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2009 H1N1 Info gathered by Mona Youss

swine flu , mexican ? 2009 Novel H1N1 pandemic !

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What we know so far... from WHO, CDC, Rhiza lab flu tracker

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Page 1: swine flu , mexican ? 2009 Novel H1N1 pandemic !

2009 H1N1

Info gathered by Mona Youssef

Page 2: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Study has shown virus to be different from the normally circulating North American pig virus.

It has two genes from flu viruses that normally circulate in pigs in Europe and Asia , avian genes and human genes.

"quadruple reassortant" virus

How is it then that it made its first appearance in Mexico and the US?

Page 3: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Charecteristics

• Influenza virus can survive on environmental surfaces and remain infectious for up to 2-8 hours after being deposited on the surface.

• Virus is destroyed by:o heat 75-100 degrees Celcius.o chemical germicides: chlorine, hydrogen peroxide, detergents

(soap), iodophors (iodine-based antiseptics), and alcohols.

*wipes or gels with alcohol in them should be rubbed into hands

until they are dry.

A person can sneeze on someone’s luggage in an airport, and start an outbreak in a country without even entering it!

Page 4: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Swine flu virus(Not novel H1N1)

• Like all influenza viruses, swine flu viruses change constantly.

• Pigs can be infected by avian influenza and human influenza viruses as well as swine influenza viruses.

• When influenza viruses from different species infect pigs, the viruses can reassort (i.e. swap genes) and new viruses that are a mix of swine, human and/or avian influenza viruses can emerge.

• Over the years, different variations of swine flu viruses have emerged. There are currently four main influenza type A virus subtypes that have been isolated in pigs: H1N1, H1N2, H3N2, and H3N1.

• Most of the recently isolated influenza viruses from pigs have been H1N1 viruses.

H3 subtypes infect older population and tend to be more severe.

Page 5: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Drinking water?• No completed research for novel H1N1 virus.

• Free chlorine levels typically used in drinking water treatment are adequate to inactivate highly pathogenic H5N1 avian influenza.

• It is likely that other influenza viruses such as novel H1N1 would also be similarly inactivated by chlorination.

Page 6: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Swimming Pools• No completed research for novel H1N1 virus.

• Free chlorine levels recommended by CDC (1–3 parts per million [ppm or mg/L] for pools and 2–5 ppm for spas) are adequate to disinfect avian influenza A (H5N1) virus.

• It is likely that other influenza viruses such as novel H1N1 would also be similarly inactivated by chlorination.

Page 7: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Dealing with the Deceased

• Transport of deceased persons does not require any additional precautions when bodies have been secured in a transport bag. Hand hygiene should be performed after completing transport.

• For deceased persons with confirmed, probable, or suspect novel influenza A (H1N1):o limit contact with the body in health care settings to close family

memberso Direct contact with the body is discouragedo Necessary contact may occur as long as hands are washed

immediately with soap and water.

NO need for mass burials yet….

Page 8: swine flu , mexican ? 2009 Novel H1N1 pandemic !

• Autopsy:o Standard Precautions.o Additional respiratory protection is needed procedures that

generate aerosols (e.g., use of oscillating saws). o minimize the number of personnel participating in post mortem

examinations.o Follow standard safety procedures for preventing percutaneous

injuries during autopsy.

Page 9: swine flu , mexican ? 2009 Novel H1N1 pandemic !

He says ice-cream made

him feel better, and Thank God

has now recovered full health.But the rest of the planet has a quick –

paced pandemic marching

on….'Patient Zero' in Swine Flu Outbreak Identified as 5-Year-Old Mexican Boy:

Edgar Hernandez

Page 10: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Timeline

Page 11: swine flu , mexican ? 2009 Novel H1N1 pandemic !

April 23 : S-OIV (swine origin influenza virus) confirmed, same strain detected in two California children as in Mexico. PAHO informed of Mexico cluster of S-OIV

MidMarch: La Gloria,Veracruz, 60% of the town's population is sickened by a respiratory illness of unknown provenance.

Mexico

April 16 : Mexico Authorities notify the PAHO (Pan American Health Organization) of the atypical pneumonia.

Canadian labs

Page 12: swine flu , mexican ? 2009 Novel H1N1 pandemic !

WHO• April 24: 2009 H1N1 first disease outbreak notice.

• April 25: WHO Director General declares a formal• “Public health emergency of international concern”

• April 27: “containment of the outbreak is not feasible” pandemic alert raised from phase 3 to phase 4.

