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ABOUT US Annual Conference Kasr Al-Ainy Faculty of Medicine Cairo Univ 22 nd April, 2012 1 Dr. Nelly Abulata Lecturer of Clinical Pathology MD, MBA, DTQM

About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

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Our Aim was to bridge the gap between us and other departments through highlighting who the ClinChem dept is, what it does and how it does it. It shines light on some of our latest achievements during 2011 in the areas of Teaching & Training, Research & Laboratory Services.

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Page 1: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

ABOUT US

Annual Conference Kasr Al-Ainy Faculty of Medicine – Cairo Univ

22nd April, 2012

1

Dr. Nelly Abulata

Lecturer of Clinical Pathology MD, MBA, DTQM

Page 2: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

I. Faculty & staff

II. Education

III. Research

IV. Patient care

Page 3: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Faculty & Staff

Page 4: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Prof. Safaa Al-Karaksy

CHAIR OF THE CLINICAL & CHEMICAL

PATHOLOGY DEPARTMENT

Page 5: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Mission

“Is to provide excellence in Laboratory services, Teaching, Training, and Research activities”.

Page 6: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Organizational Changes

6

1. Plans, organization charts and job descriptions

2. Operational issues & Projects were monitored, analyzed, evaluated and reported.

3. Website, Data base and Annual progress reports for the Department

4. Deputies to the Chair:

Scientific Research

Teaching & Training

Examination

5. Executive Committees:

Laboratory Executive Committee

Blood Bank Executive Committee

Conference Organizing Committee

2 Quality Assurance Committee; 1 Lab service, 1 Education

Scientific Research Committee

Page 7: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Organizational Chart 7

Chairman of the Board of the Clinical & Chemical Pathology

Department

Head of the Clinical

Pathology

Internal Medicine

Lab

Japanese Lab

Abou Elrish Lab

Maternity Hospital

Lab. 4th Floor

Lab

Head of the Chemical Pathology

Psychiatry Lab.

French Lab.

King Fahd Lab.

Sharm ElSheikh Hospital

ER Hospital

Lab

Manial Labs

Blood Bank

Haematology

Immunology

Microbiology

Cytogenetics

Molecular

Routine

Hormones

Electrolytes

Proteins

Oncology & Nuclear

Medicine Lab

Page 8: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Organogram (2011-2012) 8

Laboratory

Head of Lab.

(Technical)

Lab Director

(Administrative)

Head of

Hematology

Unit

Head of

Immunology

Unit

Head of

Genetics unit

Head of the

Molecular Unit

Head of

Microbiology

Unit

Manial

Clinical

Pathology

Lab.

Prof. Dr.

Mervat Al-

Ansary

Prof. Dr. Mona

Salah Prof. Dr.

Naguib

Zoheir

Prof. Dr.

Mervat Al-

Ansary

Prof. Dr. Hala

Farawella

Prof. Dr. Mona

Salah

A. Prof. Dr.

Nada Nawar

Laboratory Head of Lab.

(Technical)

Lab Director

(Administrative)

Head of

Trace

Elements

Unit

Head of

Chemistry

Routine Unit

Head of

Proteins Unit

Head of

Hormones Unit

Manial Chemical

Pathology Lab.

Prof. Dr. Fatma

El-Mougy

Prof. Dr.

Badawy Al-

Khouly

Prof. Dr.

Badawy Al-

Khouly

Prof. Dr.

Lamia

Mansour

Prof. Dr. Sahar

Abdel-Atty

Prof. Dr. Nadida

Gohar

Main Lab at Manial Hospital

Page 9: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Laboratory Head of Lab.

(Technical)

Lab Director

(Administrative)

Head of

Hematology

Head of

Immunology

Head of

Microbiology

Head of Chemical

Pathology

Internal Medicine

Hospital Lab.

Prof. Dr.

Sahar Kamal

Dr. Magda Negm

Prof. Dr. Sahar

Kamal

Dr. Mohamed

Abdulمah

A. Prof. Dr. Nahla

Fawzy

Japanese Hospital Lab. Prof. Dr.

