Cover legend: Confocal images of retinal axons (grayand pink) and retinal ganglion cells (gray). Imageacquired by Denise Inman and pseudo colored by

Selva Baltan. For more information, see the article byBaltan et al. in this issue (pages 5644 –5652).

i This Week in The Journal

Brief Communications

5629 Inwardly Permeating Na Ions Generate the Voltage Dependence of Resurgent NaCurrent in Cerebellar Purkinje NeuronsTeresa K. Aman and Indira M. Raman

5724 Enhanced Endocannabinoid Signaling Elevates Neuronal Excitability in Fragile XSyndromeLonghua Zhang and Bradley E. Alger

5776 Astrocytes Impose Postburst Depression of Release Probability at HippocampalGlutamate SynapsesMy Andersson and Eric Hanse

Articles

CELLULAR/MOLECULAR

5508 The Phosphoinositide 3-Phosphatase MTMR2 Interacts with PSD-95 and MaintainsExcitatory Synapses by Modulating Endosomal TrafficHyun Woo Lee, Youngrim Kim, Kihoon Han, Hyun Kim, and Eunjoon Kim

� 5559 Selected SALM (Synaptic Adhesion-Like Molecule) Family Proteins Regulate SynapseFormationWon Mah, Jaewon Ko, Jungyong Nam, Kihoon Han, Woo Suk Chung,and Eunjoon Kim

5569 Cotrafficking of SV2 and Synaptotagmin at the SynapseJia Yao, Amy Nowack, Patricia Kensel-Hammes, Richard G. Gardner,and Sandra M. Bajjalieh

5617 Nerve Growth Factor-Regulated Emergence of Functional �-Opioid ReceptorsBihua Bie, Zhi Zhang, You-Qing Cai, Wei Zhu, Yong Zhang, Jaile Dai,Charles J. Lowenstein, Edward J. Weinman, and Zhizhong Z. Pan

5635 GSK3� Regulates Myelin-Dependent Axon Outgrowth Inhibition through CRMP4Yazan Z. Alabed, Madeline Pool, Stephan Ong Tone, Calum Sutherland,and Alyson E. Fournier

5653 Drosophila Neurexin IV Interacts with Roundabout and Is Required for RepulsiveMidline Axon GuidanceSwati Banerjee, Kevin Blauth, Kimberly Peters, Stephen L. Rogers,Alan S. Fanning, and Manzoor A. Bhat

The Journal of NeuroscienceApril 21, 2010 • Volume 30 Number 16 • www.jneurosci.org

5668 Cullin 5 Regulates Cortical Layering by Modulating the Speed and Duration ofDab1-Dependent Neuronal MigrationSergi Simó, Yves Jossin, and Jonathan A. Cooper

5677 Protein Kinase G Dynamically Modulates TASK1-Mediated Leak K� Currents inCholinergic Neurons of the Basal ForebrainHiroki Toyoda, Mitsuru Saito, Makoto Okazawa, Keiko Hirao, Hajime Sato,Haruka Abe, Kenji Takada, Kazuo Funabiki, Masahiko Takada, Takeshi Kaneko,and Youngnam Kang

DEVELOPMENT/PLASTICITY/REPAIR

5519 Brain Plasticity and Intellectual Ability Are Influenced by Shared GenesRachel G. H. Brans, Rene S. Kahn, Hugo G. Schnack, G. Caroline M. van Baal,Danielle Posthuma, Neeltje E. M. van Haren, Claude Lepage, Jason P. Lerch,D. Louis Collins, Alan C. Evans, Dorret I. Boomsma,and Hilleke E. Hulshoff Pol

5590 Fgfr2 Is Required for the Development of the Medial Prefrontal Cortex and ItsConnections with Limbic CircuitsHanna E. Stevens, Karen M. Smith, M. Elisabetta Maragnoli, Devon Fagel,Erzsi Borok, Marya Shanabrough, Tamas L. Horvath, and Flora M. Vaccarino

5767 A Forward Genetic Screen in Mice Identifies Sema3AK108N, which Bindsto Neuropilin-1 but Cannot SignalJanna Merte, Qiang Wang, Craig W. Vander Kooi, Sarah Sarsfield,Daniel J. Leahy, Alex L. Kolodkin, and David D. Ginty

5792 Target-Dependent Regulation of Neurotransmitter Specification and EmbryonicNeuronal Calcium Spike ActivityQian Xiao, Lin Xu, and Nicholas C. Spitzer

Π5802 Local Glutamate Level Dictates Adenosine A2A Receptor Regulation ofNeuroinflammation and Traumatic Brain InjuryShuang-Shuang Dai, Yuan-Guo Zhou, Wei Li, Jian-Hong An, Ping Li, Nan Yang,Xing-Yun Chen, Ren-Ping Xiong, Ping Liu, Yan Zhao, Hai-Ying Shen,Pei-Fang Zhu, and Jiang-Fan Chen

BEHAVIORAL/SYSTEMS/COGNITIVE

f 5481 Attentional Cueing at the Saccade Goal, Not at the Target Location, FacilitatesSaccadesAarlenne Z. Khan, Stephen J. Heinen, and Robert M. McPeek

5498 Separating Value from Choice: Delay Discounting Activity in the LateralIntraparietal AreaKenway Louie and Paul W. Glimcher

