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Keynote Address - By Dr. K. Shiva Rama Prasad, Assessment and Utility of Sneha Karma in Disease Management - CME On 19th June 2012, Organized by Department of Panchakarma, At: Seminar Hall,MGAC, DMIMS, Selod (H), Wardha, Maharastra
Citation preview
Assessment and Utility of Sneha
Karma in
Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
19th June 2012At Seminar Hall MGAC Campus
Organized by Department of Panchakarma Mahatma Gandhi Ayurved College DMIMS
Selod (H) Wardha Maharastra
Dr K Shiva Rama Prasad Vice Dean Ayurveda
Prof amp Head of Dept of Panchakrma MGACHampRC Wardha
ldquoldquoDevelop something what Develop something what people want and people want and
NOT What you can doNOT What you can dordquordquo
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Introduction bull Sneha ndash indicates includes
ndash Oiliness Unctuousness Viscidity Lubricity etc
ndash ldquoSnehardquo is the essence of Human ndash ldquoLiferdquo it self is dependent on
ldquoSnehardquondash The entire strength of an individual
is dependent on ldquoSnehardquo
xlEacutearingWucircxEacuteEacuteUEacutearingAringrEacuteCcedil
mEacuteNtildeAcircwEacute mEacuteeumlEacutehEacuteEacute xlEacutearingWucircpEacuteOcircIgraverEacutecedilEacute xlEacutearingWucircxEacuteEacutekrEacuteEacuteparaEacute
pEacuteuEacuteIcircliEacute
ndash xEacuteNtildexEacuteeumlNtildeiEacute
IacutecEacuteIgraveMuumlixEacute
313
Sneha in Normalbull Sneha makes the Vishyanda ie
vilayana ndash which means the dissolution liquefaction destruction death etc ndash The all above are referral to the Dosha
and the Dhatubull The Death is inevitable with the lack of
sneha in the body ndash a cellular death orndash organ function cessation
bull Excess Unctuousness cause thinning of the cell membrane amp intiate the cytokins
bull Apart from it induces the softness and generate Kleda (Glucose ndash as in lipid metabolism)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
xlEacutearingWucirclEacuteCcedil
xlEacutearingWucirc
IgraveuEacutewrEacutelS
qEacuteEacuteSiumluEacuteqEacuteccedil
YsEacutearingSMuumlEacuteUMuumlqEacuteccedil
ndash cEacuteUMuuml
xEacuteOcircsectEacute
2210 ndash IgraveuEacutewrEacuteCcedilSaring
-
IgraveuEacutesEacuterEacutelEacuteqEacuteccedil
Sneha in Normalbull Sneha makes the person with ndash
ndash Increased appetite ndash Clean Kosta (GIT)ndash Increased tissue metabolismndash Control on senses ndash Strength ndash Colour complexion ndash Delayed ageing
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
SIumlmiEacuteEacuteIcircalEacute
zzEacuteNtilderegMuumlEacutearingcedilparaEacute
mEacuteNtildesup1kEacuteiEacuteNtildeIcirceEacuteiumliEacutearingIcirclSigraverEacute IgravelEacuteeEacuteiumlUEacutearing
oEacutesEacuteuEacutehEacuteEacuteiumlžxlEacutearingWucircxxEacutearinguEacuteIuml
pEacuteuEacutearingsup3EacuteU -
zEacuteEacute xEacuteCcedil
E 1 32
What are lipidsbull Sneha vis-agrave-vis Lipids are a broad
group of naturally-occurring molecules which includes -ndash fats waxes sterols fat-soluble
vitamins (such as vitamins A D E and K) monoglycerides diglycerides phospholipids and others
bull The main biological functions of lipids include energy storage as structural components of cell membranes and as ndash
bull important signaling molecules
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
The route of Disease
bull Ayurveda states that ndash disease causative factors are ndash 5 Samprapti Ghataka ndash viz ndash Dosha (Vata Pitta Kapha)ndash Dhatu (Rasa Rakta Mamsa Meda Asthi
Majja Sukra)ndash Agni (Teekshna Manda Vishama)ndash Ama (Leena Aleena)ndash Srotas ndash (13 srotas along with sanjna Chesta
Sthanya amp Artava)bull The manifested Disease is predominantly
in Shakha (peripheral [tissue] ndash not in the Kosta ie Central lumen GIT)
bull As the Disease manifestation starts from Kosta (GIT) and spreads to the (Shakha (Tissues) the pathogen particles are brought back to kosta for elimination of disease
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Bringing the Dosha to Kostabull The methods of Shakha
precipitated Dosha to bring back to Kosta are ndashndash Vruddhi (increasing dosha)ndash Vishyanda (dissolution) ndash is done
by ldquoSnehardquondash Paka (ripening the Dosha)ndash Srotomukha Vishodhana (opening the
srotas outlets)ndash Vata Nigrahana (blocking the neural
reflexes)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
uEacuteeumlNtildeSegravekrEacuteIacutepEacutewrEacutelSlEacuteiEacuteccedil
mEacuteEacuteMuumlEacuteiEacuteccedil
xEacuteeumlEacutearingiEacuteEacutearingqEacuteNtildeZEacuteIgraveuEacutezEacuteEacutearingkEacutelEacuteEacuteiEacuteccedil
zEacuteEacuteZEacuteEacuteCcedil
irEacuteYiuEacuteEacute
qEacutesEacuteEacute MuumlEacutearingcedilCcedil
rEacuteEacuteIcircliEacute
uEacuteEacuterEacuteEacutearingparaEacute
IgravelEacuteaEacuteeumlWucircEacuteiEacuteccedil
-
cEacuteUMuuml
Sneha Vishyandabull The infectious theory is denied in Ayurvedabull The pathogenic origin of Ayurveda is Tridoshabull The levels of Dosha accumulation amp segregation cause the
stages of disease amp pathogenesisbull Reversal of the pathogenesis is based upon the ldquodissolution of
Segregated Doshardquo which is brought back to Central Lumen ndash Kosta and eliminated ndash orndash Suppressive management of Dosha and Disease
