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Cell, Vol. 59, No. 4. November 17,1989

Positions Available

Cell Classified Information Cell publishes classified advertisements for positions available, and for announcements of meetings,

symposia, and courses. 1989 Hates are $225 for a quarter page, $425 for a half page, and $795 for a full

page. We will accept either camera-ready material or copy for typesetting. Deadlines for the next

available issues are as follows (all material due close of business on due date):

Jan. 12,199O issue: copy due Dec. 8,1989 Jan. 26,199O issue: copy due Dec. 22,1989

Feb. 9,199O issue: copy due Jan. 51990 Feb. 23,199O issue: copy due Jan. 19,199O

March 9, 1990 issue: due Feb. 2, 1996 copy March 23,1990 issue: due Feb. 16,199U copy

April 6, 1990 issue: copy due March 2, 1990 April 20, 1990 issue: copy due March 16, 1990

May 4, 1990 issue: copy due March 30, 1990 May 18,199U issue: copy due April 13, 1990

Advertisements should be sent to:

MARIE ARSENAULT

Classified Ad Department

Cell

60 Church Street

Cambridge, MA 02136 (617-661-7059) FAX Number (617-661-7961).

Head of Microbiology Department The University of Illinois

The Microbiology Department in the School of Life Sciences of the University of Illinois at Champaign-Urbana is

seeking applicants or nominations for the position of Head of the Department and Professor of Microbiology. The

Microbiology Department, which has a long record of excellence in microbiology research, consists of 20 faculty members

and 68 graduate students. Faculty members have strong, well funded research programs and represent a variety of

areas. Several openings exist for recruitment of new faculty members at all levels, and the University administration

has made a strong commitment to further development of molecular biology and biotechnology. Resources for research

include a Biotechnology Center which provides protein sequencing and nucleic acid synthesis, a Cell Sciences Center

which provides monoclonal antibodies and cell sorting, and the Center for Prokaryotic Genome Analysis. The University

also has an internationally known School of Chemical Sciences.

The Microbiology Department is responsible for providing courses in Microbiology for undergraduate and graduate

students in the School of Life Sciences and for providing instruction in medical microbiology for first and second year

medical students.

Candidates should have a Ph. D. degree in a relevant discipline, a record of outstanding achievement, well funded

research in microbiology, cell biology, or molecular biology, and the ability to work with scientists representing diverse

research areas. Inquiries, nominations, and applications should be directed to the search committee chairman:

Dr. Robert Switzer, c/o Microbiology Head Search Committee, Department of Microbiology, 131 Burrill Hall, 407 S.

Goodwin, University of Illinois, Urbana, IL 61601. (217) 333-1142. Applications should be received by December 15,

1969. Some interviews may be held before the closing date, but all applications arriving by December 15, 1989 will

receive full consideration. Salary is negotiable depending on qualifications and experience. Preferred starting date is

August 1, 1990.

The University of Illinois is an Equal Opportuni&@tRmatiative Action EmploVer and actiw3ly seeks applications from wmen and minor@ candidates.

Cell. Vol. 50, No. 4, November 17,1989

Faculty Positions Assistant/Associate Professor Department of Biochemistry

University of Illinois College of Medicine at Chicago

Applications and nominations are invited for tenure track faculty positions to be filled in the 1990 academic year. We are seeking candidates who are using modern molecular biological approaches to investigate problems in the general area of bioregulation including signal transduction/membrane interaction, growth control, and cell differentiation. Exceptional applicants in other areas will also be considered. Applicants should have a Ph. D., postdoctoral experience, a strong record of research accomplishments, and demonstrable potential for the development of an independent research program. At the tenured level, applicants must have a strong record of research accomplishments. The Department of Biochemistry consists of M full time faculty and has hired several new faculty in the areas of gene expression and membrane biology in recent years. The Department and College have research support facilities that include nucleic acid and protein synthesis and sequencing.

Applicants should include a curriculum vitae, a summary of current and future research plans and the names of at least three individuals for references. Application deadline is December 31, 1989. Send applications or nominations to:

Robert v. stortl Department of Biochemistry (M/C 838)

University of Illinois College of Medicine at Chicago

1853 W. Polk Street

Chicago, IL 80812.

The University of Illinois is an ArRmatiw Action/Equal Oppottunity Employer.

Faculty Position in Ceil Biology Carnegie Mellon University

Applications are invited for a tenure track position in the Department of Biological Sciences at Carnegie Mellon University. Applicants must be strongly motivated toward carrying out research in cell biology. Candidates who are just completing their postdoctoral research training will be considered for a position of starting assistant professor; exceptionally wellqualified

individuals may be considered for appointment at a higher level.

To apply, send curriculum vitae and a concise description of research interests (no more than three pages) and, in addition, have three letters of recommendation sent to: Dr. John Woolford, Chair, Cell Biology Search

Committee, Department of Biological Sciences,

Carnegie Mellon University, 4400 Fifth Avenue,

Pittsburgh, PA 18213. Deadlines for applications: December 15, 1989.

Carnegie Mellon Uniwwsity is an Equal Opportunity/

A177rmatitm Action Empbyer.

Available Spring 1990 in Laboratory of Dr. Claudio Basilica, Department of Pathology. Areas of research presently investigated include: 1) The regulation of expression of the K-FGF/HST oncogene, and the characterization of the growth factor it encodes. 2) The interaction of K-FGF and related growth factors with their receptor(s). 3) Cloning and characterization of genes regulating cell cycle progression in animal cells. Background in Molecular Biology, Genetics or Cell Biology desirable.

Salary open. Send CV and names of references to: Joan Harmon, Personnel Department, New York Universi NYlOOd

Medical Center, 550 First Ave., New York, . An Equal Opportunity Employer M/E

Cell, Vol. 59, No. 4. November 17,1989

Postdoctoral Fellowship Department of Therapeutic Radiology YaZa University School of Medicine

Exciting opportunity for a Ph. D. with a background in molecular biology and immunology and an interest in vascular biology or cell motility to join a vascular cell biology laboratory at Yale Medical School. Experience with recombinant DNA techniques is necessary. Current investigations center around isolation, characterization, and cloning of vascular and epithelial cell migration factor(s). Competitive salary.

Please send curriculum vitae to:

Dr. Eliot M. Rosen

Department of Therapeutic Radiology

132 HRT

vale University School of Medicine

333 Cedar Street New Haven, CT 06510.

Postdoctoral Positions in Biochemistry & Molecular Biology

Two positions available immediately to study the mechanism of action of specific deoxynucleotide metabolizing enzymes as well as the regulation of their genetic expression in eukaryotes and prokaryotes. Gene isolation and amplification of their protein products will be required. Once obtained substrate and regulatory sites on the protein products will be determined by functional group specific reagents and affinity labels. In addition site specific mutagenesis will be employed to establish the relation of structure to function in these enzymes. Cloning and sequencing experience desirable. The research will be conducted in a well-equipped oors facility. Compensation from Health Research Inc. dependent upon experience. Send resume and three references to: Dr. Frank Malay

Wadsworth Canter for Laboratories and Research Empire State Plaza

BOX509

Albany, NY 12201.

An Equal Opportun~/~irmatiw Action Employer.

Faculty Positlon in Pharmacology University of Texas Southwestern Medical Center

The Department of Pharmacology at the University of Texas Southwestern Medical Center at Dallas seeks applicants for tenure track positions at the level of assistant or associate professor. Applicants must have a relevant Ph. D. or M. D. degree and postdoctoral training and must show evidence of a firm commitment to a career in independent research. We are particularly interested in applicants who plan to apply techniques of cellular or molecular biology or biochemistry to fundamental problems of pharmacological interest. Responsibilities include teaching graduate and/or medical students after the first year of employment.

