WebQuest: Name ______________________Introduction to Respiration

A. http://www.phschool.com/science/biology_place/labbench/lab5/intro.html1. Cellular respiration occurs in most cells of both plants and animals. It takes place in the ___________________, where energy from nutrients converts _______ to _______. 2. ATP is used for all cellular activities that require _______________.

3. Go to the next screen and write a word equation for respiration:

4. Go to the next screen - Grasshopper “closer look” - describe what is happening when the grasshopper respires.

B. http://dwb.unl.edu/Teacher/NSF/C11/C11Links/www.harcourtcollege.com/chem/biochem/GarrettGrisham/HardToGrasp/Redox/Redox.html1. How OIL RIG is going to help you remember the definitions of Oxidation and Reduction.

C. http://www2.wwnorton.com/college/biology/discoverbio3/full/content/ch8/animations.asp1. Click on 8.1a: View the animation and sketch a picture that depicts the process of photosynthesis.

2. Click on 8.2a: View the animation of Glycolysis. Where does Glycolysis occur in cells? _________________

Electrons are donated to ___ molecules of NAD+, generating 2 molecules of ___________.

In glycolysis, there is a net energy yield of ___ ATP and ___ NADH molecules. How many ATP molecules are needed for glycolysis to happen? How many ATP molecules are made by glycolysis?

3. Click on 8.2b: View the animation of Krebs Cycle (Citric Acid Cycle). Before the Krebs Cycle, the pyruvate molecule is split into ___________ (released) and

________________ (the high energy molecule that enters the Krebs Cycle). How many carbons does pyruvate have? ____ How many carbons does Acetyl CoA have? ____ Where does the Kreb Cycle occur in cells? ______________________ In the Krebs Cylce (Citric Acid Cycle) a 4-Carbon compound called _____________ is

combined the 2-C compound called ________________ to make a 6-C compound called ________________.

During the Krebs Cycle, __ CO2 are released. How many carbons is that? ___ All of the carbons in the pyruvate (3-C compound) are released as _________.

3. Click on 8.2c: View the animation of Oxidative Phosphorylation. Where does Oxidative Phosphorylation occur in cells? _____________________ Donated ________________ move through the ____________________________ that

occurs through several different protein channels. What is this type of transport called (using protein channels)? ______________________________.

Electrons are donated to __________________ (the final electron acceptor) that has entered the mitochondrial matrix through the process of ____________________. Oxygen then combines with protons (H+) to form _______________.

Draw a picture of frame 6, labeling all of the parts shown in the picture

D. http://www.sp.uconn.edu/~terry/Common/respiration.html1. Where does respiration occur in prokaryotes (bacteria)?2. Click go, then animate – Food is the electron _________________ and Oxygen is the

electron _______________. 3. During respiration the disposal product of food (glucose) is ________________.4. During respiration the disposal product of water is _____________________.

E. http://www.bbc.co.uk/schools/gcsebitesize/teachers/biology/activities.shtmlClick on “Chemical Reactions during Respiration”

1. Write the equation for Respiration

2. Describe in words what happens to the glucose molecule.

F. http://www.phschool.com/science/biology_place/biocoach/cellresp/overview.html1. Glycolysis occurs in the _____________________.2. The Krebs cycle takes place in the __________________ of the ________________________.3. Oxidative phosphorylation via the electon transport chain is carried out on the _____________________________.

4. Fill in the words for A-H in the following diagram.

5. Fill in what the result of Glycolysis is (at the end of the arrows).

6. Fill in what the result of Krebs Cycle is (at the end of the arrows)

G. http://staff.jccc.net/pdecell/cellresp/respintro.html1. Fill in the number of ATP, NADH, FADH2 and CO2 in the diagram below

H. http://www.biosci.uga.edu/metabolism/overview1.html - Watch the AnimationsGlycolysis1. Glycolysis means _________________________. 2. During Glycolysis enzymes break a 6-carbon ______________ into _______ 3-carbon _________________.3. What 3 things go into Glycolysis? ____________________________________4. What are the 3 products of Glycolysis? _________________________________5. Does Glycolysis require oxygen? ______________________________________6. What must be present for glycolysis to begin? ______________________________7. What does NADH do?