Hanaa

Arnaout

A. Prof. Doha

Abdel Hamid

Prof. Dr.

Hanaa

Arnaout

Dr. Rabab El-

Hawary

A.Prof. Dr.

Mona Mohie

El-Din

Prof. Dr. Ola

ElSissy

Abou-Elrish Mounira

Hospital Lab.

Prof. Dr. Azza

Abou ElEnain

Prof. Dr. Hala

Gabr

Prof. Dr. Hala

Gabr

A. Prof. Dr.

Maha Gaafar

Dr. Hanan Madany

Specialized Hospital Lab.

(4th floor)

Prof. Dr.

Taysir Eyada

Dr. Sheriene

Abdel-Kader

Prof. Dr.

Hanaa

Arnaout

A. Prof. Aya

Nassef

Prof. Dr. Walaa

Gad

Prof. Dr. Iman

Mandour

French Hospital Lab. Prof. Dr. Laila

Hegazy

Dr. Hanan

Ibrahim

Prof. Dr.

Nabil El-

Danasoury

Prof. Dr. Nancy

ElGuindy

Prof. Dr. Amani

ElKholy

Prof. Dr. Hazem

Abou Youssef

King Fahd Hospital Lab. A. Prof. Manal Kamal

Psychiatric Hospital Lab. Prof. Dr. Badawy Al-Khouly

New ER Hospital Lab Prof. Dr. Badawy Al-Khouly

Maternity Hospital Lab. Prof. Dr.

Iman

Mandour

Assistant Prof.

Aya Nassef

TBD TBD Prof. Dr. Iman

Mandour

Sharm ElSheikh Int. Hosp. Assistant Prof. Mohamed Shehata

Blood Bank Prof. Dr.

Mervat Al-

Ansary

Dr. Sahar Azab

9

Page 10: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Manpower of 1000

318

393

62

141

89

0

50

100

150

200

250

300

350

400

450

Doctors Technologists & Technicians

Nurses Administration Cleaners

250

24 44

Faculty staff

Specialists

Residents

Page 11: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Role of the Department

Patient care

(Laboratory Service)

Research

Education

(Teaching & Training)

Page 12: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Education

Page 13: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Teaching & Training Programs

Undergraduates:

The Department provides teaching to the 6th year students

(Clinical & Chemical Pathology curriculum)

Recently we have delivered Summer training to Undergraduates

Postgraduates:

The Department is committed to providing strong and balanced teaching and training programs mainly to Postgraduate students, principally in the Master and Doctorate degrees in Clinical and Chemical Pathology tailored to each student subspecialty:

Hematology

Clinical Immunology

Clinical Microbiology

Clinical Chemistry

The Department is also partly involved in the teaching & training of Postgraduate students of other Departments enrolled in Master, Diplomas & Doctorate degrees.

Egyptian Fellowship Board training

Page 14: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Seminars & Conferences

Weekly Seminars:

Immunology: Every Sunday of the week

Hematology: Every Monday of the week

Chemical Pathology: Every Monday of the week

Microbiology: Every Tuesday of the week

Yearly:

Scientific ClinChem Conferences

1st CLINCHEM 2010 Conference" Molecular Biology: Into the future" 31st of March -2nd of April

2nd CLINCHEM 2010 Conference "Transfusion Medicine & Quality updates: Revolution not evolution" 24th of October, 2010

3rd CLINCHEM 2011 “Genetics and Tissue Engineering”, 3rd - 5th of April, 2011.

CLINCHEM 2012 Course “Regenerative Medicine” in collaboration with the University

of Toronto starting from September 2012 to May 2013 (organization in process)

Page 15: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

In collaboration with the ESLM, the

ClinChem Kasr Al-Ainy Team organized

the ESLM 2012 Conference 18-20

April 2012 at CICC

Workshops (currently running at our Labs):

Microbiology (17/4)

Parasitology (21/4)

Stem cells (22/4- 24/4)

DNA sequencing (22/4- 24/4)

Page 16: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

2011 Training workshops

“Screening metabolic disorders by Tandem Mass Spectrometry” Workshops

Organized via a collaboration between the Chemical Pathology team (Prof. Dr.