Send curriculum vitae, list of three referees, and a brief description of proposed research to: Alfred G. Gilman, Chairman, Department of Pharmacology, University of Texas Southwestern

Medical Center at Dallas, 5323 Harry Hines Blvd.,

Dallas, TX, 75235-9041. An Equal Opportunity/A#%mat Action Employer.

FACULTY POSITIONS CELL AND MOLECULAR BIOLOGY AND RETROVIROLOGY

The Department of Anatomy and Cell Biology, SUNY Health Science Center at Brooklyn, invites applications for several faculty positions, at all ranks, in an actively growing department committed to expanding its faculty in the eneral areaof molecular, cellular and neuro biol- ogy. Tf e successful candidates will be required to teach in our medical school histology/cell biology of neuro- anatomy or gross anatomy course and participate in

8.. raduate school core curriculum. We require a M.D. or h 0 degree with postdoctoral experience ar.d dem-

onstrated ability to develop an independent research pro- gram. Candidates with research interests in the area of human retroviruses, mechanisms of tissue specific gene expression, molecular biol

“3, y of muscle development,

cell surface and membrane c annels or signal transduc- tion mechanisms, are particularly encouraged to apply. Excellent laboratory facilities, start-up funds and infra- structural support and excellent environment for collabo ration amon basic and clinical investigators are available for modern lologccal work. Send Curriculum Vitae, a % statement of research goals and the names of three references to:

Dr. M.A.Q. Siddiqui Professor and Chairman Department of Anatomy & Cell Biology

slwYnurm-CEmER At BRoawN 450 Clarkson Avenue-Box #5 Brooklyn, New York 11203

EO/AA Employer DMC#CR0270

Cell, Vol. 5.9, No. 4, November 17, 1909

L

University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School Graduate School of Biomedical Sciences

NEW JERSEY

THE STATE UNIVERSITY OF NEW JERSEY

Rutgers University - Graduate School

Combined MD/PhD Program

The University of Medicine and Dentistry of New Jersey- Robert Wood Johnson Medical School and Rutgers University-Graduate School at New Brunswick/University of Medicine and Dentistry of New jersey-Graduate School of Biomedical Sciences offer a combined MD/PhD program. Students accepted into the program will receive tuition and a stipend as follows: $6,500 (1st and 2nd years), $10,000 (3rd, 4th and 5th years), and $8,000 (6th and 7th years). Full-time PhD training will normally be taken in the third year of the program.

PhD training is available in the following areas:

Biochemical and Biomedical Engineering, Biochemistry & Molecular Biology, Cell & Developmental Biology, Environmental Science, Molecular Genetics, Microbiology, Pharmacology, Physiology, Neurobiology, Public Health, and Toxicology.

The institutions that are cooperating to offer this program are the University of Medicine and Dentistry of New Jersey, Rutgers University, The Center for Advanced Biotechnology and Medicine, and the Environmental and Occupational Health Sciences Institute, all located in Piscataway, NJ.

Students will be selected on the basis of previous academic work, MCAT or GRE test scores, and letters of recommendation.

For further information and an application form, please contact the Graduate School of Biomedical Sciences, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854-5635.

Cell. Vol. 5% No. 4. November 17,lBBB

Postdoctoral Position Growth Regulation The Ohio State University

A postdoctoral position is immediately available to

study the biochemistry and developmental biology of

heparin-binding (fibroblsst) growth factor. Candidates

with interests in molecular, cellular, or developmental

biology are encouraged to apply. Experience in protein

biochemistry and the basic recombinant DNA

techniques of molecular biology is preferred.

Candidates should submit a resume, statement of past

research training, and three letters of reference to:

Dr. Ing-Ming Chiu

David Medical Research Center

Ohio State University

College of Medicine

490 West 9th Avenue

Columbus, OH 43210.

An Equal Opportunity Ernployw.

Postdoctoral Position California Institute of Technology

A postdoctoral fellowship is available at Caltech

involving instrumentation and methods development related to increasing sensitivity of protein

microsequencing. Background in biochemistry or

protein chemistry preferred. Experience in protein

sequencing, HPLC and electrophoresis desirable.

Send curriculum vitae and three letters of reference to:

Dr. Leroy E. Hood

California institute of Technology

Division of Biology, 147-7s

Pasadena, CA 91125.

NATIONAL CANCER INSTITUTE-FREDERICK CANCER RESEARCH FACILITY W-Basic Research Program

POSTDOCTORAL FELLOWSHIPS BRI-Basic Research Program Postdoctoral Fellowships are awarded

The senior staff members and their research interests are

Gemga Vands Woudez molecular basis of neoplastk transformation

TM “% e structure and function of HIV reverse transcriptase

an rntegra n protein; expression of cytoskeletal genes; retroviral vectors; transgenic birds

-T PavlakJsr eukaryotic gene r ulation; molecular mechanisms

of ce transformation; molecular bra ogy of HIV and pathogenesis 7 of AIDS Peter JeJ~nson: mammalian transcription factors; molecular basis of tissue-specific gene expression gtepbee Orodan: immunochemistry and rotein chemistry of retro- viruses; structure and funcrion of retrovira P gene products; proteases AJae Rekn retroviral genetics; functional analysis of retroviral genes using natural and synthetic mutants Nancy #a: molecular biology of retroviruses; orhzogene expression WWam l@rsky: environmental carcinogenesis; mechanisms of carcinogenesb by nitrosamines and rehted compounds Antbony DJppJe: carcinogen-DNA interactions; polycyclic aromatic hydrocarbon carcinogenesis and mutagenesis Rebert Moschek chemical synthesis of carcinogen-modified DNA;

!i2% I chemistry of carcinogen-DNA interacbons; DNA adduct-

mutagenesis in bacteria and mammalian cells

-T er MI&J& biochemistry of carcinogen activation;

DNA a ylation; chemotherapeutic agents era: enome rearrangement, recombination, and DNA

$ZiY$& ce!l type regulation

for l-3 years with stipends ranging from $24,000 to $30,OOO/year.

David Carfinkek molecular biology of the retrotransposon Tyl; insertional mutagenesis by Ty; gene regulation Amar Man gene regulation and homothallic mating-type switching in fission and budding yeast Stuart Austbn chromosome stabilii in bacteria: regulation of plasmid replication and distribution of copies to daughter cells Richard Ffshd: molecular mechanisms and biochemistry of genetic recombination in mammalian cells Donald Court: regulation of gene expression by transcriPtion initiation. transcriotion termination. and RNA urocessina Neal Cc&and: molecular genetics of murine’leukemogenesis; developmental genetics; transposable elements and retroviruses Nancy Jencnbkn: insertional mutagenesis by retroviral DNAs; transgenic mice; molecular biology of mouse development tub F. Paradar use of ES cells to study molecular biolonv of development, the role of oncogenes,.and tar eted recombination: in situ hvbridization analvsis o develooment $

homologous

Peter Donovan: development of the mouse erm line: erm cell gene expression; germ line mutations; cell a d ,f hesron mo ecules Alexander Wlodawen structure of enzymes and oncogene products studied by X-ray diiaction Irene Weben crystallographic analysis of proteins and nucleic acids; modeling of unknown protein structures; protein-l&and interactions J. Ronahi Rubku crystallographic investigations of ligand- macromolecule interactions and drug-nucleic acid interactions

Send a curriculum vitae and the names of three references to the investigator(s) of interest, c/o Dr. Maurice 1. Cuss, BRI-Basic Research Program, NCI-Frederick Cancer Research Facilii, P.O. Box B (Rm 4BA), Frederick, Maryland 21701-1013.