Click on Krebs Cycle1. The Krebs cycle takes materials made during glycolysis and turns them into

______________ and ________________, which contain the ________________ used to fuel the last phase of metabolism in which large amounts of ATP are produced.

2. Why are mitochondria so important to a cell? _____________________________________________________________________________________________________3. click on “Evolution of Mitochondria” – where do scientists think mitochondria came

from?

4. What evidence do scientists have to prove that?

5. The Krebs Cycle turns ___ times for each glucose molecule that goes through respiration.

6. The main role of the Krebs Cycle is to produce __________ and ______________, the high energy molecules that carry the electrons which will be used to make ATP.

7. For every molecule of glucose that enters the Krebs Cycle, what is produced?

Click on Electron Transport (Oxidative Phosphorylation)1. The two main parts are the:

Electron Transport Chain which produces ______________ Chemiosmosis which produces ____________________

2. The two “taxicabs” are _________ and __________ which take their “passengers” the ________________ to _____________________________________________. The passengers jump from cab to cab to get to their destination, the final electron carrier: ___________.

3. What is the importance of breathing in the process of respiration?4. During the Electron Transport Chain, H+ went from __________________ to

_________________________ and build up like a dam. ________________ is the name of the enzyme that acts like a “turbine” to get H+ rapidly into the inner membrane of the mitochondria, which creates energy to change ADP + P to ____________________.

5. Summary of Electron Transport PhosphorylationInputs Outputs

6. The Electron Transport System is located where? _________________________

7. The final electron receptor for cellular respiration is _______________________8. What is the direct source of ATP generation during the Electron Transport

Phosphorylation?____________________________________________________________

I. ATP synthase turbine - http://www.sp.uconn.edu/~terry/Common/respiration.html1. For every ____H+ that get pushed through the cell membrane ____ ATPs are produced.

J. http://www.sp.uconn.edu/~terry/images/anim/ETS.htmlGreat animation of Electron Transport Chain (Oxidative Phosphorylation)

Best for Class LCDStart with thishttp://www.qcc.cuny.edu/BiologicalSciences/Faculty/DMeyer/respiration.html

Oxidation - Reductionhttp://dwb.unl.edu/Teacher/NSF/C11/C11Links/www.harcourtcollege.com/chem/biochem/GarrettGrisham/HardToGrasp/Redox/Redox.html

http://www.wiley.com/legacy/college/boyer/0470003790/animations/animations.htm

What the molecules look like for all 3 steps:http://www.johnkyrk.com/indexkaleido7x7.eng.swf John Kyrk

Reducing/OxidizingETC – step by step animationhttp://science.nhmccd.edu/biol/etc/respirat.html

Aerobic AND Anaerobic

Diagramhttp://www.emc.maricopa.edu/faculty/farabee/BIOBK/energpath1.gif

Glycolysis Aerobic AND ANEAROBICUse this for anaerobichttp://www.sp.uconn.edu/~terry/Common/respiration.html

Aerobic and anaerobic respiration animations: http://www.sp.uconn.edu/~terry/Common/respiration.html

http://instruct1.cit.cornell.edu/Courses/biomi290/MOVIES/GLYCOLYSIS.HTML

http://www.sp.uconn.edu/~terry/images/anim/ETS_slow.html

http://fig.cox.miami.edu/~cmallery/150/metab/c9x6cell-respiration.jpg

GlycolysisThere are 4 important stages in glycolysis:

• Activation of glucose by ATP

• Splitting of glucose into two roughly equivalent phosphorylated halves

• Reduction of NAD+ to NADH

• Phosphorylation of ADP

1. Whole Process and Enzymes2. Overall Reaction Dr. Meyer at CUNY3. Metabolic Pathways Wisconsin Online4. Cellular Respiration Thomas M. Terry at Univ. of Conn.5. Enzyme Tutorial from Northland Community and Technical College 6. Enzyme Pathways McGraw-Hill7. Enzyme Activity Lew-Ports Biology Place8. Enzymologie by Laurent Martorell Académie de Créteil9. Enzyme Reaction - Simulation BBCi10.Enzyme Kinetics Wiley11.Enzyme Inhibition Wiley

