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Dr Tin Myo Han Department of Community Dentistry Kulliyyah of Dentistry, International Islamic University, Malaysia

4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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Showing relationship between Epidemiology, Bio-statistics and Dental public health activities for 4th year dental students to get more understanding on why they need to do students' research project and how to apply it!

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Page 1: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Dr Tin Myo Han

Department of Community Dentistry

Kulliyyah of Dentistry, International Islamic University, Malaysia

Page 2: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Epidemiology Biostatistics Public Health/ Dental Public

Health

25/9/2014

Page 3: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

25/9/2014

IIUM

Page 4: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Epidemiology of Dental Caries & Periodontal Disease - Magnitude (prevalence of Dental Caries & PD) - Analysis of Epidemiological Data: *Comparison between clinic’s register and community survey - Applicability of Epidemiological Data analysis

25/9/2014

• Role of Biostatistics in investigation of more Periodontal Cases Findings in Community

• Public Health Activities: -Prevention & Promotion of Oral Health: Action Plan to reduce Periodontal Disease burden

EPIDEMIOLOGY

Bio-stat

• Assignment for Students

DPH

Page 5: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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A public dental Clinic

(KK-Gigi, Kuantan)

In accordance with clinic’s register,

Period : from 1st January 2013 to 31st December 2013

Total dental Patients : 500 patients

-Adult dental caries : 220 cases

-Periodontal diseases : 110 cases

-Pediatric dental caries : 70 cases

-Dentures : 20 cases

- Dental check-up : 30 cases

- Oral surgical cases : 45 cases

- Orthodontics & other : 5 cases

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A Community Oral

Health Survey

- Community dentistry department, KOD, IIUM,

conducted a community survey in Kuantan to

estimate the magnitude of common oral health

problems in 2013

-Total 350 dental caries cases

-250 periodontal cases

-25 newly diagnosed oral ulcer cases and

-15 dental injury cases (old + new)

- were identified from 5000 persons under the study

Page 7: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Epidemiology of Dental Caries & Periodontal Disease - Magnitude (prevalence of Dental Caries & PD) - Analysis of Epidemiological Data: *Comparison between clinic’s register and community survey - Applicability of Epidemiological Data analysis

25/9/2014

• Role of Biostatistics in investigation of more Periodontal Cases Findings in Community

• Public Health Activities (Plan): -Prevention & Promotion of Oral Health: Action Plan to reduce burden of Periodontal Disease

EPIDEMIOLOGY

Bio-stat

DPH

• Assignment for Students

Page 8: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

25/9/2014

Q 1. How to measure magnitude of Dental Caries & PD (epidemiological measurement)? ( Rate,Ratio, Proportion, Prevalence and Incidence)? Q 2. Which epidemiological measurement will be used to compare these epidemiological data between the public dental clinic and the community survey? Q3. What is your conclusion on the epidemiological data analysis ? Q4. What should you do to get more understanding on the situation ? Why ?

Page 9: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Public Dental Clinic Community Survey

Proportion of dental caries (adult + Child) in 2013 = ( 220 +70)/500 *100 = 58% of patients /year Proportion of PD in 2013 = 110/500 *100 = 22% of patients/year Ratio of Dental Caries

and Periodontal cases = 290:110 = 29:11 ~ 3:1

Prevalence of Dental caries ( 2013)

= 70 cases per 1000 population

Prevalence of PD ( 2013) = 50 cases per 1000 population

25/9/2014

Page 10: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Public Dental Clinic Community Survey

Proportion of dental caries (adult + Child) = ( 220 +70)/500 *100 = 58% of patients Proportion of PD = 110/500 *100= 22% of patients

Prevalence of Dental caries ( 2013)

= 70 cases per 1000 population

Prevalence of PD ( 2013) = 50 cases per 1000

population

25/9/2014

Prevalence Dental Caries = 58% or 580 cases per 1000 patients per year

Prevalence of PD = 220 cases per 1000 patients per year

Ratio of Dental Caries & PD

= 290:110 (or) 58 :22 = 29:11 ~ 3:1

Ratio of Dental Caries & PD

= 350:250 (or) 70:50

= 7:5 =1.4 :1~ 1.5 :1

RATIO

Page 11: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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Q 1. How to measure magnitude of Dental Caries & PD (epidemiological measurement)? ( Proportion, Prevalence and Ratio)? Q 2. Which epidemiological measurement will be used to compare these epidemiological data between the public dental clinic and the community survey ? Q3. What is your conclusion on the epidemiological data analysis ? Q3. What should you do to get more understanding on the situation ? Why ?