An euwl oo~~rtunitf/affimtive action en~lover MIFIHN

CaiI.Vol.59.No.4.Novambar 17.1989

Undergraduate Research Opportunitie! Fred Hutchinson Cancer Research Center, Seattle Summer 1990

The Division of Basic Sciences faculty invites qualified undergraduates to apply for summer research positions in molecular and cellular biology. Research in the Division’s 29 laboratories spans the entire spectrum of modern biology including cellular, molecular, developmental biology, oncogenes, genetics, molecular immunology, membrane biology, and virology.

Students are supported by fellowships from the Center. Completed applications are due February 15, 1990. For further information and application forms write: Aesociate Director Division of Basic Sciences Fred Hutchinson Cancer Research Center 1124 Columbia Street Seattle, WA 98104. Fred Hutchinson Cancer Research Center provides a smoke-free environment. The Fred Hutchinson Cancer Research Cenfer is en

Equal Oppottzmi@+ftkmetiw Action Employw.

M/F/f.

Research Associate Position Experimental Therapeutics Department Roswell Park Memorial Institute

Research Assooiate: Ph. D. in Biochemistry or Chemistry. Will conduct research in pharmacology of DNA-damaging agents in program being developed to explore relationships between drug action on cellular DNA and cytotoxicity. Studies will emphasize development of concepts designed to target DNA reactive antitumor agents towards unique populations of genomic DNA with focus on characterizations of drug-induced DNA lesions on replicating elements. 4 years Postdoctoral laboratory experience in biochemical and molecular pharmacology of DNA-damaging agents. $28K/yr. 40 hr./wk.

Send curriculum vitae and three references to: Dr. Terry Beerman Grace Cancer Drug Center Roswell Park Memorial lnrtltute Elm & Carlton Streets Buffalo, NY 14263.

ASSISTANT AND ASSOCIATE PROFESSORSHIPS IN

PATHOLOGY: CANCER RESEARCH

The Department of Pathology at the University of Tennesee Medical Center has recently made a new commitment to develop a strong academic program in cancer research. As part of this endeavor, several new positions are currently available. Applicants who have a strong interest and background in one or more of the following areas of investigation should apply:

1. Control of Cell Proliferation/Differentiation and Carcinogenesis 2. Mechanisms of Cancer Invasion and Metastasis 3. Molecular Virology and Molecular Genetics 4. Tumor Immunology

lndividuals with MD, PhD, or MD/PhD degrees with a reputation for scientific productivity are encouraged to submit their curriculum vitae and bibliography with three letters of recommendation. Preference in the selection process will be given to those applicants with current extramural research support and those who are qualified to teach graduate courses in cell and molecular pathology especially relating to disease mechanisms.

Applications will be reviewed as of January 1, 1990 and thereafter until the positions are filled. Please send applications to:

Dr. Robert E. Scott, Chairman Pathology Search Committee Department of Pathology University of Tennessee 800 Madison Avenue: Suite 576 BMH Main Memphis, Tennessee 38163

“The University of Tennessee is an equal employment opportunity/affirmative action/Title IX/Section 504 employer.”

bll. Vol. 59, No. 4. November 17, 1989

Faculty Position Department of Biological Sciences University of Pittsburgh The Department of Biological Sciences at the

University of Pittsburgh invites applications from

highly qualified individuals with strong research

commitment for a tenure track Assistant Professor

position in one of the following areas: Molecular

Genetics, Cell and Developmental Biology, Molecular

Structure. This position is one of several which will

be filled in the near future as the Department expands

its research interests in these and other areas. In

addition to establishing a vigorous research program,

the candidates will direct graduate research and participate in teaching programs. Starting date:

September 1, 1990. Applicants with a Ph. D. and

postdoctoral experience should forward a brief

description of research plans, curriculum vitae, and

arrange for three letters of recommendation to be sent

to: Faculty Search Committee, Department of

Biological Sciences, University of Pittsburgh,

Pittsburgh, PA 15260. The Uniwsity of Pittsburgh is

an Equal Oppo~unhy/ArRmatiws Action Emplopr.

Applications tivm minority and women candidaies are

especial/y encouraged.

Doctoral Studies In Biology and Molecular Biology University of Maryland

The Department of Biological Sciences of the

University of Maryland Baltimore County offers courses

of study leading to Ph. D. degrees in Biological

Sciences, Molecular and Cell Biology, and Marine

Estuarine-Environmental Studies. The research interests

of the 25 faculty of the Department include

immunology, microbiology, molecular biology of

prokaryotes and eukaryotes, plant biology, genetics, cell and developmental biology, physiology, ecology, and

evolution. The Department is equipped with state-of-

the-art facilities for modern research in biology, and is located in the most rapidly growing campus of the

University of Maryland system. Graduate research assistantships offered to incoming students include a

stipend and remission of tuition. To obtain an

application form and for further information please

write to:

Dr. Paul S. Lowtt, Chairman, Graduate Programs in

Biological Sciences, Department of Blologlcal

Sciences, Unlverslty of Maryland Baltimore County, Baltimore, MD 21228.

Post Doctoral Fellows/ Research Associates

Applications are invited for an appointment within the Manitoba Institute of Cell Biology for a Ph.D. Biochemist/Molecular Biologist to parkipate in a molecular genetic investiga- tion into the regulation of ribonucleotide reduction and DNA synthesis in mammalian cells

Applicants should send full C.V., the names, addresses and phone numbers of two references to

Dr. Jim A. Wright Manitoba Institute of Cell Biology 100 Olivia Street Winnipeg, Manitoba Canada R3E OV9

Closing date IS one month after the appearance of this advertisement Salary range is $21.500-$26,000

Both men and women are encouraged to apply In accordance with Canadian Immigration requirements priority will be given to Canadian citizens and permanent residents

Manitoba Insthute of Cell Biology

Postdoctoral Positions St. Louis University School of Medicine

Postdoctoral positions are available to work on the

function of three new, low abundance, human small

nuclear RNAs of unique nucleotide sequences, for

which we have cloned cDNAs. Interested persons may

telephone (314) 577-8488.

Applicants please send a curriculum vitae and the

addresses of three references to:

Dr. George L Ellcelri

Department of Pathology

St Louis University School of Medicine

1482 South Grand Boulevard

St Louis, Missouri 83104.

An Equal @xvtunity Employs1 M/F/H/.

Faculty Positions in Molecular Biology Southern Illinois University at Carbondale

Applications are invited for tenure track openings at the Assistant Professor level in the area of Molecular Biology/Genetics. These new 12 month appointments are part of the University’s commitment to strengthen and expand its program in molecular biology in the College of Irgriculture, College of Science, and School of Medicine. The initial openings are in the departments listed below. In addition to establishing a strong research program, teaching at the undergraduate and graduate levels is expected. All candidates must have an earned doctorate and postdoctoral experience. Salary, research facilities, and start-up funds are very competitive. Applications will be accepted by the Departments as shown below until at least January 15, 1990 or until the positions are filled. Separate applications should be forwarded if an applicant wishes to be considered for more than one unit. Chemistry and Blochemiatry A position is available in the general area of eucaryotic molecular biology. All qualified candidates will be considered but preference will be given to persons workinQ on problems associated with regulation of gene expression. Applicants should send their curriculum vitae, a statement of research plans, and have at least three letters of reference sent to: Dr. J. Tyrrell, Chairman, Chemistry and Blochemlatry, Southern Illlnola Unlveraity, Carbondale, IL 62901. Mlcroblology A position is available in the general area of molecular biology. All qualified applicants will be considered but preference will be given to those whose primary area of research interest is in some aspect of the molecular genetics of eucaryotic cells, the immune system, or host-parasite interactions. Interested applicants should send their curriculum vitae, a statement of research plans, and the names of at least three references to: Dr. John Martlnko, Search Committee, Department of Mlcroblology, Southern llllnola Llnlveralty, Carbondale, IL 62901. Plant and Soil Science A position is available in the general area of molecular/cell agronomy. All qualified candidates will be considered, but preference will be given to individuals whose primary interest is in genetic engineering of agronomic crops for increasing yield potential, e.g. to increase resistance to insects, diseases, or herbicides. To apply, send a letter of application, curriculum vitae, a statement of research plans, and have at least three letters of reference sent to: Dr. Donald Stucky, Chairman, Department of Plant and Soll Science, Southern llllnola Unlveralty, Carbondale, IL 62901. Southern Illinois at Carbondale is an Equal Opportunity/M~atiw Action Employtar.

