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Dr.T.V.Rao MD Professor of Microbiology INFECTION CONTROL DR.T.V.RAO MD 1

Infection control, Hospital Infections

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Infection control, Hospital Infections

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DR.T.V.RAO MD 1

Dr.T.V.Rao MD

Professor of Microbiology

INFECTION CONTROL

DR.T.V.RAO MD 2

A TRIBUTE TO IGNAZ SEMMELWEISS (1818-1865)

Ignaz Semmelweiss (1818-1865)

• Obstetrician, practised in Vienna

• Studied puerperal (childbed) fever

• Established that high maternal mortality was due to failure of doctors to wash hands after post-mortems

• Reduced maternal mortality by 90%

• Ignored and ridiculed by colleagues

DR.T.V.RAO MD 3

• Hospital-associated infections represent a serious and growing health problem. The Centers for Disease Control and Prevention (CDC) estimates that 2 million people acquire hospital-associated infections each year and that 90 000 of these patients die as a result of their infections. A variety of hospital-based strategies aimed at preventing such infections have been proposed.

HOSPITAL INFECTIONS ARE EMERGING CHALLENGES IN HEALTH CARE

DR.T.V.RAO MD 4

WHAT IS INFECTION CONTROL• Infection control is the discipline concerned with

preventing nosocomial or healthcare-associated infection. As such, it is a practical (rather than an academic) sub-discipline of epidemiology. It is an essential (though often under-recognized and under-supported) part of the infrastructure of health care. Infection control and hospital epidemiology are akin to public health practice, practiced within the confines of a particular health-care delivery system rather than directed at society as a whole.

DR.T.V.RAO MD 5

BEGINNING OF HOSPITAL INFECTION PROGRAMME

• Modern hospital infection control programs first began in the 1950s in England, where the primary focus of these programs was to prevent and control hospital-acquired staphylococcal outbreaks. In 1968, the American Hospital Association

published "Infection Control in the Hospital," the first and only standards available for many years.

DR.T.V.RAO MD 6

BEGINNING OF ACCREDITATION • In 1969, the Joint

Commission for Accreditation of Hospitals--later to become the Joint Commission on Accreditation of Healthcare Organizations (JCAHO)--first required hospitals to have organized infection control committees and isolation facilities.

DR.T.V.RAO MD 7

CDC INITIATES HOSPITAL INFECTION BRANCH

• In 1972, the Hospital Infections Branch at the CDC was formed and the Association for Practitioners in Infection Control was organized. By the close of the decade, the first CDC guidelines were written to answer frequently asked questions and establish consistent practice.

DR.T.V.RAO MD 8

• Decreasing reimbursement

• Increasing emerging infections

• Increasing resistant organisms

• Increasing drug costs

• Institute of Medicine Report--healthcare-associated infections

• Nursing shortage

• OSHA safety legislation

• Multiple benchmark systems

• FDA legislation on reuse of single-use devices

INFECTION CONTROL CHALLENGES OF HEALTHCARE IN 2000

DR.T.V.RAO MD 9

WHY EVERYONE CONCERNED WITH HOSPITAL INFECTIONS

• The Centers for Disease Control (CDC) estimates that 2 million U.S. patients a year acquire hospital-related infections. These infections cost an average of $47,000 per patient to treat and cause 90,000 deaths each year. The added cost to hospitals is $4.8 billion annually in extended care and treatment.

DR.T.V.RAO MD 10

• Every infection control program should develop a well-defined written plan outlining the organizational philosophy regarding infection prevention and control. The plan should take into account the goals, mission statement, and an assessment of the infection control program. It should include a statement of authority, and should review patient demographics including geographic locations of patients served by the healthcare system

DEVELOPING INFECTION CONTROL PROGRAMME

DR.T.V.RAO MD 11

SURVEILLANCE

• The surveillance is the cornerstone of the infection control practice because it allows to identify the areas where the outcomes are below expectations and we can improve.• Examples of centrally driven surveillance

include MRSA bacteraemia surveillance

DR.T.V.RAO MD 12

KEY ELEMENTS OF SURVEILLANCE

• Defining as precisely as possible the event to be surveyed (case definition)

