Genetic testing in breast cancer
Genetic testing in breast cancer
Christina applegate
Introduction:
Hereditary Breast & Ovarian Cancer Syndrome (BRCA)
What is the purpose of our normal BRCA genes?
Background
Identification of high risk individuals
Genetic testing
Red Flags for Hereditary Breast and Ovarian Cancer Syndrome
Red Flags for Women & Men who do not have Cancer
Family history considerations:
Brca1 and brca2
Identifying brca 1/2 carriers:
Cancer risks:
Newer considerations:
NCcn guideline for management of brca 1/2 carrier:
Genetic Testing
Psychosocial considerations
Gina legislation
Summary:
Tp 53
Identifying Li Fraumeni Syndrome
Cancer risks in lfs
Cowden syndrome (phosphate and tensin homolog)
Other genetic mutations and breast cancer
Lynch syndrome and MYH associated polyposis
Categories of genes associated with hereditary and ovarian
breast cancer
Rachel, age 40 no cancer
Rachels Test result
Rachel-- Ovarian Recommendations
Rachel Breast Recommendations
Rachel Family Recommendations
Heather, age 38
Heather
Heather
Conclusion:
