1

PORTFOLIO

VIRAL DISEASE

KHD 202

Lecture (s):

Prof. Dr, Rahaju Ernawati, Drh., M.Sc

Drh. Adi Prijo Rahardjo, M.Si

Dr. Jola Rahmahani,Drh., M.Kes

Prof. Dr. Fedik Abdul Rantam, Drh.

Prof. Dr. Suwarno, Drh., M.Si

DEPARTMENT OF MICROBIOLOGY

FACULTY OF VETERINARY MEDICINE

UNIVERSITAS AIRLANGGA

2

LIST OF CONTENTS

MODULE HANDBOOK :

A. Course Identity ........................................................................................................ 3

B. Maping LO to CO ................................................................................................... 6

C. Course topic ............................................................................................................ 6

D. Assessment Rubric .................................................................................................. 7

E. Assessment system .................................................................................................. 9

COURSE ASSESSMENT TA 2017/2018 :

A. Course Outcome Evaluation ................................................................................... 10

B. Course Development Plan ....................................................................................... 16

C. Summary of Lecturer Evaluation by Students ....................................................... 16

D. Appendix

1. Examination : Question Sheets

2. Student Answer Sample (Maximum, Average, Minimum)

3. Student Questionnaire Summary

3

MODULE HANDBOOK

Course: Viral Disease

Academic Year: 2017/2018

A. Course Identity

Module name Viral Disease

Module Level Bachelor

Abbreviation,

if applicable

KHD 202

Courses

included in

the module of

applicable

-

Semester/Ter

m

4/second year

Module

Coordinator

Prof. Dr. Rahaju Ernawati, Drh., M.Sc

Lecturer (s) Prof. Dr, Rahaju Ernawati, Drh., M.Sc

Drh. Adi Prijo Rahardjo, M.Si

Dr. Jola Rahmahani,Drh., M.Kes

Prof. Dr. Fedik Abdul Rantam, Drh.

Prof. Dr. Suwarno, Drh., M.Si

Languange Indonesia/English

Classification

s within the

curriculum

Compulsary Course

Teaching

format / class

hours per

week during

the semester

2 Hours lecture/week and 2 hours practice

Workload lecture 2 hours x 14 weeks = 28 hours

laboratory practice 2 hours x 6 weeks = 12 hours

exams 1 hour x 2 = 2 hours

FGD 1 hour x 1weeks = 1hour

quiz 1 hour x 4 = 4 hours

self study 1 hours x 14 = 14 hours

Total 64 hours

Credit points 3

Requirements Virology, Physiology, Biochemistry, and Anatomy

Learning

goals/compen

tencies

CO1 Knowing and understanding in terms of Etiology, Transmission, Pathogenesis and Clinical Symptoms of various diseases in animals

caused by DNA and RNA viruses and ways to diagnose and control the

diseases. The compulsary diseases are listed bellow:

1. Food and Mouth Disease (FMD), Stomatitis vesicularis, Malignant

4

Catarrhal Fever (MCF) 2. Canine Parvovirus, Feline Distemper, Feline Calici Virus, Corona

viruses in cats and dogs.

3. Influenza and Parainfluenza

4. Equine Encephalitis, Japanese B Encephalitis

5. Rabies, Bovine Ephimeral Fever

6. Cows’ pox, Ebola virus

7. Bovine Spongioform Encephalopaty (BSE), Scrapie, Hanta virus,

Westnile

8. Rinderpest, Bovine Virus Diarrhoea and Mucosal Disease (BVD-

MD), Jembrana

9. Bovine Leucemia, Infectious Bovine Rhinotracheitis and Infectious

Pustular Vaginitis (IBR-IPV).

10. Hog Cholera, Pseudorabies

11. Orf, Blue Tongue

CO2 Being able to applying the theories of ethiology, pathogenesis,

diagnose technique to conduct a correct conclution of viral diseases.

Make differential diagnoses and differenciate between each of them.

CO3 Being able to analyze the similar symptoms and evaluate the laboratory test (identify the viruses and serological test/ELISA, HI, CFT)

to diagnose correctly. Being able to analyze serologically and

molecularly the compulsary diseases.

CO4 After finishing the course, student would be able to conduct a teamwork to discuss some discipline lectures

1. Work discipline/complete assignments on time

2. Perseverance (effort in understanding cases which handled, effort in

improving skills)

3. Interests (focusing, responding, actively asking questions, passionate,

diligent responsibility (in performing tasks and more concerned with

duties rather than personal interests)

4. Modesty (adapting to local situations and norms, courtesy to others /

counselors)

5. Responsibility (in performing tasks and more concerned with duties

rather than personal interests)

6. Attendance

Content 1. Food and Mouth Disease (FMD), Stomatitis vesicularis, Malignant

Catarrhal Fever (MCF)

2. Canine Parvovirus, Feline Distemper, Feline Calici Virus, Corona

viruses in cats and dogs.

3. Influenza and Parainfluenza

5

4. Equine Encephalitis, Japanese B Encephalitis

5. Rabies, Bovine Ephimeral Fever

6. Cows’ pox, Ebola virus

7. Bovine Spongioform Encephalopaty (BSE), Scrapie, Hanta virus,

Westnile

8. Rinderpest, Bovine Virus Diarrhoea and Mucosal Disease (BVD-

MD), Jembrana

9. Bovine Leucemia, Infectious Bovine Rhinotracheitis and Infectious

Pustular Vaginitis (IBR-IPV).

10. Stuctural assignment/FGD

11. Hog Cholera, Pseudorabies

12. Orf, Blue Tongue

13. Structural Assignment

Study/ exam

achievement Assessment

aspect

Assessment

element

Point Course

outcome (CO)

Cognitive Assignment

Quis

Mid Exam

Final Exam

10%

10%

20%

30%

CO1, CO2,

CO3

Psychomotor Laboratory

Practice

20% CO2, CO3

Affective Focus Group

Discussion

(FGD), lecture

and laboratory

practice

Activity;

Presence;

Discipline;

Politness

10% CO4

Score Index :

A 100 ˃ AS ≥ 75

AB 70 ˃ AS ≥ 74.9

B 69.9 ˃ AS ≥ 65

BC 64.9 ˃ AS ≥ 60

C 59.9 ˃ AS ≥ 55

D 54.9 ˃ AS ≥ 45

E 45 ˃ AS

*AS = Absolute Score

Forms of

Media

Power point slide and LCD projectors, whiteboard, laboratory, ELISA

reader, Inferted microscope

Literature 1. Fenner, F. J. et al. 1995. Veterinary Virology. Terjemahan :

Putra,D.K.H. IKIP Semarang Press, Semarang

2. Murphy.F.A, EPJ Gibbs, M.C.Horzinek, M.J.Studdert. 1999.

6

Veterinary Virology 3rd Ed. Academic Press. San Diego. London. Boston. New York. Sydney. Tokyo. Toronto

3. Modrow, S., D. Falke. 1997. Molekulare Virologie. Spektrum

Akademischer Verlag. Heidelberg – Berlin - Oxford

4. Nicholas, H (2011) Fundamentals of molecular virologi

Notes -

B. Mapping LO to CO

LO CO1 CO2 CO3 CO4

LO2 Analyze diagnosis of animal diseases caused by

virus, bacteria, parasite, mold and toxin based on

physic and laboratory examination in order to

treat correctly

˅ ˅ ˅ ˅

LO8 Implement veterinary and husbandry science and

technology creatively based on ethics, morality,

religion, Pancasila and civics in public

˅

C. Course Topic

No. Week Topic

1 1 Food and Mouth Disease (FMD), Stomatitis vesicularis, Malignant

Catarrhal Fever (MCF)

2 2 Canine Parvovirus, Feline Distemper, Feline Calici Virus, Corona viruses in

cats and dogs.

3 3 Influenza and Parainfluenza

4 4 Equine Encephalitis, Japanese B Encephalitis

5 5 Rabies, Bovine Ephimeral Fever

6 6 Cows’ pox, Ebola virus

7 7 Bovine Spongioform Encephalopaty (BSE), Scrapie, Hanta virus, Westnile

8 8 Rinderpest, Bovine Virus Diarrhoea and Mucosal Disease (BVD-MD),

Jembrana

9 9 Bovine Leucemia, Infectious Bovine Rhinotracheitis and Infectious Pustular

Vaginitis (IBR-IPV).

10 10 Stuctural assignment

11 11 Hog Cholera, Pseudorabies

12 12 Orf, Blue Tongue

13 13 Structural Assignment

14 14 FGD

7

Assessment Rubic

CO Not Acceptable

0-45

Below Acceptable

45.1-64.9

Meet Acceptable

65-75

Exceed Acceptable

75.1-100

1 Students don’t know

about Etiology,

Transmission,

Pathogenesis and

Clinical Symptoms

of various diseases

in animals caused by

DNA and RNA

viruses and ways to

diagnose and control

the diseases. The

following diseases

are Food and

Mouth Disease

(FMD), Stomatitis

vesicularis,

Malignant Catarrhal

Fever (MCF),

Canine Parvovirus,

Feline Distemper,

Feline Calici Virus,

Corona viruses in

cats and dogs.

