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  • PERANGSANG S.S.PANALEPTIKOBAT

    2 (DUA) MEKANISME :Menghambat Sistem PenghambatanMerangsang Sinaps

  • XANTINKAFEINTEOFILINTEOBROMINFARMAKODINAMISXANTIN Merangsang SSP Diuresis Relaksasi Otot Polos (Bronkus) Merangsang Otot Jantung

  • S.S.P Kafein & Teofilin >> Teobromin

  • JANTUNG Kafein & Teofilin Takikardi & AritmiaPEMBULUH DARAH :Vs Dilatasi(Sebentar)

  • SIRKULASI KORONER :Vs Dilatasi Pembuluh Darah KoronerKerja JantungTEKANAN DARAH :Stimulasi Pusat Vs. MotorStimulasi MiokardVs. DilatasiPerangsang Vagus

    Menaikkan Tekanan Darah (10 mm Hg)

  • OTOT POLOSTeofilinRelaksasi Otot Polos BronkusOTOT RANGKAKapasitas Kerja OtotDIURESIS :Teofilin : SebentarTeobromin : LamaKafein : Lemah

  • SEKRESI LAMBUNGSekresi Asam LambungEFEK METABOLIKKadar Asam Lemak Bebas Dalam DarahTOLERANSI Diuresis Gangguan Tidur S.S.P

  • FARMAKOKINETIKAbsorbsi Cepat Oral Rektal Parental

    Eliminasi : Hati

    Ekskresi : Urine

  • INTOKSIKASIMualMuntahKejangTeofilia

    Diatasi : Diazepam

  • INDIKASIAsma BronkialePenyakit ParuApneaSakit Kepala

    Minuman :Kopi- CoklatTeh- Cola

    KONTRA INDIKASI :AnakTukak PeptikHipertensi


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