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Towards Semantic Towards Semantic Interoperability Interoperability Framework for Custom Framework for Custom Orthopaedic Implants Orthopaedic Implants Manufacturing Manufacturing Milan Zdravkovic. Milan Zdravkovic. Miloš Stojkovic. Dragan Mišic. Miroslav Miloš Stojkovic. Dragan Mišic. Miroslav Trajanovi Trajanovi c c

Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

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Zdravkovic. M., Stojkovic, M., Misic, D., Trajanovic, M., 2012, Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing. 14th IFAC Symposium on Information Control Problems in Manufacturing (INCOM 2012), Track SS K4: Industrial Applications for Enterprise Models and Integration. May 23-25, 2012, Bucharest, Romania

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Page 1: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

Towards Semantic Interoperability Towards Semantic Interoperability Framework for Custom Orthopaedic Framework for Custom Orthopaedic

Implants ManufacturingImplants Manufacturing

Milan Zdravkovic. Milan Zdravkovic. Miloš Stojkovic. Dragan Mišic. Miroslav TrajanoviMiloš Stojkovic. Dragan Mišic. Miroslav Trajanovicc

Page 2: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

Page 3: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

Problem statementProblem statement

• Diagnosis and treatmentDiagnosis and treatment• EHR, CT scans, Domain knowledge,..EHR, CT scans, Domain knowledge,..

• Manufacturing of customized productsManufacturing of customized products• Key issuesKey issues

• Degree of customizationDegree of customization• Delivery timeDelivery time

• Barriers to customizationBarriers to customization• lack of efficiency of traditional manufacturing enterprise to lack of efficiency of traditional manufacturing enterprise to

handle low-series or one-of-a-kind production taskshandle low-series or one-of-a-kind production tasks• lack of efficiency in transfer of multi-disciplinary knowledge, lack of efficiency in transfer of multi-disciplinary knowledge,

required for the design of custom implantrequired for the design of custom implant

Page 4: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

Page 5: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

Proposed solutionProposed solution

• Virtual Breeding Environment / Virtual EnterprisesVirtual Breeding Environment / Virtual Enterprises• Qualified/certified manufacturing enterprises, Qualified/certified manufacturing enterprises,

technically coordinated by the broker (focal supplier to technically coordinated by the broker (focal supplier to clinical centers)clinical centers)

• Interoperable infrastructuresInteroperable infrastructures• Common infrastructureCommon infrastructure

• Models’ infrastructureModels’ infrastructure• Systems’ infrastructureSystems’ infrastructure

• Individual enterprises’ information systemsIndividual enterprises’ information systems

Page 6: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

Models infrastructureModels infrastructure

SimulationModel

ImplantModel

VEModel

VBEModel

ProcessModel

ProductionModel

CT scansGeneric

Parametric3D Model

ScaffoldModel

FixtureModelPre-operation

process model

Diagnosis

Page 7: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

ICT infrastructure and ICT infrastructure and interoperability issuesinteroperability issues

CLINICALINFORMATION

SYSTEM

SYSTEM FOR PRE-OPERATION PLANNING

Electronic Medical Record

OperationModel

SYSTEM FOR IMPLANTDESIGN

Product Models

VBE ITEnvironment

Clinical Centre IT Environment Shared

PACS RIS

DOMAINS

ORGANIZATIONAL

DATA

SYSTEMS

Page 8: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

Semantic interoperability issuesSemantic interoperability issues

• In single domain environmentIn single domain environment• Logical relations between the micro-steps carried out Logical relations between the micro-steps carried out

during the surgery and spatial features of the bones during the surgery and spatial features of the bones (location, arrangement) (CIS – PRE-OP-Sys)(location, arrangement) (CIS – PRE-OP-Sys)

• Logical relations between anesthesia planning and EHR Logical relations between anesthesia planning and EHR entities (CIS – PRE-OP-Sys)entities (CIS – PRE-OP-Sys)

• Logical relations between spatial features of the bones Logical relations between spatial features of the bones and implant design (CIS – IMPL-D-Sys)and implant design (CIS – IMPL-D-Sys)

• In cross-domain environmentIn cross-domain environment• Interoperability between IMPL-D-Sys and VBE systemsInteroperability between IMPL-D-Sys and VBE systems

