NS
2
7 N
S
7 N
S
Rin
se O
ff
3 0
.5
5 N
S
13
NS
1
1 N
S
3 N
S
NR
N
S
Exp
osur
e T
ype
Eye
Are
a
NR
N
R
4 N
S
4 N
S
1 N
S
1 N
S
1 N
S
Pos
sib
le In
gest
ion
1
0.5
N
R
NS
1
NS
1
NS
3
NS
N
R
NS
In
ha
latio
n N
R
NR
N
R
NS
N
R
NS
N
R
NS
N
R
NS
N
R
NS
D
erm
al C
onta
ct
5 0
.5
22
NS
3
6 N
S
8 N
S
30
NS
6
NS
D
eod
ora
nt
(Und
era
rm)
NR
N
R
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
Ha
ir -
Non
-Col
orin
g 1
NR
N
R
NS
1
1 N
S
14
NS
N
R
NS
N
R
NS
H
air
- C
olor
ing
NR
N
R
NR
N
S
NR
N
S
4 N
S
NR
N
S
NR
N
S
Na
il 1
0.3
N
R
NS
N
R
NS
N
R
NS
N
R
NS
1
NS
M
ucou
s M
emb
ran
e 1
NR
5
NS
1
NS
N
R
NS
1
NS
N
R
NS
B
ath
Pro
duct
s N
R
NR
N
R
NS
1
NS
N
R
NS
N
R
NS
N
R
NS
B
aby
Pro
du
cts
NR
N
R
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
CIR Panel Book Page 46
38
Tab
le 5
a. F
requ
ency
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
. (co
ntin
ued)
NR
= N
ot r
epor
ted
to
VC
RP
or
Cou
ncil.
NS
= N
ot y
et s
urv
eye
d.
N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
) N
o. o
f U
ses
(201
0)
Con
c. o
f U
se
(201
0) (%
)
Hip
poph
ae R
ham
noid
es O
il Lu
ffa C
ylin
dric
a S
eed
Oil
Lupi
nus
Alb
us S
eed
Oil
Lyci
um B
arba
rum
See
d O
il O
rbig
nya
Spe
cios
a K
erne
l O
il P
assi
flora
Edu
lis S
eed
Oil
Tot
als
15
NS
21
N
S
1 N
S
2 N
S
8 N
S
62
NS
D
urat
ion
of U
se
Le
ave
-On
10
NS
2
1 N
S
1 N
S
2 N
S
1 N
S
53
NS
R
inse
Off
5 N
S
NR
N
S
NR
N
S
NR
N
S
7 N
S
9 N
S
Exp
osur
e T
ype
Eye
Are
a
NR
N
S
1 N
S
NR
N
S
1 N
S
NR
N
S
3 N
S
Pos
sib
le In
gest
ion
N
R
NS
9
NS
N
R
NS
1
NS
N
R
NS
1
4 N
S
Inh
ala
tion
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
3 N
S
Der
ma
l Con
tact
1
NS
2
1 N
S
1 N
S
2 N
S
NR
N
S
49
NS
D
eod
ora
nt
(Und
era
rm)
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
Ha
ir -
Non
-Col
orin
g 6
NS
N
R
NS
N
R
NS
N
R
NS
5
NS
1
0 N
S
Ha
ir -
Col
orin
g N
R
NS
N
R
NS
N
R
NS
N
R
NS
3
NS
3
NS
N
ail
8 N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
Muc
ous
Mem
bra
ne
1 N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
1 N
S
Ba
th P
rodu
cts
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
Bab
y P
rod
uct
s N
R
NS
N
R
NS
N
R
NS
N
R
NS
N
R
NS
N
R
NS
P
unic
a G
rana
tum
See
d O
il R
osa
Can
ina
Fru
it O
il R
ubus
Cha
mem
orus
See
d O
il V
acci
nium
Myr
tillu
s S
eed
Oil
Vac
cini
um V
itis-
Idae
a S
eed
Oil
Van
illa
Pla
nifo
lia F
ruit
Oil
Tot
als
46
NS
12
1 N
S
3 N
S
33
NS
9
NS
9
NS
D
urat
ion
of U
se
Le
ave
-On
44
NS
1
06
NS
3
NS
3
2 N
S
9 N
S
8 N
S
Rin
se O
ff
2 N
S
15
NS
N
R
NS
1
NS
N
R
NS
1
NS
E
xpos
ure
Typ
e
Eye
Are
a
2 N
S
17
NS
N
R
NS
N
R
NS
N
R
NS
2
NS
P
ossi
ble
Inge
stio
n
30
NS
7
NS
N
R
NS
2
9 N
S
NR
N
S
NR
N
S
Inh
ala
tion
NR
N
S
1 N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
Der
ma
l Con
tact
4
6 N
S
109
N
S
3 N
S
33
NS
1
NS
9
NS
D
eod
ora
nt
(Und
era
rm)
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
Ha
ir -
Non
-Col
orin
g N
R
NS
9
NS
N
R
NS
N
R
NS
N
R
NS
N
R
NS
H
air
- C
olor
ing
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
Na
il N
R
NS
1
NS
N
R
NS
N
R
NS
8
NS
N
R
NS
M
ucou
s M
emb
ran
e 2
NS
3
NS
N
R
NS
N
R
NS
N
R
NS
1
NS
B
ath
Pro
duct
s N
R
NS
1
NS
N
R
NS
N
R
NS
N
R
NS
N
R
NS
B
aby
Pro
du
cts
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
NR
N
S
CIR Panel Book Page 47
39
Tab
le 5
b. C
urre
nt a
md
hist
oric
al fr
eque
ncy
and
conc
entr
atio
n of
use
acc
ordi
ng to
dur
atio
n an
d ty
pe o
f exp
osur
e -
pre
viou
sly
revi
ewed
ingr
edie
nts
#
of
Use
s C
onc.
of
Use
(%
) #
of
Use
s C
onc.
of
Use
(%
) #
of
Use
s C
onc.
of
Use
(%
) #
of
Use
s C
onc.
of
Use
(%
)
C
arth
amus
Tin
ctor
ius
(Saf
flow
er)
See
d O
il E
laei
s G
uine
ensi
s (P
alm
) O
il E
laei
s G
uine
ensi
s (P
alm
) K
erne
l Oil
Hyd
roge
nate
d P
alm
Oil
dat
a ye
ar
2002
20
10
2003
20
10
1997
20
10
1997
20
10
1997
20
10
1997
20
10
1997
20
10
1997
20
10
Tot
als
142
508
0.00
005-
84
NS
36
27
2 **
0.
002-
48
11
77
**
0.05
-23
13
152
**
0.2-
30
Dur
atio
n of
Use
Le
ave
-On
114
4
02
0.0
000
5-
84
NS
2
8 1
71
**
0.0
08-1
3 9
60
**
0.8
-3
13
134
**
0
.2-3
0
Rin
se O
ff
28
106
0
.001
-72
NS
8
101
**
0
.002
-48
2 1
7 **
0
.05
-23
NR
1
8 **
2
Exp
osur
e T
ype
Eye
Are
a
5 1
5 1
-6
NS
N
R
12
**
0.0
4-2
N
R
10
**
0.8
1
61
**
0.2
-30
Pos
sib
le In
gest
ion
1
8 8
3 0
.1-6
0 N
S
NR
1
1 **
2
NR
6
**
NR
3
12
**
2-3
0
Inh
ala
tion
3 5
5 N
S
1 3
**
NR
N
R
NR
**
N
R
NR
N
R
**
1
Der
ma
l Con
tact
1
13
395
0
.001
-72
NS
3
6 2
29
**
0.0
02-4
8 1
1 7
1 **
0
.05
-2
12
123
**
0
.4-3
0
Deo
dor
an
t (u
nder
arm
) N
R
NR
N
R
NS
N
R
NR
**
N
R
NR
N
R
**
NR
N
R
NR
**
N
R
Ha
ir -
Non
-Col
orin
g 2
8 7
9 0
.000
05
-2
7 N
S
NR
4
3 **
2
-34
NR
6
**
0.9
-23
NR
N
R
**
NR
Ha
ir-C
olor
ing
NR
2
0 1
NS
N
R
NR
**
N
R
NR
N
R
**
NR
N
R
NR
**
N
R
Na
il 1
32
84
NS
N
R
NR
**
N
R
NR
N
R
**
3 N
R
NR
**
N
R
Muc
ous
Mem
bra
ne
NR
3
1 N
R
NS
7
68
**
0.0
02-4
8 N
R
10
**
0.0
5 N
R
17
**
2
Ba
th P
rodu
cts
NR
3
7 N
S
NR
N
R
**
NR
N
R
1 **
N
R
NR
N
R
**
NR
Bab
y P
rod
uct
s N
R
6 1
0 N
S
1 2
**
NR
N
R
NR
**
N
R
NR
N
R
**
NR
H
ydro
gena
ted
Pal
m K
erne
l Oil
Gos
sypi
um H
erba
ceum
(C
otto
n) S
eed
Oil
Hyd
roge
nate
d C
otto
nsee
d O
il O
ryza
Sat
iva
(Ric
e) B
ran
Oil
dat
a ye
ar
199
7 2
010
199
7 2
010
199
8 2
010
199
8 2
010
199
8 2
010
199
8 2
010
200
2 2
010
200
0-
200
3 2
010
Tot
als
29
47
**
0.4-
13
4 83
0.00
4-32
27
2 36
2 **
0.
001-
24
39
371
0.1-
39
0.00
03-7
8
Dur
atio
n of
Use
**
Le
ave
-On
27
45
**
0.4
-13
1 6
8 0
.08
-32
272
3
58
**
0.0
01-2
4 3
2 2
67
0.1
-8
0.0
003
-78
Rin
se-O
ff
2 2
**
0.6
-2
3 1
5 **
0
.004
-29
NR
4
**
0.0
1-0
.1
7 1
04
0.2
-39
0.0
05-6
Exp
osur
e T
ype
**
Eye
Are
a
5 2
**
2-1
0 N
R
4
0.1
-11
116
1
55
**
0.5
-24
NR
5
0.1
-1
0.5
-0.8
Pos
sib
le In
gest
ion
2
5 **
3
-13
NR
9
**
0.2
-1
151
N
R
**
8-1
2 N
R
17
0.1
-1
0.1
-8
Inh
ala
tion
NR
1
**
NR
N
R
12
**
0.2
N
R
NR
**
N
R
NR
1
1 N
R
0.1
Der
ma
l Con
tact
2
4 4
7 **
0
.4-1
3 4
78
**
0.0
04-2
9 1
56
356
**
0
.001
-24
36
321
0
.1-3
9 0
.000
3-2
7
Deo
dor
an
t (u
nder
arm
) N
R
NR
**
N
R
NR
1
**
0.2
N
R
NR
**
N
R
NR
N
R
NR
0
.5
Ha
ir -
Non
-Col
orin
g N
R
NR
**
N
R
NR
2
**
NR
N
R
4 **
0
.01
-0.1
3
33
0.3
0
.005
-0.5
Ha
ir-C
olor
ing
NR
N
R
**
NR
N
R
NR
**
N
R
NR
N
R
**
NR
N
R
NR
N
R
0.3
Na
il N
R
NR
**
N
R
NR
1
**
0.5
-32
NR
N
R
**
NR
2
5 N
R
0.0
2-7
8
Muc
ous
Mem
bra
ne
2 2
**
0.9
-2
NR
7
**
0.0
04-
0.0
1 N
R
NR
**
N
R
NR
4
8 1
0.0
006
-6
Ba
th P
rodu
cts
NR
N
R
**
NR
N
R
NR
**
N
R
NR
N
R
**
NR
1
17
,1-3
9 0
.2
Bab
y P
rod
uct
s N
R
NR
**
N
R
NR
N
R
**
NR
N
R
8 **
N
R
NR
1
NR
N
R
NR
- n
ot r
epor
ted
to th
e V
CR
P o
r th
e C
oun
cil
** c
once
ntra
tion
of u
se d
ata
wer
e n
ot g
iven
in th
e or
igin
al r
epor
t
CIR Panel Book Page 48
40
Tab
le 5
b. C
urre
nt a
md
hist
oric
al fr
eque
ncy
and
conc
entr
atio
n of
use
* ac
cord
ing
to d
urat
ion
and
type
of e
xpos
ure
- p
revi
ousl
y re
view
ed in
gred
ient
s (c
ontin
ued)
# o
f U
ses
Con
c. o
f U
se (
%)
# o
f U
ses
Con
c. o
f U
se (
%)
# o
f U
ses
Con
c. o
f U
se (
%)
# o
f U
ses
Con
c. o
f U
se (
%)
O
ryza
Sat
iva
(Ric
e) G
erm
Oil
Ses
amum
Indi
cum
(S
esam
e) S
eed
Oil
Ses
amum
Indi
cum
(S
esam
e) O
il U
nsap
onifi
able
s Z
ea M
ays
(Cor
n) O
il
dat
a ye
ar
200
2 2
010
200
0-
200
3 2
010
198
7 2
010
198
7 2
010
198
7 2
010
198
7 2
010
200
7 2
010
200
6 2
010
Tot
als
6 34
0.
1 0.
003-
3 25
3 48
0 ≤1
- >
50
NS
N
R
17
NR
N
S
498
598
0.00
003-
14
NS
Dur
atio
n of
Use
Le
ave
-On
5 2
9 0
.1
0.0
03-3
3
5 3
74 ≤1
- >
50
NS
N
R
17
NR
N
S
241
3
61
0.0
000
3-
14
NS
Rin
se O
ff
1 5
NR
0
.003
-3
218
1
06 ≤1
- >
50
NS
N
R
NR
N
R
NS
2
57
237
0
.001
-0
.07
NS
Exp
osur
e T
ype
Eye
Are
a
NR
2
NR
0
.01
-1
6 1
4 ≤1
- >
50
NS
N
R
NR
N
R
NS
3
9 3
5 0
.000
8-
0.2
N
S
Pos
sib
le In
gest
ion
N
R
4 N
R
0.1
-3
59
52
≤1
- 1
0 N
S
NR
1
1 N
R
NS
2
9 3
0 0
.003
-10
NS
Inh
ala
tion
NR
N
R
NR
N
R
NR
5
NR
N
S
NR
N
R
NR
N
S
1 1
0.0
01-0
.1
NS
Der
ma
l Con
tact
6
32
0.1
0
.003
-3
233
4
14
≤1
-50
NS
NR
1
7 N
R
NS
2
76
371
0
.000
03
-1
4 N
S
Deo
dor
an
t (u
nder
arm
) N
R
NR
N
R
0.0
03
NR
N
R
NR
N
S
NR
N
R
NR
N
S
1 4
NR
N
S
Ha
ir -
Non
-Col
orin
g N
R
NR
N
R
NR
1
1 5
9 ≤1
-50
NS
NR
N
R
NR
N
S
38
40
0.0
001
-0
.02
NS
Ha
ir-C
olor
ing
NR
N
R
NR
N
R
NR
N
R
NR
N
S
NR
N
R
NR
N
S
182
1
83
0.0
04-
0.0
07
NS
Na
il N
R
NR
N
R
NR
3
7 ≤1
-10
NS
NR
N
R
NR
N
S
1 3
0.0
01-5
N
S
Muc
ous
Mem
bra
ne
NR
1
NR
0
.003
-0
.005
N
R
28
NR
N
S
NR
N
R
NR
N
S
2 2
0.0
04-
0.0
1 N
S
Ba
th P
rodu
cts
NR
1
NR
0
.5
3 5
1-5
0 N
S
NR
N
R
NR
N
S
NR
N
R
0.0
01-
0.0
1 N
S
Bab
y P
rod
uct
s N
R
NR
N
R
NR
2
3 1
-50
NS
N
R
NR
N
R
NS
8
8 0
.004
N
S
NR
- n
ot r
epor
ted
to th
e V
CR
P o
r th
e C
oun
cil
** c
once
ntr
atio
n o
f use
dat
a w
ere
not
giv
en in
the
orig
ina
l rep
ort
CIR Panel Book Page 49
41
T
able
5b.
Cur
rent
am
d hi
stor
ical
freq
uenc
y an
d co
ncen
trat
ion
of u
se*
acco
rdin
g to
dur
atio
n an
d ty
pe o
f exp
osur
e -
pre
viou
sly
revi
ewed
ingr
edie
nts
(con
tinue
d)
#
of
Use
s C
onc.
of
Use
(%
) #
of
Use
s C
onc.
of
Use
(%
) #
of
Use
s C
onc.
of
Use
(%
) #
of
Use
s C
onc.
of
Use
(%
)
Z
ea M
ays
(Cor
n) G
erm
Oil
Z
ea M
ays
(Cor
n) O
il U
nsap
onifi
able
s P
erse
a G
ratis
sim
a (A
voca
do)
Oil
Trit
icum
Vul
gare
(W
heat
) G
erm
Oil
dat
a ye
ar
200
7 2
010
200
6 2
010
200
7 2
010
200
6 2
010
200
1 2
010
200
1 2
010
200
1 2
010
200
1 2
010
Tot
als
37
53
0.2-
25
NS
7
1 N
R
NS
18
8 88
3 0.
001-
23
0.00
01-9
8 30
3 52
7 0.
0000
2-18
0.
0001
-28
Dur
atio
n of
Use
Le
ave
-On
25
34
3-2
5 N
S
6 1
NR
N
S
40
657
0
.001
-23
0.0
005
-98
80
373
0
.000
02
-1
8 0
.000
1-2
8
Rin
se-O
ff
12
19
0.2
-3
NS
1
NR
N
R
NS
1
48
226
0
.1-5
0
.000
1-1
5 2
23
154
0
.000
02
-5
0.0
01-2
Exp
osur
e T
ype
Eye
Are
a
NR
N
R
NR
N
S
NR
N
R
NR
N
S
8 2
4 0
.1-3
0
.05
-2
9 1
2 0
.000
04
-3
0.0
001
-0.5
Pos
sib
le In
gest
ion
N
R
NR
N
R
NS
N
R
NR
N
R
NS
2
9 6
0 0
.7-2
1 0
.05
-26
33
29
0.1
-3
0.3
-5
Inh
ala
tion
NR
N
R
NR
N
S
NR
N
R
NR
N
S
2 1
1 0
.02
-3
0.0
1-8
2
7 0
.000
2-
0.0
1 0
.000
1-0
.00
05
Der
ma
l Con
tact
3
1 5
0 3
-25
NS
7
1 N
R
NS
1
65
685
0
.001
-23
0.0
005
--98
2
20
360
0
.000
02
-1
8 0
.000
5-2
3
Deo
dor
an
t (u
nder
arm
) N
R
NR
N
R
NS
N
R
NR
N
R
NS
N
R
NR
N
R
0.1
N
R
NR
0
.02
NR
Ha
ir -
Non
-Col
orin
g 4
3 0
.2
NS
N
R
NR
N
R
NS
1
1 1
89
0.0
02-3
0
.000
1-4
1 6
3 1
42
0.0
001
-2
0.0
001
-<1
Ha
ir-C
olor
ing
NR
N
R
NR
N
S
NR
N
R
NR
N
S
8 N
R
NR
0
.3
12
20
0.1
0
.01
-0.2
Na
il N
R
NR
N
R
NS
N
R
NR
N
R
NS
4
7 0
.4-1
9 0
.001
-34
4 2
0.1
-4
0.1
-28
Muc
ous
Mem
bra
ne
4 3
3 N
S
NR
N
R
NR
N
S
NR
4
3 0
.1-5
0
.002
-3
3 2
2 0
.02
-1
0.0
1-0
.5
Ba
th P
rodu
cts
3 4
NR
N
S
NR
N
R
NR
N
S
5 2
5 0
.1-5
0
.6-6
1
2 0
.001
-2
0.5
Bab
y P
rod
uct
s 2
4 N
R
NS
N
R
NR
N
R
NS
N
R
9 N
R
NR
1
9 0
.5
NR
NR
- n
ot r
epor
ted
to th
e V
CR
P o
r th
e C
oun
cil
** c
once
ntr
atio
n o
f use
dat
a w
ere
not
giv
en in
the
orig
ina
l rep
ort
CIR Panel Book Page 50
42
Table 5c. Ingredients not reported to be used
Brassica Campestris (Rapeseed) Oil Unsaponifiables Potasium Rapeseedate Rapeseed Acid Sodium Rapeseedate Hydroganted Safflower Seed Oil Potassium Safflowerate Safflower Acid Sodium Safflowerate Elaeis Guineensis (Palm) Butter Hydrogenated Palm Acid Potassium Hydrogenated Palmate Sodium Hydrogenated Palmate Soy Acid Potassium Soyate Sodium Soyate Cottonseed Acid Sunflower Seed Acid Olive Acid Rice Bran Acid Hydrogenated Rice Bran Oil Oryza Sativa (Rice) Seed Oil Hydrogenated Sesame Seed Oil Sodium Sesameseedate Sesamum Indicum (Sesame) Seed Butter Corn Acid Potassium Cornate Adansonia Digitata Seed Oil Hydrogenated Adansonia Digitata Seed Oil Amaranthus Hypochondriacus Seed Oil Arctium Lappa Seed Oil Hydrogenated Argania Spinosa Kernel Oil Hydrogenated Camelina Sativa Seed Oil Citrus Aurantifolia (Lime) Seed Oil Citrus Aurantifolia (Lime) Seed Oil Unsaponifiables Hydrogenated Lime Seed Oil Hydrogenated Lime Seed Oil Unsaponifiables Citrus Aurantium Dulcis (Orange) Seed Oil Citrus Aurantium Dulcis (Orange) Seed Oil Unsaponifiables Hydrogenated Orange Seed Oil Hydrogenated Orange Seed Oil Unsaponifiables Citrus Grandis (Grapefruit) Seed Oil Unsaponifiables Hydrogenated Grapefruit Seed Oil
Hydrogenated Grapefruit Seed Oil Unsaponifiables Citrus Limon (Lemon) Seed Oil Coix Lacryma-Jobi (Job's Tears) Seed Oil Hydrogenated Pumpkin Seed Oil Cynara Cardunculus Seed Oil [Artichoke] Fragaria Ananassa (Strawberry) Seed Oil Fragaria Chiloensis (Strawberry) Seed Oil Fragaria Vesca (Strawberry) Seed Oil Fragaria Virginiana (Strawberry) Seed Oil Guizotia Abyssinica Seed Oil [Ramtil] Hydrogenated Meadowfoam Seed Oil Babassu Acid Potassium Babassuate Hydrogenated Apricot Kernel Oil Hydrogenated Apricot Kernel Oil Unsaponifiables Prunus Armeniaca (Apricot) Kernel Oil Unsaponifiables Hydrogenated Peach Kernel Oil Hydrogenated Black Currant Seed Oil Ribes Rubrum (Currant) Seed Oil Hydrogenated Raspberry Seed Oil Sodium Cocoa Butterate Sodium Theobroma Grandiflorum Seedate Torreya Nucifera Seed Oil [Kaya] Hydrogenated Wheat Germ Oil Hydrogenated Wheat Germ Oil Unsaponifiables Triticum Aestivum (Wheat) Germ Oil Hydrogenated Cranberry Seed Oil Vitis Vinifera (Grape) Seed Oil Sodium Grapeseedate Hydrogenated Grapeseed Oil Bassia Butyracea Seed Butter Brassica Napus Seed Oil [Rapeseed] Brassica Oleracea Acephala Seed Oil [Kale] Hippophae Rhamnoides Seed Oil [Sea-Buckthorn] Lupinus Albus Oil Unsaponifiables Morinda Citrifolia Seed Oil [Noni] Hydrogenated Passiflora Edulis Seed Oil Hydrogenated Punica Granatum Seed Oil Hydrogenated Rosa Canina Fruit Oil Rubus Chamaemorus Seed Oil [Cloudberry] Vaccinium Corymbosum (Blueberry) Seed Oil Vanilla Planifolia Fruit Oil [Vanilla]
CIR Panel Book Page 51
43
5d. Ingredients for which concentration of use information has not yet been provided
Carthamus Tinctorius Safflower Seed Oil Oryza Sativea (Rice) Germ Oil Sesamum Indicum (Sesame) Seed Oil Hydrogenated Sesame Seed Oil Sesamum Indicum (Sesame) Oil Unsaponifiables Sodium Sesameseedate Zea Mays (Corn) Oil Zea Mays (Corn) Germ Oil Zea Mays (Corn) Oil Unsaponifiables Corn Acid Potassium Cornate Orgibnuya Cohune Seed Oil [Cohune] Plukenetia Volubilis Seed Oil [Sacha Inchi] Triticum Vulgare (Wheat) Germ Oil Unsaponifiables Bassia Butyracea Seed Butter Bassia Latifolia Seed Butter [Mahwa] Brassica Napus Seed Oil [Rapeseed] Brassica Oleracea Acephala Seed Oil [Kale] Camellia Kissi Seed Oil [Tea] Crambe Abyssinica Seed Oil [Abyssinian Mustard]
Garcinia Indica Seed Butter [Kokum] Hippophae Rhamnoides Fruit Oil [Sea-Buckthorn] Hippophae Rhamnoides Oil [Sea-Buckthorn] Hippophae Rhamnoides Seed Oil [Sea-Buckthorn] Luffa Cylindrica Seed Oil [Luffa] Lupinus Albus Seed Oil [White Lupine] Lupinus Albus Oil Unsaponifiables Lycium Barbarum Seed Oil [Goji Berry] Morinda Citrifolia Seed Oil [Noni] Orbignya Speciosa Kernel Oil [Babassu] Passiflora Edulis Seed Oil [Passion Fruit] Hydrogenated Passiflora Edulis Seed Oil Punica Granatum Seed Oil [Pomegrante] Hydrogenated Punica Granatum Seed Oil Rosa Canina Fruit Oil [Dog Rose] Hydrogenated Rosa Canina Fruit Oil Rubus Chamaemorus Seed Oil [Cloudberry] Vaccinium Corymbosum (Blueberry) Seed Oil Vaccinium Myrtillus Seed Oil [Bilberry] Vaccinium Vitis-Idaea Seed Oil [Ligonberry] Vanilla Planifolia Fruit Oil [Vanilla]
CIR Panel Book Page 52
44
Tab
le 6
. N
on-f
ood,
non
-cos
met
ic u
ses
of e
dibl
e oi
ls.
3
Oil
Use
ra
pes
eed
/can
ola
ru
bber
add
itive
· l
ub
rican
ts · f
at l
iqu
orin
g of
lea
ther
· va
rnis
hes
and
lacq
uer
s · t
extil
e ch
emic
als
· det
erge
nt
add
itive
s · p
last
iciz
ers ·
we
ed c
ontr
ol · m
edic
ina
l pro
cedu
res
sun
flow
er
ma
nufa
ctu
ring
of la
cqu
ers,
cop
olym
ers,
pol
yest
er
film
s, m
odifi
ed r
esin
s, p
last
iciz
ers,
alk
yld
res
ins,
oth
er s
imila
r p
rod
ucts
pa
lm
cra
yon
and
ca
ndle
man
ufa
ctu
ring · t
in p
late
indu
stry
pa
l m k
ern
el
det
erge
nt
pro
duct
ion ·
ph
arm
ace
utic
al · c
rayo
n a
nd c
and
le m
anu
fact
urin
g · t
in p
late
indu
stry
nig
er
pai
nt ·
lub
rica
nt · p
ha
rma
ceut
ica
l ol
ive
te
xtile
ind
ust
ry · p
ha
rmac
eutic
al
coco
a p
harm
ace
utic
al
gra
pes
eed
su
bst
itute
for
linse
ed o
il in
the
ma
nufa
ctu
re o
f pai
nts
, an
d va
rnis
hes
per
illa
su
bst
itute
for
linse
ed o
il in
the
ma
nufa
ctu
re o
f pai
nts
, va
rnis
hes
, lin
oleu
m, o
ilclo
thes
, an
d p
rintin
g in
ks
fals
e fla
x d
ryin
g oi
l · m
anu
fact
urin
g of
va
rnis
hes
and
pa
ints
wa
term
elon
ill
um
ina
tion
ap
ricot
p
harm
ace
utic
al
coh
une
ma
nufa
ctu
ring
of s
oap
s, c
and
les,
an
d n
ight
light
s · c
otto
n d
yein
g · oi
ntm
ent b
ase
· s
ubst
itute
for
coco
a b
utte
r in
fo
od
linse
ed
ma
nufa
ctu
ring
of li
nol
eum
, cl
oth
oil,
prin
ting
and
lith
ogra
phi
c in
ks,
core
oils
, lin
ings
, pac
kin
gs,
oil-m
odifi
ed
alk
yd r
esin
s, c
aulk
ing
com
pou
nds,
put
ties,
lea
ther
-fin
ishi
ng
com
pou
nds,
lub
rica
nts,
gre
ase
s, p
olis
hes
, p
yrot
ech
nic
com
pos
ition
s · pig
men
t bin
der
in p
etro
chem
ica
ls ·
con
cret
e p
rote
ctor
· s
tab
ilize
r/p
last
iciz
er fo
r vi
nyl
p
last
ics ·
ind
ustr
ial s
tain
s · ju
te t
extil
es · d
ryin
g oi
l in
pain
ts a
nd v
arn
ish
es
CIR Panel Book Page 53
45
Tab
le 7
. Clin
ical
irrit
atio
n an
d se
nsiti
zatio
n st
udie
s on
veg
etab
le o
ils.
Ingr
edie
nt a
nd C
once
ntra
tion
Sub
ject
s C
ompl
eted
M
etho
d R
esul
ts
Ref
eren
ce
0.0
1% A
dan
soni
a D
igita
ta S
eed
Oil
[Ba
oba
b] in
a li
p p
rod
uct
106
H
RIP
T w
ith 0
.2 g
test
ma
teria
l, se
mi-o
cclu
ded
n
ot a
der
ma
l irr
itatio
n o
r se
nsi
tizer
11
6
100
% A
da
nso
nia
Dig
itata
See
d O
il [B
aob
ab]
107
H
RIP
T w
ith 0
.02
-0.0
5 m
l tes
t m
ate
rial,
sem
i-oc
clu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
117
1%
Ast
roca
ryu
m M
uru
mu
ru S
eed
But
ter
[Mu
rum
uru
] in
a li
pst
ick
97
HR
IPT
with
15
0 m
g te
st m
ater
ial,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
tion
or
sen
sitiz
er
118
4% A
stro
cary
um
Mu
rum
uru
See
d B
utte
r in
a li
pst
ick
108
H
RIP
T,
occl
ud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
11
9
4%
Ast
roca
ryu
m M
uru
mu
ru S
eed
But
ter
in a
lip
stic
k 1
08
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
120
4%
Ast
roca
ryu
m M
uru
mu
ru S
eed
But
ter
in a
lip
stic
k 1
08
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
121
4%
Ast
roca
ryu
m M
uru
mu
ru S
eed
But
ter
in a
lip
stic
k 1
06
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
122
4%
Ast
roca
ryu
m M
uru
mu
ru S
eed
But
ter
in a
lip
stic
k 1
06
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
123
4%
Ast
roca
ryu
m M
uru
mu
ru S
eed
But
ter
in a
lip
stic
k 1
08
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
124
3%
Ave
na
Sat
iva
(O
at)
Ker
ne
l Oil
in a
bod
y a
nd h
and
fo
rmu
latio
n 1
00
HR
IPT
with
0.2
ml,
occl
uded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
125
1%
Bor
ago
Offi
cin
alis
See
d O
il in
a b
ody
an
d h
and
fo
rmu
latio
n 2
13
HR
IPT
with
0.2
g, o
cclu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
126
5%
Hyd
roge
na
ted
Rap
esee
d O
il in
a b
ab
y oi
l 1
05
HR
IPT
with
0.2
ml,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
12
7
0.5
% B
rass
ica
Ole
race
a It
alic
a (
Bro
ccol
i) S
eed
Oil
in a
h
air
cond
ition
er
102
H
RIP
T w
ith 1
50
µl o
f tes
t mat
eria
l, 10
% d
ilutio
n,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
tion
or
sen
sitiz
er
128
0.0
985
% C
amel
lia S
inen
sis
See
d O
il in
a li
pst
ick
108
H
RIP
T w
ith 0
.2 g
, occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
12
9
0.0
985
% C
amel
lia S
inen
sis
See
d O
il in
a li
pst
ick
108
H
RIP
T w
ith 0
.2 g
, occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
13
0
74.
7% C
anol
a O
il in
a b
ody
oil
101
H
RIP
T w
ith 1
50
µl t
est
ma
teria
l, se
mi-o
cclu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
131
0.1
% C
ary
oca
r B
raili
nes
e F
ruit
Oil
in a
lip
stic
k 1
00
HR
IPT
with
20
0 m
g te
st m
ater
ial,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
13
2
2%
Citr
ullu
s La
nat
us
(Wa
term
elon
) S
eed
Oil
in a
faci
al
oil
105
H
RIP
T,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
13
3
0.5
% E
uter
pe
Ole
race
a F
ruit
Oil
in a
n e
ye t
rea
tmen
t 1
04
HR
IPT
with
15
0 µ
l tes
t m
ate
rial,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
13
4
0.1
9% G
lyci
ne
Soj
a (
Soy
bea
n)
Un
sapo
nifi
able
s in
a fa
ce
and
nec
k p
rodu
ct
50
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itatio
n o
r se
nsi
tizer
13
5
CIR Panel Book Page 54
46
Tab
le 7
. Clin
ical
irrit
atio
n an
d se
nsiti
zatio
n st
udie
s on
veg
etab
le o
ils.
Ingr
edie
nt a
nd C
once
ntra
tion
Sub
ject
s C
ompl
eted
M
etho
d R
esul
ts
Ref
eren
ce
39%
Hyd
roge
na
ted
Soy
bea
n O
il in
a li
pst
ick
108
H
RIP
T,
occl
ud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
13
6
2%
Hel
ian
thu
s A
nnu
us
(Sun
flow
er)
See
d O
il U
nsa
pon
ifiab
les
in a
nig
ht p
rodu
ct
100
H
RIP
T,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
tion
or
sen
sitiz
er
135
2% H
elia
nth
us
An
nuu
s (S
unflo
wer
) S
eed
Oil
Un
sap
onifi
able
s in
a fa
ce a
nd
nec
k p
rod
uct
1
00
HR
IPT
, se
mi-o
cclu
ded
n
ot a
der
ma
l irr
itatio
n o
r se
nsi
tizer
13
5
0.3
1% Ir
vin
gia
Ga
nen
sis
Ker
nel
Bu
tter
[D
ika]
in a
face
a
nd n
eck
pro
duct
5
2 H
RIP
T,
occl
ud
ed
not
a d
erm
al i
rrita
tion
or
sen
sitiz
er
135
71.
3% L
imn
anth
es A
lba
(M
ead
owfo
am
) S
eed
Oil
in a
fa
cia
l rep
air
pro
duct
1
09
HR
IPT
, se
mi-o
cclu
ded
7 s
ubj
ects
ha
d + o
n th
e fir
st d
ay
of t
he
ind
uctio
n o
nly
, n
o ot
her
rea
ctio
ns.
Not
a
der
ma
l irr
itant
or
sen
sitiz
er.
137
9.4
% L
inu
m U
sita
tissi
mu
m (
Lin
seed
) S
eed
Oil
in
ma
sca
ra
105
H
RIP
T w
ith 0
.2 g
test
ma
teria
l, se
mi-o
cclu
ded
n
ot a
der
ma
l irr
itatio
n o
r se
nsi
tizer
13
8
3.8
7% M
angi
fera
Ind
ica
(Man
go)
See
d O
il in
an
eye
liner
1
02
HR
IPT
with
0.2
g o
f tes
t m
ate
rial,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
13
9
2%
Ma
ngi
fera
Ind
ica
(M
an
go)
See
d O
il in
a li
pst
ick
100
H
RIP
T w
ith 1
50
µl t
est
ma
teria
l, se
mi-o
cclu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
140
9%
Ma
ngi
fera
Ind
ica
(M
an
go)
See
d B
utte
r in
a b
ody
pro
duc
t 1
02
HR
IPT
with
0.2
g, s
emi-o
cclu
ded
n
ot a
sen
sitiz
er
141
1%
Ma
ngi
fera
Ind
ica
(M
an
go)
See
d B
utte
r in
a fa
cia
l lo
tion
1
00
HR
IPT
with
20
0 µ
l tes
t m
ate
rial,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
14
2
3%
Mor
inga
Pte
rygo
sper
na
See
d O
il in
an
eye
tre
atm
ent
104
H
RIP
T w
ith 1
50
µl t
est
ma
teria
l, se
mi-o
cclu
ded
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
14
3
1.9
9% O
enot
her
a B
ienn
is (
Eve
nin
g P
rimro
se)
Oil
in a
fo
un
datio
n 6
00
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
144
22%
Ole
a E
uro
pa
ea (
Oliv
e) F
ruit
Oil
in a
bod
y m
oist
uriz
er
105
H
RIP
T,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
14
5
58.
7% O
lea
Eu
rop
aea
(O
live)
Fru
it O
il in
a c
ondi
tioni
ng
hai
r oi
l 1
02
HR
IPT
with
0.2
ml,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
14
6
5%
Hyd
roge
na
ted
Oliv
e O
il U
nsa
pon
ifia
ble
s in
a s
kin
cl
ean
sin
g p
rodu
ct
57
HR
IPT
, se
mi-o
cclu
ded
, 10%
dilu
tion
not
a d
erm
al i
rrita
tion
or
sen
sitiz
er
135
2%
Hyd
roge
na
ted
Oliv
e O
il U
nsa
pon
ifia
ble
s in
a fa
ce
and
nec
k p
rodu
ct
50
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itatio
n o
r se
nsi
tizer
13
5
12%
Hyd
roge
na
ted
Oliv
e O
il in
a li
pst
ick
108
H
RIP
T,
occl
ud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
13
6
2.5
% O
lea
Eu
rop
aea
(O
live)
Oil
Un
sap
onfia
ble
s in
a
bat
h b
ody
mis
t 1
07
HR
IPT
with
15
0 µ
l tes
t m
ate
rial,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
14
7
CIR Panel Book Page 55
47
Tab
le 7
. Clin
ical
irrit
atio
n an
d se
nsiti
zatio
n st
udie
s on
veg
etab
le o
ils.
Ingr
edie
nt a
nd C
once
ntra
tion
Sub
ject
s C
ompl
eted
M
etho
d R
esul
ts
Ref
eren
ce
17.
64%
Sod
ium
Oliv
ate
in a
bod
y b
ar
soa
p 1
07
HR
IPT
, se
mi-o
cclu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
148
3.7
9% O
rbig
nya
Ole
ifera
Se
ed O
il in
a c
rea
m c
lea
nse
r 1
04
HR
IPT
with
0.2
ml o
f a 1
0% d
ilutio
n ,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
14
9
0.0
4% P
runu
s D
omes
tica
See
d O
il in
a p
resh
ave
lotio
n 1
05
HR
IPT
with
0.2
ml,
occl
uded
n
ot a
sen
sitiz
er
150
0.2
% R
ibes
Nig
rum
(B
lack
Cu
rra
nt)
See
d O
il is
an
eye
m
ask
2
28
HR
IPT
, oc
clu
ded
4 s
ubj
ects
ha
d "?
" or
"+
" re
act
ion
du
ring
indu
ctio
n th
at w
ere
not
co
nsi
der
ed c
linic
ally
re
leva
nt,
no
oth
er r
eact
ion
s ob
serv
ed.
Not
se
nsi
tizin
g 15
1
0.2
% R
ibes
Nig
rum
(B
lack
Cu
rra
nt)
See
d O
il is
an
eye
m
ask
1
95
4-w
eek
sa
fety
in-u
se s
tud
y
No
ad
vers
e re
act
ion
s re
por
ted
. P
rod
uct
con
sid
ered
sui
tab
le fo
r se
nsi
tive
skin
. 15
2
Rub
us
Ida
eus
(Ra
spb
erry
) S
eed
Oil
in a
face
and
nec
k p
rod
uct (
conc
entr
atio
n n
ot r
epor
ted
) 1
02
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itatio
n o
r se
nsi
tizer
13
5
0.0
023
% S
olan
um
Lyc
oper
sicu
m (
To
ma
to)
See
d O
il in
a
crea
m c
lea
nse
r 1
04
HR
IPT
with
0.2
ml o
f a 1
0% d
ilutio
n ,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
15
3
50.
1% T
heo
bro
ma
Ca
cao
(Coc
oa)
See
d B
utte
r in
a li
p
ba
lm
106
H
RIP
T w
ith 1
50
µl t
est
ma
teria
l, se
mi-o
cclu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
154
5%
Th
eob
rom
a G
rand
iflor
um
See
d B
utte
r in
a li
p b
alm
1
06
HR
IPT
with
15
0 µ
l tes
t m
ate
rial,
sem
i-occ
lud
ed
not
a d
erm
al i
rrita
nt o
r se
nsi
tizer
15
5
0.0
4% V
acci
nium
Ma
croc
arp
on (
Cra
nber
ry)
Se
ed O
il in
a
face
and
nec
k p
rodu
ct
53
HR
IPT
, oc
clu
ded
n
ot a
der
ma
l irr
itatio
n o
r se
nsi
tizer
13
5
4%
Veg
eta
ble
Oil
in a
foun
datio
n 1
15
HR
IPT
, se
mi-o
cclu
ded
1 s
ubj
ect h
ad
+ on
the
first
da
y of
th
e in
duc
tion
on
ly,
no
oth
er r
eact
ion
s. N
ot
ad
erm
al i
rrita
nt o
r se
nsi
tizer
. 15
6
4%
Veg
eta
ble
Oil
in a
lip
stic
k 1
06
HR
IPT
with
0.2
g, o
cclu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
157
11%
Veg
eta
ble
Oil
in a
n e
ye s
ha
dow
1
06
HR
IPT
, se
mi-o
cclu
ded
n
ot a
der
ma
l irr
itant
or
sen
sitiz
er
158
39%
Viti
s V
inife
ra (
Gra
pe
)See
d O
il in
a p
resh
ave
lotio
n 1
05
HR
IPT
with
0.2
ml,
occl
uded
n
ot a
sen
sitiz
er
150
0.5
% H
ydro
gen
ate
d G
rap
esee
d O
il in
a li
p p
rodu
ct
53
HR
IPT
, se
mi-o
cclu
ded
n
ot a
der
ma
l irr
itatio
n o
r se
nsi
tizer
15
9
CIR Panel Book Page 56
48
REFERENCES
1. Gottschalck TE and Bailey JE. International Cosmetic Ingredient Dictionary and Handbook. 2008. 12th:(3):Washington, DC: CTFA.
2. US Pharmacopeia. 2008-2009 Food Chemicals Codex. 6th ed. Baltimore: United Book Press, Inc., 2008.
3. Salunkhe, DK, Chavan, JK, Adsule, RN, and Kadam, SS. World Oilseeds: Chemistry, Technology, and Utilization. New York: Van Nostrand Reinhold, 1992.
4. Bailey's Industrial Oil & Fat Products. John Wiley & Sons., 1996.
5. John L. Seaton & Co, Ltd. Oil seed processing. Unpublished data. 2010.
6. Crevel, R. W., Kerkhoff, M. A., and Koning, M. M. Allergenicity of refined vegetable oils. Food Chem Toxicol. 2000;38:(4):385-393.
7. Andersen,F.A.(ed). Final report on the safety assessment of sesame oil. J Am coll Toxicol. 1993;12:(3):261-277.
8. Andersen,F.A.(ed). Final report on the safety assessment of Elaeis guineensis (palm) oil, Elaeis guineensis (palm) kernel oil, hydrogenated palm oil and hydrogenated palm kernel oil. Int J Toxicol. 2000;19:(Suppl 2):7-28.
9. Andersen,F.A.(ed). Final report on the safety assessment of peanut (arachis hypogaea) oil, hydrogenated peanut oil, peanut acid, peanut glycerides, and peanut (arachis hypogaea) flour. Int J Toxicol. 2001;20:(Suppl 2):65-77.
10. Andersen,F.A.(ed). Final report on the safety assessment of hydrogenated cottonseed oil cottonseed (Gossypium) oil, cottonseed acid, cottonseed glyceride, and hydrogenated cottonseed glyceride. Int J Toxicol. 2001;20:(Suppl 2):21-29.
11. Andersen,F.A.(ed). Amended final report on the safety assessment of Oryza sativa (rice) bran oil, Oryza sativa (rice)germ oil, rice bran acid, Oryza sative (rice)bran wax, hydrogenated rice bran wax, Oryza sativa (rice) bran extract, Oryza sativa (rice) extract, Oryza sative (rice) germ powder, Oryza sative (rice) starch, Oryza sativa (rice) bran, hydrolyzed rice bran extract, hydrolyzed rice bran protein, hydrolyzed rice extract. and hydrolyzed rice proten. Int J Toxicol. 2006;25:(Suppl 2):91-120.
12. Cosmetic Ingredient Review. Final report of the Cosmetic Ingredient Review Expert Panel. Amended safety assessment of cocos nucifera (coconut) oil, coconut acid, hydrogenated coconut acid, hydrogenated coconut oil, ammonium cocomonoglyceride sulfate, butylene glycol cocoate, carprylic/capric/coco glycerides, cocoglycerides, coconut alcohol, coconut oil decyl esters, decyl cocoate, ethylhexyl cocoate, hydrogenated coco-glycerides, isodecyl cocoate, lauryl cocoate, magnesium cocoate, methyl cocoate, octyldodecyl cocoate, pentaerythrityl cocoate, potassium cocoate, potassium hydrogenated cocoate, sodium cocoate, sodium cocomonoglyceride sulfate, sodium hydrogenated cocoate, adn tridecyl cocoate. Available from CIR. 2008.
13. Elder,R.L.(ed.). Final report on the safety assessment for wheat germ oil. JEPT. 1980;4:(4):33-45.
14. Elder,R.L.(ed.). Final report of the safety assessment for avocado oil. JEPT. 1980;4:(4):93-103.
15. Elder,R.L.(ed.). Final report on the safety assessment of safflower oil. J Am coll Toxicol. 1985;4:(5):171-197.
16. Halsey, A. B., Martin, M. E., Ruff, M. E., Jacobs, F. O., and Jacobs, R. L. Sunflower oil is not allergenic to sunflower seed-sensitive patients. J Allergy Clin Immunol. 1986;78:408-410.
17. Zitouni, N., Errahali, Y., Metche, M., Kanny, G., Moneret-Vautrin, D. A., Nicolas, J. P., and Fremont, S. Influence of refining steps on trace allergenic protein content in sunflower oil. J Allergy Clin Immunol. 2000;106:(5):962-967.
CIR Panel Book Page 57
49
18. Olszewski, A, Pons, L, Moutété, F, Aimone-Gastin, I, Kanny, G, Moneret-Vautrin, DA, and Gueant, JL. Isolation and characterization of proteic allergens in refined peanut oil. Clin Exp Allergy. 1998;28:850-859.
19. Ramazzotti, M., Mulinacci, N., Pazzagli, L., Moriondo, M., Manao, G., Vincieri, F. F., and Degl'Innocenti, D. Analytic investigations on protein content in refined seed oils: implications in food allergy. Food Chem Toxicol. 2008;46:(11):3383-3388.
20. Porras, O., Carlsson, B., Fallstrom, S. P., and Hanson, L. A. Detection of soy protein in soy lecithin margarine and, occasionally, soy oil. Int Archs Allergy Appl Immunol. 1985;78:30-32.
21. Awazuhara, H., Kawai, H., Baba, M., Matsui, T., and Komiyama, A. Antigenicity of the proteins in soy lecithin and soy oil in soybean allergy. Clin Exp Allergy. 1998;28:1559-1564.
22. Paschke, A, Zunker K, Wigotzki M, and Steinhart H. Determination of the IgE-binding activity of soy lecithin and refined and non-refined soybean oils. J Chromatogr B. 2001;(756):249-254.
23. European Medicines Agency (EMEA). Working party on herbal medicinal products. Final position paper on the allergenic potency of herbal medicinal products containing soya or peanut protein. EMEA/HMPWP/37/04. http://www.ema.europa.eu/pdfs/human/hmpc/003704en.pdf. 6-11-2004.
24. Food and Drug Administration (FDA). Frequency of use of cosmetic ingredients. FDA database. 5-4-2010.
25. Personal Care Products Council. Concentration of use - Plant Oils. March 2010 Survey. Unpublished data submitted by the Council (27 pp). 5-13-2010.
26. Personal Care Products Council. Concentration of use - Plant Oils. Updated May 2010 survey. Unpublished data submitted by the Council (10 pp). 7-21-2010.
27. Andersen, FA. Annual Review of Cosmetic Ingredient Safety Assessments - 2001/2002. IJT. 2003;22:(Suppl. 1):1-35.
28. Diamante, CD, Andersen, FA, and Cosmetic Ingredient Review Expert Panel. Safety Assessment of Zea Mays (Corn) Oil, et al. 2008.
29. Elder, RL. Final Report of the Safety Assessment for Wheat Germ Oil. JEPT. 1980;4:(4):33-45.
30. Johnson, WJ, Andersen, FA, and Cosmetic Ingredient Review Expert Panel. Amended Safety Assessment of Sesamum Indicum (Sesame) Seed Oil, Hydrogenated Sesame Seed Oil, Sesamm Indicum (Sesame) Oil Unsaponifiables, and Sodium Sesameseedate. 2009.
31. James, A. C., Stahlhofen, W, Rudolf, G, Kobrich, R, Briant, J. K., Egan, M. J., Nixon, W, and Birchall, A. Annexe D. Deposition of inhaled particles. Annals of the ICRP. 1994;24:(1-3):231-2.
32. Oberdorster, G, Oberdorster, E, and Oberdorster, J. Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles. Environmental Health Perspectives. 2005;113:(7):823-839.
33. Bower, D. 1999. Unpublished information on hair spray particle sizes provided at the September 9, 1999 CIR Expert Panel meeting.
34. Johnson, M. A. The Influence of Particle Size. Spray Technology and Marketing. 2004;November:24-27.
35. European Union. 1976, Council Directive 1976/768/EEC of 27 July 1976 on the Approximation of the Laws of the Member States Relating to Cosmetic Products, as amended through Commission Directive 2008/42/EC. 2008.
36. American Soybean Association.Soy Stats 2010 - World Vegetable Oil Consumption 2009. 2010. http://www.soystats.com/2010/Default-frames.htm. Accessed 4-14-2010.
CIR Panel Book Page 58
50
37. MB Research Laboratories. MatTek EpiOcular MTT Viability Assay of Baobab Oil. MB Research Project #: MB 08-17549.19. Unpublished data. 2008. MB Research Laboratories.
38. Grover, R. W. Experimental contact sensitization of guinea pigs to vegetable oils. J Allergy. 1962;33:(5):402-405.
39. ICCVAM Immunotoxicology Working Group.Protocol: Murine local lymph node assay (LLNA). 2001. http://iccvam.niehs.nih.gov/docs/immunotox_docs/llna/LLNAProt.pdf. Accessed 5-27-2010.
40. Cell Toxicology Laboratory. Assessment of the eye irritaing potential of a cosmetic product through alternative methods to the Draize test. Report reference: CTOX/08059. Unpublished data. 9-11-2008.
41. Said, T., Dutot, M., Christon, R., Beaudeux, J. L., Martin, C., Warnet, J.-M., and Rat, P. Benefits and side effects of different vegetable oil vectors on apoptosis, oxidative stress, and P2X7 cell death receptor activation. Invest Ophthalmol Vis.Sci. 2007;48:5000-5006.
42. CPTC. Hen's egg tst - chorioallantoic membrane (HET-CAM) of a 50% dilution of an eye mask containing 0.2% Ribes Nigrum (Black Currant) Seed Oil. HET-CAM 07-7331-038. Unpublished data (summary). 2007.
43. IARC. Glycidol. 2000. IARC Monographs:(77):469-486.
44. IARC. Epoxides. 1976. IARC Monographs:(11):125-209.
45. Federal Institute for Risk Assessment. Initial evaluation ofhte assessment of levels of glycidol fatty acid esters detected in refined vegetable fats--B&R opinion no. 007/2009. 2009. http://www.bfr.bund.de./cm/245/initial_evaluation_of_the_assessment_of glycidol_fatty_acid_esters.pdf. Date Accessed 3-10-2009.
46. Weisshauer R. Fatty acid esters of 3-MCPD: overview of occurences in different types of foods. Chemisches und Veterinaruntersuchungsaut (CUUA). 2009. http://www.ilsi.org/Europe/Documents/E2009MCPD-7.pdf.
47. de Groot AC. Adverse Reactions to Cosmetics. Port Washington, NY: Scholium International, Inc, 1988.
48. Bush, R. K., Taylor, S. L., Nordlee, J. A., and Busse, W. W. Soybean oil is not allergenic to soybean-sensitive individuals. J Allergy Clin Immunol. 1985;76:(2 PART 1):242-245.
49. Clinical Research Laboratories, Inc. An in-use safety evaluation to determine the ocular irriation potential of a cosmetic product. CRL study number: CRL 135208. Unpublished data. 1-12-2009.
50. IRSI. 4-week use study of an eye mask containing 0.2% Ribes Nigrum (Black Currant) Seed Oil. Ophth 07-7331-050. Unpublished data (summary). 2007.
51. Ivy Labs (KGL). Comedogenicity study of an eye mak containing 0.2% Ribes Nigrum (Black Currant) Seed Oil. Comedo 07-7331-039. Unpublished data (summary). 2007.
52. Kanny, G., Fremont, S., Nicolas, J. P., and Moneret-Vautrin, D. A. Food allergy to sunflower oil in a patient sensitized to mugwort pollen. Allergy. 1994;49:561-564.
53. van Joost T., Smitt, J. H., and van Ketel, W. G. Sensitization to olive oil (olea europeae). Contact Dermatitis. 1981;7:(6):309-310.
54. de Boer, E. M. and van Ketel, W. G. Contact allergy to an olive oil containing ointment. Contact Dermatitis. 1984;11:(2):128-129.
55. Jung, H. D. and Holzegel, K. [Contact allergy to olive oil]. Derm Beruf.Umwelt. 1987;35:(4):131-133.
56. Malmkvist Padoan S., Pettersson, A., and Svensson, A. Olive oil as a cause of contact allergy in patients with venous eczema, and occupationally. Contact Dermatitis. 1990;23:(2):73-76.
CIR Panel Book Page 59
51
57. Isaksson, M. and Bruze, M. Occupational allergic contact dermatitis from olive oil in a masseur. J Am Acad Dermatol. 1999;41:(2 Pt 2):312-315.
58. Wong, G. A. and King, C. M. Occupational allergic contact dermatitis from olive oil in pizza making. Contact Dermatitis. 2004;50:(2):102-103.
59. Williams, J. D. and Tate, B. J. Occupational allergic contact dermatitis from olive oil. Contact Dermatitis. 2006;55:(4):251-252.
60. Beukers, S. M., Rustemeyer, T., and Bruynzeel, D. P. Cheilitis due to olive oil. Contact Dermatitis. 2008;59:(4):253-255.
61. Kranke, B., Komericki, P., and Aberer, W. Olive oil--contact sensitizer or irritant? Contact Dermatitis. 1997;36:(1):5-10.
62. Zipprich, F. and Hauser, C. Olive oil--contact sensitizer or irritant? Contact Dermatitis. 1997;37:(3):142-143.
63. de Groot, A. C., van der Meeren, H. L., and Weyland, J. W. Contact allergy to avocado oil in a sunscreen. Contact Dermatitis. 1987;16:(2):108-109.
64. Oiso, N., Yamadori, Y., Higashimori, N., Kawara, S., and Kawada, A. Allergic contact dermatitis caused by sesame oil in a topical Chinese medicine, shi-un-ko. Contact Dermatitis. 2008;58:(2):109.
65. John L. Seaton & Co, Ltd. Seatons Maize Oil data sheet. 2007. John L. Seaton & Co., Ltd.
66. John L. Seaton & Co, Ltd. Seatons Refined Maize Oil specifications. 2009. John L. Seaton & Co., Ltd.
67. Andersen, FA. Annual Review of Cosmetic Ingredient Safety Assessments-2004/2005. IJT. 2006;25:(Suppl. 2):1-89.
68. Enlightened Products Co.Analytical Study on Life Dynamics Acai - Part 1. 2010. http://www.enlightenedproductsco.com/Pages/acai/aslda1.html. Accessed 1-25-2010.
69. Aroma Plus, Dr. Hoffmann Ingredients Corp.Amaranth Oil - Data Sheet. 2010. http://www.aromaplus.de/1Amaranth%20oil.htm. Accessed 1-25-2010.
70. BDpedia.Plant Oils Used for Bio-diesel. 2006. http://www.bdpedia.com/biodiesel/plant_oils/plant_oils.html. Accessed 1-25-2010.
71. Center for New Crops & Plant Products.Moringa oleifera Lam. 1-7-1998. http://www.hort.purdue.edu/newcrop/duke_energy/Moringa_oleifera.html. Accessed 1-25-2010.
72. Putnam, DH, Budin, JT, Field, LA, and Breene, WM.Camelina: A promising low-input oilseed. 9-11-1997. http://www.hort.purdue.edu/newcrop/proceedings1993/v2-314.html. Accessed 1-26-2010.
73. Natural Sourcing.Cranberry Seed Oil Specifications. 2008. http://www.naturalsourcing.com/spec/SPEC_Cranberry_Seed_Oil.pdf. Accessed 1-28-2010.
74. Natural Sourcing.Cucumber Seed Oil. 2010. http://www.naturalsourcing.com/downloads/NS_info_cucumberseedoil.pdf. Accessed 1-28-2010.
75. Natural Sourcing.Cupuacu Butter. 2009. http://www.naturalsourcing.com/product.asp?product_id=vegbuttercupuacu&cat=AmazonianOils. Accessed 1-27-2010.
76. Marula Natural Products.Marula Natural Products: Technical Info - Oil. 2010. http://www.marula.org.za/techoil.htm. Accessed 1-26-2010.
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52
77. Natural Sourcing.Murumuru Butter Specifications. 2008. http://www.naturalsourcing.com/spec/SPEC_Murumuru_Butter.pdf. Accessed 1-27-2010.
78. Northstar Lipids.Product Specification. 2010. http://www.northstarlipids.co.uk/files/peach-kernel-oil.pdf. Accessed 1-28-2010.
79. Koziol, MJ.Quinoa: A Potential New Oil Crop. 1997. Accessed 1-26-2010.
80. Natural Sourcing.Strawberry Seed Oil Specifications. 2008. http://www.naturalsourcing.com/spec/SPEC_Strawberry_Seed_Oil.pdf. Accessed 1-28-2010.
81. Natural Sourcing.Watermelon Seed Oil Specifications. 2009. http://www.naturalsourcing.com/spec/SPEC_Watermelon_Seed_Oil.pdf.
82. John L. Seaton & Co, Ltd. Seatons Baobab Oil data sheet. Unpublished data. 2005. John L. Seaton & Co, Lted.
83. John L. Seaton & Co, Ltd. Seatons Refined Baobab Oil specifications. Unpublished data. 2009. John L. Seaton & Co., Ltd.
84. John L. Seaton & Co, Ltd. Seatons Rice Bran Oil data sheet. 2005. John L. Seaton & Co, Ltd.
85. John L. Seaton & Co, Ltd. Seatons Cherry Kernel Oil data sheet. 2005. John L. Seaton & Co. Ltd.
86. John L. Seaton & Co, Ltd. Seatons Refined Cherry Kernel Oil specifications. 2009. John L. Seaton & Co., Ltd.
87. John L. Seaton & Co, Ltd. Seatons Argan Oil data sheet. 2005. John L. Seaton & Co., Ltd.
88. John L. Seaton & Co, Ltd. Seatons Virgin Argan Oil specifications. 2009. John L. Seaton & Co., Ltd.
89. John L. Seaton & Co, Ltd. Seatons Borage Oil data sheet. 2005. John L. Seaton & Co., Ltd.
90. John L. Seaton & Co, Ltd. Seatons Refined Borage Oil specifications. 2009. John L. Seaton & Co., Ltd.
91. John L. Seaton & Co, Ltd. Seatons Camellia Seed Oil data sheet. 2007. John L. Seaton & Co, Ltd.
92. John L. Seaton & Co, Ltd. Seatons Camellia Seed Oil specifications. 2005. John L. Seaton & Co., Ltd.
93. John L. Seaton & Co, Ltd. Seatons Papaya Seed Oil data sheet. 2005. John L. Seaton & Co., Ltd.
94. John L. Seaton & Co, Ltd. Seatons Refined Papaya Seed Oil specification. 2010. John L. Seaton & Co., Ltd.
95. John L. Seaton & Co, Ltd. Seatons Lime Seed Oil data sheet. 2007. John L. Seaton & Co., Ltd.
96. John L. Seaton & Co, Ltd. Seatons Refined Lime Seed Oil specifications. 2007. John L. Seaton & Co., Ltd.
97. John L. Seaton & Co, Ltd. Seatons Orange Seed Oil data sheet. 2009. John L. Seaton & Co., Ltd.
98. John L. Seaton & Co, Ltd. Seatons Refined Orange Seed Oil specifications. 2009. John L. Seaton & Co., Ltd.
99. John L. Seaton & Co, Ltd. Seatons Grapefruit Seed Oil data sheet. 2007. John L. Seaton & Co., Ltd.
100. John L. Seaton & Co, Ltd. Seatons Refined Grapefruit Seed Oil specifications. 2010. John L. Seaton & Co., Ltd.
101. John L. Seaton & Co, Ltd. Seatons Pumpkin Seed Oil data sheet. 2007. John L. Seaton & Co., Ltd.
102. John L. Seaton & Co, Ltd. Seatons Pressed Pumpkin Seed Oil specifications. 2006. John L. Seaton & Co., Ltd.
103. John L. Seaton & Co, Ltd. Seatons Cranberry Seed Oil data sheet. 2005. John L. Seaton & Co., Ltd.
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104. John L. Seaton & Co, Ltd. Seatons Refined Cranberry Seed Oil specification. 2008. John L. Seaton & Co., Ltd.
