plegable biologia Molecular - Sarah Restrepo

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Maria Sarah Restrepo

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INTRODUCTION

A REVOLUTIONARY SYSTEM FOR PROTEIN ANALYSIS, THAT HELPS IN A BETTER WAY, TO UNDERSTAND THE NATURE OF PROTEINS IN DISEASES.

NEW METHOD FOR THE STUDIED OF VIRAL VECTORS THAT HAS BEEN DEVELOPED, TO SIMPLIFY EVERY STEP OF THE PROCEDURE.

PROTEINSIMPLE REINVENTS THE WESTERN BLOTMarketwatch. August 30-2011

PROTEINSIMPLE REINVENTS THE WESTERN BLOT

ProteinSimple today introduced a revolutionary new system for protein analysis, Simon and the Simple Western. The Simple Western is a complete reinvention of the Western Blot, and is truly a historic breakthrough for protein research.

For the first time in 30 years, researchers have access to a completely automated, walk-away solution for Western analysis.


The Western Blot was invented in 1979 and to this day remains the most frequently used technique for protein characterization.

Traditional Westerns require many manual steps using gels, transfer tanks, blots and film, and a single experiment can take up to 24 hours to complete.


The Simple Western is a Western with none of the hassle. No messy gels, no transfer tanks, no blots, no imaging and no manual analysis.

Simply load your samples into Simon, push a button, walk away and come back a few hours later to fully analyzed data.


OBSERVATIONS

This revolutionary discovery only proves the magnificent importance of technology in Medicine Procedures. With the Simple Western, researchers not only economice time and Money, but gain a faster and developed way to investigate the Proteins and their influence in some diseases.

FASTER, SCALABLE METHOD FOR PRODUCING AAV-BASED GENE TRANSFER VECTORSScience Daily. January 05-2011

FASTER, SCALABLE METHOD FOR PRODUCING AAV-BASED GENE TRANSFER VECTORS

A new, simplified method for producing large amounts of viral vector cassettes capable of shuttling genes into host cells will help advance the promising field of gene therapy as applications move into large animal studies and human clinical trials.


This new method for creating stable AAV2 producer cell lines overcomes the major drawbacks of the previous method: it requires only a one-step cloning process (instead of multiple cloning steps).


In addition to being faster and easier, their simplified method offers other important advantages, including the potential to produce high yields of multiple AAV serotypes upon co-infection with a helper adenovirus.


AAV gene therapy is showing promise in the clinic.

Important challenges exist for it to become a commercial product such as scalable manufacturing processes.

OBSERVATIONS

A versatil method like this new one, can be an ex- traodinary and useful tool for the scientific community, reducing the steps of de older method and be- coming a way to develop the AAV genes therapies, that today have the potential to be a commercial product.


With the simply Western, is easier to understand the behavior of proteins and everything that tours around them.


With the new Method for the stu- dy of AAV gene vector, the scientific community is able to put on the medical market a very important treatment as the AAV gene thera-py with more certain results.


BIBLIOGRAPHY

ProteinSimple Reinvents the Western Blot. Marketwatch [online]. [ref. Agost 30, 2011]. Available online http://www.marketwatch.com/story/protei nsimple-reinvents-the-western-blot-2011- 08-30

Faster, Scalable Method for Producing AAV-Based Gene Transfer Vectors. Science Daily [online]. [ref. January 5, 2011]. Avai- lable online <http://www.sciencedaily.com/releases/2

THANKS

Health & Medicine

plegable biologia Molecular - Sarah Restrepo