12.Glycolysis13.Gylcolysis by Sue Merkel, Cornell Univ (BEST) 14.Glycolysis by RM Chute15.Glycolysis by John Kyrk16.Anaerobic Respiration-Glycolysis and Fermentation by Sue Merkel, Cornell Univ17.Glycolysis Animation from Northland Community and Technical College 18.Glycolysis Donald Nicholson19.Acetyl CoA and Krebs (TCA)(Citric Acid) Cycle20.Virtual Cell's Educational Animations MCBE 21.TCA (Citric Acid) Cycle by Rodney F. Boyer22.Citric Acid Cycle Purdue University23.Fatty Acid Respiration Campbell Interactive Chemistry24.The Pruvate Dehydrogenase Complex Campbell Interactive Chemistry25.Acetyl CoA and Krebs Cycle by June B. Steinberg26.Oxidative Phosphorylation27.ATP Synthase Gradient: The Movie Virtual Cell28.ATP Synthase Movie Thomas M. Terry at Univ. of Conn.29.ATP Synthesis (ATPase) Flash Animation Carnegie Mellon30.Production of ATP by Oxidative Phosphorylation 31.Electron Transport by June B. Steinberg32.Oxidative Phosphorylation Campbell Interactive Chemistry33.Oxidative Phosphorlyation (advanced) Nature Reviews Molecular Cell Biology 34.Electron Transport McGraw-Hill35.Electron Transport by Rodney F. Boyer 36.Oxidative Phosphorylation Purdue University37.

ab includes a worksheet.

Back to the topLinks

Aerobic and anaerobic respiration animations: http://www.sp.uconn.edu/~terry/Common/respiration.html

Aerobic respiration tutorial: http://www2.nl.edu/jste/aerobic_respiration.htm ATP and biological energy tutorial:

http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookATP.html ATP to ADP animation: http://www.biologyinmotion.com/atp/index.html Respiration and photosynthesis animations:

http://www.science.smith.edu/departments/Biology/Bio231/  Cellular metabolism and fermentation:

http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookGlyc.html  Good photosynthesis animation:

http://www.web.virginia.edu/gg_demo/movies/figure18_12b.html  Glycolysis animations: http://science.nhmccd.edu/biol/glylysis/glylysis.html 

Celluar respiration animation: http://instruct1.cit.cornell.edu/courses/biomi290/ASM/glycolysis.dcr

Good narrated animation of photosynthesis: http://www.fw.vt.edu/dendro/forestbiology/photosynthesis.swf

Photosynthesis animation: http://www2.kumc.edu/netlearning/examples/flash/photosyn2.html 

Production of ATP by oxidative phosphorylation animations: http://science.nhmccd.edu/biol/etc/respirat.html 

Fermentation animation: http://instruct1.cit.cornell.edu/Courses/biomi290/MOVIES/GLYCOLYSIS.HTML

Good outline of cellular respiration and photosynthesis  from Kim Rebello.  The structure of mitochondria vs chloroplasts:

http://w3.dwm.ks.edu.tw/bio/activelearner/08/ch8c1.html  PowerPoint presentation on photosynthesis:

http://sun.sunyrockland.edu/~kbaker/photo.ppt Another good photosynthesis animation: http://www.johnkyrk.com/photosynthesis.html 

Good photosynthesis animations with audio: http://highered.mcgraw-hill.com/sites/0072437316/student_view0/chapter10/animations.html#

PS Workbook/ Tutorial http://www.nclark.net/photosynthesis.pdf

Activities at this website: http://www.nclark.net/PhotoRespiration

Do this "Investigating Photosynthesis and Respiration through Kinesthetics and Inquiry"  activity.