bull So the Moorchita Sneha (Taila Ghrita) ndash medicated fragmented lipid bonds join the segregated pathogenic Dosha in Tissues and dissolute liquefy Dosha
bull Lipid fragments leaves the drug active principle in Shakha (where the pathogenesis is) and lodge dissolute Dosha to bring back to Kosta through mucosal secretion
bull From Koshta the sneha lodged Dosha is eliminated
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
ldquoldquoDevelop something what Develop something what people want and people want and
NOT What you can doNOT What you can dordquordquo
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Introduction bull Sneha ndash indicates includes
ndash Oiliness Unctuousness Viscidity Lubricity etc
ndash ldquoSnehardquo is the essence of Human ndash ldquoLiferdquo it self is dependent on
ldquoSnehardquondash The entire strength of an individual
is dependent on ldquoSnehardquo
xlEacutearingWucircxEacuteEacuteUEacutearingAringrEacuteCcedil
mEacuteNtildeAcircwEacute mEacuteeumlEacutehEacuteEacute xlEacutearingWucircpEacuteOcircIgraverEacutecedilEacute xlEacutearingWucircxEacuteEacutekrEacuteEacuteparaEacute
pEacuteuEacuteIcircliEacute
ndash xEacuteNtildexEacuteeumlNtildeiEacute
IacutecEacuteIgraveMuumlixEacute
313
Sneha in Normalbull Sneha makes the Vishyanda ie
vilayana ndash which means the dissolution liquefaction destruction death etc ndash The all above are referral to the Dosha
and the Dhatubull The Death is inevitable with the lack of
sneha in the body ndash a cellular death orndash organ function cessation
bull Excess Unctuousness cause thinning of the cell membrane amp intiate the cytokins
bull Apart from it induces the softness and generate Kleda (Glucose ndash as in lipid metabolism)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
xlEacutearingWucirclEacuteCcedil
xlEacutearingWucirc
IgraveuEacutewrEacutelS
qEacuteEacuteSiumluEacuteqEacuteccedil
YsEacutearingSMuumlEacuteUMuumlqEacuteccedil
ndash cEacuteUMuuml
xEacuteOcircsectEacute
2210 ndash IgraveuEacutewrEacuteCcedilSaring
-
IgraveuEacutesEacuterEacutelEacuteqEacuteccedil
Sneha in Normalbull Sneha makes the person with ndash
ndash Increased appetite ndash Clean Kosta (GIT)ndash Increased tissue metabolismndash Control on senses ndash Strength ndash Colour complexion ndash Delayed ageing
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
SIumlmiEacuteEacuteIcircalEacute
zzEacuteNtilderegMuumlEacutearingcedilparaEacute
mEacuteNtildesup1kEacuteiEacuteNtildeIcirceEacuteiumliEacutearingIcirclSigraverEacute IgravelEacuteeEacuteiumlUEacutearing
oEacutesEacuteuEacutehEacuteEacuteiumlžxlEacutearingWucircxxEacutearinguEacuteIuml
pEacuteuEacutearingsup3EacuteU -
zEacuteEacute xEacuteCcedil
E 1 32
What are lipidsbull Sneha vis-agrave-vis Lipids are a broad
group of naturally-occurring molecules which includes -ndash fats waxes sterols fat-soluble
vitamins (such as vitamins A D E and K) monoglycerides diglycerides phospholipids and others
bull The main biological functions of lipids include energy storage as structural components of cell membranes and as ndash
bull important signaling molecules
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
The route of Disease
bull Ayurveda states that ndash disease causative factors are ndash 5 Samprapti Ghataka ndash viz ndash Dosha (Vata Pitta Kapha)ndash Dhatu (Rasa Rakta Mamsa Meda Asthi
Majja Sukra)ndash Agni (Teekshna Manda Vishama)ndash Ama (Leena Aleena)ndash Srotas ndash (13 srotas along with sanjna Chesta
Sthanya amp Artava)bull The manifested Disease is predominantly
in Shakha (peripheral [tissue] ndash not in the Kosta ie Central lumen GIT)
bull As the Disease manifestation starts from Kosta (GIT) and spreads to the (Shakha (Tissues) the pathogen particles are brought back to kosta for elimination of disease
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Bringing the Dosha to Kostabull The methods of Shakha
precipitated Dosha to bring back to Kosta are ndashndash Vruddhi (increasing dosha)ndash Vishyanda (dissolution) ndash is done
by ldquoSnehardquondash Paka (ripening the Dosha)ndash Srotomukha Vishodhana (opening the
srotas outlets)ndash Vata Nigrahana (blocking the neural
reflexes)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
uEacuteeumlNtildeSegravekrEacuteIacutepEacutewrEacutelSlEacuteiEacuteccedil
mEacuteEacuteMuumlEacuteiEacuteccedil
xEacuteeumlEacutearingiEacuteEacutearingqEacuteNtildeZEacuteIgraveuEacutezEacuteEacutearingkEacutelEacuteEacuteiEacuteccedil
zEacuteEacuteZEacuteEacuteCcedil
irEacuteYiuEacuteEacute
qEacutesEacuteEacute MuumlEacutearingcedilCcedil
rEacuteEacuteIcircliEacute
uEacuteEacuterEacuteEacutearingparaEacute
IgravelEacuteaEacuteeumlWucircEacuteiEacuteccedil
-
cEacuteUMuuml
Sneha Vishyandabull The infectious theory is denied in Ayurvedabull The pathogenic origin of Ayurveda is Tridoshabull The levels of Dosha accumulation amp segregation cause the
stages of disease amp pathogenesisbull Reversal of the pathogenesis is based upon the ldquodissolution of
Segregated Doshardquo which is brought back to Central Lumen ndash Kosta and eliminated ndash orndash Suppressive management of Dosha and Disease
bull So the Moorchita Sneha (Taila Ghrita) ndash medicated fragmented lipid bonds join the segregated pathogenic Dosha in Tissues and dissolute liquefy Dosha
