Abstracts BURNS 361 PLASTICS Altografts of cultured epidermal cells Epidermal cells from dead persons’ skin were grown in culture and formed confluent sheets, which were used to graft deep second-degree burns. The wounds healed within 3 days and remained healthy for 9 months. No stratum corneum appeared in culture but it did appear on the grafts. The method offers a potentially never-ending source of acceptable allografts. Hefton J. M., Madden M. R., Finkelstein J. L. and Shires G. T. (1983) Grafting of burn patients with allografts of cultured epidermal cells. Lancet 2, 428. PATHOLOGY AND EXPERIMENTAL WORK Collagen stimulating factors The authors describe experiments in which 5 collagen stimulating factors have been isolated from healing skin wounds in mice. These factors do not alter fibroblast number but stimu- late prolylhydroxylase activity and collagen synthesis in mouse fibroblasts in vitro. These factors were detectable 3 days after healing and disappeared when healing was complete. The authors consider that these factors play a part in regulating collagen production in healing wounds. O’Hare R. P., Fallon A., Bradley J. F., Burns J. and McGee J. O’D. (1983) Isolation of collagen stimulating factors from healing wounds. J. Clin. Pathol. 36, 707-7 11. Hand reconstruction This is an original review unfortunately without any illustra- tions. The number of cases is large for the highly specialized procedure prescribed. Transfer of the digits from the feet, and use of artificial metacarpi or autogenous metatarsi is mentioned.Grafting with titanium alloy has also been included. The text is difficult to follow without illustration but should be useful reference for those involved in re-implantation surgery and reconstruction surgery of the mutilated hand. (1983) Hand reconstruction. Chin. Med. J. 96. Fibula graft This is a new approach for obtaining a vascularized fibula graft, which will be of interest to those involved in this form of micro-vascular surgery. Seventeen cases are mentioned as part of a preliminary report. (1983) Anterior approach for vascularised fibular graft procurement: A preliminary report. Chin. Med. J. 96. Vascularized free skin grafts A report of 53 vascularized free skin grafts, apparently with excellent results is discussed. Clearly of value with reconstruction of face and hand injuries. (1983) Vascularised free skin grafts. Chin. Med. J. 96.

Vascularized free skin grafts : (1983) Vascularised free skin grafts. Chin. Med. J.96

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Page 1: Vascularized free skin grafts : (1983) Vascularised free skin grafts. Chin. Med. J.96

Abstracts

BURNS

361

PLASTICS

Altografts of cultured epidermal cells

Epidermal cells from dead persons’ skin were grown in culture and formed confluent sheets, which were used to graft deep second-degree burns. The wounds healed within 3 days and remained healthy for 9 months. No stratum corneum appeared in culture but it did appear on the grafts. The method offers a potentially never-ending source of acceptable allografts.

Hefton J. M., Madden M. R., Finkelstein J. L. and Shires G. T. (1983) Grafting of burn patients with allografts of cultured epidermal cells. Lancet 2, 428.

PATHOLOGY AND EXPERIMENTAL WORK

Collagen stimulating factors

The authors describe experiments in which 5 collagen stimulating factors have been isolated from healing skin wounds in mice. These factors do not alter fibroblast number but stimu- late prolylhydroxylase activity and collagen synthesis in mouse fibroblasts in vitro. These factors were detectable 3 days after healing and disappeared when healing was complete. The authors consider that these factors play a part in regulating collagen production in healing wounds.

O’Hare R. P., Fallon A., Bradley J. F., Burns J. and McGee J. O’D. (1983) Isolation of collagen stimulating factors from healing wounds. J. Clin. Pathol. 36, 707-7 11.

Hand reconstruction

This is an original review unfortunately without any illustra- tions. The number of cases is large for the highly specialized procedure prescribed. Transfer of the digits from the feet, and use of artificial metacarpi or autogenous metatarsi is mentioned.Grafting with titanium alloy has also been included. The text is difficult to follow without illustration but should be useful reference for those involved in re-implantation surgery and reconstruction surgery of the mutilated hand.

(1983) Hand reconstruction. Chin. Med. J. 96.

Fibula graft This is a new approach for obtaining a vascularized fibula graft, which will be of interest to those involved in this form of micro-vascular surgery. Seventeen cases are mentioned as part of a preliminary report.

(1983) Anterior approach for vascularised fibular graft procurement: A preliminary report. Chin. Med. J. 96.

Vascularized free skin grafts A report of 53 vascularized free skin grafts, apparently with excellent results is discussed. Clearly of value with reconstruction of face and hand injuries.

(1983) Vascularised free skin grafts. Chin. Med. J. 96.