Fayza A Hassan Prof. Dr. Fatma El-Mougy Prof. Dr. Sahar Abdel-Atty Prof. Dr. Iman

Mandour A. Prof. Dr. Marian Morgan Dr. Dina Mehaney Dr. Mohammed A. Monem)

and the Pediatric Endocrinology team at Pediatric Hospital.

2 workshops Infection Control Team (Lead Prof. Amani Al-Kholy & her team A.

Prof. Mervat Gaber Al-Anainy, A.Prof. Mona Mohieddin Abdel Halim, Dr. Mariam

Adel, A. Lecturer Mai Sherief) in collaboration with:

NAMRU-3 on: Practical Approach to prevention of Healthcare associated

infections in Cairo University Hospitals

NAMRU-3, USAID, CDC and Cornell University on: Advanced training on

Infection prevention and control

Page 17: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Research

Page 18: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

According to our Research plan

Key research subjects

1. HCV

2. Stem Cell Research

3. Neurodegenerative diseases

4. Infection prevention and control

5. Molecular basis of Hematological disorders

6. Juvenile Diabetes Mellitus.

Page 19: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

2011 Research Awards

1. Prof Heba Abdel Razik has won:

The National Egyptian Promotional Award

The Cairo University Encouragement Award

2. Prof. Dr. Hala Gabr won the “University Award for

the Highest impact factor”

Page 20: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

2011 Research Projects & Grants

2. STDF grant:

1. "Stem Cell Therapy in End stage liver cell failure". (Principle investigator: Prof. Dr. Hala Gabr)

2. "Phase I-II clinical trial autologous dendtritic cell vaccine in patient with acute myeloid leukemia in remission. (Principle investigator: Prof. Dr. Mervat Al-Ansary)

3. Cairo University grant:

1. "Isolation and identification of Limbal Stem Cells“ (Co-investigator Prof. Dr. Hala Gabr)

2. "Study of the pluripotent stem cell potential of Peripheral blood mononuclear cells “ (Principal Investigator Prof. Dr. Mervat Al-Ansary)

4. Joint projects:

1. NAMRU-3 project “Study of the sentinel surveillance for severe respiratory illness (SARI) (Project Manager: Prof. Dr Amani El Kholy)

2. NAMRU-3, USAID & Cornell University National project: “ Quality improvement and patient safety (Project Coordinator: Prof. Dr Amani El Kholy)

1. Several projects received funding from the Faculty

Page 21: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

International Publications in 2011

>20

Paper Title Research Team Journal Name

Impact

factor

FcgRIIa and FcgRIIIa genetic

polymorphisms in a group of

pediatric immune

thrombocytopenic purpura in

Egypt

Tayseer K. Eyada, Hala M. Farawela,

Mervat M. Khorshied, Iman A. Shaheen,

Neama M. Selim and Iman A.S. Khalifa

Blood

Coagulation

and Fibrinolysis

1.4

Association of C46T genetic

polymorphism of coagulation

factor XII with deep venous

thrombosis: a cohort study on

Egyptian patients

Naguib M. Zoheir, Mona S. Hamdy,

Mervat M. Khorshied, Nelly N. Abulata,

Mehry El Sobky, Amr M. Saleh, Hussein

M. Khairy

Comp Clin

Pathol

0.3

Quantitative Assessment of Wilms

Tumor 1 (WT1) Gene Transcripts in

Egyptian Acute Lymphoblastic

Leukemia Patients

Hoda Ali Sadek, Wafaa Hassan El-

Metnawey, Iman Abdel-Mohsen

Shaheen, Mervat Mamdouh Korshied,

Azza Sobieh Mohamed

Journal of

Investigative

Medicine

1.598

Page 22: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Paper Title Research Team Journal Name

Impact

factor

Mannose binding lectin (MBL2) gene

polymorphism in sickle cell anaemia: an

Egyptian study

Menat Allah Kamal El Deen,

Mervat M. Khorshied, Zeinab A.

