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  • 1.Acute Respiratory Distress Syndrome Alice Gray, MD Duke University Medical Center March 21, 2007

2. Objectives

  • Define ARDS and describe the pathological process
  • Know causes of ARDS, and differential diagnosis
  • Understand specific challenges in mechanical ventilation of patients with ARDS
  • Understand treatment strategies and evidence behind them

3. ARDS

  • First described 1967 by Ashbaugh and colleagues
  • Severe lung injury characterized by non-cardiogenic pulmonary edema, decreased lung compliance, refractory hypoxemia
  • 1994 Consensus Definition
    • Acute onset (