• Collecting the relevant data in a systematic, valid way

• Consolidating the data into meaningful arrangements

• Analyzing and interpreting the data

• Using the information to bring about changeadapted from R. Haley

DR.T.V.RAO MD 13

• The key to ongoing monitoring is surveillance for nosocomial infections. Various techniques for surveillance have been described and evaluated including total house surveillance, targeted surveillance, Kardex, or laboratory-base

SURVEILLANCE

DR.T.V.RAO MD 14

AREAS OF INTEREST TO A HEALTHCARE

EPIDEMIOLOGIST• Surveillance for

nosocomial infection

• Patterns of transmission of nosocomial infections

• Outbreak investigation

• Isolation precautions

• Evaluation of exposures

• Employee health

• Disinfection and sterilization

• Hospital engineering and environment• water supply

• air filtration

• Reviewing policies and procedures for patient care

DR.T.V.RAO MD 15

EDUCATIONAL PSYCHOLOGY• Most difficult part of infection control practioners is

overcome the reluctance of humans to change their behaviour

• Every one knows importance of hand hygiene and sterile technique

• However hand hygiene compliance is poor among health care workers and even after intensive education and improved marginally

DR.T.V.RAO MD 16

• Education programs for employees and volunteers are one method to ensure competent infection control practices. It is a unique challenge since employees represent a wide range of expertise and educational background. The ICP must become knowledgeable in adult education principles and use educational tools and techniques that will motivate and sustain behavioral change.

STAFF TRAINING IN ICP

DR.T.V.RAO MD 17

ORGANIZING FOR INFECTION CONTROL

• Requires cooperation, understanding and support of hospital administration and medical/surgical/nursing leadership

• There is no simple formula:• Every facility is different

• Every facility’s problems are different

• Every facility’s personnel are different

• The facility must develop its own unique program

DR.T.V.RAO MD 18

• WHONET is a free Windows-based database software developed for the management and analysis of microbiology laboratory data with a special focus on the analysis of antimicrobial susceptibility test results.

DOCUMENT ANTIBIOGRAMS WITH WHONET

DR.T.V.RAO MD 19

• It carries considerable interest in implementing and monitoring interventions to optimize prescribing of antimicrobial drugs

ANTIBIOTIC STEWARDSHIP

DR.T.V.RAO MD 20

DR.T.V.RAO MD 21

• Antibiotic policies may be introduced primarily to reduce total Antibiotic use to reduce in appropriate prescribing

• Many using the most broad spectrum drugs in the first line ?

CAN WE CHANGE THE SITUATION?

DR.T.V.RAO MD 22

USE OF ANTIBIOTIC POLICIES • It has been estimated that up to 50 % of

the antimicrobial prescribing is inappropriate in terms of choice, duration and indication of treatment.

• The coordination of clinician and microbiologist to reduce in implementation of antibiotic guidelines carries a higher importance.

DR.T.V.RAO MD 23

ALERT MICROBES • Hospital acquired alert organisms generally

those organisms that have resistance to a range of antibiotics and are capable of spreading

• Methicillin resistant Staphylococcus aureus

• Gram negative bacilli resistant to gentamicin, extended spectrum beta lactamases

• Vancomycin resistant Enterococci

DR.T.V.RAO MD 24

ALL ISOLATES • All positive isolates clinical isolates from high

risk areas Intensive care areas Intensive care areas special care baby units

• Positive clinical isolates from sites of interest to infection control team ( catheter related infections,

• Urinary and Intravascular operative samples

• Removed prosthesis, heart valves , artificial joints.

DR.T.V.RAO MD 25

• ESKAPE bacteria— Enterococcus faecium, Staphylococcus aureus, Klebsiella species, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species—are among the biggest threat of infectious diseases physicians face today,

ESKAPE - BACTERIA

DR.T.V.RAO MD 26

• According to the latest data from the Centers for Disease Control and Prevention (CDC), the six ESKAPE bacteria are responsible for two thirds of all health care-associated infections (HAIs).