bull Lipid fragments leaves the drug active principle in Shakha (where the pathogenesis is) and lodge dissolute Dosha to bring back to Kosta through mucosal secretion
bull From Koshta the sneha lodged Dosha is eliminated
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Introduction bull Sneha ndash indicates includes
ndash Oiliness Unctuousness Viscidity Lubricity etc
ndash ldquoSnehardquo is the essence of Human ndash ldquoLiferdquo it self is dependent on
ldquoSnehardquondash The entire strength of an individual
is dependent on ldquoSnehardquo
xlEacutearingWucircxEacuteEacuteUEacutearingAringrEacuteCcedil
mEacuteNtildeAcircwEacute mEacuteeumlEacutehEacuteEacute xlEacutearingWucircpEacuteOcircIgraverEacutecedilEacute xlEacutearingWucircxEacuteEacutekrEacuteEacuteparaEacute
pEacuteuEacuteIcircliEacute
ndash xEacuteNtildexEacuteeumlNtildeiEacute
IacutecEacuteIgraveMuumlixEacute
313
Sneha in Normalbull Sneha makes the Vishyanda ie
vilayana ndash which means the dissolution liquefaction destruction death etc ndash The all above are referral to the Dosha
and the Dhatubull The Death is inevitable with the lack of
sneha in the body ndash a cellular death orndash organ function cessation
bull Excess Unctuousness cause thinning of the cell membrane amp intiate the cytokins
bull Apart from it induces the softness and generate Kleda (Glucose ndash as in lipid metabolism)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
xlEacutearingWucirclEacuteCcedil
xlEacutearingWucirc
IgraveuEacutewrEacutelS
qEacuteEacuteSiumluEacuteqEacuteccedil
YsEacutearingSMuumlEacuteUMuumlqEacuteccedil
ndash cEacuteUMuuml
xEacuteOcircsectEacute
2210 ndash IgraveuEacutewrEacuteCcedilSaring
-
IgraveuEacutesEacuterEacutelEacuteqEacuteccedil
Sneha in Normalbull Sneha makes the person with ndash
ndash Increased appetite ndash Clean Kosta (GIT)ndash Increased tissue metabolismndash Control on senses ndash Strength ndash Colour complexion ndash Delayed ageing
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
SIumlmiEacuteEacuteIcircalEacute
zzEacuteNtilderegMuumlEacutearingcedilparaEacute
mEacuteNtildesup1kEacuteiEacuteNtildeIcirceEacuteiumliEacutearingIcirclSigraverEacute IgravelEacuteeEacuteiumlUEacutearing
oEacutesEacuteuEacutehEacuteEacuteiumlžxlEacutearingWucircxxEacutearinguEacuteIuml
pEacuteuEacutearingsup3EacuteU -
zEacuteEacute xEacuteCcedil
E 1 32
What are lipidsbull Sneha vis-agrave-vis Lipids are a broad
group of naturally-occurring molecules which includes -ndash fats waxes sterols fat-soluble
vitamins (such as vitamins A D E and K) monoglycerides diglycerides phospholipids and others
bull The main biological functions of lipids include energy storage as structural components of cell membranes and as ndash
bull important signaling molecules
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
The route of Disease
bull Ayurveda states that ndash disease causative factors are ndash 5 Samprapti Ghataka ndash viz ndash Dosha (Vata Pitta Kapha)ndash Dhatu (Rasa Rakta Mamsa Meda Asthi
Majja Sukra)ndash Agni (Teekshna Manda Vishama)ndash Ama (Leena Aleena)ndash Srotas ndash (13 srotas along with sanjna Chesta
Sthanya amp Artava)bull The manifested Disease is predominantly
in Shakha (peripheral [tissue] ndash not in the Kosta ie Central lumen GIT)
bull As the Disease manifestation starts from Kosta (GIT) and spreads to the (Shakha (Tissues) the pathogen particles are brought back to kosta for elimination of disease
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Bringing the Dosha to Kostabull The methods of Shakha
precipitated Dosha to bring back to Kosta are ndashndash Vruddhi (increasing dosha)ndash Vishyanda (dissolution) ndash is done
by ldquoSnehardquondash Paka (ripening the Dosha)ndash Srotomukha Vishodhana (opening the
srotas outlets)ndash Vata Nigrahana (blocking the neural
reflexes)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
uEacuteeumlNtildeSegravekrEacuteIacutepEacutewrEacutelSlEacuteiEacuteccedil
mEacuteEacuteMuumlEacuteiEacuteccedil
xEacuteeumlEacutearingiEacuteEacutearingqEacuteNtildeZEacuteIgraveuEacutezEacuteEacutearingkEacutelEacuteEacuteiEacuteccedil
zEacuteEacuteZEacuteEacuteCcedil
irEacuteYiuEacuteEacute
qEacutesEacuteEacute MuumlEacutearingcedilCcedil
rEacuteEacuteIcircliEacute
uEacuteEacuterEacuteEacutearingparaEacute
IgravelEacuteaEacuteeumlWucircEacuteiEacuteccedil
-
cEacuteUMuuml
Sneha Vishyandabull The infectious theory is denied in Ayurvedabull The pathogenic origin of Ayurveda is Tridoshabull The levels of Dosha accumulation amp segregation cause the
stages of disease amp pathogenesisbull Reversal of the pathogenesis is based upon the ldquodissolution of
Segregated Doshardquo which is brought back to Central Lumen ndash Kosta and eliminated ndash orndash Suppressive management of Dosha and Disease
bull So the Moorchita Sneha (Taila Ghrita) ndash medicated fragmented lipid bonds join the segregated pathogenic Dosha in Tissues and dissolute liquefy Dosha
bull Lipid fragments leaves the drug active principle in Shakha (where the pathogenesis is) and lodge dissolute Dosha to bring back to Kosta through mucosal secretion
bull From Koshta the sneha lodged Dosha is eliminated
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha in Normalbull Sneha makes the Vishyanda ie
