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Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)

The following table is a listing of the new, revised, and deleted codes in the Drug Testing, Therapeutic Drug Assay, and Chemistry sections that will be effective January 1, 2015.

If an applicant or other interested party believes an action of the CPT Editorial Panel was in error, that individual or entity may submit a code change application to the CPT Editorial Panel. The application and instructions may be obtained by visiting the AMA website. An “interested party” is an individual or entity that may potentially be impacted by the Panel’s decision, regardless of whether they participated in the Panel’s original consideration of the matter.

Note: Permanent code numbers are not assigned, nor exact wording finalized, until just prior to publication. Codes that contain an 'X' (eg, 1002X4, 234X2X, 0301XT) are placeholder codes that are intended, through the first three digits, to give readers an idea of the proposed placement in the code set of the potential code changes. These codes are not used for claims reporting and will be removed and not retained when the final CPT Datafiles are distributed on August 31st of each year. To report the services for 'X' codes, please refer to the actual codes as they appear in the CPT Datafiles publication distributed on August 31st of each year.

Detailed information regarding these codes including, guidelines, parenthetical notes, rationales and clinical examples will be available with the August 31

st release of the CPT code set data files and

subsequent educational materials, including CPT Changes 2015: An Insider’s View. You may learn more about obtaining these materials by visiting amastore.com.

▲80100 Drug screen, qualitative; multiple drug classes chromatographic method, each procedure

80101 single drug class method (eg, immunoassay, enzyme assay), each drug class

(For qualitative analysis by multiplexed screening kit for multiple drugs or drug classes, use 80104)

#80104 multiple drug classes other than chromatographic method, each procedure

80102 Drug confirmation, each procedure

80103 Tissue preparation for drug analysis

801XXX1 Drug screen, any number of drug classes from Drug Class List A; any number of non-TLC devices or procedures, (eg, immunoassay) capable of being read by direct optical observation including instrumented-assisted when performed (eg, dipsticks, cups, cards, cartridges), per date of service

801XX2A single drug class method, by instrumented test systems (eg, discrete multichannel chemistry analyzers utilizing immunoassay or enzyme assay), per date of service

801XX4A Drug screen, presumptive, single drug class from Drug Class List B, by immunoassay (eg, ELISA) or non-TLC chromatography without mass spectrometry (eg, GC, HPLC), each procedure

801XXX6 Drug screen, any number of drug classes, presumptive, single or multiple drug class method; thin layer chromatography procedure(s) (TLC)(eg, acid, neutral, alkaloid plate), per date of service

801XXX7 not otherwise specified presumptive procedure (eg, TOF, MALDI, LDTD, DESI, DART), each procedure

801XY1 Alcohols

801XY2 Alcohol biomarkers; 1 to 2

http://www.ama-assn.org/go/cpt-application

https://commerce.ama-assn.org/store/


801XY3 3 or more

801XY44 Alkaloids, not otherwise specified

801XY18 Amphetamines, 1 to 2

801XY19 3 to 4

801XY20 5 or more

801XY44A Anabolic steroids 1-2

801XY44B 3 or more

801XY28 Analgesics, non-opioid; 1 to 2 drugs

801XY29 3 to 5

801XY30 6 or more

801XY22 Antidepressants, serotonergic class; 1 to 2 drugs

801XY23 3 to 5

801XY24 6 or more

801XY25 Antidepressants, tricyclic and other cyclicals; 1 to 2 drugs

801XY26 3 to 5

801XY27 6 or more

801XY27A Antidepressants, not otherwise specified

801XY34 Antiepileptics, not otherwise specified; 1 to 3 drugs

801XY35 4 to 6

801XY36 7 or more

801XY31 Antispychotics, not otherwise specified; 1 to 3 drugs

801XY32 4 to 6

801XY33 7 or more

801XY4 Barbiturates

801XY5 Benzodiazepines; 1-12

801XY6 13 or more

801XY12 Buprenorphine

801XY37 Cannabinoids, natural

801XY38 Cannabinoids, synthetic 1 to 3

801XY39 4 to 6

801XY40 7 or more

801XY43 Cocaine

801XY13 Fentanyl

801XY13B Gabapentin, non-blood

801XY9 Heroin metabolite


801XY9A Ketamine and norketamine

801XY10 Methadone

801XY17B Methylenedioxyamphetamines (MDA, MDEA, MDMA)

801XY17C Methylphenidate

801XY7 Opiates, one or more

801XY15 Opioids and opiate analogs; 1 to 2

801XY16 3 to 4

801XY17 5 or more

801XY8 Oxycodone

801XY13A Pregabalin

801XY7A Propoxyphene

801XY7B Sedative hypnotics (non-benzodiazepines)