Predoctorai Positions at M.I.T. Molecular, Chemical, & Genetic Analysis of the Chemical-Biologic Interactions Related to Cancer 81 Genetic Disease. Whitakar College of Health Sciences and Technology Graduate Program in Toxicology

John M. Eaalgmann: DNA repair and mutagenesis. James 0. Fox: Gastrointestinal microflora 8

endogenous carcinogens. Steven R. Tannenbeum: Chemistry of macromolecular

adducta; nitric oxide. Wllllam G. Thllly: Mutational spectra; mechanism

& genetic epidemiology. Gerald N. Wogan: DNA adducts & genetic change

in carcinogenesis. Helmut Zarbl: Transformation effector &

suppressor genes, oncogenes; gene expression.

Full support (stipend and tuition) Is offered to all accepted candidates. For program information and an application, contact: Debra A. Luchanln, Academic Mmlnlatrator, Dlvlalon of Toxicology, Room 16-330, M.I.T., Cembrldge, MA 02139. (617) 2534604.

Postdoctoral & Junior Faculty Atherosclerosis Research Center University of Colorado Health Sciences Center

Postdoctoral and junior faculty appointments to work in interdisciplinary group involved in molecular, cellular, and genetic aspects of lipid metabolism and atherosclerosis. Salary $18,QW to $ZMI,ooO (depending on qualifications).

Send curriculum vitae and references to: Roger Davis, Ph. D. Attwoacleroaia Research Center Unlveralty of Colorado Health Sclencea Center Box B-158 4200 East Nlnth Avenue Denver, CO 80262.

UCHSC is an Equal @po~niiy/Wkmative Action

Employer.

Cell, Vol. 59, No. 4, November 17, 1!389

SENIOR FACULTY POSITION MOLECULAR BIOLOGY

Syracuse University has initiated a program of growth and development of a strong unit in molecular biology within the Department of Biology. Several stages of recruitment that will encompass both junior and senior faculty positions are planned and new facilities, including 23,ooO square feet of research space, are under development. Applications and nominations for a senior position are invited at this time. Candidates must have a vigorous research program supported by extramural funding and a strong record of accomplishments. Areas of specialization within molecular biology are unrestricted. The successful candidate will have substantial time available for research, but participation in the instruction of undergraduate and graduate students is expected. Curriculum vitae, including a statement of career and research goals, information on research support, and three references should be sent by January 1, 1990 to: Dr. J. K. Bryan, Depertment of Biology, SYRACUSE UNIVERSITY, 130 College Place, Syracuse, NY 13244-1220. An AIfrmative Action/Equal Oppcvtunity Employer.

Postdoctoral Research Associate Molecular Genetics of CNS University of North Carolina at Chapel Hill School of Medicine

Position available immediately to apply molecular biological techniques to the study of tyrosine protein kinases in developing brain and retina, Laboratory focuses on the biological activity of src-related protooncogenes in growth cones, cell migration, and synaptogenesis. Candidate should have a Ph. D. and experience with recombinant DNA methods, cell cultures, and vertebrate embryology.

Please send curriculum vitae and names of three references by November 30,1989 to: Dr. Patricia F. Maneaa Deperbnent of Biochemistry CB# 7260,505 FLOB Univerafty of North Carolina at Chapel Hill School of Medicine Chapel Hill, NC 275997260.

Equal @portunity/M~atiw Action Employer.

Postdoctoral Fellowships Kenneth Norris Jr. Comprehensive Cancer Center/USC School of Medicine Postdoctoral fellowships (3) on NIH Training Grant in Chemical and Viral Carcinogenesis to work in laboratories of: Joaeph R. Landolph (molecular biology of chemical transformation); Peter A Jonea (tumor cell biology; DNA methylation); Predip Roy-Burman (retroviruses and oncogene alleles); Suraiya Rasheed (retroviruses and AlDS-related lymphomas); Yuen K.T. Fung (retinoblastoma); Myron Goodman (biochemical mechanisms of fidelity and SO5 repair); and Amy Lee (molecular biology: control of mammalian gene expression). Candidates must be U. S. citizens or permanent residents. Minority and women candidates strongly encouraged to apply. Send curriculum vitae, names of three individuals who can supply letter of recommendation and preference of faculty preceptors to: Dr. Joaeph R. Landolph, Kenneth Norris Jr. Comprehensive Cancer Center/USC School of Medicine, 1441 Eeatlake Avenue, Los Angeles, CA 90033. AtWmatiw Action/Equal Oppottunity

Employw.

Assistant/Associate Professor University of Rochester Cancer Center

Applications are invited for a tenure track faculty appointment in the Experimental Therapeutics Division of the Cancer Center. The appointee is expected to develop a strong research program involving the application of cellular and molecular approaches to basic and therapeutic problems in Cancer biology, Individuals with experience in DNA repair, oncogene regulation, cell cycle regulation, or molecular genetic approaches to diagnostics or therapeutics are particularly encouraged to apply. Extensive opportunities exist for interactions with other Cancer Center investigators in areas such as Immunology, Pathology, and Molecular Biology. The Cancer Center is strongly committed to the support of promising new research programs. Applicants should submit a curriculum vitae and a statement of research interests to: Dietmar W. Siemann, Ph. D., Chairman, Seerch Committee, Unlveraity of Rochester Cancer Center, Box 704,601 Elmwood Avenue, Rochester, NY 14642. The Univerdy of Rochester is an Equal Opportvnity/Mhathe Action Emplowrz

Cdl. Vol. 59. NC. 4, k4cvember 17,1989

UMDNJ-Graduate School of Biomedical Sciences Invites application to the Ph. D. Graduate Program in Molecular Genetics and Microbiology at UMDNJ-Robert Wood Johnson Medical School. Director: Sidney Pestka. Edward Arnold: X-ray crystallography of viral proteins, molecular modeling, antiviral design. Kenneth J. Breslauer: Nucleic acid structure and drug DNA binding studies. Kiron Das: lmmunopathology of ulcerative colitis, Crohn’s disease. David T. Denhardt: Regulation of cell proliferation in cancer, aQinQ. Ralph Dornburg: Betrovirus evolution; retroviral vectors in gene transfer. Joseph P. Dougherty: retrovirus replication and retrovirus vectors. Donald T. Dubin: Antibiotic resistance: HN structure and diagnosis. Joachim W. Messing: Gene expression in plants, Ml3 cloning, gene synthesis. Julian J. O’Pear: Cell cycle regulation: human Qenome structure/function. Sidney Pestka: Interferon, receptors, expression of proteins. Abbas Rashidbaigi: Interferon8 and their molecular mode of action. Yaccv Bon: Differentiation of T and B lymphocytes. R. Walter Schlesinger: Mechanisms of viral neurovirulence. Aaron J. Shatkin: Gene expression in eukaryotic cells and viruses. Stanley Stein: Synthesis and analysis of peptides and proteins. Victor Stollar: Virus-host cell interactions of arboviruses. Evelyn M. Witkin: DNA repair and induced mutagenesis in bacteria. These faculty from UMDNJ-Robert Wood Johnson Medical School and Rutgers, The State University of New Jersey, including the New Jersey Center for Advanced Biotechnology and Medicine are the nucleus of a growing graduate program. This program provides courses, and thesis research opportunities in laboratories with sophisticated instrumentation and computer access. Merit-based fellowships are available providing an annual stipend of $12,000 plus tuition. Prospective students should write to: Director of Graduata Studier, Dapartment of Mokcular Ganetks and Mkrobkkgy, UMDNJ-R&r Wood Johnaon Medkal School, 675 Hoe8 Lane, Piecataway, New Jersey 08854, for more information and an application form. The Univwt-siry is an

A~97rmaths Action/Equal Opportunity Employw.