vilayana ndash which means the dissolution liquefaction destruction death etc ndash The all above are referral to the Dosha
and the Dhatubull The Death is inevitable with the lack of
sneha in the body ndash a cellular death orndash organ function cessation
bull Excess Unctuousness cause thinning of the cell membrane amp intiate the cytokins
bull Apart from it induces the softness and generate Kleda (Glucose ndash as in lipid metabolism)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
xlEacutearingWucirclEacuteCcedil
xlEacutearingWucirc
IgraveuEacutewrEacutelS
qEacuteEacuteSiumluEacuteqEacuteccedil
YsEacutearingSMuumlEacuteUMuumlqEacuteccedil
ndash cEacuteUMuuml
xEacuteOcircsectEacute
2210 ndash IgraveuEacutewrEacuteCcedilSaring
-
IgraveuEacutesEacuterEacutelEacuteqEacuteccedil
Sneha in Normalbull Sneha makes the person with ndash
ndash Increased appetite ndash Clean Kosta (GIT)ndash Increased tissue metabolismndash Control on senses ndash Strength ndash Colour complexion ndash Delayed ageing
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
SIumlmiEacuteEacuteIcircalEacute
zzEacuteNtilderegMuumlEacutearingcedilparaEacute
mEacuteNtildesup1kEacuteiEacuteNtildeIcirceEacuteiumliEacutearingIcirclSigraverEacute IgravelEacuteeEacuteiumlUEacutearing
oEacutesEacuteuEacutehEacuteEacuteiumlžxlEacutearingWucircxxEacutearinguEacuteIuml
pEacuteuEacutearingsup3EacuteU -
zEacuteEacute xEacuteCcedil
E 1 32
What are lipidsbull Sneha vis-agrave-vis Lipids are a broad
group of naturally-occurring molecules which includes -ndash fats waxes sterols fat-soluble
vitamins (such as vitamins A D E and K) monoglycerides diglycerides phospholipids and others
bull The main biological functions of lipids include energy storage as structural components of cell membranes and as ndash
bull important signaling molecules
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
The route of Disease
bull Ayurveda states that ndash disease causative factors are ndash 5 Samprapti Ghataka ndash viz ndash Dosha (Vata Pitta Kapha)ndash Dhatu (Rasa Rakta Mamsa Meda Asthi
Majja Sukra)ndash Agni (Teekshna Manda Vishama)ndash Ama (Leena Aleena)ndash Srotas ndash (13 srotas along with sanjna Chesta
Sthanya amp Artava)bull The manifested Disease is predominantly
in Shakha (peripheral [tissue] ndash not in the Kosta ie Central lumen GIT)
bull As the Disease manifestation starts from Kosta (GIT) and spreads to the (Shakha (Tissues) the pathogen particles are brought back to kosta for elimination of disease
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Bringing the Dosha to Kostabull The methods of Shakha
precipitated Dosha to bring back to Kosta are ndashndash Vruddhi (increasing dosha)ndash Vishyanda (dissolution) ndash is done
by ldquoSnehardquondash Paka (ripening the Dosha)ndash Srotomukha Vishodhana (opening the
srotas outlets)ndash Vata Nigrahana (blocking the neural
reflexes)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
uEacuteeumlNtildeSegravekrEacuteIacutepEacutewrEacutelSlEacuteiEacuteccedil
mEacuteEacuteMuumlEacuteiEacuteccedil
xEacuteeumlEacutearingiEacuteEacutearingqEacuteNtildeZEacuteIgraveuEacutezEacuteEacutearingkEacutelEacuteEacuteiEacuteccedil
zEacuteEacuteZEacuteEacuteCcedil
irEacuteYiuEacuteEacute
qEacutesEacuteEacute MuumlEacutearingcedilCcedil
rEacuteEacuteIcircliEacute
uEacuteEacuterEacuteEacutearingparaEacute
IgravelEacuteaEacuteeumlWucircEacuteiEacuteccedil
-
cEacuteUMuuml
Sneha Vishyandabull The infectious theory is denied in Ayurvedabull The pathogenic origin of Ayurveda is Tridoshabull The levels of Dosha accumulation amp segregation cause the
stages of disease amp pathogenesisbull Reversal of the pathogenesis is based upon the ldquodissolution of
Segregated Doshardquo which is brought back to Central Lumen ndash Kosta and eliminated ndash orndash Suppressive management of Dosha and Disease
bull So the Moorchita Sneha (Taila Ghrita) ndash medicated fragmented lipid bonds join the segregated pathogenic Dosha in Tissues and dissolute liquefy Dosha
bull Lipid fragments leaves the drug active principle in Shakha (where the pathogenesis is) and lodge dissolute Dosha to bring back to Kosta through mucosal secretion
bull From Koshta the sneha lodged Dosha is eliminated
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha in Normalbull Sneha makes the person with ndash
ndash Increased appetite ndash Clean Kosta (GIT)ndash Increased tissue metabolismndash Control on senses ndash Strength ndash Colour complexion ndash Delayed ageing
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
SIumlmiEacuteEacuteIcircalEacute
zzEacuteNtilderegMuumlEacutearingcedilparaEacute
mEacuteNtildesup1kEacuteiEacuteNtildeIcirceEacuteiumliEacutearingIcirclSigraverEacute IgravelEacuteeEacuteiumlUEacutearing
oEacutesEacuteuEacutehEacuteEacuteiumlžxlEacutearingWucircxxEacutearinguEacuteIuml
pEacuteuEacutearingsup3EacuteU -
zEacuteEacute xEacuteCcedil
E 1 32
What are lipidsbull Sneha vis-agrave-vis Lipids are a broad
group of naturally-occurring molecules which includes -ndash fats waxes sterols fat-soluble
vitamins (such as vitamins A D E and K) monoglycerides diglycerides phospholipids and others
bull The main biological functions of lipids include energy storage as structural components of cell membranes and as ndash
bull important signaling molecules
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
