OpenLAB CDS ChemStation Edition Overview
Jon Welsh Agilent Informatics
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How Does OpenLAB CDS ChemStation Edition Address Other Lab Needs? An Enterprise-wide Chromatography Data system • Fully scalable from stand-alone workstation to Distributed System • Easily connects to Data Store or ECM for central data storage and regulatory
compliance with GLP/GMP and 21 CFR Part 11 • Multi-technique: Control of Agilent GC, LC, CE, LC/MS, CE/MS, SFC • Tight instrument integration • Flexible report generation tools for custom calculations, sequence summary and
single run reporting • Macro language
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OpenLAB CDS Workstation Configuration
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OpenLAB CDS: Networked Workstation Configuration
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OpenLAB CDS: Fully Distributed Configuration
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OpenLAB CDS ChemStation Edition – A Scalable Part of the LI Family Features
• All Data and Methods generated by any version of ChemStation rev. B are compatible.
• The UI and workflow of OpenLAB CDS is very familiar and doesn’t change in scaling or adding Data Store or ECM for storage.
Benefit
• Customers have a smooth migration path from single workstation to a Networked System with or without Data Store / ECM.
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Multi-Technique Instrument Control
Many Instruments - One Enterprise Software
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• One user interface • Lab-at-a-glance view of the lab • Identical look & feel – independent of
the hardware • Easy to learn and use • Central administration • Central place to configure data storage
Roles & Privileges
• ChemStation roles and privileges are managed in OpenLAB Control Panel and can be used without OpenLAB ECM or Data Store.
• Support for local and domain user authorization.
• Grouping of instruments into locations.
• Define access security for each location in the tree.
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Data Organization – What’s in a Result Set?
• The master method is copied at the start of the sequence to create a sequence method.
• Any changes made during data analysis (e.g., during an update of the calibration table) are saved into the sequence method.
• The acquisition method is stored in ACQ.txt.
• The individual Data Analysis Method (DA.M) preserves the last data analysis parameter to re-create the last version of the results for a specific data file.
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Usability: Introducing Workflows
Review View • ChemStation Review View • Uses Intelligent Reporter to show results
Data Analysis View
Recalculation Mode - Flexible • Recalculate peak results in the navigation table with one or several different methods • Shortcut to recalculate all data in the navigation table with a single method • Manually step through navigation table or use auto-stepping to review
Reprocessing Mode - Traceable • Reprocess the sequence with different method(s) to update or modify calibration • Add new or changed methods to result set and reprocess the whole or partial sequence • Store and manage all result and method revisions with sequence/result set
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Review View
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Key Benefit: Preview or print reports without reprocessing and get your reports 10 times faster!
Select report template(s) and data-files and get
immediately answers on complete experiments!
Recalculate Mode
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Any method can be loaded from the tree
“autostepping” toolbar
Switch between Recalculation and Reprocessing Mode
“Recalculate” menu
Key benefit: quickly apply multiple methods to a self-defined set of runs
Reprocess Mode
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New tree with current sequence methods; quickly add master methods to the result set
Key benefit: Easy way to reprocess and recalibrate complete sequence
Switch between modes “sequence reprocessing” toolbar
Self-Assembled Data Sets and Result Sets
Self-assembled Data Set
• Use “Add” functionality to add data from different sources
• Reprocess/recalculate and report over self-assembled set of data assembled from different folders [not possible in strict 21 CFR part 11 workflow!].
Self-assembled Result Set
• A self-assembled data set can be turned into a self-assembled result set.
• Always available for cross-sample calculations and uploading into Data Store or ECM.
• Supports cross-sequence review in 21 CFR part 11 workflow
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• Select data files in the navigation table
Self-Assembled Result Set
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• Select the method and destination folder • Launch Create New Result Set… dialog
Sequence Queuing
• The Run Queue now also supports ChemStation sequences. You can directly schedule a single sequence, or process all sequences given in a Queue Plan.
• Select a sequence template to be added to the queue (online only)
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Run Queue • Single Samples can now
be added to the Run Queue.
• Run Method / Run Sequences are submitted to the queue.
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Queue Planner
• The Queue Planner allows setting up the relevant sequences and queueable pauses in a queue plan
• Load, create and save queue plans (as *.qpl file)
• Available in online and offline
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Queueable pause
Easy Sequence
Native Sequence
METHOD HANDLING
OpenLAB CDS ChemStation Edition
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Method Download
• Upon instrument startup, users are given a choice: • download the ChemStation
method to the instrument • upload the instrument method
to ChemStation • create a new method from
instrument method • A differences viewer highlights
the differences between the ChemStation method and the instrument method.
OpenLAB CDS ChemStation Edition – Acquisition Method Viewer Problem I need to review the Acquisition Method parameters before downloading to the instrument. I do not want to trigger Method Resolution.
Solution Acquisition Method Viewer-provides a way to view the acquisition method parameters.
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OpenLAB CDS ChemStation Edition – Single Sample Workflow • The Navigation Table now shows the acquisition method as
well as the data analysis method.
• A fly-over indicates the path to the data analysis method.
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OpenLAB CDS ChemStation Edition
STORAGE OPTIONS
Storage Option Review
File System
• Simple configuration supports Workstation and Networked Workstation
Data Store
• Compliant workgroup solution: Compliance with GLP/GMP and 21 CFR part 11
• Includes sophisticated search support
ECM
• The Enterprise data repository
• Compliance with GLP/GMP and 21 CFR part 11
• Includes sophisticated search support
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• Download any result set or single run from Data Store (or ECM) to the local ChemStation file system.
• The downloaded data can be reviewed and reprocessed, since the result set contains all necessary files.
Data that have been uploaded to Data Store (or ECM) have a different icon in the tree view.
OpenLAB CDS ChemStation Edition – Integration with Data Store or ECM
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For more Information
OpenLAB CDS ChemStation Edition web page
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Title: Agilent OpenLAB CDS eFamiliarization DVD P/N: M8301-60032 This DVD includes a set of eFamiliarization modules for OpenLAB CDS ChemStation and EZChrom Editions Literature Type: DVD Language: English (currently shipping) Chinese & Japanese (ships in Feb. 2014) Target Audience: Agilent customers who need basic overview of the software operations and functions.
What’s New in OpenLAB CDS A.01.06
Support for Windows 7 and 8
Improvements to sequence handling
• Refreshed Sequence Table [CS]
• Full sequence rollout [CS]
Targeted Customer & Support Enhancements
• Improved bar code handling [CS]
• Recoverable error handling for GC
• Improved display of driver versions
Instrument Control
Intelligent Reporting Updates
OpenLAB Data Analysis A.01.02 • Expand support for HPI • Integration with Data Store
Integration with OpenLAB Data Store A.02.01 • Expansion of database compatibility to
PostgreSQL
OpenLAB CDS Secure ChemStation Workstation [CS] = ChemStation Edition [EE] = EZChrom Edition
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OpenLAB CDS A.01.06 Agilent Restricted
Customer Experience
• Stop the GC and Continue the Sequence
• Recoverable error handling
Continue Abort and Continue Queue Abort
Skip Pause Abort and Continue Queue Abort
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Customer Experience
• Improve customer experience of ChemStation sequence table [CS]
• Sequence rollout [CS]
Barcode Reading – Chain of Custody
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• Enter sample information including the sample name into the sequence table
• 7693 ALS with 7890B reads barcode
• CDS compares the Barcode field (Actual) to the sample name (Expected) and determines mismatched values
• Logic determines whether to inject or not and prints results on the reports
• True = prints “barcode match” • False = prints “barcode
mismatch” ChemStation Edition
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