Don Duval: Driving Innovation and Commercialization in Life Sciences

Building Canada’s next generation of growth companies

Driving Commercial Outcomes from Innovation and Technology - The MaRS Discovery District Case Study November 29th 2011

There are three objectives that I hope to achieve in today’s presentation:

1.  Provide an overview of MaRS, our mandate, and the programs and services we offer

2.  Discuss the MaRS Life Sciences and Healthcare Practice, MaRS Innovation, and the MaRS EXCITE program

3.  Provide an opportunity to address any questions you may have

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MaRS is a non-profit innovation centre connecting science, technology and social entrepreneurs with business skills, networks and capital

MaRS helps to create successful global businesses from Canada’s science and technology

Mission

Who we Serve

Early stage science and technology ventures and innovative social purpose businesses

Measure of Success Job and wealth creation for the economy

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5

Discovery Details in Notes Part of Slide

pg  8  

Phase I"Phase II"

Discovery District Financial District Creative & Arts District

Gardiner Museum of Ceramic Art Royal Ontario Museum

Women’s College

The MaRS Centre UHN Toronto General Hospital for Sick children

Entertainment District

Four Seasons Centre

University of Toronto

UHN Princess Margaret Mount Sinai

Art Gallery of Ontario

Royal Conservatory of Music

TIFF & OCAD

Financial District

Toronto Rehab Ryerson University

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pg  11  

Building Next Generation Startups

Improving Commercialization

Output from Academe

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MaRS Innovation

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¨ A professionally managed, business accelerator platform as a single point of entry for industry partners and investors

¨ Funding of MaRS Innovation and distribution of revenues are

based upon an agreed upon formula amongst all member institutions

¨ Currently trending with approximately 300 disclosures per year, approximately 70% of which are life sciences, medical device, or healthcare IT sectors

¨ Cash contributions from member institutions are based pro-rata on the annual research budget for each institution

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Educationand Insight"

Entrepreneurship Education

Market Research"Thought Leadership"

Access

to Capital""

Angels"Venture Capital"

Corporations"Government Programs"

Foundations""

Business Advice and Mentorship"

"Advisors"

Volunteers""

Networks, Talent, Customers and Partners"

Programs for High Growth Ventures, Policy Initiatives, and Special Projects "

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ICE Cleantech Life Sciences

and Healthcare

| |

Due Diligence Financing

Human Resources and Talent Management

Intellectual Property

Market/Competitive Intelligence

Marketing & Sales

Corporate Governance

Financial Management, Accounting, Tax

Legal Product Development and Marketing

Operations and Process Customer Relationship Management

Strategic Partnerships

Strategy and Business Planning

Partners Volunteers MaRS Advisors

| Social

| |

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Pg 17

¨ Approximately 125 active ventures in the MaRS portfolio, working with an array of mentors and advisors

¨ Provision of market intelligence, educational resources, and continuing to build strong connections to capital and market opportunities

¨ Highly integrated and supportive of MaRS Innovation clients; pipeline of high quality deal flow

Logoʼs from ArcticDX, Profound Medical, "

Single Commercialization Storefront for Toronto’s Academic Institutions

Business Accelerator for Ontario’s Emerging

Companies

Entrepreneurs from across Ontario and

the country"St

art-u

ps"

Member Institutions"

Lice

nsin

g &

Indu

stry

C

o-de

velo

pmen

t "

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Memory at Work

NEW TECHNOLOGIES"

END USERS"

Currently there is limited crosstalk during the development process can mean greatly protracted timelines before new technologies are adopted or even a reluctance to adopt new technologies

Pg 19 19

Unrealized improvements

Demand "

disconnect""

A novel approach that matches health technology innovation with patient needs and health system priorities"

"

NOW"

New Canadian "

Medical Technologies"

New Canadian and International"

Medical Technologies"

Pre-market feedback loop"

More relevant technologies"""

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Memory at Work

Current Evaluation Process"

Technology Development"

Market Approval"

Sub-optimal Adoption by Health Systems"

Pre-Market"Evaluation"

(Risk-Based)"

Post-Market"Evaluation"

(Evidence-Based)"

Incorporates technology improvements"

Reflects health care priorities"

"

EXCITE Pre-Market Evaluation Process"

Technology Development with Evaluation Improvements"

Market Approval"

Optimal Adoption by Health Systems"

Pre-Market"Evaluation"

(Evidence-Based)"

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Impact"

Business Services"

Ecosystem Development"

IP Development |"

MaRS Advisory |"

Market Intelligence |"

Entrepreneurship Education"

Capital & Investment"

Strategic Partnerships | Stakeholder Support"

Community Programs |" Awards & Recognition"

Talent & Knowledge Management "

Real Estate Services "

MaRS Centre Development "

IT/AV Services"

Office & Laboratory Facilities | MaRS Incubator "

MaRS Collaboration Centre l "

Public Policy "

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Don Duval"Email: dduval@marsdd.com"Twitter: don_duval"Speakerfile: don.duval"