Influenza and

Parainfluenza

Equine Encephalitis,

Japanese B

Encephalitis,

Rabies, Bovine

Ephimeral Fever,

Cows’ pox, Ebola

virus, Bovine

Spongioform

Encephalopaty

(BSE), Scrapie,

Hanta virus,

Westnile,

Rinderpest, Bovine

Virus Diarrhoea and

Mucosal Disease

(BVD-MD),

Jembrana, Bovine

Leucemia, nfectious

Bovine

rhinotracheitis and

Infectious Pustular

Students have

minimal knowledge

about Etiology,

Transmission,

Pathogenesis and

Clinical Symptoms

of various diseases

in animals caused by

DNA and RNA

viruses and ways to

diagnose and control

the diseases. The

following diseases

are Food and

Mouth Disease

(FMD), Stomatitis

vesicularis,

Malignant Catarrhal

Fever (MCF),

Canine Parvovirus,

Feline Distemper,

Feline Calici Virus,

Corona viruses in

cats and dogs.

Influenza and

Parainfluenza

Equine Encephalitis,

Japanese B

Encephalitis, Rabies,

Bovine Ephimeral

Fever, Cows’ pox,

Ebola virus, Bovine

Spongioform

Encephalopaty

(BSE), Scrapie,

Hanta virus,

Westnile,

Rinderpest, Bovine

Virus Diarrhoea and

Mucosal Disease

(BVD-MD),

Jembrana, Bovine

Leucemia, nfectious

Bovine

rhinotracheitis and

Infectious Pustular

Students have more

knowledge about

Etiology,

Transmission,

Pathogenesis and

Clinical Symptoms

of various diseases

in animals caused by

DNA and RNA

viruses and ways to

diagnose and control

the diseases. The

following diseases

are Food and

Mouth Disease

(FMD), Stomatitis

vesicularis,

Malignant Catarrhal

Fever (MCF),

Canine Parvovirus,

Feline Distemper,

Feline Calici Virus,

Corona viruses in

cats and dogs.

Influenza and

Parainfluenza

Equine Encephalitis,

Japanese B

Encephalitis, Rabies,

Bovine Ephimeral

Fever, Cows’ pox,

Ebola virus, Bovine

Spongioform

Encephalopaty

(BSE), Scrapie,

Hanta virus,

Westnile,

Rinderpest, Bovine

Virus Diarrhoea and

Mucosal Disease

(BVD-MD),

Jembrana, Bovine

Leucemia, nfectious

Bovine

rhinotracheitis and

Infectious Pustular

Students have extra

ability to know the

Etiology,

Transmission,

Pathogenesis and

Clinical Symptoms

of various diseases

in animals caused by

DNA and RNA

viruses and ways to

diagnose and control

the diseases. The

following diseases

are Food and

Mouth Disease

(FMD), Stomatitis

vesicularis,

Malignant Catarrhal

Fever (MCF),

Canine Parvovirus,

Feline Distemper,

Feline Calici Virus,

Corona viruses in

cats and dogs.

Influenza and

Parainfluenza

Equine Encephalitis,

Japanese B

Encephalitis,

Rabies, Bovine

Ephimeral Fever,

Cows’ pox, Ebola

virus, Bovine

Spongioform

Encephalopaty

(BSE), Scrapie,

Hanta virus,

Westnile,

Rinderpest, Bovine

Virus Diarrhoea and

Mucosal Disease

(BVD-MD),

Jembrana, Bovine

Leucemia, nfectious

Bovine

rhinotracheitis and

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Vaginitis (IBR-IPV).Hog Cholera,

Pseudorabies, Orf,

Blue Tongue

Vaginitis (IBR-IPV).Hog Cholera,

Pseudorabies, Orf,

Blue Tongue

.

Vaginitis (IBR-IPV).Hog Cholera,

Pseudorabies, Orf,

Blue Tongue

Infectious Pustular Vaginitis (IBR-

IPV).Hog Cholera,

Pseudorabies, Orf,

Blue Tongue

2 Student do not has

ability to applying

the theories of

ethiology,

pathogenesis,

diagnose technique

to conduct a correct

conclution of viral

diseases. Make

differential

diagnoses and

differenciate

between each of

them

Student has minimal

ability to applying

the theories of

ethiology,

pathogenesis,

diagnose technique

to conduct a correct

conclution of viral

diseases. Make

differential

diagnoses and

differenciate

between each of

them

Student has the

ability to applying

the theories of

ethiology,

pathogenesis,

diagnose technique

to conduct a correct

conclution of viral

diseases. Make

differential

diagnoses and

differenciate

between each of

them

Student has extra

ability to applying

the theories of

ethiology,

pathogenesis,

diagnose technique

to conduct a correct

conclution of viral

diseases. Make

differential

diagnoses and

differenciate

between each of

them

3 Student do not has

the ability to analyze

the similar

symptoms and

evaluate the

laboratory test

(identify the viruses

and serological

test/ELISA, HI,

CFT) to diagnose

correctly. Being able

to analyze

serologically and

molecularly the

compulsary diseases

Student has minimal

ability to analyze the

similar symptoms

and evaluate the

laboratory test

(identify the viruses

and serological

test/ELISA, HI,

CFT) to diagnose

correctly. Being able

to analyze

serologically and

molecularly the

compulsary diseases

Student has ability to

analyze the similar

symptoms and

evaluate the

laboratory test

(identify the viruses

and serological

test/ELISA, HI,

CFT) to diagnose

correctly. Being able

to analyze

serologically and

molecularly the

compulsary diseases

Student has estra

ability to analyze the

similar symptoms

and evaluate the

laboratory test

(identify the viruses

and serological

test/ELISA, HI,

CFT) to diagnose

correctly. Being able

to analyze

serologically and

molecularly the

compulsary diseases

4 Student do not has

the ability to

conduct a teamwork

to discuss some

discipline lectures.

student do not has

ability to work with

discipline /complete

assignments on time

. Perseverance

(effort in

understanding cases

which handled,

effort in improving

skills).Interests.

Student has minimal

ability to conduct a

teamwork to discuss

some discipline

lectures. student has

munimal ability to

work with discipline

/complete

assignments on time

. Perseverance

(effort in

understanding cases

which handled,

effort in improving

skills).Interests.

Student has ability

to conduct a

teamwork to discuss

some discipline

lectures. student has

ability to work with

discipline /complete

assignments on time

. Perseverance

(effort in

understanding cases

which handled,

effort in improving

skills).Interests.

Modesty (adapting

Student has extra

ability to conduct a

teamwork to discuss

some discipline

lectures. student has

extra ability to work

with discipline

/complete

assignments on time

. Perseverance

(effort in

understanding cases

which handled,

effort in improving

skills).Interests.

9

Modesty (adapting to local situations

and norms, courtesy

to others /

counselors) and/or

do not has the

responsibility (in

performing tasks

and more concerned

with duties rather

than personal

interests)

or the attendance is

not fully

Modesty (adapting to local situations

and norms, courtesy

to others /

counselors) and/or

has minimal

responsibility (in

performing tasks and

more concerned with

duties rather than

personal interests)

or the attendance is

fully

to local situations and norms, courtesy

to others /

counselors) and/or

has responsibility (in

performing tasks and

more concerned with

duties rather than

personal interests)

or the attendance is

fully

Modesty (adapting to local situations

and norms, courtesy

to others /

counselors) and/or

has responsibility (in

performing tasks

and more concerned

with duties rather

than personal

interests)

or the attendance is

fully

E. Assessment System

Assessment of students including: Laboratory practice, Focus Group Discussion (FGD),

Quis, face to face test, middle examination, and final examination.

Assessment aspect Assessment element Point Course outcome

(CO)

Cognitive Assignment

Quis

Mid Exam

Final Exam

10%

10%

20%

30%

CO1, CO2, CO3

Psychomotor Laboratory

Practice

20% CO2, CO3

Affective Focus Group

Discussion (FGD),

lecture and

laboratory practice

Activity;

Presence;

Discipline;

Politness

10% CO4

The final value is defined as follow

A : 100 ˃ AS ≥ 75

AB: 70 ˃ AS ≥ 74.9

B : 69.9 ˃ AS ≥ 65

BC: 64.9 ˃ AS ≥ 60

C : 59.9 ˃ AS ≥ 55

D : 54.9 ˃ AS ≥ 45

E : 45 ˃ AS

AS= absolute score

10

COURSE ASSESSMENT YEAR 2017/2018

A. Evaluation Learning Result

CO1 Knowing and understanding in terms of Etiology, Transmission, Pathogenesis and

Clinical Symptoms of various diseases in animals caused by DNA and RNA viruses

and ways to diagnose and control the diseases (Compulsary diseases).

CO2 Being able to applying the theories of ethiology, pathogenesis, diagnose technique to

conduct a correct conclution of viral diseases. Make differential diagnoses and

differenciate between each of them.

CO3 Being able to analyze the similar symptoms and evaluate the laboratory test (identify

the viruses and serological test/ELISA, HI, CFT) to diagnose correctly. Being able to

analyze serologically and molecularly the compulsary diseases

CO4 Being able to conduct a teamwork to discuss some discipline lectures. Work with

discipline. Complete assignments on time. Perseverance (effort in understanding

cases which handled, effort in improving skills). Modesty (adapting to local

situations and norms, courtesy to others / counselors). Responsibility and Full

attendance

Course Outcome (CO) Achievement 2017:

CO1 CO2 CO3 CO4

FGD 90.00

Mid Term Examination 69.21

Final Term Examination 30.68 37.10 58.34

Laboratory Practice 65.16 65.16

Quis 80.69

Assignment 77.22 83.24

Mean 60.19 51.13 66.91 86.62

CO1 CO2 CO3 CO4

Information :

a. The mean of CO1 achievement is 60.19; it is indicate that course outcome bellow

acceptable. Students have minimal knowledge about Etiology, Transmission, Pathogenesis

and Clinical Symptoms of various diseases in animals caused by DNA and RNA viruses

and ways to diagnose and control the diseases. The following diseases are Food and

Mouth Disease (FMD), Stomatitis vesicularis, Malignant Catarrhal Fever (MCF), Canine

Parvovirus, Feline Distemper, Feline Calici Virus, Corona viruses in cats and dogs.