The route of Disease
bull Ayurveda states that ndash disease causative factors are ndash 5 Samprapti Ghataka ndash viz ndash Dosha (Vata Pitta Kapha)ndash Dhatu (Rasa Rakta Mamsa Meda Asthi
Majja Sukra)ndash Agni (Teekshna Manda Vishama)ndash Ama (Leena Aleena)ndash Srotas ndash (13 srotas along with sanjna Chesta
Sthanya amp Artava)bull The manifested Disease is predominantly
in Shakha (peripheral [tissue] ndash not in the Kosta ie Central lumen GIT)
bull As the Disease manifestation starts from Kosta (GIT) and spreads to the (Shakha (Tissues) the pathogen particles are brought back to kosta for elimination of disease
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Bringing the Dosha to Kostabull The methods of Shakha
precipitated Dosha to bring back to Kosta are ndashndash Vruddhi (increasing dosha)ndash Vishyanda (dissolution) ndash is done
by ldquoSnehardquondash Paka (ripening the Dosha)ndash Srotomukha Vishodhana (opening the
srotas outlets)ndash Vata Nigrahana (blocking the neural
reflexes)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
uEacuteeumlNtildeSegravekrEacuteIacutepEacutewrEacutelSlEacuteiEacuteccedil
mEacuteEacuteMuumlEacuteiEacuteccedil
xEacuteeumlEacutearingiEacuteEacutearingqEacuteNtildeZEacuteIgraveuEacutezEacuteEacutearingkEacutelEacuteEacuteiEacuteccedil
zEacuteEacuteZEacuteEacuteCcedil
irEacuteYiuEacuteEacute
qEacutesEacuteEacute MuumlEacutearingcedilCcedil
rEacuteEacuteIcircliEacute
uEacuteEacuterEacuteEacutearingparaEacute
IgravelEacuteaEacuteeumlWucircEacuteiEacuteccedil
-
cEacuteUMuuml
Sneha Vishyandabull The infectious theory is denied in Ayurvedabull The pathogenic origin of Ayurveda is Tridoshabull The levels of Dosha accumulation amp segregation cause the
stages of disease amp pathogenesisbull Reversal of the pathogenesis is based upon the ldquodissolution of
Segregated Doshardquo which is brought back to Central Lumen ndash Kosta and eliminated ndash orndash Suppressive management of Dosha and Disease
bull So the Moorchita Sneha (Taila Ghrita) ndash medicated fragmented lipid bonds join the segregated pathogenic Dosha in Tissues and dissolute liquefy Dosha
bull Lipid fragments leaves the drug active principle in Shakha (where the pathogenesis is) and lodge dissolute Dosha to bring back to Kosta through mucosal secretion
bull From Koshta the sneha lodged Dosha is eliminated
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
What are lipidsbull Sneha vis-agrave-vis Lipids are a broad
group of naturally-occurring molecules which includes -ndash fats waxes sterols fat-soluble
vitamins (such as vitamins A D E and K) monoglycerides diglycerides phospholipids and others
bull The main biological functions of lipids include energy storage as structural components of cell membranes and as ndash
bull important signaling molecules
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
The route of Disease
bull Ayurveda states that ndash disease causative factors are ndash 5 Samprapti Ghataka ndash viz ndash Dosha (Vata Pitta Kapha)ndash Dhatu (Rasa Rakta Mamsa Meda Asthi
Majja Sukra)ndash Agni (Teekshna Manda Vishama)ndash Ama (Leena Aleena)ndash Srotas ndash (13 srotas along with sanjna Chesta
Sthanya amp Artava)bull The manifested Disease is predominantly
in Shakha (peripheral [tissue] ndash not in the Kosta ie Central lumen GIT)
bull As the Disease manifestation starts from Kosta (GIT) and spreads to the (Shakha (Tissues) the pathogen particles are brought back to kosta for elimination of disease
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Bringing the Dosha to Kostabull The methods of Shakha
precipitated Dosha to bring back to Kosta are ndashndash Vruddhi (increasing dosha)ndash Vishyanda (dissolution) ndash is done
by ldquoSnehardquondash Paka (ripening the Dosha)ndash Srotomukha Vishodhana (opening the
srotas outlets)ndash Vata Nigrahana (blocking the neural
reflexes)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
uEacuteeumlNtildeSegravekrEacuteIacutepEacutewrEacutelSlEacuteiEacuteccedil
mEacuteEacuteMuumlEacuteiEacuteccedil
xEacuteeumlEacutearingiEacuteEacutearingqEacuteNtildeZEacuteIgraveuEacutezEacuteEacutearingkEacutelEacuteEacuteiEacuteccedil
zEacuteEacuteZEacuteEacuteCcedil
irEacuteYiuEacuteEacute
qEacutesEacuteEacute MuumlEacutearingcedilCcedil
rEacuteEacuteIcircliEacute
uEacuteEacuterEacuteEacutearingparaEacute
IgravelEacuteaEacuteeumlWucircEacuteiEacuteccedil
-
cEacuteUMuuml
Sneha Vishyandabull The infectious theory is denied in Ayurvedabull The pathogenic origin of Ayurveda is Tridoshabull The levels of Dosha accumulation amp segregation cause the
stages of disease amp pathogenesisbull Reversal of the pathogenesis is based upon the ldquodissolution of
Segregated Doshardquo which is brought back to Central Lumen ndash Kosta and eliminated ndash orndash Suppressive management of Dosha and Disease
bull So the Moorchita Sneha (Taila Ghrita) ndash medicated fragmented lipid bonds join the segregated pathogenic Dosha in Tissues and dissolute liquefy Dosha
bull Lipid fragments leaves the drug active principle in Shakha (where the pathogenesis is) and lodge dissolute Dosha to bring back to Kosta through mucosal secretion
bull From Koshta the sneha lodged Dosha is eliminated
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
The route of Disease