801XY14 Skeletal muscle relaxants; 1-2

801XX14A 3 or more

801XY41 Stimulants, synthetic

801XY42 Tapentadol

801XY48 Tramadol

801XY17A Stereoisomer (enantiomer) analysis, single drug class

801XY45 Drug(s) or substance(s), definitive, qualitative or quantitative, not otherwise specified; 1 to 3

801XY46 4 to 6

801XY47 7 or more

80152 Amitriptyline

80154 Benzodiazepines

80160 Desipramine

▲80162 Digoxin; total

80XXX13 free

▲80164 Dipropylacetic acid (valproic acid) Valproic acid (dipropylacetic acid); total

80XXX11 free

80166 Doxepin

▲80171 Gabapentin, whole blood, serum or plasma

80172 Gold

80174 Imipramine

80182 Nortriptyline

#84228 Quinine


80196 Salicylate

▲80299 Quantitation of therapeutic drug, not elsewhere specified

82000 Acetaldehyde, blood

82003 Acetaminophen

82055 Alcohol (ethanol); any specimen except breath

82101 Alkaloids, urine, quantitative

82145 Amphetamine or metaamphetamine

82205 Barbiturates, not elsewhere specified

82520 Cocaine or metabolite

▲82541 Column chromatography/mass spectrometry (eg, GC/MS, or HPLC/MS), non-drug analyte not elsewhere specified; qualitative, single stationary and mobile phase

▲82544 stable isotope dilution, multiple analytes, quantitative, single stationary and mobile phase

82646 Dihydrocodeinone

82649 Dihydromorphinone

82651 Dihydrotestosterone (DHT)

82654 Dimethadione

82666 Epiandrosterone

82690 Ethchlorvynol

82742 Flurazepam

82980 Glutethimide

83840 Methadone

83858 Methsuximide

83887 Nicotine

83925 Opiate(s), drug and metabolites, each procedure

84022 Phenothiazine

▲84600 Volatiles (eg, acetic anhydride, carbon tetrachloride, dichloroethane, dichloromethane, diethylether, isopropyl alcohol, methanol)


Drug Class A

Alcohol (Ethanol)

Amphetamines

Barbiturates

Benzodiazepines

Buprenorphine

Cocaine metabolite

Heroin metabolite (6-monoacetylmorphine)

Methadone

Methadone metabolite (EDDP)

Methamphetamine

Methaqualone

Methylenedioxymethamphetamine (MDMA)

Opiates

Oxycodone

Phencyclidine

Propoxyphene

Tetrahydrocannabinol (THC) metabolites (marijuana)

Tricyclic Antidepressants

Drug Class B

Acetaminophen

Carisoprodol/Meprobamate

Ethyl Glucuronide

Fentanyl

Ketamine

Meperidine

Methylphenidate

Nicotine/Cotinine

Salicylate

Synthetic Cannabinoids

Tapentadol

Tramadol

Zolpidem

Not otherwise specified


Definitive Drug Classes Listing

Codes Classes Drugs

801XY1 Alcohol(s) Acetone, Ethanol, ethchlorvynol, ethylene glycol, isopropanol, isopropyl alcohol, methanol

801XY2-801XY3

Alcohol Biomarkers

Ethanol conjugates (ethyl glucuronide [ETG], ethyl sulfate [ETS], fatty acid ethyl esters, phosphatidylethanol)

801XY44 Alkaloids, not otherwise specified

7-Hydroxymitragynine, atropine, cotinine, lysergic acid diethylamide (LSD), mescaline, mitragynine, nicotine, psilocin, psilocybin, scopolamine

801XY18-801XY20

Amphetamines Amphetamine, ephedrinelisdexamphetamine, methamphetamine, phentermine, phenylpropanolamine, pseudoephedrine

801XY44A-801XY44B

Anabolic steroids 1-Androstenediol, 1-androstenedione, 1-testosterone, 4-hydroxy-testosterone, 6oxo, 19-norandrostenedione, androstenedione, androstanolone, bolandiol, bolasterone, boldenone, boldione, calusterone, clostebol, danazol, dehydrochlormethyltestosterone, dihydrotestosterone, drostanolone, epiandrosterone, epitestosterone, fluoxymesterone, furazabol, mestanolone, mesterolone, methandienone, methandriol, methenolone, methydienolone, methyl-1-testosterone, methylnortestosterone, methyltestosterone, mibolerone, nandrolone, norbolethone, norclostebol, norethandrolone, norethindrone, oxabolone, oxandrolone, oxymesterone, oxymetholone, stanozolol, stenbolone, tibolone, trenbolone, zeranol