Influenza and Parainfluenza Equine Encephalitis, Japanese B Encephalitis, Rabies, Bovine

Ephimeral Fever, Cows’ pox, Ebola virus, Bovine Spongioform Encephalopaty (BSE),

Scrapie, Hanta virus, Westnile, Rinderpest, Bovine Virus Diarrhoea and Mucosal Disease

(BVD-MD), Jembrana, Bovine Leucemia, nfectious Bovine rhinotracheitis and Infectious

Pustular Vaginitis (IBR-IPV).Hog Cholera, Pseudorabies, Orf, Blue Tongue.

b. The mean of CO2 achievement is 51.13; it is indicate that course outcome bellow

acceptable. Student has minimal ability to applying the theories of ethiology,

pathogenesis, diagnose technique to conduct a correct conclution of viral diseases. Make

differential diagnoses and differenciate between each of them

11

c. The mean of CO3 achievement is 66.91; it is indicate that course outcome meet

acceptable. Student has ability to analyze the similar symptoms and evaluate the

laboratory test (identify the viruses and serological test/ELISA, HI, CFT) to diagnose

correctly. Being able to analyze serologically and molecularly the compulsary diseases.

d. The mean of CO4 achievement is 82.52; indicated that course outcome exceed acceptable.

Student has extra ability to conduct a teamwork to discuss some discipline lectures.

student has extra ability to work with discipline /complete assignments on time,

perseverance (effort in understanding cases which handled, effort in improving skills).

Interests. Modesty (adapting to local situations and norms, courtesy to others / counselors)

and/or has responsibility (in performing tasks and more concerned with duties rather than

personal interests) and their attendance is fully.

.

Course Outcome (CO) Achievement 2018:

CO1 CO2 CO3 CO4

FGD 90.00

Mid Term Examination 70.57

Final Term Examination 48.45 62.75 57.79

Laboratory Practice 72.27 72.27

Quis 71.29

Assignment 76.69 85.5

Mean 63.44 67.51 68.92 87.75

CO1 CO2 CO3 CO4

Information :

a. The mean of CO1 achievement is 63.44; it is indicate that course outcome bellow

acceptable. Students have minimal knowledge about Etiology, Transmission,

Pathogenesis and Clinical Symptoms of various diseases in animals caused by DNA and

RNA viruses and ways to diagnose and control the diseases. The following diseases are

Food and Mouth Disease (FMD), Stomatitis vesicularis, Malignant Catarrhal Fever

(MCF), Canine Parvovirus, Feline Distemper, Feline Calici Virus, Corona viruses in cats

and dogs. Influenza and Parainfluenza Equine Encephalitis, Japanese B Encephalitis,

Rabies, Bovine Ephimeral Fever, Cows’ pox, Ebola virus, Bovine Spongioform

Encephalopaty (BSE), Scrapie, Hanta virus, Westnile, Rinderpest, Bovine Virus

Diarrhoea and Mucosal Disease (BVD-MD), Jembrana, Bovine Leucemia, nfectious

Bovine rhinotracheitis and Infectious Pustular Vaginitis (IBR-IPV).Hog Cholera,

Pseudorabies, Orf, Blue Tongue.

b. The mean of CO2 achievement is 67.51; it is indicate that course outcome meet

acceptable. Student has the ability to applying the theories of ethiology, pathogenesis,

diagnose technique to conduct a correct conclution of viral diseases. Make differential

diagnoses and differenciate between each of them

c. The mean of CO3 achievement is 68.92; it is indicate that course outcome meet

acceptable. Student has ability to analyze the similar symptoms and evaluate the

laboratory test (identify the viruses and serological test/ELISA, HI, CFT) to diagnose

correctly. Being able to analyze serologically and molecularly the compulsary diseases.

12

d. The mean of CO4 achievement is 87.75; indicated that course outcome exceed

acceptable. Student has extra ability to conduct a teamwork to discuss some discipline

lectures. student has extra ability to work with discipline /complete assignments on time,

perseverance (effort in understanding cases which handled, effort in improving skills).

Interests. Modesty (adapting to local situations and norms, courtesy to others /

counselors) and/or has responsibility (in performing tasks and more concerned with

duties rather than personal interests) and their attendance is fully.

The Graphic of CO assessment at the academic year 2017 and 2018

0

10

20

30

40

50

60

70

80

90

100

CO1 CO2 CO3 CO4

2017

2018

Information : The graphic above shows that there is a slightly increase of every CO from

2017 to 2018, although based on statistical analytic it is not significantly

different.

13

Course Outcome (CO) mapping to Learning Outcome (LO) Achievement

201:

CO1 CO2 CO3 CO4 Average

of LOG

LO 2: Analyze diagnosis of animal

diseases caused by virus, bacteria,

parasite, mold & toxin based on

physic and laboratory examination

in order to treat correctly.

60.19

51.13

66.91

59.41

LO 8: Implement veterinary and

husbandry science and technology

creatively based on ethics,

morality, religion, Pancasila and

civics in public

86.62

86.62

Course Outcome (CO) mapping to Learning Outcome (LO) Achievement 2018:

CO1 CO2 CO3 CO4 Average

of LOG

LO 2: Analyze diagnosis of animal

diseases caused by virus, bacteria,

parasite, mold & toxin based on

physic and laboratory examination

in order to treat correctly.

63.44

67.51

68.92

66.62

LO 8: Implement veterinary and

husbandry science and technology

creatively based on ethics,

morality, religion, Pancasila and

civics in public

87.75

87.75

14

Lecture evaluation by students (EDoM) 2017:

No. Question Respondents Score

(1-4)

Index Satisfaction

(%)

1 Lecturer delivering course contracts

at the beginning of lecture

290 3.39 84.75

2 Lecturers had start and end lectures

on time according to the specified

schedule

290 3.20 80.00

3 Lecturers provide constructive

feedback on student learning

outcomes (assignments,

examinations, quizzes, etc.)

290 3.38 84.50

4 Lecturers use the latest reference

books and literature (last 5 years)

290 3.42 85.5

5 Lecturers conformity between the

material presented with the planning

in the lecture contract

290 3.43 85.75

6 Lecturers carry out the test questions

and details of the assignments

290 3.47 86.75

7 Lecturers carry out course with

teaching materials / dictates /

handouts

290 3.39 84.75

8 Lecturers use material course along

with examples of application or real

illustrations related to material course

290 3.40 85.00

9 Lecturers use of various learning

media (whiteboards, properties,

OHPs, LCDs, projectors, films, etc.)

290 3.40 85.00

10 Lecturers ability in integrating of

various learning media

290 3.41 85.25

11 Lecturers show attention to students

(eg, provide opportunities to ask

questions, respond to questions /

comments)

290 3.34 83.5

12 Lecturers use implement teaching

methods that can enhance interaction

between students and students with

lecturers

290 3.27 81.75

Mean

15

Lecture evaluation by students (EDoM) 2018:

No. Question Respondents Score

(1-4)

Index Satisfaction

(%)

1 Lecturer delivering course contracts

at the beginning of lecture

269 3.55 88.75

2 Lecturers had start and end lectures

on time according to the specified

schedule

269 3.32 83.00

3 Lecturers provide constructive

feedback on student learning

outcomes (assignments,

examinations, quizzes, etc.)

269 3.50 87.50

4 Lecturers use the latest reference

books and literature (last 5 years)

269 3.49 87.25

5 Lecturers conformity between the

material presented with the planning

in the lecture contract

269 3.50 87.5

6 Lecturers carry out the test questions

and details of the assignments

269 3.51 87.75

7 Lecturers carry out course with

teaching materials / dictates /

handouts

269 3.48 87.00

8 Lecturers use material course along

with examples of application or real

illustrations related to material course

269 3.45 86.25

9 Lecturers use of various learning

media (whiteboards, properties,

OHPs, LCDs, projectors, films, etc.)

269 3.46 86.5

10 Lecturers ability in integrating of

various learning media

269 3.49 87.25

11 Lecturers show attention to students

(eg, provide opportunities to ask

questions, respond to questions /

comments)

269 3.39 84.75

12 Lecturers use implement teaching

methods that can enhance interaction

between students and students with

lecturers

269 3.36 84.00

Mean 3.46 86.5

16

Summary of Lecture Evaluation by Students AY 2017/2018

From the data of satisfaction index by students in order to evaluate the lectures performance,

We make 12 indicators of satisfaction index that can be seen at table of lecture evaluation by

students. The data is summerize in the graphic bellow. The graphic shows that there are

slightly increase in indicator 4, 5, 6, 8, 9, and 11. Increase dramatically in indicator 1, 2, 3,

and 12.

DEBELOPMENT PLAN

To achieve a good goal in the next academic year of viral diseases’ course we will :

1. Innovate the learning method so that the students more active in class, FGD, and face

to face.

2. Looking for students who have a good quality to be lecture assistance to help the

younger student to understand more about viral diseases.