ESKAPE BACTERIA ARE MAJOR NOSOCOMIAL AGENTS

DR.T.V.RAO MD 27

WHAT IS BEST FOR HAND HYGIENE• A single application of 60 – 70 % Ethanol or

Isopropanol with emolument and with or with out antiseptic like

• 1 Chlorhexidine

• 2 Povidone –iodine

• Triclosan

• Proved to be more effective than soap and water

DR.T.V.RAO MD 28

• A volume of 3 ml is pored into cupped hands and rubbed to dryness

HOW YOU RUB YOUR HANDS

DR.T.V.RAO MD 29

• Do not forget to a preliminary wash with soap or detergent and water is required before the application of Alcoholic solution

IF YOUR HANDS ARE SOILED

DR.T.V.RAO MD 30

WHY WE NEED COMPUTERS • The use of technology rather than manual system

should enable data to be Analysed more easily and encouraged.

• So many soft wares in market

• But should be compatible with clinical laboratory system and integrate with hospital information technology patient management system in order to obtain with meaningful data with minimal effort.

DR.T.V.RAO MD 31

INFECTION CONTROL PROGRAMME AND DOCUMENTATION

• Goals of the infection control program need to be incorporated into the mission statement of the facility. A mission statement should tell who you are, what you do, and should communicate a clear view of purpose and set a strategy for accomplishing the goal

DR.T.V.RAO MD 32

GOOD HOUSE KEEPING A BOON TO INFECTION CONTROL

DR.T.V.RAO MD 33

BREAK THE CHAIN OF INFECTIONS

• 1. Organisms that can cause infection are subject to risk assessment under the COSHH regulations and Management of Health and Safety at Work Regulation 1992.

DR.T.V.RAO MD 34

THE INFECTION CONTROL TEAM• Consist of at least an

infection control practitioner who should be trained for the purpose; carry out the surveillance programme; develop and disseminate infection control policies; monitor and manage critical incidents; coordinate and conduct training activities.

DR.T.V.RAO MD 35

INVOLVEMENT OF PHYSICIANS MORE IMPORTANT

Physicians to be more involved and lead quality improvement efforts in their respective healthcare settings. Drs. Pronovost and Marsteller suggest that even though quality improvement efforts exist, there is not enough data supporting the notion that quality improvement efforts are actually enhancing patient outcomes. One of the reasons for this lack of progress, they say, is inadequate physician engagement and leadership in quality improvement work.

Peter Pronovost, MD, PhD, and Jill Marsteller, PhD, MP

DR.T.V.RAO MD 36

• The major responsibilities for ICPs to oversee include surveillance, specific environmental monitoring, continuous quality improvement, consultation, committee involvement, outbreak and isolation management, regulatory compliance and education. To plan, coordinate, and succeed in fulfilling these responsibilities, many ICPs have to redefine their roles. More ICPs are becoming managers by creating multidisciplinary support teams to carry out many of the functions.

MAJOR RESPONSIBILITIES OF I C P

DR.T.V.RAO MD 37

Physicians to be more involved and lead quality improvement efforts in their respective healthcare settings. Drs. Pronovost and Marsteller suggest that even though quality improvement efforts exist, there is not enough data supporting the notion that quality improvement efforts are actually enhancing patient outcomes. One of the reasons for this lack of progress, they say, is inadequate physician engagement and leadership in quality improvement work.

Peter Pronovost, MD, PhD, and Jill Marsteller, PhD, MP

INVOLVEMENT OF PHYSICIANS MORE IMPORTANT

DR.T.V.RAO MD 38

GUIDELINES AND RECOMMENDATIONS

• Hand washing and Hospital Environmental Control * Immunization * Infectious Diseases Control * Intravascular Device-Related Infections and its control

* Isolation Precautions

DR.T.V.RAO MD 39

SCIENTIFIC DOCUMENTATION REDUCES HOSPITAL INFECTIONS

• Researchers evaluated the effect of an electronic medical record on the use of antimicrobial agents and infection rates of Clostridium difficile and MRSA. Results showed that implementation of an EMR significantly increased chart reviews and antimicrobial recommendations, leading to a decrease in antimicrobial use and MRSA as well as C. difficile infection rates.

DR.T.V.RAO MD 40

A SAYING APPLIES TO ALL ACTIVITIES INCLUDING HOSPITAL SURVEILLANCE

• If you are not measuring it, you are

not managing it.

DR.T.V.RAO MD 41

• Programme Created by Dr.T.V.Rao MD for Health awareness on Hospital

acquired Infections• Email

[email protected]