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http://www.slideshare.net/holcombea/
Reproducibility, Open access,
& Open science
9 September, 2015 Open Knowledge Foundation Australia, Melbourne
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Rule among early-stage venture capital firms that “at least 50% of published studies, even those in top-tier academic journals, can't be repeated with the same conclusions by an industrial lab” - Prinz, Schlange, & Asadullah. Nature Rev. Drug Discov. 10, 712 (2011)
Bayer HealthCare :only about 25% of published preclinical studies could be validated to the point at which projects could continue
Amgen Fifty-three papers were deemed ‘landmark’ studies (see ‘Reproducibility of research findings’)... scientific findings were confirmed in only 6 (11%) cases
Academic knowledge is boxed in by expensive journals.
Scientist meets Publisher
http://www.youtube.com/watch?v=GMIY_4t-DR0
+ Monopoly = Profit maximisation
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US$11,000 per year; $300 for a single issue
$
Profit Company Industry
10% BMW automobiles
23% Rio Tinto mining
25% Google search
29% Apple premium computing
35% Springer scholarly publishing
37% Elsevier scholarly publishing
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adding valueinnovative
http://shiny.retr0.me/journal_costs/
https://alexholcombe.wordpress.com/2015/05/04/four-reasons-to-oppose-the-use-of-elseviers-services-for-the-medical-journal-of-australia/
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How open science wins Cultural change
• Early adopters
• Researcher training
• Advocacy, lobbying
• Journals strengthen sharing policies
Tech work at grassroots • Altmetrics
• Streamlining repositories
• Software for reproducible research
CC-BY Alex Holcombe
Research funders ramp up requirement that code, data be posted
http://aoasg.org.au/2015/08/31/going-beyond-the-published-article-how-open-access-is-just-a-start/
Article borders dissolve: Data, commentary, replication, re-‐analyses