105. John L. Seaton & Co, Ltd. Seatons Evening Primrose Oil data sheet. 2005. John L. Seaton & Co., Ltd.
106. John L. Seaton & Co, Ltd. Seatons Refined Evening Primose Oil specification. 2009. John L. Seaton & Co., Ltd.
107. John L. Seaton & Co, Ltd. Seatons Plum Oil data sheet. 2005. John L. Seaton & Co., Ltd.
108. John L. Seaton & Co, Ltd. Seatons Virgin Plum Oil specification. 2010. John L. Seaton & Co., Ltd.
109. John L. Seaton & Co, Ltd. Seatons Blackcurrant Seed Oil specification. 2005. John L. Seaton & Co., Ltd.
110. John L. Seaton & Co, Ltd. Seatons Refined Blackcurrant Seed Oil specification. 2010. John L. Seaton & Co., Ltd.
111. John L. Seaton & Co, Ltd. Seatons Red Raspberry Seed Oil data sheet. 2007. John L. Seaton & Co., Ltd.
112. John L. Seaton & Co, Ltd. Seatons Refined Red Raspberry Seed Oil specification. 2006. John L. Seaton & Co., Ltd.
113. John L. Seaton & Co, Ltd. Seatons Moringa Oil data sheet. 2005. John L. Seaton & Co., Ltd.
114. John L. Seaton & Co, Ltd. Seatons Refined Moringa Oil specification. 2006. John L. Seaton & Co., Ltd.
115. John L. Seaton & Co, Ltd. Seatons Refined Rice Bran Oil specifications. 2009. John L. Seaton & Co, Ltd.
116. Consumer Product Testing Co. Repeated insult patch test of a lip product containing 0.01% Adansonia Digitata Seed Oil. Experiment reference number: C08-1131.02. Unpublished data. 4-29-2008.
117. BioScreen Testing Services, Inc. Human subject repeat insult patch test skin irritation/sensitization evaluation of Phytoterra Organic Baobab Oil. SCS Study No.: 08-042. 2009. BioScreen Testing Services, Inc.
118. Product Investigations, Inc. Determination of the irritating and sensitizing propensities of lipstick (containing 1% Astrocaryum Murumuru Seed Butter) on human skin. Unpublished data. 9-30-2002. Product Investigations, Inc.
119. Clinical Research Laboratories, Inc. Repeated insult patch test on a lipstick formulation containing 4% Astrocaryum Murumura Seed Butter. CRL study no.: CRL69608-4. Unpublished data. 8-1-2008.
120. Clinical Research Laboratories, Inc. Repeated insult patch test on a lipstick formulation containing 4% Astrocaryum Murumura Seed Butter. CRL study no.: CRL69608-5. Unpublished data. 8-1-2008.
121. Clinical Research Laboratories, Inc. Repeated insult patch test on a lipstick formulation containing 4% Astrocaryum Murumura Seed Butter. CRL study no.: CRL69608-6. Unpublished data. 8-1-2008.
122. Clinical Research Laboratories, Inc. Repeated insult patch test on a lipstick formulation containing 4% Astrocaryum Murumura Seed Butter. CRL study no.: CRL109108-1. Unpublished data. 11-11-2008.
123. Clinical Research Laboratories, Inc. Repeated insult patch test on a lipstick formulation containing 4% Astrocaryum Murumura Seed Butter. CRL study no.: CRL109108-2. Unpublished data. 8-1-2008.
124. Clinical Research Laboratories, Inc. Repeated insult patch test on a lipstick formulation containing 4% Astrocaryum Murumura Seed Butter. CRL study no.: CRL114608-6. Unpublished data. 11-21-2008.
125. RCTS, Inc. Clinical safety evaluation. Human repeated insult patch test with a body and hand formulation containing 3% Avena Sativa (Oat) Kernel Oil. RCTS study no.: 1712 &1714. Unpublished data. 9-8-2004.
126. TKL Research. Repeated insult patch test on a body and hand formulation containng 1% Borago Officinalis Seed Oil. TKL study o.: DS103107/103507. 6-22-2007.
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127. Consumer Product Testing Co. Repeated insult patch test of a baby oil containing 5% hydrogenated rapeseed oil. Unpublished data. 1999.
128. Product Investigations, Inc. Determination of the irritating and sensitizing propensities of a hair conditioner (containing 0.5% Brassica Oleracea Italica (Broccoli) Seed Oil) on human skin. Unpublished data. 11-11-2008. Product Investigations, Inc.
129. Consumer Product Testing Co. Repeated insult patch test on a lipstick containing 0.0985% Camellia Sinensis Seed Oil. Ref. No.: C08-5394.07. 2008.
130. Consumer Product Testing Co. Repeated insult parch test of a lipstick containing 0.0985% Camellia Sinensis Seed OIl. Ref. No. C08-5394.08. 2008.
131. Product Investigations, Inc. Determination of the irritating and sensitizing propensities of a body oil (containing 74.7% Canola Oil) on human skin. Unpublished data. 2005. Product Investigations, Inc.
132. Product Investigations, Inc. Determination of the irritating and sensitizing propensities of a lipstick (containing 0.1% Caryocar Brasilienses Fruit Oil) on human skin. Unpublished data. 2009. Products Investigations, Inc.
133. Clinical Research Laboratories, Inc. Repeated insult patch test of a facial oil containing 2% Citrullus Lanatus (Watermelono) Seed Oil. Unpublished data. 2009. Clinical Research Laboratories, Inc.
134. Product Investigations, Inc. Determination of the irritating and senstizing propensities of an eye treatment (containing 0.5% Euterpe Oleracea Fruit Oil) on human skin. Unpublished data. 2007. Product Investigations, Inc.
135. Personal Care Products Council. Summaries of HRIPT studies of products containing plant oils. Unpublished data. 6-1-2010.
136. Clinical Research Laboratories, Inc. Repeated insult patch test on a lipstick containing 39% Hydrogenated Soybean Oil and 12% Hydrogenated Olive Oil. CRL study no.: CRL128208-13. Unpublished data. 12-24-2008.
137. Clinical Research Laboratories, Inc. Repeated insult patch test of a facial repair product containing 71.3% Limnanthes Alba (Meadowfoam) Seed Oil. Unpublished data. 2005. Clinical Research Laboratories, Inc.
138. Consumer Product Testing Co. Repeated insult patch test on a mascara containing Linum Usitatissiumum (Linseed) Seed Oil at 9.4%. Experiment reference number: C08-3409.02. Unpublished data. 9-10-2008.
139. Consumer Product Testing Co. Repeated insult patch test protocol of an eyeliner containing 3.87% Mangifera Indica (Mango) Seed Oil. Unpublished data. 2004. Consumer Product Testing Co.
140. Product Investigations, Inc. Determination of the irritating and sensitizing propensities of lipstick (containing 2% Mangifera Indica (Mango) Seed Oil) on human skin. Unpublished data. 2003. Product Investigations, Inc.
141. TKL Research. Repeated insult patch test of a body product containing 9% Mangifera Indican (Mango) Seed Butter. Unpublished data. 2001.
142. Product Investigations, Inc. Determination of the irritating and sensitizing propensities of a facial lotion (containing 1% Mangifera Indica (Mango) Seed Butter) on human skin. Unpublished data. 2009. Product Investigations, Inc.
143. Product Investigations, Inc. Determination of the irritating and sensitizing propensities of an eye treatment (containing 3% Moringa Pterygosperm Seed Oil) on human skin. Unpublished data. 2007. Product Investigations, Inc.
144. Orentreich Research Corporation. Predictive patch test study of a foundation containing 1.99% Oenothera Biennis (Evening Primrose) Oil. Unpublished data. 2007.
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55
145. Clinical Research Laboratories, Inc. Repeated insult patch test on a body moisturizer containing 22% Olea Europaea (Olive) Fruit Oil. Unpublished data. 2007.
146. Consumer Product Testing Co. Repeated insult patch test on a conditioning hair oil containing 58.70% Olea Europaea (Olive) Fruit Oil. Unpublished data. 2003.
147. Product Investigations, Inc. Determination of the irritating and sensitizing propensities on human skin for a frgranced body mist containing 2.5% Olea Europaea (Olive) Oil Unsaponifiables. Unpublished data. 2007.
148. Clinical Research Laboratories, Inc. Repeated insult patch test of a body bar soap containng 17.64% sodium olivate. Unpublished data. 2008.
149. Consumer Product Testing Co. Repeated insult patch test of a cream cleanser containing 3.79% Orbignya Oleifera Seed Oil. Unpublished data. 2006. Consumer Product Testing Co.
150. TKL Research. Repeated insult patch test of a preshave lotion containing 39% Vitis Vinifera (Grape) Seed Oil and 0.04% Prunus Domestica Seed Oil. TKL Study No: DS109206-3. Unpublished data. 2-15-2007.
151. TKL Reseach. HRIPT of an eye mask containing 0.2% Ribes Nigrum (Black Currant) Seed Oil. RIPT 07-7331-036. Unpublished data (summary). 2007.
152. Q Research. 4-week use study of an eye mask containing 0.2% Ribes Nigrum (Black Currant) Seed Oil. Use 07-7331-056. Unpublished data (summary). 2007.
153. Consumer Product Testing Co. Repeated insult patch test of a cream cleanser containing 0.0023% Solanum Lycopersicum (Tomato) Seed Oil. Unpublished data. 2006. Consumer Product Testing, Co.
154. Product Investigations, Inc. Determination of the irritating and sensitizing propensities of a lip balm (containing 50.1% Theobroma Cacao (Cocoa) Seed Butter) on human skin. Unpublished data. 2006. Product Investigations, Inc.
155. Product Investigations, Inc. Determination of the irritating and sensitizing propensities of a lip balm (containing 5% Theobroma Grandiflorum Seed Butter) on human skin. Unpublished data. 2008. Product Investigations, Inc.
156. Clinical Research Laboratories, Inc. Repeated insult patch test of a foundation containing 4% Vegetable Oil. Unpublished data. 2005. Clinical Research Laboratories, Inc.
157. Consumer Product Testing Co. Exclusive repeated insult patchtest on a lipstick containing 4% vegetable oil. Ref. No. C07-0193.12. Unpublished data. 2007.
158. Clinical Research Laboratories, Inc. Repeated insult patch test of an eye shadow containing 11% vegetable oil. CRL study number: CRL14606-4. Unpublished data. 3-30-2006.
159. Clinical Research Laboratories, Inc. Repeated insult patch test of a lip product containing 0.5% hydrogenated grapeseed oil. CRL study number: CRL88908-5. Unpublished data. 9-8-2008.
CIR Panel Book Page 64
Data
CIR Panel Book Page 65
2010 FDA VCRP Raw Data
VEGETABLE FATTY ACID 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 17
VEGETABLE FATTY ACID 07E - Lipstick 3
VEGETABLE FATTY ACID 12F - Moisturizing 1
VEGETABLE OIL 01B - Baby Lotions, Oils, Powders, and Creams 1
VEGETABLE OIL 02A - Bath Oils, Tablets, and Salts 1
VEGETABLE OIL 02D - Other Bath Preparations 1
VEGETABLE OIL 03C - Eye Shadow 1
VEGETABLE OIL 03D - Eye Lotion 1
VEGETABLE OIL 03F - Mascara 2
VEGETABLE OIL 03G - Other Eye Makeup Preparations 7
VEGETABLE OIL 04E - Other Fragrance Preparation 1
VEGETABLE OIL 05F - Shampoos (non-coloring) 1
VEGETABLE OIL 06H - Other Hair Coloring Preparation 1
VEGETABLE OIL 07C - Foundations 3
VEGETABLE OIL 07E - Lipstick 71
VEGETABLE OIL 07I - Other Makeup Preparations 6
VEGETABLE OIL 08C - Nail Creams and Lotions 1
VEGETABLE OIL 10A - Bath Soaps and Detergents 1
VEGETABLE OIL 12A - Cleansing 5
VEGETABLE OIL 12C - Face and Neck (exc shave) 5
VEGETABLE OIL 12D - Body and Hand (exc shave) 7
VEGETABLE OIL 12F - Moisturizing 8
VEGETABLE OIL 12G - Night 4
VEGETABLE OIL 12H - Paste Masks (mud packs) 3
VEGETABLE OIL 12J - Other Skin Care Preps 10
VEGETABLE OIL 13A - Suntan Gels, Creams, and Liquids 3
HYDROGENATED VEGETABLE OIL 03A - Eyebrow Pencil 29
HYDROGENATED VEGETABLE OIL 03B - Eyeliner 38
HYDROGENATED VEGETABLE OIL 03C - Eye Shadow 11
HYDROGENATED VEGETABLE OIL 03D - Eye Lotion 9
HYDROGENATED VEGETABLE OIL 03F - Mascara 4
HYDROGENATED VEGETABLE OIL 03G - Other Eye Makeup Preparations 11
HYDROGENATED VEGETABLE OIL 04E - Other Fragrance Preparation 1
HYDROGENATED VEGETABLE OIL 05A - Hair Conditioner 2
HYDROGENATED VEGETABLE OIL 07B - Face Powders 1
HYDROGENATED VEGETABLE OIL 07C - Foundations 8
HYDROGENATED VEGETABLE OIL 07E - Lipstick 216
HYDROGENATED VEGETABLE OIL 07I - Other Makeup Preparations 27
HYDROGENATED VEGETABLE OIL 08B - Cuticle Softeners 1
HYDROGENATED VEGETABLE OIL 10A - Bath Soaps and Detergents 1
HYDROGENATED VEGETABLE OIL 10E - Other Personal Cleanliness Products 1
HYDROGENATED VEGETABLE OIL 12A - Cleansing 12
HYDROGENATED VEGETABLE OIL 12C - Face and Neck (exc shave) 7
HYDROGENATED VEGETABLE OIL 12D - Body and Hand (exc shave) 21
HYDROGENATED VEGETABLE OIL 12E - Foot Powders and Sprays 1
HYDROGENATED VEGETABLE OIL 12F - Moisturizing 30
HYDROGENATED VEGETABLE OIL 12G - Night 7
HYDROGENATED VEGETABLE OIL 12H - Paste Masks (mud packs) 2
HYDROGENATED VEGETABLE OIL 12J - Other Skin Care Preps 15
HYDROGENATED VEGETABLE OIL 13B - Indoor Tanning Preparations 1
HYDROGENATED VEGETABLE OIL 13C - Other Suntan Preparations 1
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 03D - Eye Lotion 1
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 03G - Other Eye Makeup Preparations 1
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 07E - Lipstick 1
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 10E - Other Personal Cleanliness Products 1
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12A - Cleansing 3
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12C - Face and Neck (exc shave) 4
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12D - Body and Hand (exc shave) 9
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12F - Moisturizing 3
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12G - Night 1
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12J - Other Skin Care Preps 1
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 13B - Indoor Tanning Preparations 2
CIR Panel Book Page 66
2010 FDA VCRP Raw Data
HYDROGENATED RAPESEED OIL 12A - Cleansing 1
CANOLA OIL 02A - Bath Oils, Tablets, and Salts 1
CANOLA OIL 03B - Eyeliner 1
CANOLA OIL 03C - Eye Shadow 1
CANOLA OIL 03D - Eye Lotion 1
CANOLA OIL 05A - Hair Conditioner 6
CANOLA OIL 05F - Shampoos (non-coloring) 2
CANOLA OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 7
CANOLA OIL 05I - Other Hair Preparations 4
CANOLA OIL 07E - Lipstick 62
CANOLA OIL 07I - Other Makeup Preparations 4
CANOLA OIL 10A - Bath Soaps and Detergents 2
CANOLA OIL 11G - Other Shaving Preparation Products 1
CANOLA OIL 12A - Cleansing 4
CANOLA OIL 12D - Body and Hand (exc shave) 13
CANOLA OIL 12E - Foot Powders and Sprays 1
CANOLA OIL 12F - Moisturizing 15
CANOLA OIL 12G - Night 2
CANOLA OIL 12J - Other Skin Care Preps 5
HYDROGENATED CANOLA OIL 12A - Cleansing 1
HYDROGENATED CANOLA OIL 12J - Other Skin Care Preps 2
PALM KERNEL ACID 04E - Other Fragrance Preparation 1
PALM KERNEL ACID 05F - Shampoos (non-coloring) 1
PALM KERNEL ACID 10A - Bath Soaps and Detergents 61
PALM KERNEL ACID 10E - Other Personal Cleanliness Products 3
PALM KERNEL ACID 11F - Shaving Soap 2
PALM KERNEL ACID 12A - Cleansing 2
PALM KERNEL ACID 12I - Skin Fresheners 2
ELAEIS OLEIFERA KERNEL OIL 05E - Rinses (non-coloring) 1
ELAEIS OLEIFERA KERNEL OIL 05I - Other Hair Preparations 1
ELAEIS OLEIFERA KERNEL OIL 06H - Other Hair Coloring Preparation 3
PALM ACID 04E - Other Fragrance Preparation 1
PALM ACID 10A - Bath Soaps and Detergents 31
PALM ACID 12A - Cleansing 1
PALM FATTY ACID 10A - Bath Soaps and Detergents 27
PALM FATTY ACID 12A - Cleansing 2
POTASSIUM PALMATE 10A - Bath Soaps and Detergents 2
POTASSIUM PALMATE 11F - Shaving Soap 3
POTASSIUM PALM KERNELATE 10A - Bath Soaps and Detergents 1
POTASSIUM PALM KERNELATE 10E - Other Personal Cleanliness Products 3
POTASSIUM PALM KERNELATE 11F - Shaving Soap 3
SODIUM PALMATE 01C - Other Baby Products 3
SODIUM PALMATE 02D - Other Bath Preparations 1
SODIUM PALMATE 04E - Other Fragrance Preparation 1
SODIUM PALMATE 10A - Bath Soaps and Detergents 184
SODIUM PALMATE 10E - Other Personal Cleanliness Products 5
CIR Panel Book Page 67
2010 FDA VCRP Raw Data
SODIUM PALMATE 11F - Shaving Soap 5
SODIUM PALMATE 12A - Cleansing 10
SODIUM PALMATE 12C - Face and Neck (exc shave) 2
SODIUM PALMATE 12H - Paste Masks (mud packs) 1
SODIUM PALM KERNELATE 01C - Other Baby Products 4
SODIUM PALM KERNELATE 02D - Other Bath Preparations 3
SODIUM PALM KERNELATE 04E - Other Fragrance Preparation 1
SODIUM PALM KERNELATE 10A - Bath Soaps and Detergents 169
SODIUM PALM KERNELATE 10E - Other Personal Cleanliness Products 4
SODIUM PALM KERNELATE 11A - Aftershave Lotion 1
SODIUM PALM KERNELATE 11F - Shaving Soap 3
SODIUM PALM KERNELATE 12A - Cleansing 5
SODIUM PALM KERNELATE 12J - Other Skin Care Preps 4
GLYCINE SOJA (SOYBEAN) OIL 01A - Baby Shampoos 1
GLYCINE SOJA (SOYBEAN) OIL 01B - Baby Lotions, Oils, Powders, and Creams 17
GLYCINE SOJA (SOYBEAN) OIL 01C - Other Baby Products 3
GLYCINE SOJA (SOYBEAN) OIL 02A - Bath Oils, Tablets, and Salts 13
GLYCINE SOJA (SOYBEAN) OIL 02B - Bubble Baths 1
GLYCINE SOJA (SOYBEAN) OIL 02D - Other Bath Preparations 5
GLYCINE SOJA (SOYBEAN) OIL 03B - Eyeliner 7
GLYCINE SOJA (SOYBEAN) OIL 03C - Eye Shadow 20
GLYCINE SOJA (SOYBEAN) OIL 03D - Eye Lotion 13
GLYCINE SOJA (SOYBEAN) OIL 03E - Eye Makeup Remover 2
GLYCINE SOJA (SOYBEAN) OIL 03F - Mascara 3
GLYCINE SOJA (SOYBEAN) OIL 03G - Other Eye Makeup Preparations 8
GLYCINE SOJA (SOYBEAN) OIL 04E - Other Fragrance Preparation 3
GLYCINE SOJA (SOYBEAN) OIL 05A - Hair Conditioner 25
GLYCINE SOJA (SOYBEAN) OIL 05B - Hair Spray (aerosol fixatives) 2
GLYCINE SOJA (SOYBEAN) OIL 05F - Shampoos (non-coloring) 19
GLYCINE SOJA (SOYBEAN) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 23
GLYCINE SOJA (SOYBEAN) OIL 05H - Wave Sets 1
GLYCINE SOJA (SOYBEAN) OIL 05I - Other Hair Preparations 27
GLYCINE SOJA (SOYBEAN) OIL 06C - Hair Rinses (coloring) 5
GLYCINE SOJA (SOYBEAN) OIL 07A - Blushers (all types) 12
GLYCINE SOJA (SOYBEAN) OIL 07B - Face Powders 21
GLYCINE SOJA (SOYBEAN) OIL 07C - Foundations 22
GLYCINE SOJA (SOYBEAN) OIL 07E - Lipstick 103
GLYCINE SOJA (SOYBEAN) OIL 07F - Makeup Bases 3
GLYCINE SOJA (SOYBEAN) OIL 07G - Rouges 14
GLYCINE SOJA (SOYBEAN) OIL 07H - Makeup Fixatives 1
GLYCINE SOJA (SOYBEAN) OIL 07I - Other Makeup Preparations 19
GLYCINE SOJA (SOYBEAN) OIL 08B - Cuticle Softeners 2
GLYCINE SOJA (SOYBEAN) OIL 08E - Nail Polish and Enamel 2
GLYCINE SOJA (SOYBEAN) OIL 08G - Other Manicuring Preparations 2
GLYCINE SOJA (SOYBEAN) OIL 10A - Bath Soaps and Detergents 23
GLYCINE SOJA (SOYBEAN) OIL 10E - Other Personal Cleanliness Products 47
GLYCINE SOJA (SOYBEAN) OIL 11A - Aftershave Lotion 1
GLYCINE SOJA (SOYBEAN) OIL 11D - Preshave Lotions (all types) 1
GLYCINE SOJA (SOYBEAN) OIL 11E - Shaving Cream 2
GLYCINE SOJA (SOYBEAN) OIL 11G - Other Shaving Preparation Products 2
GLYCINE SOJA (SOYBEAN) OIL 12A - Cleansing 36
GLYCINE SOJA (SOYBEAN) OIL 12B - Depilatories 4
GLYCINE SOJA (SOYBEAN) OIL 12C - Face and Neck (exc shave) 50
GLYCINE SOJA (SOYBEAN) OIL 12D - Body and Hand (exc shave) 82
GLYCINE SOJA (SOYBEAN) OIL 12E - Foot Powders and Sprays 1
GLYCINE SOJA (SOYBEAN) OIL 12F - Moisturizing 152
GLYCINE SOJA (SOYBEAN) OIL 12G - Night 19
GLYCINE SOJA (SOYBEAN) OIL 12H - Paste Masks (mud packs) 7
GLYCINE SOJA (SOYBEAN) OIL 12I - Skin Fresheners 9
GLYCINE SOJA (SOYBEAN) OIL 12J - Other Skin Care Preps 49
GLYCINE SOJA (SOYBEAN) OIL 13A - Suntan Gels, Creams, and Liquids 7
CIR Panel Book Page 68
2010 FDA VCRP Raw Data
GLYCINE SOJA (SOYBEAN) OIL 13B - Indoor Tanning Preparations 19
GLYCINE SOJA (SOYBEAN) OIL 13C - Other Suntan Preparations 2
EPOXIDIZED SOYBEAN OIL 08A - Basecoats and Undercoats 1
EPOXIDIZED SOYBEAN OIL 08E - Nail Polish and Enamel 3
EPOXIDIZED SOYBEAN OIL 08G - Other Manicuring Preparations 1
GLYCINE SOJA (SOYBEAN) OIL UNSAPONIFIABLES 07C - Foundations 1
GLYCINE SOJA (SOYBEAN) OIL UNSAPONIFIABLES 12C - Face and Neck (exc shave) 7
GLYCINE SOJA (SOYBEAN) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 1
GLYCINE SOJA (SOYBEAN) OIL UNSAPONIFIABLES 12J - Other Skin Care Preps 3
HYDROGENATED SOYBEAN OIL 03B - Eyeliner 1
HYDROGENATED SOYBEAN OIL 03C - Eye Shadow 1
HYDROGENATED SOYBEAN OIL 03D - Eye Lotion 1
HYDROGENATED SOYBEAN OIL 03G - Other Eye Makeup Preparations 1
HYDROGENATED SOYBEAN OIL 05F - Shampoos (non-coloring) 1
HYDROGENATED SOYBEAN OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
HYDROGENATED SOYBEAN OIL 07D - Leg and Body Paints 1
HYDROGENATED SOYBEAN OIL 07E - Lipstick 3
HYDROGENATED SOYBEAN OIL 07I - Other Makeup Preparations 3
HYDROGENATED SOYBEAN OIL 12A - Cleansing 2
HYDROGENATED SOYBEAN OIL 12C - Face and Neck (exc shave) 4
HYDROGENATED SOYBEAN OIL 12D - Body and Hand (exc shave) 7
HYDROGENATED SOYBEAN OIL 12F - Moisturizing 8
HYDROGENATED SOYBEAN OIL 12J - Other Skin Care Preps 2
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 01A - Baby Shampoos 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 16
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 01C - Other Baby Products 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 02A - Bath Oils, Tablets, and Salts 3
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 02B - Bubble Baths 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 02C - Bath Capsules 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 02D - Other Bath Preparations 6
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03B - Eyeliner 12
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03C - Eye Shadow 17
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03D - Eye Lotion 21
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03F - Mascara 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03G - Other Eye Makeup Preparations 13
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 04E - Other Fragrance Preparation 12
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05A - Hair Conditioner 68
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05B - Hair Spray (aerosol fixatives) 4
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05C - Hair Straighteners 3
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05F - Shampoos (non-coloring) 30
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 25
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05H - Wave Sets 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05I - Other Hair Preparations 48
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 81
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 06G - Hair Bleaches 3
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 06H - Other Hair Coloring Preparation 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07A - Blushers (all types) 23
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07B - Face Powders 7
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07C - Foundations 19
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07E - Lipstick 260
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07H - Makeup Fixatives 2
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07I - Other Makeup Preparations 19
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 08A - Basecoats and Undercoats 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 08B - Cuticle Softeners 2
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 08C - Nail Creams and Lotions 2
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 08G - Other Manicuring Preparations 3
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 10A - Bath Soaps and Detergents 46
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 10B - Deodorants (underarm) 1
CIR Panel Book Page 69
2010 FDA VCRP Raw Data
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 10E - Other Personal Cleanliness Products 52
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 11A - Aftershave Lotion 2
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 11E - Shaving Cream 7
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 11G - Other Shaving Preparation Products 2
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12A - Cleansing 34
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12B - Depilatories 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12C - Face and Neck (exc shave) 93
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12D - Body and Hand (exc shave) 100
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12E - Foot Powders and Sprays 3
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12F - Moisturizing 225
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12G - Night 25
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12H - Paste Masks (mud packs) 19
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12I - Skin Fresheners 2
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12J - Other Skin Care Preps 76
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 13A - Suntan Gels, Creams, and Liquids 4
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 13B - Indoor Tanning Preparations 9
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 13C - Other Suntan Preparations 6
HYBRID SUNFLOWER SEED OIL 07E - Lipstick 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES03B - Eyeliner 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES12C - Face and Neck (exc shave) 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES12G - Night 1
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES13A - Suntan Gels, Creams, and Liquids 2
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES13B - Indoor Tanning Preparations 1
SUNFLOWER OIL, UNSAPONIFIABLE FRACTION 03G - Other Eye Makeup Preparations 1
SUNFLOWER OIL, UNSAPONIFIABLE FRACTION 12D - Body and Hand (exc shave) 1
SUNFLOWER OIL, UNSAPONIFIABLE FRACTION 12I - Skin Fresheners 1
SUNFLOWER OIL, UNSAPONIFIABLE FRACTION 13A - Suntan Gels, Creams, and Liquids 1
OLEA EUROPAEA (OLIVE) FRUIT OIL 01B - Baby Lotions, Oils, Powders, and Creams 7
OLEA EUROPAEA (OLIVE) FRUIT OIL 01C - Other Baby Products 2
OLEA EUROPAEA (OLIVE) FRUIT OIL 02A - Bath Oils, Tablets, and Salts 7
OLEA EUROPAEA (OLIVE) FRUIT OIL 02D - Other Bath Preparations 7
OLEA EUROPAEA (OLIVE) FRUIT OIL 03B - Eyeliner 1
OLEA EUROPAEA (OLIVE) FRUIT OIL 03C - Eye Shadow 3
OLEA EUROPAEA (OLIVE) FRUIT OIL 03D - Eye Lotion 6
OLEA EUROPAEA (OLIVE) FRUIT OIL 03F - Mascara 9
OLEA EUROPAEA (OLIVE) FRUIT OIL 03G - Other Eye Makeup Preparations 7
OLEA EUROPAEA (OLIVE) FRUIT OIL 04A - Cologne and Toilet waters 2
OLEA EUROPAEA (OLIVE) FRUIT OIL 04E - Other Fragrance Preparation 4
OLEA EUROPAEA (OLIVE) FRUIT OIL 05A - Hair Conditioner 54
OLEA EUROPAEA (OLIVE) FRUIT OIL 05C - Hair Straighteners 8
OLEA EUROPAEA (OLIVE) FRUIT OIL 05F - Shampoos (non-coloring) 39
OLEA EUROPAEA (OLIVE) FRUIT OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 55
OLEA EUROPAEA (OLIVE) FRUIT OIL 05I - Other Hair Preparations 34
OLEA EUROPAEA (OLIVE) FRUIT OIL 07A - Blushers (all types) 9
OLEA EUROPAEA (OLIVE) FRUIT OIL 07B - Face Powders 6
OLEA EUROPAEA (OLIVE) FRUIT OIL 07C - Foundations 3
OLEA EUROPAEA (OLIVE) FRUIT OIL 07E - Lipstick 26
OLEA EUROPAEA (OLIVE) FRUIT OIL 07F - Makeup Bases 3
OLEA EUROPAEA (OLIVE) FRUIT OIL 07I - Other Makeup Preparations 10
OLEA EUROPAEA (OLIVE) FRUIT OIL 08B - Cuticle Softeners 2
OLEA EUROPAEA (OLIVE) FRUIT OIL 08C - Nail Creams and Lotions 1
OLEA EUROPAEA (OLIVE) FRUIT OIL 08E - Nail Polish and Enamel 1
OLEA EUROPAEA (OLIVE) FRUIT OIL 08G - Other Manicuring Preparations 1
OLEA EUROPAEA (OLIVE) FRUIT OIL 10A - Bath Soaps and Detergents 95
OLEA EUROPAEA (OLIVE) FRUIT OIL 10B - Deodorants (underarm) 3
OLEA EUROPAEA (OLIVE) FRUIT OIL 10E - Other Personal Cleanliness Products 26
OLEA EUROPAEA (OLIVE) FRUIT OIL 11A - Aftershave Lotion 1
OLEA EUROPAEA (OLIVE) FRUIT OIL 11B - Beard Softeners 1
OLEA EUROPAEA (OLIVE) FRUIT OIL 11E - Shaving Cream 12
OLEA EUROPAEA (OLIVE) FRUIT OIL 11F - Shaving Soap 2
CIR Panel Book Page 70
2010 FDA VCRP Raw Data
OLEA EUROPAEA (OLIVE) FRUIT OIL 11G - Other Shaving Preparation Products 2
OLEA EUROPAEA (OLIVE) FRUIT OIL 12A - Cleansing 40
OLEA EUROPAEA (OLIVE) FRUIT OIL 12C - Face and Neck (exc shave) 58
OLEA EUROPAEA (OLIVE) FRUIT OIL 12D - Body and Hand (exc shave) 111
OLEA EUROPAEA (OLIVE) FRUIT OIL 12F - Moisturizing 183
OLEA EUROPAEA (OLIVE) FRUIT OIL 12G - Night 9
OLEA EUROPAEA (OLIVE) FRUIT OIL 12H - Paste Masks (mud packs) 6
OLEA EUROPAEA (OLIVE) FRUIT OIL 12J - Other Skin Care Preps 35
OLEA EUROPAEA (OLIVE) FRUIT OIL 13A - Suntan Gels, Creams, and Liquids 3
OLEA EUROPAEA (OLIVE) FRUIT OIL 13B - Indoor Tanning Preparations 18
OLEA EUROPAEA (OLIVE) FRUIT OIL 13C - Other Suntan Preparations 3
HYDROGENATED OLIVE OIL 03B - Eyeliner 1
HYDROGENATED OLIVE OIL 03C - Eye Shadow 1
HYDROGENATED OLIVE OIL 03D - Eye Lotion 1
HYDROGENATED OLIVE OIL 03F - Mascara 5
HYDROGENATED OLIVE OIL 03G - Other Eye Makeup Preparations 5
HYDROGENATED OLIVE OIL 05A - Hair Conditioner 4
HYDROGENATED OLIVE OIL 05F - Shampoos (non-coloring) 6
HYDROGENATED OLIVE OIL 05I - Other Hair Preparations 1
HYDROGENATED OLIVE OIL 07E - Lipstick 7
HYDROGENATED OLIVE OIL 10A - Bath Soaps and Detergents 1
HYDROGENATED OLIVE OIL 11F - Shaving Soap 1
HYDROGENATED OLIVE OIL 12A - Cleansing 1
HYDROGENATED OLIVE OIL 12C - Face and Neck (exc shave) 3
HYDROGENATED OLIVE OIL 12D - Body and Hand (exc shave) 2
HYDROGENATED OLIVE OIL 12F - Moisturizing 4
HYDROGENATED OLIVE OIL 12G - Night 2
HYDROGENATED OLIVE OIL 12I - Skin Fresheners 3
HYDROGENATED OLIVE OIL 12J - Other Skin Care Preps 2
HYDROGENATED OLIVE OIL UNSAPONIFIABLES 07C - Foundations 1
HYDROGENATED OLIVE OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 1
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 03D - Eye Lotion 2
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 03F - Mascara 4
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 03G - Other Eye Makeup Preparations 6
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 05A - Hair Conditioner 2
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 05C - Hair Straighteners 1
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 05F - Shampoos (non-coloring) 2
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 05I - Other Hair Preparations 1
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 07B - Face Powders 1
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 07E - Lipstick 1
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 07I - Other Makeup Preparations 2
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 10A - Bath Soaps and Detergents 4
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12C - Face and Neck (exc shave) 14
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 2
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12F - Moisturizing 26
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12G - Night 4
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12J - Other Skin Care Preps 3
OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 13C - Other Suntan Preparations 2
OLIVE OIL FATTY ACIDS, POTASSIUM SALTS 10E - Other Personal Cleanliness Products 1
OLIVE OIL FATTY ACIDS, POTASSIUM SALTS 11E - Shaving Cream 2
SODIUM OLIVATE 01C - Other Baby Products 1
SODIUM OLIVATE 10A - Bath Soaps and Detergents 9
SODIUM OLIVATE 11E - Shaving Cream 2
SODIUM OLIVATE 12J - Other Skin Care Preps 4
CIR Panel Book Page 71
2010 FDA VCRP Raw Data
ACTINIDIA CHINENSIS (KIWI) SEED OIL 04E - Other Fragrance Preparation 1
ACTINIDIA CHINENSIS (KIWI) SEED OIL 05A - Hair Conditioner 2
ACTINIDIA CHINENSIS (KIWI) SEED OIL 07E - Lipstick 1
ACTINIDIA CHINENSIS (KIWI) SEED OIL 12G - Night 3
ADANSONIA DIGITATA SEED OIL 01A - Baby Shampoos 1
ADANSONIA DIGITATA SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 1
ADANSONIA DIGITATA SEED OIL 12F - Moisturizing 2
ADANSONIA DIGITATA SEED OIL 12H - Paste Masks (mud packs) 1
ADANSONIA DIGITATA SEED OIL 12J - Other Skin Care Preps 1
ARGANIA SPINOSA KERNEL OIL 02D - Other Bath Preparations 1
ARGANIA SPINOSA KERNEL OIL 03A - Eyebrow Pencil 1
ARGANIA SPINOSA KERNEL OIL 03B - Eyeliner 3
ARGANIA SPINOSA KERNEL OIL 03C - Eye Shadow 2
ARGANIA SPINOSA KERNEL OIL 03D - Eye Lotion 1
ARGANIA SPINOSA KERNEL OIL 03F - Mascara 2
ARGANIA SPINOSA KERNEL OIL 05A - Hair Conditioner 2
ARGANIA SPINOSA KERNEL OIL 05F - Shampoos (non-coloring) 1
ARGANIA SPINOSA KERNEL OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 2
ARGANIA SPINOSA KERNEL OIL 05I - Other Hair Preparations 3
ARGANIA SPINOSA KERNEL OIL 07A - Blushers (all types) 1
ARGANIA SPINOSA KERNEL OIL 07B - Face Powders 1
ARGANIA SPINOSA KERNEL OIL 07E - Lipstick 9
ARGANIA SPINOSA KERNEL OIL 07I - Other Makeup Preparations 1
ARGANIA SPINOSA KERNEL OIL 08E - Nail Polish and Enamel 1
ARGANIA SPINOSA KERNEL OIL 08G - Other Manicuring Preparations 1
ARGANIA SPINOSA KERNEL OIL 10A - Bath Soaps and Detergents 2
ARGANIA SPINOSA KERNEL OIL 10E - Other Personal Cleanliness Products 1
ARGANIA SPINOSA KERNEL OIL 11A - Aftershave Lotion 1
ARGANIA SPINOSA KERNEL OIL 11E - Shaving Cream 1
ARGANIA SPINOSA KERNEL OIL 11G - Other Shaving Preparation Products 1
ARGANIA SPINOSA KERNEL OIL 12A - Cleansing 2
ARGANIA SPINOSA KERNEL OIL 12C - Face and Neck (exc shave) 8
ARGANIA SPINOSA KERNEL OIL 12D - Body and Hand (exc shave) 12
ARGANIA SPINOSA KERNEL OIL 12F - Moisturizing 12
ARGANIA SPINOSA KERNEL OIL 12G - Night 3
ARGANIA SPINOSA KERNEL OIL 12H - Paste Masks (mud packs) 2
ARGANIA SPINOSA KERNEL OIL 12J - Other Skin Care Preps 3
ARGANIA SPINOSA KERNEL OIL 13A - Suntan Gels, Creams, and Liquids 3
ARGANIA SPINOSA KERNEL OIL 13B - Indoor Tanning Preparations 11
ARGANIA SPINOSA KERNEL OIL 13C - Other Suntan Preparations 6
ASTROCARYUM MURUMURU SEED BUTTER 03B - Eyeliner 3
ASTROCARYUM MURUMURU SEED BUTTER 03D - Eye Lotion 7
ASTROCARYUM MURUMURU SEED BUTTER 03G - Other Eye Makeup Preparations 11
ASTROCARYUM MURUMURU SEED BUTTER 05A - Hair Conditioner 4
ASTROCARYUM MURUMURU SEED BUTTER 05E - Rinses (non-coloring) 1
ASTROCARYUM MURUMURU SEED BUTTER 05F - Shampoos (non-coloring) 3
ASTROCARYUM MURUMURU SEED BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
ASTROCARYUM MURUMURU SEED BUTTER 05I - Other Hair Preparations 2
ASTROCARYUM MURUMURU SEED BUTTER 06H - Other Hair Coloring Preparation 3
ASTROCARYUM MURUMURU SEED BUTTER 07B - Face Powders 5
ASTROCARYUM MURUMURU SEED BUTTER 07C - Foundations 23
ASTROCARYUM MURUMURU SEED BUTTER 07E - Lipstick 22
ASTROCARYUM MURUMURU SEED BUTTER 07I - Other Makeup Preparations 6
ASTROCARYUM MURUMURU SEED BUTTER 10A - Bath Soaps and Detergents 1
ASTROCARYUM MURUMURU SEED BUTTER 10E - Other Personal Cleanliness Products 2
ASTROCARYUM MURUMURU SEED BUTTER 11A - Aftershave Lotion 1
ASTROCARYUM MURUMURU SEED BUTTER 12A - Cleansing 4
ASTROCARYUM MURUMURU SEED BUTTER 12C - Face and Neck (exc shave) 5
CIR Panel Book Page 72
2010 FDA VCRP Raw Data
ASTROCARYUM MURUMURU SEED BUTTER 12D - Body and Hand (exc shave) 21
ASTROCARYUM MURUMURU SEED BUTTER 12F - Moisturizing 57
ASTROCARYUM MURUMURU SEED BUTTER 12G - Night 6
ASTROCARYUM MURUMURU SEED BUTTER 12H - Paste Masks (mud packs) 3
ASTROCARYUM MURUMURU SEED BUTTER 12J - Other Skin Care Preps 1
AVENA SATIVA (OAT) KERNEL OIL 01A - Baby Shampoos 2
AVENA SATIVA (OAT) KERNEL OIL 01B - Baby Lotions, Oils, Powders, and Creams 4
AVENA SATIVA (OAT) KERNEL OIL 02B - Bubble Baths 1
AVENA SATIVA (OAT) KERNEL OIL 07I - Other Makeup Preparations 1
AVENA SATIVA (OAT) KERNEL OIL 10A - Bath Soaps and Detergents 1
AVENA SATIVA (OAT) KERNEL OIL 10E - Other Personal Cleanliness Products 1
AVENA SATIVA (OAT) KERNEL OIL 12A - Cleansing 1
AVENA SATIVA (OAT) KERNEL OIL 12D - Body and Hand (exc shave) 3
AVENA SATIVA (OAT) KERNEL OIL 12F - Moisturizing 27
AVENA SATIVA (OAT) KERNEL OIL 12G - Night 1
AVENA SATIVA (OAT) KERNEL OIL 13C - Other Suntan Preparations 1
BORAGO OFFICINALIS SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 3
BORAGO OFFICINALIS SEED OIL 02A - Bath Oils, Tablets, and Salts 1
BORAGO OFFICINALIS SEED OIL 03C - Eye Shadow 2
BORAGO OFFICINALIS SEED OIL 03D - Eye Lotion 3
BORAGO OFFICINALIS SEED OIL 03F - Mascara 2
BORAGO OFFICINALIS SEED OIL 04E - Other Fragrance Preparation 1
BORAGO OFFICINALIS SEED OIL 05A - Hair Conditioner 3
BORAGO OFFICINALIS SEED OIL 05B - Hair Spray (aerosol fixatives) 2
BORAGO OFFICINALIS SEED OIL 05F - Shampoos (non-coloring) 2
BORAGO OFFICINALIS SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 3
BORAGO OFFICINALIS SEED OIL 07A - Blushers (all types) 2
BORAGO OFFICINALIS SEED OIL 07C - Foundations 1
BORAGO OFFICINALIS SEED OIL 07E - Lipstick 1
BORAGO OFFICINALIS SEED OIL 07I - Other Makeup Preparations 1
BORAGO OFFICINALIS SEED OIL 10A - Bath Soaps and Detergents 2
BORAGO OFFICINALIS SEED OIL 10E - Other Personal Cleanliness Products 2
BORAGO OFFICINALIS SEED OIL 12A - Cleansing 7
BORAGO OFFICINALIS SEED OIL 12C - Face and Neck (exc shave) 30
BORAGO OFFICINALIS SEED OIL 12D - Body and Hand (exc shave) 23
BORAGO OFFICINALIS SEED OIL 12F - Moisturizing 54
BORAGO OFFICINALIS SEED OIL 12G - Night 8
BORAGO OFFICINALIS SEED OIL 12H - Paste Masks (mud packs) 3
BORAGO OFFICINALIS SEED OIL 12J - Other Skin Care Preps 17
BORAGO OFFICINALIS SEED OIL 13B - Indoor Tanning Preparations 7
CAMELINA SATIVA SEED OIL 05A - Hair Conditioner 8
CAMELINA SATIVA SEED OIL 05F - Shampoos (non-coloring) 7
CAMELINA SATIVA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
CAMELINA SATIVA SEED OIL 05I - Other Hair Preparations 13
CAMELINA SATIVA SEED OIL 07E - Lipstick 34
CAMELINA SATIVA SEED OIL 12C - Face and Neck (exc shave) 3
CAMELINA SATIVA SEED OIL 12D - Body and Hand (exc shave) 4
CAMELINA SATIVA SEED OIL 12F - Moisturizing 6
CAMELLIA OLEIFERA SEED OIL 05F - Shampoos (non-coloring) 1
CAMELLIA OLEIFERA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
CAMELLIA OLEIFERA SEED OIL 07E - Lipstick 3
CAMELLIA OLEIFERA SEED OIL 12A - Cleansing 1
CAMELLIA OLEIFERA SEED OIL 12C - Face and Neck (exc shave) 2
CAMELLIA OLEIFERA SEED OIL 12D - Body and Hand (exc shave) 7
CAMELLIA OLEIFERA SEED OIL 12F - Moisturizing 8
CAMELLIA OLEIFERA SEED OIL 12G - Night 2
CIR Panel Book Page 73
2010 FDA VCRP Raw Data
HYDROGENATED CAMELLIA OLEIFERA SEED OIL 12F - Moisturizing 1
CAMELLIA SINENSIS SEED OIL 05A - Hair Conditioner 1
CAMELLIA SINENSIS SEED OIL 05F - Shampoos (non-coloring) 1
CAMELLIA SINENSIS SEED OIL 07B - Face Powders 1
CAMELLIA SINENSIS SEED OIL 07E - Lipstick 1
CAMELLIA SINENSIS SEED OIL 07I - Other Makeup Preparations 2
CAMELLIA SINENSIS SEED OIL 10A - Bath Soaps and Detergents 2
CAMELLIA SINENSIS SEED OIL 12F - Moisturizing 4
CARYOCAR BRASILIENSE FRUIT OIL 03D - Eye Lotion 12
CARYOCAR BRASILIENSE FRUIT OIL 05A - Hair Conditioner 1
CARYOCAR BRASILIENSE FRUIT OIL 07E - Lipstick 12
CARYOCAR BRASILIENSE FRUIT OIL 12C - Face and Neck (exc shave) 2
CARYOCAR BRASILIENSE FRUIT OIL 12D - Body and Hand (exc shave) 2
CARYOCAR BRASILIENSE FRUIT OIL 12F - Moisturizing 1
CARYOCAR BRASILIENSE FRUIT OIL 12H - Paste Masks (mud packs) 1
QUINOA OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
CITRULLUS LANATUS (WATERMELON) SEED OIL 07A - Blushers (all types) 1
CITRULLUS VULGARIS (WATERMELON) SEED OIL 07I - Other Makeup Preparations 1
CITRUS PARADISI (GRAPEFRUIT) SEED OIL 10A - Bath Soaps and Detergents 1
CITRUS PARADISI (GRAPEFRUIT) SEED OIL 12C - Face and Neck (exc shave) 1
CITRUS PARADISI (GRAPEFRUIT) SEED OIL 12D - Body and Hand (exc shave) 1
CITRUS PARADISI (GRAPEFRUIT) SEED OIL 12F - Moisturizing 3
CITRUS MEDICA LIMONUM (LEMON) SEED OIL 10A - Bath Soaps and Detergents 1
CITRUS MEDICA LIMONUM (LEMON) SEED OIL 12F - Moisturizing 1
CITRUS MEDICA LIMONUM (LEMON) SEED OIL 12H - Paste Masks (mud packs) 1
CITRUS MEDICA LIMONUM (LEMON) SEED OIL 12J - Other Skin Care Preps 2
CUCUMIS SATIVUS (CUCUMBER) OIL 03D - Eye Lotion 1
CUCUMIS SATIVUS (CUCUMBER) OIL 05F - Shampoos (non-coloring) 1
CUCUMIS SATIVUS (CUCUMBER) OIL 12C - Face and Neck (exc shave) 1
CUCUMIS SATIVUS (CUCUMBER) OIL 12F - Moisturizing 1
CUCUMIS SATIVUS (CUCUMBER) OIL 12J - Other Skin Care Preps 2
CUCURBITA PEPO (PUMPKIN) SEED OIL 03D - Eye Lotion 1
CUCURBITA PEPO (PUMPKIN) SEED OIL 04C - Powders (dusting and talcum, excluding aftershave talc) 1
CUCURBITA PEPO (PUMPKIN) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
CUCURBITA PEPO (PUMPKIN) SEED OIL 12A - Cleansing 1
CUCURBITA PEPO (PUMPKIN) SEED OIL 12C - Face and Neck (exc shave) 4
CUCURBITA PEPO (PUMPKIN) SEED OIL 12D - Body and Hand (exc shave) 3
CUCURBITA PEPO (PUMPKIN) SEED OIL 12F - Moisturizing 5
CUCURBITA PEPO (PUMPKIN) SEED OIL 12G - Night 1
CUCURBITA PEPO (PUMPKIN) SEED OIL 13A - Suntan Gels, Creams, and Liquids 1
EUTERPE OLERACEA FRUIT OIL 03C - Eye Shadow 1
EUTERPE OLERACEA FRUIT OIL 03D - Eye Lotion 1
EUTERPE OLERACEA FRUIT OIL 05A - Hair Conditioner 2
EUTERPE OLERACEA FRUIT OIL 05B - Hair Spray (aerosol fixatives) 1
EUTERPE OLERACEA FRUIT OIL 05F - Shampoos (non-coloring) 4
CIR Panel Book Page 74
2010 FDA VCRP Raw Data
EUTERPE OLERACEA FRUIT OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 5
EUTERPE OLERACEA FRUIT OIL 05I - Other Hair Preparations 3
EUTERPE OLERACEA FRUIT OIL 07E - Lipstick 1
EUTERPE OLERACEA FRUIT OIL 10A - Bath Soaps and Detergents 2
EUTERPE OLERACEA FRUIT OIL 10E - Other Personal Cleanliness Products 1
EUTERPE OLERACEA FRUIT OIL 12A - Cleansing 1
EUTERPE OLERACEA FRUIT OIL 12C - Face and Neck (exc shave) 2
EUTERPE OLERACEA FRUIT OIL 12F - Moisturizing 3
EUTERPE OLERACEA FRUIT OIL 12G - Night 2
IRVINGIA GABONENSIS KERNEL BUTTER 03D - Eye Lotion 2
IRVINGIA GABONENSIS KERNEL BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
IRVINGIA GABONENSIS KERNEL BUTTER 07E - Lipstick 64
IRVINGIA GABONENSIS KERNEL BUTTER 07I - Other Makeup Preparations 1
IRVINGIA GABONENSIS KERNEL BUTTER 12C - Face and Neck (exc shave) 11
IRVINGIA GABONENSIS KERNEL BUTTER 12D - Body and Hand (exc shave) 8
IRVINGIA GABONENSIS KERNEL BUTTER 12F - Moisturizing 15
IRVINGIA GABONENSIS KERNEL BUTTER 12G - Night 1
IRVINGIA GABONENSIS KERNEL BUTTER 12J - Other Skin Care Preps 1
IRVINGIA GABONENSIS KERNEL BUTTER 13A - Suntan Gels, Creams, and Liquids 2
IRVINGIA GABONENSIS KERNEL BUTTER 13B - Indoor Tanning Preparations 3
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 1
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 02A - Bath Oils, Tablets, and Salts 2
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 03B - Eyeliner 13
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 03D - Eye Lotion 4
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 03F - Mascara 12
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 03G - Other Eye Makeup Preparations 1
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 05A - Hair Conditioner 17
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 05F - Shampoos (non-coloring) 7
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 17
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 05I - Other Hair Preparations 6
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 43
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 06D - Hair Shampoos (coloring) 2
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 06H - Other Hair Coloring Preparation 1
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 07C - Foundations 6
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 07E - Lipstick 67
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 07I - Other Makeup Preparations 7
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 10A - Bath Soaps and Detergents 3
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 10E - Other Personal Cleanliness Products 1
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 11E - Shaving Cream 2
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 11G - Other Shaving Preparation Products 1
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12A - Cleansing 9
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12C - Face and Neck (exc shave) 24
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12D - Body and Hand (exc shave) 18
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12E - Foot Powders and Sprays 1
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12F - Moisturizing 28
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12G - Night 9
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12H - Paste Masks (mud packs) 3
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12I - Skin Fresheners 1
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12J - Other Skin Care Preps 9
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 13B - Indoor Tanning Preparations 1
LINUM USITATISSIMUM (LINSEED) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 2
LINUM USITATISSIMUM (LINSEED) SEED OIL 02A - Bath Oils, Tablets, and Salts 1
LINUM USITATISSIMUM (LINSEED) SEED OIL 02D - Other Bath Preparations 1
LINUM USITATISSIMUM (LINSEED) SEED OIL 03D - Eye Lotion 2
LINUM USITATISSIMUM (LINSEED) SEED OIL 03G - Other Eye Makeup Preparations 1
LINUM USITATISSIMUM (LINSEED) SEED OIL 05A - Hair Conditioner 13
LINUM USITATISSIMUM (LINSEED) SEED OIL 05B - Hair Spray (aerosol fixatives) 3
LINUM USITATISSIMUM (LINSEED) SEED OIL 05F - Shampoos (non-coloring) 10
LINUM USITATISSIMUM (LINSEED) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 14
CIR Panel Book Page 75
2010 FDA VCRP Raw Data
LINUM USITATISSIMUM (LINSEED) SEED OIL 05I - Other Hair Preparations 2
LINUM USITATISSIMUM (LINSEED) SEED OIL 07I - Other Makeup Preparations 1
LINUM USITATISSIMUM (LINSEED) SEED OIL 08E - Nail Polish and Enamel 2
LINUM USITATISSIMUM (LINSEED) SEED OIL 10A - Bath Soaps and Detergents 4
LINUM USITATISSIMUM (LINSEED) SEED OIL 10E - Other Personal Cleanliness Products 1
LINUM USITATISSIMUM (LINSEED) SEED OIL 11E - Shaving Cream 2
LINUM USITATISSIMUM (LINSEED) SEED OIL 12A - Cleansing 18
LINUM USITATISSIMUM (LINSEED) SEED OIL 12C - Face and Neck (exc shave) 7
LINUM USITATISSIMUM (LINSEED) SEED OIL 12D - Body and Hand (exc shave) 5
LINUM USITATISSIMUM (LINSEED) SEED OIL 12F - Moisturizing 8
LINUM USITATISSIMUM (LINSEED) SEED OIL 12G - Night 2
LINUM USITATISSIMUM (LINSEED) SEED OIL 12I - Skin Fresheners 1
LINUM USITATISSIMUM (LINSEED) SEED OIL 12J - Other Skin Care Preps 2
LINSEED ACID 01B - Baby Lotions, Oils, Powders, and Creams 1
LINSEED ACID 12D - Body and Hand (exc shave) 1
LINSEED ACID 12J - Other Skin Care Preps 1
MANGIFERA INDICA (MANGO) SEED OIL 03B - Eyeliner 13
MANGIFERA INDICA (MANGO) SEED OIL 04E - Other Fragrance Preparation 1
MANGIFERA INDICA (MANGO) SEED OIL 05A - Hair Conditioner 2
MANGIFERA INDICA (MANGO) SEED OIL 05F - Shampoos (non-coloring) 3
MANGIFERA INDICA (MANGO) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
MANGIFERA INDICA (MANGO) SEED OIL 05I - Other Hair Preparations 6
MANGIFERA INDICA (MANGO) SEED OIL 07E - Lipstick 7
MANGIFERA INDICA (MANGO) SEED OIL 07I - Other Makeup Preparations 7
MANGIFERA INDICA (MANGO) SEED OIL 10E - Other Personal Cleanliness Products 2
MANGIFERA INDICA (MANGO) SEED OIL 12C - Face and Neck (exc shave) 8
MANGIFERA INDICA (MANGO) SEED OIL 12D - Body and Hand (exc shave) 7
MANGIFERA INDICA (MANGO) SEED OIL 12F - Moisturizing 9
MANGIFERA INDICA (MANGO) SEED OIL 12G - Night 1
MANGIFERA INDICA (MANGO) SEED OIL 12H - Paste Masks (mud packs) 1
MANGIFERA INDICA (MANGO) SEED OIL 12J - Other Skin Care Preps 4
MANGIFERA INDICA (MANGO) SEED BUTTER 01B - Baby Lotions, Oils, Powders, and Creams 3
MANGIFERA INDICA (MANGO) SEED BUTTER 02B - Bubble Baths 1
MANGIFERA INDICA (MANGO) SEED BUTTER 02D - Other Bath Preparations 3
MANGIFERA INDICA (MANGO) SEED BUTTER 03C - Eye Shadow 4
MANGIFERA INDICA (MANGO) SEED BUTTER 03D - Eye Lotion 2
MANGIFERA INDICA (MANGO) SEED BUTTER 04B - Perfumes 2
MANGIFERA INDICA (MANGO) SEED BUTTER 05A - Hair Conditioner 2
MANGIFERA INDICA (MANGO) SEED BUTTER 05F - Shampoos (non-coloring) 3
MANGIFERA INDICA (MANGO) SEED BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 4
MANGIFERA INDICA (MANGO) SEED BUTTER 05I - Other Hair Preparations 3
MANGIFERA INDICA (MANGO) SEED BUTTER 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 13
MANGIFERA INDICA (MANGO) SEED BUTTER 06H - Other Hair Coloring Preparation 3
MANGIFERA INDICA (MANGO) SEED BUTTER 07A - Blushers (all types) 3
MANGIFERA INDICA (MANGO) SEED BUTTER 07B - Face Powders 5
MANGIFERA INDICA (MANGO) SEED BUTTER 07C - Foundations 1
MANGIFERA INDICA (MANGO) SEED BUTTER 07E - Lipstick 25
MANGIFERA INDICA (MANGO) SEED BUTTER 07H - Makeup Fixatives 3
MANGIFERA INDICA (MANGO) SEED BUTTER 07I - Other Makeup Preparations 7
MANGIFERA INDICA (MANGO) SEED BUTTER 10A - Bath Soaps and Detergents 5
MANGIFERA INDICA (MANGO) SEED BUTTER 10E - Other Personal Cleanliness Products 5
MANGIFERA INDICA (MANGO) SEED BUTTER 12A - Cleansing 3
MANGIFERA INDICA (MANGO) SEED BUTTER 12C - Face and Neck (exc shave) 4
MANGIFERA INDICA (MANGO) SEED BUTTER 12D - Body and Hand (exc shave) 15
MANGIFERA INDICA (MANGO) SEED BUTTER 12F - Moisturizing 39
MANGIFERA INDICA (MANGO) SEED BUTTER 12G - Night 2
MANGIFERA INDICA (MANGO) SEED BUTTER 12H - Paste Masks (mud packs) 3
MANGIFERA INDICA (MANGO) SEED BUTTER 12J - Other Skin Care Preps 10
MANGIFERA INDICA (MANGO) SEED BUTTER 13B - Indoor Tanning Preparations 2
CIR Panel Book Page 76
2010 FDA VCRP Raw Data
SODIUM MANGOSEEDATE 10A - Bath Soaps and Detergents 1
#REF! 03F - Mascara 4
MORINGA PTERYGOSPERMA SEED OIL 07E - Lipstick 1
MORINGA PTERYGOSPERMA SEED OIL 07I - Other Makeup Preparations 1
MORINGA PTERYGOSPERMA SEED OIL 12A - Cleansing 2
MORINGA PTERYGOSPERMA SEED OIL 12C - Face and Neck (exc shave) 2
MORINGA PTERYGOSPERMA SEED OIL 12D - Body and Hand (exc shave) 2
MORINGA PTERYGOSPERMA SEED OIL 12F - Moisturizing 2
MORINGA PTERYGOSPERMA SEED OIL 12J - Other Skin Care Preps 1
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 01B - Baby Lotions, Oils, Powders, and Creams 3
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 02A - Bath Oils, Tablets, and Salts 1
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 02B - Bubble Baths 1
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 03D - Eye Lotion 4
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05A - Hair Conditioner 16
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05B - Hair Spray (aerosol fixatives) 2
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05F - Shampoos (non-coloring) 5
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 6
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05I - Other Hair Preparations 8
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 07A - Blushers (all types) 1
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 07C - Foundations 2
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 07E - Lipstick 14
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 07I - Other Makeup Preparations 2
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 08B - Cuticle Softeners 1
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 08E - Nail Polish and Enamel 2
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 08G - Other Manicuring Preparations 1
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 10A - Bath Soaps and Detergents 4
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 11E - Shaving Cream 1
