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Genetic Test for Breast Cancer

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Eastern Biotech is offering predictive test for Breast Cancer.

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Page 1: Genetic Test for Breast Cancer

deCODE Breast CancerTM

deCODE Breast CancerTM identifies 7 widely replicated genetic variants (SNPs) that are associated with increased risk of developing common breast cancer, independent of familyhistory. These SNPs contribute to the incidence of anestimated 60 percent of all breast cancers. It is a novel, noninvasive, DNA-based reference laboratory test that offers physicians the opportunityto begin screening or initiate early treatment in those who are at increased risk.

BRCA 1 and BRCA 2 CommonMutation

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BreastSafe® TestThis special logic-based profiling test improves thesensitivity of breast cancer diagnosis by identifyingthe lumps at a very early stage before any symptomsappear.

Her 2 Gene AmplificationWomen with HER2-positive breast cancer (not passed to

the family) have a more aggressive disease, greater

likelihood of recurrence, poorer prognosis, and decreased

survival compared to women with HER2-negative breast

cancer. It is thus an important diagnosis for the treatment of

breast cancer.

OncotypeDX Breast Cancer AssayOncotype DX ® is a diagnostic assay that quantifies the likelihood of

breast cancer recurrence in women with newly diagnosed, early stage

breast cancer. It is validated for use in breast cancer patients whose

disease is:

l Newly diagnosed

l Stage I or II

l Node-negative

l Estrogen receptor-positive

Oncotype DX offers clinical experience information for newly

diagnosed women who are post-menopausal and have node positive,

estrogen receptor positive breast cancer and who will be treated with

tamoxifen.

Comprehensive Genetic AnalysisBreast Cancer

BRCA 1 a n d BRCA 2 a r e t h e p r ima r y g e n e sresponsible for the hereditary breast cancers. Statisticssugge s t tha t up to 10% of br e a s t c anc e r s a r ehereditary. Patients who have a strong family historyof early-onset breast cancer in multiple first-degreerelatives are often tested for the common mutations inthe BRCA 1 and BRCA 2 genes.

Eastern Biotech & Life SciencesP.O.Box 212671, Dubai, UAE. Tel: +971 4 369 2061 Fax: +971 4 363 1923

email:[email protected] visit: www.easternbiotech.com

EASTERN BIOTECH& l i f e s c i e n c e s