• April 29: phase 4 to phase 5.

• June 11: phase 5 to phase 6.

During this time interim, the WHO was vastly criticized for not announcing

phase 6

Page 13: swine flu , mexican ? 2009 Novel H1N1 pandemic !

WHO Report 95 AFFECTED COUNTRIES

Nothing’s holding this virus back…….!!!

Page 14: swine flu , mexican ? 2009 Novel H1N1 pandemic !

keyword

A pandemic means an epidemic of an infectious disease, that spreads throughout a large number of people and can spread worldwide.

A pandemic begins when: there is person-to-person sustained transmission on multiple continents.

Page 15: swine flu , mexican ? 2009 Novel H1N1 pandemic !

The World Health Organization uses a six stage phase for alerting the general public to an outbreak

Page 16: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Phase 1 – animal to animal transmission.

Phase 2 – an animal influenza virus is capable of human infection.

Phase 3 - small outbreaks among close populations but

not through human to human contact.

Phase 4 - Human to human transmission

Phase 5 - spread across two countries or more in one of the WHO regions (continents).

Phase 6 – spread across two countries or more in one of the WHO regions plus spread to another WHO region.

Page 17: swine flu , mexican ? 2009 Novel H1N1 pandemic !

W.H.O. identifies the following six epidemiological sub-regions.  

- African Region- Eastern Mediterranean Region- European Region- Region of the Americas- South-East Asian Region- Western Pacific Region

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Even an island in the middle of the ocean isn’t out of its reach….

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In one week, the United Nations agency raised the alert level twice,

from phase 3 to phase 5, in response to the sustained transmission

of H1N1 in Mexico and the United States.

Graveness of the situation

Page 28: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Country Cumulative total