Use this "Photosynthesis / Cell Respiration / Enzymes / Light" Jeopardy Game  with instructions.

Try this Flinn "Respiration versus Photosynthesis"  activity. Have students do this "Energy in a Cell"  crossword puzzle. Or do this "Energy in a Cell" wordsearch puzzle  with answers  . "The Demise of the Halloween Pumpkin" would be a great activity to start around

Halloween.  This is an ongoing activity that will last aproximately 3 months.  The activity measures energy use, but teaches about setting up controlled experiments and about the decomposing activity of microorganisms. 

Use this "Photosynthesis"  tutorial with questions for students to answer. Using the Cells Alive website, Maria Ferraro contributed this "The Cell Cycle and

Animal Cell Mitosis"  worksheet. Play the "Come On Down (The Electron Transport Chain)" song performed by Sam

Reid.  (To save the song you can right-click on the link and select "Save Target As.") Use this "Jeopardy PowerPoint: Photosynthesis / Cell Respiration / Enzymes / Light" to

review for quizes.

Play this Quia battleship "Glycolysis" game. "The Effects of Light Intensity and Wavelength on the Rate of Photosynthesis" is an

activity that uses this photosynthesis animation.

Back to the topLabs

The "Burning Peanuts Laboratory"  reveals the energy stored in food and includes a student guide  .

The "Effects of a Closed Environment on Living Things" lab demonstrates how plants use carbon dioxide and produce carbon and how animals use oxygen and produce carbon dioxide.

This "Do Plants Consume or Release CO2? Or Both?" lab demonstrates how plants carry on both photosynthesis and respiration.

The "Rate of Photosynthesis" lab explores just that. Do the "Leaf Pigment Chromatography" lab  . This lab  compares the production of starch in leaves kept in the light and those in the

dark. This "Fermentation by Yeast" lab  can be used in this unit or with the study of

microorganisms.  This is an image of the lab report for this lab done by one student group.

"Photosynthesis:   A Controlled Experiment " illustrates the effect of differing amounts of carbon dioxide on photosynthesis in geranium plants.  Coleus or other similar plants could just as easily be used.

"The Energy Content of Food Laboratory"  is another activity for determining the calories in food and includes a teacher's guide  .

In "The Heat is On - The Energy Stored in Food" students will burn several types of nuts and snack foods in order to determine their heat content per gram.

In Kim Rebello's "Every Breath You Take" lab students investigate whether animals and plants carry on respiration.

Make a homemade calorimeter to determine "The Energy in Food" . This "Waterweed Simulation" is a worksheet to acompany "The Waterweed Simulator."

Students count the bubbles released by Elodea to determine which color of light is more effective for photosynthesis.  (Since Elodea is hard to come by these days, this is a good alternative.)

 This "Plant Respiration" lab  uses seedlings and a bromothymol blue solution to demonstrate that plants give off CO2 during respiration.

In "Studying the Effect of Photosynthesis and Respiration on Aquatic Chemistry" students use microcosms and RUSS data to investigate changes in oxygen concentrations that result from photosynthesis and respiration.  The lab includes a worksheet.

Back to the top

Links Aerobic and anaerobic respiration animations:

http://www.sp.uconn.edu/~terry/Common/respiration.html Aerobic respiration tutorial: http://www2.nl.edu/jste/aerobic_respiration.htm ATP and biological energy tutorial:

http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookATP.html ATP to ADP animation: http://www.biologyinmotion.com/atp/index.html Respiration and photosynthesis animations:

http://www.science.smith.edu/departments/Biology/Bio231/  Cellular metabolism and fermentation:

http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookGlyc.html  Good photosynthesis animation:

http://www.web.virginia.edu/gg_demo/movies/figure18_12b.html  Glycolysis animations: http://science.nhmccd.edu/biol/glylysis/glylysis.html  Celluar respiration animation:

http://instruct1.cit.cornell.edu/courses/biomi290/ASM/glycolysis.dcr Good narrated animation of photosynthesis:

