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Women’s Health in Women’s Hands: The Promise of MPTs

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2 July 2014  Felicia Stewart Center at UCSF ANSIRH  Oakland, California, USA. Women’s Health in Women’s Hands: The Promise of MPTs. Special Guests: Manjula Lusti-Narasimhan (WHO) Ina Park (CDPH) Bethany Young Holt (CAMI/IMPT). Multipurpose Prevention Technologies. - PowerPoint PPT Presentation

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Special Guests:Manjula Lusti-Narasimhan (WHO)Ina Park (CDPH)Bethany Young Holt (CAMI/IMPT)Womens Health in Womens Hands:The Promise of MPTs2 July 2014 Felicia Stewart Center at UCSF ANSIRH Oakland, California, USA

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaMultipurpose Prevention Technologies

MPTs prevent a combination of unintended pregnancy, STIs, HIV/AIDSShould be safe & easily availableAre designed with key input from women for their specific needs & preferencesWomens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California2

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California3Whats in the pipeline?Small Organic MoleculesBroad Spectrum Natural ProductsProteins/PeptidesNon-Hormonal Contraceptives

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaTalking Points:While condoms do prevent both pregnancy and STIs if used correctly and consistently, many new methods are planned or are already in the pipeline.

Emerging Multipurpose Prevention Technologies:Drug combinationsDrug & device combinationsBacterial therapeuticsMultivalent vaccinesNanoparticals

4WHO Global Reproductive Health Strategy

Promote and strengthen SRH services through:improving antenatal, delivery, postpartum and newborn care;providing family planning, including infertility services; eliminating unsafe abortion;combating STIs, including HIV, RTIs, cervical cancer and other gynaecological morbidities;promoting sexual health.

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California5Global Need222 million women have an unmet need for modern contraception.Each day, close to 800 women in developing countries die from complications related to pregnancy and childbirth. Each year 1.7 million people die from AIDS related causes and 2.5 million become newly infected with HIV.1 million people contract a sexually transmitted infection every day.

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California6WHO/RHR/HRP Core FunctionsIdentifying gaps and priorities and shaping the global SRH research agendaProviding leadership on matters critical to improving SRH through knowledge generation, synthesis and managementSupporting national research, technical capacity strengthening and engaging in relevant partnershipsArticulating ethical and evidence-based options for policy formulation and programme development to improve SRH, in collaboration with regional and country officesMonitoring and evaluation of SRH situations and trends, advocacy, catalysing change and supporting intervention deliveryDeveloping of WHO guidelines: clinical standards, norms and related policy and technical guidance documentsDeveloping pre-qualification of products

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California7Case Study: KajiataAge 33, marriedLives in region with high rates of HIV and HSV-1Already has 6 childrenCurrently gets the Depo injectionHusband spends a significant amount of time out of the village and she accepts he is unfaithfulHusband will not wear a condom

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaCase Study: AngieAge 19Lives in region of the US with high incidence of chlamydiaCurrently using long acting reversible contraception No longer in a committed relationshipDoesnt always use a condom

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaConsequences of STIsSTIs enhance the biological risk for HIV infection and transmission and can impact how the disease progresses.Long-term health consequences of STIs include:Cervical cancerPelvic inflammatory diseaseInfertilityTubal or ectopic pregnancyInfants born to infected mothers can suffer from perinatal or congenital infections.

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaIn the United StatesNearly half of all pregnancies among American women are unintended.STIs are the most commonly reported communicable diseases in the US.There are18.9 million new cases of STIs each year in the US, half of them among 15-24 year olds.

Source: Guttmacher Institute

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaThe disconnect between these intrinsictly linked SRH indications are not just problems in the developing world but here in the US as well. As providers I am sure you are very familiar with these stats:

For reasons that seem to have to do with politics and funding mandates than biology and the intrinsic link between risk of unintended pregnancy and risk of an STI, reproductive and sexual health prevention approaches tend to be focused on specific health indications and is often very compartmentalized rather than addressing the women and girls SRH needs in a more realistic and comprehensive way.

A women who needs contraception and is at risk of an STI, for example, often needs to seek care for each from different providers and different facilities making access and effectiveness a challenge.

11Chlamydia, Gonorrhea, and Primary & Secondary SyphilisCalifornia Rates, 19902012

ChlamydiaGonorrheaP&S Syphilis7.8(N=2,936)89.3(N=33,780)448.9(N=169,797)>206,000 cases of bacterial STIs reported in CaliforniaSelected STIs in California

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaMistimed or Unwanted PregnancyMIHA 2011

Nearly 1/3 of pregnancies in CA are unplanned

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaChlamydia Among Females, 2012 Ages 15-24, By County

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California

Chlamydia among females (2012) vs Unplanned Pregnancy (2011) LA CountySoutheastern CASan Joaquin Valley

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaGenital HerpesInitial Visits to Physicians Offices, 19662012NOTE: The relative standard errors for genital herpes estimates of more than 100,000 range from 18% to 30%. SOURCE: IMS Health, Integrated Promotional Services . IMS Health Report, 19662012.

2012-Fig 48. SR, Pg 45

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaSTIs in WomenWomen are disproportionately affected by genital herpes

1 in 9 men1 in 5 womenSource: CDC MMWR April 23, 2010 / 59(15);456-459

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaWhat you can do?SHARESpread the news about life saving MPTs with your colleagues and networks. Visit our website to access factsheets, PowerPoint presentations, MPT meeting reports and other resources.

COLLABORATEJoin the IMPT and help move the research, policy, funding and education efforts forward to save lives learn more on our website.

CONTRIBUTEYour financial and in-kind support can accelerate MPT education, research and introduction.

Visit www.cami-health.org or www.MPTs101.org to learn more!Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California

Collaboration, advocacy & research to advance MPTsWomens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaTALKING POINTSCAMI guides a global initiative intersecting science, industry and education to drive a new generation of technologies that address the link between unintended pregnancy and multiple health risks, including HIV, associated with unsafe sexual activity.

2) This global partnership is called the Initiative for Multipurpose Prevention Technologies (IMPT).Begun in 2009, the IMPTs approach for achieving successful MPT research and introduction is through a highly structured collaborative effort that involves numerous stakeholders who may otherwise not have the opportunity to exchange information and collaborate. Stakeholders include basic scientists working in contraception, HIV and other STIs; product developers and manufacturers; social and behavioral scientists; market researchers; health advocates and health care providers; and public and private funders.

19Collective Impact Approach

Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California

Questions?Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, CaliforniaAcknowledgementsBill & Melinda Gates FoundationMary Wohlford FoundationUSAIDWorld Health OrganizationThe generous support from individual donors like you!Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California

Support for this project is made possible by the generous support of the American people through the United States Agency for International Development (USAID) under the terms of the HealthTech Cooperative Agreement #AID-OAA-A-11-00051, managed by PATH. The contents are the responsibility of CAMI/PHI and its partners and do not necessarily reflect the views of USAID or the US Government.

Thank You!Womens Health in Womens Hands: The Promise of MPTs2 July 2014 Oakland, California

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