bull Ayurveda states that ndash disease causative factors are ndash 5 Samprapti Ghataka ndash viz ndash Dosha (Vata Pitta Kapha)ndash Dhatu (Rasa Rakta Mamsa Meda Asthi
Majja Sukra)ndash Agni (Teekshna Manda Vishama)ndash Ama (Leena Aleena)ndash Srotas ndash (13 srotas along with sanjna Chesta
Sthanya amp Artava)bull The manifested Disease is predominantly
in Shakha (peripheral [tissue] ndash not in the Kosta ie Central lumen GIT)
bull As the Disease manifestation starts from Kosta (GIT) and spreads to the (Shakha (Tissues) the pathogen particles are brought back to kosta for elimination of disease
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Bringing the Dosha to Kostabull The methods of Shakha
precipitated Dosha to bring back to Kosta are ndashndash Vruddhi (increasing dosha)ndash Vishyanda (dissolution) ndash is done
by ldquoSnehardquondash Paka (ripening the Dosha)ndash Srotomukha Vishodhana (opening the
srotas outlets)ndash Vata Nigrahana (blocking the neural
reflexes)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
uEacuteeumlNtildeSegravekrEacuteIacutepEacutewrEacutelSlEacuteiEacuteccedil
mEacuteEacuteMuumlEacuteiEacuteccedil
xEacuteeumlEacutearingiEacuteEacutearingqEacuteNtildeZEacuteIgraveuEacutezEacuteEacutearingkEacutelEacuteEacuteiEacuteccedil
zEacuteEacuteZEacuteEacuteCcedil
irEacuteYiuEacuteEacute
qEacutesEacuteEacute MuumlEacutearingcedilCcedil
rEacuteEacuteIcircliEacute
uEacuteEacuterEacuteEacutearingparaEacute
IgravelEacuteaEacuteeumlWucircEacuteiEacuteccedil
-
cEacuteUMuuml
Sneha Vishyandabull The infectious theory is denied in Ayurvedabull The pathogenic origin of Ayurveda is Tridoshabull The levels of Dosha accumulation amp segregation cause the
stages of disease amp pathogenesisbull Reversal of the pathogenesis is based upon the ldquodissolution of
Segregated Doshardquo which is brought back to Central Lumen ndash Kosta and eliminated ndash orndash Suppressive management of Dosha and Disease
bull So the Moorchita Sneha (Taila Ghrita) ndash medicated fragmented lipid bonds join the segregated pathogenic Dosha in Tissues and dissolute liquefy Dosha
bull Lipid fragments leaves the drug active principle in Shakha (where the pathogenesis is) and lodge dissolute Dosha to bring back to Kosta through mucosal secretion
bull From Koshta the sneha lodged Dosha is eliminated
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Bringing the Dosha to Kostabull The methods of Shakha
precipitated Dosha to bring back to Kosta are ndashndash Vruddhi (increasing dosha)ndash Vishyanda (dissolution) ndash is done
by ldquoSnehardquondash Paka (ripening the Dosha)ndash Srotomukha Vishodhana (opening the
srotas outlets)ndash Vata Nigrahana (blocking the neural
reflexes)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
uEacuteeumlNtildeSegravekrEacuteIacutepEacutewrEacutelSlEacuteiEacuteccedil
mEacuteEacuteMuumlEacuteiEacuteccedil
xEacuteeumlEacutearingiEacuteEacutearingqEacuteNtildeZEacuteIgraveuEacutezEacuteEacutearingkEacutelEacuteEacuteiEacuteccedil
zEacuteEacuteZEacuteEacuteCcedil
irEacuteYiuEacuteEacute
qEacutesEacuteEacute MuumlEacutearingcedilCcedil
rEacuteEacuteIcircliEacute
uEacuteEacuterEacuteEacutearingparaEacute
IgravelEacuteaEacuteeumlWucircEacuteiEacuteccedil
-
cEacuteUMuuml
Sneha Vishyandabull The infectious theory is denied in Ayurvedabull The pathogenic origin of Ayurveda is Tridoshabull The levels of Dosha accumulation amp segregation cause the
stages of disease amp pathogenesisbull Reversal of the pathogenesis is based upon the ldquodissolution of
Segregated Doshardquo which is brought back to Central Lumen ndash Kosta and eliminated ndash orndash Suppressive management of Dosha and Disease
bull So the Moorchita Sneha (Taila Ghrita) ndash medicated fragmented lipid bonds join the segregated pathogenic Dosha in Tissues and dissolute liquefy Dosha
bull Lipid fragments leaves the drug active principle in Shakha (where the pathogenesis is) and lodge dissolute Dosha to bring back to Kosta through mucosal secretion
bull From Koshta the sneha lodged Dosha is eliminated
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha Vishyandabull The infectious theory is denied in Ayurvedabull The pathogenic origin of Ayurveda is Tridoshabull The levels of Dosha accumulation amp segregation cause the
stages of disease amp pathogenesisbull Reversal of the pathogenesis is based upon the ldquodissolution of
Segregated Doshardquo which is brought back to Central Lumen ndash Kosta and eliminated ndash orndash Suppressive management of Dosha and Disease
bull So the Moorchita Sneha (Taila Ghrita) ndash medicated fragmented lipid bonds join the segregated pathogenic Dosha in Tissues and dissolute liquefy Dosha
bull Lipid fragments leaves the drug active principle in Shakha (where the pathogenesis is) and lodge dissolute Dosha to bring back to Kosta through mucosal secretion
bull From Koshta the sneha lodged Dosha is eliminated
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha timingbull The consumption of sneha as
ndash shodhana is in the morning when the previous day meal is digested
ndash for shamana it is consumed in the nightbull Day snehana in cold season Vata
sleshma predominance amp bull Night snehana in hot season
Vatapitta predominance
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Charaka sutra 1361 Susruta chikitsa 31 23-24 Sharngdhara Uttara 115
