Building the Virtual Physiological Human - CellML · liver (i.e. in the space of Disse)’; Thank...

Building the Virtual Physiological Human

Bernard de Bonobdb@ebi.ac.uk

a. rate of urinary urea excretionb. rate of O2 delivery to muscle tissuesc. rate of change of plasma proteind. left atrial ANP secretione. total ADH secretionf. afferent arteriolar resistanceg. vascular resistance through muscle tissuesh. alveolar ventilationi. diuretic effect on tubular reabsorptionj. arterial O2 content

a. rate of urinary urea excretionb. rate of O2 delivery to muscle tissuesc. rate of change of plasma proteind. left atrial ANP secretione. total ADH secretionf. afferent arteriolar resistanceg. vascular resistance through muscle tissuesh. alveolar ventilationi. diuretic effect on tubular reabsorptionj. arterial O2 content

a. rate of urinary urea excretionb. rate of O2 delivery to muscle tissuesc. rate of change of plasma proteind. left atrial ANP secretione. total ADH secretionf. afferent arteriolar resistanceg. vascular resistance through muscle tissuesh. alveolar ventilationi. diuretic effect on tubular reabsorptionj. arterial O2 content

COMPLEX

MOLECULE

DBID:#3

DBID:#5

Two scenarios:

(i) the ‘level of oxygen in erythrocytes in the coronary blood’;

(ii) ‘the basement extracellular matrix that links sinusoidal endothelium with hepatocytes in the liver (i.e. in the space of Disse)’;

Thank You

Bernard de Bonobdb@ebi.ac.uk