Automated Immunoassays Multi-test immunoassays are the most widely used rapid test format –...

Automated Immunoassays

• Multi-test immunoassays are the most widely used rapid test format – worldwide– ELISA / EIA (Assurance EIA, TECRA)– ELFA (Vidas)

• Benefits– Low cost/test– Low labor cost with automation– Capable of high throughput– Validated, proven technology

Full automation of EIA procedure

Sample dispensing

Reagent delivery

Washing

Incubation

Photometric reading

Results interpretation

BioControl EIA AutomationBioControl EIA Automation

Continuous Loading

Bi-directional LIMS Compatibility

High Throughput Up to 186 samples and controls per run Continuous loading

Highly adaptable open platform• Pre-programmed for TRANSIA® PLATE• Pre-programmed for Assurance EIA®

• Compatible with all EIA assays

BioControl EIA Automation BioControl EIA Automation OptionsOptions

• BioControl EIA’s

Final Enrichment

Transfer 1 mL to Cluster tubes

Inactivationheating block

Load tubes and ReagentOn Gemini

• Vidas

Final Enrichment

Transfer 0.5 mL toVidas Test Strip

InactivationHeating Block

Load Test Strips andSPRs on Vidas

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Comparison of Through-put

Throughput of 1 Gemini = 3 Vidas Systems

  Gemini Vidas

8 h 480 samples 168 - 280 samples

24 h 1600 samples 560 - 896 samples

Gemini vs VidasCapability Gemini Vidas Winner

Max Capacity 288 samples / controls

30 samples / controls

Gemini

Continuous Loading Yes No Gemini

Multiple Assays per Run Yes Yes – limited by capacity

Gemini

Hands-on Time Minimized by high sample

capacity

Increased by low sample

capacity

Gemini

Individual Run Time Approx 2 hr Approx 1 hr Vidas

Overall Run Time Minimized by high sample

capacity

Increased by low sample

capacity

Gemini

Calibration 1 / year 28 / year Gemini

Barcode Reader Yes Yes Equivalent

LIMS Capability Yes Yes Equivalent

• Automates each and every step

WASH

Washer • 8 channels • Aspirate / dispense needles• 3 wash buffers • Customized wash patterns

PIPET

Pipettor • Disposable tips• Capacitive liquid level detection• Pipetting pressure monitoring• 300 µL tips (10-300 µL) – Samples• 1100 µL tips (301-1000 µL) - Reagents

• Automates each and every step

INCUBATE

2 incubator chambers • Independently controlled• Shaking capacity• Temperatures up to 45°C

3 ambient temperature positions

Unique modular design •Easy service & Maintenance•Minimizes down time•Reduces repair costs

READ

Absorbance reader • 400-700 nm wavelength• Single or dual wavelength• Range 0.0 – 3.0 OD

• On-board Computer

Computer Ports • 3 USB ports for external peripheral

keyboard, mouse, printer, etc…• VGA monitor port • LAN cable connection• PS2 port

Touch-Screen Interface• Full function user interface

• Automates each and every step and MORE!

Multiple Assays• Same plate –common protocol• Different plates – common protocol or

different protocols

Continuous loading of resources• Plates and tips• Samples, and reagents• Instrument will show when Plate 3 can be loaded

Continuous operation• Initiate new assays during run

• Flexible to meet your high throughput needs

Accepts individual sample tubes or cluster tubes

12 loading bay lanes• Accepts both sample and reagent racks

Accepts reagent bottles directly from kit

• No reagent transfer

Automated resource tracking• Reagent volume tracking• Disposable tip tracking

Resource verification• Are reagents present • Sufficient reagent volume• Sufficient tips

Automatic schedule optimization• Multiple plates / assays• Addition of new samples/ assays

Assurance EIA Pathogen TestsAssurance EIA Pathogen Tests

• TRANSIA® PLATE Salmonella Gold

• TRANSIA® PLATE Listeria

• TRANSIA® PLATEListeria

monocytogenes• TRANSIA® PLATE

Staphylococcal Enterotoxins

TRANSIA PLATE EIA Pathogen TRANSIA PLATE EIA Pathogen TestsTests

*TRANSIA® is also available for Allergen and Chemical Residue detection