Page 9: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

Semantic interoperability Semantic interoperability infrastructureinfrastructure

• Semantics layersSemantics layers• Local ontologiesLocal ontologies• Domain ontologiesDomain ontologies• Problem ontologies and Problem ontologies and

semantic applicationssemantic applications• Mapping ontologyMapping ontology

• Interoperability Interoperability servicesservices• Transformation serviceTransformation service• Semantic querying Semantic querying

serviceservice

EISDB

Localontology

EISDB

Localontology

Domainontology

Unifyingontology

Problemontology

Problemontology

Transformationservice

SemQueryingservice

Semanticapplication

Page 10: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

ProcessesProcesses

• Pre-operation planning servicePre-operation planning service• Design of the implant serviceDesign of the implant service• Sourcing, manufacturing and delivery of scaffold Sourcing, manufacturing and delivery of scaffold

and inner fixture products, engineered to orderand inner fixture products, engineered to order• Sourcing, implementation and delivery of services Sourcing, implementation and delivery of services

of digital reconstruction of traumatized bone and of digital reconstruction of traumatized bone and analysis of bio-mechanical properties of the analysis of bio-mechanical properties of the implantimplant

• Sourcing and implementation of the ethical Sourcing and implementation of the ethical committee review and delivery of review resultscommittee review and delivery of review results

Page 11: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

Process configuration in S-ISU Process configuration in S-ISU ontology (org view)ontology (org view)

custom-implant-engineering

has-process

VBE

Utility

Enterprise

Process

VE

has-member

owns-utility

facilitatesprecedes

implements-process

Impl-Manu-Cluster

Implant-Inc

BrokerSurgeon

CAD-IncBio-Inc

Metal-Inc

operation-planningimplant-design

plan-part-sourcing

plan-part-manufacturing

plan-part-deliveryplan-services-sourcing

plan-services-implementation

plan-services-delivery

source-scaffold

source-inner-fixture

make-scaffold

make-inner-fixture

source-digital-reconstruction

source-bio-mechanical-analysis

implement-digital-reconstruction

implement-bio-mechanical-analysis

deliver-bio-mechanical-analysis

deliver-digital-reconstruction

deliver-scaffold

deliver-inner-fixture

make-custom-implant

deliver-custom-implantsource-custom-

implant

Page 12: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

Resource configuration in S-ISU Resource configuration in S-ISU ontology (res view)ontology (res view)

SemApp

SCOR-Thread-Gen

Impl-Des-App

AppOntology

CIMPLANT-OWL

SCOR-CFG

MapOntology

IMPL-MAP

SCOR-FULL

DomOntology

EIS

Utility

EasySCOR-1

CIS-1

Op-Plan-App

OP-OWL

CAD-1

FEA-1

Ontology

Data-Container

File

FEA-Native-1

CAD-Native-1

EasySCOR-1

CIS-Database-1

FEA-Ont-1

LocOntology

CAD-Ont-1

SCOR-KOS OWL

CIS-Ont-1

uses-data-container

uses-data-container

uses-data-container

uses-data-container

explicits

explicits

explicits

explicits

imports imports imports importsimports

importsimports

uses-data-container

uses-data-container

uses-data-container

Database

Page 13: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

INCOM2012 - 14th IFAC Symposium on Information Control Problems in Manufacturing, Bucharest, Romania, May 23-25 2012

ConclusionsConclusions

• Contribution to inter-organizational Contribution to inter-organizational environment configurationenvironment configuration• Automated process configuration phaseAutomated process configuration phase• Automated exchange of information between Automated exchange of information between

systemssystems

Page 14: Towards Semantic Interoperability Framework for Custom Orthopaedic Implants Manufacturing

Towards Semantic Interoperability Framework for Towards Semantic Interoperability Framework for Custom Orthopaedic Implants ManufacturingCustom Orthopaedic Implants Manufacturing

Milan Zdravkovic. Milan Zdravkovic. Miloš Stojkovic. Dragan Mišic. Miroslav TrajanoviMiloš Stojkovic. Dragan Mišic. Miroslav Trajanovicc

Thank you for your attentionThank you for your attentionQ&AQ&A