El Sadani, Yasmine M. Amrousy,

Nermeen M. Galal

Comp Clin

Pathol

0.3

CD200 Expression in B-Cell Chronic

Lymphoproliferative Disorders

Nermeen Ahmed El Desoukey,

Reham Abd Aleem Afify, Dalia

Gamil Amin, Rasha Faragaly

Mohammed,

Journal of

Investigative

Medicine

1.536

Clinical and laboratory evaluation of

patients with end-stage liver cell failure

injected with bone marrow-derived

hepatocyte-like cells

Amer ME, El-Sayed SZ, El-Kheir

WA, Gabr H, Gomaa AA, El-

Noomani N Hegazy M

Eur J

Gastroenterol

Hepatol

1.598

Limb salvage using intramuscular injection

of unfractionated autologous bone marrow

mononuclear cells in critical limb ischemia:

a prospective pilot clinical trial

Gabr H, Hedayet A Imam U,

Nasser M

Exp Clin

Transplant

0.6

Page 23: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Paper Title Research Team Journal Name

Impact

factor

Effect of stem cell therapy on

amiodarone induced interstitial

lung fibrosis in albino rats

Zaghloul S, Zickri M,Abd El Aziz

D, Mabrouk D, Gabr H

Int J Stem Cells

Autologous Mesenchymal Stem

Cell Therapy for Spinal Cord

Injury: Long Term Safety and

Clinical Efficacy

Gabr, Hala; Ghannam,

Osama; Awad, Mohamed

Reda; von Wild, Klaus; El-Kheir,

Wael Abo; Ewes, Ibrahim

American Journal

of Neuroprotection

and

Neuroregeneration

Viability and neural

differentiation of mesenchymal

stem cells derived from umbilical

cord following perinatal asphyxia

Aly H, Mohsen I,Badrawi N,

Gabr H, Ali Z, Akmal D

Journal of

Perinatology

2.003

Tumor necrosis factor

alpha−308 and Lymphotoxin

alpha+252 genetic

polymorphisms and the

susceptibility to non-Hodgkin

lymphoma in Egypt

Azza Ibrahima, Hala Abdel

Rahmana, Mervat

Khorshieda, Rania Samia,

Nelly Nasra, Ola Khorshid

Leuk Res 2.33

Page 24: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Paper Title Research Team Journal

Name

Impact factor

Do Serum Angiopoietin-1, Angiopoietin-2,

and Their Receptor Tie-2 and 4G/5G

Variant of

PAI-1 Gene Have a Role in the Pathogenesis

of Preeclampsia?

Manal Kamal and

Waleed El-Khayat

Journal of

Investigative

Medicine,

1.536

Phase II Trial: Undifferentiated Versus

Differentiated Autologous Mesenchymal Stem

Cells Transplantation in Egyptian Patients with

HCV Induced Liver Cirrhosis

Mervat El-Ansary, Iman

Abdel-Aziz, Sherif

Mogawer, Samah Abdel-

Hamid, Olfat Hammam,

Salwa Teaema, Marwa

Wahdan

Stem Cell

Rev and Rep

3.76

Page 25: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Paper Title Research Team Journal

Name

Impact

factor

Flow cytometric detection of

leukemic stem cells (LSCs) in

Egyptian pediatric B-acute

lymphoblastic leukemia

Manal W. El-Masry,

Mervat M. Khorshied

Iman A. Shaheen, Nelly

N. Abulata & Tarek A.

Hashem

Comp Clin

Pathol

0.3

Mesenchymal stem cells expanded

in human platelet lysate display a

decreased inhibitory capacity on T

and NK proliferation and function

AbdelRazik H.,

Spaggiari GM,

Chiossone L., Moretta L.