801XY28-801XY30

Analgesics, non-opioid Acetaminophen, diclofenac ibuprofen, ketoprofen, naproxen, oxaprozin, salicylate

801XY22-801XY24

Antidepressants, serotonergic class

Citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline

801XY25-801XY27

Antidepressants, Tricyclic and other cyclicals

Amitriptyline, amoxapine, clomipramine, demexiptiline, desipramine, doxepin, imipramine, maprotiline, mirtazpine, nortriptyline, protriptyline,

801XY27A Antidepressants, not otherwise specified

Bupropion, desyenlafaxine, isocarboxazid, nefazodone, phenelzine, selegiline, tranylcypromine, trazodone, venlafaxine

801XY34-801XY36

Antiepileptics Carbamazepine, clobazam, diamethadione, ethosuximide, ezogabine, lamotrigine, levetiracetam, methsuximide, oxcarbazepine, phenytoin, primidone, rufinamide, tiagabine, topiramate, trimethadione, valproic acid, zonisamide


801XY31-801XY33

Antipsychotics Aripiprazole, chlorpromazine, clozapine, fluphenazine, haloperidol, loxapine, mesoridazine, molindone, olanzapine, paliperidone, perphenazine, phenothiazine, pimozide, prochlorperazine, quetiapine, risperidone, trifluoperazine, thiothixene, thoridazine, ziprasidone

801XY4 Barbiturates Amobarbital, aprobarbital, butalbital, cyclobarbital, mephobarbital, pentobarbital, phenobarbital, secobarbital, talbutal, thiopental

801XY5, 801XY6

Benzodiazepines Alprazolam, chlordiazepoxide, clonazepam, clorazepate, diazepam, estazolam, flunitrazepam, flurazepam, halazepamlorazepammidazolam, nitrazepam, nordazepam, oxazepam, prazepam, quazepam, temazepam

801XY12 Buprenorphine Buprenorphine

801XY37 Cannabinoids, natural Marijuana, dronabinol carboxy-THC

801XY38-801XY40

Cannabinoids, synthetic CP-47,497, CP497 C8-homolog, JWH-018 and AM678, JWH-073, JWH-019, JWH-200, JWH-210, JWH-250, JWH-081, JWH-122, HWH-398, AM-2201, AM-694, SR-19 and RCS-4, SR-18 and RCS-8, JWH-203, UR-144, XLR-11, MAM-2201, AKB-48.

801XY43 Cocaine Benzoylecgonine, cocaethylene, cocaine, ecgonine methyl ester, norcocaine

801XY13 Fentanyls Acetylfentanyl, alfentanil, fentanyl, remifentanil, sufentanil

801XY13B Gabapentin, non-blood gabapentin

801XY9 Heroin metabolite 6-acetylmorphine , acetylcodeine , diacetylmorphine

801XY7B Hypnotics, sedative (non-benzodiazepines)

See Sedative Hypnotics

801XY9A Ketamine and Norketamine Ketamine, norketamine

801XY10 Methadone Methadone and EDDP

801XY17B Methylenedioxyamphetamines MDA, MDEA, MDMA

Staff Note: AMA Staff mistakenly mislabeled assignment of “X” code to this material. The above reflects correction.

801XY17C Methylphenidate Methylphenidate, ritalinic acid

801XY9A Norketamine – see Ketamine

801XY7B Non-Benzodiazepines – see Hypnotics, sedative

801XY7 Opiates Codeine, dihydrocodeine, hydrocodone, hydromorphone, morphine

801XY15-801XY17

Opioids and opiate analogs Butorphanol, desomorphine, dextromethorphan, dextrorphan, levorphanol, meperidine, naloxone, naltrexone, normeperidine, pentazocine,

801XY8 Oxycodone Oxycodone, oxymorphone

801XY21 Phencyclidine Phencyclidine

801XY13A Pregabalin Pregabalin

801XY7A Propoxyphene Norpropoxyphene, propoxyphene


801XY7B Sedative Hypnotics Eszopiclone, Zaleplon, Zolpidem

801XY14-801XY14A

Skeletal muscle relaxants Baclofen, carisoprodol, cyclobenzaprine, metaxalone, methocarbamol, orphenadrine, tizanidide.

801XY41 Stimulants, synthetic 2C-B, 2C-E, 2C-I, 2C-H, 3TFMPP, 4-methylethcathinone, alpha-PVP, benzylpiperazine, bromodragonfly, cathinone, m-CPP, MDPBP, MDPPP, MDPV, mephedrone, methcathinone, methylone, phenethylamines, salvinorin, tryptamines

801XY42 Tapentadol Tapentadol

801XY48 Tramadol Tramadol