Glucose OxidaseGlucose OxidaseElectrochemically Sensing Electrochemically Sensing

GlucoseGlucoseOrOr

How Far Can You Throw an How Far Can You Throw an Electron?Electron?

SensorsSensors

Soluble Mediators

•Ferrocenes

•Quinones

•Ruthenium amines

•Ferricyanide (?)

•Hexacyanoruthenate

Modifiers

•Electrode

•4,4’-bipyridine

•Enzyme

•Heller’s Wired Systems

Ni[Ru(CN)Ni[Ru(CN)66]]2-/1-2-/1- CME CME

R1

CPE

R2

€

Y * ω( ) =YO iω( )n

YO ≈ Cdl

Double Layer Analysis

Analytic Glucose Detection

€

kET ≈1013 exp −β d − 3( )( )exp −ΔGo + λ( )

2

4RTλ

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