ELECTROPHYSIOLOGY – Portfolio Product Management, Michael Braun September 2014

OSYPKA EP-Portfolio DIAGNOSTIC CATHETER: Non-Steerabale Diagnostic Catheter • OSYPKA „FINDER pure“ • OSYPKA „FINDER“

Steerabale Diagnostic Catheter • OSYPKA „SIRIUS (45mm)“ • OSYPKA „SIRIUS (60mm)“ • OSYPKA „SIRIUS flutter“

OUTSTANDING OUTSTANDING

OSYPKA EP-Portfolio ABLATION CATHETER: Non-irrigated Ablation Catheter • OSYPKA „CERABLATE easy“ • OSYPKA „CERABLATE flutter“

Irrigated Ablation Catheter • OSYPKA „CERABLATE cool“

OSYPKA EP-Portfolio ACCESSORIES: Steerable Sheath • OSYPKA „DESTINO“

Standard positions for diagnostic catheter during EP-examination

5

HRA

HIS

RVA

CS

OSYPKA „FINDER®“

OSYPKA „FINDER®“

FINDER is our high quality multipolar diagnostic catheter for intra cardiac sensing and pacing for electrophysiology procedures. The FINDER catheters flexible designs and ability to retain their shapes meet the requirements of practical application: Exceptional longitudinal stability and torque ability enable fast and precise positioning.

OSYPKA „FINDER®“ Key features: • Excellent tissue contact due to bulky electrodes • Braided tubing of catheter ensures excellent torqueability • Atraumatic flexible catheter tip • Optimal curve stability • Continuous flexibility of catheter with decreasing rigidity

toward distal tip • Diameter 5F or 6F • 4-, 6- and 10-polar • Spacing 2 mm, 5 mm or 2-5-2 mm • Length 110 cm

OSYPKA „FINDER pure®“

OSYPKA „FINDER pure®“ The FINDER pure diagnostic catheter allow fast, stable and constant positioning and good tissue contact, excellent torque ability and longitudinal stability. The design characteristics ensure optimum long-term stability of the catheter at body temperature, while the precious metal electrodes deliver superior sensing capabilities and thus an outstanding signal quality. Our FINDER pure is an economic model for diagnostic therapy procedures in electrophysiology.

OSYPKA „FINDER pure®“ Key features: • Good tissue contact due to flat electrodes • Optimal curve stability • Diameter 6F • 4-, and 10-polar • Spacing 2 mm, 5 mm or 2-5-2 mm • Length 110 cm • Available in several curve shapes (J-, C-, D-curve, HIS-Hugger

curve)

Product differences between FINDER and FINDER pure

Curve recomandations

OSYPKA FINDER/FINDER pure for …

Atrium • FAT(r/l)/EAT • Atrial Flutter • AVNRT • AFIB

Ventricle • RVOT/LVOT • VT

Atrium and Ventricle

• WPW • AVRT

OSYPKA „SIRIUS®“

OSYPKA „SIRIUS®“

The new OSYPKA SIRIUS is a steerable mapping catheter for electrophysiological intracardial diagnostic procedures, especially coronary sinus mapping. The SIRIUS catheter shaft together with the new handle design allow optimal placement and stable tissue wall contact due to an ideal balance between torque control, flexibility, and smooth deflection of the tip curvature.

OSYPKA „SIRIUS®“ Key features:

• Force for manipulating the catheter tip can be adjusted individually

• Improved torque control and curve stability • Optimized curve shape for placement in the coronary sinus • Good x-ray visibility and signal quality • Diameter 6F • 4- or 10-polar • Spacing 5 mm, 2-5-2 mm (and 2-8-2 mm) • Curve diameter 45 mm (and 60 mm) • Length 110 cm

OSYPKA „SIRIUS®“ Optimized curve shape for placement in the coronary sinus

new SIRIUS curve

old SIRIUS curve

OSYPKA SIRIUS® for …

Atrium • FAT(r/l)/EAT • Atrial Flutter • AVNRT • AFIB

Ventricle • RVOT/LVOT • VT

Atrium and Ventricle

• WPW • AVRT

OSYPKA „CERABLATE easy®“

OSYPKA „CERABLATE easy®“ The Cerablate easy is a steerable ablation catheter for radio frequency ablation of cardiac arrhythmias, such as: • AVNRT (AV-Node Re-entry Tachycardias) • WPW (Wolff-Parkinson-White) Syndrome • RVOT (Right Ventricular Outflow Tract) Tachycardias The Cerablate easy catheter shaft together with the new handle design allow optimal placement and stable tissue wall contact due to an ideal balance between torque control, flexibility, and smooth deflection of the tip curvature.