5533 The ON Pathway Rectifies the OFF Pathway of the Mammalian RetinaZhiyin Liang and Michael A. Freed

5603 Social Interactions Determine Postural Network Sensitivity to 5-HTDaniel Cattaert, Jean-Paul Delbecque, Donald H. Edwards,and Fadi A. Issa

5713 Ventral Tegmental Area Leptin Receptor Neurons Specifically Project to and RegulateCocaine- and Amphetamine-Regulated Transcript Neurons of the Extended CentralAmygdalaRebecca L. Leshan, Darren M. Opland, Gwendolyn W. Louis, Gina M. Leinninger,Christa M. Patterson, Christopher J. Rhodes, Heike Munzberg,and Martin G. Myers Jr

5730 Striatal Dopamine Modulates Basal Ganglia Output and Regulates SocialContext-Dependent Behavioral Variability through D1 ReceptorsArthur Leblois, Benjamin J. Wendel, and David J. Perkel

5781 Presynaptic and Postsynaptic Mechanisms of Synaptic Plasticity and Metaplasticityduring Intermediate-Term Memory Formation in AplysiaIgor Antonov, Eric R. Kandel, and Robert D. Hawkins

NEUROBIOLOGY OF DISEASE

5489 Molecular Characterization of Mutations That Cause Globoid Cell Leukodystrophyand Pharmacological Rescue Using Small Molecule Chemical ChaperonesWing C. Lee, Dongcheul Kang, Ena Causevic, Aimee R. Herdt,Elizabeth A. Eckman, and Christopher B. Eckman

5525 Decaffeinated Coffee and Nicotine-Free Tobacco Provide Neuroprotection inDrosophila Models of Parkinson’s Disease through an NRF2-Dependent MechanismKien Trinh, Laurie Andrews, James Krause, Tyler Hanak, Daewoo Lee,Michael Gelb, and Leo Pallanck

5544 Evidence from Computer Simulations for Alterations in the Membrane BiophysicalProperties and Dendritic Processing of Synaptic Inputs in Mutant SuperoxideDismutase-1 MotoneuronsSherif M. ElBasiouny, Julien Amendola, Jacques Durand, and C. J. Heckman

5579 Defective cAMP Generation Underlies the Sensitivity of CNS Neurons toNeurofibromatosis-1 HeterozygosityJacquelyn A. Brown, Scott M. Gianino, and David H. Gutmann

5644 Metabolic Vulnerability Disposes Retinal Ganglion Cell Axons to Dysfunction in aModel of Glaucomatous DegenerationSelva Baltan, Denise M. Inman, Camelia A. Danilov, Richard S. Morrison,David J. Calkins, and Philip J. Horner

� 5690 High-Frequency Network Activity, Global Increase in Neuronal Activity, andSynchrony Expansion Precede Epileptic Seizures In VitroPremysl Jiruska, Jozsef Csicsvari, Andrew D. Powell, John E. Fox,Wei-Chih Chang, Martin Vreugdenhil, Xiaoli Li, Milan Palus, Alejandro F. Bujan,Richard W. Dearden, and John G. R. Jefferys

5702 Disrupted Transforming Growth Factor-� Signaling in Spinal and Bulbar MuscularAtrophyMasahisa Katsuno, Hiroaki Adachi, Makoto Minamiyama, Masahiro Waza,Hideki Doi, Naohide Kondo, Hiroyuki Mizoguchi, Atsumi Nitta,Kiyofumi Yamada, Haruhiko Banno, Keisuke Suzuki, Fumiaki Tanaka,and Gen Sobue

5744 A Missense Mutation of the Gene Encoding Voltage-Dependent Sodium Channel(Nav1.1) Confers Susceptibility to Febrile Seizures in RatsTomoji Mashimo, Iori Ohmori, Mamoru Ouchida, Yukihiro Ohno,Toshiko Tsurumi, Takafumi Miki, Minoru Wakamori, Shizuka Ishihara,Takashi Yoshida, Akiko Takizawa, Megumi Kato, Masumi Hirabayashi,Masashi Sasa, Yasuo Mori, and Tadao Serikawa

5754 SOCS3-Mediated Blockade of JAK/STAT3 Signaling Pathway Reveals Its MajorContribution to Spinal Cord Neuroinflammation and Mechanical Allodynia afterPeripheral Nerve InjuryElisa Dominguez, Annie Mauborgne, Jacques Mallet, Mathieu Desclaux,and Michel Pohl

Erratum: In the article “Population Coding of Reward Magnitude in theOrbitofrontal Cortex of the Rat” by Esther van Duuren, Jan Lankelma, and CyrielM. A. Pennartz, which appeared on pages 8590 – 8603 of the August 20, 2008,issue, the authors would like to extend the original Acknowledgements to includeFrancisco A. Nieto Escamez, Ruud N. J. M. A. Joosten, Rein Visser, and AntoniusB. Mulder for helping to collect the single-unit firing rate data that were originallydescribed in the study by van Duuren et al. (2007) [van Duuren E, Escamez FA,Joosten RN, Visser R, Mulder AB, Pennartz CM (2007) Neural coding of rewardmagnitude in the orbitofrontal cortex of the rat during a five-odor olfactorydiscrimination task. Learn Mem 14:446-456], and which provided a primarydatabase for the novel analyses and results presented in the study by vanDuuren et al. (2008).

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