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12A - Cleansing 6
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12C - Face and Neck (exc shave) 10
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12D - Body and Hand (exc shave) 15
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12F - Moisturizing 24
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12G - Night 8
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12H - Paste Masks (mud packs) 3
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12J - Other Skin Care Preps 9
OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 13B - Indoor Tanning Preparations 1
HYDROGENATED EVENING PRIMROSE OIL 03B - Eyeliner 1
HYDROGENATED EVENING PRIMROSE OIL 12C - Face and Neck (exc shave) 2
HYDROGENATED EVENING PRIMROSE OIL 12D - Body and Hand (exc shave) 5
HYDROGENATED EVENING PRIMROSE OIL 12F - Moisturizing 6
ORBIGNYA COHUNE SEED OIL 05A - Hair Conditioner 1
ORBIGNYA OLEIFERA SEED OIL 02D - Other Bath Preparations 2
ORBIGNYA OLEIFERA SEED OIL 03C - Eye Shadow 1
ORBIGNYA OLEIFERA SEED OIL 03D - Eye Lotion 1
ORBIGNYA OLEIFERA SEED OIL 03G - Other Eye Makeup Preparations 5
ORBIGNYA OLEIFERA SEED OIL 05A - Hair Conditioner 16
ORBIGNYA OLEIFERA SEED OIL 05B - Hair Spray (aerosol fixatives) 5
ORBIGNYA OLEIFERA SEED OIL 05F - Shampoos (non-coloring) 7
ORBIGNYA OLEIFERA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 10
ORBIGNYA OLEIFERA SEED OIL 05I - Other Hair Preparations 5
ORBIGNYA OLEIFERA SEED OIL 06C - Hair Rinses (coloring) 5
ORBIGNYA OLEIFERA SEED OIL 06H - Other Hair Coloring Preparation 3
ORBIGNYA OLEIFERA SEED OIL 07E - Lipstick 57
ORBIGNYA OLEIFERA SEED OIL 07I - Other Makeup Preparations 4
CIR Panel Book Page 77
2010 FDA VCRP Raw Data
ORBIGNYA OLEIFERA SEED OIL 10A - Bath Soaps and Detergents 3
ORBIGNYA OLEIFERA SEED OIL 10E - Other Personal Cleanliness Products 2
ORBIGNYA OLEIFERA SEED OIL 11G - Other Shaving Preparation Products 1
ORBIGNYA OLEIFERA SEED OIL 12A - Cleansing 4
ORBIGNYA OLEIFERA SEED OIL 12C - Face and Neck (exc shave) 3
ORBIGNYA OLEIFERA SEED OIL 12D - Body and Hand (exc shave) 9
ORBIGNYA OLEIFERA SEED OIL 12F - Moisturizing 12
ORBIGNYA OLEIFERA SEED OIL 12G - Night 3
ORBIGNYA OLEIFERA SEED OIL 12J - Other Skin Care Preps 3
PERILLA OCYMOIDES SEED OIL 03D - Eye Lotion 2
PERILLA OCYMOIDES SEED OIL 05A - Hair Conditioner 2
PERILLA OCYMOIDES SEED OIL 07I - Other Makeup Preparations 1
PERILLA OCYMOIDES SEED OIL 12D - Body and Hand (exc shave) 2
HYDROGENATED AVOCADO OIL 05A - Hair Conditioner 1
HYDROGENATED AVOCADO OIL 05F - Shampoos (non-coloring) 1
HYDROGENATED AVOCADO OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
HYDROGENATED AVOCADO OIL 07E - Lipstick 2
HYDROGENATED AVOCADO OIL 12F - Moisturizing 6
PERSEA GRATISSIMA (AVOCADO) BUTTER 07E - Lipstick 11
PERSEA GRATISSIMA (AVOCADO) BUTTER 12F - Moisturizing 4
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 01B - Baby Lotions, Oils, Powders, and Creams 1
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 02D - Other Bath Preparations 4
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 03B - Eyeliner 1
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 03C - Eye Shadow 4
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 03D - Eye Lotion 2
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 03G - Other Eye Makeup Preparations 2
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 04E - Other Fragrance Preparation 4
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 05G - Tonics, Dressings, and Other Hair Grooming Aids 2
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 07E - Lipstick 2
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 07I - Other Makeup Preparations 2
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 08C - Nail Creams and Lotions 2
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 08G - Other Manicuring Preparations 1
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12A - Cleansing 2
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12C - Face and Neck (exc shave) 4
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 6
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12F - Moisturizing 16
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12G - Night 2
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12J - Other Skin Care Preps 5
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 13C - Other Suntan Preparations 1
SODIUM AVOCADOATE 10A - Bath Soaps and Detergents 1
PLUKENETIA VOLUBILIS SEED OIL 03G - Other Eye Makeup Preparations 1
PLUKENETIA VOLUBILIS SEED OIL 07E - Lipstick 3
PLUKENETIA VOLUBILIS SEED OIL 12C - Face and Neck (exc shave) 4
PLUKENETIA VOLUBILIS SEED OIL 12F - Moisturizing 2
PLUKENETIA VOLUBILIS SEED OIL 12G - Night 2
PLUKENETIA VOLUBILIS SEED OIL 12H - Paste Masks (mud packs) 1
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 01B - Baby Lotions, Oils, Powders, and Creams 5
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 01C - Other Baby Products 2
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 02A - Bath Oils, Tablets, and Salts 5
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 02D - Other Bath Preparations 3
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03A - Eyebrow Pencil 1
CIR Panel Book Page 78
2010 FDA VCRP Raw Data
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03B - Eyeliner 1
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03D - Eye Lotion 8
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03E - Eye Makeup Remover 2
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03F - Mascara 4
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03G - Other Eye Makeup Preparations 9
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 04E - Other Fragrance Preparation 5
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05A - Hair Conditioner 33
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05E - Rinses (non-coloring) 1
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05F - Shampoos (non-coloring) 22
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 3
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05I - Other Hair Preparations 19
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 5
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 06D - Hair Shampoos (coloring) 3
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 06G - Hair Bleaches 2
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 07B - Face Powders 1
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 07C - Foundations 4
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 07E - Lipstick 38
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 07I - Other Makeup Preparations 10
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08A - Basecoats and Undercoats 1
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08B - Cuticle Softeners 4
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08C - Nail Creams and Lotions 2
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08E - Nail Polish and Enamel 1
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08G - Other Manicuring Preparations 2
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 10A - Bath Soaps and Detergents 11
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 10B - Deodorants (underarm) 1
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 10E - Other Personal Cleanliness Products 12
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 11A - Aftershave Lotion 2
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 11E - Shaving Cream 1
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 11G - Other Shaving Preparation Products 3
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12A - Cleansing 31
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12B - Depilatories 2
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12C - Face and Neck (exc shave) 47
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12D - Body and Hand (exc shave) 87
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12F - Moisturizing 124
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12G - Night 13
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12H - Paste Masks (mud packs) 3
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12I - Skin Fresheners 4
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12J - Other Skin Care Preps 46
PRUNUS ARMENIACA (APRICOT) KERNEL OIL 13B - Indoor Tanning Preparations 5
HYDROGENATED APRICOT KERNEL OIL 12D - Body and Hand (exc shave) 1
HYDROGENATED APRICOT KERNEL OIL 12F - Moisturizing 1
PRUNUS AVIUM (SWEET CHERRY) SEED OIL 10A - Bath Soaps and Detergents 2
PRUNUS PERSICA (PEACH) KERNEL OIL 02A - Bath Oils, Tablets, and Salts 1
PRUNUS PERSICA (PEACH) KERNEL OIL 05F - Shampoos (non-coloring) 2
PRUNUS PERSICA (PEACH) KERNEL OIL 05I - Other Hair Preparations 2
PRUNUS PERSICA (PEACH) KERNEL OIL 07I - Other Makeup Preparations 1
PRUNUS PERSICA (PEACH) KERNEL OIL 10E - Other Personal Cleanliness Products 1
PRUNUS PERSICA (PEACH) KERNEL OIL 12A - Cleansing 2
PRUNUS PERSICA (PEACH) KERNEL OIL 12C - Face and Neck (exc shave) 1
PRUNUS PERSICA (PEACH) KERNEL OIL 12D - Body and Hand (exc shave) 4
PRUNUS PERSICA (PEACH) KERNEL OIL 12F - Moisturizing 2
PRUNUS PERSICA (PEACH) KERNEL OIL 12J - Other Skin Care Preps 6
PYRUS MALUS (APPLE ) SEED OIL 07E - Lipstick 7
PYRUS MALUS (APPLE ) SEED OIL 12F - Moisturizing 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 03G - Other Eye Makeup Preparations 2
CIR Panel Book Page 79
2010 FDA VCRP Raw Data
RIBES NIGRUM (BLACK CURRANT) SEED OIL 05A - Hair Conditioner 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 05F - Shampoos (non-coloring) 2
RIBES NIGRUM (BLACK CURRANT) SEED OIL 05I - Other Hair Preparations 2
RIBES NIGRUM (BLACK CURRANT) SEED OIL 07C - Foundations 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 07E - Lipstick 7
RIBES NIGRUM (BLACK CURRANT) SEED OIL 07I - Other Makeup Preparations 2
RIBES NIGRUM (BLACK CURRANT) SEED OIL 08A - Basecoats and Undercoats 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 08B - Cuticle Softeners 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 08E - Nail Polish and Enamel 2
RIBES NIGRUM (BLACK CURRANT) SEED OIL 08G - Other Manicuring Preparations 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 10A - Bath Soaps and Detergents 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 10E - Other Personal Cleanliness Products 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 12A - Cleansing 2
RIBES NIGRUM (BLACK CURRANT) SEED OIL 12C - Face and Neck (exc shave) 7
RIBES NIGRUM (BLACK CURRANT) SEED OIL 12D - Body and Hand (exc shave) 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 12F - Moisturizing 14
RIBES NIGRUM (BLACK CURRANT) SEED OIL 12G - Night 2
RIBES NIGRUM (BLACK CURRANT) SEED OIL 12H - Paste Masks (mud packs) 1
RIBES NIGRUM (BLACK CURRANT) SEED OIL 12J - Other Skin Care Preps 2
RUBUS IDAEUS (RASPBERRY) SEED OIL 02D - Other Bath Preparations 1
RUBUS IDAEUS (RASPBERRY) SEED OIL 07E - Lipstick 1
RUBUS IDAEUS (RASPBERRY) SEED OIL 07I - Other Makeup Preparations 2
RUBUS IDAEUS (RASPBERRY) SEED OIL 12A - Cleansing 1
RUBUS IDAEUS (RASPBERRY) SEED OIL 12C - Face and Neck (exc shave) 2
RUBUS IDAEUS (RASPBERRY) SEED OIL 12F - Moisturizing 1
RUBUS IDAEUS (RASPBERRY) SEED OIL 12G - Night 2
SCLEROCARYA BIRREA SEED OIL 04E - Other Fragrance Preparation 2
SCLEROCARYA BIRREA SEED OIL 05A - Hair Conditioner 2
SCLEROCARYA BIRREA SEED OIL 05F - Shampoos (non-coloring) 1
SCLEROCARYA BIRREA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 3
SCLEROCARYA BIRREA SEED OIL 07E - Lipstick 6
SCLEROCARYA BIRREA SEED OIL 10E - Other Personal Cleanliness Products 2
SCLEROCARYA BIRREA SEED OIL 12A - Cleansing 1
SCLEROCARYA BIRREA SEED OIL 12C - Face and Neck (exc shave) 1
SCLEROCARYA BIRREA SEED OIL 12D - Body and Hand (exc shave) 3
SCLEROCARYA BIRREA SEED OIL 12F - Moisturizing 5
SCLEROCARYA BIRREA SEED OIL 12G - Night 2
SCLEROCARYA BIRREA SEED OIL 12J - Other Skin Care Preps 1
SOLANUM LYCOPERSICUM (TOMATO) SEED OIL 12C - Face and Neck (exc shave) 1
THEOBROMA CACAO (COCOA) SEED BUTTER 01B - Baby Lotions, Oils, Powders, and Creams 8
THEOBROMA CACAO (COCOA) SEED BUTTER 01C - Other Baby Products 4
THEOBROMA CACAO (COCOA) SEED BUTTER 02D - Other Bath Preparations 2
THEOBROMA CACAO (COCOA) SEED BUTTER 03A - Eyebrow Pencil 1
THEOBROMA CACAO (COCOA) SEED BUTTER 03B - Eyeliner 3
THEOBROMA CACAO (COCOA) SEED BUTTER 03D - Eye Lotion 5
THEOBROMA CACAO (COCOA) SEED BUTTER 03E - Eye Makeup Remover 1
THEOBROMA CACAO (COCOA) SEED BUTTER 03G - Other Eye Makeup Preparations 1
THEOBROMA CACAO (COCOA) SEED BUTTER 05A - Hair Conditioner 10
THEOBROMA CACAO (COCOA) SEED BUTTER 05C - Hair Straighteners 7
THEOBROMA CACAO (COCOA) SEED BUTTER 05F - Shampoos (non-coloring) 2
THEOBROMA CACAO (COCOA) SEED BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 2
THEOBROMA CACAO (COCOA) SEED BUTTER 05I - Other Hair Preparations 3
THEOBROMA CACAO (COCOA) SEED BUTTER 07A - Blushers (all types) 2
THEOBROMA CACAO (COCOA) SEED BUTTER 07E - Lipstick 33
THEOBROMA CACAO (COCOA) SEED BUTTER 07F - Makeup Bases 5
THEOBROMA CACAO (COCOA) SEED BUTTER 07G - Rouges 1
THEOBROMA CACAO (COCOA) SEED BUTTER 07I - Other Makeup Preparations 10
CIR Panel Book Page 80
2010 FDA VCRP Raw Data
THEOBROMA CACAO (COCOA) SEED BUTTER 08B - Cuticle Softeners 1
THEOBROMA CACAO (COCOA) SEED BUTTER 10A - Bath Soaps and Detergents 26
THEOBROMA CACAO (COCOA) SEED BUTTER 10E - Other Personal Cleanliness Products 9
THEOBROMA CACAO (COCOA) SEED BUTTER 11A - Aftershave Lotion 1
THEOBROMA CACAO (COCOA) SEED BUTTER 11B - Beard Softeners 1
THEOBROMA CACAO (COCOA) SEED BUTTER 11E - Shaving Cream 2
THEOBROMA CACAO (COCOA) SEED BUTTER 11G - Other Shaving Preparation Products 5
THEOBROMA CACAO (COCOA) SEED BUTTER 12A - Cleansing 4
THEOBROMA CACAO (COCOA) SEED BUTTER 12B - Depilatories 2
THEOBROMA CACAO (COCOA) SEED BUTTER 12C - Face and Neck (exc shave) 13
THEOBROMA CACAO (COCOA) SEED BUTTER 12D - Body and Hand (exc shave) 72
THEOBROMA CACAO (COCOA) SEED BUTTER 12E - Foot Powders and Sprays 2
THEOBROMA CACAO (COCOA) SEED BUTTER 12F - Moisturizing 147
THEOBROMA CACAO (COCOA) SEED BUTTER 12G - Night 7
THEOBROMA CACAO (COCOA) SEED BUTTER 12H - Paste Masks (mud packs) 5
THEOBROMA CACAO (COCOA) SEED BUTTER 12I - Skin Fresheners 4
THEOBROMA CACAO (COCOA) SEED BUTTER 12J - Other Skin Care Preps 26
THEOBROMA CACAO (COCOA) SEED BUTTER 13A - Suntan Gels, Creams, and Liquids 7
THEOBROMA CACAO (COCOA) SEED BUTTER 13B - Indoor Tanning Preparations 8
THEOBROMA GRANDIFLORUM SEED BUTTER 02B - Bubble Baths 4
THEOBROMA GRANDIFLORUM SEED BUTTER 02D - Other Bath Preparations 1
THEOBROMA GRANDIFLORUM SEED BUTTER 03A - Eyebrow Pencil 1
THEOBROMA GRANDIFLORUM SEED BUTTER 03B - Eyeliner 13
THEOBROMA GRANDIFLORUM SEED BUTTER 03D - Eye Lotion 1
THEOBROMA GRANDIFLORUM SEED BUTTER 03G - Other Eye Makeup Preparations 6
THEOBROMA GRANDIFLORUM SEED BUTTER 05A - Hair Conditioner 3
THEOBROMA GRANDIFLORUM SEED BUTTER 05F - Shampoos (non-coloring) 2
THEOBROMA GRANDIFLORUM SEED BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 2
THEOBROMA GRANDIFLORUM SEED BUTTER 05I - Other Hair Preparations 2
THEOBROMA GRANDIFLORUM SEED BUTTER 06H - Other Hair Coloring Preparation 3
THEOBROMA GRANDIFLORUM SEED BUTTER 07E - Lipstick 49
THEOBROMA GRANDIFLORUM SEED BUTTER 07I - Other Makeup Preparations 4
THEOBROMA GRANDIFLORUM SEED BUTTER 10A - Bath Soaps and Detergents 7
THEOBROMA GRANDIFLORUM SEED BUTTER 10E - Other Personal Cleanliness Products 12
THEOBROMA GRANDIFLORUM SEED BUTTER 11E - Shaving Cream 1
THEOBROMA GRANDIFLORUM SEED BUTTER 12A - Cleansing 1
THEOBROMA GRANDIFLORUM SEED BUTTER 12C - Face and Neck (exc shave) 6
THEOBROMA GRANDIFLORUM SEED BUTTER 12D - Body and Hand (exc shave) 6
THEOBROMA GRANDIFLORUM SEED BUTTER 12F - Moisturizing 25
THEOBROMA GRANDIFLORUM SEED BUTTER 12G - Night 1
THEOBROMA GRANDIFLORUM SEED BUTTER 12J - Other Skin Care Preps 2
THEOBROMA GRANDIFLORUM SEED BUTTER 13C - Other Suntan Preparations 1
TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES03D - Eye Lotion 1
TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES12C - Face and Neck (exc shave) 11
TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES12D - Body and Hand (exc shave) 1
TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES12F - Moisturizing 2
TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES12G - Night 1
TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES13C - Other Suntan Preparations 1
WHEAT GERM ACID 05A - Hair Conditioner 13
WHEAT GERM ACID 05G - Tonics, Dressings, and Other Hair Grooming Aids 2
WHEAT GERM ACID 05I - Other Hair Preparations 1
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 03D - Eye Lotion 2
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 05A - Hair Conditioner 1
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 05I - Other Hair Preparations 3
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 10E - Other Personal Cleanliness Products 1
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12C - Face and Neck (exc shave) 2
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12D - Body and Hand (exc shave) 2
CIR Panel Book Page 81
2010 FDA VCRP Raw Data
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12F - Moisturizing 3
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12G - Night 3
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12H - Paste Masks (mud packs) 1
VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12J - Other Skin Care Preps 3
VACCINIUM OXYCOCCOS (CRANBERRY) SEED OIL 12F - Moisturizing 1
VACCINIUM OXYCOCCOS SEED OIL 12A - Cleansing 1
VACCINIUM OXYCOCCOS SEED OIL 12D - Body and Hand (exc shave) 1
VACCINIUM OXYCOCCOS SEED OIL 12F - Moisturizing 1
VITIS VINIFERA (GRAPE) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 4
VITIS VINIFERA (GRAPE) SEED OIL 01C - Other Baby Products 1
VITIS VINIFERA (GRAPE) SEED OIL 02A - Bath Oils, Tablets, and Salts 4
VITIS VINIFERA (GRAPE) SEED OIL 02D - Other Bath Preparations 3
VITIS VINIFERA (GRAPE) SEED OIL 03C - Eye Shadow 1
VITIS VINIFERA (GRAPE) SEED OIL 03D - Eye Lotion 4
VITIS VINIFERA (GRAPE) SEED OIL 03G - Other Eye Makeup Preparations 3
VITIS VINIFERA (GRAPE) SEED OIL 04E - Other Fragrance Preparation 6
VITIS VINIFERA (GRAPE) SEED OIL 05A - Hair Conditioner 17
VITIS VINIFERA (GRAPE) SEED OIL 05F - Shampoos (non-coloring) 6
VITIS VINIFERA (GRAPE) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 9
VITIS VINIFERA (GRAPE) SEED OIL 05I - Other Hair Preparations 14
VITIS VINIFERA (GRAPE) SEED OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 4
VITIS VINIFERA (GRAPE) SEED OIL 06D - Hair Shampoos (coloring) 1
VITIS VINIFERA (GRAPE) SEED OIL 06G - Hair Bleaches 2
VITIS VINIFERA (GRAPE) SEED OIL 06H - Other Hair Coloring Preparation 3
VITIS VINIFERA (GRAPE) SEED OIL 07A - Blushers (all types) 1
VITIS VINIFERA (GRAPE) SEED OIL 07B - Face Powders 2
VITIS VINIFERA (GRAPE) SEED OIL 07E - Lipstick 34
VITIS VINIFERA (GRAPE) SEED OIL 07I - Other Makeup Preparations 6
VITIS VINIFERA (GRAPE) SEED OIL 08B - Cuticle Softeners 2
VITIS VINIFERA (GRAPE) SEED OIL 08C - Nail Creams and Lotions 3
VITIS VINIFERA (GRAPE) SEED OIL 08E - Nail Polish and Enamel 1
VITIS VINIFERA (GRAPE) SEED OIL 08G - Other Manicuring Preparations 2
VITIS VINIFERA (GRAPE) SEED OIL 10A - Bath Soaps and Detergents 15
VITIS VINIFERA (GRAPE) SEED OIL 10E - Other Personal Cleanliness Products 19
VITIS VINIFERA (GRAPE) SEED OIL 11A - Aftershave Lotion 1
VITIS VINIFERA (GRAPE) SEED OIL 11D - Preshave Lotions (all types) 1
VITIS VINIFERA (GRAPE) SEED OIL 11E - Shaving Cream 3
VITIS VINIFERA (GRAPE) SEED OIL 11G - Other Shaving Preparation Products 2
VITIS VINIFERA (GRAPE) SEED OIL 12A - Cleansing 11
VITIS VINIFERA (GRAPE) SEED OIL 12C - Face and Neck (exc shave) 18
VITIS VINIFERA (GRAPE) SEED OIL 12D - Body and Hand (exc shave) 59
VITIS VINIFERA (GRAPE) SEED OIL 12F - Moisturizing 134
VITIS VINIFERA (GRAPE) SEED OIL 12G - Night 15
VITIS VINIFERA (GRAPE) SEED OIL 12H - Paste Masks (mud packs) 6
VITIS VINIFERA (GRAPE) SEED OIL 12I - Skin Fresheners 5
VITIS VINIFERA (GRAPE) SEED OIL 12J - Other Skin Care Preps 27
VITIS VINIFERA (GRAPE) SEED OIL 13A - Suntan Gels, Creams, and Liquids 1
VITIS VINIFERA (GRAPE) SEED OIL 13B - Indoor Tanning Preparations 15
SODIUM GRAPESEEDATE 12J - Other Skin Care Preps 4
HYDROGENATED GRAPESEED OIL 05A - Hair Conditioner 1
HYDROGENATED GRAPESEED OIL 07E - Lipstick 1
HYDROGENATED GRAPESEED OIL 07I - Other Makeup Preparations 1
HYDROGENATED GRAPESEED OIL 08B - Cuticle Softeners 1
HYDROGENATED GRAPESEED OIL 10A - Bath Soaps and Detergents 1
HYDROGENATED GRAPESEED OIL 12A - Cleansing 1
HYDROGENATED GRAPESEED OIL 13A - Suntan Gels, Creams, and Liquids 1
CIR Panel Book Page 82
2010 FDA VCRP Raw Data
BASSIA LATIFOLIA SEED BUTTER 03C - Eye Shadow 4
BASSIA LATIFOLIA SEED BUTTER 07A - Blushers (all types) 1
BASSIA LATIFOLIA SEED BUTTER 07B - Face Powders 5
BASSIA LATIFOLIA SEED BUTTER 10A - Bath Soaps and Detergents 1
BASSIA LATIFOLIA SEED BUTTER 10E - Other Personal Cleanliness Products 4
BASSIA LATIFOLIA SEED BUTTER 12F - Moisturizing 7
CAMELLIA KISSI SEED OIL 02A - Bath Oils, Tablets, and Salts 1
CAMELLIA KISSI SEED OIL 03C - Eye Shadow 4
CAMELLIA KISSI SEED OIL 05A - Hair Conditioner 3
CAMELLIA KISSI SEED OIL 05E - Rinses (non-coloring) 1
CAMELLIA KISSI SEED OIL 05F - Shampoos (non-coloring) 2
CAMELLIA KISSI SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 2
CAMELLIA KISSI SEED OIL 05I - Other Hair Preparations 3
CAMELLIA KISSI SEED OIL 07A - Blushers (all types) 2
CAMELLIA KISSI SEED OIL 07B - Face Powders 1
CAMELLIA KISSI SEED OIL 07E - Lipstick 1
CAMELLIA KISSI SEED OIL 10A - Bath Soaps and Detergents 1
CAMELLIA KISSI SEED OIL 12A - Cleansing 4
CAMELLIA KISSI SEED OIL 12C - Face and Neck (exc shave) 3
CAMELLIA KISSI SEED OIL 12D - Body and Hand (exc shave) 7
CAMELLIA KISSI SEED OIL 12F - Moisturizing 7
CAMELLIA KISSI SEED OIL 12G - Night 2
CAMELLIA KISSI SEED OIL 12H - Paste Masks (mud packs) 1
CAMELLIA KISSI SEED OIL 12J - Other Skin Care Preps 2
CRAMBE ABYSSINICA SEED OIL 03G - Other Eye Makeup Preparations 1
CRAMBE ABYSSINICA SEED OIL 05A - Hair Conditioner 5
CRAMBE ABYSSINICA SEED OIL 05C - Hair Straighteners 1
CRAMBE ABYSSINICA SEED OIL 05F - Shampoos (non-coloring) 1
CRAMBE ABYSSINICA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 5
CRAMBE ABYSSINICA SEED OIL 05I - Other Hair Preparations 2
CRAMBE ABYSSINICA SEED OIL 06H - Other Hair Coloring Preparation 4
CRAMBE ABYSSINICA SEED OIL 07E - Lipstick 1
CRAMBE ABYSSINICA SEED OIL 12C - Face and Neck (exc shave) 2
CRAMBE ABYSSINICA SEED OIL 12D - Body and Hand (exc shave) 1
CRAMBE ABYSSINICA SEED OIL 12G - Night 3
GARCINIA INDICA SEED BUTTER 03D - Eye Lotion 1
GARCINIA INDICA SEED BUTTER 07E - Lipstick 3
GARCINIA INDICA SEED BUTTER 07I - Other Makeup Preparations 5
GARCINIA INDICA SEED BUTTER 10A - Bath Soaps and Detergents 1
GARCINIA INDICA SEED BUTTER 11F - Shaving Soap 2
GARCINIA INDICA SEED BUTTER 12C - Face and Neck (exc shave) 2
GARCINIA INDICA SEED BUTTER 12D - Body and Hand (exc shave) 2
GARCINIA INDICA SEED BUTTER 12F - Moisturizing 9
GARCINIA INDICA SEED BUTTER 12J - Other Skin Care Preps 5
HIPPOPHAE RHAMNOIDES FRUIT OIL 03D - Eye Lotion 1
HIPPOPHAE RHAMNOIDES FRUIT OIL 08G - Other Manicuring Preparations 1
HIPPOPHAE RHAMNOIDES FRUIT OIL 12C - Face and Neck (exc shave) 3
HIPPOPHAE RHAMNOIDES FRUIT OIL 12F - Moisturizing 2
HIPPOPHAE RHAMNOIDES OIL 05A - Hair Conditioner 3
HIPPOPHAE RHAMNOIDES OIL 05F - Shampoos (non-coloring) 1
HIPPOPHAE RHAMNOIDES OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 2
HIPPOPHAE RHAMNOIDES OIL 08A - Basecoats and Undercoats 1
HIPPOPHAE RHAMNOIDES OIL 08B - Cuticle Softeners 1
HIPPOPHAE RHAMNOIDES OIL 08E - Nail Polish and Enamel 3
CIR Panel Book Page 83
2010 FDA VCRP Raw Data
HIPPOPHAE RHAMNOIDES OIL 08G - Other Manicuring Preparations 3
HIPPOPHAE RHAMNOIDES OIL 10E - Other Personal Cleanliness Products 1
LUFFA CYLINDRICA SEED OIL 03C - Eye Shadow 1
LUFFA CYLINDRICA SEED OIL 07A - Blushers (all types) 3
LUFFA CYLINDRICA SEED OIL 07B - Face Powders 1
LUFFA CYLINDRICA SEED OIL 07E - Lipstick 9
LUFFA CYLINDRICA SEED OIL 12C - Face and Neck (exc shave) 2
LUFFA CYLINDRICA SEED OIL 12F - Moisturizing 1
LUFFA CYLINDRICA SEED OIL 12G - Night 1
LUFFA CYLINDRICA SEED OIL 13B - Indoor Tanning Preparations 1
LUFFA CYLINDRICA SEED OIL 13C - Other Suntan Preparations 2
LUPINUS ALBUS SEED OIL 13C - Other Suntan Preparations 1
LYCIUM BARBARUM SEED OIL 03G - Other Eye Makeup Preparations 1
LYCIUM BARBARUM SEED OIL 07E - Lipstick 1
ORBIGNYA SPECIOSA KERNEL OIL 05A - Hair Conditioner 2
ORBIGNYA SPECIOSA KERNEL OIL 05F - Shampoos (non-coloring) 2
ORBIGNYA SPECIOSA KERNEL OIL 05I - Other Hair Preparations 1
ORBIGNYA SPECIOSA KERNEL OIL 06H - Other Hair Coloring Preparation 3
PASSIFLORA EDULIS SEED OIL 03C - Eye Shadow 1
PASSIFLORA EDULIS SEED OIL 03D - Eye Lotion 2
PASSIFLORA EDULIS SEED OIL 05A - Hair Conditioner 2
PASSIFLORA EDULIS SEED OIL 05B - Hair Spray (aerosol fixatives) 3
PASSIFLORA EDULIS SEED OIL 05F - Shampoos (non-coloring) 1
PASSIFLORA EDULIS SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
PASSIFLORA EDULIS SEED OIL 05I - Other Hair Preparations 3
PASSIFLORA EDULIS SEED OIL 06H - Other Hair Coloring Preparation 3
PASSIFLORA EDULIS SEED OIL 07B - Face Powders 2
PASSIFLORA EDULIS SEED OIL 07E - Lipstick 14
PASSIFLORA EDULIS SEED OIL 10E - Other Personal Cleanliness Products 1
PASSIFLORA EDULIS SEED OIL 12A - Cleansing 2
PASSIFLORA EDULIS SEED OIL 12C - Face and Neck (exc shave) 6
PASSIFLORA EDULIS SEED OIL 12D - Body and Hand (exc shave) 2
PASSIFLORA EDULIS SEED OIL 12F - Moisturizing 16
PASSIFLORA EDULIS SEED OIL 12G - Night 1
PASSIFLORA EDULIS SEED OIL 12J - Other Skin Care Preps 2
PUNICA GRANATUM SEED OIL 03D - Eye Lotion 2
PUNICA GRANATUM SEED OIL 07A - Blushers (all types) 1
PUNICA GRANATUM SEED OIL 07E - Lipstick 30
PUNICA GRANATUM SEED OIL 10A - Bath Soaps and Detergents 2
PUNICA GRANATUM SEED OIL 12C - Face and Neck (exc shave) 3
PUNICA GRANATUM SEED OIL 12F - Moisturizing 5
PUNICA GRANATUM SEED OIL 12G - Night 1
PUNICA GRANATUM SEED OIL 12J - Other Skin Care Preps 2
ROSA CANINA FRUIT OIL 02B - Bubble Baths 1
ROSA CANINA FRUIT OIL 03B - Eyeliner 4
ROSA CANINA FRUIT OIL 03D - Eye Lotion 7
ROSA CANINA FRUIT OIL 03F - Mascara 2
ROSA CANINA FRUIT OIL 03G - Other Eye Makeup Preparations 4
ROSA CANINA FRUIT OIL 04E - Other Fragrance Preparation 1
ROSA CANINA FRUIT OIL 05A - Hair Conditioner 4
ROSA CANINA FRUIT OIL 05F - Shampoos (non-coloring) 2
CIR Panel Book Page 84
2010 FDA VCRP Raw Data
ROSA CANINA FRUIT OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
ROSA CANINA FRUIT OIL 05I - Other Hair Preparations 2
ROSA CANINA FRUIT OIL 07C - Foundations 3
ROSA CANINA FRUIT OIL 07E - Lipstick 7
ROSA CANINA FRUIT OIL 07I - Other Makeup Preparations 2
ROSA CANINA FRUIT OIL 08G - Other Manicuring Preparations 1
ROSA CANINA FRUIT OIL 10A - Bath Soaps and Detergents 3
ROSA CANINA FRUIT OIL 12A - Cleansing 4
ROSA CANINA FRUIT OIL 12C - Face and Neck (exc shave) 23
ROSA CANINA FRUIT OIL 12D - Body and Hand (exc shave) 7
ROSA CANINA FRUIT OIL 12F - Moisturizing 22
ROSA CANINA FRUIT OIL 12G - Night 9
ROSA CANINA FRUIT OIL 12H - Paste Masks (mud packs) 1
ROSA CANINA FRUIT OIL 12I - Skin Fresheners 7
ROSA CANINA FRUIT OIL 12J - Other Skin Care Preps 3
ROSA CANINA FRUIT OIL 13B - Indoor Tanning Preparations 1
RUBUS CHAMAEMORUS SEED OIL 12C - Face and Neck (exc shave) 2
RUBUS CHAMAEMORUS SEED OIL 12G - Night 1
VACCINIUM MYRTILLUS SEED OIL 07E - Lipstick 29
VACCINIUM MYRTILLUS SEED OIL 12A - Cleansing 1
VACCINIUM MYRTILLUS SEED OIL 12D - Body and Hand (exc shave) 1
VACCINIUM MYRTILLUS SEED OIL 12F - Moisturizing 2
VACCINIUM VITIS-IDAEA SEED OIL 08A - Basecoats and Undercoats 1
VACCINIUM VITIS-IDAEA SEED OIL 08B - Cuticle Softeners 1
VACCINIUM VITIS-IDAEA SEED OIL 08E - Nail Polish and Enamel 3
VACCINIUM VITIS-IDAEA SEED OIL 08G - Other Manicuring Preparations 3
VACCINIUM VITIS-IDAEA SEED OIL 12D - Body and Hand (exc shave) 1
VANILLA PLANIFOLIA FRUIT OIL 03D - Eye Lotion 1
VANILLA PLANIFOLIA FRUIT OIL 03G - Other Eye Makeup Preparations 1
VANILLA PLANIFOLIA FRUIT OIL 07I - Other Makeup Preparations 2
VANILLA PLANIFOLIA FRUIT OIL 10E - Other Personal Cleanliness Products 1
VANILLA PLANIFOLIA FRUIT OIL 12F - Moisturizing 4
CIR Panel Book Page 85
2010 FDA VCRP Raw Data
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 5
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 01C - Other Baby Products 1
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 02A - Bath Oils, Tablets, and Salts 2
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 02D - Other Bath Preparations 1
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 03B - Eyeliner 6
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 03C - Eye Shadow 4
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 03D - Eye Lotion 2
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 03G - Other Eye Makeup Preparations 3
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 04E - Other Fragrance Preparation 5
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05A - Hair Conditioner 26
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05C - Hair Straighteners 1
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05F - Shampoos (non-coloring) 10
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 37
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05I - Other Hair Preparations 5
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 06H - Other Hair Coloring Preparation 2
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07A - Blushers (all types) 11
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07B - Face Powders 3
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07C - Foundations 3
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07E - Lipstick 83
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07F - Makeup Bases 1
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07I - Other Makeup Preparations 7
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08A - Basecoats and Undercoats 1
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08B - Cuticle Softeners 4
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08C - Nail Creams and Lotions 2
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08E - Nail Polish and Enamel 16
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08G - Other Manicuring Preparations 9
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 10A - Bath Soaps and Detergents 19
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 10E - Other Personal Cleanliness Products 12
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 11A - Aftershave Lotion 1
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 11D - Preshave Lotions (all types) 1
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 11E - Shaving Cream 1
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12A - Cleansing 22
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12B - Depilatories 4
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12C - Face and Neck (exc shave) 15
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12D - Body and Hand (exc shave) 62
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12F - Moisturizing 70
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12G - Night 5
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12H - Paste Masks (mud packs) 5
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12I - Skin Fresheners 3
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12J - Other Skin Care Preps 33
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 13B - Indoor Tanning Preparations 4
CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 13C - Other Suntan Preparations 1
HYBRID SAFFLOWER OIL 05A - Hair Conditioner 2
HYBRID SAFFLOWER OIL 12A - Cleansing 1
HYBRID SAFFLOWER OIL 12C - Face and Neck (exc shave) 1
HYBRID SAFFLOWER OIL 12D - Body and Hand (exc shave) 2
HYBRID SAFFLOWER OIL 12F - Moisturizing 4
HYBRID SAFFLOWER OIL 12G - Night 1
HYBRID SAFFLOWER OIL 12H - Paste Masks (mud packs) 1
HYBRID SAFFLOWER OIL 12J - Other Skin Care Preps 1
HYBRID SAFFLOWER OIL 13A - Suntan Gels, Creams, and Liquids 1
ELAEIS GUINEENSIS (PALM) OIL 01B - Baby Lotions, Oils, Powders, and Creams 1
ELAEIS GUINEENSIS (PALM) OIL 01C - Other Baby Products 1
ELAEIS GUINEENSIS (PALM) OIL 03A - Eyebrow Pencil 5
ELAEIS GUINEENSIS (PALM) OIL 03B - Eyeliner 1
ELAEIS GUINEENSIS (PALM) OIL 03D - Eye Lotion 3
ELAEIS GUINEENSIS (PALM) OIL 03G - Other Eye Makeup Preparations 3
ELAEIS GUINEENSIS (PALM) OIL 05A - Hair Conditioner 16
ELAEIS GUINEENSIS (PALM) OIL 05B - Hair Spray (aerosol fixatives) 3
ELAEIS GUINEENSIS (PALM) OIL 05F - Shampoos (non-coloring) 3
ELAEIS GUINEENSIS (PALM) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 4
CIR Panel Book Page 86
2010 FDA VCRP Raw Data
ELAEIS GUINEENSIS (PALM) OIL 05I - Other Hair Preparations 17
ELAEIS GUINEENSIS (PALM) OIL 07E - Lipstick 11
ELAEIS GUINEENSIS (PALM) OIL 07H - Makeup Fixatives 3
ELAEIS GUINEENSIS (PALM) OIL 07I - Other Makeup Preparations 8
ELAEIS GUINEENSIS (PALM) OIL 10A - Bath Soaps and Detergents 59
ELAEIS GUINEENSIS (PALM) OIL 10E - Other Personal Cleanliness Products 9
ELAEIS GUINEENSIS (PALM) OIL 11A - Aftershave Lotion 7
ELAEIS GUINEENSIS (PALM) OIL 11E - Shaving Cream 4
ELAEIS GUINEENSIS (PALM) OIL 12A - Cleansing 8
ELAEIS GUINEENSIS (PALM) OIL 12C - Face and Neck (exc shave) 17
ELAEIS GUINEENSIS (PALM) OIL 12D - Body and Hand (exc shave) 34
ELAEIS GUINEENSIS (PALM) OIL 12F - Moisturizing 28
ELAEIS GUINEENSIS (PALM) OIL 12G - Night 6
ELAEIS GUINEENSIS (PALM) OIL 12H - Paste Masks (mud packs) 2
ELAEIS GUINEENSIS (PALM) OIL 12J - Other Skin Care Preps 13
ELAEIS GUINEENSIS (PALM) OIL 13B - Indoor Tanning Preparations 5
ELAEIS GUINEENSIS (PALM) OIL 13C - Other Suntan Preparations 1
ELAEIS GUINEENSIS (PALM) KERNEL OIL 02B - Bubble Baths 1
ELAEIS GUINEENSIS (PALM) KERNEL OIL 03A - Eyebrow Pencil 5
ELAEIS GUINEENSIS (PALM) KERNEL OIL 03B - Eyeliner 1
ELAEIS GUINEENSIS (PALM) KERNEL OIL 03D - Eye Lotion 2
ELAEIS GUINEENSIS (PALM) KERNEL OIL 03G - Other Eye Makeup Preparations 2
ELAEIS GUINEENSIS (PALM) KERNEL OIL 05A - Hair Conditioner 5
ELAEIS GUINEENSIS (PALM) KERNEL OIL 05F - Shampoos (non-coloring) 1
ELAEIS GUINEENSIS (PALM) KERNEL OIL 07E - Lipstick 6
ELAEIS GUINEENSIS (PALM) KERNEL OIL 07H - Makeup Fixatives 3
ELAEIS GUINEENSIS (PALM) KERNEL OIL 07I - Other Makeup Preparations 8
ELAEIS GUINEENSIS (PALM) KERNEL OIL 10A - Bath Soaps and Detergents 9
ELAEIS GUINEENSIS (PALM) KERNEL OIL 12A - Cleansing 1
ELAEIS GUINEENSIS (PALM) KERNEL OIL 12C - Face and Neck (exc shave) 7
ELAEIS GUINEENSIS (PALM) KERNEL OIL 12D - Body and Hand (exc shave) 9
ELAEIS GUINEENSIS (PALM) KERNEL OIL 12F - Moisturizing 12
ELAEIS GUINEENSIS (PALM) KERNEL OIL 12G - Night 2
ELAEIS GUINEENSIS (PALM) KERNEL OIL 12J - Other Skin Care Preps 1
ELAEIS GUINEENSIS (PALM) KERNEL OIL 13B - Indoor Tanning Preparations 2
HYDROGENATED PALM OIL 03A - Eyebrow Pencil 13
HYDROGENATED PALM OIL 03B - Eyeliner 9
HYDROGENATED PALM OIL 03D - Eye Lotion 2
HYDROGENATED PALM OIL 03F - Mascara 29
HYDROGENATED PALM OIL 03G - Other Eye Makeup Preparations 8
HYDROGENATED PALM OIL 07C - Foundations 1
HYDROGENATED PALM OIL 07E - Lipstick 12
HYDROGENATED PALM OIL 07H - Makeup Fixatives 3
HYDROGENATED PALM OIL 07I - Other Makeup Preparations 13
HYDROGENATED PALM OIL 10A - Bath Soaps and Detergents 15
HYDROGENATED PALM OIL 10E - Other Personal Cleanliness Products 2
HYDROGENATED PALM OIL 11F - Shaving Soap 1
HYDROGENATED PALM OIL 12C - Face and Neck (exc shave) 9
HYDROGENATED PALM OIL 12D - Body and Hand (exc shave) 9
HYDROGENATED PALM OIL 12F - Moisturizing 17
HYDROGENATED PALM OIL 12G - Night 4
HYDROGENATED PALM OIL 12J - Other Skin Care Preps 2
HYDROGENATED PALM OIL 13A - Suntan Gels, Creams, and Liquids 1
HYDROGENATED PALM OIL 13B - Indoor Tanning Preparations 2
HYDROGENATED PALM KERNEL OIL 03A - Eyebrow Pencil 1
HYDROGENATED PALM KERNEL OIL 03G - Other Eye Makeup Preparations 1
HYDROGENATED PALM KERNEL OIL 04E - Other Fragrance Preparation 1
HYDROGENATED PALM KERNEL OIL 07E - Lipstick 5
HYDROGENATED PALM KERNEL OIL 10A - Bath Soaps and Detergents 2
CIR Panel Book Page 87
2010 FDA VCRP Raw Data
HYDROGENATED PALM KERNEL OIL 12C - Face and Neck (exc shave) 6
HYDROGENATED PALM KERNEL OIL 12D - Body and Hand (exc shave) 10
HYDROGENATED PALM KERNEL OIL 12F - Moisturizing 13
HYDROGENATED PALM KERNEL OIL 12G - Night 1
HYDROGENATED PALM KERNEL OIL 12J - Other Skin Care Preps 5
HYDROGENATED PALM KERNEL OIL 13A - Suntan Gels, Creams, and Liquids 2
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 03B - Eyeliner 2
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 03F - Mascara 2
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 04B - Perfumes 1
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 04E - Other Fragrance Preparation 10
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 05I - Other Hair Preparations 2
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 07C - Foundations 1
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 07E - Lipstick 9
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 08B - Cuticle Softeners 1
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 10A - Bath Soaps and Detergents 5
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 10B - Deodorants (underarm) 1
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 10E - Other Personal Cleanliness Products 2
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 11E - Shaving Cream 4
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12A - Cleansing 3
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12C - Face and Neck (exc shave) 3
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12D - Body and Hand (exc shave) 14
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12E - Foot Powders and Sprays 1
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12F - Moisturizing 10
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12H - Paste Masks (mud packs) 1
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12J - Other Skin Care Preps 8
GOSSYPIUM HERBACEUM (COTTON) SEED OIL 13B - Indoor Tanning Preparations 3
HYDROGENATED COTTONSEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 8
HYDROGENATED COTTONSEED OIL 03A - Eyebrow Pencil 32
HYDROGENATED COTTONSEED OIL 03B - Eyeliner 87
HYDROGENATED COTTONSEED OIL 03C - Eye Shadow 18
HYDROGENATED COTTONSEED OIL 03D - Eye Lotion 1
HYDROGENATED COTTONSEED OIL 03F - Mascara 2
HYDROGENATED COTTONSEED OIL 03G - Other Eye Makeup Preparations 15
HYDROGENATED COTTONSEED OIL 05A - Hair Conditioner 3
HYDROGENATED COTTONSEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1
HYDROGENATED COTTONSEED OIL 07D - Leg and Body Paints 1
HYDROGENATED COTTONSEED OIL 07E - Lipstick 168
HYDROGENATED COTTONSEED OIL 07I - Other Makeup Preparations 13
HYDROGENATED COTTONSEED OIL 12F - Moisturizing 9
HYDROGENATED COTTONSEED OIL 12H - Paste Masks (mud packs) 1
HYDROGENATED COTTONSEED OIL 12I - Skin Fresheners 1
HYDROGENATED COTTONSEED OIL 12J - Other Skin Care Preps 2
ORYZA SATIVA (RICE) BRAN OIL 01B - Baby Lotions, Oils, Powders, and Creams 1
ORYZA SATIVA (RICE) BRAN OIL 01C - Other Baby Products 1
ORYZA SATIVA (RICE) BRAN OIL 02A - Bath Oils, Tablets, and Salts 6
ORYZA SATIVA (RICE) BRAN OIL 02B - Bubble Baths 1
ORYZA SATIVA (RICE) BRAN OIL 02D - Other Bath Preparations 10
ORYZA SATIVA (RICE) BRAN OIL 03D - Eye Lotion 1
ORYZA SATIVA (RICE) BRAN OIL 03F - Mascara 3
ORYZA SATIVA (RICE) BRAN OIL 03G - Other Eye Makeup Preparations 1
ORYZA SATIVA (RICE) BRAN OIL 04E - Other Fragrance Preparation 6
ORYZA SATIVA (RICE) BRAN OIL 05A - Hair Conditioner 13
ORYZA SATIVA (RICE) BRAN OIL 05B - Hair Spray (aerosol fixatives) 4
ORYZA SATIVA (RICE) BRAN OIL 05E - Rinses (non-coloring) 1
ORYZA SATIVA (RICE) BRAN OIL 05F - Shampoos (non-coloring) 10
ORYZA SATIVA (RICE) BRAN OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 11
ORYZA SATIVA (RICE) BRAN OIL 05I - Other Hair Preparations 3
ORYZA SATIVA (RICE) BRAN OIL 07C - Foundations 1
ORYZA SATIVA (RICE) BRAN OIL 07E - Lipstick 17
CIR Panel Book Page 88
2010 FDA VCRP Raw Data
ORYZA SATIVA (RICE) BRAN OIL 07I - Other Makeup Preparations 2
ORYZA SATIVA (RICE) BRAN OIL 08B - Cuticle Softeners 2
ORYZA SATIVA (RICE) BRAN OIL 08G - Other Manicuring Preparations 3
ORYZA SATIVA (RICE) BRAN OIL 10A - Bath Soaps and Detergents 39
ORYZA SATIVA (RICE) BRAN OIL 10E - Other Personal Cleanliness Products 9
ORYZA SATIVA (RICE) BRAN OIL 11G - Other Shaving Preparation Products 1
ORYZA SATIVA (RICE) BRAN OIL 12A - Cleansing 9
ORYZA SATIVA (RICE) BRAN OIL 12C - Face and Neck (exc shave) 22
ORYZA SATIVA (RICE) BRAN OIL 12D - Body and Hand (exc shave) 50
ORYZA SATIVA (RICE) BRAN OIL 12E - Foot Powders and Sprays 1
ORYZA SATIVA (RICE) BRAN OIL 12F - Moisturizing 88
ORYZA SATIVA (RICE) BRAN OIL 12G - Night 11
ORYZA SATIVA (RICE) BRAN OIL 12H - Paste Masks (mud packs) 5
ORYZA SATIVA (RICE) BRAN OIL 12J - Other Skin Care Preps 34
ORYZA SATIVA (RICE) BRAN OIL 13A - Suntan Gels, Creams, and Liquids 1
ORYZA SATIVA (RICE) BRAN OIL 13B - Indoor Tanning Preparations 1
ORYZA SATIVA (RICE) BRAN OIL 13C - Other Suntan Preparations 3
ORYZA SATIVA (RICE) GERM OIL 02A - Bath Oils, Tablets, and Salts 1
ORYZA SATIVA (RICE) GERM OIL 03F - Mascara 2
ORYZA SATIVA (RICE) GERM OIL 07E - Lipstick 4
ORYZA SATIVA (RICE) GERM OIL 07I - Other Makeup Preparations 1
ORYZA SATIVA (RICE) GERM OIL 10E - Other Personal Cleanliness Products 1
ORYZA SATIVA (RICE) GERM OIL 12A - Cleansing 3
ORYZA SATIVA (RICE) GERM OIL 12C - Face and Neck (exc shave) 11
ORYZA SATIVA (RICE) GERM OIL 12D - Body and Hand (exc shave) 5
ORYZA SATIVA (RICE) GERM OIL 12F - Moisturizing 4
ORYZA SATIVA (RICE) GERM OIL 12J - Other Skin Care Preps 2
SESAMUM INDICUM (SESAME) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 3
SESAMUM INDICUM (SESAME) SEED OIL 02A - Bath Oils, Tablets, and Salts 2
SESAMUM INDICUM (SESAME) SEED OIL 02D - Other Bath Preparations 3
SESAMUM INDICUM (SESAME) SEED OIL 03B - Eyeliner 2
SESAMUM INDICUM (SESAME) SEED OIL 03C - Eye Shadow 2
SESAMUM INDICUM (SESAME) SEED OIL 03D - Eye Lotion 4
SESAMUM INDICUM (SESAME) SEED OIL 03E - Eye Makeup Remover 1
SESAMUM INDICUM (SESAME) SEED OIL 03G - Other Eye Makeup Preparations 5
SESAMUM INDICUM (SESAME) SEED OIL 04C - Powders (dusting and talcum, excluding aftershave talc) 1
SESAMUM INDICUM (SESAME) SEED OIL 04E - Other Fragrance Preparation 1
SESAMUM INDICUM (SESAME) SEED OIL 05A - Hair Conditioner 12
SESAMUM INDICUM (SESAME) SEED OIL 05B - Hair Spray (aerosol fixatives) 3
SESAMUM INDICUM (SESAME) SEED OIL 05F - Shampoos (non-coloring) 16
SESAMUM INDICUM (SESAME) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 10
SESAMUM INDICUM (SESAME) SEED OIL 05H - Wave Sets 1
SESAMUM INDICUM (SESAME) SEED OIL 05I - Other Hair Preparations 17
SESAMUM INDICUM (SESAME) SEED OIL 07C - Foundations 11
SESAMUM INDICUM (SESAME) SEED OIL 07E - Lipstick 52
SESAMUM INDICUM (SESAME) SEED OIL 07F - Makeup Bases 23
SESAMUM INDICUM (SESAME) SEED OIL 07H - Makeup Fixatives 1
SESAMUM INDICUM (SESAME) SEED OIL 07I - Other Makeup Preparations 5
SESAMUM INDICUM (SESAME) SEED OIL 08B - Cuticle Softeners 2
SESAMUM INDICUM (SESAME) SEED OIL 08C - Nail Creams and Lotions 2
SESAMUM INDICUM (SESAME) SEED OIL 08G - Other Manicuring Preparations 3
SESAMUM INDICUM (SESAME) SEED OIL 10A - Bath Soaps and Detergents 20
SESAMUM INDICUM (SESAME) SEED OIL 10E - Other Personal Cleanliness Products 8
SESAMUM INDICUM (SESAME) SEED OIL 11A - Aftershave Lotion 3
SESAMUM INDICUM (SESAME) SEED OIL 11B - Beard Softeners 1
SESAMUM INDICUM (SESAME) SEED OIL 11D - Preshave Lotions (all types) 1
SESAMUM INDICUM (SESAME) SEED OIL 11E - Shaving Cream 4
SESAMUM INDICUM (SESAME) SEED OIL 12A - Cleansing 16
SESAMUM INDICUM (SESAME) SEED OIL 12C - Face and Neck (exc shave) 24
SESAMUM INDICUM (SESAME) SEED OIL 12D - Body and Hand (exc shave) 76
SESAMUM INDICUM (SESAME) SEED OIL 12F - Moisturizing 74
CIR Panel Book Page 89
2010 FDA VCRP Raw Data
SESAMUM INDICUM (SESAME) SEED OIL 12G - Night 14
SESAMUM INDICUM (SESAME) SEED OIL 12H - Paste Masks (mud packs) 5
SESAMUM INDICUM (SESAME) SEED OIL 12J - Other Skin Care Preps 41
SESAMUM INDICUM (SESAME) SEED OIL 13A - Suntan Gels, Creams, and Liquids 6
SESAMUM INDICUM (SESAME) SEED OIL 13B - Indoor Tanning Preparations 3
SESAMUM INDICUM (SESAME) SEED OIL 13C - Other Suntan Preparations 2
SESAMUM INDICUM (SESAME) OIL UNSAPONIFIABLES 07E - Lipstick 11
SESAMUM INDICUM (SESAME) OIL UNSAPONIFIABLES 12C - Face and Neck (exc shave) 4
SESAMUM INDICUM (SESAME) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 1
SESAMUM INDICUM (SESAME) OIL UNSAPONIFIABLES 12F - Moisturizing 1
ZEA MAYS (CORN) OIL 01B - Baby Lotions, Oils, Powders, and Creams 5
ZEA MAYS (CORN) OIL 01C - Other Baby Products 3
ZEA MAYS (CORN) OIL 03C - Eye Shadow 17
ZEA MAYS (CORN) OIL 03D - Eye Lotion 7
ZEA MAYS (CORN) OIL 03E - Eye Makeup Remover 4
ZEA MAYS (CORN) OIL 03F - Mascara 1
ZEA MAYS (CORN) OIL 03G - Other Eye Makeup Preparations 6
ZEA MAYS (CORN) OIL 05A - Hair Conditioner 11
ZEA MAYS (CORN) OIL 05B - Hair Spray (aerosol fixatives) 1
ZEA MAYS (CORN) OIL 05E - Rinses (non-coloring) 1
ZEA MAYS (CORN) OIL 05F - Shampoos (non-coloring) 12
ZEA MAYS (CORN) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 11
ZEA MAYS (CORN) OIL 05I - Other Hair Preparations 4
ZEA MAYS (CORN) OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests)178
ZEA MAYS (CORN) OIL 06B - Hair Tints 1
ZEA MAYS (CORN) OIL 06C - Hair Rinses (coloring) 1
ZEA MAYS (CORN) OIL 06G - Hair Bleaches 1
ZEA MAYS (CORN) OIL 06H - Other Hair Coloring Preparation 2
ZEA MAYS (CORN) OIL 07A - Blushers (all types) 22
ZEA MAYS (CORN) OIL 07B - Face Powders 31
ZEA MAYS (CORN) OIL 07C - Foundations 11
ZEA MAYS (CORN) OIL 07E - Lipstick 30
ZEA MAYS (CORN) OIL 07I - Other Makeup Preparations 7
ZEA MAYS (CORN) OIL 08B - Cuticle Softeners 1
ZEA MAYS (CORN) OIL 08E - Nail Polish and Enamel 1
ZEA MAYS (CORN) OIL 08G - Other Manicuring Preparations 1
ZEA MAYS (CORN) OIL 10A - Bath Soaps and Detergents 2
ZEA MAYS (CORN) OIL 10B - Deodorants (underarm) 4
ZEA MAYS (CORN) OIL 12A - Cleansing 13
ZEA MAYS (CORN) OIL 12C - Face and Neck (exc shave) 53
ZEA MAYS (CORN) OIL 12D - Body and Hand (exc shave) 34
ZEA MAYS (CORN) OIL 12F - Moisturizing 68
ZEA MAYS (CORN) OIL 12G - Night 11
ZEA MAYS (CORN) OIL 12H - Paste Masks (mud packs) 11
ZEA MAYS (CORN) OIL 12I - Skin Fresheners 2
ZEA MAYS (CORN) OIL 12J - Other Skin Care Preps 24
ZEA MAYS (CORN) OIL 13A - Suntan Gels, Creams, and Liquids 1
ZEA MAYS (CORN) OIL 13B - Indoor Tanning Preparations 2
ZEA MAYS (CORN) OIL 13C - Other Suntan Preparations 3
ZEA MAYS (CORN) GERM OIL 01B - Baby Lotions, Oils, Powders, and Creams 3
ZEA MAYS (CORN) GERM OIL 01C - Other Baby Products 1
ZEA MAYS (CORN) GERM OIL 02A - Bath Oils, Tablets, and Salts 4
ZEA MAYS (CORN) GERM OIL 05A - Hair Conditioner 1
ZEA MAYS (CORN) GERM OIL 05E - Rinses (non-coloring) 1
ZEA MAYS (CORN) GERM OIL 05F - Shampoos (non-coloring) 1
ZEA MAYS (CORN) GERM OIL 10A - Bath Soaps and Detergents 2
ZEA MAYS (CORN) GERM OIL 10E - Other Personal Cleanliness Products 1
ZEA MAYS (CORN) GERM OIL 12A - Cleansing 9
ZEA MAYS (CORN) GERM OIL 12C - Face and Neck (exc shave) 6
CIR Panel Book Page 90
2010 FDA VCRP Raw Data
ZEA MAYS (CORN) GERM OIL 12D - Body and Hand (exc shave) 4
ZEA MAYS (CORN) GERM OIL 12F - Moisturizing 16
ZEA MAYS (CORN) GERM OIL 12J - Other Skin Care Preps 3
ZEA MAYS (CORN) GERM OIL 13B - Indoor Tanning Preparations 1
ZEA MAYS (CORN) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 1
PERSEA GRATISSIMA (AVOCADO) OIL 01B - Baby Lotions, Oils, Powders, and Creams 7
PERSEA GRATISSIMA (AVOCADO) OIL 01C - Other Baby Products 2
PERSEA GRATISSIMA (AVOCADO) OIL 02A - Bath Oils, Tablets, and Salts 23
PERSEA GRATISSIMA (AVOCADO) OIL 02B - Bubble Baths 1
PERSEA GRATISSIMA (AVOCADO) OIL 02D - Other Bath Preparations 1
PERSEA GRATISSIMA (AVOCADO) OIL 03A - Eyebrow Pencil 2
PERSEA GRATISSIMA (AVOCADO) OIL 03B - Eyeliner 3
PERSEA GRATISSIMA (AVOCADO) OIL 03C - Eye Shadow 1
PERSEA GRATISSIMA (AVOCADO) OIL 03D - Eye Lotion 12
PERSEA GRATISSIMA (AVOCADO) OIL 03E - Eye Makeup Remover 1
PERSEA GRATISSIMA (AVOCADO) OIL 03F - Mascara 2
PERSEA GRATISSIMA (AVOCADO) OIL 03G - Other Eye Makeup Preparations 3
PERSEA GRATISSIMA (AVOCADO) OIL 04E - Other Fragrance Preparation 7
PERSEA GRATISSIMA (AVOCADO) OIL 05A - Hair Conditioner 58
PERSEA GRATISSIMA (AVOCADO) OIL 05B - Hair Spray (aerosol fixatives) 4
PERSEA GRATISSIMA (AVOCADO) OIL 05C - Hair Straighteners 10
PERSEA GRATISSIMA (AVOCADO) OIL 05D - Permanent Waves 1
PERSEA GRATISSIMA (AVOCADO) OIL 05F - Shampoos (non-coloring) 26
PERSEA GRATISSIMA (AVOCADO) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 33
PERSEA GRATISSIMA (AVOCADO) OIL 05I - Other Hair Preparations 57
PERSEA GRATISSIMA (AVOCADO) OIL 07A - Blushers (all types) 2
PERSEA GRATISSIMA (AVOCADO) OIL 07C - Foundations 4
PERSEA GRATISSIMA (AVOCADO) OIL 07E - Lipstick 60
PERSEA GRATISSIMA (AVOCADO) OIL 07F - Makeup Bases 23
PERSEA GRATISSIMA (AVOCADO) OIL 07I - Other Makeup Preparations 14
PERSEA GRATISSIMA (AVOCADO) OIL 08A - Basecoats and Undercoats 1
PERSEA GRATISSIMA (AVOCADO) OIL 08B - Cuticle Softeners 2
PERSEA GRATISSIMA (AVOCADO) OIL 08C - Nail Creams and Lotions 1
PERSEA GRATISSIMA (AVOCADO) OIL 08D - Nail Extenders 1
PERSEA GRATISSIMA (AVOCADO) OIL 08F - Nail Polish and Enamel Removers 1
PERSEA GRATISSIMA (AVOCADO) OIL 08G - Other Manicuring Preparations 1
PERSEA GRATISSIMA (AVOCADO) OIL 10A - Bath Soaps and Detergents 30
PERSEA GRATISSIMA (AVOCADO) OIL 10E - Other Personal Cleanliness Products 13
PERSEA GRATISSIMA (AVOCADO) OIL 11A - Aftershave Lotion 2
PERSEA GRATISSIMA (AVOCADO) OIL 11E - Shaving Cream 4
PERSEA GRATISSIMA (AVOCADO) OIL 11F - Shaving Soap 2
PERSEA GRATISSIMA (AVOCADO) OIL 11G - Other Shaving Preparation Products 2
PERSEA GRATISSIMA (AVOCADO) OIL 12A - Cleansing 37
PERSEA GRATISSIMA (AVOCADO) OIL 12B - Depilatories 1
PERSEA GRATISSIMA (AVOCADO) OIL 12C - Face and Neck (exc shave) 35
PERSEA GRATISSIMA (AVOCADO) OIL 12D - Body and Hand (exc shave) 95
PERSEA GRATISSIMA (AVOCADO) OIL 12E - Foot Powders and Sprays 1
PERSEA GRATISSIMA (AVOCADO) OIL 12F - Moisturizing 199