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sneha Typology bull The lipids vivid in use are ndash Taila Ghrita Vasa and Majja (these sneha are used
either one or in combination amp permutations according to the severity and Dosha predominance)
bull Abhyantara (Internal)ndash Pana (oral administration ndash Shodhananga ndash to eliminate the Dosha)ndash Bhojana (oral ndash Shamananga ndash to pacify the Dosha)
bull Bahya (External)ndash Anuvasana (per-rectal) Uttara (per-urethral) Nasya (per-
nasal) Karna Poorana (per-ear canal) Gandusha (per-oral gargling) Akshi Tarpana (per-ophthalmic)
ndash Moordhnitaila Chikitsa (Shirovasti [Residual oil] Pichu [oil patch] dhara [oil pouring] mastishkya [oil cover] lepa [oily paste])
ndash Gatrabhyanga (body massage) Padabhyanaga (pedal massage) Mardana (centrifugal massage) Udwartana (centripetal massage) Padaghata (Foot Massage) Samhanana (smooth massage)
ndash Parisheka (pouring) Avagaha (submerging)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Dalhana Clarificationbull Ayurveda suggest the
Snana (bath) before external oil application ndash Abhyanaga (Massage)ndash It facilitates the rapid
absorption of the Sneha used and reaches the target faster
bull In the context of Abhyanaga Dalhana (SuChi 2430) has clarified about the dynamics of Sneha absorption from the skin -
bull Sneha reaches ndashbull Romakoopa (hair follicle) in
300 matra (95sec)bull Twak (Skin) in 400 matra (133
sec)bull Rakta (Blood) in 500 matra
(160 sec)bull Mamsa (muscle) in 600 matra
(190sec)bull Medas (Fat) in 700 sec (228
sec)bull Asthi (bone) in 800 matra (245
sec)bull Majja (Marrow) in 900 matra
(285sec)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Sadyah-Snehabull Sadyah-Sneha means instant unctuousness bull Sandhava Lavana added sneha (Ghee Oil) is a
faster unctuous agent as it has the qualities of ndashndash Abhshyandi ndash quality of liquefactionndash Arooksha ndash non dry ndash Sookshma ndash minutendash Ushna ndash hot ndash Vyavayi ndash spreads in the body well before to digest
bull These qualities enhance the unctuousness in the body instantly
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
sEacuteuEacutehEacuteEacutearingmEacuteIgraveWucirciEacuteEacute xlEacutearingWucircEacute xlEacutearingWucircrEacutelirEacuteIacutecEacuteUEacutesup3EacuteUqEacuteccedil
-
cEacutexEacuteeumlMuuml
xEacuteOcircsectEacute
1398
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Best Sneha for Practice bull Out of the 4 sneha we
practice the best two are ndashndash Morchita tilataila(Sha Sam Madyama 613-14)ndash Kolakulutha Ghrita(cha Su 1394)
bull Apart from the sadya sneha of ndashndash Dharoshna Sneha(Sha Sam Uttara 120)
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Disease management with Snehabull Even though the Shodhananga Sneha
pana is practiced in Vata vyadhi amp twak (Skin) diseases ndash many other areas are also indicated ndash vizndash Jwara Gulma Rajayakshma Apasmara
Unmada Shotha Udara Kasa swasa Grahani Pandu Shiroroga Yonivyapat Vandhya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Utility of Snehabull Sneha is used as Vicharana or directly as Sneha pana
either to pacify (Shamana) the disease or to expel (Shodhana)
bull The regulated use of the sneha will make the person to expel the deposited sneha (fats) and restructure the ldquofatty contentsrdquo in the body
bull The excess usage of Sneha cause the ldquoSantarpanotha Vikarardquo (Over Nutritive Disorders) such as Medomaya Yakrut Ama Kusta pandu Jwara Sthoulya Vandhya Klaibya etc
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment of snehabull Assessment of the Samyak Snehana is done by the Symptomsbull Here we observe the 3 sets as ndash Jeeryamana Jeerna amp Samyak
lakshana (symptoms)bull Why not a parametric evaluation is introduced to check the same
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
bullJeeryamana lakshana
bullsamyak lakshana
bullJeerna lakshana
AHSu 1630SuChi 31 43ChaSu1338AH Su 25 Su chi 31 33
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
ASAMYAK SNIGDHA LAKSHANAS
bull Asnigdha Lakshanas ndash Ruksha Purisha Grathita Purisha Apravaguna Vata Mrdu Pakta Kharatva Raukshyata
bull Ati Snigdha Lakshana ndash Panduta Gaurava Jadya Tandra Aruchi Utklesha Purishasya Avipakvata
bull SNEHAPANA VYAPAT - Tandra Utklesha Anaha Jvara Stambha Visanmyatha Kushta Pandu Kandu Shopha Arsha Aruchi Trishna GrahaniDosha Staimitya Vakyanigraha Shula Ama Pradosha
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Objective parameter for Sneha Assessment
bull As the observation offer an area of setting the objective assessment apart from ldquoLipid Profilerdquo
bull The sneha (Fat) quantity in the fecal matter is the best method as ndashndash The samyak sneha symptom is oiliness in
fecal matter - andndash the excess is also seen in the same
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO
HYPERLIPIDAEMIA AND NORMALLIPID VALUES
bull Large quantities of Sneha is using for Snehapana the people in this era are afraid of this therapy because it may increase fat specially Cholesterol and Triglycerides which was the important causative factor for Atherosclerosis Heart attack etc
bull Shodhananga Snehapana with Murchita Tila Taila was given in Arohana Krama in two groups