Postdoctoral Research Position Molecular Biology Department of immunology Research institute of Scripps Clinic

A position is available immediately to study the regulation and functional significance of core protein to proteoQlycan conversion in normal and malignant cells. Approaches utilize immunochemical, biochemical, and recombinant DNA techniques. Background in protein chemistry and/or molecular biology essential.

Scripps offers outstanding research facilities in the expanding San Diego scientific community. Interested candidates should send their curriculum vitae and the names of three references to:

Robert C. Spiro, Ph. D. Research InMute of Scripps Clink 10606 North l&ray Pines Road lAJoila,cA 92037.

Ceil Biology Indiana University

The Department of Biology anticipates appointing a new faculty member in cell biology, who utilizes molecular, biochemical, and genetic approaches to the study of cellular structure and function. We are particularly interested in receiving applications from individuals studying protein structure and interactions, cell-cell communications, or intracellular sorting. The successful candidate will be expected to conduct a vigorous, independent research program and contribute to teaching. Applicants should have postdoctoral research experience and demonstrated ability as creative scientists. Send curriculum vitae, a brief description of research interests, and arrange to have three letters of reference sent to: Dr. Tom Blumenthal, Chairman, Department of Bkkgy, Indiana University, Bloomington, IN 47405.

Applications received before January 1, 1990 will be assured of consideration. Indiana Uniwrsity is an At%rmatiw Action/Equal

Opportunity Employw.

Postdoctoral Fellowships at the MEDICAL BIOLOGY INSTITUTE

The Medical Biology Institute (MBI) is interested in attracting postdoctoral fellows of exceptional ability who desire an

equally exceptional opportunity for training in all aspects of immunology including the immunopathology of AIDS.

MBI is a young, vigorous basic research institute combining cellular, membrane and molecular approaches in the

investigation of medically relevant biological problems and phenomena. ll is located in La Jolla, California in the hub

of an area noted for its concentration of both academic and commercial biomedical science organizations including the

Salk Institute, Scripps Clinic and Research Foundation, the University of California at San Diego, and La Jolla Cancer

Research Foundation to name a few.

MBl’s scientific staff, having interests in Immunology, include the following:

Carol Cowing, Ph. D. - Function of class II MHC genes in immunity and tolerance; regulation of class II genes in

transgenic mice.

Ann J. Feeney, Ph. D. - Molecular and cellular analysis of idiotype dominance: generation of antibody diversity and

somatic mutation mechanisms. Daniel P. Go& Ph. D. - Molecular studies of T cell receptors involved in autoimmune disease. Identification of genes

involved in susceptibility to juvenile onset diabetes.

Chrlrtlne Gritzmacher, Ph. D. - Molecular biology of class-switch recombination and immunoglobulin gene expression in

cells.

David H. Katz, M. D. (President 81 Chief Executive Officer) - Cell/cell interactions in the immune system; the

immunobiology of the lgE system; lymphokine biology and biochemistry; mechanisms of immunological tolerance.

Alan M. Kleinfeld, Ph. D. - Lipid organization of lymphocyte membranes; free fatty acid modulation of lymphocytes;

mechanisms of free fatty acid transport.

Fu-Tong Llu, Ph. D., M. D. - Molecular biology of the IgE system including gene expression; the structure and function

of lgE and lgE-specific receptors.

John F. Marcelletti, Ph. D. - lmmunoregulation and immunoregulatory networks; isotype-specific regulation of antibody

synthesis by molecular mediators derived from Fc receptor-bearing lymphocytes, Matthew F. Mescher, Ph. D. - Molecular mechanisms of recognition, transmembrane signalling and in vivo activation of

cytolytic T lymphocytes. Structure of the lymphocyte plasma membrane.

Donald E. Mosier, M. D., Ph. D. - B lymphocyte development and interactions; AIDS animal models; human immune

function in hu-PBL-SCID mice; human B cell lymphomagenesis.

Christa Muller-Sieburg, Ph. D. - Development of the hematopoietic system; isolation of stem cells and progenitors;

regulation of differentiation by cytokines and stromal cells. Ronald T. Ogata, Ph. D. - Molecular biology of class Ill MHC products; analysis of gene structure, mechanisms

regulating gene expression, and protein structure/function relationships,

Junichl Ghara, M. D., Ph. D. - Biological, biochemical, and molecular genetic analysis of murine IL-4 receptors.

Molecular studies of IL-4 mediated T cell growth. Structure and functional relationships of murine 11-4.

Roy J. Rlblet Ill, Ph. D. -Antibody gene structure and evolution; antibody gene utilization , repertoire control, genome

structure and evolution.

David S. Ucker, Ph. D. - Programmed cell death in immunity; molecular, genetic and biochemical studies of the

mechanisms of cell suicide induced during thymic selection, and by cytotoxic T lymphocytes and by glucocorticoid

hormones. Darcy 6. Wilson, Ph. D. (Scientific Director) - lmmunobiology of T lymphocytes; idiotypic regulation in GVH and

autoimmune diseases; functional studies of T cell surface molecules.

For consideration, submit a curriculum vitae and three references to:

Carol 0. Cowing, Ph. D.

MEDICAL BIOLOGY INSTITUTE 11077 North Torrey Pines Road La dolla. California 92037 El 914503033

An Equal Opportunity/H/V Empkysc

Molecular Biologist University of Alabama

The Department of Biology, The University of Alabama is seeking applicants with research interests in the area of regulation of eukaryotic gene expression for a full time, tenure track position. The appointment can be made at any level, but special consideration will be given to full professor applicants with established publication and funding records. Generous start-up funds and space are available.

Applicants should submit their curriculum vitae, a description of research plans, and the names of three references to: Dr. John K. Hardman

Department of Biology

The University of Alabama

Box 870344 Tuscakosa, AL 35487-0344.

Review of applications will begin December 1.

The Unibwsity of Alabama is an Equal

Opportunity/AtRmatb Action Employer.

Predoctorai Interdisciplinary Program Cell Structure and Function in Health and Disease University of Florida

The University of Florida is initiating a new program providing well qualified graduate students with a broad spectrum of research opportunities in cell structure and function tailored to the specific needs of each student. Faculty interests include developmental and regulatory biology, intracellular targeting, cytoskeleton, signal transduction, immunobiology, cancer biology, and the mechanism of viral infection, The student will receive a Ph. D. degree jointly through a basic sciences department and the Interdisciplinary Program. Competitive stipends are offered by the Program.

For further information contact: Dr. Carl Feldherr Department of Anatomy and Cell Biology

College of Medklne University of Fkrlda

Gainesville, Florida 32510.

Postdoctoral Position, Ceil and Molecular Biology of Erythrocyte Membranes Johns Hopkins School of Medicine

A postdoctoral position is now available for the study of a recently identified class of erythrocyte membrane proteins related to the Fth antigens. These proteins are conserved amongst diverse species and are important tc the molecular organization of the lipid bilayer (see PNAS 85:4042-5,1988; J Dial Chem 2S3:15634-42,1%8; ibid.263:181936,1988; J Clin Invest 83:187-191, 19es). Experience in biochemistry, cell biology, or molecular biology is needed. Please send curriculum vitae, a description of research experience, and names of three references to: Dr. Peter Agre

Departments of Medicine (Hematology) & Cell

Biology/Anatomy

Bask Scknces Complex, 103 Hunterlan

Johns Hopklna School of Medicine

725 North Wolfe Street

Baltimore, MD 21205.