PERSEA GRATISSIMA (AVOCADO) OIL 12G - Night 20
PERSEA GRATISSIMA (AVOCADO) OIL 12H - Paste Masks (mud packs) 14
PERSEA GRATISSIMA (AVOCADO) OIL 12I - Skin Fresheners 2
PERSEA GRATISSIMA (AVOCADO) OIL 12J - Other Skin Care Preps 46
PERSEA GRATISSIMA (AVOCADO) OIL 13A - Suntan Gels, Creams, and Liquids 5
PERSEA GRATISSIMA (AVOCADO) OIL 13B - Indoor Tanning Preparations 8
PERSEA GRATISSIMA (AVOCADO) OIL 13C - Other Suntan Preparations 3
TRITICUM VULGARE (WHEAT) GERM OIL 01A - Baby Shampoos 1
TRITICUM VULGARE (WHEAT) GERM OIL 01B - Baby Lotions, Oils, Powders, and Creams 6
TRITICUM VULGARE (WHEAT) GERM OIL 01C - Other Baby Products 2
TRITICUM VULGARE (WHEAT) GERM OIL 02A - Bath Oils, Tablets, and Salts 1
CIR Panel Book Page 91
2010 FDA VCRP Raw Data
TRITICUM VULGARE (WHEAT) GERM OIL 02D - Other Bath Preparations 1
TRITICUM VULGARE (WHEAT) GERM OIL 03C - Eye Shadow 1
TRITICUM VULGARE (WHEAT) GERM OIL 03D - Eye Lotion 5
TRITICUM VULGARE (WHEAT) GERM OIL 03E - Eye Makeup Remover 1
TRITICUM VULGARE (WHEAT) GERM OIL 03F - Mascara 3
TRITICUM VULGARE (WHEAT) GERM OIL 03G - Other Eye Makeup Preparations 2
TRITICUM VULGARE (WHEAT) GERM OIL 04E - Other Fragrance Preparation 2
TRITICUM VULGARE (WHEAT) GERM OIL 05A - Hair Conditioner 48
TRITICUM VULGARE (WHEAT) GERM OIL 05B - Hair Spray (aerosol fixatives) 4
TRITICUM VULGARE (WHEAT) GERM OIL 05C - Hair Straighteners 3
TRITICUM VULGARE (WHEAT) GERM OIL 05F - Shampoos (non-coloring) 30
TRITICUM VULGARE (WHEAT) GERM OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 30
TRITICUM VULGARE (WHEAT) GERM OIL 05H - Wave Sets 1
TRITICUM VULGARE (WHEAT) GERM OIL 05I - Other Hair Preparations 25
TRITICUM VULGARE (WHEAT) GERM OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests)9
TRITICUM VULGARE (WHEAT) GERM OIL 06D - Hair Shampoos (coloring) 1
TRITICUM VULGARE (WHEAT) GERM OIL 06F - Hair Lighteners with Color 3
TRITICUM VULGARE (WHEAT) GERM OIL 06G - Hair Bleaches 6
TRITICUM VULGARE (WHEAT) GERM OIL 06H - Other Hair Coloring Preparation 1
TRITICUM VULGARE (WHEAT) GERM OIL 07C - Foundations 1
TRITICUM VULGARE (WHEAT) GERM OIL 07E - Lipstick 29
TRITICUM VULGARE (WHEAT) GERM OIL 07I - Other Makeup Preparations 5
TRITICUM VULGARE (WHEAT) GERM OIL 08B - Cuticle Softeners 1
TRITICUM VULGARE (WHEAT) GERM OIL 08C - Nail Creams and Lotions 1
TRITICUM VULGARE (WHEAT) GERM OIL 10A - Bath Soaps and Detergents 16
TRITICUM VULGARE (WHEAT) GERM OIL 10E - Other Personal Cleanliness Products 6
TRITICUM VULGARE (WHEAT) GERM OIL 11A - Aftershave Lotion 1
TRITICUM VULGARE (WHEAT) GERM OIL 12A - Cleansing 19
TRITICUM VULGARE (WHEAT) GERM OIL 12C - Face and Neck (exc shave) 42
TRITICUM VULGARE (WHEAT) GERM OIL 12D - Body and Hand (exc shave) 78
TRITICUM VULGARE (WHEAT) GERM OIL 12F - Moisturizing 75
TRITICUM VULGARE (WHEAT) GERM OIL 12G - Night 15
TRITICUM VULGARE (WHEAT) GERM OIL 12H - Paste Masks (mud packs) 7
TRITICUM VULGARE (WHEAT) GERM OIL 12J - Other Skin Care Preps 39
TRITICUM VULGARE (WHEAT) GERM OIL 13A - Suntan Gels, Creams, and Liquids 2
TRITICUM VULGARE (WHEAT) GERM OIL 13B - Indoor Tanning Preparations 1
TRITICUM VULGARE (WHEAT) GERM OIL 13C - Other Suntan Preparations 3
CIR Panel Book Page 92
Personal CareProducts CouncilCommitted to Safety,Quality & Innovation
Memorandum
TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (CW)
FROM: CIR Science and Support Committee
DATE: May 13, 2010
SUBJECT: Concentration of Use Plant Oils March 2010 Survey
Concentration of Use Vegetable Oil and Hydrogenated Vegetable Oil
Concentration of Use Major Plant Seed Oils March 2010 Survey
Concentration of Use Minor Plant Seed Oils March 2010 Survey
1101 17th Street, N.W., Suite 3O0 Washington, D.C. 20036-4702 202.331.1770 202.331 .1969 (fax) www.personcilcarecouncil.org CIR Panel Book Page 93
Concentration of Use - Vegetable Oil and Hydrogenated Vegetable Oil
Ingredient Product Category Concentration of Use
Vegetable Oil Bath oils, tablets and salts 0002-0.02%
Vegetable Oil Eyebrow pencil 0.02-0.05%
Vegetable Oil Eye shadow 0.01-11%
Vegetable Oil Eye lotion 0.05-2%
Vegetable Oil Mascara 2%
Vegetable Oil Perfumes 0.0005-0.02%
Vegetable Oil Hair conditioners 2%
Vegetable Oil Pennanent waves 0.02%
Vegetable Oil Tonics, dressings and other hair grooming aids 0.07%
Vegetable Oil Other hair preparations (noncoloring) 0.02%
Vegetable Oil Foundations 0.04-5%
Vegetable Oil Lipstick 0.03-11%
Vegetable Oil Other makeup preparations 0.005-0.09%
Vegetable Oil Cuticle softeners 2%
Vegetable Oil Bath soaps and detergents 0.03-2%
Vegetable Oil Skin cleansing (cold creams, cleansing lotions, 0.1%liquids and pads)
Vegetable Oil Depilatories 31%
Vegetable Oil Face and neck creams, lotions and powders 0.3-2%
Vegetable Oil Body and hand creams, lotions and powders 0.2-5%
Vegetable Oil Moisturizing creams, lotions and powders 0.05%
Vegetable Oil Night creams, lotions and powders 0.05-2%
Vegetable Oil Other skin care preparations 0.0005-8%
Vegetable Oil Other suntan preparations 0.03-1%
Hydrogenated Vegetable Oil Other bath preparations 0.5%
Hydrogenated Vegetable Oil Eyebrow pencil 7-31%
Hydrogenated Vegetable Oil Eyeliner 10-49%
Hydrogenated Vegetable Oil Eye shadow 0.4-25%
Hydrogenated Vegetable Oil Eye lotion 0.2-1 1%
Hydrogenated Vegetable Oil Mascara 0.008-8%
Page 1 of 2
CIR Panel Book Page 94
Information collected in 2010Table prepared May 12, 2010
Hydrogenated Vegetable Oil Hair conditioners 0.0007%
Hydrogenated Vegetable Oil Shampoos (noncoloring) 0.0005%
Hyclrogenated Vegetable Oil Tonics, dressings and other hair grooming aids 0.09%
Hydrogenated Vegetable Oil Hair dyes and colors (all types requiring 0.0004%caution statement and patch test)
Hydrogenated Vegetable Oil Hair tints 1%
Hydrogenated Vegetable Oil Blushers (all types) 2-6%
Hydrogenated Vegetable Oil Face powders 1%
Hydrogenated Vegetable Oil Foundations 0.2-57%
Hydrogenated Vegetable Oil Lipstick 0.8-60%
Hydrogenated Vegetable Oil Other makeup preparations 0.02-31%
Hydrogenated Vegetable Oil Cuticle softeners 0.2%
Hydrogenated Vegetable Oil Bath soaps and detergents 2%
Hydrogenated Vegetable Oil Other personal cleanliness products 4%
Hydrogenated Vegetable Oil Shaving cream (aerosol, brushless and lather) 0.002%
Hydrogenated Vegetable Oil Skin cleansing (cold creams, cleansing lotions 8%liquids and pads)
Hydrogenated Vegetable Oil Depilatories 6%
Hydrogenated Vegetable Oil Face and neck cream, lotions and powders 3-20%
Hydrogenated Vegetable Oil Body and hand creams, lotions and powders 0.01-14%
Hydrogenated Vegetable Oil Foot powders and sprays 3%
Hydrogenated Vegetable Oil Night creams, lotions and powders 0.0005-0.2%
Hydrogenated Vegetable Oil Paste masks (mud packs) 8%
Hydrogenated Vegetable Oil Other skin care preparations 2-8%
Hydrogenated Vegetable Oil Suntan gels, creams and liquids 3%
Hydrogenated Vegetable Oil Other suntan preparations 12%
Page 2 of 2
CIR Panel Book Page 95
Concentration of Use Major Plant Seed Oils March 2010 SurveyBrassica Campestris (Rapeseed) Seed Oil, Brassica Campestris (Rapeseed) Oil Unsaponifiables, Hydrogenated RapeseedOil, Potassium Rapessedate, Rapeseed Acid, Sodium Rapseedate, Canola Oil, Canola Oil Unsaponifables, Hydrogenated
Canola Oil, Glycine Soja (Soybean) Oil, Glycine Soja (Soybean) Oil Unsaponifiables, Hydrogenated Soybean Oil, SoyAcid, Potassium Sovate, Sodium Soyate. Hetianthus Annuus (Sunflower) Seed Oil, Helianthus Annuns (Sunflower) Seed
Oil Unsaponifiables, Hydrogenated Sunflower Seed Oil, Sunflower Seed Acid, Olea Europaea (Olive) Fruit Oil, OleaEuropaea (Olive) Oil Unsaponifiables, Hydrogenated Olive Oil, 1-lydrogenated Olive Oil Unsaponifiables, Olive Acid, Olea
Europea (Olive) Husk Oil, Olea Europeae (Olive) Oil Unsaponifiables, Potassium Olivate, Sodium Olivate*
Ingredient Product Category Concentration of Use
Brassica Campestris (Rapeseed) Oil Shampoos (noncoloring) 0.1%
Brassica Campestris (Rapeseed) Oil Lipstick 9%
Brassica Campestris (Rapeseed) Oil Preshave lotions (all types) 1%
Brassica Campestris (Rapeseed) Oil Skin cleansing (cold creams, cleansing lotions, 0.01-10%liquids and pads)
Brassica Campestris (Rapeseed) Oil Face and neck creams, lotions, and powders 2-17%
Brassica Campestris (Rapeseed) Oil Body and hand creams, lotions, and powders 0.0 1-9%
Brassica Campestris (Rapeseed) Oil Moisturizing crams, lotions and powders 3%
Brassica Campestris (Rapeseed) Oil Night creams, lotions and powders 3%
Brassica Campestris (Rapeseed) Oil Paste masks (mud packs) 1%
Brassica Campestris (Rapeseed) Oil Other skin care preparations 0.07%
Brassica Campestris (Rapeseed) Oil Other suntan preparations 0,007%
Hydrogenated Rapeseed Oil Mascara 2%
Hydrogenated Rapeseed Oil Foundations 0.3%
Hydrogenated Rapeseed Oil Skin cleansing (cold creams, cleansing lotions, 4%liquids and pads)
Hydrogenated Rapeseed Oil Other skin care preparations 0.8%
Canola Oil Bath oils, tablets, and salts 1-33%
Canola Oil Eye shadow 0.03%
Canola Oil Eye lotion 0.002%
Canola Oil Colognes and toilet waters 0.02%
Canola Oil Perfumes 17%
Canola Oil Other fragrance preparations 0.0002%
Canola Oil Hair conditioners 0.9-24%
Canola Oil Hair sprays (aerosol fixatives) 0.006%
Canola Oil Shampoos (noncoloring) 0.06%
Canola Oil Tonics, dressings, and other hair grooming aids 0.1-1 1%
Page 1 of 9
CIR Panel Book Page 96
Canola Oil Foundations 0.02%
Canola Oil Lipstick 0.3-70%
Canola Oil Nail clealus and lutiuns
Canola Oil Bath soaps and detergents 02-1%
Canola Oil Other personal cleanliness products 0.02%
Canola Oil Skin cleansing (cold creams, cleansing lotions, 2%liquids and pads)
Canola Oil Depilatories 002-0.06%
Canola Oil Face and neck creams, lotions, and powders 1-5%
Canola Oil Body and hand creams, lotions, and powders 28-73%
Canola Oil Paste masks (mud packs) 3%
Canola Oil Other skin care preparations 0.03-5%
Canola Oil Other suntan preparations 0.09%
Canola Oil Unsaponifiables Hair conditioners 0.00 1%
Canola Oil Unsaponifiables Shampoos (noncoloring) 0.001%
Glycine Soja (Soybean) Oil Baby lotions, oils, powders and creams 2%
Glycine Soja (Soybean) Oil Bath oils, tablets, and salts 0,1-78%
Glycine Soja (Soybean) Oil Eyebrow pencil 0.1-1%
Glycine Soja (Soybean) Oil Eyeliner 0.1-1%
Glycine Soja (Soybean) Oil Eye shadow 0.005-0.8%
Glycine Soja (Soybean) Oil Eye lotion 0.2-2%
Glycine Soja (Soybean) Oil Mascara 0.04 - 2%
Glycine Soja (Soybean) Oil Perfumes 0.03-0.5%
Glycine Soja (Soybean) Oil Other fragrance preparations 0.04%
Glycine Soja (Soybean) Oil Hair conditioners 0.0002-30%
Glycine Soja (Soybean) Oil Permanent waves 95%
Glycine Soja (Soybean) Oil Rinses (noncoloring) 0.02%
Glycine Soja (Soybean) Oil Shampoos (noncoloring) 0.0 1-0.2%
Glycine Soja (Soybean) Oil Tonics, dressings, and other hair grooming aids 0.2-66%
Glycine Soja (Soybean) Oil Blushers (all types) 0.005-0.7%
Glycine Soja (Soybean) Oil Face powders 0.005%
Glycine Soja (Soybean) Oil Foundations 0.0 1-1%
Page 2 of 9
CIR Panel Book Page 97
Glycine Soja (Soybean) Oil Leg and body paints 0.3%
Glycine Soja (Soybean) Oil Lipstick 0.06-4%
Glycine Soja (S%heaa) Oil NIakeup has 0.0
Glycine Soja (Soybean) Oil Nail creams and lotions 2-95%
Glycine Soja (Soybean) Oil Nail polish and enamel 0.02%
Glycine Soja (Soybean) Oil Nail polish and enamel removers 0.02%
Glycine Soja (Soybean) Oil Bath soaps and detergents 0.0 1-52%
Glycine Soja (Soybean) Oil Deodorants (underarm) 0.0 1-0.5%
Glycine Soja (Soybean) Oil Preshave lotions (all types) 8%
Glycine Soja (Soybean) Oil Other shaving preparations 93%
Glycine Soja (Soybean) Oil Skin cleansing (cold creams, cleansing lotions, 0.2-9%liquids and pads)
Glycine Soja (Soybean) Oil Depilatories 0.5%
Glycine Soja (Soybean) Oil Face and neck creams, lotions, and powders 0.0005-4%
Glycine Soja (Soybean) Oil Body and hand creams, lotions, and powders 0.1-75%
Glycine Soja (Soybean) Oil Foot powders and sprays 0.05%
Glycine Soja (Soybean) Oil Moisturizing creams, lotions and powders 0.1-94%
Glycine Soja (Soybean) Oil Night creams, lotions and powders 0.008-4%
Glycine Soja (Soybean) Oil Paste masks (mud packs) 0.008-1%
Glycine Soja (Soybean) Oil Other skin care preparations 0.04-49%
Glycine Soja (Soybean) Oil Suntan gels, creams, and liquids 1%
Glycine Soja (Soybean) Oil Indoor tanning preparations 1%
Glycine Soja (Soybean) Oil Other suntan preparations 0.2-0.3%
Glycine Soja (Soybean) Oil Foundations 0.03-0.1%Unsaponifiables
Glycine Soja (Soybean) Oil Face and neck creams, lotions, and powders 0,2%Unsaponifiables
Glycine Soja (Soybean) Oil Moisturizing creams, lotions and powders 0.0001%Unsaponifiables
Hydrogenated Soybean Oil Bath oils, tablets and salts 42%
Hydrogenated Soybean Oil Bubble baths 5%
Hydrogenated Soybean Oil Eyebrow pencil 7%
Hydrogenated Soybean Oil Eyeliner 5%
Page 3 of 9
CIR Panel Book Page 98
Hydrogenated Soybean Oil Eye shadow 0.03-2%
Hydrogenated Soybean Oil Hair conditioners 0.1%
HydrogcLttcl Soybcati Oil Bliislicrs (all ps) I 1
Hydrogenated Soybean Oil Face powders 0.07%
Hydrogenated Soybean Oil Foundations 0.09-15%
Hydrogenated Soybean Oil Lipstick 0.1-39%
Hydrogenated Soybean Oil Makeup bases 4%
Hydrogenated Soybean Oil Other makeup preparations 0.01%
Hydrogenated Soybean Oil Basecoats and undercoats (manicuring preparations) 0.001%
Hydrogenated Soybean Oil Cuticle softeners 0.05-2%
Hydrogenated Soybean Oil Nail creams and lotions 25%
Hydrogenated Soybean Oil Nail polish and enamel 0.00 1-2%
Hydrogenated Soybean Oil Bath soaps and detergents 0.05%
Hydrogenated Soybean Oil Other personal cleanliness products 6%
Hydrogenated Soybean Oil Skin cleansing (cold creams, cleansing lotions, 0.2-15%liquids and pads)
Hydrogenated Soybean Oil Depilatories 0.1%
Hydrogenated Soybean Oil Face and neck creams, lotions, and powders 2%
Hydrogenated Soybean Oil Body and hand creams, lotions, and powders 0.1-5%
Hydrogenated Soybean Oil Moisturizing creams, lotions and powders 0.4-5%
Hydrogenated Soybean Oil Night creams, lotions and powders 0.5-0.8%
Hydrogenated Soybean Oil Paste masks (mud packs) 7%
Hydrogenated Soybean Oil Other skin care preparations 4-21%
Hydrogenated Soybean Oil Indoor tanning preparations 1-2%
Hydrogenated Soybean Oil Other suntan preparations 0.5%
Helianthus Annuus (Sunflower) Seed Oil Other baby products 0.2%
Helianthus Annuus (Sunflower) Seed Oil Bath oils, tablets, and salts 0.05-75%
Helianthus Annuus (Sunflower) Seed Oil Bubble baths 0.2%
Helianthus Annuus (Sunflower) Seed Oil Eyebrow pencil 0.1%
Helianthus Annuus (Sunflower) Seed Oil Eyeliner 0.01-19%
Helianthus Annuus (Sunflower) Seed Oil Eye Shadow 0.002-0.3%
Helianthus Annuus (Sunflower) Seed Oil Eye lotion 0.0 1-5%
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Helianthus Annuus (Sunflower) Seed Oil Eye makeup remover 0.0005-2%
Helianthus Annuus (Sunflower) Seed Oil Mascara 0.1%
1—lelianiluis Aiinuns (Suniio\ver) Seed Oil Colngnns and oi Lt waters 0.027
Helianthus Annuus (Sunflower) Seed Oil Perfumes 0.03%
Helianthus Annuus (Sunflower) Seed Oil Other fragrance preparations 0.1-85%
Helianthus Annuus (Sunflower) Seed Oil Hair conditioners 0.000007-92%
Helianthus Annuus (Sunflower) Seed Oil Hair sprays (aerosol fixatives) 0.06-0.07%
Helianthus Annuus (Sunflower) Seed Oil Rinses (noncoloring) 0.1%
Helianthus Annuus (Sunflower) Seed Oil Shampoos (noncoloring) 0.00007- 0.3%
Helianthus Annuus (Sunflower) Seed Oil Tonics, dressings, and other hair grooming aids 0.1-83%
Helianthus Annuus (Sunflower) Seed Oil Other hair preparations (noncoloring) 0.3-15%
Helianthus Annuus (Sunflower) Seed Oil Hair dyes and colors 0.8%
Helianthus Annuus (Sunflower) Seed Oil Hair tints 20-35%
Helianthus Annuus (Sunflower) Seed Oil Hair bleaches 0.03%
Helianthus Annuus (Sunflower) Seed Oil Other hair coloring preparations 2%
Helianthus Annuus (Sunflower) Seed Oil Blushers (all types) 0.1-10%
Helianthus Annuus (Sunflower) Seed Oil Face powders 0.0 1-0.5%
Helianthus Annuus (Sunflower) Seed Oil Foundations 0.1-16%
Helianthus Annuus (Sunflower) Seed Oil Lipstick 0.08-41%
Helianthus Annuus (Sunflower) Seed Oil Makeup bases 0.1%
Helianthus Annuus (Sunflower) Seed Oil Other makeup preparations 2%
Helianthus Annuus (Sunflower) Seed Oil Cuticle softeners 30%
Helianthus Annuus (Sunflower) Seed Oil Nail polish and enamel removers 0.05%
Helianthus Annuus (Sunflower) Seed Oil Other manicuring preparations 0.4%
Helianthus Annuus (Sunflower) Seed Oil Bath soaps and detergents 0.003-10%
Helianthus Annuus (Sunflower) Seed Oil Deodorants (underarm) 0.0003-4%
Helianthus Annuus (Sunflower) Seed Oil Other personal cleanliness products 0.02-6%
Helianthus Annuus (Sunflower) Seed Oil Preshave lotions (all types) 0.2%
Helianthus Annuus (Sunflower) Seed Oil Shaving cream (aerosol, brushless, and lather) 0.1-0.5%
Helianthus Annuus (Sunflower) Seed Oil Skin cleansing (cold creams, cleansing lotions, 0.03-35%liquids and pads)
Helianthus Annuus (Sunflower) Seed Oil Depilatories 0.07-2%
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Helianthus Annuus (Sunflower) Seed Oil Face and neck creams, lotions, and powders 0.0 1-28%
Helianthus Annuus (Sunflower) Seed Oil Body and hand creams, lotions, and powders 0.00 1-96%
1-lelianthus .•\niuus (Sunflower) Seed OP Bud’ and hand sprays 00002—I %
Helianthus Annuus (Sunflower) Seed Oil Moisturizing creams, lotions and powders 0.1-3%
Helianthus Annuus (Sunflower) Seed Oil Night creams, lotions and powders 0.05-48%
Helianthus Annuus (Sunflower) Seed Oil Paste masks (mud packs) 0.3-16%
Helianthus Annuus (Sunflower) Seed Oil Skin fresheners 0.1%
Helianthus Annuus (Sunflower) Seed Oil Other skin care preparations 0.02-80%
Helianthus Annuus (Sunflower) Seed Oil Suntan gels, creams, and liquids 1-23%
Helianthus Annuus (Sunflower) Seed Oil Indoor tanning preparations 0.002%
Helianthus Annuus (Sunflower) Seed Oil Other suntan preparations 0.1%
Helianthus Annuus (Sunflower) Seed Eyeliner 0.02%Unsaponifiables
Helianthus Annuus (Sunflower) Seed Blushers (all types) 0.1%Unsaponifiables
Helianthus Annuus (Sunflower) Seed Other personal cleanliness products 0.02%Unsaponifiables
Helianthus Annuus (Sunflower) Seed Face and neck creams, lotions, and powders 2%Unsaponifiables
Helianthus Annuus (Sunflower) Seed Body and hand creams, lotions, and powders 0.02%Unsaponifiables
Helianthus Annuus (Sunflower) Seed Night creams, lotions and powders 0.01-2%Unsaponifiables
Helianthus Annuus (Sunflower) Seed Other skin care preparations 0.005%Unsaponifiables
Hydrogenated Sunflower Seed Oil Eyeliner 7%
Hydrogenated Sunflower Seed Oil Hair tints 15-35%
Hydrogenated Sunflower Seed Oil Lipstick 6%
Hydrogenated Sunflower Seed Oil Skin cleansing (cold creams, cleansing lotions, 15-35%liquids and pads)
Olea Europaea (Olive) Fruit Oil Baby lotions, oils, powders and creams 0.2%
Olea Europaea (Olive) Fruit Oil Bath oils, tablets, and salts 2%
Olea Europaea (Olive) Fruit Oil Bubble baths 0.9%
Olea Europaea (Olive) Fruit Oil Other bath preparations 17%
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Olea Europaea (Olive) Fruit Oil Eyeliner 0.1-17%
Olea Europaea (Olive) Fruit Oil Eye shadow 0.1-2%
Olca Eur parI (Olive) Fruit Oil E. lotion 1-3%
Olea Europaea (Olive) Frut Oil Eye makeup remover 0.0 1-10%
Olea Europaea (Olive) Fruit Oil Mascara 0.004-0.8%
Olea Europaea (Olive) Fruit Oil Perfumes 0.2-5%
Olea Europaea (Olive) Fruit Oil Hair conditioners 0.03-94%
Olea Europaea (Olive) Fruit Oil Hair sprays (aerosol fixatives) 3%
Olea Europaea (Olive) Fruit Oil Hair straighteners 0.01-0.5%
Olea Europaea (Olive) Fruit Oil Rinses (noncoloring) 0.01%
Olea Europaea (Olive) Fruit Oil Shampoos (noncoloring) 0.006-0.5%
Olea Europaea (Olive) Fruit Oil Tonics, dressings, arid other hair grooming aids 0.01-15%
Olea Europaea (Olive) Fruit Oil Other hair preparations (noncoloring) 1%
Olea Europaea (Olive) Fruit Oil Hair dyes and colors (all types requiring caution 0.2%statement and patch test)
Olea Europaea (Olive) Fruit Oil Hair bleaches 0.2%
Olea Europaea (Olive) Fruit Oil Other hair coloring preparations 0.5%
Olea Europaea (Olive) Fruit Oil Blushers (all types) 0.1-26%
Olea Europaea (Olive) Fruit Oil Face powders 0.08-2%
Olea Europaea (Olive) Fruit Oil Foundations 0.1-44%
Olea Europaea (Olive) Fruit Oil Leg and body paints 32%
Olea Europaea (Olive) Fruit Oil Lipstick 0.7-26%
Olea Europaea (Olive) Fruit Oil Makeup bases 49%
Olea Europaea (Olive) Fruit Oil Rouges 0.5%
Olea Europaea (Olive) Fruit Oil Other makeup preparations 0.4%
Olea Europaea (Olive) Fruit Oil Basecoats and undercoats (manicuring preparations) 0.00 1%
Olea Europaea (Olive) Fruit Oil Cuticle softeners 1-2%
Olea Europaea (Olive) Fruit Oil Nail creams and lotions 3%
Olea Europaea (Olive) Fruit Oil Other manicuring preparations 40%
Olea Europaea (Olive) Fruit Oil Bath soaps and detergents 0.0005-3%
Olea Europaea (Olive) Fruit Oil Deodorants (underarm) 0.02-0.1%
Olea Europaea (Olive) Fruit Oil Other personal cleanliness products 0.00 1-0.05%
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Olea Europaea (Olive) Fruit Oil Aftershave lotions 0.5%
Olea Europaea (Olive) Fruit Oil Shaving cream (aerosol, brushless, and lather) 0.007-0.1%
QIL’a F ropnca (Olive) Fruit Oil Skin cL’nns ing (cold creams. clennsing lotions. 0.01—10%liquids and pads)
Olea Europaea (Olive) Fruit Oil Depilatories 0.1%
Olea Europaea (Olive) Fruit Oil Face and neck creams, lotions, and powders 0.03-50%
Olea Europaea (Olive) Fruit Oil Body and hand creams, lotions, and powders 0.03-100%
Olea Europaea (Olive) Fruit Oil Foot powders and sprays 3%
Olea Europaea (Olive) Fruit Oil Moisturizing creams, lotions and powders 0.05-3%
Olea Europaea (Olive) Fruit Oil Night creams, lotions and powders 0.005-1%
Olea Europaea (Olive) Fruit Oil Paste masks (mud packs) 0.0005-3%
Olea Europaea (Olive) Fruit Oil Other skin care preparations 0.05-33%
Olea Europaea (Olive) Fruit Oil Suntan gels, creams, and liquids 0.1%
Olea Europaea (Olive) Fnut Oil Indoor tanning preparations 1%
Olea Europaea (Olive) Fruit Oil Other suntan preparations 20%
Olea Europaea (Olive) Oil Unsaponifiables Baby lotions, oils, powders and creams 0.04%
Olea Europaea (Olive) Oil Unsaponifiables Eye shadow 0.02-0.4%
Olea Europaea (Olive) Oil Unsaponifiables Eye lotion 0.3%
Olea Europaea (Olive) Oil Unsaponifiables Mascara 0.2%
Olea Europaea (Olive) Oil Unsaponifiables Other fragrance preparations 3%
Olea Europaea (Olive) Oil Unsaponifiables Hair conditioners 0.07-0.3%
Olea Europaea (Olive) Oil Unsaponifiables Shampoos (noncoloring) 0.2%
Olea Europaea (Olive) Oil Unsaponifiables Tonics, dressings, and other hair grooming aids 0.02%
Olea Europaea (Olive) Oil Unsaponifiables Foundations 2%
Olea Europaea (Olive) Oil Unsaponifiables Lipstick 0.08%
Olea Europaea (Olive) Oil Unsaponifiables Face and neck creams, lotions, and powders 0.3%
Olea Europaea (Olive) Oil Unsaponifiables Body and hand creams, lotions, and powders 0.01-0.04%
Olea Europaea (Olive) Oil Unsaponiflables Moisturizing creams, lotions and powders 0.0001%
Hydrogenated Olive Oil Baby lotions, oils, powders and creams 0.4%
Hydrogenated Olive Oil Eye Shadow 0.1-3%
Hydrogenated Olive Oil Eye lotion 0.1%
Hydrogenated Olive Oil Mascara 2%
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Hydrogenated Olive Oil Hair conditioners 0.01%
Hydrogenated Olive Oil Shampoos (noncoloring) 0.1%
tld: ‘genated Olive Oil Face po\\ders 12%
Hydrogenated Olive Oil Foundations 0.1-7%
Hydrogenated Olive Oil Lipstick 0.1-12%
Hydrogenated Olive Oil Nail creams and lotions 0.1%
Hydrogenated Olive Oil Bath soaps and detergents 0.0005%
Hydrogenated Olive Oil Face and neck creams, lotions, and powders 1-2%
Hydrogenated Olive Oil Body and hand creams, lotions, and powders 0.1-1%
Hydrogenated Olive Oil Moisturizing creams, lotions and powders 0.2%
Hydrogenated Olive Oil Night creams, lotions and powders 0.1-0.5%
Hydrogenated Olive Oil Paste masks (mud packs) 0.1%
Hydrogenated Olive Oil Other skin care preparations 1%
Hydrogenated Olive Oil Indoor tanning preparations 0.1%
Hydrogenated Olive Oil Other suntan preparations 0.1%
Hydrogenated Olive Oil Unsaponifiables Eye shadow 2%
Hydrogenated Olive Oil Unsaponifiables Eye lotion 0.3%
Hydrogenated Olive Oil Unsaponifiables Foundations 0.05-3%
Hydrogenated Olive Oil Unsaponifiables Skin cleansing (cold creams, cleansing lotions, 5%liquids and pads)
Hydrogenated Olive Oil Unsaponifiables Face and neck creams, lotions, and powders 3%
Hydrogenated Olive Oil Unsaponifiables Body and hand creams, lotions, and powders 2%
Hydrogenated Olive Oil Unsaponifiables Night creams, lotions and powders 2%
Sodium Olivate Bath soaps and detergents 4-18%
*Ingredients included in the title of the table, but not found in the table were included in the survey, but no uses were reportedInformation collected in 2010Table prepared May 13, 2010
The following ingredients will be included in a later concentration of use survey: Hydrogenated Safflower Oil, PotassiumSafflowerate, Safflower Acid, Sodium Safflowerate, Elaeis Guineensis (Palm)Oil, Elaeis Guineensis (Palm) Kernel Oil,Hydrogenated Palm Oil, Hydrogenated Palm Kernel Oil, Palm Kernel Acid, Elaeis Guineensis (Palm) Butter, Elaeis OleiferaKernel Oil, Elaies (Palm) Oil, Palm Acid, Hydrogenated Palm Acid, Potassium Palmate, Potassium Hydrogentaed Pamlate,Potassium Hydrogenated Palmate, Potassium Palm Kernelate, Sodium Hydrogenated Palmate, Sodium Palmate, Sodium PalmKernelate, Gossypium Herbaceum (Cotton) Seed Oil, Cottonseed Acid, Hydrogenated Cottonseed Oil, Oryza Sativa (Rice) BranOil, Oryza Sativa (Rice) Germ Oil, Rice Bran Acid, Hydrogenated Rice Bran Oil, Oryza Sativa (Rice) Seed Oil, SesamumIndicum (Sesame) Seed Butter
Page 9 of 9
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Concentration of Use Minor Plant Seed Oils Mach 2010 SurveyActinidia Chinensis (Kiwi) Seed Oil, Adansonia Digitata Oil, Adansonia Digitata Seed Oil, Hydrogenated Adansonia
Digitata Seed Oil, Amaranthus Hypochondriacus Seed Oil, Arctium Lappa Seed Oil, Argania Spinosa Kernel Oil,Hydrogenated Argania Spinosa Kernel Oil, Astrocarym Murumuru Seed Butter, Sodium Astrocaryum Murumuruate,
Avena Sativa (Oat) Kernel Oil, Borago Officinalis Seed Oil, Brassica Oleracea Italica (Broccoli) Seed Oil, Camelina SativaSeed Oil, Hydrogenated Camelina Sativa Seed Oil, Camellia Oleifera Seed Oil, Hydrogenated Camellia Oleifera Seed Oil,
Camellia Sinensis Seed Oil, Carica Papaya Seed Oil, Caryocar Brasiliense Fruit Oil, Chenopodium Quinoa Seed Oil,Citrullus Lanatus (Watermelon) Seed Oil, Citrus Aurantifolia (Lime) Seed Oil, Hydrogenated Lime Seed Oil,
Hydrogenated Lime Seed Oil Unsaponifiables, Citrus Aurantium Dulcis (Orange) Seed Oil, Citrus Aurantium Dulcis(Orange) Seed Oil Unsaponifiables, Hydrogenated Orange Seed Oil, Hydrogenated Orange Seed Oil Unsaponifiables,
Citrus Grandis (Grapefruit) Seed Oil, Citrus Grandis (Grapefruit) Seed Oil Unsaponifiables, Citrus Paradisi (Grapefruit)Seed Oil, Hydrogenated Grapefruit Seed Oil, Hydrogenated Grapefruit Seed Oil Unsaponifiables, Citrus Limon (Lemon)Seed Oil, Coix Lacryma-Jobi (Job’s Tears) Seed Oil, Cucumis Sativus (Cucumber) Seed Oil, Cucurbita Fepo (Pumpkin)
Seed Oil, Hydrogenated Pumpkin Seed Oil, Cynara Cardunculus Seed Oil, Euterpe Oleracea Fruit Oil, Fragaria Ananassa(Strawberry) Seed Oil, Fragaria Chiloensis (Strawberry) Seed Oil, Fragaria Vesca (Strawberry) Seed Oil, Fragaria
Virginiana (Strawberry) Seed Oil, Guizotia Abyssinica Seed Oil, Irvingia Gabonensis Kernel Butter, Limnanthes Alba(Meadowfoam) Seed Oil, Hydrogenated Meadowfoam Seed Oil, Linum Usitatissimum (Linseed) Oil, Linseed Acid,
Mangifera Indica (Mango) Seed Oil, Mangifera Indica (Mango) Seed Butter, Sodium Mangoseedate, Moringa OleiferaSeed Oil, Moringa Pterygosperma Seed Oil, Oenothera Biennis (Evening Primrose) Oil, Hydrogenated Evening PrimroseOil, Orbignya Oleifera Seed Oil, Babassu Acid, Potassium Babassuate, Sodium Babassuate, Perilla Ocymoides Seed Oil,
Prunus Armeniaca (Apricot) Kernel Oil, Hydrogenated Apricot Kernel Oil, Hydrogenated Apricot Kernel OilUnsaponifiables, Prunus Armeniaca (Apricot) Kernel Oil Unsaponifiables, Prunus Avium (Sweet Cherry) Seed Oil,
Prunus Domestica Seed Oil, Prunus Persica (Peach) Kernel Oil, Hydrogenated Peach Kernel Oil, Pyrus Malus (Apple)Seed Oil, Ribes Nigrum (Black Currant) Seed Oil, Hydrogenated Black Currant Seed Oil, Ribes Rubrum (Currant) Seed
Oil, Rubus Idaeus (Raspberry) Seed Oil, Hydrogenated Raspberry Seed Oil, Sclerocarya Birrea Seed Oil, SilybumMarianum Seed Oil, Solanum Lycopersicum (Tomato) Seed Oil, Solanum Lycopersicum (Tomato) Fruit Oil, Theobroma
Cacao (Cocoa) Seed Butter, Sodium Cocoa Butterate, Theobroma Grandiflorum Seed Butter, Sodium TheobromoaGrandiflorum Seedate, Torreya Nucifera Seed Oil, Vaccinum Macrocarpon (Cranberry) Seed Oil, Hydrogenated
Cranberry Seed Oil, Vitis Vinifera (Grape) Seed Oil, Sodium Grapeseedate, Hydrogenated Grapeseed Oil*
Ingredient Product Category Concentrationof Use
Actinidia Chinensis (Kiwi) Seed Oil Hair conditioners 0.1%
Actinidia Chinensis (Kiwi) Seed Oil Shampoos (noncoloring) 0.1%
Adansonia Digitata Oil Lipstick 0.01%
Argania Spinosa Kernel Oil Bath oils, tablets, and salts 0.05%
Argania Spinosa Kernel Oil Eyebrow pencil 0.1%
Argania Spinosa Kernel Oil Eyeliner 0.1%
Argania Spinosa Kernel Oil Eye shadow 0.2%
Argania Spinosa Kernel Oil Eye lotion 1%
Argania Spinosa Kernel Oil Mascara 0.1%
Argania Spinosa Kernel Oil Hair conditioners 1%
Argania Spinosa Kernel Oil Hair sprays (aerosol fixatives) 0.0 1%
Argania Spiriosa Kernel Oil Shampoos (noncoloring) 0.1%
Argania Spinosa Kernel Oil Hair dyes and colors (all types requiring caution statement 0.1%and patch test)
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Argania Spinosa Kernel Oil Other hair coloring preparations 0.07%
Argariia Spinosa Kernel Oil Blushers (all types) 0.1%
Argania Spinosa Kernel Oil Lipstick 0.1-1%
Argania Spinosa Kernel Oil Nail polish and enamel 0.001-0.1%
Argania Spinosa Kernel Oil Bath soaps and detergents 0.00 1-2%
Argania Spinosa Kernel Oil Deodorants (underarm) 0.001%
Argania Spinosa Kernel Oil Other personal cleanliness products 0.5%
Argania Spinosa Kernel Oil Aftershave lotions 0.005%
Argania Spinosa Kernel Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.002%pads)
Argania Spinosa Kernel Oil Face and neck creams, lotions, and powders 0.5-3%
Argania Spinosa Kernel Oil Body and hand creams, lotions, and powders 4-10%
Argania Spinosa Kernel Oil Moisturizing creams, lotions and powders 0.04%
Argania Spinosa Kernel Oil Night creams, lotions and powders 0.04-0.1%
Argania Spinosa Kernel Oil Other skin care preparations 2-3%
Astrocaryum Murumuru Seed Butter Eyeliner 0.06%
Astrocaryum Murumum Seed Butter Eye shadow 0.2%
Astrocaryum Murumuru Seed Butter Eye lotion 0.5%
Astrocaryum Murumuru Seed Butter Hair conditioners 0.00 1-0.2%
Astrocaryum Murumuru Seed Butter Shampoos (noncoloring) 0.09%
Astrocaryum Murumuru Seed Butter Tonics, dressings, and other hair grooming aids 0.2%
Astrocaryum Murumuru Seed Butter Foundations 1%
Astrocaryum Murumuru Seed Butter Lipstick 1-7%
Astrocaryum Murumuru Seed Butter Other makeup preparations 0.001%
Astrocaryum Murumuru Seed Butter Face and neck creams, lotions, and powders 1%
Astrocaryum Murumuru Seed Butter Body and hand creams, lotions, and powders 0.1-0.2%
Astrocaryum Murumuru Seed Butter Other skin care preparations 0.2%
Astrocaryum Murumuru Seed Butter Indoor tanning preparations 0.1%
Astrocaryum Murumuru Seed Butter Other suntan preparations 0.2%
Sodium Astrocaryum Murumuruate Bath soaps and detergents 0.002%
Sodium Astrocaryum Murumuruate Other shaving preparations products 0.005%
Sodium Astrocaryum Murumuruate Skin cleansing (cold creams, cleansing lotions, liquids and 0.002%pads)
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Avena Sative (Oat) Kernel Oil Baby lotions, oils, powders and creams 0.1%
Avena Sative (Oat) Kernel Oil Other baby products 0.1%
Avena Sative (Oat) Kernel Oil Eye lotion 0.2%
Avena Sative (Oat) Kernel Oil Shampoos (noncoloring) 0.1%
Avena Sative (Oat) Kernel Oil Lipstick 2%
Avena Sative (Oat) Kernel Oil Bath soaps and detergents 0.01-0.1%
Avena Sative (Oat) Kernel Oil Face and neck creams, lotions, and powders 0.5%
Avena Sative (Oat) Kernel Oil Body and hand crams, lotions, and powders 0.1-3%
Avena Sative (Oat) Kernel Oil Moisturizing creams, lotions and powders 0.1%
Avena Sative (Oat) Kernel Oil Night creams, lotions and powders 0.1-0.5%
Borago Officinalis Seed Oil Eye lotion 0.001-0.5%
Borago Officinalis Seed Oil Tonics, dressings and other hair grooming aids 0.1%
Borago Officinalis Seed Oil Lipstick 0.0 1%
Borago Officinalis Seed Oil Bath soaps and detergents 0.00 1%
Borago Officinalis Seed Oil Other personal cleanliness products 0.01%
Borago Officinalis Seed Oil Preshave lotions (all types) 0.04%
Borago Officinalis Seed Oil Shaving cream (aerosol, brushless, and lather) 0.5%
Borago Officinalis Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.1%pads)
Borago Officinalis Seed Oil Face and neck creams, lotions and powders 1%
Borago Officinalis Seed Oil Body and hand crams, lotions, and powders 0.05-1%
Borago Officinalis Seed Oil Body and hand sprays 0.1%
Borago Officinalis Seed Oil Moisturizing creams, lotions and powders 1%
Borago Officinalis Seed Oil Night creams, lotions and powders 0.5%
Borago Officinalis Seed Oil Other skin care preparations 0.5%
Borago Officinalis Seed Oil Indoor tanning preparations 0.5%
Brassica Oleracea Italica (Broccoli) Seed Hair conditioners 0.5%Oil
Brassica Oleracea Italica (Broccoli) Seed Shampoos (noncoloring) 0.00 1%Oil
Brassica Oleracea Italica (Broccoli) Seed Tonics, dressings, and other hair grooming aids 3%Oil
Camelina Sativa Seed Oil Eye lotion 0.05%
Camelina Sativa Seed Oil Hair conditioners 1%
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Camelina Sativa Seed Oil Lipstick 0.05-0.5%
Camelina Sativa Seed Oil Skin Cleansing (cold creams, cleansing lotions, liquids 0.002%and pads)
Camelina Sativa Seed Oil Face and neck creams, lotions, and powders 0.05-1%
Camelina Sativa Seed Oil Body and hand crams, lotions, and powders 0.1-0.9%
Camelina Sativa Seed Oil Moisturizing creams, lotions and powders 0.04%
Camelina Sativa Seed Oil Night creams, lotions and powders 0.04%
Camellia Oleifera Seed Oil Bath oils, tablets, and salts 0.05%
Camellia Oleifera Seed Oil Eye lotions 2%
Camellia Oleifera Seed Oil Tonics, dressings, and other hair grooming aids 2%
Camellia Oleifera Seed Oil Blushers (all types) 1%
Camellia Oleifera Seed Oil Lipstick 3%
Camellia Oleifera Seed Oil Bath soaps and detergents 0.01-0.1%
Camellia Oleifera Seed Oil Skin Cleansing (cold creams, cleansing lotions, liquids 0.003%and pads)
Camellia Oleifera Seed Oil Body and hand crams, lotions, and powders 0.0 1-1%
Camellia Oleifera Seed Oil Moisturizing creams, lotions and powders 0.08%
Camellia Oleifera Seed Oil Night creams, lotions and powders 0.08%
Camellia Oleifera Seed Oil Other suntan preparations 0.01%
Camellia Sinensis Seed Oil Shampoos (noncoloring) 0.1%
Camellia Sinensis Seed Oil Lipstick 0.1%
Camellia Sinensis Seed Oil Bath soaps and detergents 0.1%
Camellia Sinensis Seed Oil Deodorants (underarm) 0.1%
Camellia Sinensis Seed Oil Body and hand crams, lotions, and powders 0.1%
Camellia Sinensis Seed Oil Moisturizing creams, lotions and powders 0.1%
Camellia Sinensis Seed Oil Night creams, lotions and powders 0.1%
Carica Papaya Seed Oil Moisturizing creams, lotions and powders 0.1%
Carica Papaya Seed Oil Night creams, lotions and powders 0.1%
Caryocar Brasilinese Fruit Oil Lipstick 0.2%
Caryocar Brasilinese Fruit Oil Skin Cleansing (cold creams, cleansing lotions, liquids 0.0005%and pads)
Chenopodium Quinoa Seed Oil Hair rinses (coloring) 0.3%
Citrullus Lanatus (Watermelon) Seed Oil Face and neck creams, lotions, and powders 2%
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Citrus Grandis (Grapefruit) Seed Oil Hair conditioners 0.1%
Citrus Grandis (Grapefruit) Seed Oil Shampoos (noncoloring) 0.1%
Citrus Grandis (Grapefruit) Seed Oil Dentifrices (aerosol, liquid, pastes and powders) 0.1%
Citrus Grandis (Grapefruit) Seed Oil Mouthwashes and breath fresheners (liquids and sprays) 0.1%
Citrus Grandis (Grapefruit) Seed Oil Bath soaps and detergents 0.1%
Citrus Grandis (Grapefruit) Seed Oil Body and hand creams, lotions and powders 0.1%
Citrus Grandis (Grapefruit) Seed Oil Moisturizing creams, lotions and powders 0.1%
Citrus Grandis (Grapefruit) Seed Oil Night creams, lotions and powders 0.1%
Cucurbita Pepo (Pumpkin) Seed Oil Eye lotion 0.003%
Cucurbita Pepo (Pumpkin) Seed Oil Moisturizing creams, lotions and powders 0.1%
Cucurbita Pepo (Pumpkin) Seed Oil Night creams, lotions and powders 0.1%
Euterpe Oleracea Fruit Oil Bath oils, tablets, and salts 0.05%
Euterpe Oleracea Fruit Oil Eye lotion 0.5%
Euterpe Oleracea Fruit Oil Lipstick 0.002%
Euterpe Oleracea Fruit Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.00001%pads)
Euterpe Oleracea Fruit Oil Other suntan preparations 0.001%
Irvingia Gabonensis Kernel Butter Lipstick 0.003-0.3%
Irvingia Gabonensis Kernel Butter Face and neck creams, lotions, and powders 0.2-0.4%
Irvingia Gabonensis Kernel Butter Body and hand creams, lotions, and powders 0.03%
Limnanthes Alba (Meadowfoam) Seed Oil Bath oils, tablets, and salts 0.9%
Limnanthes Alba (Meadowfoam) Seed Oil Bubble baths 0.5%
Limnanthes Alba (Meadowfoam) Seed Oil Eyeliner 6-20%
Limnanthes Alba (Meadowfoam) Seed Oil Eye lotion 0.1-0.4%
Limnanthes Alba (Meadowfoam) Seed Oil Other fragrance preparations 3%
Limnanthes Alba (Meadowfoam) Seed Oil Hair conditioners 0.1-1%
Limnanthes Alba (Meadowfoam) Seed Oil Tonics, dressings, and other hair grooming aids 0.5%
Lirnnanthes Alba (Meadowfoam) Seed Oil Hair dyes and colors (all types requiring caution statement 0.2-2%and patch test)
Lininanthes Alba (Meadowfoam) Seed Oil Foundations 0.01-5%
Limnanthes Alba (Meadowfoam) Seed Oil Lipstick 0.6-26%
Lirnnanthes Alba (Meadowfoam) Seed Oil Cuticle softeners 0.5%
Limnanthes Alba (Meadowfoam) Seed Oil Bath soaps and detergents 0.01%
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Linmarithes Alba (Meadowfoam) Seed Oil Other personal cleanliness products 0.6%
Linmanthes Alba (Meadowfoam) Seed Oil Shaving cream (aerosol, brushless, and lather) 0.05%
Limnanthes Alba (Meadowfoam) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.002%pads)
Limnanthes Alba (Meadowfoam) Seed Oil Depilatories 2%
Linmanthes Alba (Meadowfoam) Seed Oil Face and neck creams, lotions, and powders 0.08-72%
Linmanthes Alba (Meadowfoam) Seed Oil Body and hand creams, lotions, and powders 0.005-27%
Limnanthes Alba (Meadowfoam) Seed Oil Body and hand sprays 0.1%
Limnanthes Alba (Meadowfoam) Seed Oil Moisturizing creams, lotions and powders 0.04- 74%
Limnanthes Alba (Meadowfoam) Seed Oil Night creams, lotions and powders 0.04-3%
Limnanthes Alba(Meadowfoam) Seed Oil Other skin care preparations 0.1-1%
Linum Usitatissimum (Linseed) Seed Oil Bath oils, tablets, and salts 0.02%
Linum Usitatissimum (Linseed) Seed Oil Bubble baths 0.2%
Linum Usitatissimum (Linseed) Seed Oil Eye lotion 0.01%
Linum Usitatissimum (Linseed) Seed Oil Mascara 10%
Linum Usitatissimum (Linseed) Seed Oil Hair conditioners 0.00 1-0.01%
Linum Usitatissimum (Linseed) Seed Oil Shampoos (noncoloring) 0.00 1-0.1%
Linum Usitatissimum (Linseed) Seed Oil Tonics, dressings, and other hair 0.01%
Linum Usitatissimum (Linseed) Seed Oil Lipstick 0.0 1%
Linum Usitatissimum (Linseed) Seed Oil Cuticle softeners 0.05%
Linum Usitatissimum (Linseed) Seed Oil Nail polish and enamel 0.002%
Linum Usitatissimum (Linseed) Seed Oil Bath soaps and detergents 0.003-0.4%
Linum Usitatissimum (Linseed) Seed Oil Deodorants (underarm) 0.05-0.1%
Linum Usitatissimum (Linseed) Seed Oil Aftershave lotions 4%
Linum Usitatissimum (Linseed) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.01-1%pads)
Linum Usitatissimum (Linseed) Seed Oil Face and neck creams, lotions, and powders 0.0 1-0.5%
Linum Usitatissimum (Linseed) Seed Oil Body and hand creams, lotions, and powders 0.1-0.2%
Linum Usitatissimum (Linseed) Seed Oil Moisturizing creams, lotions and powders 0.01-0.1%
Linum Usitatissimum (Linseed) Seed Oil Night creams, lotions and powders 0.1%
Mangifera Indica (Mango) Seed Oil Eyeliner 5%
Mangifera Indica (Mango) Seed Oil Hair conditioners 0.2%
Mangifera Indica (Mango) Seed Oil Hair straighteners 0.05%
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Mangifera Indica (Mango) Seed Oil Shampoos (noncoloring) 0.1%
Mangifera Indica (Mango) Seed Oil Tonics, dressings, and other hair grooming aids 0.01%
Mangifera Indica (Mango) Seed Oil Hair dyes and colors (all types requiring caution statement 0.05%and patch test)
Mangifera Indica (Mango) Seed Oil Lipstick 0.03-6%
Mangifera Indica (Mango) Seed Oil Bath soaps and detergents 0.1%
Mangifera Indica (Mango) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.003-0.5%pads)
Mangifera Indica (Mango) Seed Oil Face and neck creams, lotions, and powders 0.2-3%
Mangifera Indica (Mango) Seed Oil Body and hand creams, lotions, and powders 0.1-0.9%
Mangifera Indica (Mango) Seed Oil Moisturizing creams, lotions and powders 0.08%
Mangifera Indica (Mango) Seed Oil Night creams, lotions and powders 0.08%
Mangifera Indica (Mango) Seed Oil Other skin care preparations 1%
Mangifera Indica (Mango) Seed Oil Indoor tanning preparations 0.1%
Mangifera Indica (Mango) Seed Butter Eye shadow 0.02%
Mangifera Indica (Mango) Seed Butter Hair sprays (aerosol fixatives) 0.02%
Mangifera Indica (Mango) Seed Butter Shampoos (noncoloring) 0.1-0.5%
Mangifera Indica (Mango) Seed Butter Tonics, dressings, and other hair grooming aids 0.5%
Mangifera Indica (Mango) Seed Butter Blushers (all types) 0.02%
Mangifera Indica (Mango) Seed Butter Face powders 0.02%
Mangifera Indica (Mango) Seed Butter Foundations 0.02-5%
Mangifera Indica (Mango) Seed Butter Lipstick 1-5%
Mangifera Indica (Mango) Seed Butter Makeup bases 0.0 1%
Mangifera Indica (Mango) Seed Butter Cuticle softeners 0.5%
Mangifera Indica (Mango) Seed Butter Bath soaps and detergents 0.0005-0.1%
Mangifera Indica (Mango) Seed Butter Other personal cleanliness products 0.5%
Mangifera Indica (Mango) Seed Butter Shaving cream (aerosol, brushless and lather) 0.1%
Mangifera Indica (Mango) Seed Butter Depilatories 0.05%
Mangifera Indica (Mango) Seed Butter Face and neck creams, lotions, and powders 1-3%
Mangifera Indica (Mango) Seed Butter Body and hand creams, lotions, and powders 0.1-3%
Mangifera Indica (Mango) Seed Butter Moisturizing creams, lotions and powders 0.1%
Mangifera Indica (Mango) Seed Butter Night creams, lotions and powders 0.1%
Mangifera Indica (Mango) Seed Butter Other skin care preparations 0.04-2%
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Moringa Oleifera Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.0 1%pads)
Moringa Pterygosperma Seed Oil Eye lotion 3%
Moringa Pterygosperma Seed Oil Tonics, dressings, and other hair grooming aids 0.02%
Moringa Pterygosperma Seed Oil Other personal cleanliness products 0.003%
Moringa Pterygosperma Seed Oil Body and hand creams, lotions, and powders 0.004%
Oenothera Biennis (Evening Primrose) Oil Bubble baths 0.2%
Oenothera Biennis (Evening Primrose) Oil Eye lotion 0.00002-0.5%
Oenothera Biennis (Evening Primrose) Oil Eye makeup remover 0.002%
OenotheraBiennis (Evening Primrose) Oil Shampoos (noncoloring) 0.05-0.1%
Oenothera Biennis (Evening Primrose) Oil Tonics, dressings, and other hair grooming aids 0.1%
Oenothera Biennis (Evening Primrose) Oil Blushers (all types) 0.08%
Oenothera Biennis (Evening Primrose) Oil Foundations 58%
Oenothera Biennis (Evening Primrose) Oil Lipstick 0.1-15%
Oenothera Biennis (Evening Primrose) Oil Cuticle softeners 3%
Oenothera Biennis (Evening Primrose) Oil Nail creams and lotions 0.00 1-0.3%
Oenothera Biennis (Evening Primrose) Oil Nail polish and enamel 0.00 1%
Oenothera Biennis (Evening Primrose) Oil Bath soaps and detergents 0.1-0.2%
Oenothera Biennis (Evening Primrose) Oil Deodorants (underarm) 0.2%
Oenothera Biennis (Evening Primrose) Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.001-0.5%pads)
Oenothera Biennis (Evening Primrose) Oil Face and neck creams, lotions, and powders 0.08-2%
Oenothera Biennis (Evening Primrose) Oil Body and hand creams, lotions, and powders 0.1-2%
Oenothera Biennis (Evening Primrose) Oil Moisturizing creams, lotions and powders 0.04-0.1%
Oenothera Biennis (Evening Primrose) Oil Night creams, lotions and powders 0.008-3%
Oenothera Biennis (Evening Primrose) Oil Paste masks (mud packs) 0.1%
Oenothera Biennis (Evening Primrose) Oil Other skin care preparations 0.002-0.1%
Oenothera Biennis (Evening Primrose) Oil Indoor tanning preparations 0.003%
Oenothera Biennis (Evening Primrose) Oil Other suntan preparations 0.5%
Orbignya Oleifera Seed Oil Bath capsules 0.1%
Orbignya Oleifera Seed Oil Other bath preparations 0.0 1%
Orbignya Oleifera Seed Oil Eye shadow 0.5-0.6%
Orbignya Oleifera Seed Oil Hair conditioners 0.3-2%
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Orbignya Oleifera Seed Oil Hair sprays (aerosol fixatives) 0.02%
Orbignya Oleifera Seed Oil Tonics, dressings, and other hair grooming aids 0.1-1%
Orbignya Oleifera Seed Oil Foundations 0.5%
Orbignya Oleifera Seed Oil Lipstick 0.001-2%
Orbignya Oleifera Seed Oil Bath soaps and detergents 27%
Orbignya Oleifera Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.05%pads)
Orbignya Oleifera Seed Oil Body and hand creams, lotions, and powders 0.005-1%
Orbignya Oleifera Seed Oil Foot powders and sprays 2%
Orb ignya Oleifera Seed Oil Moisturizing creams, lotions and powders 0.1%
Orb ignya Oleifera Seed Oil Night creams, lotions and powders 0.1%
Orbignya Oleifera Seed Oil Other skin care preparations 4%
Orbignya Oleifera Seed Oil Suntan gels, creams, and liquids 0.0009%
Sodium Babassuate Bath soaps and detergents 8%
Prunus Armeniaca (Apricot) Kernel Oil Baby lotions, oils, powders and creams 4%
Prunus Armeniaca (Apricot) Kernel Oil Other bath preparations 7%
Prunus Armeniaca (Apricot) Kernel Oil Eye shadow 0.002-2%
Prunus Armeniaca (Apricot) Kernel Oil Eye lotion 0.2-9%
Prunus Armeniaca (Apricot) Kernel Oil Eye makeup remover 18%
Prunus Armeniaca (Apricot) Kernel Oil Mascara 0.002-0.05%
Prunus Armeniaca (Apricot) Kernel Oil Powders (dusting and talcum) (excluding aftershave) 0.1%
Prunus Armeniaca (Apricot) Kernel Oil Other fragrance preparations 0.02-1%
Prunus Armeniaca (Apricot) Kernel Oil Hair conditioners 0.003-89%
Prunus Armeniaca (Apricot) Kernel Oil Hair sprays (aerosol fixatives) 0.0009%
Prunus Armeniaca (Apricot) Kernel Oil Hair straighteners 0.0001%
Prunus Armeniaca (Apricot) Kernel Oil Rinses (noncoloring) 0.05%
Prunus Armeniaca (Apricot) Kernel Oil Shampoos (noncoloring) 0.1-0.5%
Prunus Armeniaca (Apricot) Kernel Oil Tonics, dressings, and other hair grooming aids 0.00 1-0.1%
Prunus Armeniaca (Apricot) Kernel Oil Hair dyes and colors (all types requiring caution statement 0.1%and patch test)
Prunus Armeniaca (Apricot) Kernel Oil Blushers (all types) 0.2%
Prunus Armeniaca (Apricot) Kernel Oil Face powders 0.1-0.6%
Prunus Armeniaca (Apricot) Kernel Oil Foundations 0.1-1%
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Prunus Armeniaca (Apricot) Kernel Oil Leg and body paints 0.001%
Prunus Armeniaca (Apricot) Kernel Oil Lipstick 0.00 1-5%
Prunus Armeniaca (Apricot) Kernel Oil Other makeup preparations 0.2%
Prunus Armeniaca (Apricot) Kernel Oil Basecoats and undercoats (manicuring preparations) 0.05%
Prunus Armeniaca (Apricot) Kernel Oil Cuticle softeners 0.05-5%
Prunus Armeniaca (Apricot) Kernel Oil Nail creams and lotions 2-40%
Prunus Armeniaca (Apricot) Kernel Oil Nail polish and enamel 0.05%
Prunus Armeniaca (Apricot) Kernel Oil Nail polish and enamel removers 0.002-0.01%
Prunus Armeniaca (Apricot) Kernel Oil Bath soaps and detergents 0.1-9%
Prunus Armeniaca (Apricot) Kernel Oil Deodorants (underarm) 0.003-0.1%
Prunus Armeniaca (Apricot) Kernel Oil Other personal cleanliness products 0.0 1-0.5%
Prunus Armeniaca (Apricot) Kernel Oil Aftershave lotions 0.5%
Prunus Armeniaca (Apricot) Kernel Oil Shaving cream (aerosol, brushless, and lather) 0.1%
Prunus Armeniaca (Apricot) Kernel Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.00 1-3%pads)
Prunus Armeniaca (Apricot) Kernel Oil Depilatories 0.00001-2%
Prunus Armeniaca (Apricot) Kernel Oil Face and neck creams, lotions, and powders 0.05-17%
Prunus Armeniaca (Apricot) Kernel Oil Body and hand creams, lotions, and powders 0.03-12%
Prunus Armeniaca (Apricot) Kernel Oil Moisturizing creams, lotions and powders 0.1-3%
Prunus Armeniaca (Apricot) Kernel Oil Night creams, lotions and powders 0.1-8%
Prunus Armeniaca (Apricot) Kernel Oil Paste masks (mud packs) 2%
Prunus Armeniaca (Apricot) Kernel Oil Skin fresheners 0.01%
Prunus Armeniaca (Apricot) Kernel Oil Other skin care preparations 0.0001-0.5%
Prunus Armeniaca (Apricot) Kernel Oil Suntan gels, creams, and liquids 0.0 1-0.05%
Prunus Armeniaca (Apricot) Kernel Oil Indoor tanning preparations 0.01-1%
Prunus Armeniaca (Apricot) Kernel Oil Other suntan preparations 0.0005%
Prunus Avium (Sweet) Cherry Seed Oil Bath soaps and detergents 0.0 1-0.02%
Pninus Domestica Seed Oil [ Preshave lotions (all types) 0.04%
Prunus Persica (Peach) Kernel Oil Bath oils, tablets, and salts 0.1%
Prunus Persica (Peach) Kernel Oil Other bath preparations 1%
Prunus Persica (Peach) Kernel Oil Other fragrance preparations 2%
Prunus Persica (Peach) Kernel Oil Hair dyes and colors (all types requiring caution statement 0.1%and patch test)
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Prunus Persica (Peach) Kernel Oil Lipstick 0.04-22%
Prunus Persica (Peach) Kernel Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.003-6%pads)
Prunus Persica (Peach) Kernel Oil Face and neck creams, lotions, and powders 0.2-0.4%
Prunus Persica (Peach) Kernel Oil Body and hand creams, lotions, and powders 0.8-3%
Prunus Persica (Peach) Kernel Oil Moisturizing creams, lotions and powders 0.08%
Prunus Persica (Peach) Kernel Oil Night creams, lotions and powders 0.08%
Prunus Persica (Peach) Kernel Oil Other suntan preparations 0.05%
Ribes Nigrum (Black Currant) Seed Oil Eye lotion 0.08%
Ribes Nigrum (Black Currant) Seed Oil Lipstick 0.03-0.1%
Ribes Nigrum (Black Currant) Seed Oil Nail creams and lotions 0.2%
Ribes Nigrum (Black Currant) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.05%pads)
Ribes Nigrum (Black Currant) Seed Oil Body and hand creams, lotions, and powders 0.01%.