bull In one group the 15 patients with primary Hyperlipidaemia (especially raised values of either Cholesterol or Triglycerides) and who are fit for Snehana and Shodhana karma excluding secondary Hyperlipidaemia were selected
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
STUDY OF AROHANA SNEHAPANA continued
bull In both the groups after Ama Pachana Snehapana was done in Arohana krama after 30ml of Hrasiyasi matra ndash the result is under -
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Varsha S Kulkarni THE STUDY OF AROHANA SNEHAPANA AND ITS EFFECT ON SAMEDARAKTA WITH SPECIAL REFERENCE TO HYPERLIPIDAEMIA AND NORMAL LIPID VALUES 2005 RGUHS Bangalore
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation
bull In the present study investigated the effect of 10 dietary ghee on microsomal lipid peroxidation as well as serum lipid levels in Fischer inbred rats to assess the effect of ghee on free radical mediated processes that are implicated in many chronic diseases including cardiovascular disease
bull Results showed that 10 dietary ghee fed for 4 weeks did not have any significant effect on levels of serum total cholesterol but did increase triglyceride levels in Fischer inbred rats
bull Ghee at a level of 10 in the diet did not increase liver microsomal lipid peroxidation or liver microsomal lipid peroxide levels
bull Animal studies have demonstrated many beneficial effects of ghee including dose-dependent decreases in serum total cholesterol low density lipoprotein (LDL) very low density lipoprotein (VLDL) and triglycerides decreased liver total cholesterol triglycerides and cholesterol esters and a lower level of nonenzymatic-induced lipid peroxidation in liver homogenate
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hari Sharma etal Ayu 2010 Apr-Jun 31(2) 134ndash140
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Influence of vitamin D supplementation on plasma lipid profiles A meta-analysis ofrandomized controlled trials
bull Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile However the intervention studies gave divergent results
bull The mean change in total cholesterol (TC) low-density lipoprotein cholesterol (LDL-C) high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) from baseline was treated as a continuous variable
bull In all 12 clinical trials consisting of 1346 participants were included in the analysis
bull The pooled estimate of effect for vitamin D supplementation on LDL-C was 323 mgdl (95 confidence interval 055 to 590 mgdl)
bull No statistically significant effects for vitamin D supplementation were observed for TC HDL-C and TG (differences in means were 152 mgdl (-142 to 446 mgdl) -014 mgdl (-099 to 071 mgdl) and -192 mgdl (-772 to 388 mgdl) respectively)
bull The lipid modulating effects of vitamin D supplementation should be further investigated though large-scale randomized trials with adequate doses which can effectively elevated the active form of vitamin D in plasma and with proper population which has hyper-lipemia as an inclusion criterion
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Wang et al Lipids in Health and Disease 2012 1142 1142 httpwwwlipidworldcomcontent11142
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in
patients with rheumatoid arthritis
bull Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids
bull A correlation with clinical and laboratory parameters is also reported No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids
bull Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
M MAGARO et al Annals of the Rheumatic Diseases 1988 47 793-796
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the
secretion of biliary lipidsbull To evaluate the mechanism of the hypocholesterolemic effect of ghee
male Wistar rats were fed a diet containing 25 or 50 wt ghee for a period of 8 weeks The diets were made isocaloric with groundnut oil
bull Both native and ghee heated at 120 degrees C containing oxidized lipids were included in the diet The ghee in the diet did not affect the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in the liver microsomes but it significantly increased biliary excretion of cholesterol bile acids uronic acid and phospholipids
bull The rats fed ghee had lower levels of cholesterol esters in the serum as well as in the intestinal mucosa Both native and oxidized ghee influenced cholesterol metabolism
bull These results indicate that supplementation of diets with ghee lipids would increase the excretion of bile constituents and lower serum cholesterol levels
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Kumar MV Sambaiah K Lokesh BR J Nutr Biochem 2000 Feb11(2)69-75
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
Conclusion
bull The Sneha bound medicines are long acting with smaller chains of Lipid molecules
bull The Ayurvedic Medicinal Fats are homogeneous and target oriented
bull The sneha in Ayurveda (under normal dose) does not increase the fats in body rather regulate them
bull Assessment parametric in Ayurveda is based upon the ldquoSymptomsrdquo is necessary to be shifted for Objective Type
bull Even though the Fatty Medicine usage in Ayurveda is more ndash a standard research to establish the facts is necessary
Assessment and Utility of Sneha Karma in Disease Management
Dr K Shiva Rama
Prasad at httpwwwtechnoayurvedacom