3. Give more time for the student to do face to face

17

MIDDLE SEMESTER EXAM INFECTIOUS DISEASE II (I.P VIRAL)

SEMESTER : IV

DAY / DATE :THURSDAY APRIL 20, 2017

TIME : 50 MINUTES

I. For each of the following multiple choice questions, choose the one most

appropriate answer:

1. Pathogenesis of the following disease involving antibody-dependent enhancement of

infection

A. Feline Infectious Peritonitis D. Feline Panleukopenia

B. Feline calici vinrs E. Coronavirus Canine Diarrhea

C. Feline Rhinotracheitis

2. Serologicaaly Canine Coronavirus Diarrhea is related to:

A. Canine Distemper D. Transmissible gastroenteritis

B. Canine Parvovirus E. Feline Rhinotracheitis

C. Feline Peritonitis lnfectious

3. Prevention of canine parvovirus in dogs can use a vaccine containing a virus:

A. Diarrhea Canine Coronavirus D. Feline Caliciviiuses

B. Canine Parainiluenza E. Feline parvovirus

C. Transinissible gastroenteritis

4. “Kennel Cough Syndrome" is often associated with virus infection :

A. Canine Distemper C. Paraintluenza Virus 1 E. Parainfluenza Virus 3

B. Canine Paiyovirus D. Parainfluenza Virus 2

5. “Shipping Fever" in cattle is often associated with viral infection ;

A. Influenza A C. Parainfluenza Virus l E. Parainfluenza Virus 3

B. Influenza B D. Paraintluenza Virus 2

6. The following symptoms may be observed in horses infected with influenza virus A,

except:

A. Conjunctivitas D. Red nose mucous

B. Increased body temperature E. Diarrhea

C. Cough

7. Effective serologic test for detection of maternal antibodies to parvovirus in puppies

A. HA B. HI C. CFT D. AGPT E. FAT

8. Ebola virus can infect animal with exception;

A. Gorillas B. Chimpanzees C. Antelop D. sheep E. Monkey

9. The specific binding receptor of ebola virus is;

A. Nucleo protein B. Viral protein C. Glicoprotein D. viral protein30 (VP30)

E. Viral protein 40

10. Characteristic of rabies street strain virus are:

A. Highly virulent B. Cause Rabies in dogs

C. Highly variable of incubation period D. invade the salivary gland

E. All answer are true

11. Which of the following synonyms is not for rabies:

A. Hydrophobia B. Lyssa C. Penyakit anjing gila

D. Pseudorabies E. Tollwut

12. Clinical stadium of rabies as follows:

A. Convulsion B. Paralitic C. Furious

D. Prodromal E. All answer are true

13. Rabies caused by:

18

A. poxvirus B. Orthomyxo Virus C. Reovirus

D. Lyssavirus E. Coronavirus

14. Virological diagnosis of Equine Encephalitis can be done by:

A. virus Neutralization

B. HA test

C. Isolation of virus in the brains of mice and identification with the FAT

D. Polymerase Chain Polymerase (PCR)

E. nucleotide sequencing

15. The sensitivity of serological tests in the diagnosis of Equine Encephalitis are:

A. CFT> Test SN > HI Test

B. SN test> CFT.> HI test

C. HI Test> Test SN> CFT

D. HA Test> Test HI

E. PCR> Sequencing of nucleotides

16. Equine Encephalitis caused by a virus ;

A.The genus Alphavirus, Family Flaviviridae

B. Alphavirus genus, Togaviridae Family

C. Genus Flavivirus, Flaviviridae Family

D. Genus Flavivirus, Togaviridae Family

E. Genus Flavivirus, Family Adenoviridae

17. Host amplifier in the Japanese encephalitis is:

A. Horse B. Human C. Fowl D. Pig E. Bat

18. MCF is characterized by the following properties, except;

A. Caused by bovine herpes virus -3

B. Necrosis and lesions on the oral mucosa

C. Keratoconjunctivitis

D. Encephalitis

E. Blisters on the feet

19. An anthropod vector may be involved in its transmission of this disease :

A. MCF B. Foot and Mouth Disease C. Stomatitis Vesicularis

D. Exsanthema Vesicularis E. Pestis Suum

20. Leucopenia in blood tests can be found in an infected dog:

A. Diarrhea Canine Coronavirus D. Canine Parainfluenza

B. Canine Distemper E. Rabies

C. Canine Parvovirus

II. Answer the following questions by using the key below:

A. if 1,2,3 are correct

B. if 1 and 3 are correct D. if only 4 is correct

C. if 2 and 4 are correct E. if all are correct

21. The strategies of ebola virus infection by animal are

1. Binding attachment factor by receptor to pre membrane cell,

2. GP cleavage protein by cysteine proteases,

3. NPC1 binding with GP1alfa,

19

4. Building viral nucleocapsid

22. Molecule substances, that can mediated of antibody dependent enhancement are;

1. Fc-receptors 2. Integrand 3. C1q-ligands 4. Interferon-gama

23. Ebola virus can infect many cell types including ;

1. monocytes 2. Macrophages 3. dendritic cells, 4. endothelial cells

24. Animals which suffer from Rabies:

1. Cat 2. Horse 3. Goat 4. Chicken

25. Animals that can act as reservoir of Rabies:

1. Wolf 2. Horse 3. Bat 4. Cow

26. Which of the following diseases is/are zoonotic:

1. Rabies 2. Malignant Catarrhal Fever

3. Food and Mouth Disease 4. Feline Distemper

27. Incubation period of Rabies depend on:

1. dose of virus

2. distance from the bite wound to the CNS

3. severity of the bite wounds

4. number of sensory nerves ending

28. Properties of the Equine Encephalitis:

l. Is a zoonotic disease

2, Can be caused by a strain enzootic and epizootic

3. Causative virus has antigenic relationship with Chikungunya virus

4. Many are found in Indonesia

29. Japanese encephalitis virus has antigenic relationship with viruses:

l. West Nile 2. St. Louis 3. Murray Valley 4. Equine enterovirus

30. VEE virus :

l. is viscerotropic 3. Not always lead to encephalitis

2. are neurotrophic 4. Always lead to encephalitis

31. Clinical symptoms of Japanese encephalitis include;

1. Mummified fetuses in pigs 3. Decreased mobility of sperm in male

pigs

2. Long-term neurological disability in children 4. Skin blisters in horses

32. To prevent FMD typeA should be used FMD vaccine:

1.Type O 2. Type C 3. SAT-1 type 4. type A

33. These diseases cause symptoms of diarrhea and erosion of the lining of the oral cavity

l. FMD 2. MCf 3.SV 4. BVD-MD

34. The following disease is transmitted through mosquito bites

l. BVD 2. Vaksinia 3. FMD 4. SV

35. Similarities between the FMD and MCF is/are :

1. The existence of the mouth vesicle 3. Corneal opacities, and neurological symptoms

2. Lesions on the feet 4. Erosion of the mouth mucosa

36. The following is a statement about MCF:

1. Sheep and cattle are sensitive 3. low morbidity

2. Often CNS disorders 4. keratoconjunctivitis

37. The following animals are sensitive to FMD :

1. Cow 2. Pigs 3. Sheep 4. horse

38. The following animals are sensitive to SV :

1. Cow 2. Pigs 3. Sheep 4. horse

39. Serotype of SV disease is describe below

20

l. Indiana Type 2. Type Mass 3. New Type Yersey 4. type Asia

40.Feline Calicivirus Disease:

l. Gastrointestinal disease in cats 3. Cause severe diarrhea in kittens

2. Transmission by aerosol 4. Cats can still be recovered as a career

41. The following symptoms can be found in the infected cat with Caliciviruses:

l. Conjunctivitas 2. Rhinitis 3. Epithel ulcerated mouth 4. severe diarrhea

42. Differential diagnosis of Feline Caliciviruses Disease:

l. Feline Panleukopenia 3. Feline parvovirus

2. Feline Infectious Peritonitis 4. Feline Rhinotracheitis

43. The name of genera ebola virus are;

1. Zaire 2. Sudan 3. Reston 4. Bundibugyo

44. Epizootic cycle caused by ebola virus appear sporadically producing high mortality;

1. Non human primates 2. Precede human outbreaks 3. Acute disease

4. Transmission human to human

III. ANSWER the following questions by using the key below:

A. if both statement and reason are true and related cause and effect

B. if both statement and reason are true but not related cause and effect

C. if the statement is true but the reason is false

D. if the statement is false but the reason is true

E. if both statement and reason are false

45. Differential diagnosis of FMD is Stomatitis Vesicularis because SV and FMD caused by

the viruses of the same genus.

46. Ebola virus disease (formerly called Ebola Hemorrhagic disease) is a severe, often fatal,

disease in humans and non-human primates because ebola viruses have the ability to

turn internal organs into a soup that promptly flows out of the body.

47. The incubation period of Rabies are 14 days, because the migration time of the Rabies

virus to reach the central nervous system are fixed.

48. Rabies Fixed virus strain cannot be detect in the dog’s saliva, because the Rabies Fixed

virus strain migrate to the central nervous system by neurons.

49. Epizootic strains caused Equine Encephalitis more harm than Enzootic strain, because

The strain of enzootic of Epizootic Equine Encephalitis is a virus strain that has been

experienced in the natural attenuation.

