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Page 1: Germ Busters

Germ BustersGerm Busters

A game of life or death.A game of life or death.

Page 2: Germ Busters

Two deadly foes – only one will Two deadly foes – only one will survivesurvive

Bacteria need a suitable environment Bacteria need a suitable environment to grow and reproduce.to grow and reproduce.The body provides such an The body provides such an environment.environment.

In order to survive the body must In order to survive the body must protect itself from harmful bacteriaprotect itself from harmful bacteria

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Team 1 – The BodyTeam 1 – The Body

DefencesDefences– SkinSkin– Nose ToxinsNose Toxins– AntibodiesAntibodies

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Team 2 – BacteriaTeam 2 – Bacteria

Reproduce quicklyReproduce quickly

Aim to overtake the body and kill the Aim to overtake the body and kill the host.host.

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The personalitiesThe personalities‘‘Bacteria Queen’Bacteria Queen’ ‘‘The Brain behind The Brain behind

the Body’the Body’

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Two paths – one goalTwo paths – one goalTo reproduce To reproduce bacteria need a bacteria need a suitable suitable environment such environment such as the body. The as the body. The first obstacle to first obstacle to overcome is the overcome is the body’s outer body’s outer defence layer – defence layer – either the skin or either the skin or the nose.the nose.

Antibodies

Skin Nose

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Phase 1 – The skinPhase 1 – The skinBacteria need to Bacteria need to shoot goals through shoot goals through netball hoops – this netball hoops – this represents bacteria represents bacteria getting through getting through pores and cuts in the pores and cuts in the skin.skin.Once a bacterium Once a bacterium has shot a goal, has shot a goal, he/she can move on he/she can move on to the next phase.to the next phase.

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Phase 1 – The nosePhase 1 – The nose

The warm moist conditions of the nose The warm moist conditions of the nose may seem like an ideal place for the may seem like an ideal place for the growth of bacteria. However, the growth of bacteria. However, the liquids produced by the cells lining the liquids produced by the cells lining the nose contain substances which kill nose contain substances which kill most bacteria.most bacteria.

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Bacteria must run through the nasal Bacteria must run through the nasal passage gauntlet without being hit passage gauntlet without being hit by a ball (toxin). Nose cells must try by a ball (toxin). Nose cells must try and hit bacteria below the waist.and hit bacteria below the waist.

Phase 1 – The nose (cont.)Phase 1 – The nose (cont.)

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Phase 2 – The immune systemPhase 2 – The immune system

If bacteria penetrate the skin they If bacteria penetrate the skin they find the moist, warm conditions ideal find the moist, warm conditions ideal for growth. When this happens our for growth. When this happens our immune system comes into action.immune system comes into action.

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Goal of the bacteriaGoal of the bacteriaBacteria need to Bacteria need to walkwalk across the tennis across the tennis courts without being courts without being stopped by an stopped by an antibody. Their goal antibody. Their goal is to reach the fence. is to reach the fence. If 10 bacteria can If 10 bacteria can reach the fence, this reach the fence, this will represent will represent successful invasion of successful invasion of the body andthe body and the the bacteria will win bacteria will win the game!the game!

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Goal of the antibodiesGoal of the antibodies

Antibodies are special types of Antibodies are special types of proteins designed to attack the proteins designed to attack the surface of a particular pathogen. surface of a particular pathogen. They can attach to the cell wall of a They can attach to the cell wall of a bacterium and disable it.bacterium and disable it.

Antibodies can Antibodies can runrun, but they can , but they can only disable a bacterium if they can only disable a bacterium if they can match its protein coat code.match its protein coat code.

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Cracking the protein codeCracking the protein codeBefore the game, the bacteria will decide Before the game, the bacteria will decide on a number between 1 and 10. All of the on a number between 1 and 10. All of the bacteria have the same number.bacteria have the same number.

When an antibody tags a bacterium, When an antibody tags a bacterium, he/she needs to guess a number between he/she needs to guess a number between 1 and 10. If the antibody guesses the 1 and 10. If the antibody guesses the correct number, the bacterium is disabled correct number, the bacterium is disabled and must sit down. If the antibody and must sit down. If the antibody guesses an incorrect number it cannot guesses an incorrect number it cannot approach that same bacterium again.approach that same bacterium again.

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Antibody queueFence (the goal)

bacteriumNo 6?

Start line

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Strategy considerations - BacteriaStrategy considerations - Bacteria

You may benefit by focusing your You may benefit by focusing your attacks on one part of the body to try attacks on one part of the body to try and overwhelm its defences.and overwhelm its defences.

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Strategy considerations - BodyStrategy considerations - Body

How many people should be How many people should be allocated to defend the nasal allocated to defend the nasal passage? (you will only have 5 nerf passage? (you will only have 5 nerf balls)balls)

How many people should be How many people should be allocated to be antibodies?allocated to be antibodies?