THE PROTEINS ARE ESSENCIAL IN THE NORMAL FUNCTION OF THE BODY:

Formed by amino-acids. Some of their functions are:

•Enzymatic•Hormones•Structure•Immunity•Contraction•Transportation•Homeostasis•Etc.

THE ABSENCE OF SOME PROTEINS

ORIGINATE DIFFERENT DISEASES

““SBP researchers identify molecular SBP researchers identify molecular switch that controls genes needed to switch that controls genes needed to

repair skeletal muscle”repair skeletal muscle”    IN MUSCULAR DISEASES

THE STEM CELLS OF THE MUSCLE DON´T WORK

IT CAN´T REPAIR THE NORMAL MUSCLE

DAMAGES

IT HAPPENS IN THE DYSTROPHY, CANCER

AND AGING

““SBP researchers identify molecular switch that SBP researchers identify molecular switch that controls genes needed to repair skeletal muscle”controls genes needed to repair skeletal muscle”

Researches of the Sanford

Burnham Prebys Medical Research

Institute 

Identify the TBP-containing

TFIID-Protein complex

These elements are transcription factors, they take part of the

pre- initiation complex of the RNA

polymerase II

Important in the muscle

regeneration

““SBP researchers identify molecular switch SBP researchers identify molecular switch that controls genes needed to repair that controls genes needed to repair skeletal muscle”skeletal muscle”

The TBP-containing

TFIID-Protein complex

Molecular switches To the genes of

the stem cells of the muscle

““SBP researchers identify molecular SBP researchers identify molecular switch that controls genes needed to switch that controls genes needed to repair skeletal muscle”repair skeletal muscle”

Although they show the essential task of the TBP-containing

TFIID-Protein complex , they also prove that the protein that were

being studying TBP2 is not important In the muscle regeneration,

the cells participate in the reparation process of the muscle without

the TBP2.

Are you sure ??

OPINION

The dystrophies are not very common disease, but

the aging and the mutations such as the cancer are

so frequently in now days, this aspects carry me to

think that this research is going to be an important

topic in this time and in the future. The better thing

that a man could have is the life, be away from the

death, and it is the result of this investigation, it

gives hope of live to the men.

““Study identifies FGF21 protein as Study identifies FGF21 protein as potential therapeutic agent for potential therapeutic agent for

cardiovascular diseases, type 2 cardiovascular diseases, type 2 diabetes”diabetes”

 

Researches of Umeå University showed how the FGF21 redistribute

fatty acids by two ways

FGF21 is fibroblast grow factor , it´s member of an endocrine subfamily

FGF21 is a potential therapeutic element to treat the obesity´s

diseases such as type 2 diabetes

““Study identifies FGF21 protein as potential therapeutic Study identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes”agent for cardiovascular diseases, type 2 diabetes”

““Study identifies FGF21 protein as potential Study identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 therapeutic agent for cardiovascular diseases, type 2 diabetes”diabetes”

LPL

Activated in

Muscle

Adipose tissue

Function

Hydrolytic cleavage

Uptake of blood lipids

““Study identifies FGF21 protein as potential therapeutic Study identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes”agent for cardiovascular diseases, type 2 diabetes”

The objective of the investigation is to gives tools to develop new treatments to people that suffer

obesity related health problems, a treatment that stimulates the LPL

could reduce the signs and symptoms of the diseases type 2

diabetes and cardiovascular problems.

OPINION

What do you think?

The obesity and the diseases related with this are common diseases in now days, the men don´t learn to control themselves in the food and it´s an investigation that help the humanity to fight against the trouble. The medicine have to be updated in the world, and this is the evidence.

THE MOST IMPORTANT THING IN A INVESTIGATION IS THE UTILITY THAT

WE CAN GIVE THEM IN THE REAL LIFE, IN THIS CASE IN THE MEDICINE

MEDICAL UTILITY

MEDICAL UTILITY

A lot of people have fall in the mistake of eat and eat,

it´s the origin of the obesity´s diseases, that in this

time are very common, but here is the medicine, the

investigation, to give the a second opportunity to

have a better life style and enjoy in the short life. Our

science have to be updated and continue saving lives.

MEDICAL UTILITY Like we have seen in this presentation, the

proteins are good options to treatments in

all the world, it´s a big support to the

medicine and the humanity, helping as to

find the cure to different and hard diseases

such as the cancer, dystrophies, obesity,

type 2 diabetes and cardiovascular troubles.

of this way the protein contributes to have a

better life each day (in some cases).

BIBLIOGRAPHY· Umea University. Study identifies FGF21 protein as potential therapeutic agent for

cardiovascular diseases, type 2 diabetes [Internet]. News-Medical.net; 2016 [access

February 12 of 2016]. Avaible in: http://www.newsmedical.net/news/20160211/Study-

identifies-FGF21-protein-as-potential-therapeutic-agent-for-cardiovascular-diseases-

type-2-diabetes.aspx

Published on February 11, 2016

· Sanford-Burnham Prebys Medical Discover Institute. SBP researchers identify

molecular switch that controls genes needed to repair skeletal muscle [internet]. News-

Medical.net; 2016 [access February 12 of 2016]. Available in: http://www.news-

medical.net/news/20160211/SBP-researchers-identify-molecular-switch-that-controls-

genes-needed-to-repair-skeletal-muscle.aspx

Published on February 11, 2016