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Page 1: Viruses, Viroids, and Prions - …loulousisbiology.weebly.com/uploads/2/1/9/3/21932052/viruses_notes.pdfcopyright cmassengale . 14 Helical Viruses copyright cmassengale . 15 Polyhedral

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Viruses

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What are Viruses?

A virus is a non-cellular particle made up of genetic material and protein that can invade living cells.

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Discovery of Viruses Beijerinck

(1897) coined the Latin name “virus” meaning poison

He studied filtered plant juices & found they caused healthy plants to become sick

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Viewing Viruses

Viruses are smaller than the smallest cell

Measured in nanometers

Viruses couldn’t be seen until the electron microscope was invented in the 20th century

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Size of Viruses

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Are Viruses Living or Non-living?

Viruses are both and neither They have some properties of

life but not others For example, viruses can be

killed, even crystallized like table salt However, they can’t maintain a

constant internal state (homeostasis). copyright cmassengale

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Viral Structure

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Characteristics

•Noncellular

•Contain a protein coat called the capsid

•Have a nucleic acid core containing DNA or RNA

•Capable of reproducing only when inside a HOST cell

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Characteristics

•Some viruses are enclosed in an protective envelope •Some viruses may have spikes to help attach to the host cell •Most viruses infect only SPECIFIC host cells

CAPSID

ENVELOPE

DNA

SPIKES

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Characteristics

•Viral capsids (coats) are made of individual protein subunits

•Individual subunits are called capsomeres

CAPSOMERES

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Characteristics

•Outside of host cells, viruses are inactive

•Lack ribosomes and enzymes needed for metabolism

•Use the raw materials and enzymes of the host cell to be able to reproduce

EBOLA VIRUS

HIV VIRUS

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Characteristics •Some viruses cause disease •Smallpox, measles, mononucleosis, influenza, colds, warts, AIDS, Ebola •Some viruses may cause some cancers like leukemia

MEASLES

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Viral Shapes

•Viruses come in a variety of shapes

•Some may be helical shape like the Ebola virus

•Some may be polyhedral shapes like the influenza virus

Others have more complex shapes like bacteriophages

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Helical Viruses

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Polyhedral Viruses

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Complex Viruses

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