Newly confirmed since the last reporting period

Cases Deaths

Cases Deaths

Country Cumulative total

Newly confirmed since the last reporting period

Cases Deaths

Cases Deaths

Country Cumulative total

Newly confirmed since the last reporting period

Cases Deaths

Cases Deaths

Argentina 918 4 185 3

Australia 2199 0 87 0

Austria 8 0 1 0

Bahamas 2 0 0 0

Bahrain 12 0 0 0

Barbados 4 0 1 0

Belgium 19 0 0 0

Bermuda, UKOT 1 0 0 0

Bolivia 11 0 0 0

Brazil 96 0 17 0

British Virgin Islands, UKOT 1 0 0 0

Bulgaria 2 0 0 0

Canada 4905 12 856 5

Cayman Islands, UKOT 4 0 0 0

Chile 3125 2 790 0

China 519 0 137 0

Colombia 60 1 7 0

Costa Rica 149 1 0 0

Cuba 15 0 8 0

Cyprus 1 0 0 0

Czech Republic 5 0 1 0

Denmark 22 0 7 0

Dominica 1 0 0 0

Dominican Republic 93 1 0 0

Ecuador 86 0 0 0

Egypt 29 0 3 0

El Salvador 160 0 35 0

Estonia 5 0 1 0

Finland 13 0 1 0

France 131 0 13 0

French Polynesia, FOC 1 0 0 0

Martinique, FOC 1 0 0 0

Germany 238 0 43 0

Greece 31 0 8 0

Guatemala 153 1 25 0

Honduras 108 0 8 0

Hungary 7 0 3 0

Iceland 4 0 0 0

India 30 0 0 0

Ireland 16 0 4 0

Israel 219 0 67 0

Italy 88 0 16 0

Jamaica 14 0 2 0

Japan 690 0 24 0

Jordan 2 0 0 0

Korea, Republic of 84 0 19 0

Kuwait 18 0 0 0

Laos 1 0 1 0

Lebanon 12 0 1 0

Luxembourg 2 0 0 0

Malaysia 23 0 6 0

Mexico 7624 113 1383 5

Morocco 8 0 5 0

Netherlands 87 0 19 0

Netherlands Antilles, Curaçao * 3 0 2 0

Netherlands Antilles, Sint Maarten 1 0 1 0

New Zealand 216 0 89 0

Nicaragua 144 0 26 0

Norway 17 0 4 0

Oman 3 0 3 0

Panama 272 0 0 0

Papua New Guinea 1 0 1 0

Paraguay 27 0 2 0

Peru 141 0 29 0

Philippines 311 0 118 0

Poland 7 0 0 0

Portugal 5 0 2 0

Qatar 3 0 0 0

Romania 18 0 2 0

Russia 3 0 0 0

Samoa 1 0 0 0

Saudi Arabia 22 0 5 0

Singapore 77 0 28 0

Slovakia 3 0 0 0

South Africa 1 0 1 0

Spain 512 0 13 0

Sri Lanka 1 0 0 0

Suriname 11 0 11 0

Sweden 43 0 6 0

Switzerland 27 0 0 0

Thailand 518 0 208 0

Trinidad and Tobago 18 0 13 0

Turkey 20 0 4 0

Ukraine 1 0 0 0

United Arab Emirates 2 0 1 0

United Kingdom 1752 1 291 0

Isle of Man, Crown Dependency 1 0 0 0

Jersey, Crown Dependency 1 0 0 0

United States of America 17855 44 0 0

Uruguay 36 0 0 0

Venezuela 60 0 15 0

Viet Nam 27 0 0 0

West Bank and Gaza Strip 5 0 3 0

Yemen 4 0 3 0

Grand Total 44287 180 4667 13

19/6/2009 19/6/2009

Page 29: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Australia 2199 0 87 0

Chile 3125 2 790 0

Egypt 29 0 3 0

Mexico 7624 113 1383 5

United States of America 17855 44 0 0

Grand Total 44287 180 4667 13

Country (19/6/2009) Cumulative total Newly confirmed since the last reporting period (17/6)

Cases Deaths Cases Deaths

Countries of origin.

Mixing of NH1N1 with seasonal flu virus could result in a strain resistant to tamiflu(NH1N1 is already resistant

to other antivirals

Mixing with H5N1 could produce strains capable of human to human transmission(Death toll of H5N1 is app. 66%)

Page 30: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Consequences of a declaration of a full

pandemic

Institution of pandemic response plans, which may include measures affecting hospitals, schools or public events.

Provision of support for developing countries including: drugs, diagnostic tests, and medical staff

WHO would be expected to make an announcement to specify whether manufacturers should switch from making seasonal to pandemic flu vaccines.

Page 31: swine flu , mexican ? 2009 Novel H1N1 pandemic !

June 5 CDC Report:

Testing•CDC has developed a PCR diagnostic test kit •Distributed test kits throughout U.S. nation as well as internationally.

Vaccine •CDC has isolated the new H1N1 virus, made a candidate vaccine virus that can be used to create vaccine. (Novartis manufactures first vaccine June 11 2009)

Strategic National Stockpile•CDC has deployed 25 percent of the supplies in the Strategic National Stockpile (SNS) to all states in the continental United States and U.S. territories. •This included antiviral drugs, personal protective equipment, and respiratory protection devices.

Page 32: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Previous Global Pandemics

Page 33: swine flu , mexican ? 2009 Novel H1N1 pandemic !

1918 - Spanish Flu (originated in birds).

First hit soldiers in Europe during World War I, as their immune systems were weakened by war.

The mortality rate was highest between 20 to 50 year olds. There was never any vaccine developed, after about 18 months, the virus seemed to just disappear.

The final death toll was written as 40 million people worldwide.

Soldiers whose

immunity was

weakened by war.

Many of the victims who have died in Mexico have been young and otherwise healthy. society's healthiest demographic

Page 34: swine flu , mexican ? 2009 Novel H1N1 pandemic !

1957 - Asian FluThis flu started in birds in Asia.

In September schools and public places started closing in an effort to contain the virus.

In December the virus started to subside, but reappeared in January.

over two million people died

Reappeared

Page 35: swine flu , mexican ? 2009 Novel H1N1 pandemic !

1968 - The Hong Kong Flu

This is the mildest pandemic It was first found in the early months of 1968 in Hong Kong, and was declared a global pandemic by December.

Children were out of school and were therefore not able to spread it as much.

It made a mild reappearance in 1970 and 1972.

it claimed about a million lives

Reappeared…!!! Seasonal influenza normally claims app. ¼ to ½ a million lives yearly.

Page 36: swine flu , mexican ? 2009 Novel H1N1 pandemic !

What we do know

Page 37: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Disease spectrum ranges from very mild self-limited disease to Death.

 Novel H1N1 virus tends to affect younger people just like the seasonal H1N1.

 

Novel H1N1 spreads just as easily as regular winter flu.

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The southern hemisphere is about to enter winter, when seasonal flu cases normally spike.