http://www.fw.vt.edu/dendro/forestbiology/photosynthesis.swf Photosynthesis animation:

http://www2.kumc.edu/netlearning/examples/flash/photosyn2.html  Production of ATP by oxidative phosphorylation animations:

http://science.nhmccd.edu/biol/etc/respirat.html  Fermentation animation:

http://instruct1.cit.cornell.edu/Courses/biomi290/MOVIES/GLYCOLYSIS.HTML Good outline of cellular respiration and photosynthesis  from Kim Rebello.  The structure of mitochondria vs chloroplasts:

http://w3.dwm.ks.edu.tw/bio/activelearner/08/ch8c1.html  PowerPoint presentation on photosynthesis:

http://sun.sunyrockland.edu/~kbaker/photo.ppt Another good photosynthesis animation: http://www.johnkyrk.com/photosynthesis.html 

Good photosynthesis animations with audio: http://highered.mcgraw-hill.com/sites/0072437316/student_view0/chapter10/animations.html#    

Great timing! I just had a test on cellular respiration... Here are a few good web sites...

http://www.sp.uconn.edu/~terry/images/anim/ATPmito.html

Animations of ATP production in the mitochondria. Thomas Terry of the University of Connecticut has created excellent animations of electron transport and the ATP synthease enzyme. These animations help to explain how electron transport generates an electrical gradient that provides the energy necessary to produce ATP. Click on the various links for different animations.

http://www.sp.uconn.edu/~terry/images/anim/ETS.html

Animations of electron transport in the mitochondria. You may reach this animation using links from the first address, since this is another animation produced by Thomas Terry.

http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookGlyc.html

Cellular metabolism and fermentation. This chapter of M.J. Farabee’s excellent online textbook will help you learn about both aerobic and anaerobic respiration.

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/CellularRespiration.html

A summary of the process of cellular respiration.

http://www2.nl.edu/jste/electron_transport_system.htm

Electron transport system. Hit the play buttons at the corners of the diagrams to view some nice animations. This is a really good visual representation of electron transport and chemiosmosis.

http://www.bact.wisc.edu/microtextbook/Metabolism/Fermfoods.html

Fermentations of Importance to Humans. Examples of, and a brief discussion of how to make, some of the products of fermentation.

http://www.goaskalice.columbia.edu/0818.html

Muscle soreness and weightlifting. Alice explains why your muscles produce lactic acid and how you can avoid lactic acid production when weightlifting.

http://www.stolaf.edu/people/giannini/flashanimat/metabolism/mido%20e%20transport.swf

Another animation of electron transport. I can’t get enough of these. I am including so many illustrations of this concept because it is very important. Plus, these are neat to watch. Hit the GO button in the lower left corner to start the show.

http://www.jonmaber.demon.co.uk/glyintro/

Introduction to glycolysis. Go to the questions at the bottom and click on each one. You can use the arrows at the top of each question page to proceed. Lots of information here if you can work your way through the site. I found that the Quicktime animations worked better on my computer.

http://www.ruf.rice.edu/~bioslabs/studies/mitochondria/mitopoisons.html

Use of metabolic poisons to study mitochondrial function. A brief list of poisons that inhibit mitochondrial functioning.

http://www.gwu.edu/~mpb/

Metabolic pathways of biochemistry. While in more detail than your text, this site presents you with excellent three-dimensional rotatable images of carbohydrate metabolism (glycolysis, Krebs cycle…), lipid metabolism, protein metabolism, and chemiosmosis (oxidative phosphorylation). I had some trouble connecting to the 3-D plug-ins.

http://old.jccc.net/~pdecell/cellresp/respoverview.html

Overview of cellular respiration. You can click on various regions of the map for a more detailed explanation of that component of cellular respiration.

http://instruct1.cit.cornell.edu/Courses/biomi290/MOVIES/GLYCOLYSIS.HTML

The miracle of fermentation. You will need Macromedia’s Shockwave player to view this animation on lactate (lactic acid) fermentation.