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Protist, Vol. 159, 3, January 2008 http://www.elsevier.de/protis Published online date 30 November 2007 EDITORS’ CHOICE What is Science and why do We Do It? Every once in a while I try to step back from the ongoing little emergencies and exigencies of lab research and think about the meaning of it all. Why is it at all important to learn exactly how a biological phenomenon occurs and has evolved, how molecules interact, what are the rules that govern the behavior of matter at all levels, how our universe evolved and even how mathematical truths exist? Any why does Society pay us and (sometimes even respect us) to try to learn these things? The second question is easier to answer, especially for biomedical research. Clearly human beings desire long healthy, happy lives and human societies want to perpetrate themselves and this knowledge may aid in achieving these desires. The first question however is difficult and has no easy answers or perhaps any answers at all. I myself feel that knowledge and understanding of the world around us has an inherent worth beyond that of the welfare and happiness of individual humans and groups of humans, although it indeed may prove incredibly important for the very survival of our species, without which knowledge in any sense is meaningless. Knowledge is also self-gratifying and pragmatically useful for future behavior but that is hardly the real reason to do research. But what is this ‘‘inherent worth’’ of knowledge? I equate it with the sense of wonder and beauty that one feels when one finally under- stands how recalcitrant facts fit into conceptual frameworks and new facts are then predicted. This sense of wonder must be tempered by the realization that the theories almost certainly will change and the ‘‘facts’’ reinterpreted, but for that small period of one’s life the wonder and beauty of it all glistens and all striving and daily routines are subsumed. It may sound presumptuous, but that is why I do Science. Larry Simpson Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at UCLA, 6780 MacDonald Building, Los Angeles, CA 90095 1489, USA fax: +1 213 341 2271 e-mail [email protected] ARTICLE IN PRESS & 2007 Elsevier GmbH. All rights reserved. doi:10.1016/j.protis.2007.10.002

What is Science and why do We Do It?

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Page 1: What is Science and why do We Do It?

ARTICLE IN PRESS

http://www.elsevier.de/protisPublished online date 30 November 2007

& 2007 Elsevdoi:10.1016/j

159, 3, January 2008

Protist, Vol.

EDITORS’ CHOICE

What is Science and why do We Do It?

Every once in a while I try to step back from theongoing little emergencies and exigencies of labresearch and think about the meaning of it all. Whyis it at all important to learn exactly how abiological phenomenon occurs and has evolved,how molecules interact, what are the rules thatgovern the behavior of matter at all levels, how ouruniverse evolved and even how mathematicaltruths exist? Any why does Society pay us and(sometimes even respect us) to try to learn thesethings? The second question is easier to answer,especially for biomedical research. Clearly humanbeings desire long healthy, happy lives and humansocieties want to perpetrate themselves and thisknowledge may aid in achieving these desires.The first question however is difficult and has noeasy answers or perhaps any answers at all. Imyself feel that knowledge and understanding ofthe world around us has an inherent worth beyondthat of the welfare and happiness of individualhumans and groups of humans, although it indeedmay prove incredibly important for the verysurvival of our species, without which knowledgein any sense is meaningless. Knowledge is also

ier GmbH. All rights reserved..protis.2007.10.002

self-gratifying and pragmatically useful for futurebehavior but that is hardly the real reason to doresearch. But what is this ‘‘inherent worth’’ ofknowledge? I equate it with the sense of wonderand beauty that one feels when one finally under-stands how recalcitrant facts fit into conceptualframeworks and new facts are then predicted.This sense of wonder must be tempered by therealization that the theories almost certainly willchange and the ‘‘facts’’ reinterpreted, but for thatsmall period of one’s life the wonder and beauty ofit all glistens and all striving and daily routines aresubsumed. It may sound presumptuous, but thatis why I do Science.

Larry SimpsonMicrobiology, Immunology and Molecular

Genetics, David Geffen School of Medicineat UCLA, 6780 MacDonald Building,

Los Angeles, CA 90095 1489, USA

fax: +1 213 341 2271e-mail [email protected]