Ribes Nigrum (Black Currant) Seed Oil Moisturizing creams, lotions and powders 0.1-0.3%
Ribes Nigrum (Black Currant) Seed Oil Night creams, lotions and powders 0.1%
Ribes Nigrum (Black Currant) Seed Oil Other skin care preparations 0.000001%
Rubus Idaeus (Raspberry) Seed Oil Face and neck creams, lotions, and powders 5%
Rubus Idaeus (Raspberry) Seed Oil Night creams, lotions and powders 0.1%
Sclerocarya Birrea Seed Oil Hair conditioners 1%
Sclerocarya Birrea Seed Oil Shampoos (noncoloring) 1%
Sclerocarya Birrea Seed Oil Body and hand creams, lotions and powders 1%
Sclerocarya Birrea Seed Oil Other skin care preparations 1%
Silybum Marianum Seed Oil Foundations [ 0.5%
Solanum Lycopersicum (Tomato) Fruit Eye shadow 0.0 1%Oil
Solanum Lycopersicum (Tomato) Fruit Blushers (all types) 0.0 1%Oil
Solanum Lycopersicum (Tomato) Fruit Face powders 0.05%Oil
Solanum Lycopersicum (Tomato) Fruit Lipstick 0.00 1%Oil
Solanum Lycopersicum (Tomato) Fruit Other skin care preparations 1%Oil
Theobroma Cacao (Cocoa) Seed Butter Baby lotions, oils, powders and creams 0.0 1%
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Theobroma Cacao (Cocoa) Seed Butter Other baby products 0.0 1%
Theobroma Cacao (Cocoa) Seed Butter Bath oils, tablets and salts 0.1%
Theobroma Cacao (Cocoa) Seed Butter Other bath preparations 1%
Theobroma Cacao (Cocoa) Seed Butter Eyebrow pencil 0.02%
Theobroma Cacao (Cocoa) Seed Butter Eyeliner 0.02-9%
Theobroma Cacao (Cocoa) Seed Butter Eye lotion 0.9-4%
Theobroma Cacao (Cocoa) Seed Butter Mascara 0.0002%
Theobroma Cacao (Cocoa) Seed Butter Hair conditioners 1%
Theobroma Cacao (Cocoa) Seed Butter Hair straighteners 0.01%
Theobroma Cacao (Cocoa) Seed Butter Shampoos (noncoloring) 0.0 1-0.1%
Theobroma Cacao (Cocoa) Seed Butter Tonics, dressings and other hair grooming aids 0.1-2%
Theobroma Cacao (Cocoa) Seed Butter Hair dyes and colors (all types requiring caution statement 0.1%and patch test)
Theobroma Cacao (Cocoa) Seed Butter Blushers (all types) 0.4%
Theobroma Cacao (Cocoa) Seed Butter Foundations 0.2-2%
Theobroma Cacao (Cocoa) Seed Butter Lipstick 0.3-37%
Theobroma Cacao (Cocoa) Seed Butter Makeup bases 0.02%
Theobroma Cacao (Cocoa) Seed Butter Makeup fixatives 0.00004%
Theobroma Cacao (Cocoa) Seed Butter Other makeup preparations 9%
Theobroma Cacao (Cocoa) Seed Butter Cuticle softeners 0.1%
Theobroma Cacao (Cocoa) Seed Butter Nail creams and lotions 1%
Theobroma Cacao (Cocoa) Seed Butter Bath soaps and detergents 0.02-2%
Theobroma Cacao (Cocoa) Seed Butter Deodorants (underarm) 0.00 1-1%
Theobroma Cacao (Cocoa) Seed Butter Other personal cleanliness products 0.1%
Theobroma Cacao (Cocoa) Seed Butter Aftershave lotions 1%
Theobroma Cacao (Cocoa) Seed Butter Shaving (aerosol, brushless and lather) 0.0 1-0.1%
Theobroma Cacao (Cocoa) Seed Butter Skin cleansing (cold creams, cleansing lotions, liquids and 0.0001-1%pads)
Theobroma Cacao (Cocoa) Seed Butter Depilatories 0.05-1%
Theobroma Cacao (Cocoa) Seed Butter Face and neck creams, lotions and powders 0.08-3%
Theobroma Cacao (Cocoa) Seed Butter Body and hand creams, lotions and powders 0.000002-6%
Theobroma Cacao (Cocoa) Seed Butter Foot powders and sprays 0.4%
Theobroma Cacao (Cocoa) Seed Butter Moisturizing creams, lotions and powders 2%
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Theobroma Cacao (Cocoa) Seed Butter Night creams, lotions asd powders 2%
Theobroma Cacao (Cocoa) Seed Butter Other skin care preparations 0.1-25%
Theobroma Cacao (Cocoa) Seed Butter Suntan gels, creams and liquids 5%
Theobroma Cacao (Cocoa) Seed Butter Indoor tanning preparations 0.1-0.5%
Theobroma Cacao (Cocoa) Seed Butter Other suntan preparations 0.5%
Theobroma Grandiflorum Seed Butter Eyeliner 2%
Theobroma Grandiflorum Seed Butter Eye shadow 0.1%
Theobroma Grandiflorum Seed Butter Eye lotion 2%
Theobroma Grandiflorum Seed Butter Hair conditioners 0.001-1%
Theobroma Grandiflorum Seed Butter Shampoos (noncoloring) 0.001-0.1%
Theobroma Grandiflorum Seed Butter Tonics, dressings and other hair grooming aids 0.01%
Theobroma Grandiflorum Seed Butter Other hair preparations (noncoloring) 1%
Theobroma Grandiflorum Seed Butter Foundations 5%
Theobroma Grandiflorum Seed Butter Lipstick 7%
Theobroma Grandiflorum Seed Butter Bath soaps and detergents 0.1%
Theobroma Grandiflorum Seed Butter Deodorants (underarm) 0.1%
Theobroma Grandiflorum Seed Butter Other personal cleanliness products 0.05%
Theobroma Grandiflorum Seed Butter Aftershave lotions 0. t %
Theobroma Grandiflorum Seed Butter Shaving cream (aerosol, brushless and lather) 0.1%
Theobroma Grandiflorum Seed Butter Skin cleansing (cold creams, cleansing lotions, liquids and 0.003%pads)
Theobroma Grandiflorum Seed Butter Face and neck creams, lotions and powders 2-5%
Theobroma Grandiflorum Seed Butter Body and hand creams, lotions and powders 0.1-5%
Theobroma Grandiflorum Seed Butter Moisturizing creams, lotions and powders 0.1%
Theobroma Grandiflorum Seed Butter Night creams, lotions and powders 0.1-3%
Theobroma Grandiflorum Seed Butter Other skin care preparations 0.00005%
Vaccinium Macrocarpon (Cranberry) Seed Hair conditioners 0.1%Oil
Vaccinium Macrocarpon (Cranberry) Seed Shampoos (noncoloring) 0.0 1%Oil
Vaccinium Macrocarpon (Cranberry) Seed Tonics, dressings and other hair grooming aids 0.1%Oil
Vaccinium Macrocarpon (Cranberry) Seed Foundations 0.1%Oil
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Vaccinium Macrocarpon (Cranberry) Seed Lipstick 0.3%Oil
Vaccinium Macrocarpon (Cranberry) Seed Other makeup preparations 0.002%Oil
Vaccinium Macrocarpon (Cranberry) Seed Bath soaps and detergents 0.003-0.1%Oil
Vaccinium Macrocarpon (Cranberry) Seed Face and neck creams, lotions and powders 2%Oil
Vaccinium Macrocarpon (Cranberry) Seed Body and hand creams, lotions and powders 0.1%Oil
Vaccinium Macrocarpon (Cranberry) Seed Moisturizing creams, lotions and powders 0.1%Oil
Vaccinium Macrocarpon (Cranberry) Seed Night creams, lotions and powders 0.1%Oil
Vitis Vinifera (Grape) Seed Oil Bath oils, tablets and salts 0.1-0.5%
Vitis Vinifera (Grape) Seed Oil Bubble baths 2%
Vitis Vinifera (Grape) Seed Oil Other bath preparations 0.01%
Vitis Vinifera (Grape) Seed Oil Eye lotion 5%
Vitis Vinifera (Grape) Seed Oil Eye makeup remover 0.01%
Vitis Vinifera (Grape) Seed Oil Perfumes 1%
Vitis Vinifera (Grape) Seed Oil Other fragrance preparations 0.00 1-7%
Vitis Vinifera (Grape) Seed Oil Hair conditioners 0.01-0.3%
Vitis Vinifera (Grape) Seed Oil Shampoos (noncoloring) 0.05-0.1%
Vitis Vinifera (Grape) Seed Oil Tonics, dressings and other hair grooming aids 0.01-0.1%
Vitis Vinifera (Grape) Seed Oil Hair dyes and colors (all types requiring caution statement 43%and patch test)
Vitis Vinifera (Grape) Seed Oil Foundations 0.2%
Vitis Vinifera (Grape) Seed Oil Lipstick 0.03-7%
Vitis Vinifera (Grape) Seed Oil Cuticle softeners 35%
Vitis Vinifera (Grape) Seed Oil Nail creams and lotions 1%
Vitis Vinifera (Grape) Seed Oil Nail polish and enamel 0.00 1%
Vitis Vinifera (Grape) Seed Oil Bath soaps and detergents 0.0 1-7%
Vitis Vinifera (Grape) Seed Oil Deodorants (underarm) 0.00 1-0.2%
Vitis Vinifera (Grape) Seed Oil Other personal cleanliness products 0.001-1%
Vitis Vinifera (Grape) Seed Oil Aftershave lotions 0.1-1%
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Vitis Vinifera (Grape) Seed Oil Preshave lotions (all types) 16-39%
Vitis Vinifera (Grape) Seed Oil Shaving cream (aerosol, brushless and lather) 2%
Vitis Vinifera (Grape) Seed Oil Other shaving preparations 0.1%
Vitis Vinifera (Grape) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.004-20%pads)
Vitis Vinifera (Grape) Seed Oil Depilatories 0.5%
Vitis Vinifera (Grape) Seed Oil Face and neck creams, lotions and powders 0.1-8%
Vitis Vinifera (Grape) Seed Oil Body and hand creams, lotions and powders 0.0141%
Vitis Vinifera (Grape) Seed Oil Body and hand sprays 1%
Vitis Vinifera (Grape) Seed Oil Moisturizing creams, lotions and powders 0.0 1-5%
Vitis Vinifera (Grape) Seed Oil Night creams, lotions and powders 0.0 1-5%
Vitis Vinifera (Grape) Seed Oil Paste masks (mud packs) 0.01%
Vitis Vinifera (Grape) Seed Oil Other skin care preparations 0.01-13%
Vitis Vinifera (Grape) Seed Oil Indoor tanning preparations 0.00 1%
Vitis Vinifera (Grape) Seed Oil Other suntan preparations 15%
Hydrogenated Grapeseed Oil Other bath preparations 0.5%
Hydrogenated Grapeseed Oil Lipstick 0.5%
Hydrogenated Grapeseed Oil Cuticle softeners 0.3%
Ingredients included in the title of the table, out not found in the table were included in the survey, but no uses were reportedInformation collected in 2010Table prepared May 13, 2010
The following ingredients will be included in a later concentration of use survey: Camellia Japonica Seed Oil, Citrus Aurantifolia(Lime) Seed Oil Unsaponifiables, Persea Gratissima (Avocado) Oil, Hydrogenated Avocado Oil, Persea Gratissima (Avocado)Butter, Persea Gratissima (Avocado) Oil Unsaponifiables, Sodium Avocadoate, Triticum Vulgare (Wheat) Germ Oil,Hydrogenated Wheat Germ Oil, Hydrogenated Wheat Germ Oil Unsaponifiables, Triticum Aestivum (Wheat) Germ Oil, TriticumVulgare (Wheat) Germ Oil Unsaponifiables and Wheat Germ Acid.
Page 15 of 15
CIR Panel Book Page 119
Personal Care Products CouncilCommitted to Safety,
ua if y nnovaf ion
Memorandum
TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (CIR)
FROM: John Bailey, Ph.D.Industry Liaison to the CIR Expert Panel
DATE: July 12, 2010
SUBJECT: Concentration of Use Plant Oils May 2010 Use Survey
CIR Panel Book Page 120
Concentration of Use by FDA Product CategoryGossypium Herbaceum (Cotton) Seed Oil, Cottonseed Acid, Hydrogenated Cottonseed Oil, Elaeis Guinennsis
(Palm) Oil, Elaeis Guinennsis (Palm) Kernel Oil, Hydrogenated Palm Oil, Hydrogenated Palm Kernel Oil,Elaeis Guineensis (Palm) Butter, Elaeis Oleifera Kernel Oil, Elaeis (Palm) Oil, Hydrogenated Palm Acid,Palm Acid, Palm Kernel Acid, Potassium Palmate, Potassium Hydrogenated Palmate, Potassium PalmKernelate, Sodium Hydrogenated Palmate, Sodium Palmate, Sodium Palm Kernelate, HydrogenatedSafflower Seed Oil, Potassium Safflowerate, Safflower Acid, Sodium Safflowerate, Sesamum Indicum
(Sesame) Seed Butter, Persea Gratissima (Avocado) Oil, Hydrogenated Avocado Oil, Persea Gratissima(Avocado) Butter, Persea Gratissima (Avocado) Oil Unsaponifiables, Sodium Avocadoate, Oryza Sativa
(Rice) Bran Oil, Oryza Sativa (Rice) Germ Oil, Rice Bran Acid, Hydrogenated Rice Bran Oil, Oryza Sativa(Rice) Seed Oil, Triticum Vulgare (Wheat) Germ Oil, Triticum Vulgare (Wheat) Germ Oil Unsaponifiables,
Hydrogenated Wheat Germ Oil, Hydrogenated Wheat Germ Oil Unsaponifiables, Triticum Aestivum(Wheat) Germ Oil, Wheat Germ Acid, Camellia Japonica Seed Oil, Citrus Aurantifolia (Lime) Seed Oil
Unsaponifiables
Ingredient Product Category Concentration ofUse
Gossypium Herbaceum (Cottonseed) Oil Eyeliner 0.1-11%
Gossypium Herbaceum (Cottonseed) Oil Eye shadow 0.1%
Gossypium Herbaceum (Cottonseed) Oil Eye lotion 0.5%
Gossypium Herbaceum (Cottonseed) Oil Foundations 0.5%
Gossypium Herbaceum (Cottonseed) Oil Lipstick 0.2-1%
Gossypium Herbaceum (Cottonseed) Oil Nail creams and lotions 30-32%
Gossypium Herbaceum (Cottonseed) Oil Other manicuring preparations 0.5%
Gossypium Herbaceum (Cottonseed) Oil Bath soaps and detergents 0.1%
Gossypium Herbaceum (Cottonseed) Oil Deodorants (underarm) 0.2%
Gossypium Herbaceum (Cottonseed) Oil Other personal cleanliness products 0.004-0.01%
Gossypium Herbaceum (Cottonseed) Oil Preshave lotions (all types) 29%
Gossypium Herbaceum (Cottonseed) Oil Shaving creams (aerosol, brushless and 1%lather)
Gossypium Herbaceum (Cottonseed) Oil Skin cleansing (cold creams, cleansing 0.5%lotions, liquids and pads)
Gossypium Herbaceum (Cottonseed) Oil Face and neck creams, lotions and powders 0.5%
Gossypium Herbaceum (Cottonseed) Oil Body and hand creams, lotions and powders 0.3-2%
Gossypium Herbaceum (Cottonseed) Oil Body and hand sprays 0.2%
Gossypium Herbaceum (Cottonseed) Oil Moisturizing creams, lotions and powders 0.08%
Gossypium Herbaceum (Cottonseed) Oil Night creams, lotions and powders 0.08-2%
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Gossypium Herbaceum (Cottonseed) Oil Other skin care preparations 5%
Hydrogenated Cottonseed Oil Eyebrow pencil 1 1-24%
Hydrogenated Cottonseed Oil Eyeliner 8-15%
Hydrogenated Cottonseed Oil Mascara 0.5%
Hydrogenated Cottonseed Oil Other eye makeup preparations 8%
Hydrogenated Cottonseed Oil Hair conditioners 0.0 1%
Hydrogenated Cottonseed Oil Shampoos (noncoloring) 0.01%
Hydrogenated Cottonseed Oil Tonics, dressings and other hair grooming 0.1%aids
Hydrogenated Cottonseed Oil Foundations 5%
Hydrogenated Cottonseed Oil Lipstick 8-12%
Hydrogenated Cottonseed Oil Other makeup preparations 0.002-1 1%
Hydrogenated Cottonseed Oil Face and neck creams, lotions and powders 0.005-5%
Hydrogenated Cottonseed Oil Other skin care preparations 0.00 1%
Elaeis Guineensis (Palm) Oil Eye lotion 0.04-2%
Elaeis Guineensis (Palm) Oil Hair conditioners 2%
Elaeis Guineensis (Palm) Oil Tonics, dressings and other hair grooming 13%aids
Elaeis Guineensis (Palm) Oil Other hair preparations (noncoloring) 34%
Elaeis Guineensis (Palm) Oil Foundations 5%
Elaeis Guineensis (Palm) Oil Lipstick 2%
Elaeis Guineensis (Palm) Oil Bath soaps and detergents 48%
Elaeis Guineensis (Palm) Oil Other personal cleanliness products 0.002%
Elaeis Guineensis (Palm) Oil Aftershave lotions 0.5%
Elaeis Guineensis (Palm) Oil Skin cleansing (cold creams, cleansing 0.002-8%lotions, liquids and pads)
Elaeis Guineensis (Palm) Oil Face and neck creams, lotions and powders 0.008-4%
Elaeis Guineensis (Palm) Oil Body and hand creams, lotions and powders 4-6%
Elaeis Guineensis (Palm) Oil Moisturizing creams, lotions and powders 0.4-3%
Elaeis Guineensis (Palm) Oil Night creams, lotions and powders 3-4%
Elaeis Guineensis (Palm) Oil Paste masks (mud packs) 4-5%
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Elaeis Guineensis (Palm) Oil Other skin care preparations 0.9-2%
Elaeis Guineensis (Palm) Kernel Oil Eye lotion 0.8%
Elaeis Guineensis (Palm) Kernel Oil Shampoos (noncoloring) 0.9-23%
Elaeis Guineensis (Palm) Kernel Oil Other manicuring preparations 3%
Elaeis Guineensis (Palm) Kernel Oil Bath soaps and detergents 0.05%
Elaeis Guineensis (Palm) Kernel Oil Shaving cream (aerosol, brushless and 0.05%lather)
Elaeis Guineensis (Palm) Kernel Oil Moisturizing creams, lotions and powders 0.8%
Elaeis Guineensis (Palm) Kernel Oil Other skin care preparations 2%
Hydrogenated Palm Oil Eyebrow pencil 3-5%
Hydrogenated Palm Oil Eyeliner 2-30%
Hydrogenated Palm Oil Eye lotion 0.9%
Hydrogenated Palm Oil Mascara 0.2%
Hydrogenated Palm Oil Colognes and toilet waters 1%
Hydrogenated Palm Oil Face powders 0.4%
Hydrogenated Palm Oil Foundations 8%
Hydrogenated Palm Oil Lipstick 2-30%
Hydrogenated Palm Oil Makeup bases 1%
Hydrogenated Palm Oil Makeup fixatives 0.5%
Hydrogenated Palm Oil Other makeup preparations 25%
Hydrogenated Palm Oil Bath soaps and detergents 2%
Hydrogenated Palm Oil Face and neck creams, lotions and powders 2%
Hydrogenated Palm Oil Body and hand creams, lotions and powders 10%
Hydrogenated Palm Oil Moisturizing creams, lotions and powders 3%
Hydrogenated Palm Oil Paste masks (mud packs) 2%
Hydrogenated Palm Oil Other skin care preparations 3%
Hydrogenated Palm Oil Suntan gels, creams and liquids 1%
Hydrogenated Palm Kernel Oil Eyebrow pencil 2%
Hydrogenated Palm Kernel Oil Eyeliner 7-10%
Hydrogenated Palm Kernel Oil Foundations 0.4%
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Hydrogenated Palm Kernel Oil Lipstick 3-13%
Hydrogenated Palm Kernel Oil Bath soaps and detergents 0.9-2%
Hydrogenated Palm Kernel Oil Face and neck creams, lotions and powders 1-5%
Hydrogenated Palm Kernel Oil Body and hand creams, lotions and powders 0.6-3%
Hydrogenated Palm Kernel Oil Moisturizing creams, lotions and powders 2%
Hydrogenated Palm Kernel Oil Night creams, lotions and powders 3%
Hydrogenated Palm Kernel Oil Paste masks (mud packs) 0.6-1%
Hydrogenated Palm Kernel Oil Suntan gels, creams and liquids 0.6%
Palm Acid Bath soaps and detergents 1-4%
Palm Acid Skin cleansing (cold creams, cleansing 17%lotions, liquids and pads)
Palm Kernel Acid Bath soaps and detergents 0.2-3%
Palm Kernel Acid Skin cleansing (cold creams, cleansing 12%lotions, liquids
Potassium Palmate I Bath soaps and detergents 0.3-3%
Potassium Palm Kernelate I Bath soaps and detergents 0.3-30%
Sodium Palmate Bath soaps and detergents 3-68%
Sodium Palmate Shaving soap (cakes, sticks, etc.) 63%
Sodium Palmate Skin cleansing (cold creams, cleansing 28%lotions, liquids and pads)
Sodium Palm Kernelate Bath soaps and detergents 16-44%
Sodium Palm Kernelate Shaving soaps (cakes, sticks, etc.) 15%
Sodium Palm Kernelate Skin cleansing (cold creams, cleansing 12%lotions, liquids and pads)
-
Persea Gratissima (Avocado) Oil Bath oils, tablets and salts 0.6-6%
Persea Gratissima (Avocado) Oil Eyeliner 0.1-1%
Persea Gratissima (Avocado) Oil Eye shadow 0.1%
Persea Gratissima (Avocado) Oil Eye lotion 0.05-2%
Persea Gratissima (Avocado) Oil Eye makeup remover 2%
Persea Gratissima (Avocado) Oil Mascara 0.2%
Persea Gratissima (Avocado) Oil Perfumes 8%
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Persea Gratissima (Avocado) Oil Powders (dusting and talcum) 02%
Persea Gratissima (Avocado) Oil Other fragrance preparations 1%
Persea Gratissima (Avocado) Oil Hair conditioners 0.0001-15%
Persea Gratissima (Avocado) Oil Hair sprays (aerosol fixatives) 0.05%
Persea Gratissima (Avocado) Oil Shampoos (noncoloring) 0.01-1%
Persea Gratissima (Avocado) Oil Tonics, dressings and other hair grooming 41%aids
Persea Gratissima (Avocado) Oil Hair dyes and colors (all types requiring 0.3%caution Statement and patch test)
Persea Gratissima (Avocado) Oil Hair rinses (coloring) 0.3%
Persea Gratissima (Avocado) Oil Blushers (all types) 0.2-0.5%
Persea Gratissima (Avocado) Oil Face powders 0.1-0.3%
Persea Gratissima (Avocado) Oil Foundations 0.0 1-3%
Persea Gratissima (Avocado) Oil Lipstick 0.05-26%
Persea Gratissima (Avocado) Oil Makeup bases 2%
Persea Gratissima (Avocado) Oil Other makeup preparations 0.1%
Persea Gratissima (Avocado) Oil Cuticle softeners 18-19%
Persea Gratissima (Avocado) Oil Nail creams and lotions 2-5%
Persea Gratissima (Avocado) Oil Nail polish and enamel 0.00 1%
Persea Gratissima (Avocado) Oil Other manicuring preparations 34%
Persea Gratissima (Avocado) Oil Bath soaps and detergents 0.02-0.5%
Persea Gratissima (Avocado) Oil Deodorants (underarm) 0.1%
Persea Gratissima (Avocado) Oil Other personal cleanliness products 1-3%
Persea Gratissima (Avocado) Oil Aftershave lotions 0.5%
Persea Gratissima (Avocado) Oil Preshave lotions (all types) 0.00 1%
Persea Gratissima (Avocado) Oil Shaving cream (aerosol. brushless and 0.05%lather)
Persea Gratissima (Avocado) Oil Other shaving preparations 0.8-2%
Persea Gratissima (Avocado) Oil Skin cleansing (cold creams, cleansing 0.003-3%lotions, liquids and pads)
Persea Gratissima (Avocado) Oil Depilatories 0. 1%
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Persea Gratissima (Avocado) Oil Face and neck creams, lotions and powders 0.01-98%
Persea Gratissima (Avocado) Oil Body and hand creams, lotions and powders 0.01-6%
Persea Gratissima (Avocado) Oil Foot powders and sprays 0.0 1%
Persea Gratissima (Avocado) Oil Moisturizing creams, lotions and powders 0.1-2%
Persea Gratissima (Avocado) Oil Night creams, lotions and powders 0.02-1%
Persea Gratissima (Avocado) Oil Paste masks (mud packs) 0.3-2%
Persea Gratissima (Avocado) Oil Other skin care preparations 0.1-31%
Persea Gratissima (Avocado) Oil Suntan gels, creams and liquids 0.02-2%
Persea Gratissima (Avocado) Oil Indoor tanning preparations 0.0005-0.5%
Hydrogenated Avocado Oil Other hair preparations (noncoloring) 0.5%
Persea Gratissima (Avocado) Oil Eye shadow 0.5%Unsaponifiables
Persea Gratissima (Avocado) Oil Tonics, dressings and other hair grooming 6%Unsaponifiables aids
Persea Gratissima (Avocado) Oil Lipstick 3%Unsaponifiables
Persea Gratissima (Avocado) Oil Skin cleansing (cold creams, cleansing 0.2%Unsaponifiables lotions , liquids and pads)
Oryza Sativa (Rice) Bran Oil Bath oils, tablets and salts 0.2%
Oryza Sativa (Rice) Bran Oil Eyeliner 0.8%
Oryza Sativa (Rice) Bran Oil Eye shadow 0.5%
Oryza Sativa (Rice) Bran Oil Eye lotion 0.5-0.6%
Oryza Sativa (Rice) Bran Oil Hair conditioners 0.2-0.3%
Oryza Sativa (Rice) Bran Oil Hair sprays (aerosol fixatives) 0.1%
Oryza Sativa (Rice) Bran Oil Shampoos (noncoloring) 0.005-0.3%
Oryza Sativa (Rice) Bran Oil Tonics, dressings and other hair grooming 0.02-0.5%aids
Oryza Sativa (Rice) Bran Oil Other hair preparations (noncoloring) 0.3%
Oryza Sativa (Rice) Bran Oil Hair rinses (coloring) 0.3%
Oryza Sativa (Rice) Bran Oil Face powders 0.3%
Oryza Sativa (Rice) Bran Oil Foundations 0.1-1%
Oryza Sativa (Rice) Bran Oil Lipstick 0.1-8%
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Oryza Sativa (Rice) Bran Oil Makeup bases 0.4%
Oryza Sativa (Rice) Bran Oil Nail creams and lotions 3-78%
Oryza Sativa (Rice) Bran Oil Nail polish and enamel 0.02%
Oryza Sativa (Rice) Bran Oil Other manicuring preparations 0.1%
Oryza Sativa (Rice) Bran Oil Bath soap and detergents 1%
Oryza Sativa (Rice) Bran Oil Deodorants (underarm) 0.5%
Oryza Sativa (Rice) Bran Oil Other personal cleanliness products 0.0006-6%
Oryza Sativa (Rice) Bran Oil Aftershave lotions 0.5%
Oryza Sativa (Rice) Bran Oil Preshave lotions (all types) 1%
Oryza Sativa (Rice) Bran Oil Skin cleansing (cold creams, cleansing 0.2-0.6%lotions, liquids and pads)
Oryza Sativa (Rice) Bran Oil Depilatories 0.5%
Oryza Sativa (Rice) Bran Oil Face and neck creams, lotions and powders 0.1-27%
Oryza Sativa (Rice) Bran Oil Body and hand creams, lotions and powders 0.5-5%
Oryza Sativa (Rice) Bran Oil Body and hand sprays 0.0003%
Oryza Sativa (Rice) Bran Oil Moisturizing creams, lotions and powders 8%
Oryza Sativa (Rice) Bran Oil Night creams, lotions and powders 4-5%
Oryza Sativa (Rice) Bran Oil Other skin care preparations 0.5-27%
Oryza Sativa (Rice) Germ Oil Bath oils, tablets and salts 3%
Oryza Sativa (Rice) Germ Oil Bubble baths 0.03%
Oryza Sativa (Rice) Germ Oil Eyebrow pencil 0.1%
Oryza Sativa (Rice) Germ Oil Eyeliner 0.1%
Oryza Sativa (Rice) Germ Oil Eye shadow 0.01%
Oryza Sativa (Rice) Germ Oil Eye makeup remover 0.01-0.1%
Oryza Sativa (Rice) Germ Oil Mascara 0.1-1%
Oryza Sativa (Rice) Germ Oil Blushers (all types) 0.1%
Oryza Sativa (Rice) Germ Oil Face powders 0.01%
Oryza Sativa (Rice) Germ Oil Foundations 0.1%
Oryza Sativa (Rice) Germ Oil Lipstick 0.1-3%
Oryza Sativa (Rice) Germ Oil Makeup bases 0.1%
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Oryza Sativa (Rice) Germ Oil Bath soaps and detergents 0.5%
Oryza Sativa (Rice) Germ Oil Deodorants (underarm) 0.003%
Oryza Sativa (Rice) Germ Oil Other personal cleanliness products 0.003-0.005%
Oryza Sativa (Rice) Germ Oil Skin cleansing (cold creams, cleansing 0.003-0.01%lotions, liquids and pads)
Oryza Sativa (Rice) Germ Oil Face and neck creams, lotions and powders 0.2-3%
Oryza Sativa (Rice) Germ Oil Body and hand creams, lotions and powders 0.02-2%
Oryza Sativa (Rice) Germ Oil Moisturizing creams, lotions and powders 0.01-0.1%
Oryza Sativa (Rice) Germ Oil Night creams, lotions and powders 0.08%
Oryza Sativa (Rice) Germ Oil Paste masks (mud packs) 0.0 1%
Oryza Sativa (Rice) Germ Oil Other skin care preparations 0.1%
Oryza Sativa (Rice) Germ Oil Suntan gels, creams and liquids 0.01%
Triticum Vulgare (Wheat) Germ Oil Bath oils, tablets and salts 0.5%
Triticum Vulgare (Wheat) Germ Oil Eye shadow 0.02%
Triticum Vulgare (Wheat) Germ Oil Eye lotion 0.1-0.5%
Triticum Vulgare (Wheat) Germ Oil Eye makeup remover 0.01%
Triticum Vulgare (Wheat) Germ Oil Mascara 0.05-0.1%
Triticum Vulgare (Wheat) Germ Oil Hair conditioners 0.00 1-0.5%
Triticum Vulgare (Wheat) Germ Oil Hair sprays (aerosol fixatives) 0.0001-00005%
Triticum Vulgare (Wheat) Germ Oil Shampoos (noncoloring) 0.00 1-0.5%
Triticum Vulgare (Wheat) Germ Oil Tonics, dressings and other hair grooming 0.00 1-0.5%aids
Triticum Vulgare (Wheat) Germ Oil Other hair preparations (noncoloring) 0.1%
Triticum Vulgare (Wheat) Germ Oil Hair dyes and colors (all types requiring 0.0 1-0.2%caution statement and patch test)
Triticum Vulgare (Wheat) Germ Oil Face powders 0.1%
Triticum Vulgare (Wheat) Germ Oil Foundations 0.00 1-2%
Triticum Vulgare (Wheat) Germ Oil Lipstick 0.3-5%
Triticum Vulgare (Wheat) Germ Oil Makeup bases 0.1%
Triticum Vulgare (Wheat) Germ Oil Cuticle softeners 1%
Triticum Vulgare (Wheat) Germ Oil Nail creams and lotions 3%
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Triticum Vulgare (Wheat) Germ Oil Other manicuring preparations 0.1-28%
Triticum Vulgare (Wheat) Germ Oil Bath soaps and detergents 0.0 1-0.5%
Triticum Vulgare (Wheat) Germ Oil Other personal cleanliness products 0.2%
Triticum Vulgare (Wheat) Germ Oil Skin cleansing (cold creams, cleansing 0.0 1-2%lotions , liquids and pads)
Triticum Vulgare (Wheat) Germ Oil Depilatories 0.6%
Triticum Vulgare (Wheat) Germ Oil Face and neck creams, lotions and powders 0.001-20%
Triticum Vulgare (Wheat) Germ Oil Body and hand creams, lotions and powders 0.3-1%
Triticum Vulgare (Wheat) Germ Oil Moisturizing creams, lotions and powders 0.5%
Triticum Vulgare (Wheat) Germ Oil Night creams, lotions and powders 0.08-0.5%
Triticum Vulgare (Wheat) Germ Oil Paste masks (mud packs) 2%
Triticum Vulgare (Wheat) Germ Oil Other skin care preparations 0.1-23%
Triticum Vulgare (Wheat) Germ Oil Suntan gels, creams and liquids 0.04%
Triticum Vulgare (Wheat) Germ Oil Indoor tanning preparations 0.0005%
Triticum Vulgare (Wheat) Germ Oil Face and neck creams, lotions and powders 0.2%Unsaponifiables
Triticum Aestivüm (Wheat) Germ Oil Hair conditioners <1%
Triticum Aestivum (Wheat) Germ Oil Hair straighteners <1%
Triticum Aestivum (Wheat) Germ Oil Moisturizing creams, lotions and powders <1%
Camellia Japonica Seed Oil Eye shadow 0.01%
Camellia Japonica Seed Oil Rinses (noncoloring) 0.1%
Camellia Japonica Seed Oil Blushers (all types) 0.01%
Camellia Japonica Seed Oil Lipstick 0.1%
Camellia Japonica Seed Oil Deodorants (underarm) 0.0 1%
Camellia Japonica Seed Oil Other personal cleanliness products 0.1%
Camellia Japonica Seed Oil Moisturizing creams, lotions and powders 0.2%*Ingredients included in the title of the table but not found in the table were included in the concentration of usesurvey, but no uses were reported.
Information collected in 2010Table prepared July 12, 2010
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Persona’ Care Products CouncilCommitted to Safety,Quality & Innovation
Memorandum
TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (CIR)
FROM: CIR Science and Support Committee
DATE: July2l,2010
SUBJECT: Concentration of Use Plant Oils Updated May 2010 Survey
1101 17th Street, N.W., Suite 300 Washington, D.C. 20036-4702 202.331.1770 I 202.331.1969 (fax) www.personalcarecouncil.org CIR Panel Book Page 130
Concentration of Use by FDA Product CategoryGossypium Herbaceum (Cotton) Seed Oil, Cottonseed Acid, Hydrogenated Cottonseed Oil, Elaeis Guinennsis
(Palm) Oil, Elaeis Guinennsis (Palm) Kernel Oil, Hydrogenated Palm Oil, Hydrogenated Palm Kernel Oil,Elaeis Guineensis (Palm) Butter, Elaeis Oleifera Kernel Oil, Elaeis (Palm) Oil, Hydrogenated Palm Acid,
Palm Acid, Palm Kernel Acid, Potassium Palmate, Potassium Hydrogenated Palmate, Potassium PalmKernelate, Sodium Hydrogenated Palmate, Sodium Palmate, Sodium Palm Kernelate, HydrogenatedSafflower Seed Oil, Potassium Safflowerate, Safflower Acid, Sodium Safflowerate, Sesamum Indicum
(Sesame) Seed Butter, Persea Gratissima (Avocado) Oil, Hydrogenated Avocado Oil, Persea Gratissima(Avocado) Butter, Persea Gratissima (Avocado) Oil Unsaponifiables, Sodium Avocadoate, Oryza Sativa
(Rice) Bran Oil, Oryza Sativa (Rice) Germ Oil, Rice Bran Acid, Hydrogenated Rice Bran Oil, Oryza Sativa(Rice) Seed Oil, Triticum Vulgare (Wheat) Germ Oil, Triticum Vulgare (Wheat) Germ Oil Unsaponiflables,
Hydrogenated Wheat Germ Oil, Hydrogenated Wheat Germ Oil Unsaponiflables, Triticum Aestivum(Wheat) Germ Oil, Wheat Germ Acid, Camellia Japonica Seed Oil, Citrus Aurantifolia (Lime) Seed Oil
Unsaponifiables
Ingredient Product Category Concentration ofUse
Gossypium Herbaceum (Cottonseed) Oil Eyeliner 0.1-11%
Gossypium Herbaceum (Cottonseed) Oil Eye shadow 0.1%
Gossypium Herbaceum (Cottonseed) Oil Eye lotion 0.5%
Gossypium Herbaceum (Cottonseed) Oil Foundations 0.5%
Gossypium Herbaceum (Cottonseed) Oil Lipstick 0.2-1%
Gossypium Herbaceum (Cottonseed) Oil Nail creams and lotions 30-32%
Gossypium Herbaceum (Cottonseed) Oil Other manicuring preparations 0.5%
Gossypium Herbaceum (Cottonseed) Oil Bath soaps and detergents 0.1%
Gossypium Herbaceum (Cottonseed) Oil Deodorants (underarm) 0.2%
Gossypium Herbaceum (Cottonseed) Oil Other personal cleanliness products 0.004-0.01%
Gossypium Herbaceum (Cottonseed) Oil Preshave lotions (all types) 29%
Gossypium Herbaceum (Cottonseed) Oil Shaving creams (aerosol, brushless and 1%lather)
Gossypium Herbaceum (Cottonseed) Oil Skin cleansing (cold creams, cleansing 0.5%lotions, liquids and pads)
Gossypium Herbaceum (Cottonseed) Oil Face and neck creams, lotions and powders 0.5%
Gossypium Herbaceum (Cottonseed) Oil Body and hand creams, lotions and powders 0.3-2%
Gossypium Herbaceum (Cottonseed) Oil Body and hand sprays 0.2%
Gossypium Herbaceum (Cottonseed) Oil Moisturizing creams, lotions and powders 0.08%
Gossypium Herbaceum (Cottonseed) Oil Night creams, lotions and powders 0.08-2%
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Gossypium Herbaceum (Cottonseed) Oil Other skin care preparations 5%
Hydrogenated Cottonseed Oil Eyebrow pencil 11-24%
Hydrogenated Cottonseed Oil Eyeliner 8-15%
Hydrogenated Cottonseed Oil Mascara 0.5%
Hydrogenated Cottonseed Oil Other eye makeup preparations 8%
Hydrogenated Cottonseed Oil Hair conditioners 0.01%
Hydrogenated Cottonseed Oil Shampoos (noncoloring) 0.01%
Hydrogenated Cottonseed Oil Tonics, dressings and other hair grooming 0.1%aids
Hydrogenated Cottonseed Oil Foundations 5%
Hydrogenated Cottonseed Oil Lipstick 8-12%
Hydrogenated Cottonseed Oil Other makeup preparations 0.002-11%
Hydrogenated Cottonseed Oil Face and neck creams, lotions and powders 0.005-5%
Hydrogenated Cottonseed Oil Other skin care preparations 0.00 1%
Elaeis Guineensis (Palm) Oil Eye lotion 0.04-2%
Elaeis Guineensis (Palm) Oil Hair conditioners 2%
Elaeis Guineensis (Palm) Oil Tonics, dressings and other hair grooming 13%aids
Elaeis Guineensis (Palm) Oil Other hair preparations (noncoloring) 34%
Elaeis Guineensis (Palm) Oil Foundations 5%
Elaeis Guineensis (Palm) Oil Lipstick 2%
Elaeis Guineensis (Palm) Oil Bath soaps and detergents 48%
Elaeis Guineensis (Palm) Oil Other personal cleanliness products 0.002%
Elaeis Guineensis (Palm) Oil Aftershave lotions 0.5%
Elaeis Guineensis (Palm) Oil Skin cleansing (cold creams, cleansing 0.002-8%lotions, liquids and pads)
Elaeis Guineensis (Palm) Oil Face and neck creams, lotions and powders 0.008-4%
Elaeis Guineensis (Palm) Oil Body and hand creams, lotions and powders 4-6%
Elaeis Guineensis (Palm) Oil Moisturizing creams, lotions and powders 0.4-3%
Elaeis Guineensis (Palm) Oil Night creams, lotions and powders 3-4%
Elaeis Guineensis (Palm) Oil Paste masks (mud packs) 4-5%
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Elaeis Guineensis (Palm) Oil Other skin care preparations 0.9-2%
Elaeis Guineensis (Palm) Kernel Oil Eye lotion 0.8%
Elaeis Guineensis (Palm) Kernel Oil Shampoos (noncoloring) 0.9-23%
Elaeis Guineensis (Palm) Kernel Oil Other manicuring preparations 3%
Elaeis Guineensis (Palm) Kernel Oil Bath soaps and detergents 0.05%
Elaeis Guineensis (Palm) Kernel Oil Shaving cream (aerosol, brushless and 0.05%lather)
Elaeis Guineensis (Palm) Kernel Oil Moisturizing creams, lotions and powders 0.8%
Elaeis Guineensis (Palm) Kernel Oil Other skin care preparations 2%
Hydrogenated Palm Oil Eyebrow pencil 3-5%
Hydrogenated Palm Oil Eyeliner 2-30%
Hydrogenated Palm Oil Eye lotion 0.9%
Hydrogenated Palm Oil Mascara 0.2%
Hydrogenated Palm Oil Colognes and toilet waters 1%
Hydrogenated Palm Oil Face powders 0.4%
Hydrogenated Palm Oil Foundations 8%
Hydrogenated Palm Oil Lipstick 2-30%
Hydrogenated Palm Oil Makeup bases 1%
Hydrogenated Palm Oil Makeup fixatives 0.5%
Hydrogenated Palm Oil Other makeup preparations 25%
Hydrogenated Palm Oil Bath soaps and detergents 2%
Hydrogenated Palm Oil Face and neck creams, lotions and powders 2%
Hydrogenated Palm Oil Body and hand creams, lotions and powders 10%
Hydrogenated Palm Oil Moisturizing creams, lotions and powders 3%
Hydrogenated Palm Oil Paste masks (mud packs) 2%
Hydrogenated Palm Oil Other skin care preparations 3%
Hydrogenated Palm Oil Suntan gels, creams and liquids 1%
Hydrogenated Palm Kernel Oil Eyebrow pencil 2%
Hydrogenated Palm Kernel Oil Eyeliner 7-10%
Hydrogenated Palm Kernel Oil Foundations 0.4%
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Hydrogenated Palm Kernel Oil Lipstick 3-13%
Hydrogenated Palm Kernel Oil Bath soaps and detergents 0.9-2%
Hydrogenated Palm Kernel Oil Face and neck creams, lotions and powders 1-5%
Hydrogenated Palm Kernel Oil Body and hand creams, lotions and powders 0.6-3%
Hydrogenated Palm Kernel Oil Moisturizing creams, lotions and powders 2%
Hydrogenated Palm Kernel Oil Night creams, lotions and powders 3%
Hydrogenated Palm Kernel Oil Paste masks (mud packs) 0.6-1%
Hydrogenated Palm Kernel Oil Suntan gels, creams and liquids 0.6%
Palm Acid Bath soaps and detergents 1-4%
Palm Acid Skin cleansing (cold creams, cleansing 17%lotions, liquids and pads)
Palm Kernel Acid Bath soaps and detergents 0.2-3%
Palm Kernel Acid Skin cleansing (cold creams, cleansing 12%lotions, liquids
Potassium Palmate Bath soaps and detergents 0.3-3%
Potassium Palm Kernelate Bath soaps and detergents 0.3-30%
Sodium Palmate Bath soaps and detergents 3-68%
Sodium Palmate Shaving soap (cakes, sticks, etc.) 63%
Sodium Palmate Skin cleansing (cold creams, cleansing 28%lotions, liquids and pads)
Sodium Palm Kernelate Bath soaps and detergents 16-44%
Sodium Palm Kernelate Shaving soaps (cakes, sticks, etc.) 15%
Sodium Palm Kernelate Skin cleansing (cold creams, cleansing 12%lotions, liquids and pads)
Persea Gratissima (Avocado) Oil Bath oils, tablets and salts 0.6-6%
Persea Gratissima (Avocado) Oil Eyeliner 0.1-1%
Persea Gratissima (Avocado) Oil Eye shadow 0.1%
Persea Gratissima (Avocado) Oil Eye lotion 0.05-2%
Persea Gratissima (Avocado) Oil Eye makeup remover 2%
Persea Gratissima (Avocado) Oil Mascara 0.2%
Persea Gratissima (Avocado) Oil Perfumes 8%
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Persea Gratissima (Avocado) Oil Powders (dusting and talcum) 0.2%
Persea Gratissima (Avocado) Oil Other fragrance preparations 1%
Persea Gratissima (Avocado) Oil Hair conditioners 0.0001-15%
Persea Gratissima (Avocado) Oil Hair sprays (aerosol fixatives) 0.05%
Persea Gratissima (Avocado) Oil Shampoos (noncoloring) 0.01-1%
Persea Gratissima (Avocado) Oil Tonics, dressings and other hair grooming 41%aids
Persea Gratissima (Avocado) Oil Hair dyes and colors (all types requiring 0.3%caution statement and patch test)
Persea Gratissima (Avocado) Oil Hair rinses (coloring) 0.3%
Persea Gratissima (Avocado) Oil Blushers (all types) 0.2-0.5%
Persea Gratissima (Avocado) Oil Face powders 0.1-0.3%
Persea Gratissima (Avocado) Oil Foundations 0.01-3%
Persea Gratissima (Avocado) Oil Lipstick 0.05-26%
Persea Gratissima (Avocado) Oil Makeup bases 2%
Persea Gratissima (Avocado) Oil Other makeup preparations 0.1%
Persea Gratissima (Avocado) Oil Cuticle softeners 18-19%
Persea Gratissima (Avocado) Oil Nail creams and lotions 2-5%
Persea Gratissima (Avocado) Oil Nail polish and enamel 0.00 1%
Persea Gratissima (Avocado) Oil Other manicuring preparations 34%
Persea Gratissima (Avocado) Oil Bath soaps and detergents 0.02-0.5%
Persea Gratissima (Avocado) Oil Deodorants (underarm) 0.1%
Persea Gratissima (Avocado) Oil Other personal cleanliness products 1-3%
Persea Gratissima (Avocado) Oil Aftershave lotions 0.5%
Persea Gratissima (Avocado) Oil Preshave lotions (all types) 0.00 1%
Persea Gratissima (Avocado) Oil Shaving cream (aerosol, brushless and 0.05%lather)
Persea Gratissima (Avocado) Oil Other shaving preparations 0.8-2%
Persea Gratissima (Avocado) Oil Skin cleansing (cold creams, cleansing 0.003-3%lotions, liquids and pads)
Persea Gratissima (Avocado) Oil Depilatories 0.1%
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Persea Gratissima (Avocado) Oil Face and neck creams, lotions and powders 0.01-98%
Persea Gratissima (Avocado) Oil Body and hand creams, lotions and powders 0.01-6%
Persea Gratissima (Avocado) Oil Foot powders and sprays 0.0 1%
Persea Gratissima (Avocado) Oil Moisturizing creams, lotions and powders 0.1-2%
Persea Gratissima (Avocado) Oil Night creams, lotions and powders 0.02-1%
Persea Gratissima (Avocado) Oil Paste masks (mud packs) 0.3-2%
Persea Gratissima (Avocado) Oil Other skin care preparations 0.1-31%
Persea Gratissima (Avocado) Oil Suntan gels, creams and liquids 0.02-2%
Persea Gratissima (Avocado) Oil Indoor tanning preparations 0.0005-0.5%
Hydrogenated Avocado Oil Other hair preparations (noncoloring) 0.5%
Persea Gratissima (Avocado) Oil Eye shadow 0.5%Unsaponifiables
Persea Gratissima (Avocado) Oil Tonics, dressings and other hair grooming 6%Unsaponifiables aids
Persea Gratissima (Avocado) Oil Lipstick 3%Unsaponifiables
Persea Gratissima (Avocado) Oil Skin cleansing (cold creams, cleansing 0.2%Unsaponifiables lotions , liquids and pads)
Oryza Sativa (Rice) Bran Oil Bath oils, tablets and salts 0.2%
Oryza Sativa (Rice) Bran Oil Eyeliner 0.8%
Oryza Sativa (Rice) Bran Oil Eye shadow 0.5%
Oryza Sativa (Rice) Bran Oil Eye lotion 0.5-0.6%
Oryza Sativa (Rice) Bran Oil Hair conditioners 0.2-0.3%
Oryza Sativa (Rice) Bran Oil Hair sprays (aerosol fixatives) 0.1%
Oryza Sativa (Rice) Bran Oil Shampoos (noncoloring) 0.005-0.3%
Oryza Sativa (Rice) Bran Oil Tonics, dressings and other hair grooming 0.02-0.5%aids
Oryza Sativa (Rice) Bran Oil Other hair preparations (noncoloring) 0.3%
Oryza Sativa (Rice) Bran Oil Hair rinses (coloring) 0.3%
Oryza Sativa (Rice) Bran Oil Face powders 0.3%
Oryza Sativa (Rice) Bran Oil Foundations 0.1-1%
Oryza Sativa (Rice) Bran Oil Lipstick 0.1-8%
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Oryza Sativa (Rice) Bran Oil Makeup bases 0.4%
Oryza Sativa (Rice) Bran Oil Nail creams and lotions 3-78%
Oryza Sativa (Rice) Bran Oil Nail polish and enamel 0.02%
Oryza Sativa (Rice) Bran Oil Other manicuring preparations 0.1%
Oryza Sativa (Rice) Bran Oil Bath soap and detergents 1%
Oryza Sativa (Rice) Bran Oil Deodorants (underarm) 0.5%
Oryza Sativa (Rice) Bran Oil Other personal cleanliness products 0.0006-6%
Oryza Sativa (Rice) Bran Oil Aftershave lotions 0.5%
Oryza Sativa (Rice) Bran Oil Preshave lotions (all types) 1%
Oryza Sativa (Rice) Bran Oil Skin cleansing (cold creams, cleansing 0.2-0.6%lotions, liquids and pads)
Oryza Sativa (Rice) Bran Oil Depilatories 0.5%
Oryza Sativa (Rice) Bran Oil Face and neck creams, lotions and powders 0.1-27%
Oryza Sativa (Rice) Bran Oil Body and hand creams, lotions and powders 0.5-5%
Oryza Sativa (Rice) Bran Oil Body and hand sprays 0.0003%
Oryza Sativa (Rice) Bran Oil Moisturizing creams, lotions and powders 8%
Oryza Sativa (Rice) Bran Oil Night creams, lotions and powders 4-5%
Oryza Sativa (Rice) Bran Oil Other skin care preparations 0.5-27%
Oryza Sativa (Rice) Germ Oil Bath oils, tablets and salts 3%
Oryza Sativa (Rice) Germ Oil Bubble baths 0.03%
Oryza Sativa (Rice) Germ Oil Eyebrow pencil 0.1%
Oryza Sativa (Rice) Germ Oil Eyeliner 0.1%
Oryza Sativa (Rice) Germ Oil Eye shadow 0.0 1%
Oryza Sativa (Rice) Germ Oil Eye makeup remover 0.01-0.1%
Oryza Sativa (Rice) Germ Oil Mascara 0.1-1%
Oryza Sativa (Rice) Germ Oil Blushers (all types) 0.1%
Oryza Sativa (Rice) Germ Oil Face powders 0.0 1%
Oryza Sativa (Rice) Germ Oil Foundations 0.1%
Oryza Sativa (Rice) Germ Oil Lipstick 0.1-3%
Oryza Sativa (Rice) Germ Oil Makeup bases 0.1%
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Oryza Sativa (Rice) Germ Oil Bath soaps and detergents 05%
Oryza Saliva (Rice) Germ Oil Deodorants (underarm) 0.003%
Oryza Sativa (Rice) Germ Oil Other personal cleanliness products 0.003-0.005%
Oryza Sativa (Rice) Germ Oil Skin cleansing (cold creams, cleansing 0.003-0.01%lotions, liquids and pads)
Oryza Sativa (Rice) Germ Oil Face and neck creams, lotions and powders 0.2-3%
Oryza Sativa (Rice) Germ Oil Body and hand creams, lotions and powders 0.02-2%
Oryza Sativa (Rice) Germ Oil Moisturizing creams, lotions and powders 0.01-0.1%
Oryza Sativa (Rice) Germ Oil Night creams, lotions and powders 0.08%
Oryza Saliva (Rice) Germ Oil Paste masks (mud packs) 0.01%
Oryza Sativa (Rice) Germ Oil Other skin care preparations 0.1%
Oryza Sativa (Rice) Germ Oil Suntan gels, creams and liquids 0.01%
Triticum Vulgare (Wheat) Germ Oil Bath oils, tablets and salts 0.5%
Triticum Vulgare (Wheat) Germ Oil Eye shadow 0.02%
Triticum Vulgare (Wheat) Germ Oil Eye lotion 0.1-0.5%
Triticum Vulgare (Wheat) Germ Oil Eye makeup remover 0.0 1%
Triticum Vulgare (Wheat) Germ Oil Mascara 0.05-0.1%
Triticum Vulgare (Wheat) Germ Oil Hair conditioners 0.00 1-0.5%
Triticum Vulgare (Wheat) Germ Oil Hair sprays (aerosol fixatives) 0.0001-00005%
Triticum Vulgare (Wheat) Germ Oil Hair straighteners <1%
Triticum Vulgare (Wheat) Germ Oil Shampoos (noncoloring) 0.00 1-0.5%
Triticum Vulgare (Wheat) Germ Oil Tonics, dressings and other hair grooming 0.00 1-0.5%aids
Triticum Vulgare (Wheat) Germ Oil Other hair preparations (noncoloring) 0.1%
Triticum Vulgare (Wheat) Germ Oil Hair dyes and colors (all types requiring 0.0 1-0.2%caution statement and patch test)
Triticum Vulgare (Wheat) Germ Oil Face powders 0.1%
Triticum Vulgare (Wheat) Germ Oil Foundations 0.001-2%
Triticum Vulgare (Wheat) Germ Oil Lipstick 0.3-5%
Triticum Vulgare (Wheat) Germ Oil Makeup bases 0.1%
Triticum Vulgare (Wheat) Germ Oil Cuticle softeners 1%
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Triticum Vulgare (Wheat) Germ Oil Nail creams and lotions 3%
Triticum Vulgare (Wheat) Germ Oil Other manicuring preparations 0.1-28%
Triticum Vulgare (Wheat) Germ Oil Bath soaps and detergents 0.01-0.5%
Triticum Vulgare (Wheat) Germ Oil Other personal cleanliness products 0.2%
Triticum Vulgare (Wheat) Germ Oil Skin cleansing (cold creams, cleansing 0.0 1-2%lotions , liquids and pads)
Triticum Vulgare (Wheat) Germ Oil Depilatories 0.6%
Triticum Vulgare (Wheat) Germ Oil Face and neck creams, lotions and powders 0.00 1-20%
Triticum Vulgare (Wheat) Germ Oil Body and hand creams, lotions and powders 0.3-1%
Triticum Vulgare (Wheat) Germ Oil Moisturizing creams, lotions and powders 0.5-1%
Triticum Vulgare (Wheat) Germ Oil Night creams, lotions and powders 0.08-0.5%
Triticum Vulgare (Wheat) Germ Oil Paste masks (mud packs) 2%
Triticum Vulgare (Wheat) Germ Oil Other skin care preparations 0.1-23%
Triticum Vulgare (Wheat) Germ Oil Suntan gels, creams and liquids 0.04%
Triticum Vulgare (Wheat) Germ Oil Indoor tanning preparations 0.0005%
Triticum Vulgare (Wheat) Germ Oil Face and neck creams, lotions and powders 0.2%Unsaponifiables
Camellia Japonica Seed Oil Eye shadow 0.0 1%
Camellia Japonica Seed Oil Rinses (noncoloring) 0.1%
Camellia Japonica Seed Oil Blushers (all types) 0.01%
Camellia Japonica Seed Oil Lipstick 0.1%
Camellia Japonica Seed Oil Deodorants (underarm) 0.0 1%
Camellia Japonica Seed Oil Other personal cleanliness products 0.1%
Camellia Japonica Seed Oil Moisturizing creams, lotions and powders 0.2%*Ingredients included in the title of the table but not found in the table were included in the concentration of usesurvey, but no uses were reported.
