1 Abiogenesis Part 1 Proteins and Evolution Nils Confer, PhD MBA 10/11/2012

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Abiogenesis Part 1Abiogenesis Part 1

Proteins and EvolutionProteins and Evolution

Nils Confer, PhD MBANils Confer, PhD MBA

10/11/201210/11/2012

22

Evenings OutlineEvenings Outline

• Two camps, two choices, two sides of Two camps, two choices, two sides of coin?coin?

• Cells - a brief introductionCells - a brief introduction

• Ribosomes - protein synthesisRibosomes - protein synthesis

• Protein folding, folds, and “evolution”Protein folding, folds, and “evolution”

• Other examples of protein complexes Other examples of protein complexes and a discussion of “irreducible and a discussion of “irreducible complexity”complexity”

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Evenings OutlineEvenings Outline

• Two camps, two choices, two sides of Two camps, two choices, two sides of coin?coin?

• Cells - a brief introductionCells - a brief introduction

• Ribosomes - protein synthesisRibosomes - protein synthesis

• Protein folding, folds, and “evolution”Protein folding, folds, and “evolution”

• Other examples of protein complexes Other examples of protein complexes and a discussion of “irreducible and a discussion of “irreducible complexity”complexity”

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Creation or “Evolution”? Creation or “Evolution”? ChooseChoose!!

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““Naturalism” Owns Naturalism” Owns Science…?Science…?

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A Belief Based in Ignorance?A Belief Based in Ignorance?

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Two Sides of the Same Two Sides of the Same Coin?Coin?

Evolutionist View of Abiogenesis

Inorganic Materials

Building Blocks

Polymers

Polymers with Advantages

Hypercycle

Protobiont

Bacteria

Multicellular Organisms

Complex and Diverse Life

Creationist View of Abiogenesis

Inorganic Materials

Complex and Diverse Life

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Two Sides of the Same Two Sides of the Same Coin?Coin?

Evolutionist View of Abiogenesis

Inorganic Materials

Building Blocks

Polymers

Polymers with Advantages

Hypercycle

Protobiont

Bacteria

Multicellular Organisms

Complex and Diverse Life

Creationist View of Abiogenesis

Inorganic Materials

Complex and Diverse Life

99

Evenings OutlineEvenings Outline

• Two camps, two choices, two sides of Two camps, two choices, two sides of coin?coin?

• Cells - a brief introductionCells - a brief introduction

• Ribosomes - protein synthesisRibosomes - protein synthesis

• Protein folding, folds, and “evolution”Protein folding, folds, and “evolution”

• Other examples of protein complexes Other examples of protein complexes and a discussion of “irreducible and a discussion of “irreducible complexity”complexity”

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Cells are Extremely Cells are Extremely Complex!Complex!

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Cells – Irreducible Cells – Irreducible Complexity?Complexity?

• Minimal Genome ProjectMinimal Genome Project

• Smallest natural cellsSmallest natural cells

• LUCALUCA

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The Language of Life – The Language of Life – Communication out of Chaos?Communication out of Chaos?

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Evenings OutlineEvenings Outline

• Two camps, two choices, two sides of Two camps, two choices, two sides of coin?coin?

• Cells - a brief introductionCells - a brief introduction

• Ribosomes - protein synthesisRibosomes - protein synthesis

• Protein folding, folds, and “evolution”Protein folding, folds, and “evolution”

• Other examples of protein complexes Other examples of protein complexes and a discussion of “irreducible and a discussion of “irreducible complexity”complexity”

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Ribosomes – Protein Ribosomes – Protein FactoriesFactories

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Ribosomes – Genetic Code to Ribosomes – Genetic Code to Flesh and BloodFlesh and Blood

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Evenings OutlineEvenings Outline

• Two camps, two choices, two sides of Two camps, two choices, two sides of coin?coin?

• Cells - a brief introductionCells - a brief introduction

• Ribosomes - protein synthesisRibosomes - protein synthesis

• Protein folding, folds, and “evolution”Protein folding, folds, and “evolution”

• Other examples of protein complexes Other examples of protein complexes and a discussion of “irreducible and a discussion of “irreducible complexity”complexity”

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NucleosomesNucleosomes

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Amino Acid Sequence Amino Acid Sequence ConservationConservation

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Evenings OutlineEvenings Outline

• Two camps, two choices, two sides of Two camps, two choices, two sides of coin?coin?

• Cells - a brief introductionCells - a brief introduction

• Ribosomes - protein synthesisRibosomes - protein synthesis

• Protein folding, folds, and “evolution”Protein folding, folds, and “evolution”

• Other examples of protein complexes Other examples of protein complexes and a discussion of “irreducible and a discussion of “irreducible complexity”complexity”

2020

Protein ComplexesProtein Complexes

• RibosomesRibosomes

• NucleosomesNucleosomes

• FlagellumFlagellum

• DNA replicationDNA replication

• DNA transcriptionDNA transcription

• DNA repairDNA repair

• Nuclear poreNuclear pore

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Flagellated MotorsFlagellated Motors

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Nuclear Pore ComplexNuclear Pore Complex

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Science Does Not Advance If Science Does Not Advance If We Do Not QuestionWe Do Not Question

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Abiogenesis Part 2Abiogenesis Part 2

From Inorganic MaterialsFrom Inorganic Materials

to LUCAto LUCA

Nils Confer, PhD MBANils Confer, PhD MBA

10/18/201210/18/2012