We have to be prepared for changes in:

• The amount of illness• The severity of illness• The characteristics of the virus• The reactions of our communities

Early evidence in the southern hemisphere points to novel H1N1 potentially crowding out the seasonal flu viruses which is something that's been seen in previous pandemics.

Page 39: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Seasonal flu vaccine production is to continue as is, in an attempt to reduce the chances of the viruses mingling together in the same environment.

Simultaneous circulation of the seasonal flu strains with the Novel H1N1 raises the possibility of mixing of the strains.

Seasonal H1N1 virus that we've had this past year is resistant to Tamiflu.

Page 40: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Characteristics of reported cases of influenza A(H1N1) by country

Of note , the prevailing clinical picture in other countries has

been GIT related.

Page 41: swine flu , mexican ? 2009 Novel H1N1 pandemic !

There are several important limitations about the data that must be considered:

countries are using different surveillance methods and case definitions

most countries are at an early stage of disease spread ,a complete picture of the epidemiological and clinical characteristics of the H1N1 virus is unattainable.

Caution must be exercised in interpreting information such as age as it may reflect patterns of travel or the occurrence of outbreaks in special settings such as schools.

the early estimates of important epidemiological parameters such as incubation period and attack rate have been derived from a limited number of settings such as households and schools and may not be broadly applicable.

although Mexico and the United States have reported deaths among persons with confirmed H1N1 infection, it is too early to get a reliable estimate of the case fatality ratio.

Additional studies are needed to assess risk factors for infection with the H1N1 virus as well as the severity of illness.

Page 42: swine flu , mexican ? 2009 Novel H1N1 pandemic !

VACCINE

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A review of 2009 production status for northern hemisphere seasonal vaccine indicates that:

Industry plans to produce approximately 480 million doses of trivalent seasonal vaccine in 2009.

Of this, 350 and 430 million doses will be available by 30 June and 31 July 2009, respectively.

For influenza A (H1N1), it is estimated that up to 4.9 billion doses could be produced over a 12‐month period IF there is initiation of a full‐scale production. In this situation, there is a potential access for the UN of supplies of up to 400 million doses.

A lot of Ifs……..

Page 44: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Currently available data indicate that:

• Immunization with recent or shortly to be available trivalent seasonal vaccine is unlikely to provide public health benefits in terms of protection against influenza A (H1N1).

• Unknowns: optimal antigen content, the required number of doses, the required intervals between doses and the interchangeability of different products is currently unknown for

influenza A (H1N1) vaccines. the safety profile

Page 45: swine flu , mexican ? 2009 Novel H1N1 pandemic !

After considering the following issues:1. the need for any recommendation to balance both risks and benefits,2. the current uncertainty about the severity of influenza A (H1N1) illness,3. the readiness of vaccine seed strains and reagents for large scale vaccine ‐

production,4. the current status of production of seasonal vaccine for the Northern hemisphere, 5. The risks associated with a premature cessation of seasonal vaccine production,

Page 46: swine flu , mexican ? 2009 Novel H1N1 pandemic !

•two doses of vaccine may be needed to induce adequate protection, as the global population is immunologically naïve to the new virus. (Older adults were shown to possess serum neutralizing antibodies to the new virus, most likely due to cross‐immunity with human H1N1 viruses. )

•The combination of A (H1N1) vaccine with trivalent seasonal vaccine would have significant regulatory implications.Therefore, production of a monovalent A (H1N1) vaccine to be used in addition to trivalent seasonal vaccine is the preferred option at this stage.

•moving into production now could result in starting vaccine production with strains of lower growth potential, as was the case for H5N1 A/Vietnam/2004. Manufacturers consistently observed yields less than 50% of those usually obtained with seasonal vaccine viruses.

• Using a poorly growing A (H1N1) virus could reduce global supplies of A (H1N1) vaccine.

The Working Group Declares that:

•It is premature to recommend commercial‐scale production of influenza A (H1N1) vaccine.

Page 47: swine flu , mexican ? 2009 Novel H1N1 pandemic !

The Working Group did make the following recommendations for immediate action:

(i)The WHO Secretariat, should recommend which vaccine viruses should be used for vaccine development as soon as possible

(ii) Essential reagents to calibrate antigenic content should be made available as a priority

(iii) The WHO Secretariat is encouraged to collaborate actively with its Collaborating Centres,Essential Regulatory Laboratories, and with industry, to assess the growth property of vaccine viruses and identify those with best growth potential, in order to maximize output of vaccine.