50. Stomatitis vesikularis called Pseudo FMD CAUSE stomatitis vesikularis have clinical

symptoms similar aphthae Epizootika

21

Final Semester Exam Infectious Viral Disease II (I.P. VIRAL) Faculty of Veterinary Medicine – Airlangga University Semester : IV Day/date : Thursday, 06 th July 2017 Time : 80 minutes_______________________________________________________ I. CHOOSE ONE OF THE MOST CORRECT ANSWER 1. To prevent puppies against canine distemper it may be possible by using vaccines virus of; A. Parvovirus B. HPD C. Hepatitis Contagiousa Canis

D. Rinderpest E. Feline panleukopenia 2. Canine distemper is caused by; A. Paramyxovirus B. Orthomyxovirus C. Pseudomyxovirus D. Adenovirus E. Parvovirus 3. Transmission of smallpox disease in pigs (pigpox) the most dominant over by the vector namely: A. Mosquito B. Flies C. Tick D. Ectoparasites E. Culex 4. Clinical symptoms ORF in affected sheep are described below, except: A. Crusting skin B. Lesions in the mouth C. Lesions in the nasal D. Lesions on Vulva E. Lesions on the ear 5. The following property is not about Jembrana disease: A. Host affected is Bali cattle B. Caused by lentivirus C. There are enlargement and swelling of limphnode and spleen D. There are clinical symptoms hypersalivation and haemorrhagic diarrhea E. Transmitted by mosquito vector 6. The following statement is character of Malignant catarrhal fever , except :: A. Caused by Rhabdovirus B. There was an erosion lesions in the oral mucous membrane and interdigital space C. The causative virus has antigenic relationship with pestis suum D. Encephalitis is one of the clinical symptoms E. Causative virus can be inoculated in embryonated egg 7. The following statement is character of BVD-MD, except: A. Caused by Arbotogavirus B. Can be adapted on pig kidney cell C. Certain serotype can be aglutinate erythrocytes D. Can be cultivated in embryonated egg E. There is antigenic relationship with pestis suum 8. Leucopenia in blood examination was found in; A. Rinderpest D. Jembrana B. MCF E. FMD C. BVD-MD 9. The spread of west nile virus in animals is through vectors: A.Culex sp D. Anopheles sp

22

B. Aides Aegypty E. Stomoxys Calsitrans C. Aides Albopicus

10. The laboratory diagnosis of west nile virus infected animal is the following methods: A. PCR B. ELISA C. CFT D. AGPT E. HA-HI 11. This viral infections play a role within "Kennel Cough Syndrome" in dog: A. Parainfluenza virus 1 B. Parainfluenza virus 2 C. Parainfluenza virus 3 D. Influenza A E. Influenza B

12. "Shipping Fever" is often associated with : A. Parainfluenza virus 1 B. Parainfluenza virus 2 C. Parainfluenza virus 3 D. Sendai virus E. Simian virus 5

13. Bacterial infection that often as a secondary infection in Canine Distemper : A. Salmonella B. Pasteurella C. Mycoplasma D. Ecoli E. Bordetella bronchoseptica

14. The following symptoms appear in infected horse with Influenza A , except: A. Conjunctivitis B.Increasing of body temperature C. Coughing D. Red nose mucous E. Diarrhea

15. Protein that has important function when hantavirus infects a cell is :

A. Polymerase protein B. Lipid protein

C. Nucleocapsid protein. D. Glycoprotein E. Matrix protein

16. Sources of west nile disease virus in animals is the following: A. Mouse B. Horse C. Cow D. Deer E.Bird 17. Examination materials for the purpose of isolation virus from infected pigs suspected

Influenza is; A. Cloacal swabs B. Nasal mucus C. Blood D. Serum E. Faeces

18.Japanese encephalitis caused by: A. Alphavirus B. Flavivirus C. Herpesvirus D. Retrovirus E. Enterovirus 19.Characteristic of Enzootic Bovine leukosis is described bellow, except: A. Occurred in all sex and breed cows (beef and dairy) B. Common in dairy cattle than beef cattle C. Contagious for human D. Affected lymphoreticular system E. Disease characterized by persistent and malignant 20. Enzootic Bovine leukosis is caused by: A. Herpesvirus B. Coronavirus C. Rhabdovirus D. Enterovirus E. Retrovirus 21. Which of the symptoms are not for Aujeszky’s Disease A. Urticaria B. Paralyse of the pharynx C. pigs are the main host D. haemorrhagic diarrhea E. Affect animal become furious

22. The synonym of Pseudorabies is: A. Hog Cholera B. Lyssa C. Pseudoaphtae D. Pestis suum E. Aujeszky’s Disease 23. Transmision of Ebola disease is through:

A. Food C. Through drinks

23

B. Secretion which contain Ebola virus D. Aerosol short distance E. Direct contact

24. The Ebola virus infects the cell via a specific protein that is A. Glycoprotein C. Matrix protein B. Nucleocapsid protein D. Ribonucleic protein E. Fusion proteins

25. Prevention of hantavirus disease can be done by means of vaccination with this type of vaccine, except A. Inacactivated vaccine C. DNA vaccines B. Recombinant vaccines with E coli D. Rodent brain derived E. Active vaccine

26. Which of the following Differential Diagnosis of Hog Cholera is false: A. Erysipelas B. Pseudorabies C. Foot and Mouth Disease D. Pasteurellosis E. Teschen Disease 27. Which of the folloving symptoms of Hog Cholera is false: A. Encephalitis B. Pneumonia C. Button ulcer on the colon mucosa D. Diarrhoea E. hemorrhages of serous membranes and subcutan 28. BEF can be diagnosed with these methode, except: A. SNT B. CFT C. FAT D. HA and HI-test E. Virus isolation and Identifikation

II. Answer the following questions by using the key below:

A. if only 1,2,3 are correct

B. if only I and 3 are correct D. if only 4 is correct

C. if only 2 and 4 are correct E. if all are correct 29. The most susceptible animal to Srapie is: 1. Cow 2. Goat 3. Buffalo 4. Sheep 30. The following disease is transmitted through mosquito bites: 1. BVD-MD 3. FMD 2. Rinderpest 4. Stomatitis vesikularis 31. The pathological changes caused by BVD-MD are: 1. Lymphoid tissue damage 3. Erosion and ulsera of the digestive tract 2. Balamitis 4. Encephalitis 32. Clinical manifestations of hantavirus infection in animal : 1. Hemorrhagic fever with renal syndrome 2. Nephropatia 3.pulmonary syndrome 4. Paralysa

33. Inoculation of this virus on the footpad cavia cause vesicula: 1. MCF 2. Stomatitis vesicularis 3. Rinderpest 4. FMD

34. Pathological changes caused by FMD virus : 1. Lymphoid tissue damage 3. Erosion and ulsera of the digestive tract 2. Encephalitis 4. Heart degeneration

24

35. The following clinical symptoms seen in dog suffering of HCC: 1. Tonsils red and swollen 2.Abdomen pain 3. Edema in the head, abdomen and neck 4. Fever bifasis

36. Synonyms of distemper dogs are: 1. Maladie de care 2. Rubarth 3. Febrile catarrhalis infectiousa canis 4. Encephalitis wolf

37.Characteristic of HCC in dogs are describe bellow: 1. Presence of intranuclear inclusion bodies 2. Rapid course of the disease

3. Corneal opacity in one eye 4. Corneal opacity in both eyes 38. Animals are the most susceptible to Scrapie is:

1. Cow 2 goats 3. Buffalo 4. Sheep 39. This below which includes the properties of prions are: 1. Smaller than the virus 2. Not been characterized by complete 3. Infectious protein particles 4. Unstable 40. Accurate method that can be used to detect BSE is: 1.Immunohistochemistry 2. Western blotting 3. ELISA 4. CFT 41. This below that the general properties of the poxvirus are: 1. Survive for years in dust 2. Containing more than 30 different structural proteins 3. Replication intracytoplasmic 4. Not durable in dust 42. Blue Tongue disease transmission in goats mostly through below: 1. Culex mosquitoes 2. Mechanic 3 Ticks. 4. Lice 43. Specific clinical symptoms of blue tongue in infected animal is: 1. ulceration and lesions in the mouth 2 swollen tongue and cyanotic 3. Feet coronitis 4 feet lameness 44. Differences protein between influenza A virus and influenza B virus: 1.Protein M1 2. Protein H 3.Protein NP 4. Protein N 45. Protein involve in determination of Influenza A virus subtype: . 1. Protein M1 2. Protein H 3.Protein NP 4.Protein N 46. This serological test can be used to measure maternal antibody titre against parvovirus in dogs: 1. AGPT 2. HA test 3. FAT 4. HI test 47. The following symptoms appear in parvovirus infected puppies: 1. Vomiting 2. Corneal opacity 3. Diarrhea profus 4. Tic Convulsion 48. Venezuelan Equine Encephalitis has the following properties 1. High mortality 2. No death 3. Neurotrophic 4. Viscerotropic 49. Disease can be confused with Equine Encephalitis is: 1.Tetanus 2. Rabies 3. Botulismus 4. Japanese Encephalitis 50. Eastern Equine Encephalitis vectors are describe below : 1. Aedes 2. Mansonia 3. Culex 4. Culiseta melanura 51. Important variant of Equine Encephalitis virus which cause epizootic in America: 1. Subtype IA 2. Subtype IB 3 Subtype IC 4. Subtype II (Everglades) 52. Genital form of Infectious Pustular Vulvovaginitas accomplished by using the following . statement, except: 1. Ecephalitis 2. Genital mucous hyperemia with 1-2 mm vesicle