Page 12: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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“We have more dental caries cases than PD! (3:1)” ……” Prevalence of dental caries in the clinic higher than that of PD” ! (Clinic attendance rate)

“In our community survey also more dental caries cases than PD! (1.4:1)” …”Prevalence of dental caries is also higher than that of PD in community”…

..” However, PD cases were found more in the community survey than clinics “ ……………

(3:1) vs (1.4:1)

Page 13: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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Q 1. How to measure magnitude of Dental Caries & PD (epidemiological measurement)? ( Proportion, Prevalence and Ratio)? Q 2. Which epidemiological measurement will be used to compare these epidemiological data between the public dental clinic and the community survey ? Q3. What is your conclusion on the epidemiological data analysis ? Q4. What should you do to get more understanding on the situation ? Why ?

Page 14: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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..” However, PD cases were found more in the community survey than clinics “ ……………

(3:1) vs (1.4:1)

..” We want to know why PD cases were found more in the community survey than in the clinic “

“ Which factors are influencing on it?

“Epidemiological question (or) starting point for Epidemiological study “

Page 15: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

1. Trend study 2. Community diagnosis 3. Health services evaluation 4. To know the individual risks and chances 5. Syndrome identification 6. Completing the clinical picture 7. Searching for causes / risk factors for

establishing causal relationship (New diseases or existing diseases)

15

Page 16: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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Why PD cases were found more in the community survey than in the clinic“ “ Which factors are influencing on it?

Page 17: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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TIME

PLACE PERSON

Agent

Host Environment

Causation Triads Distribution Triads

MOT

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TIME

PLACE PERSON

Agent

Host Environment

Causation Triad Distribution Triad

Page 19: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Epidemiology of Dental Caries & Periodontal Disease - Magnitude (prevalence of Dental Caries & PD) - Analysis of Epidemiological Data: *Comparison between clinic’s register and community survey - Applicability of Epidemiological Data analysis

25/9/2014

• Role of Biostatistics in investigation of more Periodontal Cases Findings in Community

• Public Health Activities (Plan): -Prevention & Promotion of Oral Health: Action Plan to Combat Periodontal Disease

EPIDEMIOLOGY

Bio-stat

DPH

• Assignment for Students

Page 20: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

“Role of Biostatistics in Epidemiological Investigation “

25/9/2014

Page 21: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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Community Survey: December 1st -31st,2013

Clinic: Klinik Kasiharan Balok

“Distribution of disease (Distribution Triad)”

Clinic register:1st January to December 31st,2013

Community: Sungi Lembing

Survey: 250 PD cases

/5000 person

Clinic: 110 PD cases/500

Patients

TIME PERSON

PLACE

Page 22: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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Community Survey: December 1st -31st,2013

“Distribution Triad: TIME

Balok Clinic register: 1st January to December 31st,2013

Distribution: endemic pattern Distribution: epidemic/outbreak pattern

Page 23: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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“Distribution Triad: PLACE

Residence:

Out of 110,

-108 patients

(Balok community)

-2 patients (Beserah)

•* *

* * •* *

* *

*

KK Balok Dental Clinic Community Survey: December 1st -31st,2013

Residence:

Out of 250,

-108 cases

(Sungai Lembing )

-142 patients

(Flood Relief Center

Sungai Lembing)

•* *

* *

•* *

* *

•* *

* *

Epidemiological Mapping

Page 24: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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Community Survey: December 1st -31st,2013

“Distribution of disease (Distribution Triad)”

TIME

3rd to 7th December 2013

Page 25: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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“Distribution Triad: PERSON (Age,Gender,Race,Edu & Occupation)

Age Groups

Periodontal Cases

Significant test & “p” Value

Community Survey Sungai Lembing

(n=250) n(%)

Public Dental Clinic (Balok) (n=110)

n(%)

< 20 years 10 (4) 6 (6)

X2 test “p” >0.05

21-40 years 63(25) 28 (25)

41-60 years 127(51) 61 (55)

>60 years 50(20) 15(14)

Total 250 110

Summary descriptive statistics

Minimum = 18 Maximum = 67 Mean(±SD )= 43(± 5.1)

Minimum =17 Maximum = 65 Mean(±SD )= 44(± 4.9)

“ t” Test “p” >0.05

Page 26: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Based on distribution triad analysis,

- unexpected increase in number of PD cases was found 2 weeks after Flood (time) - 56.8%(146/250) of them were from Flood relief

centers (place) - 51% ( 127/250) were 41-60 years old ( Person) - Thus, more PD cases in Community survey may be more occurrence of PD among Persons from flood relief centers

25/9/2014

Hypothesis of Distribution

Page 27: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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AGENT