Assistant/Associate Professor UMDNJ-New Jersey Medical School The Department of Microbiology and Molecular Genetics at the University of Medicine and Dentistry of New jersey-New Jersey Medical School is seeking several outstanding scientists (Ph. D. or M. D.) for tenure track, assistant or associate professor positions tc be filled in 1990-1991. Successful candidates will be expected to establish a strong basic research program that is molecular in its approach and to participate in medical and Graduate School teaching. The Department has excellent facilities and is part of a large medical complex. We are particularly interested ir candidates studying either the molecular bases of microbial pathogenesls, retroviruses (especially HIV) or other viral systems. However, we encourage all qualified individuals with interests in molecular biology to apply. Send curriculum vitae, a statement of research interests, and names and addresses of three references to: Dr. Lynn S. Ripley, Faculty Search

Committee, Department of Mkrobklogy and Molecular Genetks (C), UMDNJ-New Jersey Medkal

Bchool, 155 S. Orange Avenue, Newark, NJ 07103.

UMDhU is an Equal Opporhm&hWirmatk Action

Empioyar.

Cell, Vol. 59, No. 4, November 17,1989

Doctoral Trainlng in Molecular Pharmacology SUNY at Buffalo The Department of Biochemical Pharmacology invites applications for graduate study in a multidisciplinary program in the biomedical sciences. Active areas of research include eukaryotic gene expression and molecular biology, molecular and cellular pharmacology biophysics, neurophysiology, neuropharmacology, and cancer and AlDS chemotherapy. Our program aims to train bright and motivated graduates from the sciences and mathematics to become creative and independent investigators who can successfully compete for research and teaching positions in academia and industry. The strengths of our program lie in its focus on independent study through individual scholarship, its capacity to accommodate students with diverse backgrounds and its emphasis on laboratory research al the earliest stages. Stipends carrying full waiver of tuition are available. Send requests for information and applications to: Director of Graduate Studies, 313 Hochstetter Hall, Department of Biochemical Pharmacology, SUNY at Buffalo, Buffalo, NY 14260. SUNY is an AlRmatiw Action/Equal Opportunity Employer

Assistant Professor Department of Dermatology lndlana University School of Medicine

The Department of Dermatology is seeking applications for a position of assistant professor to establish the Laboratory of Dermatopathology. Candidates should have experience in general molecular biology technique with emphasis in the regulation of prokaryotic and eukaryotic gene expression and knowledge of DNA viruses. The successful candidate will be expected to develop a strong research program and to supervise a doctoral graduate program. Applicants must have a Ph.D. with at least two years of postdoctoral experience.

Send curriculum vitae with a complete bibliography, representative reprints, description of research interests and the names and addresses of three references to: Dr. Arthur L Norlns, Department on Dermatology, Indiana Unlverslty School of Medicine, Regenstrlef Health C%nter, 1001 W. 10th Street, Indianapolis, IN 46202. Indiana Unhwsity is an Equal Opportunity/

Af?kmatiw Action Employer.

Faculty Positions The University of Western Ontario

The University of Western Ontario invites applications for two tenure track faculty positions in the Faculty of Science (one in Plant Molecular Genetics; the other in Animal Molecular Genetics). The rank will be either Assistant Professor or Associate Professor, commensurate with experience. Applications are encouraged from internationally recognized candidates with active research programs which have had a major impact in the molecular genetics of plant or animal systems. A Ph. D. and postdoctoral experience are required. The successful candidate will be expected to play a pivotal role in the expansion of molecular genetics/biology in the Faculty of Science and, to participate in a graduate program in molecular biology between the Faculties of Science and Medicine. Generous research space will be provided in a new science center currently under construction,

Applicants should submit a curriculum vitae, a one page statement of research interests, and the names of three references to:

Dr. W. S. Fyfe, Dean Faculty of Science

The University of Western Ontario London, Ontarlo

Canada N6A 587. Deadline for application is March 31, 1990.

In accordance with Canadian Immigration requirements, this advertisement is directed to Canadians citizens and permanent residents of Canada. Others are encouraged to apply. These positions are subject to budget approval.

An Equal opportunity Employar.

Cell. Vol. 59, No. 4. November 17.1989

Assistant Professor Positions Tenure Track in Neurobiology and Mammalian Cell Biology

Department of Biological Sciences Rutgers, State University of New Jersey

Individuals wishing to develop a strong research program in a department committed to excellence in research and teaching are invited to submit applications to the New Brunswick (Busch) campus of Rutgers University.

One position is in neurobiology, with a focus on the biophysical or biochemical analysis of neuronal function at he cellular and/or membrane level. The second is in mammalian cellular and molecular biology, with a focus on the regulation of gene expression and/or the control cf cell proliferation. Search ccmmittee chairs are respectively Charles Page and David Dsnhardt.

Candidates should have postdoctoral experience and a record of significant research achievements; ability to teach immunology will be an asset. Applications, with curriculum vitae and a statement of research interests, and letters from three references should be sent to the appropriate chair at:

Nelson Biological Laboratories P. 0. Box 1059

Rutgers University Piscataway, New Jersey 98855.

Rutgem University is an Equal Oppcttunily/Ati%maat Action Employer.

Research Fellow

Research Fellow who will conduct experiments in vitro with isolated and cultured cell types from the rat testis and pituitary under defined stationary and superfusion conditions. Analyze structural and functional response patterns to endocrine and paracrine manipulations by light and electron-microscopy, radioimmunoassay, bioassay, and protein purification methods. Apply appropriate evaluation methods for research data. Handle bio-hazardous material. Ph. D. Degree in Biology/Biochemistry or M. D. Degree. Two years Research Training. One year Research Experience in testis and pituitary cell morphology and biology, radioimmunoassay, microscopy, sterile techniques, protein isolation and characterization. 40 hours/week. $23,ooO annual salary. Contact: Texas Employment Commission, Houston, Texas or send resume to: Texas Employment Commission, TEC Building, Austir Texas 78778. J. 0.R 5458832. The Uniwrsity of Texas is an Equal Opportunity

Employer. Women and Minorities are encouraged tc

apply.

Molecular Biologist Emory University School of Medicine

The Wkrship Cancer Center of Emory University School of Medicine is recruiting a scientist of international reputation to develop a significant cancer-related research program. Individuals involved in transgenic studies and/or molecular analysis cf oncogenes are particularly encouraged to apply. lt is expected that the appointment will be at the rank of Associate Professor or above. Newly constructed laboratories, including a $2 million animal barrier facility, are available. Cross appointments with other University departments are enccuraged. Generous salary and start-up funds are available. Applicants should submit a curriculum vitae, statement cf research interests, and have three letters of recommendation: Kenneth W. Bell, M. D., Ph. D., Director Winship Canoer Center, Emory University School of Medicine, 1327 Clifton Road, NE, Atlanta, GA 30322. Review of applications will begin immediately and continue until the position is filled. Emory Uniwsity is an Equal Opportunify/Afr%native

Acticn Emplow.

Postdoctoral and Research Assistant Positions

Wayne Stute University

Positions available to work on molecular genetics of Neurospora. Prefer experience in molecular biology or genetics of fungal systems. Join a new lab in an expanding department. Please send a curriculum vitae and three letters of recommendation to:

Dr. Robert A. Aklnr Department of Blochemlstry Wayne State Unlversfty 540 East Canfkld Detroit, Mlchlgan 48201.

