Poster Presentations 349

however, their potential BCVA is unknown and may belimited by their ocular pathology.Conclusion: Increased research in the area of anisometropicamblyopia secondary to unilateral high myopia appears tobe revealing different subcategories of the underlyingphenomenon causing the decreased vision. By acknowl-edging these subcategories and understanding the pro-cesses, the treatment modalities of these patients maystart to differ. Although traditional amblyopia treatment issuccessful in many of these anisometropia patients, it isimportant to identify and acknowledge the role of retinalstructural abnormalities to be able to better predict the finalvisual prognosis.

Poster 5

Why Does My Kid Look Like That?!

Erica Oosting Zeiders, O.D., Illinois College of Optometry/Illinois Eye Institute, Chicago, Illinois

Background: Nystagmus is present in 0.02% of the pop-ulation; 80% of those cases are congenital and the other20% are acquired. The 3 important descriptions of nystag-mus are type, amplitude, and frequency. Visual acuityaverages 20/60, but can be as poor as 20/200. Conditionssuch as albinism, Leber’s congenital amaurosis, achroma-topsia, spasmus nutans, and other conditions affecting thevisual pathway from the cornea to the retina must beconsidered.Case Summary: A 21-month-old white male presented withhismother. She stated she had noticed at 16months old, her sonhad started turning his head to the right mostly while viewingdistant objects. His birth and developmental history werenormal, and his family andmedical historywere unremarkable.The child didn’t seem to be bothered by this new head postureand there had been no head nodding. A jerk nystagmus with anull point in left gazewasnotedduring the exam,with relativelyequal visual acuities O.D., O.S. Refraction, external, andinternal exams were unremarkable and no strabismus wasnoted.A referral was made to a pediatric ophthalmologist for consul-

tation.At thisvisit, themotherwas instructed topayattention toherson’s nystagmusover the next 12months and to return to the clinicif any changes were noted. Surgery was not recommended at thistime, and additional imaging was not ordered. Vision therapy andcontact lenses were presented as an option for the future.Conclusion: Some pertinent findings in congenital nystag-mus include the onset by age 6 months, the presence of anull point by age 1, a dampening of the nystagmus onconvergence, reversal on opticokinetic nystagmus testing,and an absence of symptoms per the patient.It is important to keep inmind that congenital nystagmus is

a diagnosis of exclusion and all relevant differential diagno-ses should be ruled out. In order to do this, additional imagingshould be ordered or a referral to a pediatric ophthalmologistfor a consultation is recommended. Also, if poor vision isnoted, referral for low vision services is imperative.

Contact Lens

Poster 6

Risk Factors for Corneal Infiltrative Events in Soft ContactLens (SCL) Wearers: A Case Control Study in 2010

Jami R. Kern, Ph.D., John J. McNally, O.D., Lisa Keay,Ph.D., and Robin L. Chalmers, O.D., Alcon Research Ltd.,Fort Worth, Texas

Purpose: To evaluate the association of symptomatic softcontact lens (SCL)-relatedcorneal infiltrative events (CIEs)withSCL material, lens care products (LCP), and other risk factors.Methods: Cases with symptomatic CIEs were identified in aretrospective,multicenter case control study at 5 academic eyecare centers in theU.S. andCanada. Each casewasmatched to3 controlswhohad received eye care near the time of the case’slast exam at that center. Controls wore SCLs but were notmatched for demographic or SCL factors. Clinical diagnoseswere established by an expert panel whowere masked to SCLand LCP brands. Univariate analysis was conducted and anyfactors that were significant at the p5 0.20 level were placedin a multivariate conditional logistic regression model. Inter-actions were tested by removing all daily disposable (DD)and all extended wear (EW) cases in separate models.Results: Clinical records from 166 patients with symptomaticCIEs and known EW status were reviewed, adjudicated, andanalyzed. Caseswore. 50 SCL brands and. 10LCP brands.Age, increasing CL Power, EW, reusable SCLs, siliconehydrogels and student statuswere significant univariate factors.In the multivariate, age (1.05X/year; 1.03, 1.06 95%C.I.), EW(4.18X, 2.44, 7.15) and Reusable SCL (6.27X, 1.88, 20.97)were significant. Among daily wearers, the only significantfactors were age (1.05X/year, 1.03, 1.08), reusable SCLs(11.48X, 1.41, 93.49) and silicone hydrogel SCLs (1.94X,1.03, 3.66). Without DD in the model, age (1.04X/year, 1.02,1.06), EW (4.42X, 2.53, 7.71) and silicone hydrogel SCLs(1.80X, 1.01, 3.22) were significantly associated with CIEs.Conclusions: Corneal infiltrative events are positively asso-ciated with younger patient age, EW, and reusable SCLs. Theleading SCL andLCPbrandswere not significantly associatedwith development of CIEs in any model. Among DW users,silicone hydrogels are also significant risk factor for CIEs.(J.K. is an employee of Alcon Research, Ltd. Study spon-

sored by Alcon Research, Ltd.)

Poster 7

Soft Contact Lens Wearers With CL-Related Dryness: CanSoft Contact Lens Care System Impact Symptoms andComfortable Wearing Time?

Jami R. Kern, Ph.D., Robin L. Chalmers, O.D.,Leslie Napier, Ph.D., Chris Hunt, M.Sc., andGraeme Young, Ph.D., MPhil., Alcon Research Ltd., FortWorth, Texas

Purpose: To assess the impact of lens care product (LCP) onsymptoms and comfortable wearing time among soft contact