Eu J Immu 4.942

Direct contact of umbilical cord

blood endothelial progenitors with

living cardiac tissue is a

requirement for vascular tube-like

structures formation

Lupu M, Khalil M,

Iorache F, Andrei E,

Pfannkuche K,

Spitkovsky D,

Baumgarrtner S, Rubach

M, Abdel Razik H

J Cell Mol

Med

4.608

Page 26: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Paper Title Research Team Journal

Name

Impact

factor

Antimicrobial Resistance in Pathogens

causing Nosocomial Bloodstream

Infections in University Hospitals

Tamer Saied, Amany El

kholy, Soad F. Hafez, Hadia

Basim, Momtaz O. Wasfy,

Waleed El-Shoubary,

Ahmed Samir, Guillermo

Pimentel and Maha Talaat

Am J Infect

control.

3.077

Prospective study of healthcare-

associated bloodstream infections in

pediatric intensive care units in Cairo

University Hospitals

Amani El Kholy, Mariam

Younan.

Arab Society

for

Laboratory

Medicine.

0.697

Assessment of the role of

paraoxonase gene polymorphism

(Q192R) and paraoxonase activity

in the susceptibility to atherosclerosis

among lead-exposed workers.

Manal Kamal, Mona M

Fathy, Eman Taher, Manal

Hasan, May Tolba

Annals Of

Saudi

Medicine.

Page 27: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

This is the First Edition of the Eastern Mediterranean

Acute Respiratory Infection Surveillance (EMARIS) 27

Participants from our Dept.

Lead by Prof. Amani ElKholy

Infection control team

Partnership between

CDC's Egypt Global Disease Detection and Response Center (GDDRC)

U.S. Navy Medical Research Unit No. 3 (NAMRU-3),

the WHO Office of the Eastern Mediterranean (EMRO

With the support of the

World Health Organization (WHO),

U.S. Centers for Disease Control Prevention (CDC),

U.S. Department of State, and the U.S. Department of Defense.

Network Bulletin!

Page 28: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Patient care

Page 29: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Laboratory services

Our Laboratories provide an extensive menu of routine & specialized laboratory tests to the patients who seek care at Kasr Al-Ainy Hospitals.

Lab Specialties

Hematology Laboratory

Clinical Immunology & Molecular Diagnostics

Clinical Microbiology

Clinical Chemistry

Working Hours:

8am-2pm at the Main Labs at the Hospitals

2pm-8am through the Emergency Labs

Lab tests we provide

(www.clinchemcairo.org)

Page 30: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

2011 Annual Productivity

4.5million tests 30

(318) 4,598,604

(142) 1,888,911

(65) 1,058,813

(16) 595,114 (24)

550,338 (30) 363,137

(24) 170,949

(2) 142,291

0

1,000,000

2,000,000

3,000,000

4,000,000

5,000,000

6,000,000

Total Manial French Japanese Internal Medicine

Abou ElRish 4th floor King Fahd

Tota

l no. of

test

s &

Doct

ors

Laboratory

Page 31: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Kasr Al- Ainy lab in the 1940’s

Page 32: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Hematology Laboratory

Cell Counters Unit Coagulation Unit

Page 33: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Hematology (Manial Main Lab)

Page 34: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Immunology Laboratory

ELISA unit

Axym Unit

Page 35: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Cytogenetics Laboratory

Karyotyping Unit

Flowcytometry unit

Page 36: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Molecular Diagnostics Laboratory

PCR unit

Page 37: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Microbiology Laboratory

Working area Verification area

Page 38: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Chemistry Laboratory

Hormones Unit

Chemistry routine Unit Trace elements Unit

Page 39: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012

Contact us 39

[email protected]

www.clinchemcairo.org

Page 40: About the Clinical & Chemical Pathology Department (Annual Kasr Al Ainy Conference-Cairo University)- 22nd April 2012