Page 48: swine flu , mexican ? 2009 Novel H1N1 pandemic !

(iv) Manufacturers are urged to develop clinical trial batches and accelerate initiation of clinical trials of influenza A (H1N1) vaccines and to start preparing for a potential future recommendation to move to commercial‐scale production.

(v) The above activities should not interfere with the present production of the Northern hemisphere seasonal vaccines

(vi) The number of needed doses of A (H1N1) vaccine will depend on the spread of influenza A (H1N1) virus in the next few weeks and on a better definition of the groups to be targeted

(vii) An evidence‐based recommendation for the groups to be targeted for vaccination still requires more data

Page 49: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Influenza is unpredictable. 

Page 50: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Human infection with 2009 H1N1virus: clinical observations from Mexico and

other affected countries, May 2009

Page 51: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Presenting Manifestations:

•Fever: may be absent in one out of six hospitalized patients.•Dehydration•Shortness of breath•Myalgia•Sever malaise•Tachycardia•Tachypnoea•Low O2 sat.•Hypotension•Cyanosis•Acute myocarditis•Cardiopulmonary arrest

*Diarrhoea,nausea,vomiting: uncommon in hospitalized pts (38% of US outpatients) *NO ENCEPHALITIS TO DATE

Page 52: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Hospitalization :

•2-5% of confirmed cases in US and Canada

•6% of confirmed cases in Mexico (in Mexico 33% of hospitalized patients required ventilation as compared to only 13% in California)

•Fatalities are mainly from rapid progression to: ARDS Renal failure Multiorgan failure

•The highest rates of hospitalization are actually in children under 5,  and the next highest rates are in those people 5 to 24.

Preparing ICUs…

Page 53: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Comorbidities associated with complications:

(71% of the hospitalized patients have occurred in people who have an underlying condition )

• Pregnancy:2/5 developed complications: Spontaneous abortion Premature ruptured membrane • Asthma and other lung disease

• Diabetes

• Morbid Obesity

• Autoimmune disorders

• Associated immunosuppressive therapy

• Neurological

• Cardiovascular disease

Page 54: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Lab:

•Leucocytosis/leucopenia

•Lymphopenia

•Elevated aminotransferases

•Elevated LDH was found (retrogradely) in 100% of 16 dead patients

•In some extremely elevated CPK

•1/2 hospitalized pts showed some degree of Renal insufficiency ( 2ry to rhabdomyolysis and myoglobinuria)

•Co-infections with strept. pneumonia and adenovirus have been reported in some Mexican cases.

Page 55: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Pathology (postmortem)

ARDS 2ry to 1ry viral pneumonia including :

• diffuse alveolar damage• Peribronchial and perivascular lymphoctic infiltrates• hyperplastic airway changes• bronchiolitis obliterans

Muscle biopsy: sk ms necrosis

Page 56: swine flu , mexican ? 2009 Novel H1N1 pandemic !

WHO Guidance

Page 57: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Mild Cases:•Supportive: Paracetamol, flds… *NO SALICYLATES IN CHILDREN/ YOUNG ADULTS: REYE'S SYNDROME

•Antivirals : *best within first 48 hours *Early administration in at-risk pts ie those with co-morbidities/pregnancy… *Neuraminidase inhibitors: oral Oseltamivir Inhaled Zanamivir (N H1N1 is resistant to M2 ion channel inhibitors: Amantadine Rimantadine )

•Adequate control precautions: cough etiquette Hand hygiene Natural ventilation

Page 58: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Hospitalized pts:

•Antivirals • Pneumonia management like avian (antibiotics)

• Resp. Support: early detection Correction of hypoxia with supplemental O2 or mech. Vent as necessary

• when mech. vent is indicated: low volume low pressure lung protective vent. Strategy for ARDSSteroids:•Avoid routine use, no benefit was reported . •Higher doses associated with serious SE:

o evidence of increased viral replication in SARS and other resp. viral infections. o Increased mortality in Avian.

Page 59: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Unanswered questions:

Effect of:

• Smoking

• Air pollution

• Faeces and vomitus

Role of flies?

Page 60: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Roooooar!…….

Nobody’s scared of me

nomore!

Roooooar!…….

Nobody’s scared of me

nomore!

Round and round she

goes, where it stops , nobody knows…

Page 61: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Hey, who said

that?

