Bioinformatics for Vet. Part XVIII

Bioinformatics for Vet. Part XVIIIBioinformatics for Vet. Part XVIII

Sung Youn Lee, PhD. StudentSung Youn Lee, PhD. StudentVeterinary collage, Room 320Veterinary collage, Room 32002 450 3719, 016 293 605902 450 3719, 016 293 6059

leevet@paran.comleevet@paran.com

Digestion in the Duodenum

• The partially digested proteins coming from the stomach will have their fragments further digested by: – Trypsin which cleaves peptides on the carboxyl side of the ba

sic amino acids Lys and Arg. – Chymotrypsin which cleaves on the carboxyl side of the arom

atic amino acids Phe, Tyr and Trp. • A zinc requiring enzyme.

– Carboxypeptidase which cleaves all amino acids on the remaining fragments one amino acid at a time from the carboxyl side. (This would be cutting the N-side of the C-terminal amino acid.)

Digesting a protein in a Digesting a protein in a computercomputer

• http://www.expasy.org/

Thank you for your attention ~Thank you for your attention ~