Wayne State Uniwsity is an Equal Opportunity/

Affinnatiw Action Employw.

Rutgers, New Jersey and UMDNJ-Robert Wood Johnson Medical School Announce a Shared Interdisciplinary Core Curriculum in Molecular and Cell Biology. The Graduate Programs of Rutgers University and UMDNJ-Robert Wood Johnson Medial School are seeking outstanding applicants for this interdisciplinary curriculum. Successful applicants will be awarded a fellowship providing an annual stipend of Sl2,CtGl plus tuition. Students will take a program of interdisciplinary courses, seminars, and research laboratory rotations. Research opportunities in Molecular and Cell Biology exist in all participating graduate programs of both universities, including the New Jersey Center for Advanced Biotechnology and Medicine, Waksman Institute, and Center for Agriculture Molecular Biology. Students will obtain the Ph. D. degree from the program In which they do their research project. To apply or for further information write to: Michael J. Leibowb, M.D., Ph. D., Director, Core Curriculum In Mohcukr and Cell Blokgy, Department of Molecular Genetks and Mkrobklogy, UMDNJ-Rober Wood John8on Medkal School, 675 Hoes Lane, Plsoataway, New Jersey 055545535. An Equal

Oppcrtunity/Af?i~atiw Action Employer. M/F/H/l.

Molecular Geneticists Department of Genetics University of Georgia The Department of Genetics at the University of Georgia is seeking molecular geneticists for tenure track positions available July 1990. The research areas and the academic rank are open. Individuals interested In the following areas are especially encouraged to apply: developmental genetics; nucleic acid/protein interactions; and prokaryotic molecular genetics. The successful candidates will be expected to pursue active research programs and to teach at the graduate and undergraduate level. The Department of Genetics has 15 faculty members with strong research programs in molecular and population genetics. The department will soon occupy a new stateof-the-art research facility. Applicants should arrange to have three letters of recommendation sent on their behalf. The letters, curriculum vitae, reprints of representative publications, and a statement of research interests should be mailed to: Dr. Sidney R. Kushner, Head, Department of Gene&s, University of Georgia, Athens, GA 30602. The closing date for applications is January 2,199o. The Uniwrsity of Gecgia is an Equal Opportunity/

APirmatiw9 Act& Insritution.

Cell Biology/Neurobiology Wesleyan University

A tenure track position, at the assistant professor level, is available in the Biology Department at Wesleyan University for a person who is incorporating modern structural and molecular techniques into research addressing fundamental questions in neurobiology at th cellular level. The position is made possible through a grant from the Howard Hughes Medical Institute. Applicants should have postdoctoral experience and a demonstrated ability to develop an active research program. Other responsibilities include directing the research of Ph. D. students and participating in education at the graduate and undergraduate level. Please send a curriculum vitae, a statement describing a future research program, and arrange that three letters of recommendation be sent by December 15, 1989 to: Chair, Search Commlttea for Cell Biology/ Neurobkkgy, Department of Biology, Wesleyan Univeralty, Middletown, CT 05457. Wesleyan is an Equal Oppottunity/Mknatiw Action

Emplcysr. We encourage applications from minority

candidates and women.

Cell, Vol. 59, No. 4, November 17,19&t

Graduate Study F. Edward Herbert School of Medicine in Microbiology Training Program

Molecular and Cell Biology

at

Texas A&M University Cell Fit;;;;tiation 81 Developmental

DNA-Protein Interactions Gene Expression & Control Molecular Virology & Oncology Parasitology Plant 81 Ammal Genetic Engineering Signal Transduction

Graduate research fellowships ($12,00O/year) are available for an inter-disciplinary program. Ph.D. degrees are offered in the Colleges of Agriculture 8 Life Sciences, Medicine, Science and Veterinary Medicine.

For additional information: Dr. Terry L. Thomas

Molecular & Cell Biology Program Department of Biology

Texas A&M University College Station, TX 77843

(409) 845-0184

Pre- and postdoctoral fellowships for students with

appropriate degrees in Microbiology, Biochemistry, Cell

Biology, Genetics, or related fields are funded by

training grants and research grants from NIH as well

as by intramural stipends.

Wllllam Gauee: Molecular Immunology.

john Hay: Molecular Virology.

Randall Holmes: Bacterial Toxins & Pathogenesis.

Kathryn Holmes: Virus receptors & Pathogenesis.

Frank Jenkins: Molecular Virology.

Susan bngreth: Protozoan Parasitology.

Anthony Maurelli: Bacterial Pathogenic Mechanisms.

Eleanor Metcalf: Microbial Immunology.

Alison O’Brien: Bacterial Pathogenesis.

Paul Rick: Bacterial Cell Surfaces.

Stefanio Vogel: Macrophage Differentiation.

Henry Wu: Membrane Molecular Biology.

Please send curriculum vitae and names of three

references to:

Dr. Henry C. Wu, Department of Microbiology,

Uniformed Swvlces Universlty of the Health Sciences,

Bethesda, MD 208144799.

Stanford University Announcement of a new program:

Combined Admissions Mode in Biological and Biomedical Sciences

In addition to entering a given program directly, students may now opt to enter graduate study in the biological and

biomedical sciences through Combined Admissions Mode or CAM. This new program enables a small number of select

students to begin graduate study at Stanford University without first committing to a given department or program.

During the first year, following a series of “rotations” in different departments, CAM students select a thesis adviser

and program in which to complete the Ph. 0. The flexibility and breadth offered by CAM should appeal to those who

view two or more departments as equally attractive. Participating programs are:

DEPARTMENTAL:

Biochemistry

Biological Sciences

Cell Biology

Chemistry Developmental Biology

Genetics

Microbiology and immunology

Pharmacology

Molecular and Cellular Physiology

INTERDEPARTMENTAL:

Biophysics

Cancer Biology

Immunology

Medical Information Sciences

Neuroscience8

More information and application forms for CAM can be obtained from: Office of Graduate Admissions, Building 590,

Room 208, Stanford Unlverslty, Stanford, CA 94305-3052. Deadline for receipt of completed applications is

December 15,lQQQ. Stanford University is committed to the principles of Aftirmatiw Action and welcomes applications from students of either sex and any race, color, religion, sexual orientation, or national and ethnic origin.

cell. vcl. 63, NC. 4, Noilwnber 17.1939

Director of Diagnostic Molecular Biology, NYU School of Medicine The Department of Pathology of New York University Medical School is seeking an individual responsible for the direction of a Diagnostic Molecular Laboratory. This individual is expected to be well prepared in molecular biology approaches, to have his/her own research program, and be interested in the teaching ark training of graduate students and residents. Training in Pathology is preferable. Salary and title are open, dependent upon experience and qualifications. The Department of Pathology of New York University Medical School, in addition to providing a rich source of clinical and experimental material, has a strong research component presently covering areas such as molecular oncology, tumor viruses, growth factors, regulation of cell division and differentiation, cellular molecular immunology and DNA repair. Applicants which complement the present areas of strength are particularly desirable. Applicants from minority groups ares strongly encouraged. Interested individuals shoula send a curriculum vitae to: Wttorio Defendl, Y. D.,

Department of Pathology, NYU Medlcal School of

Medicine, 660 First Avenue, Medical Science Buildlq

Room 555, New York, NY 10016.

Postdoctoral Position Department of Pathology Beth Israel Hospital and Harvard Medical School

A funded postdoctoral position is available immediately to study the molecular and cellular biology of fibronectin gene expression during wound healing. Our research is focused on elucidating the mechanisms governing alternative splicing of fibrcnectin and the biological consequences of splicing during the process of tissue repair. Applicants should have a strong background in cell biology and have an interest in molecular biology and experimental pathology.