25

3. Red nose 4. Balanophostitis

53. Differential diagnosis of Infectious Bovine Rhinotracheitis are: 1. Enzootic bronchopneumonia 2. Bovine Viral Diarrhea (BVD) / mucosal disease (MD) 3. Gangrenous coryza 4. Rinderpest

54. Enzootic bovine leukosis is transmitted through: 1 Horizontal Transmission 2. Infected blood. 3. Vertical transmission 4. Insect bite

55. Characteristic of ebola disease in monkeys are marked by; 1. Bleeding 3. Abnormal blood coagulation 2 Paralysis 4. Profuse diarrhoe

56. Clinical symptoms in dogs and cats infected with west nile virus is ; 1. Fever, depression 3. Paralysis 2. Muscle weakness 4. Myocarditis

57. Desinfectant against contaminants pox virus that are either: 1. Sodium hipochloride 3. Detergent 2. Phenol 2% 4. Formalin 1%

58. Which of the following diseases is zoonotic: 1. Rabies 2. Pseudorabies 3. Food and Mouth Disease 4. Hog Cholera 59. Organs where Hog Cholera virus can be found are: 1. lymphnode of the respiratoric tract 2. leucocyte 3. intestine mucosa 4. Brain 60. To prevent Hog Cholera, piglets can be given: 1. Live vaccine 2. Killed vaccine 3. Combination of Antisera and live vaccine 4. Combination of Antisera and killed vaccine 61. Statement about Hog Cholera virus are are true: 1. Hog Cholera virus consist only one strain/serotype 2. can be ready inactivated by lipid solvent 3. cross reacted with Mucosal Disease virus 4. can be cultivated in chicken embrionated eggs by allantoic sac route 62. Characteristic for Bovine Ephemeral Fever are:

1. Transmitted by mosquitos 2. Morbidity rate great as 80% 3. Only cow and buffalo are affected 4. Can be transmitted by direct contact

63. Synonym of BEF is/are: 1. Three day sicknes 2. Bovine epizootic fever 3. Stiff sicknes 4. Bovine catarrhal fever

64. These animals can act as reservoir in Rabies: 1. Wolves 2. Horses 3. Vampire 4. Cows 65. The symptoms of Rabies which is often overlooked:

1. Paralytic 2. Prodromal

26

3. Excitability 4. Behavior changes

III. ANSWER the following questions by using the key below: A. if both statement and reason are true and related cause and effect B. if both statement and reason are true but not related cause and effect C. if the statement is true but the reason is false D. if the statement is false but the reason is true E. if both statement and reason are false

66. Clinical symptoms of hantavirus infection is haemorrhagic fever accompanied by renal

syndrome BECAUSE hantavirus also cause pulmonary syndrome

67. During the incubation period of rabies virus infection, antibody responses were undetected, BECAUSE rabies virus spread to the CNS via nerve fibers.

68. Hantavirus if infects the cells do not cause cytopathic effect because hantavirus has persisten when infecting cells derived from mice (rodent)

69. Bovine Enzootic bovine leukosis common in mature cow, especially those in the culling,

BECAUSE Enzootic bovine leukosis not contagious for humans.

70. The first replication virus if infected with the smallpox virus in squamous epithelium, BECAUSE smallpox virus viremia occurred after multiple infections in the skin epidermis.

71. Cow pox can attack humans with clinical symptoms of pocks on hand BECAUSE, cow pox also attack cat with crater clinical symptoms like ulcers

72. Orf is a disease in sheep known as scabby mouth BECAUSE, ORF causes lesions on the lips of sheep and crusta

73. Renderpest disease is a differential diagnosis of Jembrana disease BECAUSE, renderpest disease and Jembrana diseases caused by viruses of the same group.

74. Blue tongue is a disease of ruminants as hospes primer is the goat, BECAUSE Blue tongue is an contagious disease of cattle, sheep and deer.

75. Eastern Equine Encephalitis virus is a member of the genus flavivirus BECAUSE, Japanese encephalitis virus is a member of the family Flaviviridae

76. Ebola disease known as haemorrhagic fever disease because ebola disease in addition to attack the hepatocytes cells also attack the endothelial cells

77 The Morbidity rate of BEF is low, BECAUSE BEF is transmited by mosquitos.

27

78. Pseudorabies is also known as Mad Itch Disease, BECAUSE generally pigs infected with Pseudorabies shown CNS disorder.

79. Hantavirus can be secreted through excreta aerosol mice because hantavirus can be

horizontal transmited in mice 80. Hypersalivation can be seen in Dogs infected with Rabies virus, BECAUSE the replication

of Rabies virus take place in salivary gland

================== || ================

28

MIDDLE SEMESTER EXAM INFECTIOUS DISEASE II (I.P VIRAL)

SEMESTER : IV

DAY / DATE :THURSDAY MARCH 29, 2018

TIME : 50 MINUTES

I. For each of the following multiple choice questions, choose the one most

appropriate answer:

1. Characteristic of rabies street strain virus are:

A. Highly virulent B. Cause Rabies in dogs

C. Highly variable of incubation period D. invade the salivary gland

E. All answer are true

2. Which of the following synonyms is not for rabies:

A. Hydrophobia B. Lyssa C. Penyakit anjing gila

D. Pseudorabies E. Tollwut

3. Clinical stadium of rabies as follows:

A. Convulsion B. Paralitic C. Furious

D. Prodromal E. All answer are true

4. Rabies caused by:

A. poxvirus B. Orthomyxo Virus C. Reovirus

D. Lyssavirus E. Coronavirus

5. Pathogenesis of the following disease involving antibody-dependent enhancement of

infection

A. Feline Infectious Peritonitis D. Feline Panleukopenia

B. Feline calici vinrs E. Coronavirus Canine Diarrhea

C. Feline Rhinotracheitis

6. Serologicaaly Canine Coronavirus Diarrhea is related to:

A. Canine Distemper D. Transmissible gastroenteritis

B. Canine Parvovirus E. Feline Rhinotracheitis

C. Feline Peritonitis lnfectious

7. Prevention of canine parvovirus in dogs can use a vaccine containing a virus:

A. Diarrhea Canine Coronavirus D. Feline Caliciviiuses

B. Canine Parainiluenza E. Feline parvovirus

C. Transinissible gastroenteritis

8. “Kennel Cough Syndrome" is often associated with virus infection :

A. Canine Distemper C. Paraintluenza Virus 1 E. Parainfluenza Virus 3

B. Canine Paiyovirus D. Parainfluenza Virus 2

9. “Shipping Fever" in cattle is often associated with viral infection ;

A. Influenza A C. Parainfluenza Virus l E. Parainfluenza Virus 3

B. Influenza B D. Paraintluenza Virus 2

10. The following symptoms may be observed in horses infected with influenza virus A,

except:

A. Conjunctivitas D. Red nose mucous

B. Increased body temperature E. Diarrhea

C. Cough

11. Effective serologic test for detection of maternal antibodies to parvovirus in puppies

A. HA B. HI C. CFT D. AGPT E. FAT

12. Ebola virus can infect animal with exception;

B. Gorillas B. Chimpanzees C. Antelop D. sheep E. Monkey

13. The specific binding receptor of ebola virus is;

29

B. Nucleo protein B. Viral protein C. Glicoprotein D. viral protein30 (VP30)

F. Viral protein 40

14. Virological diagnosis of Equine Encephalitis can be done by:

A. virus Neutralization

B. HA test

C. Isolation of virus in the brains of mice and identification with the FAT

D. Polymerase Chain Polymerase (PCR)

E. nucleotide sequencing

15. The sensitivity of serological tests in the diagnosis of Equine Encephalitis are:

A. CFT> Test SN > HI Test

B. SN test> CFT.> HI test

C. HI Test> Test SN> CFT

D. HA Test> Test HI

E. PCR> Sequencing of nucleotides

16. Equine Encephalitis caused by a virus ;

A.The genus Alphavirus, Family Flaviviridae

B. Alphavirus genus, Togaviridae Family

C. Genus Flavivirus, Flaviviridae Family

D. Genus Flavivirus, Togaviridae Family

E. Genus Flavivirus, Family Adenoviridae

17. Host amplifier in the Japanese encephalitis is:

A. Horse B. Human C. Fowl D. Pig E. Bat

18. MCF is characterized by the following properties, except;

A. Caused by bovine herpes virus -3

B. Necrosis and lesions on the oral mucosa

C. Keratoconjunctivitis

D. Encephalitis

E. Blisters on the feet

19. An anthropod vector may be involved in its transmission of this disease :

A. MCF B. Foot and Mouth Disease C. Stomatitis Vesicularis

D. Exsanthema Vesicularis E. Pestis Suum

20. Leucopenia in blood tests can be found in an infected dog:

A. Diarrhea Canine Coronavirus D. Canine Parainfluenza

B. Canine Distemper E. Rabies

C. Canine Parvovirus

II. Answer the following questions by using the key below:

A. if 1,2,3 are correct

B. if 1 and 3 are correct D. if only 4 is correct

C. if 2 and 4 are correct E. if all are correct

28. The strategies of ebola virus infection by animal are

1. Binding attachment factor by receptor to pre membrane cell,

2. GP cleavage protein by cysteine proteases,

3. NPC1 binding with GP1alfa,

30

4. Building viral nucleocapsid

29. Molecule substances, that can mediated of antibody dependent enhancement are;

2. Fc-receptors 2. Integrand 3. C1q-ligands 4. Interferon-gama

30. Ebola virus can infect many cell types including ;

1. monocytes 2. Macrophages 3. dendritic cells, 4. endothelial cells

31. Animals which suffer from Rabies:

1. Cat 2. Horse 3. Goat 4. Chicken

32. Animals that can act as reservoir of Rabies:

1. Wolf 2. Horse 3. Bat 4. Cow

33. Which of the following diseases is/are zoonotic:

1. Rabies 2. Malignant Catarrhal Fever

3. Food and Mouth Disease 4. Feline Distemper

34. Incubation period of Rabies depend on:

1. dose of virus

2. distance from the bite wound to the CNS

3. severity of the bite wounds

4. number of sensory nerves ending

28. Properties of the Equine Encephalitis:

l. Is a zoonotic disease

2, Can be caused by a strain enzootic and epizootic

3. Causative virus has antigenic relationship with Chikungunya virus

4. Many are found in Indonesia

29. Japanese encephalitis virus has antigenic relationship with viruses:

l. West Nile 2. St. Louis 3. Murray Valley 4. Equine enterovirus

30. VEE virus :

l. is viscerotropic 3. Not always lead to encephalitis

2. are neurotrophic 4. Always lead to encephalitis

31. Clinical symptoms of Japanese encephalitis include;

1. Mummified fetuses in pigs 3. Decreased mobility of sperm in male

pigs

2. Long-term neurological disability in children 4. Skin blisters in horses

32. To prevent FMD typeA should be used FMD vaccine:

1.Type O 2. Type C 3. SAT-1 type 4. type A

33. These diseases cause symptoms of diarrhea and erosion of the lining of the oral cavity

l. FMD 2. MCf 3.SV 4. BVD-MD

34. The following disease is transmitted through mosquito bites

l. BVD 2. Vaksinia 3. FMD 4. SV

35. Similarities between the FMD and MCF is/are :

1. The existence of the mouth vesicle 3. Corneal opacities, and neurological symptoms

2. Lesions on the feet 4. Erosion of the mouth mucosa

36. The following is a statement about MCF:

1. Sheep and cattle are sensitive 3. low morbidity

2. Often CNS disorders 4. keratoconjunctivitis

37. The following animals are sensitive to FMD :

1. Cow 2. Pigs 3. Sheep 4. horse

38. The following animals are sensitive to SV :

1. Cow 2. Pigs 3. Sheep 4. horse

39. Serotype of SV disease is describe below

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l. Indiana Type 2. Type Mass 3. New Type Yersey 4. type Asia

40.Feline Calicivirus Disease:

l. Gastrointestinal disease in cats 3. Cause severe diarrhea in kittens

2. Transmission by aerosol 4. Cats can still be recovered as a career

41. The following symptoms can be found in the infected cat with Caliciviruses:

l. Conjunctivitas 2. Rhinitis 3. Epithel ulcerated mouth 4. severe diarrhea

42. Differential diagnosis of Feline Caliciviruses Disease:

l. Feline Panleukopenia 3. Feline parvovirus

2. Feline Infectious Peritonitis 4. Feline Rhinotracheitis

43. Serotype of FMD can be detect by doing the test

1. ELISA 2. CFT 3. FAT 4. SNT

44. Epizootic cycle caused by ebola virus appear sporadically producing high mortality;

1. Non human primates 2. Precede human outbreaks 3. Acute disease

4. Transmission human to human

III. ANSWER the following questions by using the key below:

A. if both statement and reason are true and related cause and effect

B. if both statement and reason are true but not related cause and effect

C. if the statement is true but the reason is false

D. if the statement is false but the reason is true

E. if both statement and reason are false

49. Differential diagnosis of FMD is Stomatitis Vesicularis because SV and FMD caused

by the viruses of the same genus.

50. Ebola virus disease (formerly called Ebola Hemorrhagic disease) is a severe, often fatal,

disease in humans and non-human primates because ebola viruses have the ability to

turn internal organs into a soup that promptly flows out of the body.

51. The incubation period of Rabies are 14 days, because the migration time of the Rabies

virus to reach the central nervous system are fixed.

52. Rabies Fixed virus strain cannot be detect in the dog’s saliva, because the Rabies Fixed

virus strain migrate to the central nervous system by neurons.

49. Epizootic strains caused Equine Encephalitis more harm than Enzootic strain, because

The strain of enzootic of Epizootic Equine Encephalitis is a virus strain that has been

experienced in the natural attenuation.

50. Stomatitis vesikularis called Pseudo FMD because stomatitis vesikularis have clinical

symptoms similar aphthae Epizootika

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Final Semester Exam Infectious Viral Disease II (I.P. VIRAL) Faculty of Veterinary Medicine – Airlangga University Semester : IV Day/date : Thursday, 31 th May 2018 Time : 80 minutes_______________________________________________________ I. CHOOSE ONE OF THE MOST CORRECT ANSWER 1. Prevention of Hard Pad Disease in puppies can use vaccines containing viruses: A. CD B. Rinderpest C. Parvo Virus D. Feline Panleukopenia E. Hepatitis Contagiusa Canis 2. Causes of Hepatitis Contagiusa Canis in dogs: A. Orthomyxovirus B. Paramixovirus C. Pseudomyxovirus D. Parvovirus E. Adenovirus 3. Blue Tongue disease in the most dominant transmission sheep by vector: A. Flies B. Mosquito C. Tick D. Culex E. Ectoparasit 4. Distemper in young dogs show clinical symptoms below, Except: A. Bronchopneumonia B. Gastritis C. Tie convulsion D. Bloody Diarrhea E. Hepatitis 5. The following statements are about jembrana disease, Except: A. Attack Bali cattle B. Caused by Ricketsia C. There is enlargement and swelling of the lymph nodes and spleen D. There are clinical symptoms of hypersalivation and blood diarrhea E. Transmitted by arthrpoda vector 6. The following statement is about MCF disease: A. The cause is Picornavirus B. Occurrence of erosion lesions in the oral cavity and scrambled C. The causative virus has an antigenic relationship with the suum pestis D. Clinical symptoms include nephephalitis E. Viruses can be grown on TAB 7. The following statement is character of BVD-MD, except: A. Caused by Arbotogavirus B. Can be adapted on pig kidney cell C. Certain serotype can be aglutinate erythrocytes D. Can be cultivated in embryonated egg E. There is antigenic relationship with pestis suum 8. Leucopenia in blood examination was found in; A. Rinderpest D. Jembrana B. MCF E. FMD C. BVD-MD 9. The spread of west nile virus in animals is through vectors: A.Culex sp D. Anopheles sp B. Aides Aegypty E. Stomoxys Calsitrans C. Aides Albopicus

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10. The laboratory diagnosis of west nile virus infected animal is the following methods: A. PCR B. ELISA C. CFT D. AGPT E. HA-HI 11. This viral infections play a role within "Kennel Cough Syndrome" in dog: A. Parainfluenza virus 1 B. Parainfluenza virus 2 C. Parainfluenza virus 3 D. Influenza A E. Influenza B 12. "Shipping Fever" is often associated with : A. Parainfluenza virus 1 B. Parainfluenza virus 2 C. Parainfluenza virus 3 D. Sendai virus E. Simian virus 5

13. Bacterial infection that often as a secondary infection in Canine Distemper : A. Salmonella B. Pasteurella C. Mycoplasma D. Ecoli E. Bordetella bronchoseptica

14. The presence of leukopenia in blood examination of dog indicates an infection: A. Canine Coronavirus Diarrhea B. Canine Distemper C. Canine Parainfluenza D. Canine Parvovirus E. HCC

15. Protein that has important function when hantavirus infects a cell is :

A. Polymerase protein B. Lipid protein

C. Nucleocapsid protein. D. Glycoprotein E. Matrix protein

16. Sources of west nile disease virus in animals is the following: A. Mouse B. Horse C. Cow D. Deer E.Bird 17. The presence of fluid accumulation of yellow ascites (containing high concentrations of

protein, sometimes fibrin) is one indication of infected cats: A. Feline Calicivirus B. Feline Infectious Peritonitis C. Feline Rhinotracheitis D. Feline Panleukopenia E. Feline Parvovirus

18.Japanese encephalitis caused by: A. Alphavirus B. Flavivirus C. Herpesvirus D. Retrovirus E. Enterovirus 19.Characteristic of Enzootic Bovine leukosis is described bellow, except: A. Occurred in all sex and breed cows (beef and dairy) B. Common in dairy cattle than beef cattle C. Contagious for human D. Affected lymphoreticular system E. Disease characterized by persistent and malignant 20. Enzootic Bovine leukosis is caused by: A. Herpesvirus B. Coronavirus C. Rhabdovirus D. Enterovirus E. Retrovirus 21. Which of the symptoms are not for Aujeszky’s Disease A. Urticaria B. Paralyse of the pharynx C. pigs are the main host D. haemorrhagic diarrhea E. Affect animal become furious