Information collected in 2010Table prepared July 12, 2010
Updated July 21, 2010 (Triticum Aestivum removed)
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Personal Care Products CouncilCommitted to Safety,Quality & Innovation
Memorandum
TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDiENT REVIEW (Cifi)
FROM: Plant Oil Subcommittee of the Cifi Science and Support Committee
DATE: May 11, 2010
SUBJECT: Comments on the Scientific Literature Review on Vegetable Oil and Related EdibleOils and Derivatives as Used in Cosmetics
A Subcommittee of the CW Science and Support Committee (CIR SSC) reviewed the ScientificLiterature Review (SLR) on Vegetable Oil and Related Edible Oils and Derivatives as Used inCosmetics. The subcommittee is concerned that the SLR contains incorrect information aboutthe chemistry of plant oils, and that the composition information on the oils is still veryincomplete. The subcommittee recommends that the Vegetable Oil and Related Edible Oilsand Derivatives report be revised based on these comments before the CW Expert Panel isgiven the opportunity to review the report. This delay will also allow industry to work onidentifying additional dermal safety data on the ingredients in the report before the report isprovided to the Cifi Expert Panel
In the introduction, please provide a rational as to why the ingredients listed in Table 1 are included inthe report. Please consider including only triglyceride oils (oils, butters and hydrogenated oils)in this report, removing the fatty acids, salts of fatty acids and unsaponifiables. If theunsaponifiable ingredients are left in the report, please provide a rational as to why it isappropriate to include these ingredients in the report, as they generally are neither triglyceridesnor fatty acids.
The Dictionary has misclassified at least three of the ingredients listed in Table 1. AngelicaArchangelica Seed Oil, Apium Graveolens (Celery) Seed Oil, and Daucus Carota Sativa(Carrot) Seed Oil are all essential oils rather than in the chemical class fats and oils. Thechemical class for these ingredients listed in the Dictionary has now been changed to essentialoil. These three ingredients need to be removed from the report. Food Chemical Codex saysthese ingredients are obtained by steam distillation. This is how essential oils are obtained, nottriglyceride oils.
Please consider moving Sclerocarya Birrea Seed Oil, Mangifera Indica (Mango) Seed Oil andMangifera Indica (Mango) Seed Butter to the nut oil report. These two species are in the familyAnacardiaceae, along with other nuts such as cashews and pistachios.
If composition information on an oil cannot be identified in either published or unpublished reports,please consider removing the oil from the report.
1101 17th Street, N.W., Suite 300 Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org CIR Panel Book Page 140
Title - The title of the report should be changed. Edible is not an appropriate descriptor for all of theseoils. Vegetable oils may be a better term to describe them. If the fatty acids andunsaponifiables are left in the report these classes of ingredients should be specificallymentioned in the title.
p.1 - Although common names may be easier, the full INCI names including genus species nameshould be used to avoid confusion (see blackberry seed oil example below).
p.1 - If the fatty acids are left in the report, it should be made clear that “acid” refers to “fatty acid”.p.1 - It is not correct to state the oils are “mixtures of fatty acids”. The oils are mixtures of glyceryl
esters of fatty acids.p.1, 14, Table 2 - It should also be noted that the glyceryl triesters have been reviewed by Cifi and
found safe as used (report published in 2001).p.1 - The Chemistry section needs to be rewritten. These oils are not “a varying assortment of fatty
acids.” As indicated in the fats and oils chemical class definition in the Dictionary, “Fats andOils, as a group, are the glyceryl esters of Fatty Acids (triglycerides)” - a general structure asshown in the Dictionary definition of the fats and oils chemical class would also be helpful.The Chemistry section should note how the hydrogenated oil differs from the oil(hydrogenation reduces or eliminates unsaturation) and define butter (“solid triglyceridewithout any modification”). If the fatty acid and unsaponifiable ingredients are left in thereport, these terms should also be defined. The Dictionary says “unsaponifiables refers to lipidcomponents of natural Fats and Oils which are not hydrolyzed and remain soluble in lipidsolvents after alkaline hydrolysis”. More information about oil chemistry basics can be foundin AAK AarhusKarlshamn Handbook Vegetable Fats and Oils athttp://www.annaochanna.se/pdf/Vegetabilisk%20Handbok.pdf (this is large file that may take along time to open).
p.1, 15-18, Table 3 - Please provide a reason as to why fatty acid composition for some oils areincluded in Table 3 but others are not included. For example the fatty acid composition ofOenothera Biennis (Evening Primrose) Oil is readily available on the internet, e.g.,http://www.vitaplant.ch/plant-oils.pdf and is also found in the PDR for Herbal Medicines (acopy can be found in CJE’s office). Why is the composition of Oenothera Biennis (EveningPrimrose) Oil missing from Table 3? If it has not been done already, please search theAGRICOLA - AGRICultural On Line Access http://www.nal.usda.gov/ag98/ database whichmay have additional information about composition of the plant oils included in this report.Were there criteria for the types of references that were included for composition informationcompared to the types of references that were not included? If only specific references wereconsidered acceptable, the acceptance criteria should be stated.
p.1 - It should be noted that Table 4 includes Food Chemical Codex specifications for oils whereavailable.
p.1 - Please be consistent when talking about vitamin E. In the last paragraph, both vitamin E and -
tocopherol are used.p.2 - As nut oils are not included in this report, “nut” should be removed from the first paragraph of the
Processing section.
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p.2, 22-28, Table 5 - The members of the Cifi Expert Panel are accustomed to seeing the cosmetic useinformation by FDA product category. It would be helpful if the CIR Expert Panel memberswere provided with an explanation about which FDA categories fit in each of the categoriespresented in Table 5. For example, From the categories provided in Table 5, it is not clearwhich category includes the FDA bath product categories. Bath products are highly dilutedbefore use. Including them with rinse-off products would be misleading, as the concentrationsof some ingredients in bath products may be higher than in rinse-off products, although actualexposure concentrations will be lower. As FDA uses the term “baby” please continue to use“baby” rather than “infant” - the use of “infant” suggests you mean something different thanwhat is meant by the FDA product category terms. Use information as provided in Table 5 isnot sufficient to complete as risk assessment. A specific product category is needed to estimateexposure.
p.3 - In the second paragraph of this page, please change “particle diameters” to “aerodynamicdiameters” or “da” as used in the previous paragraph.
p.3 - Please add the concentrations of Elaeis Guineensis (Palm) Oil that were practically non- tominimally irritating to rabbit skin. What concentration was non-allergenic in a maximizationstudy? What protocol was used for the in vitro phototoxicity study?
p.4 - In the Olea Europaea (Olive) Fruit Oil section, it would be helpful to note that acetone/olive oil isthe recommended vehicle in murine local lymph node assays (seehttp://iccvam.niehs.nih.gov/docs/immunotox docs/llna/LLNAProt .pdf).
p.4 - What protocol was used in the guinea pig sensitization study by Grover (1962) (reference 20) (itshould be briefly mentioned each time this study is discussed)? Was the composition of the 10-year old oil olive oil measured?
p.4 - What concentrations of Oryza Sativa (Rice) Bran Oil were not irritating or sensitizing to animals?p.4 - What were the concentrations of Triticum Vulgare (Wheat) Germ Oil tested in formulations?p.5 - Please provide a reference that indicates that limonene is a main component of citrus seed oils.
Limonene is a major component of citrus essential oils (from the peel and fruit), but those oilsare not the subject of this report. If the citrus seed oils are not triglycerides they should beremoved from the report. Please see the following reference athttp://www.fshs .org/Proceedings/Password%20Protectedl1963 %2OVol. %2076/249-253 %20(HENDRICKSON).pdf for information on the composition of lemon seed oil.Hendrickson H, Kesterson. 1963. Florida lemon seed oil. Florida Agricultural Experimental
Station Journal Series No. 1726. Florida State Horticultural Society.The following references may also be helpful in determining the composition of the citrus seedoils.Ranganna S, Govindarajan VS, Ramana Ky. 1983. Citrus Fruits Part II Chemistry, technology
and quality evaluation Part A. Chemistry Crit Rev Food Sci Nutr 18(4): 3 13-386Part B. Technology Crit Rev Food Sci Nutr 19(1) 1-98.
p.6 - What concentrations of Oryza Sativa (Rice) Bran Oil and Oryza Sativa (Rice) Germ Oil werenon- to minimally irritating to rabbit eyes? As two oils are mentioned, they should both be inthe subheading.
p.6 - What concentration of Triticum Vulgare (Wheat) Germ Oil was not an ocular irritant?
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p.6-7 - IARC states that glycidol is not known to occur as a natural product. IARC did not assess“glycidol fatty esters in refined vegetable oils”, they assessed glycidyl stearate and glycidyloleate and put them in Group 3. If the Cifi Expert Panel determines that the carcinogenicity ofglycidol is important to assessing the safety of the plant oils, tL NTP study (found athttp://ntp.ni ehs.ni h. gov/ntp/htdocs/LT rpts/tr3 74.pdf) should be cited.
p.6-7 - The English summary of the BdR report is athttp://www.bfr.bund.de/cm1245/initial evaluation of the assessment of levels of glycidol fatty acid esters.pdf. They also state “At the present time, the detection of glycidol fatty acidesters in refined vegetable fats has no impact on the fundamental statements on the riskassessment of 3-MCPD fatty acid esters which also occur in these fats.’
p.7 - If “the conversion of glycidol to 3-chloropropanediol was presented as an artifact of the analyticalmethod”, why is this information in the report? Please identify the “crude oil” discussed in thepresentation by Weisshour.
p.7 - If the CIR Expert Panel believes that carcinogenicity is an issue for the oils reviewed in the report,literature searches on carcinogenicity and each oil need to be completed and studies on thecarcinogenicity of the oils need to be added to the report.
p.7 - Aflatoxins are a toxicity issue and not an allergy issue.p.8 - The paragraph concerning protein impurities in oils should be in an impurities section.p.9 - What concentrations of Olea Europea (Olive) Fruit Oil were used in the patch tests (references 42-
49)?p.10, Item 3 - It would helpful if CJR staff would do a more complete job of finding published
information regarding the composition of the oils proposed for inclusion in this report.p.10 - In item 4 of Information Sought, what is meant by “specified concentrations”?p.10, Item 5 - As the oils are triglycerides not mixtures of fatty acids, having irritation and sensitization
testing of individual fatty acids is not necessary if the fatty acids are removed from the report.If the fatty acids are left in the report, Cifi staff should look for published information regardingirritation and sensitization of individual fatty acids. Searching PubMed for Linolenic Acid andsensitization the following was the first reference identified.
Kreilling R, Hollnagal HM, Hareng L, et al. 2008. Comparison of the skin sensitizationpotential of unsaturated compounds as assessed by the murine local lymph nodeassay (LLNA) and the guinea pig maximization test (GPMT). Food ChemicalToxicology 46(6): 1896-1904.
p.10 - Request 6 is not clear. If this review is focused only on the composition of the ingredients andthe dermal effects of the ingredients, why is “any other information that pertains to the safety ofuse in cosmetics” necessary? Requests to industry should reflect the same criteria Cifi staffused for identifying information in the published literature. If all types of safety information areneeded from industry, CIR staff need to go back and identify all the relevant published safetyinformation on these oils. Two examples (identified using the NTP website and ToxNet):there is an NTP study on corn oil and safflower oil that is not mentioned in this report, there is adevelopmental study on perilla oil not in the report (Naito et al. 1990. Shokuhin EiseigakuZasshi 3 1(3): 25 1-254).
p.11 - Please provide a reference for Figure 1.
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p.15-18, Table 3 - What is meant by “Araquidic?”? As no oil in the table appears to contain it, it canbe deleted.
p.15-18, Table3, p.19-2!,Table 4 - Rather than arranging these tables in alphabetical order by commonname, these tables should be wTangecl in the same order as tha ingredients are arranged in Table1, alphabetical order by genus species name. Arranging by genus species name will result inspecies of the same genus being presented near each other so similarities among species of thesame genus will be easier to see.
p.16, Table 3, p.20, Table 4 - Reference 60 is for Blackberry Seed Oil (Rubus Fruticosus (Blackberry)Seed Oil) - it is incorrectly called Black Currant Oil in Table 3. Although the company saysthis is an INCI name, it has not been officially assigned and it is not in the Dictionary, nor is iton the list of ingredients included in the report (Table 1). Therefore, the information about thisingredient should be deleted from the report (Tables 3 and 4).
p.18, Table 3, p. 21, Table 4 - As there are several species of strawberries in the Dictionary, the speciesneeds to be identified. Reference 69 indicates that this is Fragaria Ananassa (Strawberry) SeedOil.
p.19-21, Table 4 - Please delete Carrot Seed Oil, Celery Seed Oil and Wild Celery Seed Oil from thistable (and from this report). As discussed above, these essential oils were incorrectly classifiedas fats and oils in the Dictionary. What is the meaning of “*“ with murumuru butter andstrawberry seed oil, and ““ with peach kernel oil?
p.Z2-28, Table 5 - The font used for this table makes it difficult to read.p.29,Table 6 - Please provide references for this table. As ingredients derived from the shea nut are
not included in this report, please delete “shea” from this table. It would be helpful ifinformation about the dietary supplement use for some of these oils, e.g,. Oenothera Biennis(Evening Primrose) Oil, were also provided in this table. If this table is supposed to includeonly non-food, non-cosmetic uses, “substitute for cocoa butter in food” needs to be deletedfrom this table.
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GREEN BOOK 3
Nut Oils
CIR EXPERT PANEL MEETING
AUGUST 30-31, 2010
CIR Panel Book Page 145
CIR Panel Book Page 146
CIR Expert Panel History with Nut Oils June 2010 - CIR issued a Scientific Literature Review.
CIR Panel Book Page 147
Memorandum
To: CIR Expert Panel Members and Liaisons
From: Christina L. Burnett, Scientific Writer/Analyst
Date: July 26, 2010
Subject: Draft Report of the Nut Oil Group
The Scientific Literature Review (SLR) for this group of edible nut oils was announced June 23, 2010. A related SLR on an expansive group of edible plant oils was announced in April of this year, and is to be reviewed by the Panel at this meeting as well. Both reports are taking a slightly new approach to reviewing multiple related ingredients at one time and are including oil ingredients that have previously been reviewed by the CIR Expert Panel, which are designated in italic print.
At the time that the SLR was announced, CIR sought the following additional information:
1. Manufacturing information about oils used in cosmetic formulation, particularly on methods used to remove non-fatty acid components (e.g., glycidol fatty acid esters);
2. Cosmetic grade specifications, if such exist, for oils used in cosmetic formulations.
3. Fatty acid composition for those oils covered in this report (where such information has not been provided or differs from what is presented).
4. Irritation and sensitization testing on cosmetics (finished products) containing specified concentrations of oils covered in this report.
5. Irritation and sensitization testing on those fatty acids present in the oils covered in this report that have previously not been reviewed by CIR.
6. Any other information that pertains to the safety of the use in cosmetics of the oils covered in this report.
Data on cosmetic grade specifications and fatty acid compositions, as well as an HRIPT study on Plukenetia Volubilis Seed Oil have been received from the Personal Care Products Council and are incorporated in this draft report.
Please note that the new use table is being employed in this report. The raw data from which the table was created can be found with the unpublished data.
If the data provided are sufficient for the Panel to assess the safety of these ingredients, a tentative conclusion should be developed regarding their safety in cosmetics, along with a rationale for that conclusion. The report will then be issued as a Tentative Safety Assessment. If additional data are needed, these should be identified and an Insufficient Data Announcement should be issued.
For your convenience, the materials for this report can also be found at http://www.cir-safety.org/aug10.shtml.
CIR Panel Book Page 148
Literature Search on Nut Oils
1
Ingredients Toxline PubMed
ChemIDplus HSDB CAplus NTIS HPV Merck USP
Search Date 5/25/2010 5/26/2010 5/26/2010 5/26/2010 5/27/2010 5/27/2010 5/27/2010 CoconutOil √ √ √ √ √ √ √ PeanutOil √ √ √ √ √ √ √ SachaInchiSd √ √ √ √ √ √ √ SheaOil √ √ √ √ √ √ √ ChileanHzlOil √ √ √ √ √ √ √ GalipSdOil √ √ √ √ √ √ √ BrazilSdOil √ √ √ √ √ √ √ KukuiSdOil √ √ √ √ √ √ √ WalnutSdOil √ √ √ √ √ √ √ PistachioSdOil √ √ √ √ √ √ √ PecanSdOil √ √ √ √ √ √ √ MongongoKrnlOil √ √ √ √ √ √ √ MacadamiaSdOil √ √ √ √ √ √ √ HazelSdOil √ √ √ √ √ √ √ CashewSdOil √ √ √ √ √ √ √ SwtAlmondOil √ √ √ √ √ √ √ Ingredients – All Searched with Chemical Composition, Dermal Toxicity, Irritation and Sensitization qualifiers
CoconutOil – (Limited from Panel’s last review to present day) Coconut Oil; 8001-31-8; Cocos Nucifera Oil; 61788-47-4 Coconut Acid; 68938-15-8; Hydrog Coco Acid; 84836-98-6; Hydrog Coco Oil; 61789-30-8; Potassium (Hydrog) Cocoate; 61789-31-9; Sodium (Hydrog) Cocoate; Magnesium Cocoate; Cocos Nucifera Seed OR Coconut Butter
PeanutOil – (Limited from Panel’s last review to present day) Arachis Hypogaea Oil; 8002-03-7; Peanut Oil; 68425-36-5; Hydrog Peanut Oil; 91051-35-3; Peanut Acid; Potassium OR Sodium Peanutate
SachaInchiSdOil – Plukenetia Volubilis Seed Oil; Sacha Inchi Oil
SheaOil – Shea Oil; 68920-03-6; 194043-92-0; Shea Butter; 225234-14-0; Shea Butter Unsap; Butyrospermum Parkii; Vitellaria paradoxa
ChileanHzlOil – Gevuina Avellana Oil; Chilean Hazel Nut Oil
GalipSdOil – Canarium Indicum Seed Oil; Galip Oil
BrazilSdOil – Bertholletia Excelsa Seed Oil; Brazil Nut Oil
KukuiSdOil – Kukui Nut Oil; 8015-80-3;Aleurites Moluccana Seed Oil; Aleurites Moluccanus Bakoly Seed Oil; Hydrogenated Kukui Nut Oil
WalnutSdOil – Walnut Oil; Juglans Regia Seed Oil; 8024-09-7
PistachioSdOil – Pistachio Nut Oil; Pistacia Vera Seed Oil; 90082-81-8; 129871-01-8
PecanSdOil – Pecan Oil; Carya Illinoensis Seed Oil
MongongoKrnlOil – Mongongo Oil; Schinziophyton Rautanenii Kernel Oil
MacadamiaSdOil – Macadamia Nut Oil; Macadamia Integrifolia Seed Oil; Macadamia Ternifolia Seed Oil; 128497-20-1; 129811-19-4; Hydrog. Macadamia Nut Oil; Sodium Macadamiaseedate
HazelSdOil – (Limited from Panel’s last review to present day) Hazelnut Oil; Corylus Americana Seed Oil; Corylus Avellana Seed Oil; Hydrog Hazelnut Oil
CashewSdOil – Cashew Nut Oil; Anacardium Occidentale Seed Oil; 8007-24-7
SwtAlmondOil – (Limited from Panel’s last review to present day) (Sweet) Almond Oil; Prunus Amygdalus (Dulcis) Oil; 8007-69-0; 90320-37-9; Hydrog Sweet Almond Oil (Unsapon.); Sodium Sweet Almondate
CIR Panel Book Page 149
Report
CIR Panel Book Page 150
Draft Report
Nut Oils as used in Cosmetics
August 30, 2010
The 2010 Cosmetic Ingredient Review Expert Panel members are: Chairman, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D.; Curtis D. Klaassen, Ph.D.; Daniel C. Liebler, Ph.D.; Ronald A Hill, Ph.D. James G. Marks, Jr., M.D.; Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The CIR Director is F. Alan Andersen, Ph.D. This report was prepared by Christina L. Burnett and Monice Fiume, Scientific Analyst/Writers.
© Cosmetic Ingredient Review 1101 17th Street, NW, Suite 412 " Washington, DC 20036-4702 " ph 202.331.0651 " fax 202.331.0088 "
cirinfo@cir-safety.org
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TABLE OF CONTENTS
INTRODUCTION ............................................................................................................................................................................... 1
Chemistry ............................................................................................................................................................................................. 1
Processing .......................................................................................................................................................................... 2
Analytical Methods ............................................................................................................................................................ 2
Impurities ........................................................................................................................................................................... 3
Use ....................................................................................................................................................................................................... 4
Cosmetic ............................................................................................................................................................................ 4
Non-Cosmetic .................................................................................................................................................................... 5
ANIMAL TOXICOLOGY .................................................................................................................................................................. 5
Acute Dermal Toxicity ...................................................................................................................................................... 5
Acute Subcutaneous Toxicity ............................................................................................................................................ 6
Dermal Irritation ................................................................................................................................................................ 6
Arachis Hypogaea (Peanut) Oil..................................................................................................................................... 6
Cocos Nucifera (Coconut) Oil ....................................................................................................................................... 6
Corylus Avellana (Hazel) Seed Oil ................................................................................................................................ 6
Prunus Amygdalus Dulcis (Sweet Almond) Oil ............................................................................................................. 6
Dermal Sensitization .......................................................................................................................................................... 7
Arachis Hypogaea (Peanut) Oil..................................................................................................................................... 7
Cocos Nucifera (Coconut) Oil ....................................................................................................................................... 7
Prunus Amygdalus Dulcis (Sweet Almond) Oil ............................................................................................................. 7
Ocular Irritation ................................................................................................................................................................. 8
Aleurites Moluccana Seed Oil ....................................................................................................................................... 8
Cocos Nucifera (Coconut) Oil, Hydrogenated Coconut Oil, Coconut Acid .................................................................. 8
Prunus Amygdalus Dulcis (Sweet Almond) Oil ............................................................................................................. 8
CARCINOGENICITY ......................................................................................................................................................................... 8
Anacardium Occidentale (Cashew) Seed Oil ................................................................................................................. 9
CLINICAL ASSESSMENT OF SAFETY .......................................................................................................................................... 9
Irritation/Sensitization/Allergenicity ................................................................................................................................. 9
Arachis Hypogaea (Peanut) Oil................................................................................................................................... 10
Butyrospermum Parkii (Shea) Butter and Unsaponifiables ......................................................................................... 10
Cocos Nucifera (Coconut) Oil and Potassium Cocoate .............................................................................................. 11
Hazel Nut Oil ............................................................................................................................................................... 12
Plukenetia Volubilis ..................................................................................................................................................... 12
Prunus Amygdalus Dulcis (Sweet Almond) Oil ........................................................................................................... 12
Phototoxicity/Photosensitization...................................................................................................................................... 13
Cocos Nucifera (Coconut) Oil and Sodium Cocoate ................................................................................................... 13
Prunus Amygdalus Dulcis (Sweet Almond) Oil ........................................................................................................... 13
Clinical Trials/Case Studies ............................................................................................................................................. 13
Aleurites Moluccana Seed Oil ..................................................................................................................................... 13
Anacardium Occidentale (Cashew) Seed Oil ............................................................................................................... 13
Cocos Nucifera (Coconut) Oil ..................................................................................................................................... 14
Macadamia Nut Oil ..................................................................................................................................................... 14
SUMMARY ....................................................................................................................................................................................... 14
FIGURES AND TABLES ................................................................................................................................................................. 17
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INTRODUCTION
Oils derived from edible tree and ground nuts have been safely consumed by humans for millennia. While nuts
themselves may cause allergic reactions in certain individuals, the refined oils derived from the nuts generally pose no
significant safety concern following oral exposure, and their general biology is well characterized due to extensive use in
food materials. Various oils have been used on the skin since antiquity. Initially used for anointing in religious ceremonies,
oils and their components have long been used on the skin for cosmetic purposes. This safety assessment will focus solely on
the basic chemistry, manufacturing/production, uses, and irritation and sensitization data available on these oils as they are
used in cosmetic products. The full list of ingredients this report covers, which includes oils, hydrogenated oils,
unsaponifiables, acids, and simple salts, is found in Table 1. For the sake of brevity, the common name of the oil, when
available, will be used throughout this report. While a large number of oils derived from plants are included in this literature
review, there is a commonality in their structure and composition; they all are triglycerides containing various fatty acids and
fatty acid derivatives, the safety of which in cosmetics have been established.
This report includes the macadamia nut ingredients, Macadamia Integrifolia Seed Oil and Macadamia Ternifolia
Seed Oil, which are described in the International Cosmetic Ingredient Dictionary and Handbook.1 The species M.
integrifolia is currently the only species of macadamia nut that is used for oil production. The name M. ternifolia is an old
naming convention for the edible nut that is currently used to describe a non-cultivated, inedible species.2;3 Macadamia
Integrifolia Seed Oil and Macadamia Ternifolia Seed Oil are the same ingredient. The shea plant also has two species names,
Butyrospermum parkii and Vitellaria paradoxa. Only B. parkii (as Butyrospermum Parkii [Shea] Oil or Butter) is the current
naming convention described by the cosmetics industry.
This report includes cosmetic ingredients that have been previously reviewed by the Cosmetic Ingredient Review
Expert Panel. The ingredients, their conclusion, and published citations are found in Table 2. Previously reviewed fatty
acids and glyceryl triesters are also found in Table 2. A report on the safety of vegetable oils and related ingredients is
currently in CIR’s review process.
CHEMISTRY
This group of cosmetic ingredients characterized as fats and oils are the glyceryl esters of fatty acids (triglycerides)
normally found in plant tissues, including those which have been hydrogenated to reduce or eliminate unsaturation.1 Figure 1
provides the general structure of fats and oils. In additions to triglycerides, tree nut oils are also composed of diglycerides,
monoglycerides, free fatty acids, and other minor components, including natural antioxidants and fat-soluble vitamins.4 The
extent to which these components are removed during processing varies. The available information on chemical properties
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and chemical constituents are found in Tables 3 and 4, respectively. The available fatty acid compositions for the oils in this
report are found in Table 5. The percentage of chemical constituents in individual oil types is dependent on region where the
nut plant is grown, individual cultivars, and plant genetics.5 The nutritional content of these oils varies with oil type, also.
In a study by Lodén and Andersson, shea butter “liquid” contained 9% unsaponifiable lipids, mainly triterpene esters
and sterol esters with cinnamic acid (as determined by high performance liquid chromatography). 6 The unsaponifiable
fraction in this study contained 22% unsaponifiable lipids, out of which 40% consisted of triterpene and sterol esters with
cinnamic acid.
Processing
Oils used in cosmetics are probably produced using the same process used in the food industry. Depending on the
source, oil may be directly expressed from the source (seed or pulp) followed by solvent extraction. Bailey states that the
removal of pigments and polar materials is mandatory for most cosmetic applications.7 The process used for oil refining for
foods may be adequate for this purpose, or additional steps may be required. Special refining methods to yield colorless and
odorless oils are used by the cosmetic industry and include proprietary adsorption chromatography and supercritical fluid
extractions.
The majority of the oils presented in this report are produced either from mechanical extraction or solvent extraction
or a hybrid of both methods, known as prepress solvent extraction.5 In solvent extraction, hexane is the most commonly used
solvent as it is economical and has low toxicity potential when compared to other solvents.
After the initial extraction by methods such as solvent extraction, the crude (degummed) oil is often refined.5 The
first step is treating the oil with caustic soda to neutralize free fatty acids, hydrolyze phosphatides, and remove some colored
pigments and unsaponifiable materials. Soap stock is usually a by-product of this step. The next step involves bleaching the
neutralized oil with activated earth to further absorb pigments. The last major step in refining oil is deodorizing, which
removes all oxidative cleavage products that impart odor or flavor to the oil. Deodorization also removes tocopherols,
sterols, and other minor constituents of free fatty acids and undesirable foreign materials. Figure 2 is a flowchart of the basic
refinement process.
After deodorization, oils can be further processed by hydrogenation, which makes oil more resistant to oxidative and
thermal damage, and by winterization, where oil is slowly cooled to promote formation of crystals that cause cloudiness and
filtered to remove the crystals.
Analytical Methods
Near infrared spectroscopy and gas chromatography have been used, respectively, to phenotype and analyze fatty
acid profiles in shea fat (described as Vitellaria paradoxa, not Butyrospermum parkii).8 The fatty acid composition of
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hazelnut oil (Corylus avellana, in crude form) has also been analyzed by gas chromatography.9 The triacylglycerol and
diacylglycerol composition oils from hazelnut, pistachio, almond, Brazil nut, and macadamia nuts have been characterized
with high-performance liquid chromatography with atmospheric pressure chemical ionization and UV detection.10 The
triacylglycerol profile of Brazil nut oil has also been quantified using dry matrix-assisted laser desorption/ionization time-of
flight mass spectrometry.11 According to Crevel et al., a validated analytical methodology for establishing the protein content
of oil is needed.12
Impurities
Proteins
Many edible oils are derived from foods that are recognized as potent food allergens. It has been shown that often
an individual that is allergic to a food will generally not react to the refined oil, especially if the oil has been “hot-pressed” or
has undergone more processing.12;13 It should be noted that while the Panel has found a general lack of clinical effects for nut
oils that they have already reviewed,14;15 other researchers have raised concerns about the presence of residual proteins in nut
oils. Olszewski et al. found 0.1-0.2 µg protein per g of peanut oil,16 while Ramazzotti et al. reported finding IgE responsive
residual proteins in peanut oil extracts. 17 The European Medicines Agency (EMEA) Working Party on Herbal Medicinal
Products concluded that peanut products “should be treated as allergenic unless they have an analytically-monitored non-
allergenic specification and a safe maximum daily dose.”18 The EMEA found that threshold concentrations for induction of a
protein contact dermatitis were not available and recommended that “all medications for topical use containing peanut
products should be treated as allergenic.”
Aflatoxin
Aflatoxins are metabolic products of the molds Aspergillus flavus and Aspergillus parasiticus. They are most often
produced in stored agricultural crops (such as peanuts and other nut crops) when growth conditions and genetic requirements
are favorable.19-21 Aflatoxins are identified as B1, B2, G1, G2, M1 and M2 (milk toxins), B2a, and G2a based on fluorescent
color (B = blue, G = green) when separated chromatographically. Aflatoxins B3, R0, P1, Q1, RB1, RB2 and D1 have also been
isolated.20
The International Agency for Research on Cancer (IARC) categorized aflatoxins as group 1 agents, “carcinogenic to
humans”.22;23 Epidemiological studies noted “positive correlation between estimated aflatoxin intake or level of aflatoxin
contamination of market food samples and cooked food and incidence of hepatocellular cancer.” The observations were
supported by positive results in laboratory carcinogenicity and mutagenicity studies. Aflatoxin B1 specifically is recognized
as “one of the most potent environmental mutagens and carcinogens known”.20 Aflatoxin B1 and B2 are the most common
aflatoxins found in peanuts.24
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The United States government places the following limitations on peanuts to be considered “negative” for aflatoxin:
< 15 ppb for “peanuts which have been certified as meeting edible quality grade requirements” and < 25 ppb for “non-edible
quality categories” (7 CFR Sections 997.30 and 998.200). The FDA has defined the action levels for aflatoxin content in
foods at 20 ppb.25
A study reported that crude peanut oil (obtained by solvent extraction or hydraulic pressing) has reduced aflatoxin
concentration compared to peanut kernels, and that subsequent processing (alkali refining and bleaching) reduces the
concentration still further.14 In one example, processed peanut oil from moldy peanuts (contaminated with 5500 ppb
aflatoxin) had an aflatoxin concentration of < 1ppb. [From CIR assessment on peanut oil, 2001.]
In 50 samples of hazel nuts from Spain, all samples showed fungal contamination, but no aflatoxin contamination.26
Of the 50 fungal strains identified, 25 were aflatoxigenic strains. In 20 hazel nut samples collected in Egypt, however,
aflatoxin (25-175 µg/kg) was reported as a contaminant in 90% of samples. [From CIR assessment on hazel seed oil, 2001.]
Aflatoxin contamination of raw and dried coconut copra has been reported.15 Improper drying, handling, and
storage greatly increase the possibility of contamination by aflatoxins growing on copra. Smoke drying of copra inhibited
aflatoxin formation. [From CIR assessment on coconut oil, 2008.]
USE
Cosmetic
The available use information supplied to the Food and Drug Administration (FDA) by industry as part of the
Voluntary Cosmetic Registration Program (VCRP) on these oil ingredients can be found in Table 6.27 Shea butter has the
most reported uses in cosmetic and personal care products with a total of 1950. A recent survey of use concentrations for shea
butter reports a maximum use concentration of 60% in leave-on products as a cuticle softener, a manicuring application.28 A
survey of use concentrations in the remaining ingredients discussed in this report is currently being conducted by the Personal
Care Products Council (Council). The use concentrations that were reported in previous CIR safety assessments of oils are
also found in Table 5.14;15;26;29 (The year the data were reported is included in parentheses; if no date is available, the data is
current.) Although hazel nut oil (Corylus Americana and Corylus Avellana) were previously reviewed, specific
concentration of use data were not available. One source reported Corylus Avellana seed oil was used up to 100%. Non-
specific hazel nut oil concentration of use ranged from <5% to 50% according to historical FDA data.26
Oils are used in a wide variety of cosmetic products for their skin conditioning, occlusive, emollient, moisturizing
and other properties. The oil ingredients described in this report may be used in hair sprays, and effects on the lungs that may
be induced by aerosolized products containing these ingredients are of concern.
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The aerosol properties that determine deposition in the respiratory system are particle size and density. The
parameter most closely associated with deposition is the aerodynamic diameter, da, defined as the diameter of a sphere of unit
density possessing the same terminal settling velocity as the particle in question. In humans, particles with an aerodynamic
diameter of ≤ 10µm are respirable. Particles with a da from 0.1 - 10µm settle in the upper respiratory tract and particles with
a da < 0.1 µm settle in the lower respiratory tract.30;31
Particle diameters of 60-80 µm and ≥80 µm have been reported for anhydrous hair sprays and pump hairsprays,
respectively.32 In practice, aerosols should have at least 99% of their particle diameters in the 10 – 110 µm range and the
mean particle diameter in a typical aerosol spray has been reported as ~38 µm.33 Therefore, most aerosol particles are
deposited in the nasopharyngeal region and are not respirable.
None of the oils or their related counterparts described in this report were restricted from use in any way under the
rules governing cosmetic products in the European Union.34
Non-Cosmetic
The primary uses for nut oils are for cooking. Of the nut oils, peanut oil and coconut oil are the world's most widely
consumed.5;35 Non-food, non-cosmetic uses for edible nut oils are found in Table 7.
ANIMAL TOXICOLOGY
Irritation, sensitization and phototoxicity information were not found for all the oils listed in this report. The data
available were reviewed and are summarized below. Information from previous CIR reports on nut oils is identified by
italics.
Acute Dermal Toxicity
Cocos Nucifera (Coconut) Oil
Undiluted hydrogenated coconut oil was applied as a single dose of 3 g/kg to the skin of 12 guinea pigs.15 No
deaths occurred during the 7-d observation period.
Prunus Amygdalus Dulcis (Sweet Almond) Oil
Undiluted sweet almond oil was tested for acute dermal toxicity in guinea pigs.36 The test material was applied
under occlusion to the clipped abraded and intact skin of 12 animals (6 male/6 female) at a dose of 3 g/kg. At 24 hours,
excess material was rinsed off. Observations were made daily for seven days; animals were then killed and necropsied. The
acute dermal LD50 was > 3 g/kg.
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Acute Subcutaneous Toxicity
Prunus Amygdalus Dulcis (Sweet Almond) Oil
Guinea pigs were injected subcutaneously with single or multiple doses of a 10% sweet almond oil emulsion in
saline (1 ml/dose).36 After a single injection, minute oil emboli were found in the lungs of these animals. After six to ten
hours, emboli caused local infiltration of eosinophils in the lung parenchyma. Six days after repeated oil injections,
investigators observed a peripheral blood eosinophilia, which reached a maximum increase of 16.5% by the third week. The
eosinophilia was suggested to be a nonallergic reaction.
Dermal Irritation
Arachis Hypogaea (Peanut) Oil
Undiluted technical grade peanut oil was moderately irritating to rabbits and guinea pig skin and mildly irritating
to rat skin following exposure; there was no indication that the test site was occluded. However, in a 48 h occlusive patch
test using miniature swine, technical grade peanut oil was not irritating.14
Cocos Nucifera (Coconut) Oil
Undiluted coconut oil, hydrogenated coconut oil, and coconut acid were non- to minimally irritating to rabbit skin.
In single-insult occlusive patch tests of a 5% aq. solution of a bar soap containing 13% sodium cocoate, scores of 1.6-4.0/8.0
were reported.15
Corylus Avellana (Hazel) Seed Oil
A comedogenicity study was conducted in which 0.1 ml of Corylus Avellana (hazel) nut oil (pH 6) was applied to the
internal fold and the pinna of the right ear of 6 albino rabbits, 5 days per week for 2 weeks.26 Animals were killed at the end
of the study and epidermal samples were obtained from both ears of each rabbit. The samples were examined both by a
magnifying glass and microscopically. No local irritation was noted at the application site. A “slight difference in the
number and size of the pilosebaceous follicles” was noted via magnifying glass. A “slight excess of sebum and a dilation of
the follicles” was noted upon microscopic examination of the treated areas.
Prunus Amygdalus Dulcis (Sweet Almond) Oil
Undiluted sweet almond oil was tested for irritancy in groups of 6 male albino rabbits.36 The test material was
applied under occlusion to the clipped intact and abraded dorsal skin of each animal. Twenty-three hours later, patches
were removed; sites were scored at 24 and 48 hours. The Primary Irritation Indices (PIIs) for seven test samples of Sweet
Almond Oil ranged from 0 to 0.18 (maximum score = 8), indicating that this ingredient is practically nonirritating to skin.
Undiluted sweet almond oil and two moisturizer formulations each containing 25% sweet almond oil were tested for
skin irritancy by the following procedure.36 The test material was applied under occlusion to the shaved intact dorsal skin of
groups of 9 female albino rabbits. Patches were removed and sites were scored for erythema at 24 and 72 hours. Undiluted
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sweet almond oil was nonirritating (PII = 0; maximum score = 4); whereas, the formulations containing 25% sweet almond
oil were minimally irritating (PIIs = 0.28 and 0.72, respectively).
A 60-day cumulative irritation test was used to evaluate the subchronic irritancy of sweet almond oil in rabbits.36
The test material, at concentrations of 10% or 100%, was applied daily to the clipped dorsal skin of groups of 3 albino
rabbits. Sites were scored daily. When tested in 7 separate trials, 100% sweet almond oil produced mean maximum
irritation indices (MMIIs) ranging from 0.34 to 1.34 (maximum score = 8). At a concentration of 10%, MMIIs for this
ingredient ranged from 0 to 0.66. Results indicated that, when applied to the skin over a long period of time, undiluted sweet
almond oil is slightly irritating; whereas, at 10% it is practically nonirritating.
Dermal Sensitization
Arachis Hypogaea (Peanut) Oil
Hartley and/or Himalayan guinea pigs were used to determine the sensitization potential of peanut oil. Single drops
of a store-bought peanut oil were applied to an area clipped free of hair on the backs of 4 guinea pigs. Applications were
made at 2-6 wk intervals, for a total of 7 applications over a 5-mo period. It appears that the test sites were not covered. The
test sites were scored 24 h after application. Well-defined erythema was considered a positive reaction. None of the animals
had a positive reaction following the initial application. Two animals had positive reactions following application at wks 6
and 12, while one animal had a positive reaction following dosing at wk 12 only.14
Cocos Nucifera (Coconut) Oil
In guinea pigs, neither undiluted coconut oil or hydrogenated coconut oil were sensitizers.15
Prunus Amygdalus Dulcis (Sweet Almond) Oil
A maximization assay was used to determine the sensitizing potential of sweet almond oil.36 Hartley-strain female
guinea pigs were divided into groups of 10 animals. Each animal received intradermal injections of 50% aqueous Freund’s
complete adjuvant (FCA), 5% sweet almond oil in propylene glycol, and 5% sweet almond oil in 50% FCA into different sites
on epilated dorsal skin. Vehicle control animals were also used. In the dose-range phase of the experiment, each of 50
animals received a single dermal application of 5%, 10%, or 100% sweet almond oil to determine “subirritating” and
“slightly irritating” concentrations to be used for the challenge and booster phases. One week after the induction injection,
100% sweet almond oil was applied occlusively to the treated sites for 48 hours as a topical booster. Animals were
challenged 2 weeks later with 5% sweet almond oil in petrolatum applied topically under occlusion for 24 h. Patches were
then removed and sites were scored 24 and 48 h later. Sweet almond oil was nonsensitizing under these test procedures.
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Ocular Irritation
Aleurites Moluccana Seed Oil
In in vitro human conjunctival cell assays and in vivo guinea pig Draize tests, Aleurites Moluccana oil was not
cytotoxic and was not an ocular irritant.37 The same authors tested the efficacy of Aleurites Moluccana oil in ocular burn
treatment in vitro and in vivo and did not observe any adverse effects.38
Cocos Nucifera (Coconut) Oil, Hydrogenated Coconut Oil, Coconut Acid
Undiluted coconut oil was instilled into the conjunctival sac of the eyes of each of 2 groups of rabbits (6
rabbits/group). Without subsequent water rinsing of the eyes, maximum irritation scores of 2 and 1 were reported for the 2
treatment groups (max = 110). These results were indicative of minimal eye irritation.15
Undiluted hydrogenated coconut oil was instilled into the eyes of 10 groups of 6 rabbits each in a single dose. The
treated eyes received no subsequent water rinse. In 1 test, mild irritation (6/110) was observed. The eyes appeared normal by
the fourth day. In another study, minimal irritation (2/110) was observed, and the eyes appeared normal by the third day. In
eight tests, negligible or minimal irritation was observed. The eyes were clinically normal by the second day.15
Tests of 2 lipstick formulations containing 10% hydrogenated coconut oil were conducted with 6 albino rabbits
each. Slight conjunctivitis was observed from both formulations (no score provided), but the reaction disappeared by 48 and
24 h, respectively. Undiluted coconut acid was assayed for ocular toxicity in 3 groups of 6 rabbits each. In 2 tests, mild
irritation (8/110 and 9/110) was observed. The eyes were considered normal by the fourth day. In 1 test, minimal irritation
(1/110) was observed, with the eyes returning to normal by the third day.15
Prunus Amygdalus Dulcis (Sweet Almond) Oil
The Draize method or a modification of it was used to test the eye irritancy of undiluted sweet almond oil and
cosmetic formulations containing up to 25% sweet almond oil.36 The test material was instilled into one eye of each of 3 to
6 rabbits; the other eye served as an untreated control. Irritation was evaluated 1 h, as well as 1, 2, 3, 4, and 7 days later.
Undiluted sweet almond oil was practically nonirritating or minimally irritating. Formulations containing up to 25% sweet
almond oil were nonirritating to minimally irritating. In most instances, reactions that occurred were limited to conjunctival
irritation, which cleared by the third day of observation.
CARCINOGENICITY
The safety of glycidol fatty acid esters in refined vegetable oils was assessed by IARC. Glycidol was determined to
be a Group2A (probably carcinogenic to humans) chemical while Glycidol Fatty Acid Esters was determined to be a Group 3
(not classifiable as to carcinogenicity to humans) chemical.39;40
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The Federal Institute for Risk Assessment in Germany released a summary of their initial evaluation of the
assessment of levels of glycidol fatty acid esters detected in refined vegetable fats.41 While acknowledging that the levels of
glycidol that may be released from glycidol fatty acid esters are not known, the evaluation noted that glycidol is classified as
probably carcinogenic to humans. The evaluation was based on findings of the German Chemical and Veterinary Test
Agency (CVUA).
In a presentation by Weisshauer from the CVUA, the conversion of glycidol to 3-chloropropanediol was presented
as an artifact of the analytical method, and it appeared to be the 3-chloropropanediol that was detected its indicative of the
presence of glycidol.42 The levels of 3-chloropropanediol were negligible at the crude oil, degummed, neutralized, and
bleached stages, but levels were significant at the deodorized stage.
Anacardium Occidentale (Cashew) Seed Oil
Singh et al. investigated the modulatory effect of cashew nut oil on antioxidant potential in female Swiss albino
mice in a 120 day skin papillomagenesis study.43 The mice were divided into 4 groups of 15 and 1 group of 10 (vehicle
control). Test groups were as follows: Group I was the vehicle control, receiving 0.1 ml acetone; Group II was the positive
control, receiving a single dose of 7,12-dimethylbenz(a)anthracene (DMBA) (0.005 mg/0.05 ml acetone ) followed by
applications of 2% croton oil 3 times a week until study termination; Group III received a single dose of DMBA followed by
applications of 2.5% cashew nut kernel oil 3 times a week until study termination; Group IV received a single dose of DMBA
followed by applications of 5% cashew nut kernel oil 3 times a week until study termination; and Group V was 5% cashew
nut kernel oil applied until study termination. The oil was applied to the clipped dorsal scapular region that was 2 cm in
diameter. Body weights were recorded at regular intervals. Skin papillomas greater than 1 mm in diameter at the application
sites were recorded weekly and included in the data analysis if they persisted for more than 2 weeks. The positive control
group yielded expected results (86% tumor incidence). No tumors were observed in the vehicle control or the other test
groups. The authors concluded that cashew nut kernel oil did not exhibit any solitary carcinogenic activity.
CLINICAL ASSESSMENT OF SAFETY
Edible oils, including nut oils, are commonly believed to be safe for use on the skin.7 de Groot notes that no
documentation exist to show that high quality edible lipids cause adverse reactions in normal individuals (except for potential
comedogenicity).44 Very few reports of adverse reactions to cosmetic use of edible oils have been reported.
Irritation/Sensitization/Allergenicity
Many edible oils are derived from foods that are recognized as potent food allergens. It has been shown that often
an individual that is allergic to a food will generally not react to the refined oil, especially if the oil has been “hot-pressed” or
has undergone more processing.12;13 A prime example is peanut oil. Peanuts are extremely allergenic to a large population,
CIR Panel Book Page 161
10
but reaction to the oil is rare. In the original safety assessment on peanut (Arachis hypogaea) oil, the Expert Panel noted that
the major concern associated with allergic reactions to peanuts is the protein.14 The protein does not partition into the refined
oil, and therefore, oil does not raise the same type of safety concerns as the food containing oil and protein. Crevel et al. also
concluded that chemically refined peanut oil is safe for the majority of peanut allergic individuals.12 They stated that “as
peanut is acknowledged to be one of the most potent food allergens, it is reasonable to extrapolate the conclusions drawn up
for peanut oil to other edible oils.” However, they concede that validated analytical methodology for establishing the protein
content of oil is needed.
In support of the conclusions stated earlier, Crevel et al. also examined the allergenicity of some other oils. Very
few instances of allergic reactions to other major edible oils have been reported. Even sesame oil, which differs from the
other oils in that it is used as a flavorant and therefore is not as refined and expected to contain significantly more protein that
the other edible oils, has had very few reports of allergic reaction.
The preceding paragraphs addressed general allergenicity issues of edible oils. Specific information, where
available, follows and is either summarized from previous CIR reports on edible oils, and is identified by italics, or is new
data and identified by normal text.
Arachis Hypogaea (Peanut) Oil
The sensitization potential of a topical dermatologic product containing 0.01% fluocinolone and refined peanut oil
was studied in peanut-sensitive children and adults.45 The volunteers for the study included 8 children and 6 adults. The
subjects first underwent a prick skin test with peanut extracts, a solution of 50% glycerin (negative control), a solution o f 1.8
mg.ml histamine phosphate in 50% glycerin (positive control) the complete test product, the product’s vehicle only (without
fluocinolone), and refined peanut oil. Wheals that appeared were measured and recorded after 15 minutes. The subjects
were also patch tested with the complete test product, the product’s vehicle only, and the refined peanut oil. The materials
were applied with Finn chambers on the mid-back, were left in place for 48 h, removed, and observed immediately and after
24 h. Only 1 child had a trace positive reaction to refined peanut oil in the prick skin test. There were no reactions in any of
the subjects to the test product, product vehicle, or the negative control; positive results were observed to the positive control
and the peanut extracts. All subjects had negative patch tests at 48 and 72 h.
Butyrospermum Parkii (Shea) Butter and Unsaponifiables
The effect of a single application of 9 different lipids, including shea butter and fractions of unsaponifiable lipids
from shea butter, on “normal” skin and sodium lauryl sulfate (SLS)-irritated skin was studied in 21 healthy subjects.6 The
shea butter “liquid” sample was obtained from a supplier and the unsaponifiable fraction was obtained through low
temperature crystallization of the supplied sample. The right volar forearm was treated with 50 µl of each test material in 12
CIR Panel Book Page 162
11
mm Finn chambers for 48 h. The left volar forearm was treated with 50 µl of 14% aq. SLS for 7 h, rinsed, dried, and then
treated with 50 µl of each test material for 17 h. The treated areas were then washed with mild soap solution, dried, and
examined after 24 h. Visible signs of irritation were assessed and cutaneous blood flow and transepidermal water loss
(TEWL) were measured.
In the normal skin treated with shea butter, barely perceptible erythema was observed in a small number of subjects
(number not reported) 24 h after patching. No irritation from the shea unsaponifiable fraction was observed in any of the
subjects. In the SLS-irritated skin treated with shea butter, 7 subjects had no irritation reaction, 6 had barely perceptible
erythema, 7 had slight erythema, and 1 had moderate erythema. In the SLS-irritated skin treated with shea unsaponifiable
fraction, 9 subjects had no irritation reaction, 8 had barely perceptible erythema, and 2 subjects each had slight and moderate
erythema. No significant differences in cutaneous blood flow or TEWL were observed in shea butter and shea unsaponifiable
fraction when compared to water (control) in either normal or SLS-irritated skin.6
Cocos Nucifera (Coconut) Oil and Potassium Cocoate
A bar soap containing 13% coconut oil was evaluated for skin irritation using standard Draize procedures. One
percent aqueous solutions of the product were applied with occlusive patches to the forearms of 106 panelists over a 3-wk
period. Very minimal skin reactions were recorded, and the researchers concluded the material was not hazardous under
conditions of normal use.15
Bar soaps containing 13% coconut oil were evaluated in a 2-week normal use test. The investigators reported no
unusual irritation response under normal use conditions in 72 panelists.15
Soap chamber tests employing Duhring chambers applied to the forearm were conducted with 8% aqueous
suspension of bar soaps containing 13% coconut oil. One 24-h patch and four 6-h patches were applied over a 5-d period.
In one test with 10 panelists the soap was moderately irritating, and the researchers concluded it was safe under conditions
of normal use. In a second soap chamber test, minimal irritation was observed in a panel of 10 individuals.15
The skin of 40 healthy volunteers and 480 subjects with active skin diseases were patch tested with 15 µL of 5%
aqueous potassium cocoate. Positive responses were observed in 5 subjects (0.9%). Intensities of the positive responses
were not reported; however, 2 subjects had active psoriasis and 3 had active eczema.15
A tanning butter containing 2.5% coconut oil was evaluated using a repeat insult predictive patch test. Nine 24-h
induction patches were applied over a 3-week period. No erythematous reactions were observed in 103 panelists after a
single challenge in the sixth wk of the study.15
Four lipstick formulations containing 10% hydrogenated coconut oil were tested with a single 48-h application on
204 white females. There was no evidence of primary irritation and no indication of sensitization on retests performed 14 d
CIR Panel Book Page 163
12
later. 15
Coconut oil was not an allergen at 100% concentration in 12 subjects in a double-blind randomized controlled pilot
study.15
Hazel Nut Oil
A patch testing reference book by de Groot noted that the published literature does not contain recommended test
concentrations concerning hazel nut oil.26 To serve as a guide to the reader, de Groot reported that an unpublished (and at
the time, ongoing) study found no irritant reaction in 1 to 20 patients suffering from or suspected to suffer from cosmetic
product contact allergy who had been patch tested with 30% hazel nut oil in petrolatum.
Plukenetia Volubilis
A human repeat insult patch test (HRIPT) was performed on a lipstick containing 0.51% Plukenetia Volubilis seed
oil in 108 subjects.46 The test material (0.2 g) was applied to the upper back with a ¾ inch square absorbent pad and
occluded. A total of 9 applications were applied for 24 h over a 3-week period during the induction phase. After a 2-week
resting period, a challenge patch was applied to a virgin site for 24 h and the test site was scored at 24 and 72 h post-
application. No reactions were observed and it was concluded that the lipstick containing 0.51% Plukenetia Volubilis seed
oil was not a dermal irritant or sensitizer.
Prunus Amygdalus Dulcis (Sweet Almond) Oil
A single insult patch test (SIPT) was used to determine the irritancy of undiluted sweet almond oil.36 The test
material was applied under occlusion to the backs of 101 subjects; 48 h later, the patches were removed and the sites scored.
Sweet almond oil produced no reactions in the test subjects and was determined to be nonirritating.
A HRIPT was used to study the irritancy and sensitizing potential of undiluted sweet almond oil in 52 subjects.36
The test material was applied under occlusion to the back of each subject for 48 h; sites were then read and the compound
reapplied. This procedure was repeated 3 days per week for 3 weeks (9 applications). Following a 2-week rest, 1 or 2
challenge patches were applied to previously untreated skin of each subject. Sites were scored 48 and/or 96 h later.
Undiluted sweet almond oil produced no reactions in any of the 52 subjects and was concluded to be nonirritating and
nonsensitizing.
Repeated insult patch tests were used to study the effects of cosmetic formulations containing 0.1%-25% sweet
almond oil in a total of 6906 subjects.36 Results indicate that these products are practically nonirritating and nonsensitizing
to human skin. Additionally, the Lanman-Maibach 21-day Cumulative Irritancy Assay was used to test the subchronjc
irritancy of a moisturizer containing 25% sweet almond oil. The test material was applied under occlusion to the backs of 10
subjects for 23 hours. Patches were then removed, the site rinsed and scored 1 h later, and the compound reapplied. This
CIR Panel Book Page 164
13
procedure was repeated for 21 consecutive days. Of the 10 subjects tested, 7 reacted to 1 or more patches. The total
irritancy score was 14 out of a maximum possible 630.
Phototoxicity/Photosensitization
Cocos Nucifera (Coconut) Oil and Sodium Cocoate
Bar soaps made with 13% coconut oil were tested as a 3% aqueous solution. Patches containing 0.2 ml were
applied 3 times a week for 24 h for a 3-wk period to stripped skin. Sites were exposed to a Wood's lamp for 40 min and a sun
lamp for 15 min following each application. Following a 2-week nontreatment period, duplicate challenge patches were
applied. No evidence of photosensitization was observed in any of the 10 panelists.15
A similar soap prepared as 1 or 3% aqueous solutions was tested on 52 panelists. Occlusive patches containing 0.4
ml of the test solution were applied to the arms 3 times a week for a 3-week period. Sites were exposed to sunlight for 30 min,
24 h after application. Following a 2-week nontreatment period, duplicate challenge patches were applied. Sun exposures
were made 24 h following the challenge application. No evidence of photosensitization was noted.15
Bar soaps made with 13% sodium cocoate were prepared as a 3% aqueous solution. Occlusive patches containing
0.2 ml of the test solution were applied to the tape-stripped backs of 10 volunteers over a 6-week period. After each
application, the treated sites were exposed to an inspectrolamp for 45 min. After UVA exposure, the area was exposed to
about 2/3 of the minimal erythemal dose (MED) from an air-cooled Kromayer lamp. No evidence of phototoxicity was
observed.15
Prunus Amygdalus Dulcis (Sweet Almond) Oil
Formulations containing 0.1% - 2.0% sweet almond oil were tested for photosensitization in a total of 764 subjects.
The test material was applied under occlusion to each subject’s back.36 Twenty-four hours later, the patch was removed and
the site scored and irradiated with ultraviolet light from a 150W Xenon Arc Solar Simulator (290-400 nm) at a dose equal to
3 times the individual’s minimal erythema dose (MED). The site was again graded at 72 h and the procedure repeated once.
The products containing 0.1% - 2% sweet almond oil did not manifest photosensitivity in any of the test subjects.
Clinical Trials/Case Studies
Aleurites Moluccana Seed Oil
In an efficacy study of Aleurites Moluccana oil as a topical treatment for psoriasis, 15 patients with mild, stable
plaque psoriasis (less than 15% total body surface area) applied “just enough (oil) to moisten the plaque” 3 times daily for 12
weeks. No side effects or adverse events were reported.47
Anacardium Occidentale (Cashew) Seed Oil
A 37-year-old male resin researcher presented with painful, edematous erythema with bullae on his right leg after
dropping pure cashew nut oil from a bottle on his right thigh.48 He had removed his clothes immediately and thoroughly
CIR Panel Book Page 165
14
washed the skin. The erythema developed 10 days after exposure. Patch testing was performed with cashew nut oil 3%
alcohol, cashew nut oil 0.3% alcohol, cashew nut oil 0.03% alcohol, and urushiol 0.01% petrolatum. The patients had a “+”
reaction on day 2 and “++” reactions on days 3 and 4 to the 3% dilution, and “+” reactions to the 0.3% dilution and urushiol
on days 2-4. A “?+” reaction was observed on days 2 and 3 and a “+” reaction was observed on day 4 to the 0.03% dilution.
Cocos Nucifera (Coconut) Oil
Coconut oil did not produce adverse effects in several therapeutic studies.15
Macadamia Nut Oil
A case of cheilitis was reported in a 28-year-old woman that had used a lipstick that contained macadamia nut oil
(no species description or concentration of oil were reported).49 When patch tested with the ingredients contained in the
lipstick, the patient had positive reactions to di-isostearyl malate and macadamia nut oil. The patient was told to discontinue
use of lipsticks containing these 2 ingredients and her condition improved with steroid ointment.
SUMMARY
The oils derived from edible nuts are composed of mono-, di-, and triglycerides, free fatty acids and other minor
components, including natural antioxidants and fat-soluble vitamins. The percentage of chemical constituents and nutritional
content of individual oil types is dependent on region where the nut plant is grown, individual cultivars, and plant genetics.
Oils used in cosmetics are likely produced in the same manner as those used in the food industry. Oils may be expressed
through mechanical or solvent extraction. The oils may undergo further refining to remove pigments, odors, unsaponifiable
materials, and other undesirables.
It has been shown that often an individual that is allergic to a food will generally not react to the refined oil. The
CIR Expert Panel has found a general lack of clinical effects for edible nut oils that they have already reviewed; however,
other researchers have raised concerns about the presence of residual proteins in oils, such as peanut and soy. These
ingredients may also contain aflatoxins, a metabolic products of certain molds that are carcinogenic to humans. The FDA
action level for aflatoxin in foods is 20 ppb.
Of the nut oils described in this report, shea butter has the most reported uses in cosmetic and personal care products
with a total of 1950 and is used at a maximum concentration of 60% in leave-on products with manicuring applications. Nut
oils are used in a wide variety of cosmetic products for their skin conditioning, occlusive, emollient, moisturizing, and other
properties. These ingredients may be used in hair spray and other aerosolized products. None of the oils or the related
counterparts described in this report were restricted from use in the European Union.
CIR Panel Book Page 166
15
In acute animal studies, undiluted hydrogenated coconut oil and undiluted sweet almond oil were not dermal
toxicants in dermal toxicity studies in guinea pigs at doses of 3 g/kg. In a subcutaneous toxicity study, 10% sweet almond oil
produced nonallergic eosinophilia reactions in guinea pigs.
Undiluted peanut oil was moderately irritating to rabbits and guinea pig skin, mildly irritating in rat skin, and non-
irritating in miniature swine in dermal studies. Undiluted coconut oil, hydrogenated coconut oil, and coconut acid were non-
to minimally irritating in rabbit skin. Corylus Avellana (hazel) nut oil was not irritating to rabbit skin. Sweet almond oil at
25% in formulations was minimally irritating; at 10%, it was practically non-irritating, and at undiluted concentrations, it was
practically non-irritating to slightly irritating.
In animal sensitization studies, store-bought peanut oil produced well-defined erythema only at 12 weeks in a 5
month guinea pig study. Undiluted coconut oil and hydrogenated coconut oil were not sensitizers in guinea pig studies.
Sweet almond oil up to 100% was not sensitizing in a guinea pig study.
Aleurites Moluccana seed oil was not cytoxic or irritating in in vitro and in vivo ocular efficacy studies. Undiluted
coconut oil and undiluted hydrogenated coconut oil were minimal to mild eye irritants in rabbit eyes, while formulations
containing 10% hydrogenated coconut oil produced slight conjunctivitis in rabbit eyes that disappears after 24-48 h.
Undiluted sweet almond oil and formulations containing up to 25% sweet almond oil were nonirritating to minimally
irritating in Draize studies.
Glycidol and glycidol fatty acid esters, possible constituents in refined vegetable and nut oils, were determined to be
Group 2A (probably carcinogenic to humans) and Group 3 (not classifiable as to carcinogenicity to humans) chemicals,
respectively, by IARC. Cashew nut oil did not exhibit solitary carcinogenic activity in a study of the modulatory effect on
the antioxidant potential of this nut oil.
Edible nut oils are believed to be safe for use on the skin and very few reports of adverse reactions have been
reported. While the nuts that these oils are derived from are recognized food allergens, the proteins that are responsible for
allergenic responses do not partition into refined oils.
