Drugs banned in indiaTHESE ADVERSE EFFECTS ARE DETECTED THOUGH A PROCESS OF REGULAR MONITORING AFTER THE DRUG IS RELEASED INTO THE MARKET CALLED PHARMACOVIGILANCE

If the adverse effects are severe or the risks of using the drug outweigh the benefits or ineffective , the drug may voluntarily withdrawn from the country. Some drugs may cause the side effect only when combined with particular drugs. In such cases, only the fixed dose combination is banned and not the individual drugs.

Drugs used in obesity and weight loss

FENFLORAMINE .DEXFENFLURAMINE

formation of fibrous tissue in the heart, and pulmonary hypertension

RIMONABANTdepression, suicidal tendencies and seizures

NON-STEROIDAL PAINKILLER

RAFECOXIB VALDECOXIB

They claim to relief the pain without causing stomach ulcers unlike the aspirin, however they tend to increase the heart attack and

stroke in patients taking the drugs.

Anti-allergy drugs

ASTEMIZOLE TERFENADINE

Both are antihistamines but linked to cause problem with the heart rhythm.

Antidiabetes drugs

PHENFORMINEIt cause lactic acidosis – increase Ph in the

blood.

ROSIGLITAZONEIts associated with risk of heart attack

Gastrointestinal drugs

CISAPRIDECause abnormal heart rhythms when used with

erythromycin and ketoconazole

TEDASERODRisk of heart attack and stroke.

antibiotic

GATIFLOXACINIt cause high blood sugar levels

when taken orally or iv.However eye drops containing

gatifloxacin is available.

NEW DRUG COMBINATION BANNED IN INDIA

NIMESULIDE + DICLOFENAC NIMESULIDE + CETRIZINE + CAFFEINE PARACETAMOL + CETRIZINE + CAFFEINE OMEPRAZOLE + PARACETAMOL + DICLOFENAC NIMESULIDE + PARACETAMOL (IV, SUS, DIS tab, HEPARIN + DICLOFENAC PARACETAMOL + DICLOFENAC + MAGNESIUM TRISILICATE(antacid N) AZITHROMYCIN + CEFIXIME