Page 62: swine flu , mexican ? 2009 Novel H1N1 pandemic !

swine flu in humans can vary in severity from mild to severe. Severe disease with pneumonia, respiratory failure and even death

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How Flu Spreads

•Respiratory droplets of coughs and sneezes propelled through the air

and deposited on the mouth or nose or eyes of people nearby.

•when a person touches respiratory droplets on another person or an

object and then touches their own mouth or nose or eyes (or someone

else’s mouth or nose or eyes) before washing their hands.

Page 64: swine flu , mexican ? 2009 Novel H1N1 pandemic !

People with swine flu who are cared for at home should:

I wish everyone

could have a

home like this

Page 65: swine flu , mexican ? 2009 Novel H1N1 pandemic !

• Check with their health care provider about any special care they

might need and about antivirals if they are pregnant or have a health

condition such as diabetes, heart disease, asthma, or emphysema.

• stay home for 7 days after the start of their symptoms or until they

have been symptom-free for 24 hours, whichever is longer

• get plenty of rest

Page 66: swine flu , mexican ? 2009 Novel H1N1 pandemic !

• drink clear fluids (such as water, broth, sports drinks, electrolyte

beverages for infants) to keep from being dehydrated

• cover coughs and sneezes. Clean hands with soap and water or an

alcohol-based hand rub often and especially after using tissues and

after coughing or sneezing into hands.

• avoid close contact with others – do not go to work or school while ill

• be watchful for emergency warning signs that might indicate the need

to seek medical attention

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When to Seek Emergency Medical Care Emergency Warning Signs

Page 68: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Get medical care right away if the sick person at home:

• has difficulty breathing, or chest pain.

• has purple or blue discoloration of the lips.

• is vomiting and unable to keep liquids down .

• has signs of dehydration such as dizziness when standing (hypovolemia),

absence of urination, or in infants, a lack of tears when they cry.

• has seizures (for example, uncontrolled convulsions) .

• is less responsive than normal or becomes confused .

• Irritable child who doesn’t want to be held.

• Flu-like symptoms improve but then return with fever and worse cough.

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Medications to Help Lessen Symptoms of the Flu

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• Fevers and aches can be treated with acetaminophen or ibuprofen, or

other nonsteroidal anti-inflammatory drugs (NSAIDS).

• These medications will not lessen how infectious a person is.

• Check the ingredients on the package label before taking additional

doses.

• Patients with kidney or stomach problems should consult their

health care provider before taking any NSAIDS.

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Warning! Do not give aspirin (acetylsalicylic acid) to children or

teenagers who have the flu; this can cause a rare but serious illness

called Reye’s syndrome.

• Check ingredient labels on over-the-counter cold and flu medications

to see if they contain aspirin.

• The safest care for flu symptoms in children younger than 2 years of

age is using a cool-mist humidifier and a suction bulb to help clear

away mucus.

Page 72: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Steps to Lessen the Spread of Flu in the Home

Page 73: swine flu , mexican ? 2009 Novel H1N1 pandemic !

• Stay informed.

• Follow the cough etiquette:

Cover your nose and mouth with a tissue when you cough or

sneeze.

Throw the tissue in the trash after you use it.

Wash your hands often with soap and water, especially after

you cough or sneeze. Alcohol-based hand cleaners are also

effective.

Avoid touching your eyes, nose or mouth. Germs spread this

way.

Try to avoid close contact with sick people.

Page 74: swine flu , mexican ? 2009 Novel H1N1 pandemic !

• Stay home for 7 days after your symptoms begin or until you have

been symptom-free for 24 hours, whichever is longer.

• Keep away from other household members as much as possible. This

is to keep you from infecting others and spreading the virus further.

• develop a family emergency plan as a precaution.

Page 75: swine flu , mexican ? 2009 Novel H1N1 pandemic !

• limit the spread of germs and prevent infection by teaching and

modelling correct behavior to your children:

to wash hands frequently with soap and water.

Each person should have their own personal towel.

cover coughs and sneezes with tissues.

stay away from others as much as possible if they are sick.

Stay home from work and school if sick.

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Placement of the sick person

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• Keep the sick person in a room separate from the common areas of

the house. For example, a spare bedroom with its own bathroom,to be

cleaned daily with household disinfectant.

• Keep the sickroom door closed.

• Have the sick person wear a surgical mask if they need to be in a

common area of the house near other persons.

Stay away from the

alien virus invasion!