OSYPKA „CERABLATE easy®“ Key features:

• Force for manipulating the catheter tip can be adjusted individually

• Superior handling characteristics • Precise, smooth movement of the curve setting • Outstanding torque control • Optimal curve stability • Very good x-ray visibility • Excellent temperature response • Compatible with all commonly available radio frequency

generators for cardiac arrhythmia ablation

OSYPKA CERABLATE easy® for …

Atrium • FAT(r/l)/EAT • Atrial Flutter • AVNRT • AFIB

Ventricle • RVOT/LVOT • VT

Atrium and Ventricle

• WPW • AVRT

OSYPKA „CERABLATE flutter®“

OSYPKA „CERABLATE flutter®“ The CERABLATE flutter® is a newly designed radiofrequency-powered ablation catheter with an 8 mm gold tip for the treatment of atrial flutter. The catheter features a special tip design where the second electrode is very close to the tip electrode, which is ideally suited for high-voltage mapping, an advanced technique in the treatment of atrial flutter. This unique design in combination with the gold tip aims to reduce thrombus formation, thus increasing patient safety and procedure efficacy for the treatment of these types of cardiac arrhythmias.

OSYPKA „CERABLATE flutter®“ Key features:

• Full circle 270°deflection offers excellent tissue contact • Spacing: really short spacing between the first and second

electrode for better signal quality • Specialized shaft construction for better steering control • Length 110cm • Diameter 7F • Curve diameter 30, 45 or 60 mm • TIP Size: 8mm (gold)

OSYPKA „CERABLATE flutter®“ Key features:

• Precise, smooth movement of the curve setting • Very good x-ray visibility • Excellent temperature response • Compatible with all commonly available radio

frequency generators for cardiac arrhythmia ablation

OSYPKA CERABLATE flutter® for …

Atrium • FAT(r/l)/EAT • Atrial Flutter • AVNRT • AFIB

Ventricle • RVOT/LVOT • VT

Atrium and Ventricle

• WPW • AVRT

OSYPKA „CERABLATE cool®“

OSYPKA „CERABLATE cool®“

OSYPKA has developed an irrigated ablation catheter with an special TIP-design, for more safety and effectiveness during ablation procedures.

OSYPKA „CERABLATE cool®“ Key features:

• Force for manipulating the catheter tip can be adjusted individually

• Superior handling characteristics • Highly effective TIP-construction with 25-irrigation holes • Excellent torque control • Optimal curve stability • Good x-ray visibility • Excellent temperature response for more safety • TIP Size: 3,5 mm (gold)

OSYPKA „CERABLATE cool®“ Key features:

• Diameter 7F • Spacing 2-5-2 mm or 1-4-1 mm • Curve diameter 30, 45 or 60 mm • Length 110 cm • Temperature sensor: thermocouple • Compatible with all commonly

available radio frequency generators for cardiac arrhythmia ablation

TIP-Design

TIP-Design

TIP-irrigation

OSYPKA CERABLATE cool® for …

Atrium • FAT(r/l)/EAT • Atrial Flutter • AVNRT • AFIB

Ventricle • RVOT/LVOT • VT

Atrium and Ventricle

• WPW • AVRT

OSYPKA „DESTINO“

The OSYPKA DESTINO is a next generation bi-directional steerable guiding sheath for the introduction and placement of diagnostic and therapeutic devices into the human vasculature, including but not limited to intracardiac, transseptal, and other placements.

OSYPKA „DESTINO“ Key features:

• Variants in 8.5F, 10F & 12F (Inner diameter) • Bidirectional 180°(symmetric) • Curve diameters 17, 22 or 50 mm • Usable Length 71 cm or 67 cm • Soft, atraumatic tip with radiopaque marker • Hydrophobic coated sheath for improved access • Braided Flexsteer™ shaft provides exceptional steering • Lockable handle provides control and high comfort • Reliable hemotasis valve

OSYPKA „DESTINO“ Key features:

• Dilatator with 50°curve and depth markings • Maximum compatible guidewire 0.038”/0.97 mm • Compatible with all commonly available ep-devices

Contact

If you have further questions do not hesitate to contact me. Contact details: Michael Braun Product Management OSYPKA AG Tel: +49 (7623) 7405-206 Fax: +49 (7623) 7405-213 Mobil: +49 (160) 473 4323 Mail: m.braun@osypka.de