ENVIRONMENT

HOST

Page 28: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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AGENT

Ref: Basic Epidemiology assignment answered by dental students (2014-2015)

Page 29: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

29

?P

D K

no

wle

dg

e

Diet/Sweet

?S

tres

s

AGENT

Most likely causes of PD in Community Survey in Kuantan 2013

Page 30: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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Risk factors

Periodontal Cases Significant

test & “p” Value

Community Survey Sungai Lembing

(n=250) n(%)

Public Dental Clinic (Balok) (n=110)

n(%)

Yes No Yes No

X2 test “p”

Poor Oral Hygiene 67% 33% 42% 58%

Stress (+) 70% 30% 30% 70%

DM (+) 47% 53% 27% 73%

-Significant Association between “(Poor oral hygiene & PD)”

(Stress & PD ) were found in community survey

Page 31: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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HOST

Page 32: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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HOST

More severe PD cases were seen among:

- more than 41 years old (60%),

- female (67%) and

- DM patients ( 76%)

Page 33: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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ENVIRONMENT

Macro environment : -weather (flood) -Social status ( flood relief centre) - OH materials and supply -Other factors

Micro environment : -Oral flora changes because of Oral hygiene practices , Stress, Underlying Medical disease (DM)

Page 34: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Based on causal triad analysis, Causes of more PD cases

were :

- Poor OH practices , Stress, and underlying medical

disease (DM) (Agent)

- Severe PD were above 41 years old, female, DM (Host)

- flood in Kuantan and changing oral flora (environment)

25/9/2014

Causal Hypothesis

Page 35: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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EPIDEMIOLOGY

Descriptive Hypothesis

Descriptive

Statistics

Age , sex,

occupation,

( Minimal ,

Maximum age,

Frequency ( %)

Causal Hypothesis

Inferential

Statistics

Significant Association

b/t age, sex , risk factors & occurrence of disease

( X2, ANOVA)

Page 36: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Epidemiology of Dental Caries & Periodontal Disease - Magnitude (prevalence of Dental Caries & PD) - Analysis of Epidemiological Data: *Comparison between clinic’s register and community survey - Applicability of Epidemiological Data analysis

25/9/2014

• Role of Biostatistics in investigation of more Periodontal Cases Findings in Community

• Public Health Activities (Plan): -Prevention & Promotion of Oral Health: Action Plan to reduce burden of Periodontal Disease

EPIDEMIOLOGY

Bio-stat

DPH

• Assignment for Students

Page 37: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Prevention & Promotion of Oral Health: Action Plan to reduce burden of

Periodontal

25/9/2014

Page 38: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Primary prevention : -Screening PD among community & risk populations

(self-reported questionnaires & professional screening (BPE)

Secondary prevention : - Early diagnosis and prompt treatment to reduce loss

of teeth ( avoidable ) Tertiary prevention (Rehabilitation) : Quality of life of PD patients!

25/9/2014

Page 39: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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Page 40: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Oral health care in unusual situation ( eg. flood) :

25/9/2014

Page 41: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

More

PD cases in Community survey

Public Dental Clinic vs Community

Survey

(Case findings of caries and PD)

( 270 vs 350 in dental caries) &

(110 vs 250 in PD)

Dental Caries vs Periodontal Disease

( 3:1 in Public Clinics & 1.4 :1 in Community survey

25/9/2014

Page 42: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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In the scenario, Ratio of Dental Caries &

PD, Dental caries ceases are higher than PD in both private dental clinics data and community survey.

Q-1 : Give reasons for attending less PD at

public dental clinics and finding less PD in community survey comparing with dental caries?

Dental Caries vs Periodontal Disease?

Page 43: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Answers 1:

Nature of diseases (Overt caries vs hidden PD

cases)

Knowledge of patients on PD

Awareness of patients on PD & Dental services

Oral health seeking behavior ( peer )

Other unknown factors (!!! Research)

25/9/2014

Page 44: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

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In the scenario, more Dental caries and PD cases were found in community survey than public dental clinic

Q-2 : Give reasons for finding more Dental

caries and PD cases in community survey?

Community survey data vs Public dental clinic data?

Page 45: 4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) sept 25th 2014(edited)

Answers 2:

Active case finding (community survey) vs passive case

finding ( public dental clinic)

Iceberg phenomenon

Socio-economic and cultural factors

( communication, financial support, value and norm on

oral health)

Knowledge of patients on OH care & services

Other factors (unknown )!! Research

25/9/2014

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25/9/2014 47

“ Oral Health Manpower & Trends of common oral health problems in

“MALAYSIA ” comparing with Japan, & Singapore )

4th Year Dental Students ( 2014-2015)