Page 78: swine flu , mexican ? 2009 Novel H1N1 pandemic !

Protect other persons in the home

Page 79: swine flu , mexican ? 2009 Novel H1N1 pandemic !

• The sick person should not have visitors other than caregivers. A

phone call is safer than a visit.

• If possible, have only one adult in the home take care of the sick

person.

• Avoid having pregnant women care for the sick person.

• Maintain good ventilation in shared household areas (e.g., keeping

windows open in restrooms, kitchen, bathroom, etc.).

Page 80: swine flu , mexican ? 2009 Novel H1N1 pandemic !

If you are the caregiver

Page 81: swine flu , mexican ? 2009 Novel H1N1 pandemic !

• Avoid being face-to-face with the sick person.

• When holding small children who are sick, place their chin on your

shoulder so that they will not cough in your face.

I didn’t believe them when they said that smoking was bad for my health… a risk factor for novel H1N1!

Page 82: swine flu , mexican ? 2009 Novel H1N1 pandemic !

• Clean your hands with soap and water or use an alcohol-based hand

rub after you touch the sick person or handle used tissues, or laundry.

• Talk to your health care provider about taking antiviral medication to

prevent the caregiver from getting the flu.

• Monitor yourself and household members for flu symptoms and

contact a telephone hotline or health care provider if symptoms occur.

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• Avoid close contact (less than about 6 feet away) with the sick person

as much as possible.

• If you must have close contact with the sick person (for example, hold

a sick infant), spend the least amount of time possible in close contact

and try to wear a facemask (for example, surgical mask) or N95

disposable respirator(it is harder to breathe through an N95 mask for

long periods of time)

Get in, get out…

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Using Facemasks or Respirators

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• Facemasks and respirators may be purchased at a pharmacy, building

supply or hardware store (not off the street).

• Used facemasks and N95 respirators should be taken off and placed

immediately in the regular trash so they don’t touch anything else.

• Avoid re-using disposable facemasks and N95 respirators if possible.

If a reusable fabric facemask is used, it should be laundered with

normal laundry detergent and tumble-dried in a hot dryer.

• After you take off a facemask or N95 respirator, clean your hands with

soap and water or an alcohol-based hand sanitizer.

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Household Cleaning, Laundry, and Waste Disposal

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• Throw away tissues and other disposable items used by the sick

person in the trash.

• Wash your hands after touching used tissues and similar waste.

• Keep surfaces (especially bedside tables, surfaces in the bathroom,

and toys for children) clean by wiping them down with a household

disinfectant according to directions on the product label.

• Eating utensils should be washed either in a dishwasher or by hand

with water and soap.

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• Linens, eating utensils, and dishes belonging to those who are sick do

not need to be cleaned separately, but importantly these items should

not be shared without washing thoroughly first.

• Wash linens (such as bed sheets and towels) by using household

laundry soap and tumble dry on a hot setting.

• Avoid “hugging” laundry prior to washing it to prevent contaminating

yourself.

• Clean your hands with soap and water or alcohol-based hand rub right

after handling dirty laundry.

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Pandemic Flu Planning Checklist for Individuals and Families

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• To plan for a pandemic:

– Store a two week supply of water and food.

– Periodically check your regular prescription drugs

– Have any nonprescription drugs and other health supplies on hand,

including pain relievers, stomach remedies, cough and cold

medicines, fluids with electrolytes, and vitamins.

– Volunteer with local groups to prepare and assist with emergency

response.

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Ready-to-eat canned meats, fish, fruits, vegetables, beans, and soups

Canned juices Fluids with

electrolytes Bottled water Canned or

jarred baby food and

formula Pet food Protein or fruit

bars Dry cereal or

granola Dried fruit Peanut butter

or nuts Crackers

Cleansing

agent/soap

Soap and water, or

alcohol-based (60-

95%)

hand wash

Flashlight

Batteries

Other non-

perishable items

Portable radio

Manual can opener

Garbage bags 

Tissues, toilet

paper, disposable

diapers

Examples of food and non-perishables Examples of medical, health, and emergency supplies:

Thermometer

Prescribed medical supplies such as glucose and blood-pressure monitoring equipment

Vitamins

Medicines for fever, such as acetaminophen or ibuprofen

Anti-diarrheal medication

Power failure, water shortage….

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Looks to me like he’s conquered his matador , and

has every right to fly……….

Page 93: swine flu , mexican ? 2009 Novel H1N1 pandemic !