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Over-the-Counter Medications
The Market
Therapeutic Classes
Commercial Products
The OTC Market Place
Market Design Self-Care Movement Self Medication
Risks Benefits
Prevalence of OTC use
Law Review
Impact
OTC Industry Trends
Sales USA Global
Product Categories Active ingredients Product selection
Rx-OTC Switch Movement
Patient counseling Real medicines
OTC Labeling
Drug ClassificationStudy Chart Example
Classification
Purpose &
Therapeutic Effect
Adverse
Effects
Cautions &
Warnings
Patient
Education
Analgesia
Pain Organic Psychogenic
Anatomy of Pain SensationTypes of Pain Headache, migraine Osteoarthritis, RA Neuralgia, myalgia,
arthralgia, bursitis Menstrual (diuretics)
Oral Analgesics (Internal)
Active Ingredients Salicylates (ASA-acetyl salicylic acid) Para-aminophenol (APAP-acetaminophen) Non-steroidal anti-inflammatory (NSAIDS)
(IBU-ibuprofen)
Mechanism of Action (MOA)
Side Effects (SE)
Topical Analgesics (External)
Capsaicin (Zostrix)
Salicylates (Aspercreme)
Menthol (Mineral Ice, Flexall, Jointritis)
Camphor (Bayer Muscle & Joint)
Thermacare
Is it a Cold or the Flu?Cold Flu
Fever –rareHA –rareAches/pains- slightFatigue/weak-mildRunny/stuffy nose-commonSneeze- usualSore throat- commonChest discomfort-mild
High 102-104FProminentUsual & severeExtreme – 2-3 weeksSometimes
SometimesSometimesCommon
Anti-diarrheals
Diarrhea Types Self-limiting
OTC Treatments Non-drug
BRAT Drug
Adsorbents Kaolin,pectin, bismuth
GIT sedatives loperamide
Laxatives
Constipation
Treatment Bulk forming Emollient Lubricants Saline Stimulant Stool softener
Anti-Emetics
Physiology Vomiting center Chemoreceptor trigger zone
Treatment Meclizine, cyclizine Dimenhydrinate Fructose/sucrose
Coke syrup Emetrol
Sea Bands
Antacids
Neutralizers Ingredients Na++ Bicarbonate Ca++ Carbonate Aluminum Hydroxide Magnesium Hydroxide Alginic Acid
Anti-flatulence Simethicone
Digestive Enzymes
Acid Reducers
Physiology
Ingredients Histamine-2 (H-2) Receptor Blockers
Cimetidine Famotidine Ranitidine
Proton Pump Inhibitors (PPI) Omeprazole
The Common Cold
Rhinovirus LRI URI
Rhinitis Allergic
Seasonal Perennial
Infectious Non allergic
Nasal DecongestantsTopical Oral
MOA
Agents Ephedrine Phenylephrine Naphazoline Oxymetazoline Xylometazoine
SE
MOA
Agents Ephedrine Phenylephrine Pseudo ephedrine
SE
The Sinus Headache
Anti-Tussives
Types of Cough Congested, productive Congested, non-
productive Dry, non-productive
Agents Expectorants
Guaifenesin
Central Acting Suppressants
Dextromethorphan
Intermission