Send curriculum vitae and the names of three references to: Dr. Lhfingston Van De Water Department of Pathology

Beth Irrml Horpital

330 Brcokline Avenue

Boston, MA 02215.

COLD SPRING HARBOR LABORATORY

PROTEIN PURIFICATION AND CHARACTERIZATION

April16-30,199O Daniel R Marshak, Cold Spring Harbor Laboratory

Bruce W. Erickson, University of North Carolina Jim Kadonaga, University of California, San Diego

John A. Smith, Harvard Medical School fhis course is intended for scientists who are not familiar with ochniques of protein isolation and characterization. Students till learn the major techniques in protein pmitlcation by actuetly performing four separate isolations including: (i) a -eg&tory protein from muscle tissue; (ii) a fusion protein from 9. coli; (iii) a DNA binding protein from nuclei of tissue culture :ells; end (iv) a chemically synthesized peptide. A variety of hromatographic, electrophomtie, and bulk fractionation ;echniques will be employed including: ion exchange, gel iltration, hydrophobic interaction, affinity-based adsorption, md immunoaffiity chromatography; polyacrylamide gel and .wo-dimensional gel electrophoresis and electroblotting; precipitation by salt and pH; and HeLC analysis. Methods of protein characterization will be discussed including amino acid molysis, protein sequenctng, and mass spectrometry. Emphasis will be placed on methods of protein purification v&her than automated instrumental analysis. Guest lecturers Kill discuss protein structure, moticetions of proteins, and nethodologies for protein purification. Applications of protein 3iochemistry to various oreas of research in molecular biology till be discussed. Guest lecturera include: R. Aebersold. 5. Donbar, D. Graves, L. Gierosch, Y. Paterson, P. Robbins, 3. Rose, and K Wilson

CLONING & ANALYSIS OF LARGE DNA MOLECULES

April 17 - 30,199o Robert Gemmill, Eleanor Roosevelt Institute, Denver

Nat Sternberg, E. I. DuPont de Nem~urs & CO. Sue Rlaphola, Stanford University

l’his course will cover the theory and practice of manipulatin Lectures an d

and cloning high molecular weight DNA. laboratory work will deal with the use of

bacteriophage Pl and yeast artificial chromosome (YAC) cloning systems, the isolation and manipulation of high molecular weight DNA from mammalian cells for cloning (including the size-selection of 200-300 kb DNA

ents), and the analysis of high molecular weight ulse field gel (PFG) ee

DNA mo ecules will be produced, P aration techniques. Pl

introduced into cells (E. coli and yeast, respectively), and relsolated after appropriate clone selection and colony screening procedures. Comparison of DNA separation capabilitres will be made among the five major PFG techniques commonly in use. All as blot analysis of DNA will be covere

ects of Southern CF

di e&ion with restriction ens m&ding sample

tie d gels, Southern transfer, ‘i r es, separation on pulse

ybridization, and interpretation of results. Students will gain hands on experience through participation in ongoing efforts to prepare physical maps of portions of human chromo- somes 3 and 12. Lectures by outside speakers on topics of current interest will supplement the laboratory work. l’uition, room and board . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $1,390

Application deadline: January 15,199O Applicationlinfonnati~~~~ined from:

‘Old s+%i?b?Tkk%$t??k3~ Cold Sprmg Phone: 61&?7-3343

Cell, Vol. 59, No. 4, November 17,1989

C. H. Best Foundation Postdoctoral Fellowship University of Toronto

In diabetes research, molecular endocrinology, molecular biology, differentiation, reproductive biology, immunology, structure and function of membranes or lipid metabolism. Tenable in the Banting and Best Department of Medical Research for two years after July 1, 1gXl with a competitive stipend available to new Ph. D.‘s or candidates with less than two years postdoctoral training by June 30,199o.

Send curriculum vitae, transcripts and three letters of reference, preferably before December 15, 1990 to:

Dr. lrvlng B. Fritz Fellowship Committee Chairman Banting and Best Department of Medical Rerearch University of Toronto Toronto, Ontario Canada M5G lL6.

Faculty Position St. Jude Children’s Research Hospital

A faculty position (degree in medicine with at least five years experience is required) is available in the Department of Immunology at St. Jude Children’s Research Hospital to work on the regulation of T lymphocyte response in experimental allergic encephalomyelitis (EAE). Candidates must have a strong background in cellular immunology and immunopathology, with extensive experience in T cell cloning and in vitro culture technique. Salary $40,000.

Send resume and references to:

Jack Hilzheim Departnrmt of Employment gecurity 1295 Poplar Avenue Memphis, TN 30104.

An Equal Ogportunity/AffimMhm Action Employer.

Two Postdoctoral Positions Molecular Biology of Human Hematopoietic Cells Harvard Medical School

Available immediately for Ph. D.‘s in molecular biology, One position to study the stem cell antigen CD34 and other human myeloid genes, defining cell type-specific promoters and using them in retroviral vectors and transgenic constructs (contact Dr. Daniel G. Tenen).

The second position to study the regulation of expression, structure, and function of major proteins of human eosinophilic and basophilic leukocytes (contact Dr. Steven J. Ackerman).

Send curriculum vitae and three letters of reference to above contacts at: Beth Israel Hospital 330 Brookline Avenue Boston, MA 02215.

Postdoctoral Position Connective Tissue Research University of Washington

Postdoctoral position is available for research in connective tissue biochemistry and the molecular biology of cartilage. Specific projects deal with: mechanisms of type II collagen gene expression, alternative splicing of collagen mRNA, growth factor effects on cartilage cells and the function and expression of proteoglycan and link proteins. Potential candidates should have a strong background in biochemistry or molecular biology.

Write stating career goals with curriculum vitae and names of three references to:

Dr. Linda J. gandell Department of Orthopaedics, RK-10 Unlveraity of Washlngton BeatBe, WA 98195.

Unkdly of Washington is an Equal Opportunity/

AtGmatiwa Action Employer.

Cell. Vol. 59. No. 4. November 17.1989

Research Assistant Position Research Assistant Position

Cancer research involving purification and characterization of nucleic acids modified by cancer chemotherapeutic drugs, DNA repair enzymes and complexes formed. Experience is required in affinity chromatography of synthetic oligonucleotides, purification of DNA-protein hybrid nolecules and radiolabeling and alhylation of DNA. Ph. D. in biology or pharmacology and at least one year

experience is required. Salary is $23,ooO.

Cancer research conducting surgical procedures in mice, ligand & binding assays, enzyme purification, gel electorphoresis, use of radioisotopes, use of human tumor zenografts, autoradiography microscopy. At least one year experience and a Ph. D. in biochemistry or pharmacology. Salary is $23,ooO.

Send resume and references to:

Jack Hilzhelm Send resume and references to:

Jack Hllzhelm

Department of Employment Security 1295 Poplar Avenue Memphis, TN 38104.

Department of Employment Security 1295 Poplar Avenue Memphis, TN 38104.

An Equal Oppettunity/iWim?atiw Action Employer.

An Equal Opportunity/Affi~atiw Action Emphyx.

ANNOUNCING... The Neuron Classified Section Neuron pubiishes classified advertisements for positions available, and for announcements of meetings, symposia, and courses. Rates are $145 for a quarter page, $270 for a half page, and $495 for a full page. We will accept either camera-ready material or copy for typesetting. When sending insertion orders, please specify if ad is to run in Neuron. Also, always include addresses for billing and proofreading purposes. Deadlines for the next available issues are as follows (all material due close of business on due date):

January 1990 issue: copy due Dec. 22,1999 February 1990 issue: copy due Jan. 19,199O

Neuron advertisements should be sent to:

MARIE ARSENAULT Neuron Classified Ad Department

Cell Press 50 Church Street

Cambridge, MA 02138 (817-881-7059) FAX Number (617-881-7061).


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