In 14 peanut-sensitive subjects, only one trace positive reaction was observed to refined peanut oil in a prick skin
test, but no reactions were observed in patch tests. Barely perceptible erythema was observed after exposure to shea butter on
normal skin while no irritation was observed following exposure to shea unsaponifiable fractions.
Bar soaps containing 13% coconut oil, when tested using standard Draize procedures, produced very minimal skin
reactions. In a 2-week normal use test, the bar soaps caused no unusual irritation response. The results of soap chamber tests
of bar soaps were minimal irritation in one study and mild irritation in another. A tanning butter containing 2.5% coconut
oil did not cause erythematous reactions in a 6-week repeat insult predictive patch test. Lipstick containing 10%
CIR Panel Book Page 167
16
hydrogenated coconut oil caused no evidence of primary irritation after a single patch application and no indication of
sensitization in retests performed 14 days later. Coconut oil was not an allergen at 100% concentration in 12 subjects in a
double-blind randomized controlled pilot study.
No irritation was observed in patients that were patch tested with 30% hazel nut oil. Irritation and sensitization was
not observed in subjects tested with 0.51% Plukenetia Volubilis seed oil in a HIPT. Undiluted sweet almond oil was non-
irritating and nonsensitizing in SIPT and RIPT studies, and formulations containing 0.1%-25% sweet almond oil were
practically nonirritating and nonsensitizing to human skin.
Bar soaps containing up to 13% coconut oil or sodium cocoate were not photosensitizers in human subjects, nor
were formulations containing 0.1%-2% sweet almond oil.
Aleurites Moluccana seed oil and coconut oil did not produce adverse effects in efficacy studies. Cashew nut oil
and macadamia nut oil caused allergic response in separate case studies.
CIR Panel Book Page 168
17
FIGURES AND TABLES
OCR
O
H2C
HC OCR'
O
H2C OCR"
O
-OCR, -OCR', and -OCR" may be the same or dif ferent fatty acid radicals.
Figure 1. General structure of fats and oils.1
CIR Panel Book Page 169
18
Figure 2. Basic oil refinement flowchart.5
Crude Oil
Degummed Oil Lecithin Sludge
Alkali Refined Oil Soap Stock
Salad Oil
Cooking Oil Salad and
Cooking Oil Partially
Hydrogenated Oil
Other Fatty Oil
Shortening Stock
Blended Oils
Margarine Stock
Bleached Oil
Salad Oil
Water
Alkali
Deodorization
Deodorization
Deodorization
Deodorization
Deodorization
Deodorization
Activated Earth
H2, Catalyst
Winterization & Deodorization
CIR Panel Book Page 170
19
Table 1. Nut oils and their derivatives.
Aleurites Moluccana Seed Oil (CAS No. 8015-80-3) [Kukui]
Aleurites Moluccanus Bakoly Seed Oil Hydrogenated Kukui Nut Oil
Anacardium Occidentale (Cashew) Seed Oil (CAS No. 8007-24-7)
Arachis Hypogaea (Peanut) Oil (CAS No. 8002-03-7)
Peanut Acid (CAS No. 91051-35-3) Potassium Peanutate
Sodium Peanutate
Bertholletia Excelsa Seed Oil [Brazil]
Butyrospermum Parkii (Shea) Oil Butyrospermum Parkii (Shea) Butter (CAS No. 68920-03-6; 194043-92-0)
Butyrospermum Parkii (Shea) Butter Unsaponifiables (CAS No. 194043-92-0; 225234-14-0)
Hydrogenated Shea Butter
Canarium Indicum Seed Oil [Galip] Carya Illinoensis (Pecan) Seed Oil
Cocos Nucifera (Coconut) Oil (CAS No. 8001-31-8)
Coconut Acid (CAS No. 61788-47-4)
Hydrogenated Coconut Acid (CAS No. 68938-15-8) Hydrogenated Coconut Oil (CAS No. 84836-98-6)
Magnesium Cocoate
Potassium Cocoate (CAS No. 61789-30-8)
Potassium Hydrogenated Cocoate Sodium Cocoate (CAS No. 61789-31-9)
Sodium Hydrogenated Cocoate
Cocos Nucifera (Coconut) Seed Butter
Corylus Americana (Hazel) Seed Oil Corylus Avellana (Hazel) Seed Oil
Hydrogenated Hazelnut Oil
Gevuina Avellana Oil [Chilean Hazel]
Juglans Regia (Walnut) Seed Oil (CAS No. 8024-09-7) Macadamia Integrifolia Seed Oil
Macadamia Ternifolia Seed Oil (CAS No. 128497-20-1 or 129811-19-4)
Hydrogenated Macadamia Seed Oil
Sodium Macadamiaseedate Pistacia Vera Seed Oil [Pistachio] (CAS No. 90082-81-8 or 129871-01-8)
Hydrogenated Pistachio Seed Oil
Plukenetia Volubilis Seed Oil [Sacha Inchi]
Prunus Amygdalus Dulcis (Sweet Almond) Oil (CAS No. 8007-69-0 or 90320-37-9) Hydrogenated Sweet Almond Oil
Hydrogenated Sweet Almond Oil Unsaponifiables
Sodium Sweet Almondate
Schinziophyton Rautanenii Kernel Oil [Mongongo]
CIR Panel Book Page 171
20
Table 2. Previously reviewed nut oils, fatty acids, and glyceryl triesters.
Ingredients Publication Date Conclusion
Oil Ingredients Arachis Hypogaea (Peanut) Oil (CAS No. 8002-03-7)
IJT 20(S2):65-77, 2001 Safe Hydrogenated Peanut Oil (CAS No. 68425-36-5)
Peanut Acid (CAS No. 91051-35-3)
Cocos Nucifera (Coconut) Oil (CAS No. 8001-31-8)
JACT 5(3):103-121, 1986; CIR Final Report, 2008 Safe
Coconut Acid (CAS No. 61788-47-4) Hydrogenated Coconut Acid (CAS No. 68938-15-8)
Hydrogenated Coconut Oil (CAS No. 84836-98-6)
Magnesium Cocoate
Potassium Cocoate (CAS No. 61789-30-8) Potassium Hydrogenated Cocoate
Sodium Cocoate (CAS No. 61789-31-9)
Sodium Hydrogenated Cocoate
Corylus Americana (Hazel) Seed Oil IJT 20 (S1):15-20, 2001 Insufficient data
Corylus Avellana (Hazel) Seed Oil
Prunus Amygdalus Dulcis (Sweet Almond) Oil (CAS No. 8007-69-0)
JACT 2(5):85-99, 1983; Re-reviewed, not reopened IJT 24 (S1):1-102, 2005 Safe
Fatty Acids
Arachidonic Acid (CAS No. 506-32-1) JACT 12 (5):481-559, 1993 Insufficient data
Hydroxystearic Acid (CAS No. 106-14-9) IJT 18(S1):1-10, 1999 Safe
Lauric Acid (CAS No. 143-07-7)
JACT 6(3):321-401, 1987; Re-reviewed, not reopened IJT 25(2):1-89, 2006
Safe Myristic Acid (CAS No. 544-63-8)
Oleic Acid (CAS No. 112-80-1)
Palmitic Acid (CAS No. 57-10-3)
Stearic Acid (CAS No. 57-11-4)
Glyceryl Triesters
Trilaurin (CAS No. 538-24-9)
IJT 20 (S4):61-94, 2001 Safe
Triarachidin (CAS No. 620-64-4)
Tribehenin (CAS No. 18641-57-1)
Tricaprin (CAS No. 621-71-6)
Tricaprylin (CAS No. 538-23-8)
Trierucin (CAS No. 2752-99-0)
Triheptanoin (CAS No. 620-67-7)
Triheptylundecanoin (CAS No. 105214-66-2)
Triisononanoin
Triisopalmitin (CAS No. 68957-79-9)
Triisostearin (CAS No. 26942-95-0)
Trilinolenin (CAS No. 14465-68-0)
Trimyristin (CAS No. 555-45-3)
Trioctanoin (CAS No. 7360-38-5)
Triolein (CAS No. 122-32-7)
Tripalmitin (CAS No. 555-44-2)
Tripalmitolein (CAS No. 20246-55-3)
Triricinolein (CAS No. 2540-54-7)
Tristearin (CAS No. 555-43-1)
Triundecanoin (CAS No. 13552-80-2)
Glyceryl Triacetyl Hydroxystearate (CAS No. 27233-00-7)
Glyceryl Triacetyl Ricinoleate (CAS No. 101-34-8) Glyceryl Stearate Diacetate
CIR Panel Book Page 172
21
Tab
le 3
. Ave
rage
che
mic
al p
rope
rtie
s fo
r cr
ude
and
refin
ed o
ils.
Ale
urite
s M
oluc
anna
See
d O
il [K
ukui
]50
-53
Ana
card
ium
O
ccid
enta
le
(Cas
hew
) S
eed
Oil54
A
rach
is H
ypog
aea
(Pea
nut)
Oil5;
50;5
5-57
Ber
thol
letia
E
xcel
sa S
eed
Oil
[Bra
zil]
54;5
8
But
yros
perm
um
Par
kii (
She
a)
But
ter5;
50;5
9;60
But
yros
perm
um
Par
kii (
She
a) O
il61
Car
ya Il
linoe
nsis
(P
ecan
) S
eed
Oil50
;54;
58
Fre
e fa
tty
aci
ds
(%)
0.1
- 4
; 2 m
ax
(ref
ined
) 0
.2-2
.08
; 0.5
ma
x 1
.0 m
ax
as
olei
c a
cid
< 0.
1 a
s ol
eic
aci
d
Tite
r (◦
C)
26-3
2 4
9-5
4
Mel
ting
poi
nt
(◦C)
32 -
45;
28
-42
(slip
)
Sol
idifi
catio
n p
oin
t (◦
C)
-15
Ref
ract
ive
ind
ex
1.4
73 -
1.4
79
(25◦
C);
1.4
70-1
.48
0 (2
0◦C
) 1.
470
-1.4
72; 1
.462
-1
.464
(4
0◦C)
1.4
73
1.4
68 (
25◦C
) 1
.472
Iod
ine
valu
e 1
.0 m
ax
1.5
ma
x
Sa
pon
ifica
tion
va
lue
146
- 1
66;
13
0-1
75
74
-107
; 80
-106
7
4.2
50
-67;
45
-73
28
- 43
1
00 -
10
5
Per
oxi
de
valu
e (m
eq
O2
/kg
oil)
190
- 1
93;
18
5-2
10
180
-208
; 185
-19
5 1
92.4
1
78-1
90; 1
65-1
90
185
-195
1
90
Sp
ecifi
c gr
avi
ty
5.0
ma
x 0
.22
0.3
9; 5
.0 m
ax
0.1
6 5
.0 m
ax
< 1
0 0
.15
Ap
pea
ran
ce
0.9
20-0
.940
(1
5.5◦C
); 0
.920
-0 .
930
(2
0◦C
)
0.9
10 -
0.9
15
(25◦
/25◦
C);
0.9
12-
0 .9
20 (
20◦
C)
0.9
14 (
25◦C
) 0
.918
(1
5◦C)
0.9
24 (
25◦C
)
CIR Panel Book Page 173
22
Tab
le 3
. Ave
rage
che
mic
al p
rope
rtie
s fo
r cr
ude
and
refin
ed n
ut o
ils (
cont
inue
d).
C
ocos
Nuc
ifier
a (C
ocon
ut)
Oil5;
50;6
1 H
azel
See
d O
il55;6
2;63
Jugl
ans
Reg
ia
(Wal
nut)
See
d O
il50;5
5;58
Mac
adam
ia N
ut
Oil55
;58;
64;6
5 P
ista
cia
Ver
a S
eed
Oil
[Pis
tach
io]54
Pru
nus
Am
ygda
lus
(Sw
eet A
lmon
d)
Oil5;
50;5
5;66
;67
Fre
e fa
tty
aci
ds
(%)
< 0
.1%
as
olei
c a
cid
; < 0
.07
% a
s la
uric
aci
d 0
.2 m
ax
as
olei
c a
cid
0.2
- 2
.5
0.5
ma
x; 1
.0 m
ax
as
olei
c a
cid
1.0
ma
x
Tite
r (◦
C)
20
- 24
M
eltin
g p
oin
t (◦C
) 2
2 -
26
Solid
ifica
tion
poi
nt
(◦C
) 9.
0 -
12.
0
Ref
ract
ive
ind
ex
1.4
48 -
1.4
50
(40◦C
) 1
.467
-1.4
74 (
20◦C
) 1
.475
(2
5◦C)
1.4
69; 1
.466
-1.4
70
(20◦
C)
1.4
62 -
1.4
66
(40◦
C);
1.4
67-1
.47
3 ( 2
0◦C
)
Iod
ine
valu
e 0
.6 m
ax
(ref
ined
) S
ap
onifi
catio
n v
alu
e 6
.0 -
11
83
-97
150
- 1
62
78.
3; 6
2-8
2 9
3 -
106
Per
oxi
de
valu
e (m
eq
O2
/kg
oil)
248
- 2
65
187
-197
1
90 -
19
7 1
93.7
; 190
-200
1
83 -
19
7; 1
85
-195
Sp
ecifi
c gr
avi
ty
< 1
0 0
.43;
10.
0 m
ax
0.3
7 0
.36;
10.
0 m
ax
0.2
2 0
.19
Ap
pea
ran
ce
0.9
17 -
0.9
19
(25◦
/15.
5◦C
) 0.
912
-0.9
17
(15
.5◦C
) 0
.917
(2
5◦C)
0.9
15 (
25◦
C);
0.
911
-0.9
18 (
20◦C
)
0.9
13 -
0.9
16
(25◦
C);
0.9
11-0
.92
0 (2
0◦C
)
CIR Panel Book Page 174
23
Tab
le 4
. Ave
rage
che
mic
al c
onst
ituen
ts fo
r cr
ude
and
refin
ed o
ils.
Ale
urite
s M
oluc
anna
See
d O
il [K
ukui
]50
-53
Ana
card
ium
O
ccid
enta
le
(Cas
hew
) S
eed
Oil54
A
rach
is H
ypog
aea
(Pea
nut)
Oil5;
50;5
5-57
Ber
thol
letia
E
xcel
sa S
eed
Oil
[Bra
zil]
54;5
8
But
yros
perm
um
Par
kii (
She
a)
But
ter5;
50;5
9;60
But
yros
perm
um
Par
kii (
She
a) O
il61
Car
ya Il
linoe
nsis
(P
ecan
) S
eed
Oil50
;54;
58
Un
sap
onifi
able
m
atte
rs (
%)
0.3
- 1
; 1.0
ma
x <
1.0
3
.0 -
10.
0 <
1.5
0
.35
- 40
α-T
ocoh
ph
erol
(m
g/g)
3
.6
0.0
879
82.
9 1
2.2
γ-T
ocop
her
ol
(mg/
g)
57.
2 0
.060
3 1
16.2
1
68.5
Sq
uale
ne
(mg/
g)
89.
4 0
.098
3 1
377
.8
151
.7
β-S
itost
erol
(m
g/g)
1
768
1.3
6 1
325
.4
1572
.4
Ca
mp
este
rol (
mg/
g)
105
.3
0.1
98
26.
9 5
2.2
Stig
ma
ster
ol
116
.7
0.1
63
577
.5
340
.4
C
ocos
Nuc
ifier
a (C
ocon
ut)
Oil5;
50;6
1 H
azel
See
d O
il55;6
2;63
Jugl
ans
Reg
ia
(Wal
nut)
See
d O
il50;5
5;58
Mac
adam
ia N
ut
Oil55
;58;
64;6
5 P
ista
cia
Ver
a S
eed
Oil
[Pis
tach
io]54
Pru
nus
Am
ygda
lus
(Sw
eet A
lmon
d)
Oil5;
50;5
5;66
;67
Un
sap
onifi
able
m
atte
rs (
%)
< 0
.5
0.5
0
.4 -
1.0
α-T
ocoh
ph
erol
(m
g/g)
0
.31
0.0
21
0.1
22
15.
6 0
.439
5
γ-T
ocop
her
ol
(mg/
g)
0.0
612
0.3
01
Tra
ce
275
.4
0.0
125
Sq
uale
ne
(mg/
g)
0.1
86
0.0
094
0.1
85
91.
4 0
.095
β-S
itost
erol
(m
g/g)
0
.991
1
.13
1.5
1 4
685
.9
2.0
7
Ca
mp
este
rol (
mg/
g)
0.0
667
0.0
51
0.0
733
236
.8
0.0
55
Stig
ma
ster
ol
0.0
381
0.0
555
0.0
383
663
.3
0.0
517
CIR Panel Book Page 175
24
T
able
5. F
atty
aci
d co
mpo
sitio
n.
Fat
ty A
cids
C
ocos
Nuc
ifier
a (C
ocon
ut)
Oil15
A
rach
is H
ypog
aea
(Pea
nut)
Oil5;
56;5
7 B
utyr
ospe
rmum
P
arki
i (S
hea)
Oil61
But
yros
perm
um
Par
kii (
She
a)
But
ter5;
59;6
0
Jugl
ans
Reg
ia
(Wal
nut)
See
d O
il68
Mac
adam
ia N
ut
Oil2;
64;6
5
Pru
nus
Am
ygda
lus
(Sw
eet A
lmon
d)
Oil5;
50;6
6;67
;69
Cap
roic
(C
6)
0-1
Cap
rylic
(C
8)
5-9
Cap
ric (
C1
0)
6-1
0 La
uric
(C
12)
44
-52
0.1
- 1
.4
Myr
istic
(C
14)
13
-19
0.7
- 0
.8
1
(C15
)
Pa
lmiti
c (C
16)
8-1
1 7
.2-1
4.2
; 7.0
-16.
0 3
.8-4
.1
5.0
-9.0
; 3.0
-9.0
3
.0 -
7
8.0
- 9
.2; 6
.0-1
2.0
5.5
-6.5
; 6
Pa
lmito
leic
(C
16
:1)
0-1
1
5.6
- 24
.6; 1
2-2
5 H
epta
dec
an
oic
(C17
)
(C17
:1)
Ste
aric
(C
18)
1-3
1
.1-5
; 1.3
-6.5
4
1.2
-56.
8 3
0-4
1; 3
4.0
-50
.0
0.5
- 3
3
.3 -
3.4
; 0.5
-8
2.0
-3.0
Ole
ic (
C18
:1)
5-8
3
3.3
-71.
2; 3
5.0
-72
.0
34.
0-4
6.9
45
-50;
38
.0-5
0.0
9
.0 -
30
54.
8 -
64.2
; 50
-67
70
-77;
69
Lin
olei
c (C
18:2
) T
race
- 2
.5
12
-47.
5; 1
3.0
-43
.0
3.7
-6.5
4
.0-5
; 3.0
-8.0
5
7 -
76
1.5
-5
17
- 20
Li
nol
enic
(C
18
:3)
0
-0.0
4; 0
.6
0.5
ma
x 2
.0 -
16
1.5
- 1
.9; 0
.5 m
ax
0.4
Ara
chid
ic (
C20
)
0.1
7-2
.7; 0
.5-3
.0
1.0
-2.0
3
2.4
- 2
.7; 1
.5-5
Eic
osen
oic
(C2
0:1
)
0.3
3-2
.3; 0
.5-2
.1
2.1
- 3
.1; 1
.5-3
E
icos
adie
noi
c (C
20:2
)
Beh
enic
(C
22)
0
.7-4
.1; 1
.0-5
.0
0.3
- 0
.7
Eru
cic
(C22
:1)
0
.5
(C23
)
Lign
ocer
ic (
C2
4)
0
.2-2
.8; 0
.5-3
.0
*Sh
ad
owin
g id
entif
ies
pre
viou
sly
revi
ew
ed in
gred
ien
ts.
CIR Panel Book Page 176
25
T
able
5. F
atty
aci
d co
mpo
sitio
n (c
ontin
ued)
.
Fat
ty A
cids
Car
ya Il
linoe
nsis
(P
ecan
) S
eed
Oil50
;54
Ale
urite
s M
oluc
anna
See
d O
il [K
ukui
]50
;52;
53
Cor
ylus
Ave
llana
(H
azel
) S
eed
Oil9;
62;6
3
Ber
thol
letia
E
xcel
sa S
eed
Oil
[Bra
zil]
54
Pis
taci
a V
era
See
d O
il [P
ista
chio
]54
Ana
card
ium
O
ccid
enta
le
(Cas
hew
) S
eed
Oil54
Cap
roic
(C
6)
Cap
rylic
(C
8)
Cap
ric (
C1
0)
Lau
ric (
C12
)
Myr
istic
(C
14)
Tra
ce
0.0
3 -
0.04
0
.06
0.0
9 0
.07
(C15
)
0.0
1
Pa
lmiti
c (C
16)
3 -
4.3
5
.5; 5
-8
4.9
6 -
5.8;
5-9
1
3.5
7.4
9
.9
Pa
lmito
leic
(C
16
:1)
0.1
0
.5
0.2
; 0.5
-1.0
0
.3
0.7
0
.4
Hep
tad
eca
noi
c (C
17)
0.1
0
.04
- 0.
05
0.2
0
.1
(C17
:1)
0.0
7 -
0.08
Ste
aric
(C
18)
1.8
- 2
6
.7; 0
.1-5
1
.7 -
1.9
; 1.0
-6.0
1
1.8
0.9
8
.7
Ole
ic (
C18
:1)
40.
6 -
79
10.
5; 1
0-3
5 8
0.7
- 82
.6; 6
6-8
5 2
9.1
58.
2 5
7.2
Lin
olei
c (C
18:2
) 1
6 -
50.3
4
8.5;
35
-50
9.8
- 1
1.3;
7-2
5 4
2.8
30.
3 2
0.8
Lin
olen
ic (
C1
8:3
) 0
.7
28.
5; 2
4-4
0 0
.2; 0
.5-0
.6
0.2
0
.4
0.2
Ara
chid
ic (
C20
) T
race
1
.5
0.1
0
.5
0.6
1
Eic
osen
oic
(C2
0:1
) 1
.2
1.0
0
.1 -
0.2
0
.2
0.6
0
.3
Eic
osad
ien
oic
(C20
:2)
Beh
enic
(C
22)
0.2
0
.02
0.1
0
.3
0.4
Eru
cic
(C22
:1)
0.3
0
.01
0.3
0
.6
0.3
(C23
) 0
.01
Lign
ocer
ic (
C2
4)
0
.01
*Sh
ad
owin
g id
entif
ies
pre
viou
sly
revi
ew
ed in
gred
ien
ts.
CIR Panel Book Page 177
26
T
able
6.
Fre
quen
cy a
nd c
once
ntra
tion
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
.14
;15;
26-2
9
No.
of
Use
s C
onc.
of
Use
(%)
No.
of
Use
s C
onc.
of
Use
(%)
No.
of
Use
s C
onc.
of
Use
(%)
No.
of
Use
s C
onc.
of
Use
(%)
No.
of
Use
s C
onc.
of
Use
(%)
S
wee
t Alm
ond
Oil
Hyd
rog.
Sw
eet A
lmon
d O
il S
odiu
m S
wee
t Alm
onda
te
Cas
hew
Oil
Haz
el N
ut O
il (C
. Am
eric
ana)
Fre
quen
cy o
f Use
11
27
0.00
4 -
76
21
4
10
10
Le
ave
-On
801
0
.004
- 7
6 1
3
4
9
9
Rin
se O
ff
326
0
.01
- 2
8
0
1
1
Eye
2
8 0
.4
0 0
0 0
Pos
sib
le In
gest
ion
5
5 0
.5
1 0
0 0
Inh
ala
tion
18
1 -
3
0 0
0 0
Der
ma
l 9
86
0.0
04 -
11
15
4 9
10
Deo
dor
an
t (u
nder
arm
) 2
0.0
04
0 0
0 0
Ha
ir -
Non
-co
lorin
g 1
17
0.3
- 3
6
0 1
0
Ha
ir -
Col
orin
g 2
0.1
0
0 0
0 N
ail
13
1 -
76
0 0
0 0
Muc
ous
Mem
bra
ne
134
0
.01
- 0.
1 2
0 0
1
Bab
y 1
8 -
0 0
0 0
(2
002
con
c.)
H
azel
Nut
Oil
(C. A
vella
na)
Mac
adam
ia In
tegr
ifolia
Nut
Oil
Mac
adam
ia N
ut O
il M
acad
amia
Ter
nifo
lia N
ut O
il S
chin
ziop
hyto
n R
auta
neni
i K
erne
l Oil
Fre
quen
cy o
f Use
15
0 up
to 1
00
41
20
8
533
6
Le
ave
-On
130
25
1
91
4
71
3
R
inse
Off
20
1
6
17
6
2
3
Eye
9
4 2
2 1
6 0
Pos
sib
le In
gest
ion
2
4 1
1 3
3 0
Inh
ala
tion
0 0
2 1
2 0
Der
ma
l 1
47
36
170
4
93
3 D
eod
ora
nt
(und
era
rm)
0 0
0 0
0
Ha
ir -
Non
-co
lorin
g 2
2 9
33
3
Ha
ir -
Col
orin
g 0
0 0
3 0
Na
il 1
0 2
8 1
0 M
ucou
s M
emb
ran
e 3
11
1 1
4 0
Bab
y 1
0 0
4 0
(200
1 co
nc.
)
CIR Panel Book Page 178
27
T
able
6.
Fre
quen
cy a
nd c
once
ntra
tion
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
(co
ntin
ued)
.14
;15;
26-2
9
No.
of
Use
s C
onc.
of
Use
(%
) N
o. o
f U
ses
Con
c. o
f U
se (%
) N
o. o
f U
ses
Con
c. o
f U
se (%
) N
o. o
f U
ses
Con
c. o
f U
se(%
) N
o. o
f U
ses
Con
c. o
f U
se (%
)
P
ecan
Nut
Oil
Pis
tach
io N
ut O
il P
luke
netia
Vol
ubili
s S
eed
Oil
Wal
nut O
il C
ocon
ut O
il
Fre
quen
cy o
f Use
8
15
8
13
15
798
0.00
01 -
80
Le
ave
-On
7
105
12
1
2
372
0
.005
- 8
0
Rin
se O
ff
1
53
1
3
4
26
0.0
001
- 4
1
Eye
1
7 1
1 2
5 0
.01
- 80
P
ossi
ble
Inge
stio
n
0 6
3 0
44
0.2
- 5
1 In
ha
latio
n 0
0 0
0 1
0 0
.1 -
26
Der
ma
l 8
133
1
3 1
4 5
48
0.0
005
- 8
0 D
eod
ora
nt
(und
era
rm)
0 0
0 0
0 0
.1 -
16
Ha
ir -
Non
-co
lorin
g 0
18
0 1
176
0
.000
1 -
13
Ha
ir -
Col
orin
g 0
0 0
0 6
9 -
Na
il 0
2 0
0 5
0.0
05 -
2
Muc
ous
Mem
bra
ne
1 2
7 0
2 1
76
0.0
005
- 4
1 B
aby
0 3
0 0
15
0.0
1 -
0.3
(200
8 co
nc.
)
H
ydro
g. C
ocon
ut O
il C
ocon
ut A
cid
Hyd
rog.
Coc
onut
Aci
d
Mag
nesi
um C
ocoa
te
Pot
assi
um C
ocoa
te
Fre
quen
cy o
f Use
10
5 0.
001
- 50
14
1 0.
03 -
14
0 6
- 10
9
- 40
0.
003
- 40
Le
ave
-On
79
0.0
01 -
50
17
- 0
6 0
- 0
0.3
Rin
se O
ff
26
0.0
01 -
39
124
0
.03
- 14
0
10
9 -
40
0.0
03 -
40
Eye
7
0.2
- 2
2 1
- 0
- 0
- 0
- P
ossi
ble
Inge
stio
n
10
0.7
- 2
9 0
- 0
- 0
- 0
- In
ha
latio
n 0
0.3
- 0
.7
0 -
0 -
0 -
0 -
Der
ma
l 1
02
0.0
6 -
50
140
0
.04
- 14
0
6 -
10
9 -
38
0.3
- 4
0 D
eod
ora
nt
(und
era
rm)
0 -
0 -
0 -
0 -
0 0
.3
Ha
ir -
Non
-co
lorin
g 3
0.0
01 -
2
1 0
.03
- 0.
3 0
- 0
- 2
15
Ha
ir -
Col
orin
g 0
0.5
- 0
.6
0 -
0 -
0 -
0 0
.003
N
ail
0 0
.8 -
25
0 -
0 -
0 -
0 -
Muc
ous
Mem
bra
ne
18
0.5
- 3
9 1
01
0.0
4 -
14
0 -
9 -
26
0.2
- 4
0 B
aby
1 2
- 5
0 1
- 0
- 0
- 0
-
(200
8 co
nc.
)
(200
8 co
nc.
)
(200
8 co
nc.
)
(200
8 co
nc.
)
(200
8 co
nc.
)
CIR Panel Book Page 179
28
T
able
6.
Fre
quen
cy a
nd c
once
ntra
tion
of u
se a
ccor
ding
to d
urat
ion
and
expo
sure
(co
ntin
ued)
.14
;15;
26-2
9
No.
of
Use
s C
onc.
of
Use
(%
) N
o. o
f U
ses
Con
c. o
f U
se
(%)
No.
of
Use
s C
onc.
of
Use
(%
) N
o. o
f U
ses
Con
c. o
f U
se
(%)
No.
of
Use
s C
onc.
of
Use
(%
)
Sod
ium
Coc
oate
P
eanu
t Oil
Hyd
rog.
Pea
nut O
il S
hea
But
ter
She
a B
utte
r O
il
Fre
quen
cy o
f Use
34
0 1
- 52
74
<2
5 -
>50
12
1950
0.
0005
– 6
0 22
0.
01 –
15
Le
ave
-On
12
- 5
3
12
1
596
0.0
01 -
60
16
0.0
1 –
15
Rin
se O
ff
328
1
- 5
2 2
1
0
354
0
.000
5 -
30
6 0
.6 –
1
Eye
0
- 4
0 1
08
0.1
- 8
1
- P
ossi
ble
Inge
stio
n
0 -
0 0
128
0
.5 -
26
0 1
5 In
ha
latio
n 0
- 2
0 1
7 0
.001
- 3
0
- D
erm
al
269
1
- 5
2 5
3 1
2 1
724
0.0
01 -
45
22
0.6
– 1
5 D
eod
ora
nt
(und
era
rm)
0 -
0 0
2 1
0 -
Ha
ir -
Non
-col
orin
g 7
1 2
21
0 2
10
0.0
005
- 5
0
-
Ha
ir -
Col
orin
g 0
- 0
0 4
- 0
- N
ail
0 -
0 0
7 0
.01
- 60
0
0.0
1 –
1 M
ucou
s M
emb
ran
e 2
41
1 -
52
2 0
114
0
.003
- 5
6
0.6
– 1
B
aby
5 -
0 0
24
0.0
1 -
5 0
-
(200
8 co
nc.
)
(200
1 co
nc.
)
2
010
con
c.
2
010
con
c.
H
ydro
g. S
hea
But
ter
She
a B
utte
r U
nsap
on.
Ale
urite
s S
eed
Oil
Ber
thol
letia
Exc
elsa
Oil
Gev
uina
Ave
llana
Oil
Fre
quen
cy o
f Use
4
1 38
0.
06 –
3
141
55
5 Le
ave
-On
2 1
33
0.0
6 –
3 8
7
18
5
Rin
se O
ff
2 1
5 2
54
3
7
0 E
ye
0 -
7 0
.2 –
0.7
6
1 0
Pos
sib
le In
gest
ion
0
- 2
1 –
3
1 0
0 In
ha
latio
n 0
- 0
- 1
5 1
0 D
erm
al
4 1
33
0.0
6 –
3 7
6 2
9 5
Deo
dor
an
t (u
nder
arm
) 0
- 0
- 0
0 0
Ha
ir -
Non
-col
orin
g 0
- 5
2 5
8 1
2 0
Ha
ir -
Col
orin
g 0
- 0
- 0
14
0 N
ail
0 -
0 -
4 0
0 M
ucou
s M
emb
ran
e 2
- 0
- 1
1 1
0 0
Bab
y 0
- 1
- 0
0 0
201
0 c
onc.
201
0 c
onc.
CIR Panel Book Page 180
29
Table 7. Non-food, non-cosmetic uses of edible oils.5;51;68-72
Oil Use
Almond Pharmaceutical, energy source
Cashew Folk remedies
Coconut Lubricants, hydraulic fluid, paints, synthetic rubber, plastics, illumination
Kukui Wood preservative, varnishes, paint oil, illumination, soap making, waterproofing paper, rubber substitute, insulating material
Peanut Pharmaceutical, soap making, lubricants, emulsions for insect control, diesel engine fuel
Shea Illumination
Walnut Paints, soap making
CIR Panel Book Page 181
30
Reference List
(1) Gottschalck TE, Bailey JE. International Cosmetic Ingredient Dictionary and Handbook. 13th. 2010. Washington, DC, Personal Care Products Council.
Ref Type: Edited Book
(2) Center for New Crops & Plant Products. Macadamia integrifolia Maiden & Betche and Macadamia tetraphylla L. Johnson. NewCROP . 1-7-1998. Department of Horticulture and Landscape Architecture, 625 Agriculture Mall Drive, West Lafayette, IN 47907-2010, Purdue University. 5-20-2010.
Ref Type: Online Source
(3) Storey W. The Ternifolia group of Macadamia species. Pacific Science 1965;19:507-514.
(4) Miraliakbari H, Shahidi F. Oxidative stability of tree nut oils. J Agric Food Chem 2008;56:4751-4759.
(5) Salunkhe D, Chavan J, Adsule R, Kadam S. World Oilseeds: Chemistry, Technology, and Utilization. New York: Van Nostrand Reinhold, 1992.
(6) Loden M, Andersson A. Effect of topically applied lipids on surfactant-irritated skin. Br J Dermatol 1996;134:215-220.
(7) Bailey's Industrial Oil & Fat Products. John Wiley & Sons., 1996.
(8) Davrieux F, Allal F, Piombo G et al. Near infrared spectroscopy for high-throughput characaterization shea tree (Vitellaria paradoxa) nut fat profiles. J Agric Food Chem 2010.
(9) Oliveira I, Sousa A, Morais J et al. Chemical composition, and antioxidant and antimicrobial activities of three hazelnut (Corylus avellana L.) cultivars. Food Chem Toxicol 2008;46:1801-1807.
(10) Holcapek M, Jandera P, Zderadicka P, Hruba L. Characterization of triacylglycerol and diacylglycerol composition of plant oils using high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. J Chromatogr A 2003;1010:195-215.
(11) Saraiva S, Cabral E, Eberlin M, Catharino R. Amazonian vegetable oils and fats: Fast typification and quality control via triacylglycerol (TAG) profiles from dry matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry fingerprinting. J Agric Food Chem 2009;57:4030-4034.
(12) Crevel RW, Kerkhoff MA, Koning MM. Allergenicity of refined vegetable oils. Food Chem Toxicol 2000;38:385-393.
(13) Teuber S, Brown R, Haapanen L. Allergenicity of gourmet nut oils processed by different methods. J Allergy Clin Immunol 1997;99:502-507.
(14) Andersen,F.A.(ed). Final report on the safety assessment of peanut (arachis hypogaea) oil, hydrogenated peanut oil, peanut acid, peanut glycerides, and peanut (arachis hypogaea) flour. Int J Toxicol 2001;20:65-77.
(15) Burnett C, Cosmetic Ingredient Review Expert Panel, Andersen F. Final Report of the Cosmetic Ingredient Review Expert Panel. Amended Safety Assessment of Cocos Nucifera (Coconut) Oil, Coconut Acid, Hydrogenated Coconut Oil, Ammonium Cocomonoglyceride Sulfate, Butylene Glycol Cocoate, Caprylic/Capric/Coco Glycerides, Cocoglycerides, Coconut Alcohol, Coconut Oil Decyl Esters, Decyl Cocoate, Ethylhexyl Cocoate, Hydrogenated Coco-Glycerides, Isodecyl Cocoate, Lauryl Cocoate, Magnesium Cocoate, Methyl Cocoate, Octyldodecyl Cocoate, Pentaerythrityl Cocoate, Potassium Cocoate, Potassium Hydrogenated Cocoate, Sodium Cocoate, Sodium Cocomonoglyceride Sulfate, Sodium Hydrogenated Cocoate, and Tridecyl Cocoate. Available from CIR 2008.
(16) Olszewski A, Pons L, Moutété F et al. Isolation and characterization of proteic allergens in refined peanut oil. Clin Exp Allergy 1998;28:850-859.
CIR Panel Book Page 182
31
(17) Ramazzotti M, Mulinacci N, Pazzagli L et al. Analytic investigations on protein content in refined seed oils: implications in food allergy. Food Chem Toxicol 2008;46:3383-3388.
(18) European Medicines Agency (EMEA). Working party on herbal medicinal products. Final position paper on the allergenic potency of herbal medicinal products containing soya or peanut protein. EMEA/HMPWP/37/04. http://www ema europa eu/pdfs/human/hmpc/003704en pdf [serial online] 2004; Accessed April 12, 10 A.D.
(19) Pease RW. Webster's Medical Desk Dictionary. 1986. Springfield, MA, Merriam-Webster, Inc. Ref Type: Edited Book
(20) Budavari S. The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals. 10th. 1989. Rahway, NJ, Merck and Co.
Ref Type: Edited Book
(21) Wood GE. Aflatoxins in domestic and imported foods and feeds. J Assoc Anal Chem 1989;72:543-548.
(22) IARC. IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. [10], 51-72. 1976. Lyon, France, IARC.
Ref Type: Serial (Book,Monograph)
(23) IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. Overall evaluations of carcinogenicity: An updating of IARC Monographs volumes 1 to 42. [Supplement 7], 83-87. 1987. Lyon, France, IARC.
Ref Type: Serial (Book,Monograph)
(24) Wilson DM. Analytical methods for aflatoxins in corn and peanuts. Arch Environ Contam Toxicol 1989;18:308-314.
(25) Food and Drug Administration (FDA). CPG Sec. 555.400 Foods - Adulteration with Alfatoxin. 12-9-2009. 6-21-2010.
Ref Type: Online Source
(26) Andersen F. Final Report on the Safety Assessment of Corylus Avellana (Hazel) Seed Oil, Corylus Americana (Hazel) Seed Oil, Corylus Avellana (Hazel) Seed Extract, Corylus Americana (Hazel) Seed Extract, Corylus Rostrata (Hazel) Seed Extract, Corylus Avellana (Hazel) Leaf Extract, Corylus Americana (Hazel) Leaf Extract, and Corylus Rostrata (Hazel) Leaf Extract. IJT 2001;20:15-20.
(27) Food and Drug Administration (FDA). Frequency of use of cosmetic ingredients. FDA database 2010.
(28) Personal Care Products Council. Updated Concentration of Use - Butyrospermum Parkii (Shea) Butter, et al. Unpublished data. 7-26-2010.
Ref Type: Generic
(29) Andersen F. Annual Review of Cosmetic Ingredient Safety Assessments - 2002/2003. IJT 2005;24:1-102.
(30) James AC, Stahlhofen W, Rudolf G et al. Annexe D. Deposition of inhaled particles. Annals of the ICRP 1994;24:231-2.
(31) Oberdorster G, Oberdorster E, Oberdorster J. Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles. Environmental Health Perspectives 2005;113:823-839.
(32) Bower D. Unpublished information on hair spray particle sizes provided at the September 9, 1999 CIR Expert Panel meeting. 1999.
(33) Johnson MA. The Influence of Particle Size. Spray Technology and Marketing 2004;November:24-27.
(34) 1976, Council Directive 1976/768/EEC of 27 July 1976 on the Approximation of the Laws of the Member States Relating to Cosmetic Products, as amended through Commission Directive 2008/42/EC.: 2008.
CIR Panel Book Page 183
32
(35) American Soybean Association. Soy Stats 2010 - World Vegetable Oil Consumption 2009. 2010. 4-14-2010. Ref Type: Online Source
(36) Elder R. Final Report on the Safety Assessment of Sweet Almond Oil and Almond Meal. JACT 1983;2:85-99.
(37) Said T, Dutot M, Christon R et al. Benefits and side effects of different vegetable oil vectors on apoptosis, oxidative stress, and P2X7 cell death receptor activation. Invest Ophthalmol Vis Sci 2007;48:5000-5006.
(38) Said T, Dutot M, Labbe A, Warnet J-M, Rat P. Ocular burn: Rinsing and healing with ionic marine solutions and vegetable oils. Ophthalmologica 2009;223:52-59.
(39) IARC. Glycidol. IARC Monographs[77], 469-486. 2000. 4-20-2010. Ref Type: Serial (Book,Monograph)
(40) IARC. Epoxides. IARC Monographs[11], 125-209. 1976. 4-20-2010. Ref Type: Serial (Book,Monograph)
(41) Federal Institute for Risk Assessment. Initial evaluation ofhte assessment of levels of glycidol fatty acid esters detected in refined vegetable fats--B&R opinion no. 007/2009. 2009. 3-10-2009.
Ref Type: Report
(42) Weisshauer R. Fatty acid esters of 3-MCPD: overview of occurences in different types of foods. 2009. Chemisches und Veterinaruntersuchungsaut (CUUA).
Ref Type: Report
(43) Singh B, Kale R, Rao A. Modulation of antioxidant potential in liver of mice by kernel oil of cashew nut (Anacardium occidentale) and its lack of tumour promoting ability in DMBA induced skin papillomagenesis. Indian J Exp Biol 2004;42:373-377.
(44) de Groot AC. Adverse Reactions to Cosmetics. Port Washington, NY: Scholium International, Inc, 1988.
(45) Yunginger J, Calobrisi S. Investigation of the allergenicity of a refined peanut oil-containing topical dermatologic agent in persons who are sensitive to peanuts. Cutis 2001;68:153-155.
(46) Consumer Product Testing Co. Repeated insult patch test of a lipstick containing 0.509847% Plukentia Volubilis Seed Oil. Experiment reference number: C08-5394.06. Unpublished data. 2008. Consumer Product Testing Co.
Ref Type: Generic
(47) Brown A, Koett J, Johnson D et al. Effectiveness of kukui nut oil as a topical treatment for psoriasis. Int J Toxicol 2005;44:684-687.
(48) Hirao A, Oiso N, Matsuda H, Kawara S, Kawada A. Occupational allergic contact dermatitis due to cashew nut oil. Contact Dermatitis 2008;59:131-132.
(49) Sugiura K, Sugiura M. Di-isostearyl malate and macademia nut oil in lipstick caused cheilitis. J Eur Acad Dermatol Venereol 2009;23:606-607.
(50) Swern, D (ed). Bailey's Industrial Oil and Fat Products. 4th ed. John Wiley & Sons, Inc., 1979.
(51) Center for New Crops & Plant Products. Aleurites moluccana (L.) Willd. NewCROP . 1997. Department of Horticulture and Landscape Architecture, 625 Agriculture Mall Drive, West Lafayette, IN 47907-2010, Purdue University. 5-20-2010.
Ref Type: Online Source
(52) John L. Seaton & Co., Ltd. Seatons Kukui Nut Oil. 2006. John L. Seaton & Co. Limited. Ref Type: Generic
(53) John L. Seaton & Co., Ltd. Seatons Refined Kukui Nut Oil Specification. 2006. John L. Seaton & Co. Limited.
CIR Panel Book Page 184
33
Ref Type: Generic
(54) Ryan E, Galvin K, O'Connor T, Maguire A, O'Brien N. Fatty acid profile, tocopherol, squalene and phytosterol content of brazil, pecan, pine, pistachio and cashew nuts. Int J Food Sci Nutr 2006;57:219-228.
(55) Maguire L, O'Sullivan S, Galvin K, O'Connor T, O'Brien N. Fatty acid profile, tocopherol, squalene and phytosterol content of walnuts, almonds, peanuts, hazelnuts and the macadamia nut. Int J Food Sci Nutr 2004;55:171-178.
(56) John L. Seaton & Co., Ltd. Arachis Oil BP/EP Specification. 2010. John L. Seaton & Co. Limited. Ref Type: Generic
(57) John L. Seaton & Co., Ltd. Seatons Arachis Oil. 2005. John L. Season & Co.Limited. Ref Type: Generic
(58) Moodley R, Kindness A, Jonnalagadda S. Elemental composition and chemical characteristics of five edible nuts (almond, Brazil, pecan, macadamia and walnut) consumed in Southern Africa. J Environ Sci Health B 2007;42:585-591.
(59) John L. Seaton & Co., Ltd. Seatons Refined Shea Nut Butter Specification. 2009. John L. Seaton & Co. Limited. Ref Type: Generic
(60) John L. Seaton & Co., Ltd. Seatons Shea Nut Butter. 2005. John L. Seaton & Co., Limited. Ref Type: Generic
(61) US Pharmacopeia. 2008-2009 Food Chemicals Codex. 6th ed. Baltimore: United Book Press, Inc., 2008.
(62) John L. Seaton & Co., Ltd. Seatons Hazelnut Oil. 2005. John L. Seaton & Co. Limited. Ref Type: Generic
(63) John L. Seaton & Co., Ltd. Seatons Refined Hazelnut Oil Specification. 2010. John L. Seaton & Co. Limited. Ref Type: Generic
(64) John L. Seaton & Co., Ltd. Seatons Macadamia Nut Oil. 2005. John L. Seaton & Co. Limited. Ref Type: Generic
(65) John L. Seaton & Co., Ltd. Seatons Refined Macadamia Nut Oil Specification. 2010. John L. Seaton & Co. Limited.
Ref Type: Generic
(66) John L. Seaton & Co., Ltd. Seatons Refined Sweet Almond Oil Cosmetic Blend Specification. 2009. John L. Seaton & Co. Limited.
Ref Type: Generic
(67) John L. Seaton & Co., Ltd. Seatons Sweet Almond Oil. 2005. John L. Seaton & Co. Limited. Ref Type: Generic
(68) Center for New Crops & Plant Products. Juglans regia L. NewCROP . 1-7-1998. Department of Horticulture and Landscape Architecture, 625 Agriculture Mall Drive, West Lafayette, IN 47907-2010, Purdue University. 5-20-2010.
Ref Type: Online Source
(69) Center for New Crops & Plant Products. Prunus dulcis (Mill.) D.A. Webb. NewCROP . 1998. Department of Horticulture and Landscape Architecture, 625 Agriculture Mall Drive, West Lafayette, IN 47907-2010, Purdue University. 5-20-2010.
Ref Type: Online Source
CIR Panel Book Page 185
34
(70) Center for New Crops & Plant Products. Anacardium occidentale L. NewCROP . 12-22-1997. Department of Horticulture and Landscape Architecture, 625 Agriculture Mall Drive, West Lafayette, IN 47907-2010, Purdue University. 5-20-2010.
Ref Type: Online Source
(71) Center for New Crops & Plant Products. Arachis hypogaea L. NewCROP . 1997. Department of Horticulture and Landscape Architecture, 625 Agriculture Mall Drive, West Lafayette, IN 47907-2010, Purdue University. 5-20-2010.
Ref Type: Online Source
(72) Center for New Crops & Plant Products. Cocos nucifera L. NewCROP . 1996. Department of Horticulture and Landscape Architecture, 625 Agriculture Mall Drive, West Lafayette, IN 47907-2010, Purdue University. 5-20-2010.