22. The synonym of Pseudorabies is: A. Hog Cholera B. Lyssa C. Pseudoaphtae D. Pestis suum E. Aujeszky’s Disease

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23. Here is the nature of rinderpest disease, Except: A. Clinical symptoms include bloody diarrhea B. The virus has an antigenic relationship with distemper and measles C. Virus can be adapted to TAB D. High mortality E. Caused by herpetoviridae virus 24. The following is about FMD, Except: A. Clinical Symptoms of hypersalivation and lameness B. Caused by picornavirus C. Cause high economic losses D. High mortality E. There are serotypes such as A, O, C 25. Prevention of hantavirus disease can be done by means of vaccination with this type of

vaccine, except A. Inacactivated vaccine C. DNA vaccines B. Recombinant vaccines with E coli D. Rodent brain derived E. Active vaccine

26. Correct statement about the disease Bovine Ephemeral Fever: A. Horses can not be infected B. is transmitted through saliva C. mortality can reach 80% D. Nerve abnormalities result in paralysis E. There are blisters on the mucosa of the lips and tongue

27. Which of the folloving symptoms of Hog Cholera is false: A. Encephalitis B. Pneumonia C. Button ulcer on the colon mucosa D. Diarrhoea E. hemorrhages of serous membranes and subcutan 28. BEF can be diagnosed with these methode, except: A. SNT B. CFT C. FAT D. HA and HI-test E. Virus isolation and Identifikation

II. Answer the following questions by using the key below:

A. if only 1,2,3 are correct

B. if only I and 3 are correct D. if only 4 is correct

C. if only 2 and 4 are correct E. if all are correct 29. The most susceptible animal to Srapie is: 1. Cow 2. Goat 3. Buffalo 4. Sheep 30. The following disease is transmitted through mosquito bites: 1. BVD-MD 3. FMD 2. Rinderpest 4. Stomatitis vesikularis 31. The pathological changes caused by BVD-MD are: 1. Lymphoid tissue damage 3. Erosion and ulsera of the digestive tract 2. Balamitis 4. Encephalitis

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32. Clinical manifestations of hantavirus infection in animal : 1. Hemorrhagic fever with renal syndrome 2. Nephropatia 3.pulmonary syndrome 4. Paralysa

33. Inoculation of this virus on the footpad cavia cause vesicula: 1. MCF 2. Stomatitis vesicularis 3. Rinderpest 4. FMD

34. Pathological changes caused by FMD virus : 1. Lymphoid tissue damage 3. Erosion and ulsera of the digestive tract 2. Encephalitis 4. Heart degeneration

35. Characteristic of HCC: 1. Inflammation of the liver 2. Cloudy corneas on both eyes 3. Inclusion of the intranuclear 4. Low mortality 36. The following clinical symptoms are typical symptoms of orf disease: 1. Lesions on the nose 2. Ear lesions 3. Lesions on the vulva 4. Blue tongue 37. Typical HPD are: 1. Inclusion of intrasitoplasmic body 2. Bifasis fever 3. Inflammation of the liver 4. Hyperkeratosis 38. Animals are the most susceptible to Scrapie is:

1. Cow 2 goats 3. Buffalo 4. Sheep 39. This below which includes the properties of prions are: 1. Smaller than the virus 2. Not been characterized by complete 3. Infectious protein particles 4. Unstable 40. Accurate method that can be used to detect BSE is: 1.Immunohistochemistry 2. Western blotting 3. ELISA 4. CFT 41. This below that the general properties of the poxvirus are: 1. Survive for years in dust 2. Containing more than 30 different structural proteins 3. Replication intracytoplasmic 4. Not durable in dust 42. The following clinical symptoms are seen in distemper dogs 1. Respiration 2. Digestion 3. Neurology 4. Fever is based 43. Specific clinical symptoms of blue tongue in infected animal is: 1. ulceration and lesions in the mouth 2 swollen tongue and cyanotic 3. Feet coronitis 4 feet lameness 44. Samples used for the purpose of virus isolation from chickens infected with avian

influenza: 1. Swab trachea 2. Blood 3. Swab Cloaca 4. Serum 45. Interstitial pneumonia in cattle due to parainfluenza infection 3 often accompanied by viral I Infection: 1. Virus adeno 2. IBR virus 3. Bovine respiratory syncytial virus 4. Virus rinderpest 46. Differences between influenza A and B viruses are present in proteins: 1. Protein H 2. Protein NP 3. Protein N 4. Protein M 47. The following symptoms appear in parvovirus infected puppies: 1. Vomiting 2. Corneal opacity 3. Diarrhea profus 4. Tic Convulsion 48. Venezuelan Equine Encephalitis has the following properties

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1. High mortality 2. No death 3. Neurotrophic 4. Viscerotropic 49. Disease can be confused with Equine Encephalitis is: 1.Tetanus 2. Rabies 3. Botulismus 4. Japanese Encephalitis

50. Eastern Equine Encephalitis vectors are describe below : 1. Aedes 2. Mansonia 3. Culex 4. Culiseta melanura 51. Important variant of Equine Encephalitis virus which cause epizootic in America: 1. Subtype IA 2. Subtype IB 3 Subtype IC 4. Subtype II (Everglades) 52. Genital form of Infectious Pustular Vulvovaginitas accomplished by using the following . statement, except: 1. Ecephalitis 2. Genital mucous hyperemia with 1-2 mm vesicle 3. Red nose 4. Balanophostitis 53. Differential diagnosis of Infectious Bovine Rhinotracheitis are: 1. Enzootic bronchopneumonia 2. Bovine Viral Diarrhea (BVD) / mucosal disease (MD) 3. Gangrenous coryza 4. Rinderpest

54. Enzootic bovine leukosis is transmitted through: 1 Horizontal Transmission 2. Infected blood. 3. Vertical transmission 4. Insect bite

55. Characteristic of ebola disease in monkeys are marked by; 1. Bleeding 3. Abnormal blood coagulation 2 Paralysis 4. Profuse diarrhoe

56. Clinical symptoms in dogs and cats infected with west nile virus is ; 1. Fever, depression 3. Paralysis 2. Muscle weakness 4. Myocarditis

57. Desinfectant against contaminants pox virus that are either: 1. Sodium hipochloride 3. Detergent 2. Phenol 2% 4. Formalin 1%

58. The following diseases in Indonesia are: 1. Three Days Fever 2. Rinderpest 3. Pseudorabies 4. Mouth and Nail Disease

59. Bovine Ephemeral Fever Transmission Can occur through: 1. orally 2. per inhalation 3. fecal-oral route 4. mosquito bites

60. To prevent Hog Cholera, piglets can be given: 1. Live vaccine 2. Killed vaccine 3. Combination of Antisera and live vaccine 4. Combination of Antisera and killed vaccine 61. Statement about Hog Cholera virus are are true: 1. Hog Cholera virus consist only one strain/serotype 2. can be ready inactivated by lipid solvent

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3. cross reacted with Mucosal Disease virus 4. can be cultivated in chicken embrionated eggs by allantoic sac route 62. Characteristic for Bovine Ephemeral Fever are:

1. Transmitted by mosquitos 2. Morbidity rate great as 80% 3. Only cow and buffalo are affected 4. Can be transmitted by direct contact

63. Synonym of BEF is/are: 1. Three day sicknes 2. Bovine epizootic fever 3. Stiff sicknes 4. Bovine catarrhal fever

64. These animals can act as reservoir in Rabies: 1. Wolves 2. Horses 3. Vampire 4. Cows 65. The symptoms of Rabies which is often overlooked:

1. Paralytic 2. Prodromal 3. Excitability 4. Behavior changes

III. ANSWER the following questions by using the key below: A. if both statement and reason are true and related cause and effect B. if both statement and reason are true but not related cause and effect C. if the statement is true but the reason is false D. if the statement is false but the reason is true E. if both statement and reason are false

66. The dog recovered from HPD will be immune to CD BECAUSE as the HPD virus has the

same antigenicity as the CD virus

67. During the incubation period of rabies virus infection, antibody responses were undetected, BECAUSE rabies virus spread to the CNS via nerve fibers.

68. Active parvovirus vaccine should not be administered to a pregnant cat BECAUSE as an active vaccine contains an adjuvant

69. Bovine Enzootic bovine leukosis common in mature cow, especially those in the culling,

BECAUSE Enzootic bovine leukosis not contagious for humans.

70. The first replication virus if infected with the smallpox virus in squamous epithelium, BECAUSE smallpox virus viremia occurred after multiple infections in the skin epidermis.

71. Cow pox can attack humans with clinical symptoms of pocks on hand BECAUSE, cow pox also attack cat with crater clinical symptoms like ulcers

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72. Orf is a disease in sheep known as scabby mouth BECAUSE, ORF causes lesions on the lips of sheep and crusta

73. The differential diagnosis of Orf is blu tongue disease BECAUSE The two diseases are similar

74. Blue tongue is a disease of ruminants as hospes primer is the goat, BECAUSE Blue tongue is an contagious disease of cattle, sheep and deer.

75. Eastern Equine Encephalitis virus is a member of the genus flavivirus BECAUSE, Japanese encephalitis virus is a member of the family Flaviviridae

76. Blue tongue disease is caused by the family reoviridae virus and has blue tongue symptom. BECAUSE The blue tongue virus has 24 serotypes

77 The Morbidity rate of BEF is low, BECAUSE BEF is transmited by mosquitos. 78. Pseudorabies is also known as Mad Itch Disease, BECAUSE generally pigs infected with

Pseudorabies shown CNS disorder. 79. Hantavirus can be secreted through excreta aerosol mice because hantavirus can be

horizontal transmited in mice 80. Hypersalivation can be seen in Dogs infected with Rabies virus, BECAUSE the replication

of Rabies virus take place in salivary gland

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