Ref Type: Online Source
CIR Panel Book Page 186
Data
CIR Panel Book Page 187
2010 FDA Frequency of Use Raw Data
01A - Baby Shampoos PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
01B - Baby Lotions, Oils, Powders, and Creams PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 13
01C - Other Baby Products PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 4
02A - Bath Oils, Tablets, and Salts PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 25
02B - Bubble Baths PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 10
02D - Other Bath Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 6
03A - Eyebrow Pencil PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
03B - Eyeliner PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2
03C - Eye Shadow PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
03D - Eye Lotion PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 5
03E - Eye Makeup Remover PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 3
03F - Mascara PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 9
03G - Other Eye Makeup Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 7
04C - Powders (dusting and talcum, excluding aftershave talc) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2
04E - Other Fragrance Preparation PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 4
05A - Hair Conditioner PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 40
05B - Hair Spray (aerosol fixatives) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 8
05F - Shampoos (non-coloring) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 27
05G - Tonics, Dressings, and Other Hair Grooming Aids PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 29
05I - Other Hair Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 12
06G - Hair Bleaches PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2
07B - Face Powders PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
07C - Foundations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 3
07E - Lipstick PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 55
07F - Makeup Bases PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
07I - Other Makeup Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 9
08B - Cuticle Softeners PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 9
08C - Nail Creams and Lotions PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
08F - Nail Polish and Enamel Removers PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
08G - Other Manicuring Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2
10A - Bath Soaps and Detergents PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 64
10B - Deodorants (underarm) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2
10E - Other Personal Cleanliness Products PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 29
11A - Aftershave Lotion PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 5
11D - Preshave Lotions (all types) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
11E - Shaving Cream PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 7
11F - Shaving Soap PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
11G - Other Shaving Preparation Products PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 3
12A - Cleansing PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 59
12B - Depilatories PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 11
12C - Face and Neck (exc shave) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 45
12D - Body and Hand (exc shave) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 200
12E - Foot Powders and Sprays PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 4
12F - Moisturizing PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 266
12G - Night PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 22
12H - Paste Masks (mud packs) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 25
12I - Skin Fresheners PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 7
12J - Other Skin Care Preps PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 72
13A - Suntan Gels, Creams, and Liquids PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 5
13B - Indoor Tanning Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 5
13C - Other Suntan Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1
CIR Panel Book Page 188
2010 FDA Frequency of Use Raw Data
02A - Bath Oils, Tablets, and Salts BITTER ALMOND OIL 2
05A - Hair Conditioner BITTER ALMOND OIL 8
05F - Shampoos (non-coloring) BITTER ALMOND OIL 5
05I - Other Hair Preparations BITTER ALMOND OIL 1
10A - Bath Soaps and Detergents BITTER ALMOND OIL 2
12A - Cleansing BITTER ALMOND OIL 1
12D - Body and Hand (exc shave) BITTER ALMOND OIL 3
12F - Moisturizing BITTER ALMOND OIL 4
12G - Night BITTER ALMOND OIL 1
12I - Skin Fresheners BITTER ALMOND OIL 1
12J - Other Skin Care Preps BITTER ALMOND OIL 3
02A - Bath Oils, Tablets, and Salts HYDROGENATED SWEET ALMOND OIL 1
05A - Hair Conditioner HYDROGENATED SWEET ALMOND OIL 1
05F - Shampoos (non-coloring) HYDROGENATED SWEET ALMOND OIL 3
05G - Tonics, Dressings, and Other Hair Grooming Aids HYDROGENATED SWEET ALMOND OIL 2
07E - Lipstick HYDROGENATED SWEET ALMOND OIL 1
10A - Bath Soaps and Detergents HYDROGENATED SWEET ALMOND OIL 1
11F - Shaving Soap HYDROGENATED SWEET ALMOND OIL 1
12C - Face and Neck (exc shave) HYDROGENATED SWEET ALMOND OIL 1
12D - Body and Hand (exc shave) HYDROGENATED SWEET ALMOND OIL 2
12F - Moisturizing HYDROGENATED SWEET ALMOND OIL 7
12H - Paste Masks (mud packs) HYDROGENATED SWEET ALMOND OIL 1
12J - Other Skin Care Preps SODIUM SWEET ALMONDATE 4
05E - Rinses (non-coloring) ANACARDIUM OCCIDENTALE (CASHEW) SEED OIL 1
12C - Face and Neck (exc shave) ANACARDIUM OCCIDENTALE (CASHEW) SEED OIL 3
12D - Body and Hand (exc shave) ANACARDIUM OCCIDENTALE (CASHEW) SEED OIL 4
12F - Moisturizing ANACARDIUM OCCIDENTALE (CASHEW) SEED OIL 2
10E - Other Personal Cleanliness Products CORYLUS AMERICANA (HAZEL) SEED OIL 1
12C - Face and Neck (exc shave) CORYLUS AMERICANA (HAZEL) SEED OIL 4
12D - Body and Hand (exc shave) CORYLUS AMERICANA (HAZEL) SEED OIL 2
12G - Night CORYLUS AMERICANA (HAZEL) SEED OIL 1
12J - Other Skin Care Preps CORYLUS AMERICANA (HAZEL) SEED OIL 1
13C - Other Suntan Preparations CORYLUS AMERICANA (HAZEL) SEED OIL 1
01B - Baby Lotions, Oils, Powders, and Creams CORYLUS AVELLANA (HAZEL) SEED OIL 1
02A - Bath Oils, Tablets, and Salts CORYLUS AVELLANA (HAZEL) SEED OIL 2
03D - Eye Lotion CORYLUS AVELLANA (HAZEL) SEED OIL 1
03G - Other Eye Makeup Preparations CORYLUS AVELLANA (HAZEL) SEED OIL 8
05F - Shampoos (non-coloring) CORYLUS AVELLANA (HAZEL) SEED OIL 1
05I - Other Hair Preparations CORYLUS AVELLANA (HAZEL) SEED OIL 1
07C - Foundations CORYLUS AVELLANA (HAZEL) SEED OIL 1
07E - Lipstick CORYLUS AVELLANA (HAZEL) SEED OIL 2
08G - Other Manicuring Preparations CORYLUS AVELLANA (HAZEL) SEED OIL 1
10E - Other Personal Cleanliness Products CORYLUS AVELLANA (HAZEL) SEED OIL 1
12A - Cleansing CORYLUS AVELLANA (HAZEL) SEED OIL 5
12C - Face and Neck (exc shave) CORYLUS AVELLANA (HAZEL) SEED OIL 41
12D - Body and Hand (exc shave) CORYLUS AVELLANA (HAZEL) SEED OIL 30
12F - Moisturizing CORYLUS AVELLANA (HAZEL) SEED OIL 22
12G - Night CORYLUS AVELLANA (HAZEL) SEED OIL 7
12H - Paste Masks (mud packs) CORYLUS AVELLANA (HAZEL) SEED OIL 10
12J - Other Skin Care Preps CORYLUS AVELLANA (HAZEL) SEED OIL 14
13A - Suntan Gels, Creams, and Liquids CORYLUS AVELLANA (HAZEL) SEED OIL 1
13C - Other Suntan Preparations CORYLUS AVELLANA (HAZEL) SEED OIL 1
02A - Bath Oils, Tablets, and Salts MACADAMIA INTEGRIFOLIA SEED OIL 1
03F - Mascara MACADAMIA INTEGRIFOLIA SEED OIL 3
03G - Other Eye Makeup Preparations MACADAMIA INTEGRIFOLIA SEED OIL 1
05A - Hair Conditioner MACADAMIA INTEGRIFOLIA SEED OIL 1
05G - Tonics, Dressings, and Other Hair Grooming Aids MACADAMIA INTEGRIFOLIA SEED OIL 1
07E - Lipstick MACADAMIA INTEGRIFOLIA SEED OIL 4
10A - Bath Soaps and Detergents MACADAMIA INTEGRIFOLIA SEED OIL 1
10E - Other Personal Cleanliness Products MACADAMIA INTEGRIFOLIA SEED OIL 9
12A - Cleansing MACADAMIA INTEGRIFOLIA SEED OIL 4
12D - Body and Hand (exc shave) MACADAMIA INTEGRIFOLIA SEED OIL 7
12F - Moisturizing MACADAMIA INTEGRIFOLIA SEED OIL 8
13B - Indoor Tanning Preparations MACADAMIA INTEGRIFOLIA SEED OIL 1
02A - Bath Oils, Tablets, and Salts MACADAMIA NUT OIL 1
CIR Panel Book Page 189
2010 FDA Frequency of Use Raw Data
03B - Eyeliner MACADAMIA NUT OIL 8
03C - Eye Shadow MACADAMIA NUT OIL 9
03D - Eye Lotion MACADAMIA NUT OIL 1
03F - Mascara MACADAMIA NUT OIL 1
03G - Other Eye Makeup Preparations MACADAMIA NUT OIL 3
04E - Other Fragrance Preparation MACADAMIA NUT OIL 2
05A - Hair Conditioner MACADAMIA NUT OIL 3
05F - Shampoos (non-coloring) MACADAMIA NUT OIL 4
05G - Tonics, Dressings, and Other Hair Grooming Aids MACADAMIA NUT OIL 1
05I - Other Hair Preparations MACADAMIA NUT OIL 1
07A - Blushers (all types) MACADAMIA NUT OIL 7
07B - Face Powders MACADAMIA NUT OIL 3
07E - Lipstick MACADAMIA NUT OIL 11
07F - Makeup Bases MACADAMIA NUT OIL 11
07G - Rouges MACADAMIA NUT OIL 5
07I - Other Makeup Preparations MACADAMIA NUT OIL 6
08A - Basecoats and Undercoats MACADAMIA NUT OIL 1
08E - Nail Polish and Enamel MACADAMIA NUT OIL 27
12A - Cleansing MACADAMIA NUT OIL 5
12C - Face and Neck (exc shave) MACADAMIA NUT OIL 24
12D - Body and Hand (exc shave) MACADAMIA NUT OIL 18
12F - Moisturizing MACADAMIA NUT OIL 31
12G - Night MACADAMIA NUT OIL 7
12H - Paste Masks (mud packs) MACADAMIA NUT OIL 3
12I - Skin Fresheners MACADAMIA NUT OIL 1
12J - Other Skin Care Preps MACADAMIA NUT OIL 6
13A - Suntan Gels, Creams, and Liquids MACADAMIA NUT OIL 3
13B - Indoor Tanning Preparations MACADAMIA NUT OIL 5
CIR Panel Book Page 190
2010 FDA Frequency of Use Raw Data
01B - Baby Lotions, Oils, Powders, and Creams MACADAMIA TERNIFOLIA SEED OIL 4
02A - Bath Oils, Tablets, and Salts MACADAMIA TERNIFOLIA SEED OIL 2
03B - Eyeliner MACADAMIA TERNIFOLIA SEED OIL 4
03D - Eye Lotion MACADAMIA TERNIFOLIA SEED OIL 8
03F - Mascara MACADAMIA TERNIFOLIA SEED OIL 3
03G - Other Eye Makeup Preparations MACADAMIA TERNIFOLIA SEED OIL 1
04E - Other Fragrance Preparation MACADAMIA TERNIFOLIA SEED OIL 5
05A - Hair Conditioner MACADAMIA TERNIFOLIA SEED OIL 7
05B - Hair Spray (aerosol fixatives) MACADAMIA TERNIFOLIA SEED OIL 5
05F - Shampoos (non-coloring) MACADAMIA TERNIFOLIA SEED OIL 6
05G - Tonics, Dressings, and Other Hair Grooming Aids MACADAMIA TERNIFOLIA SEED OIL 8
05I - Other Hair Preparations MACADAMIA TERNIFOLIA SEED OIL 7
06H - Other Hair Coloring Preparation MACADAMIA TERNIFOLIA SEED OIL 3
07B - Face Powders MACADAMIA TERNIFOLIA SEED OIL 1
07C - Foundations MACADAMIA TERNIFOLIA SEED OIL 3
07D - Leg and Body Paints MACADAMIA TERNIFOLIA SEED OIL 1
07E - Lipstick MACADAMIA TERNIFOLIA SEED OIL 33
07F - Makeup Bases MACADAMIA TERNIFOLIA SEED OIL 1
07G - Rouges MACADAMIA TERNIFOLIA SEED OIL 4
07I - Other Makeup Preparations MACADAMIA TERNIFOLIA SEED OIL 7
08F - Nail Polish and Enamel Removers MACADAMIA TERNIFOLIA SEED OIL 1
10A - Bath Soaps and Detergents MACADAMIA TERNIFOLIA SEED OIL 6
10E - Other Personal Cleanliness Products MACADAMIA TERNIFOLIA SEED OIL 6
11E - Shaving Cream MACADAMIA TERNIFOLIA SEED OIL 1
11G - Other Shaving Preparation Products MACADAMIA TERNIFOLIA SEED OIL 1
12A - Cleansing MACADAMIA TERNIFOLIA SEED OIL 17
12C - Face and Neck (exc shave) MACADAMIA TERNIFOLIA SEED OIL 32
12D - Body and Hand (exc shave) MACADAMIA TERNIFOLIA SEED OIL 90
12E - Foot Powders and Sprays MACADAMIA TERNIFOLIA SEED OIL 2
12F - Moisturizing MACADAMIA TERNIFOLIA SEED OIL 195
12G - Night MACADAMIA TERNIFOLIA SEED OIL 17
12H - Paste Masks (mud packs) MACADAMIA TERNIFOLIA SEED OIL 6
12I - Skin Fresheners MACADAMIA TERNIFOLIA SEED OIL 1
12J - Other Skin Care Preps MACADAMIA TERNIFOLIA SEED OIL 41
13A - Suntan Gels, Creams, and Liquids MACADAMIA TERNIFOLIA SEED OIL 1
13C - Other Suntan Preparations MACADAMIA TERNIFOLIA SEED OIL 3
05A - Hair Conditioner SCHINZIOPHYTON RAUTANENII KERNEL OIL 1
05F - Shampoos (non-coloring) SCHINZIOPHYTON RAUTANENII KERNEL OIL 1
05I - Other Hair Preparations SCHINZIOPHYTON RAUTANENII KERNEL OIL 1
12D - Body and Hand (exc shave) SCHINZIOPHYTON RAUTANENII KERNEL OIL 1
12F - Moisturizing SCHINZIOPHYTON RAUTANENII KERNEL OIL 1
12J - Other Skin Care Preps SCHINZIOPHYTON RAUTANENII KERNEL OIL 1
03G - Other Eye Makeup Preparations CARYA ILLINOENSIS (PECAN) SEED OIL 1
10E - Other Personal Cleanliness Products CARYA ILLINOENSIS (PECAN) SEED OIL 1
12C - Face and Neck (exc shave) CARYA ILLINOENSIS (PECAN) SEED OIL 1
12D - Body and Hand (exc shave) CARYA ILLINOENSIS (PECAN) SEED OIL 2
12F - Moisturizing CARYA ILLINOENSIS (PECAN) SEED OIL 1
12G - Night CARYA ILLINOENSIS (PECAN) SEED OIL 2
01A - Baby Shampoos PISTACIA VERA SEED OIL 2
01C - Other Baby Products PISTACIA VERA SEED OIL 1
02A - Bath Oils, Tablets, and Salts PISTACIA VERA SEED OIL 3
02B - Bubble Baths PISTACIA VERA SEED OIL 4
02D - Other Bath Preparations PISTACIA VERA SEED OIL 1
03B - Eyeliner PISTACIA VERA SEED OIL 2
03C - Eye Shadow PISTACIA VERA SEED OIL 1
03E - Eye Makeup Remover PISTACIA VERA SEED OIL 1
03F - Mascara PISTACIA VERA SEED OIL 1
03G - Other Eye Makeup Preparations PISTACIA VERA SEED OIL 2
05A - Hair Conditioner PISTACIA VERA SEED OIL 3
05F - Shampoos (non-coloring) PISTACIA VERA SEED OIL 7
05G - Tonics, Dressings, and Other Hair Grooming Aids PISTACIA VERA SEED OIL 4
05I - Other Hair Preparations PISTACIA VERA SEED OIL 2
07A - Blushers (all types) PISTACIA VERA SEED OIL 1
07B - Face Powders PISTACIA VERA SEED OIL 1
07E - Lipstick PISTACIA VERA SEED OIL 2
07F - Makeup Bases PISTACIA VERA SEED OIL 1
07I - Other Makeup Preparations PISTACIA VERA SEED OIL 2
08E - Nail Polish and Enamel PISTACIA VERA SEED OIL 1
08G - Other Manicuring Preparations PISTACIA VERA SEED OIL 1
CIR Panel Book Page 191
2010 FDA Frequency of Use Raw Data
09A - Dentifrices PISTACIA VERA SEED OIL 2
09B - Mouthwashes and Breath Fresheners PISTACIA VERA SEED OIL 2
10A - Bath Soaps and Detergents PISTACIA VERA SEED OIL 13
10E - Other Personal Cleanliness Products PISTACIA VERA SEED OIL 2
11A - Aftershave Lotion PISTACIA VERA SEED OIL 1
11F - Shaving Soap PISTACIA VERA SEED OIL 1
12A - Cleansing PISTACIA VERA SEED OIL 5
12C - Face and Neck (exc shave) PISTACIA VERA SEED OIL 28
12D - Body and Hand (exc shave) PISTACIA VERA SEED OIL 14
12F - Moisturizing PISTACIA VERA SEED OIL 28
12G - Night PISTACIA VERA SEED OIL 1
12H - Paste Masks (mud packs) PISTACIA VERA SEED OIL 5
12I - Skin Fresheners PISTACIA VERA SEED OIL 6
12J - Other Skin Care Preps PISTACIA VERA SEED OIL 7
03G - Other Eye Makeup Preparations PLUKENETIA VOLUBILIS SEED OIL 1
07E - Lipstick PLUKENETIA VOLUBILIS SEED OIL 3
12C - Face and Neck (exc shave) PLUKENETIA VOLUBILIS SEED OIL 4
12F - Moisturizing PLUKENETIA VOLUBILIS SEED OIL 2
12G - Night PLUKENETIA VOLUBILIS SEED OIL 2
12H - Paste Masks (mud packs) PLUKENETIA VOLUBILIS SEED OIL 1
02D - Other Bath Preparations JUGLANS REGIA (WALNUT) SEED OIL 2
03D - Eye Lotion JUGLANS REGIA (WALNUT) SEED OIL 1
05A - Hair Conditioner JUGLANS REGIA (WALNUT) SEED OIL 1
12C - Face and Neck (exc shave) JUGLANS REGIA (WALNUT) SEED OIL 2
12D - Body and Hand (exc shave) JUGLANS REGIA (WALNUT) SEED OIL 7
12F - Moisturizing JUGLANS REGIA (WALNUT) SEED OIL 1
12J - Other Skin Care Preps JUGLANS REGIA (WALNUT) SEED OIL 1
CIR Panel Book Page 192
2010 FDA Frequency of Use Raw Data
01C - Other Baby Products COCONUT ACID 1
03B - Eyeliner COCONUT ACID 1
05F - Shampoos (non-coloring) COCONUT ACID 1
07B - Face Powders COCONUT ACID 2
07C - Foundations COCONUT ACID 8
10A - Bath Soaps and Detergents COCONUT ACID 99
10E - Other Personal Cleanliness Products COCONUT ACID 2
11A - Aftershave Lotion COCONUT ACID 1
11E - Shaving Cream COCONUT ACID 15
11F - Shaving Soap COCONUT ACID 1
12A - Cleansing COCONUT ACID 5
12C - Face and Neck (exc shave) COCONUT ACID 1
12D - Body and Hand (exc shave) COCONUT ACID 1
12F - Moisturizing COCONUT ACID 1
12H - Paste Masks (mud packs) COCONUT ACID 1
12J - Other Skin Care Preps COCONUT ACID 1
01B - Baby Lotions, Oils, Powders, and Creams COCOS NUCIFERA (COCONUT) OIL 8
01C - Other Baby Products COCOS NUCIFERA (COCONUT) OIL 7
02A - Bath Oils, Tablets, and Salts COCOS NUCIFERA (COCONUT) OIL 3
02B - Bubble Baths COCOS NUCIFERA (COCONUT) OIL 1
02D - Other Bath Preparations COCOS NUCIFERA (COCONUT) OIL 11
03B - Eyeliner COCOS NUCIFERA (COCONUT) OIL 7
03C - Eye Shadow COCOS NUCIFERA (COCONUT) OIL 3
03D - Eye Lotion COCOS NUCIFERA (COCONUT) OIL 4
03E - Eye Makeup Remover COCOS NUCIFERA (COCONUT) OIL 3
03G - Other Eye Makeup Preparations COCOS NUCIFERA (COCONUT) OIL 8
04A - Cologne and Toilet waters COCOS NUCIFERA (COCONUT) OIL 3
04C - Powders (dusting and talcum, excluding aftershave talc) COCOS NUCIFERA (COCONUT) OIL 1
04E - Other Fragrance Preparation COCOS NUCIFERA (COCONUT) OIL 5
05A - Hair Conditioner COCOS NUCIFERA (COCONUT) OIL 50
05C - Hair Straighteners COCOS NUCIFERA (COCONUT) OIL 21
05F - Shampoos (non-coloring) COCOS NUCIFERA (COCONUT) OIL 28
05G - Tonics, Dressings, and Other Hair Grooming Aids COCOS NUCIFERA (COCONUT) OIL 40
05I - Other Hair Preparations COCOS NUCIFERA (COCONUT) OIL 37
06A - Hair Dyes and Colors (all types requiring caution statements and patch tests)COCOS NUCIFERA (COCONUT) OIL 65
06B - Hair Tints COCOS NUCIFERA (COCONUT) OIL 1
06G - Hair Bleaches COCOS NUCIFERA (COCONUT) OIL 3
07A - Blushers (all types) COCOS NUCIFERA (COCONUT) OIL 3
07B - Face Powders COCOS NUCIFERA (COCONUT) OIL 3
07C - Foundations COCOS NUCIFERA (COCONUT) OIL 4
07D - Leg and Body Paints COCOS NUCIFERA (COCONUT) OIL 1
07E - Lipstick COCOS NUCIFERA (COCONUT) OIL 44
07I - Other Makeup Preparations COCOS NUCIFERA (COCONUT) OIL 12
08B - Cuticle Softeners COCOS NUCIFERA (COCONUT) OIL 2
08G - Other Manicuring Preparations COCOS NUCIFERA (COCONUT) OIL 3
10A - Bath Soaps and Detergents COCOS NUCIFERA (COCONUT) OIL 147
10E - Other Personal Cleanliness Products COCOS NUCIFERA (COCONUT) OIL 14
11E - Shaving Cream COCOS NUCIFERA (COCONUT) OIL 6
11G - Other Shaving Preparation Products COCOS NUCIFERA (COCONUT) OIL 9
12A - Cleansing COCOS NUCIFERA (COCONUT) OIL 20
12B - Depilatories COCOS NUCIFERA (COCONUT) OIL 4
12C - Face and Neck (exc shave) COCOS NUCIFERA (COCONUT) OIL 13
12D - Body and Hand (exc shave) COCOS NUCIFERA (COCONUT) OIL 65
12E - Foot Powders and Sprays COCOS NUCIFERA (COCONUT) OIL 1
12F - Moisturizing COCOS NUCIFERA (COCONUT) OIL 82
12G - Night COCOS NUCIFERA (COCONUT) OIL 3
12H - Paste Masks (mud packs) COCOS NUCIFERA (COCONUT) OIL 3
12I - Skin Fresheners COCOS NUCIFERA (COCONUT) OIL 3
12J - Other Skin Care Preps COCOS NUCIFERA (COCONUT) OIL 24
13A - Suntan Gels, Creams, and Liquids COCOS NUCIFERA (COCONUT) OIL 13
13B - Indoor Tanning Preparations COCOS NUCIFERA (COCONUT) OIL 8
13C - Other Suntan Preparations COCOS NUCIFERA (COCONUT) OIL 2
01C - Other Baby Products HYDROGENATED COCONUT OIL 1
03A - Eyebrow Pencil HYDROGENATED COCONUT OIL 2
03B - Eyeliner HYDROGENATED COCONUT OIL 3
03C - Eye Shadow HYDROGENATED COCONUT OIL 1
03G - Other Eye Makeup Preparations HYDROGENATED COCONUT OIL 1
05A - Hair Conditioner HYDROGENATED COCONUT OIL 2
05G - Tonics, Dressings, and Other Hair Grooming Aids HYDROGENATED COCONUT OIL 1
07B - Face Powders HYDROGENATED COCONUT OIL 3
07C - Foundations HYDROGENATED COCONUT OIL 4
CIR Panel Book Page 193
2010 FDA Frequency of Use Raw Data
07E - Lipstick HYDROGENATED COCONUT OIL 10
07I - Other Makeup Preparations HYDROGENATED COCONUT OIL 4
10A - Bath Soaps and Detergents HYDROGENATED COCONUT OIL 16
10E - Other Personal Cleanliness Products HYDROGENATED COCONUT OIL 2
11E - Shaving Cream HYDROGENATED COCONUT OIL 1
11F - Shaving Soap HYDROGENATED COCONUT OIL 1
12A - Cleansing HYDROGENATED COCONUT OIL 3
12C - Face and Neck (exc shave) HYDROGENATED COCONUT OIL 10
12D - Body and Hand (exc shave) HYDROGENATED COCONUT OIL 7
12F - Moisturizing HYDROGENATED COCONUT OIL 21
12H - Paste Masks (mud packs) HYDROGENATED COCONUT OIL 1
12J - Other Skin Care Preps HYDROGENATED COCONUT OIL 9
13B - Indoor Tanning Preparations HYDROGENATED COCONUT OIL 2
10A - Bath Soaps and Detergents MAGNESIUM COCOATE 9
05F - Shampoos (non-coloring) POTASSIUM COCOATE 2
10A - Bath Soaps and Detergents POTASSIUM COCOATE 18
10E - Other Personal Cleanliness Products POTASSIUM COCOATE 8
11E - Shaving Cream POTASSIUM COCOATE 3
11F - Shaving Soap POTASSIUM COCOATE 1
12A - Cleansing POTASSIUM COCOATE 8
01C - Other Baby Products SODIUM COCOATE 5
02B - Bubble Baths SODIUM COCOATE 3
05A - Hair Conditioner SODIUM COCOATE 1
05F - Shampoos (non-coloring) SODIUM COCOATE 65
05G - Tonics, Dressings, and Other Hair Grooming Aids SODIUM COCOATE 1
05I - Other Hair Preparations SODIUM COCOATE 4
10A - Bath Soaps and Detergents SODIUM COCOATE 226
10E - Other Personal Cleanliness Products SODIUM COCOATE 12
11A - Aftershave Lotion SODIUM COCOATE 1
11E - Shaving Cream SODIUM COCOATE 2
11F - Shaving Soap SODIUM COCOATE 2
12A - Cleansing SODIUM COCOATE 12
12H - Paste Masks (mud packs) SODIUM COCOATE 1
12J - Other Skin Care Preps SODIUM COCOATE 5
03D - Eye Lotion ARACHIS HYPOGAEA (PEANUT) OIL 1
03G - Other Eye Makeup Preparations ARACHIS HYPOGAEA (PEANUT) OIL 3
05A - Hair Conditioner ARACHIS HYPOGAEA (PEANUT) OIL 8
05G - Tonics, Dressings, and Other Hair Grooming Aids ARACHIS HYPOGAEA (PEANUT) OIL 7
05I - Other Hair Preparations ARACHIS HYPOGAEA (PEANUT) OIL 6
07I - Other Makeup Preparations ARACHIS HYPOGAEA (PEANUT) OIL 1
10A - Bath Soaps and Detergents ARACHIS HYPOGAEA (PEANUT) OIL 2
12A - Cleansing ARACHIS HYPOGAEA (PEANUT) OIL 5
12C - Face and Neck (exc shave) ARACHIS HYPOGAEA (PEANUT) OIL 16
12D - Body and Hand (exc shave) ARACHIS HYPOGAEA (PEANUT) OIL 6
12E - Foot Powders and Sprays ARACHIS HYPOGAEA (PEANUT) OIL 2
12F - Moisturizing ARACHIS HYPOGAEA (PEANUT) OIL 7
12G - Night ARACHIS HYPOGAEA (PEANUT) OIL 3
12J - Other Skin Care Preps ARACHIS HYPOGAEA (PEANUT) OIL 5
13A - Suntan Gels, Creams, and Liquids ARACHIS HYPOGAEA (PEANUT) OIL 1
13B - Indoor Tanning Preparations ARACHIS HYPOGAEA (PEANUT) OIL 1
12C - Face and Neck (exc shave) HYDROGENATED PEANUT OIL 3
12D - Body and Hand (exc shave) HYDROGENATED PEANUT OIL 5
12G - Night HYDROGENATED PEANUT OIL 3
12J - Other Skin Care Preps HYDROGENATED PEANUT OIL 1
01B - Baby Lotions, Oils, Powders, and Creams BUTYROSPERMUM PARKII (SHEA BUTTER) 19
01C - Other Baby Products BUTYROSPERMUM PARKII (SHEA BUTTER) 5
02A - Bath Oils, Tablets, and Salts BUTYROSPERMUM PARKII (SHEA BUTTER) 9
02B - Bubble Baths BUTYROSPERMUM PARKII (SHEA BUTTER) 1
02D - Other Bath Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 3
03A - Eyebrow Pencil BUTYROSPERMUM PARKII (SHEA BUTTER) 3
03B - Eyeliner BUTYROSPERMUM PARKII (SHEA BUTTER) 9
03C - Eye Shadow BUTYROSPERMUM PARKII (SHEA BUTTER) 10
03D - Eye Lotion BUTYROSPERMUM PARKII (SHEA BUTTER) 52
03E - Eye Makeup Remover BUTYROSPERMUM PARKII (SHEA BUTTER) 1
03F - Mascara BUTYROSPERMUM PARKII (SHEA BUTTER) 5
03G - Other Eye Makeup Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 28
04E - Other Fragrance Preparation BUTYROSPERMUM PARKII (SHEA BUTTER) 7
CIR Panel Book Page 194
2010 FDA Frequency of Use Raw Data
05A - Hair Conditioner BUTYROSPERMUM PARKII (SHEA BUTTER) 64
05B - Hair Spray (aerosol fixatives) BUTYROSPERMUM PARKII (SHEA BUTTER) 2
05C - Hair Straighteners BUTYROSPERMUM PARKII (SHEA BUTTER) 23
05E - Rinses (non-coloring) BUTYROSPERMUM PARKII (SHEA BUTTER) 2
05F - Shampoos (non-coloring) BUTYROSPERMUM PARKII (SHEA BUTTER) 32
05G - Tonics, Dressings, and Other Hair Grooming Aids BUTYROSPERMUM PARKII (SHEA BUTTER) 50
05I - Other Hair Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 37
06D - Hair Shampoos (coloring) BUTYROSPERMUM PARKII (SHEA BUTTER) 1
06H - Other Hair Coloring Preparation BUTYROSPERMUM PARKII (SHEA BUTTER) 3
07A - Blushers (all types) BUTYROSPERMUM PARKII (SHEA BUTTER) 9
07B - Face Powders BUTYROSPERMUM PARKII (SHEA BUTTER) 1
07C - Foundations BUTYROSPERMUM PARKII (SHEA BUTTER) 15
07E - Lipstick BUTYROSPERMUM PARKII (SHEA BUTTER) 128
07F - Makeup Bases BUTYROSPERMUM PARKII (SHEA BUTTER) 4
07G - Rouges BUTYROSPERMUM PARKII (SHEA BUTTER) 1
07I - Other Makeup Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 41
08B - Cuticle Softeners BUTYROSPERMUM PARKII (SHEA BUTTER) 4
08C - Nail Creams and Lotions BUTYROSPERMUM PARKII (SHEA BUTTER) 2
08G - Other Manicuring Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 1
10A - Bath Soaps and Detergents BUTYROSPERMUM PARKII (SHEA BUTTER) 59
10B - Deodorants (underarm) BUTYROSPERMUM PARKII (SHEA BUTTER) 2
10E - Other Personal Cleanliness Products BUTYROSPERMUM PARKII (SHEA BUTTER) 42
11A - Aftershave Lotion BUTYROSPERMUM PARKII (SHEA BUTTER) 17
11B - Beard Softeners BUTYROSPERMUM PARKII (SHEA BUTTER) 1
11E - Shaving Cream BUTYROSPERMUM PARKII (SHEA BUTTER) 7
11G - Other Shaving Preparation Products BUTYROSPERMUM PARKII (SHEA BUTTER) 2
12A - Cleansing BUTYROSPERMUM PARKII (SHEA BUTTER) 45
12B - Depilatories BUTYROSPERMUM PARKII (SHEA BUTTER) 2
12C - Face and Neck (exc shave) BUTYROSPERMUM PARKII (SHEA BUTTER) 153
12D - Body and Hand (exc shave) BUTYROSPERMUM PARKII (SHEA BUTTER) 269
12E - Foot Powders and Sprays BUTYROSPERMUM PARKII (SHEA BUTTER) 8
12F - Moisturizing BUTYROSPERMUM PARKII (SHEA BUTTER) 516
12G - Night BUTYROSPERMUM PARKII (SHEA BUTTER) 84
12H - Paste Masks (mud packs) BUTYROSPERMUM PARKII (SHEA BUTTER) 21
12I - Skin Fresheners BUTYROSPERMUM PARKII (SHEA BUTTER) 4
12J - Other Skin Care Preps BUTYROSPERMUM PARKII (SHEA BUTTER) 107
13A - Suntan Gels, Creams, and Liquids BUTYROSPERMUM PARKII (SHEA BUTTER) 11
13B - Indoor Tanning Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 21
13C - Other Suntan Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 7
02A - Bath Oils, Tablets, and Salts BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 1
02B - Bubble Baths BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 2
03D - Eye Lotion BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 1
10A - Bath Soaps and Detergents BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 3
12F - Moisturizing BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 12
12G - Night BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 2
12J - Other Skin Care Preps BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 1
01B - Baby Lotions, Oils, Powders, and Creams BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1
03B - Eyeliner BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 3
03C - Eye Shadow BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 4
05A - Hair Conditioner BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1
05F - Shampoos (non-coloring) BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 2
05I - Other Hair Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 2
07A - Blushers (all types) BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 3
07B - Face Powders BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 4
07C - Foundations BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1
07E - Lipstick BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 2
12C - Face and Neck (exc shave) BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 5
12D - Body and Hand (exc shave) BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1
12F - Moisturizing BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 8
12J - Other Skin Care Preps BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1
CIR Panel Book Page 195
2010 FDA Frequency of Use Raw Data
10A - Bath Soaps and Detergents HYDROGENATED SHEA BUTTER 2
12F - Moisturizing HYDROGENATED SHEA BUTTER 2
02A - Bath Oils, Tablets, and Salts ALEURITES MOLUCCANA SEED OIL 5
02B - Bubble Baths ALEURITES MOLUCCANA SEED OIL 1
03D - Eye Lotion ALEURITES MOLUCCANA SEED OIL 2
03F - Mascara ALEURITES MOLUCCANA SEED OIL 3
03G - Other Eye Makeup Preparations ALEURITES MOLUCCANA SEED OIL 1
04E - Other Fragrance Preparation ALEURITES MOLUCCANA SEED OIL 8
05A - Hair Conditioner ALEURITES MOLUCCANA SEED OIL 15
05B - Hair Spray (aerosol fixatives) ALEURITES MOLUCCANA SEED OIL 7
05E - Rinses (non-coloring) ALEURITES MOLUCCANA SEED OIL 1
05F - Shampoos (non-coloring) ALEURITES MOLUCCANA SEED OIL 15
05G - Tonics, Dressings, and Other Hair Grooming Aids ALEURITES MOLUCCANA SEED OIL 12
05H - Wave Sets ALEURITES MOLUCCANA SEED OIL 1
05I - Other Hair Preparations ALEURITES MOLUCCANA SEED OIL 7
07E - Lipstick ALEURITES MOLUCCANA SEED OIL 1
08B - Cuticle Softeners ALEURITES MOLUCCANA SEED OIL 1
08C - Nail Creams and Lotions ALEURITES MOLUCCANA SEED OIL 2
08G - Other Manicuring Preparations ALEURITES MOLUCCANA SEED OIL 1
10A - Bath Soaps and Detergents ALEURITES MOLUCCANA SEED OIL 2
10E - Other Personal Cleanliness Products ALEURITES MOLUCCANA SEED OIL 3
11E - Shaving Cream ALEURITES MOLUCCANA SEED OIL 1
12A - Cleansing ALEURITES MOLUCCANA SEED OIL 3
12C - Face and Neck (exc shave) ALEURITES MOLUCCANA SEED OIL 2
12D - Body and Hand (exc shave) ALEURITES MOLUCCANA SEED OIL 14
12F - Moisturizing ALEURITES MOLUCCANA SEED OIL 23
12G - Night ALEURITES MOLUCCANA SEED OIL 1
12J - Other Skin Care Preps ALEURITES MOLUCCANA SEED OIL 5
13A - Suntan Gels, Creams, and Liquids ALEURITES MOLUCCANA SEED OIL 1
13B - Indoor Tanning Preparations ALEURITES MOLUCCANA SEED OIL 1
13C - Other Suntan Preparations ALEURITES MOLUCCANA SEED OIL 2
02B - Bubble Baths BERTHOLLETIA EXCELSA SEED OIL 3
03D - Eye Lotion BERTHOLLETIA EXCELSA SEED OIL 1
05A - Hair Conditioner BERTHOLLETIA EXCELSA SEED OIL 5
05F - Shampoos (non-coloring) BERTHOLLETIA EXCELSA SEED OIL 5
05I - Other Hair Preparations BERTHOLLETIA EXCELSA SEED OIL 2
06A - Hair Dyes and Colors (all types requiring caution statements and patch tests)BERTHOLLETIA EXCELSA SEED OIL 14
07C - Foundations BERTHOLLETIA EXCELSA SEED OIL 1
10A - Bath Soaps and Detergents BERTHOLLETIA EXCELSA SEED OIL 3
10E - Other Personal Cleanliness Products BERTHOLLETIA EXCELSA SEED OIL 4
12C - Face and Neck (exc shave) BERTHOLLETIA EXCELSA SEED OIL 2
12D - Body and Hand (exc shave) BERTHOLLETIA EXCELSA SEED OIL 1
12E - Foot Powders and Sprays BERTHOLLETIA EXCELSA SEED OIL 1
12F - Moisturizing BERTHOLLETIA EXCELSA SEED OIL 11
12H - Paste Masks (mud packs) BERTHOLLETIA EXCELSA SEED OIL 1
12J - Other Skin Care Preps BERTHOLLETIA EXCELSA SEED OIL 1
12C - Face and Neck (exc shave) GEVUINA AVELLANA OIL 2
12D - Body and Hand (exc shave) GEVUINA AVELLANA OIL 2
12F - Moisturizing GEVUINA AVELLANA OIL 1
CIR Panel Book Page 196
DATE:
Products CouncilCommitted to Safety,Quality & Innovation
John Bailey, Ph.15EZ\3_i_.._O___.. £[i toIndustry Liaison to the CIR Expert Panel
June 29, 2010
SUBJECT: HRIPT of a Lipstick Containing Plukenetia Volubilis Seed Oil
Consumer Product Testing Co. 2008. Repeated insult patch test of a lipstick containing 0.509847%Plukenetia Volubilis Seed Oil. Experiment Reference Number C08-5394.06.
1101 17th Street, N.W., Suite 30O Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org
Personal Carei
Memorandum
TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (Cifi)
FROM:
CIR Panel Book Page 197
CIR Panel Book Page 198
CIR Panel Book Page 199
CIR Panel Book Page 200
CIR Panel Book Page 201
CIR Panel Book Page 202
CIR Panel Book Page 203
CIR Panel Book Page 204
CIR Panel Book Page 205
CIR Panel Book Page 206
CIR Panel Book Page 207
CIR Panel Book Page 208
CIR Panel Book Page 209
CIR Panel Book Page 210
Personal Care Products CounciCommitted to Safety,Quality & Innovation
Memorandum
TO:
FROM:
DATE:
SUBJECT:
F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (CW)
John Bailey,Industry Liaison to the CIR Expert Panel
July 19, 2010
Composition and specifications of 6 nut oils
John L Seaton & Co Ltd. 2005. Seatons Arachis Oil Data sheet.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
John L Seaton & Co Ltd.
2010.
2005.
2009.
2005.
2010.
2005.
2010.
2006.
2006.
2005.
2009.
1101 17th Street, N.W., Suite 300 Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org
Arachis Oil BP/EP Specification.
Seatons Shea Nut Butter Data sheet.
Seatons Refined Shea Nut Butter Specification.
Seatons Hazelnut Oil Data sheet.
Seatons Refined Hazelnut Oil Specification.
Seatons Macadamia Oil Data sheet.
Seatons Refined Macadamia Oil Specification.
Seatons Kukui Nut Oil Data sheet.
Seatons Refined Kukui Nut Oil Specification.
Seatons Sweet Almond Oil Data sheet.
Seatons Refined Sweet Almond Oil Cosmetic Blend Specification.
CIR Panel Book Page 211
OriginAlso know as peanut oil and groundnut oil, arachis oil is obtained from the seed kernels ofArachis hypogaea (L) which is grown in some parts of Europe, Africa, India and China. Itis refined to give pale yellow oil with a slight odour and mild taste.
Characteristics and applicationsArachis oil has traditionally been used in sunscreens and after sun formulations. It canalso be used in products to treat dry skin conditions.
• R & D arachis oil to meet BP, EP and USP specs• Organic arachis oil
Typical propertiesFree fatty acidsIodine valueSaponification valueRelative density @ 20°CRefractive index @ 40°CColour, Lovibond 5.25” cellRequired HLB value
0.5 max80- 106185 - 1950.9 12 - 0.9201.462 - 1.46420 yellow, 2.5 red max6
Typical fatty acid profilePalmitic C16Stearic C18Oleic C18:1Linoleic C18:2Linolenic C18:3
7- 16%1 - 6%35 - 72%13 - 43%0.6% max
Registration informationINCI nameCAS numberEINECS number
Arachis Hypogaea Oil8002-03-7232-296-4
Specifications, starting formulations and MSDS are available on request.
Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (April 2005).
John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44 (0)1482 579700 Fax + 44 (0)1482 647313Website www.croda.com/seatonsEmail cosmetic@seatons-uk.co.uk
Seatons Arachis Oil
Range available
CIR Panel Book Page 212
Specification
Acid value - 0.5
Peroxide value - 5.0
Unsaponifiable matter - 1.0% w/w
Alkaline impurities Complies with the test for alkalineimpurities in fatty oils
Moisture content (if intended for the - 0.3%use in parenteral forms)
Fatty acid composition Mm Max
Saturated fatty acids of - 0.4%
chain length less than C16
C16:0 Palmitic acid 7.0% 16.0%
C18:0 Stearic acid 1.3% 6.5%
C18:1 Oleic acid 35.0% 72.0%
C18:2 Linoleic acid 13.0% 43.0%
C18:3 Linolenic acid - 0.6%
C20:0 Arachidic acid 0.5% 3.0%
C20:1 Eicosenoic acid 0.5% 2.1%
C22:0 Behenic acid 1.0% 5.0%
C22:1 Erucic acid - 0.5%
C24:0 Lignoceric acid 0.5% 3.0%
Supplied under a quality management system registered to ISO 9001
Non-warrantyThe information in this publication is believed to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is made.Suggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representation or warranty, express or implied, is made with respect to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or non-infnngement of any third party patent or other intellectual property rights induding without limit copyright, trademark and designs.Any trademarks identified herein are trademarks 0f the Croda group of companies.
John L Seaton & Co LimitedFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44(0)1482 647313Website www.seatons-uk.co.ukEmail enquirieaaeatons-uk.co.uk
Product Arachis Oil BP/EP
Definition Arachis oil is the fixed oil obtained from the shelled seeds of Arachis hypogaea(L) and further refined. It conforms to the monograph contained in the BritishPharmacopoeia 2010 and European Pharmacopoeia 6.0.
Characteristics
JLS specification number
Test
A clear, yellowish, viscous oil.Very slightly soluble in alcohol, miscible with light petroleumRelative density about 0.915. It solidifes at about 2°C.
P9046
Range MethodMm Max
Methods as described in the
British Pharmacopoeia
Date of issueConfirmed
Storage conditions Arachis oil should be kept in a well filled, well closed container and protectedfrom light.
Issued by PA Bentley
August2009January 2010
CIR Panel Book Page 213
Seatons Shea Nut Butter
OriginShea nut butter is a rich buttery oil produced by cold pressing the fruits of the shea tree(Butyrospermum parkii), which is grown in central Africa. Shea trees are hard todomesticate and only start bearing fruit after 15/20 years. Each tree bears on average 15-20 kg of fruit which yield just 1 .5kg of butter. Shea nut buffer is also known as Karite butterand is a creamy white/off white solid at room temperature.
Characteristics and applicationsShea nut butter has skin soothing and replenishing properties so is mainly used inproducts for the protection of dry and cracked skin. It can also be used in soaps as it hasa relatively high melting point.
Range available
• Refined shea nut buffer• Organic shea nut buffer
Typical propertiesAcid value 1.5 maxIodine value 45-73Saponification value 165-190Colour, Lovibond 5.25” cell 20 yellow, 3 red maxSlip melting point 28 - 42CCRequired HLB value 8
Typical fatty acid profilePalmitic C16 3-9%Stearic C18 34-48%Oleic C18:1 38-50%Linoleic C18:2 3-8%Linolenic C18:3 0.5% max
Monounsaturated fatty acids 45%Saturated fatty acids 47%Polyunsaturated fatty acids 6%Trans fatty acids 0
Registration informationINCI name Butyrospermum Parkii ButterCAS number 68956-68-3EINECS number 273-313-5
Specification and MSDS available on request.
Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (April 2005),
John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44 (0)1482 579700 Fax + 44(0)1482647313Website www.croda.com/seatonsEmail cosmetics@seatons-uk.co.uk
CIR Panel Book Page 214
Specification
Product Seatons Refined Shea Nut Butter
Description Speciality vegetable oil obtained from the kernels of the Shea tree(Butyrospermum parkii)
JLS specification number P9010
Test Range Method
Mm Max
Physical Properties
Appearance Off white / yellow solid Visual
Chemical Properties
Free fatty Acid content (% as oleic) - 1.0 BS 684: Section 2.10
Iodine Value (gI2JlOOg oil) 45 73 BS 684: Section 2.13
Peroxide value (meqO2lkg) - 5.0 BS 684: Section 2.14
Fatty Acid Profile (main acids) GLC
C16:0 Palmitic acid 2.0 8.0%
Cl 8:0 Stearic acid 36.0 50.0%
C18:1 Oleic acid 40.0 50.0%
C18:2 Linoleic acid 4.0 8.0%
C20:0 Arachidic acid - 3.0%
Issued by: P.A.Bentley
Date of issue: December 2009
Supplied under a quality management system registered to Iso 9001
Non-warrantyThe information in this publication is believed to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is made.Suggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representahon or warranty. eopress or implied, is made with rasped to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or non-infringement of any third party patentor other intellectual property rights including without limit copyright, trademark and designs.My trademarks identified herein are trademarks of the Croda group of companies.
John L Seaton & Co limitedFirst Floor 7 Waterside Susiness Park Livingstone Road
Hessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44 (0)1482 647313Website www.seatons-uk.co.ukEmail enquiries@seatons-uk.co.uk
CIR Panel Book Page 215
Seatons Hazelnut Oil
OriginHazelnut oil is produced from the nut kernels of the hazelnut shrub, grown in West Africa.The oil is extracted by mechanical pressing followed by filtration and the oil can be furtherrefined.
Characteristics and applicationsHazelnut is rich in vitamins and is easily absorbed into skin where it nourishes andrevitalises all skin types. Hazelnut oil is said to tone and tighten the skin and helpsmaintain firmness and elasticity. It spreads onto skin easily, is lubricating, and therefore isa very good base oil for massage. It also makes a good bath oil.
Range available
• Cold pressed hazelnut oil• Refined hazelnut oil• Organic hazelnut oil
Typical propertiesAcid value 0.6 max (refined)Iodine value 85 - 97Saponification value 188 - 195Relative density @ 15.5°C 0.912 - 0.917Refractive index @ 20°C 1.467 - 1.474
Typical fatty acid profilePalmitic C16 5 - 9%Palmitoleic C16:1 0.5% maxStearic C18 1 -4%Oleic C18:1 66 - 83%Linoleic C18:2 8 - 25%Linolenic C18:3 0.6% max
Registration informationINCI name Corylus Avellana (Hazel) Seed OilCAS number 68956-68-3EINECS number 273-313-5
Specifications, starting formulations and MSDS are available on request.
Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (April 2005).
John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44(0)1482579700 Fax + 44(0)1482647313Website www.croda.com/seatonsEmail cosmetics@seatons-uk.co.uk
CIR Panel Book Page 216
Specification
Product Seatons Refined Hazlenut Oil
Description Speciality vegetable oil
JLS specification number P9062
Test Range MethodMm Max
Colour - 25 Yellow 2.5 Red Lovibond 5.25” cell
Saponification value (mgKOH/g) 187 197 BS 684 : Section 2.6
Peroxide (meqO2lkg) - 10.0 BS 684: Section 2.14
Free fatty acid content (% as oleic) - 0.2 BS 684 : Section 2.10
Iodine value (g12/1 COg) 83 90 BS 684: Section 2.13
Fatty acid profile GLC
C16:0 Palmitic acid 5.0 9.0%
C16:1 Palmitoleic acid - 1.0%
018:0 Stearic acid 2.0 6.0%
018:1 Oleic acid 68 85%
C18:2 Linoleic acid 7.0 15.0%
018:3 Linolenic acid - 0.5%
Issued by: P.A.Bentley
Date of issue: May 2010
Supplied under a quality management system registered to ISO 9001
Non-warrantyThe information in this publication in belieued to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is made.Suggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representation or warranty, eupress or implied, is made with respect to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or non-infringement of any third party patent or other intellectual property rights including without limit copyright, trademark and designs.Any trademarks identified herein are trademarks of the Croda group of companies.
John L Seaton & Co UmitedFirst Floor 7 Waterside Business Park Livingutone RoadHessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44 (0)1482 6473 13Website www.seatons-uk.co.ukEmail enquiries@seatons_uk.co.uk
CIR Panel Book Page 217
Seatons Macadamia Oil
OriginMacadamia oil is the oil extracted from the nuts of the macadamia tree (Macadamiaternifolia). The oil is a golden yellow colour, which after refining becomes pale yellow.
Characteristics and applicationsMacadamia oil is unique in that it contains a high percentage of palmitoleic acid. It is ahighly emollient oil with anti-ageing properties and is a good conditioning agent for dry andmature skin. It is easily absorbed into the skin and promotes skin suppleness. The oil canbe used in a wide range of skin preparations and sun care products.
Range available
• Cold pressed macadamia oil• Refined macadamia oil• Organic macadamia oil
Typical propertiesFree fatty acids 0.5 MaxIodine value 70 - 80Saponification value 190 -200Relative density20°C 0.911 -0.918
Refractive index @ 20°C 1.466 - 1.470Required HLB value 7
Typical fatty acid profilePalmitic C16 7.5 - 10%Palmitoleic C16:1 16—24%Stearic C18 2-4%Oleic C18:1 53-67%Linoleic C18:2 1.5-4%Linolenic C18:3 0.5% maxArachic C20 1.5 — 3%Gadoleic C20:1 1.5 — 3%Others 7% max
Monounsaturated fatty acids 82%Saturated fatty acids 14%Polyunsaturated fatty acids 4%Trans fatty acids 0
Registration informationINCI name Macadamia Ternifolia Seed OilCAS number 128497-20-1 and 129811-19-4EINECS number 273-313-5
Specifications, starting formulations and MSDS are available on request.
Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (April 2005).
John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44(0)1482 579700 Fax + 44(0)1482647313Website www.croda.com/seatonsEmail cosmetics@seatons-uk.co.uk
CIR Panel Book Page 218
Product
Description
Issued by: P.A.Bentley
Seatons Refined Macadamia Oil
Speciality vegetable oil
P9014
RangeMm Max
Clear light yellow oil
10.0
Date of issue: January 2010
Non-warrantyThe informahon in this publication is believed to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is made.Suggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representation or warranty, eopress or implied, is made with respect to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or noninfringenient of any third party patent or other intellectual property rights including without limit copyright, trademark and designs.Any trademarks identified herein are trademarks of the Crude group of companies,
John L Seaton & Co UmitedFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44 (0)1482 647313Website www.seatons-uk.co.ukEmail enquiries@seatons_uk.co.uk
Specification
JLS specification number
Test Method
Appearance Visual
Peroxide (meqO2lkg) BS 684 : Section 2.14
Free fatty acid content (% as oleic) 1.0 BS 684: Section 2.10
Iodine value (g12/lOOg) 62 82 BS 684: Section 2.13
Fatty acid profile GLC
C16:0 Palmitic acid 6.0 12.0%
C16:1 Palmitoleic acid 12.0 25.0%
C18:0 Stearicacid 0.5 8.0%
C18:1 Oleic acid 50.0 67.0%
C18:2 Linoleic acid - 5.0%
C20:0 Arachidic acid - 5.0%
Supplied under a quality management system registered to ISO 9001
CIR Panel Book Page 219
Seatons Kukul Nut Oil
OriginKukui nut oil is pressed from the nuts of the tropical kukul nut tree (Aleurites molucana).These tree grow mainly in Hawaii, Indonesia and Malaysia and are also known ascandle/candleberry, kemiri nut, lumbang and varnish trees.
Characteristics and applicationsThe Hawaiians have used kukui nut oil for centuries to protect and heal skin that isexposed to the sun, wind and salt water. The oil is high in essential fatty acids and iseasily absorbed by the skin where it softens, moisturises and helps soothe and renew dry,mature, sunburnt, sensitive and problem skin. Kukui nut oil is especially useful in facialskin care products as it is light, non greasy and is said to be able to penetrate the stratumcorneum leaving a semi permeable barrier containing both saturated and unsaturated fattyacids. It is also a good choice of oil for bar soaps, bath gels, massage and baby careproducts.
• Pressed kukui nut oil• Refined kukui nut oil
Typical propertiesAppearanceFree fatty acidsIodine valueSaponification valueRelative density @ 15.5°CRefractive index @ 20°C
Clear yellow liquid2% max (refined grade)130 - 175185-2100.920 - 0.9401.470-1.480
Typical fatty acid profilePalmitic C16Stearic C18Oleic C18:1Linoleic C18:2Alpha LinoIenicCl8:3
5-8%2 - 5%15- 30%35 - 45%24 - 34%
Registration informationINCI nameCAS numberEINECS number
Aleurites Moluccana Seed Oil8015-80-3 & 68956-68-3273-313-5
Specification and MSDS are available on request.
Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (June 2006).
John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44(0)1482 579700 Fax + 44 (0)1 482 647313Website www.croda.com/seatonsEmail cosmetic@seatons-uk.co.uk
Range available
CIR Panel Book Page 220
Specification
Product
Description
JLS specification number J9073-00
Test
Physical status @ 25°C
Colour
Peroxide value meqO2lkg
Acid value
Unsaponifiable matter
Density @ 20°C
Refractive Index
Iodine value g12/100g
Saponification value mgKOH/g
Typical fatty acid profile
C16:0 Palmitic
C16:1 Palmitoleic
C18:0 Stearic
C18:1 Oleic
C18:2 Linoleic
C18:3 x-Linolenic
C20:0 Arachidic
C20:1 Eicosenoic
Max
Liquid
Light yellow
5.0
1.0
1.0%
0.930
1.480
175
210
7.0%
0.5%
0.1%
35.0%
50%
40.0%
1.5%
1.0%
Method
Visual
Visual
AOCS Cd3a-63
ASTM D1298-85
ASTM D1248-92
AOCS Tg2a-64
ISO 3657-1 988
Issued byAuthorised by
S M PritchardP A Bentley
Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assume anyliability expressed or implied in the presentation of this data, nor should information contained herein be construed asgranting licence to practise any methods or compositions of matter covered by British or other patents. Specificationdetails are correct at the date of issue.
Updated April 2006
John L Seaton & Co limitedFirst Floor, 7 Waterside Business Park. Livingstone RoadHessle, East Yorkshire, HU 13 OEG, United KingdomTel + 44(0)1482579700 Fax + 44(0)1482647313Website: www.croda.com/seatonsEmail: cosmetics@seatons-uk.co.uk
I
Seatons Refined Kukui Nut Oil
Speciality vegetable oil
RangeMm
0.920
1.470
130
185
6.0%
10.0%
35%
25.0%
Supplied under a quality systemregistered to ISO 9001 :2000
CIR Panel Book Page 213
Seatons Sweet Almond OilOriginSweet almond oil is the fixed oil extracted from the kernels of almonds (Prunus amygdalusdulcis), which are commonly grown in Mediterranean countries and the west coast ofAmerica. It is also known as almond oil. The kernels are mechanically pressed and thekernels yield 40-50% oil. This oil can then be refined to give a pale yellow, viscous oil witha characteristic mild odour and taste.
Characteristics and applicationsSweet almond oil is rich in oleic and linoleic fatty acids and also contains vitamins A, Bi,B2 and B6 as well as a small amount of vitamin E. It is widely used in cosmeticformulations as a skin conditioning agent due to its penetrating, smoothing, softening andmoisturising properties. As it can protect and nourish a wide range of skin types and cancalm irritations caused by eczema it is an excellent choice of ingredient for moisturisingpreparations. The oil is also reported to be particularly good at treating dry, brittle nails.As sweet almond oil blends well with many other oils and is a good general lubricating oilit is ideal for use as a massage oil and a carrier oil for aromatherapy.
Range available
• Refined almond oil cosmetics blend• Refined almond oil which conforms to BP and EP specifications• Organic almond oil
Typical propertiesFree fatty acids 1% maxIodine value 93-105Saponification value 185-195Relative density @ 20°C 0.911-0.920Refractive index @ 20°C 1.467-1.473Colour, Lovibond 5.25” cell 3.5R maxRequired HLB value 7
Typical fatty acid profilePalmitic C16 6%Stearic C18 3%Oleic C18:1 69%Linoleic C18:2 17%Linolenic C18:3 0.4%
Registration informationINCI name Prunus Amygdalus Dulcis OilCAS number 8007-69-0EINECS number 273-313-5
Specifications, MSDS and starting formulations are available on request.
Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (April 2005).
John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44 (0)1 482 579700 Fax + 44 (0)1 482 647313Website www.croda.com/seatonsEmail cosmetics@seatons-uk.co.uk
CIR Panel Book Page 214
Specification
Product Seatons Refined Sweet Almond Oil Cosmetic Blend
Appearance
Specific gravity @ 20°C
Refractive Index @ 20°C
Saponification value (mgKOH/g)
Peroxide (meqO2lkg)
Acid value (mgKOH/g)
Iodine value gl2/lOOg
Fatty acid profile (main acids)
C16:0 Palmitic acid
C16:1 Palmitoleic acid
C18:0 Stearic acid
C18:1 Oleic acid
C18:2 Linoleic acid
C18:3 Linolenic acid
C20:0 Arachidic acid
C20:1 Gadoleic acid
C22:0 Behenic acid
C24:0 Lignoceric acid
Mm Max
Clear, light yellow liquid
0.910 0.930
1.465 1.475
185 200
10.0
0.5
95 109
9.0%
2.0%
3.0%
75.0%
30.0%
0.5%
0.3%
0.3%
0.8%
0.5%
Method
Visual
BS 718
BS 684: Section 1.2
BS 684: Section 2.6
BS 684: Section 2.14
BS 684: Section 2.10
BS 684: Section 2.13
GLC
Issued by: P.A.Bentley
Date of issue: October 2009
Non-warrantyThe information In this publication is believed to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is macfeSuggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representation or warranty, express or implied, is made with respect to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or non-infringement of any third party patent or other intellectual property rights induding without limit copyright, trademark and designs.My trademarks identified herein are trademarks of the Croda group of companies.
John L Seaton & Co UmitedFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44 (0)1482 647313Website www.seatons-uk.co.ukEmail etnquiries©seatons-uk.co.uk
Description
Test
JLS specification number P9053
A blend of refined sweet almond oil and other refined vegetable oils
Range
3.0
1.0
60.0
20.0
Supplied Under a quality management system registered to ISO 9001
CIR Panel Book Page 215
Personal Care Products CouncilCommitted to Safety,Quality & Innovation
Memorandum
TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (CIR)
FROM: John Bailey, Ph.D.Industry Liaison to the Cifi Expert Panel
DATE: July 26, 2010
SUBJECT: Updated Concentration of Use Butyrospermum Parkii (Shea) Butter
The 80% face product in the original table is actually a mask that is diluted to 30% ButyrospermumParkii (Shea) Butter before use. The attached updated table reflects this change.
1101 17th Street, N.W., Suite 30O Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org CIR Panel Book Page 216
Concentration of Use - Butyrospermum Parkii (Shea) Butter, Butyrospermum Parkii (Shea)Butter Extract, Butyrospermum Parkii (Shea) Butter Unsaponifiables, Butyrospermum Parkii(Shea) Nut Extract, Butyrospermum Parkii (Shea) Nut Shell Powder, Butyrospermum Parkii
(Shea) Oil, Butyrospermum Parkii (Shea) Seedcake Extract, Coco/Shea Butter Glycerides,Hydrogenated Shea Butter, Hydrolyzed Shea Seedcake Extract, PEG-50 Shea Butter, PEG-60 Shea
Butter Glycerides, PEG-75 Shea Butter Glycerides, Polyglyceryl-4 Almondate/Shea Butterate,Polyglyceryl-3 Soyate/Shea Butterate, Shea Butteramide/Castoramide DEA, Shea Butter CetylEsters, Shea Butter Decyl Esters, Shea Butter Glycereth-8 Esters, Shea Butter Glyceride, Shea
Butter Glycerides, Shea Butter Oleyl Esters, Shea Butter PEG-12 Dimethicone Esters, Shea ButterPEG-8 Esters and Shea Butter Polyglyceryl-6 Esters*
Ingredient Product Category Concentrationof Use
Butyrospermum Parkii (Shea) Butter Baby lotions, oils powders and 0.1-5%creams
Butyrospermum Parkii (Shea) Butter Other baby products 0.0 1-0.3%
Butyrospermum Parkii (Shea) Butter Bath oils, tablets and salts 1%
Butyrospermum Parkii (Shea) Butter Eyebrow pencil 0.1-6%
Butyrospermum Parkii (Shea) Butter Eyeliner 0.1-8%
Butyrospermum Parkii (Shea) Butter Eye shadow 0.5-6%
Butyrospermum Parkii (Shea) Butter Eye lotion 0.5-7%
Butyrospermum Parkii (Shea) Butter Mascara 0.5%
Butyrospermum Parkii (Shea) Butter Perfumes 0.2-0.8%
Butyrospermum Parkii (Shea) Butter Other fragrance preparations 0.00 1-1%
Butyrospermum Parkii (Shea) Butter Hair conditioners 0.0005-1%
Butyrospermum Parkii (Shea) Butter Hair straighteners 0.1-1%
Butyrospermum Parkii (Shea) Butter Shampoos (noncoloring) 0.001-1%
Butyrospermum Parkii (Shea) Butter Tonics, dressings and other hair 0.1-2%grooming aids
Butyrospermum Parkii (Shea) Butter Other hair preparations 0.5-3%(noncoloring)
Butyrospermum Parkii (Shea) Butter Blushers (all types) 0.1-1%
Butyrospermum Parkii (Shea) Butter Face powders 0.2-2%
Butyrospermum Parkii (Shea) Butter Foundations 0.4-20%
Page 1 of 6
CIR Panel Book Page 217
Butyrospermum Parkii (Shea) Butter Leg and body paints 6%
Butyrospermum Parkii (Shea) Butter Lipstick 0.5-26%
Butyrospermum Parkii (Shea) Butter Other makeup preparations1 1-6%
Butyrospermum Parkii (Shea) Butter Cuticle softener 18-60%
Butyrospermum Parkii (Shea) Butter Nail creams and lotions 2-25%
Butyrospermum Parkii (Shea) Butter Nail polish and enamel 0.05%
Butyrospermum Parkii (Shea) Butter Nail polish and enamel removers 3%
Butyrospermum Parkii (Shea) Butter Other manicuring preparations 0.01%
Butyrospermum Parkii (Shea) Butter Bath soaps and detergents 0.003-3%
Butyrospermum Parkii (Shea) Butter Deodorants (underarm) 1%
Butyrospermum Parkii (Shea) Butter Other personal cleanliness products2 0.1-5%
Butyrospermum Paridi (Shea) Butter Aftershave lotions 0.2-4%
Butyrospermum Parkii (Shea) Butter Shaving cream (aerosol, brushless 0.0 1-2%and lather)
Butyrospermum Parkii (Shea) Butter Skin cleansing (cold creams, 0.03-10%cleansing lotions, liquids and pads)
Butyrospermum Parkii (Shea) Butter Depilatories 0.3%
Butyrospermum Parkii (Shea) Butter Face and neck creams, lotions and 0.04-19%powders
Butyrospermum Parkii (Shea) Butter Body and hand creams, lotions and 0.4-45%powders
Butyrospermum Parkii (Shea) Butter Body and hand sprays 1%
Butyrospermum Parkii (Shea) Butter Foot powders and sprays 1-3%
Butyrospermum Parkii (Shea) Butter Moisturizing creams, lotions and 0.003-11%powders
Butyrospermum Parkii (Shea) Butter Night creams, lotions and powders 0.03-6%
Butyrospermum Parkii (Shea) Butter Paste masks (mud packs) 0.1-30%
Butyrospermum Parkii (Shea) Butter Other skin care preparations 0.01-16%
Butyrospermum Parkii (Shea) Butter Suntan gels, creams, and liquids 0.5-8%
Butyrospermum Parkii (Shea) Butter Indoor tanning preparations 2%
Page 2 of 6
CIR Panel Book Page 218
Butyrospemum Paridi (Shea) Butter Other suntan preparations ]_1%
Butyrospermum Parkii (Shea) Butter Extract Bath oils, tablets and salts 0.03%
Butyrospermum Parkii (Shea) Butter Extract Bubble baths 1%
Butyrospermum Parkii (Shea) Butter Extract Other bath preparations 0.03-1%
Butyrospermum Parkii (Shea) Butter Extract Eyebrow pencil 0.2%
Butyrospermum Parkii (Shea) Butter Extract Eye lotion 0.5-2%
Butyrospermum Parkii (Shea) Butter Extract Hair conditioners 0.0 1%
Butyrospermum Parkii (Shea) Butter Extract Tonics, dressings and other hair 1%grooming aids
Butyrospermum Parkii (Shea) Butter Extract Other hair preparations 1%(noncoloring)
Butyrospermum Parkii (Shea) Butter Extract Foundations 0.009%
Butyrospermum Parkii (Shea) Butter Extract Lipstick 0.1-6%
Butyrospermum Parkii (Shea) Butter Extract Nail creams and lotions 0.0 1%
Butyrospermum Parkii (Shea) Butter Extract Bath soaps and detergents 0.03-1%
Butyrospermum Parkii (Shea) Butter Extract Deodorants (underarm) 0.03%
Butyrospermum Parkii (Shea) Butter Extract Preshave lotions (all types) 0.03%
Butyrospermum Parkii (Shea) Butter Extract Skin cleansing (cold creams, 0.006-1%cleansing lotions, liquids and pads)
Butyrospermum Parkii (Shea) Butter Extract Depilatories 0.0 1-0.3%
Butyrospermum Parkii (Shea) Butter Extract Face and neck creams, lotions and 2%powders
Butyrospermum Parkii (Shea) Butter Extract Body and hand creams lotions and 0.02-5%powders
Butyrospermum Parkii (Shea) Butter Extract Body and hand sprays 0.5-1%
Butyrospermum Parkii (Shea) Butter Extract Other skin care preparations 0.3%
Butyrospermum Parkii (Shea) Butter Extract Suntan gels, creams and liquids 0.1%
Butyrospermum Parkii (Shea) Butter Extract Other suntan preparations 0.5%
Butyrospermum Parkii (Shea) Butter Eyebrow pencil 0.2%Unsaponifiables
Butyrospermum Parkii (Shea) Butter Eyeliner 0.7%
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CIR Panel Book Page 219
Unsaponifiables
Butyrospermum Parkii (Shea) Butter Eye shadow 0.4%Unsaponifiables
Butyrospermum Parkii (Shea) Butter Other hair preparations 2%Unsaponifiables (noncoloring)
Butyrospermum Parkii (Shea) Butter Blushers (all types) 0.06%Unsaponifiables
Butyrospermum Parkii (Shea) Butter Face powders 0.2-1%Unsaponifiables
Butyrospermum Parkii (Shea) Butter Lipstick 1-3%Unsaponifiables
Butyrospermum Parkii (Shea) Butter Rouges 0.06%Unsaponifiables
Butyrospermum Parkii (Shea) Butter Face and neck creams, lotions and 3%Unsaponifiables powders
Butyrospermum Parkii (Shea) Butter Body and hand creams, lotions and 1%Unsaponifiables powders
Butyrospermum Parkii (Shea) Butter Night creams, lotions and powders 2%Unsaponifiables
Butyrospermum Parkii (Shea) Butter Other skin care preparations 2%Unsaponifiables
Butyrospermum Parkii (Shea) Oil Bath oils, tablets and salts 1%
Butyrospermum Parkii (Shea) Oil Bubble baths 1%
Butyrospermum Parkii (Shea) Oil Lipstick 15%
Butyrospermum Parkii (Shea) Oil Other manicuring preparations 0.01-1%
Butyrospermum Parkii (Shea) Oil Bath soaps and detergents 0.6%
Butyrospermum Parkii (Shea) Oil Aftershave lotions 1%
Butyrospermum Parkii (Shea) Oil Skin cleansing (cold creams, 1%cleansing lotions, liquids and pads)
Hydrogenated Shea Butter Other personal cleanliness products 1%
Hydrogenated Shea Butter Skin cleansing (cold creams, 1%cleansing lotions, liquids and pads)
Hydrogenated Shea Butter Body and hand creams, lotions and 1%
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CIR Panel Book Page 220
powders
Hydrogenated Shea Butter Other skin care preparations 1%
PEG-50 Shea Butter Other baby products3 0.1%
PEG-50 Shea Butter Bath oils, tablets and salts 2%
PEG-50 Shea Butter Hair conditioners 0.00 1%
PEG-50 Shea Butter Shampoos (noncoloring) 0.001%
PEG-50 Shea Butter Other hair preparations 0.001%(noncoloring)
PEG-50 Shea Butter Other personal cleanliness products4 3%
PEG-50 Shea Butter Skin cleansing (cold creams, 3%cleansing lotions, liquids and pads)
PEG-50 Shea Butter Face and neck creams, lotions and 0.1%powders
PEG-50 Shea Butter Body and hand creams, lotions and 0.1-1%powders
PEG-50 Shea Butter Paste masks (mud packs) 0.1 %
PEG-50 Shea Butter Skin fresheners 2%
PEG-75 Shea Butter Glycerides Bubble baths 1%
PEG-75 Shea Butter Glycerides Other fragrance preparations 0.5%
PEG-75 Shea Butter Glycerides Hair conditioners 0.1%
PEG-75 Shea Butter Glycerides Shampoos (noncoloring) 0.3%
PEG-75 Shea Butter Glycerides Tonics, dressings and other hair 0.02%grooming aids
PEG-75 Shea Butter Glycerides Bath soaps and detergents 0.1-3%
PEG-75 Shea Butter Glycerides Douches 0.1%
PEG-75 Shea Butter Glycerides Skin cleansing (cold creams, 1%cleansing lotions, liquids and pads)
PEG-75 Shea Butter Glycerides Face and neck creams, lotions and 0.1%powders
PEG-75 Shea Butter Glycerides Body and hand creams, lotions and 0.002-1%powders
Page 5 of 6
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Shea Butter Glycerides Lipstick
Shea Butter Glycerides Skin cleansing (cold creams,cleansing lotions, liquids and pads)
*Ingredients included in the title of the table, but not found in the table were included in the survey, butno uses were reported.11% in a face highlighter21% in a shower gelO. 1% in a rinse-off product43% in a hand scrub
Information collected in 2009Table prepared September 17, 2009
Updated July 26, 2010
Page 6 of 6
CIR Panel Book Page 218
Personal Care Products CouncilCommitted to Safety,Quality & Innovation
Memorandum
TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (CIR)
FROM: John Bailey, Ph.D 3-(ri Ii’Industry Liaison to the CIR Expert Panel
DATE: July 19, 2010
SUBJECT: Comments on the Scientific Literature Review of Nut Oils
pA - In the Introduction, please change “as they are used in cosmetic ingredients.” to “as they are usedin cosmetic products.”
p.4 - In the Introduction, please change “triglycerides composed of mixtures of fatty acids” to“triglycerides containing various fatty acids”.
p.4- - At the start of the Chemistry section, please clarify what is meant by “The group”. Fats and oilsare not just derived from plants as this paragraph seems to imply.
p.8 - Is it correct to call all the oils in this report “edible”?p.8 - Unless there was evidence of dermal absorption of Prunus Amygdalus Dulcis (Sweet Almond)
Oil, please change “percutaneous absorption” to “percutaneous exposure”.p.10 - Please indicate the number guinea pigs and types of assays, e.g., maximization, in which the
sensitization potential of Cocos Nucifera (Coconut) Oil and Hydrogenated Coconut Oil wasstudied. If studies were done on both substances, both substances should be in the subsectionheading.
p.10 - Please provide the type of in vitro studies that were used to study the potential ocular effects ofAleurites Moluccana Seed Oil. What species was used in the in vivo study?
p.12 - As Singh et al. (2004) (reference 41) completed a tumor promotion study, did they include aconclusion regarding the tumor promoting potential of Anacardium Ocidentale (Cashew) SeedOil?
p.14- - The following is not a complete sentence. “A bar soap contining 13% coconut oil evaluated forskin irritation using standard Draize procedures.”
p.15 - It would be helpful to indicate the number of subjects treated with cosmetic formulationscontaining 25% Prunus Amygdalus Dulcis (Sweet Almond) Oil.
p.17, Item 5 - As the oils are triglycerides not mixtures of fatty acids, having irritation and sensitizationtesting of individual fatty acids is not necessary. If irritation and sensitization data on the fattyacids is needed, CIR staff should look for published information. Searching PubMed forLinolenic Acid and sensitization the following was the first reference identified.
Kreilling R, Hollnagal HM, Hareng L, et al. 2008. Comparison of the skin sensitizationpotential of unsaturated compounds as assessed by the murine local lymph node
1101 17th Street, N.W., Suite 300 Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org CIR Panel Book Page 219
assay (LLNA) and the guinea pig maximization test (GPMT). Food ChemicalToxicology 46(6): 1896-1904.
p.17 - Request 6 is not clear. If this review is focused only on the composition of the ingredients andthe dermal effects of the ingredients, why is “any other information that pertains to the safety ofuse in cosmetics” necessary? Requests to industry should reflect the same criteria CIR staffused for identifying information in the published literature. If all types of safety information areneeded from industry, CIR staff need to go back and identify all the relevant published safetyinformation on these oils.
2
CIR Panel Book Page 220
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