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Wednesday, April 11 th Thursday, April 12 th Multimedia Room, Life Science Building Session I Aging/CEMMA Chair: Hartmut Geiger (Ulm, D) 8:30 – 9:10 Steven T. Kosak (Chicago, USA) Interstitial t-loops: the interaction of TRF2 and lamin A/C and its role in cellular and organismal aging 9:10 – 9:30 Alberto Catanese (IGradu, Ulm) mTOR-dependent degradative pathways in neuronal biology: Dr. Jeckyll or Mr. Hyde? 9:30 – 9:50 Julian Schwab (IGradu, Ulm) Modelling regulatory processes with qualitative networks 9:50 – 10:30 Peter Tessarz (Cologne, D) Connecting metabolic and epigenetic changes in ageing mesenchymal stem cells 10:30 – 11:00 Coffee Break Session II Cell Biology Chair: Jan Tuckermann (Ulm, D) 11:00 – 11:40 Jean-Pierre David (Hamburg, D) Wnt1: a LRP5-independent bone anabolic Wnt ligand 11:40 – 12:00 Grace Ampem (IGradU, D) The impact of liver X receptors on macrophage self-renewal 12:00 – 12:20 Jin Lu (IGradU, D) Comparative study on extracts of root and bark of eleutherococcus senticosus and their effects on macrophage polarization 12:20 – 12:40 Bozhena Kozak (IGradU, D) Cytoplasmic function of the nuclear receptor: identification of novel interaction partners for GR 12:40 – 13:30 Lunch Break and Poster Session Session III Oncology/HEIST Chair: Thomas Seufferlein (Ulm, D) 13:30 – 14:10 Rodrigo Dienstmann (Barcelona, S) Molecular classification of CRC: cancer cell and microenvironment interactions 14:10 – 14:30 Philp Sander (IGradU, D) Vacquinol-1-induced cell death in glioblastoma involves autophagy/mitophagy and can be engineered to become tumor-specific 14:30 – 15.10 Roland Rad (Munich, D) CRISPR and transposon-based approaches for high-throughput functional cancer genomics in mice 15:10 – 15:50 Oliver Pierre Frappart (Ulm, D) Establishing and using organoids in cancer treatment for response prediction-new perspectives for pancreatic ductal adenocarcinoma treatment in Ulm Multimedia Room, Life Science Building Session IV Trauma Chair: Anita Ignatius (Ulm, D) 9:00 – 9:40 Triantafyllos Chavakis (Dresden, D) Immunometabolic crosstalk in innate immunity 9:40 – 10:00 Silvia Cursano (IGradU, D) A CRH/BDNF dependent pathway mediates hippocampal synaptic loss and memory deficits aſter thorax trauma 10:00 – 10:20 Tamara Merz (IGradU, D) The role of hydrogen sulfide on glucose utilization and mitochondrial function during circulatory shock 10:20 – 11:00 Inge Bauer (Düsseldorf, D) Organ protection by preconditioning: Oscar winner or golden raspberry award? 11:00 – 12:00 Coffee Break and Poster Session Session V Pulmosense Chair: Paul Dietl/Manfred Frick (Ulm, D) 12:00 – 12:40 Matthias Ochs (Hannover, D) Exploring lung morphology 12:40 – 13:20 N.N to be announced 13:20 – 14:00 Gerald Urban (Freiburg, D) to be announced Closing remarks Friday, April 13 th Multimedia Room, Life Science Building Opening lecture Chair: Prof. Dr. Michael Kühl (Ulm, D) 17:0o – Roland Schüle (Freiburg, D) ca. 18:00 The novel histone methyltransferase KMT9 writes the histone mark H4K12me1 and controls metabolism and proliferation of castration- resistant prostate cancer Graduation Ceremony Come-Together-Party

Thursday, April 12 - fakultaet.medizin.uni-ulm.de · Spring Meeting 2018 April 11 - 13 Life Science Building Meyerhofstraße | N27 D-89081 Ulm International Graduate School in Molecular

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Wednesday, April 11th

Thursday, April 12th

Multimedia Room, Life Science Building

Session I Aging/CEMMA Chair: Hartmut Geiger (Ulm, D)

8:30 – 9:10 Steven T. Kosak (Chicago, USA) Interstitial t-loops: the interaction of TRF2 and lamin A/C and its role in cellular and organismal aging

9:10 – 9:30 Alberto Catanese (IGradu, Ulm) mTOR-dependent degradative pathways in neuronal biology: Dr. Jeckyll or Mr. Hyde?

9:30 – 9:50 Julian Schwab (IGradu, Ulm) Modelling regulatory processes with qualitative networks

9:50 – 10:30 Peter Tessarz (Cologne, D)

Connecting metabolic and epigenetic changes

in ageing mesenchymal stem cells

10:30 – 11:00 Coffee Break

Session II Cell Biology Chair: Jan Tuckermann (Ulm, D)

11:00 – 11:40 Jean-Pierre David (Hamburg, D) Wnt1: a LRP5-independent bone anabolic Wnt ligand

11:40 – 12:00 Grace Ampem (IGradU, D) The impact of liver X receptors on macrophage self-renewal

12:00 – 12:20 Jin Lu (IGradU, D) Comparative study on extracts of root and bark of eleutherococcus senticosus and their effects on macrophage polarization

12:20 – 12:40 Bozhena Kozak (IGradU, D) Cytoplasmic function of the nuclear receptor: identification of novel interaction partners for GR

12:40 – 13:30 Lunch Break and Poster Session

Session III Oncology/HEIST Chair: Thomas Seufferlein (Ulm, D)

13:30 – 14:10 Rodrigo Dienstmann (Barcelona, S) Molecular classification of CRC: cancer cell and microenvironment interactions

14:10 – 14:30 Philp Sander (IGradU, D) Vacquinol-1-induced cell death in glioblastoma involves autophagy/mitophagy and can be engineered to become tumor-specific

14:30 – 15.10 Roland Rad (Munich, D) CRISPR and transposon-based approaches for high-throughput functional cancer genomics in mice

15:10 – 15:50 Oliver Pierre Frappart (Ulm, D)

Establishing and using organoids in cancer

treatment for response prediction-new

perspectives for pancreatic ductal

adenocarcinoma treatment in Ulm

Multimedia Room, Life Science Building

Session IV Trauma Chair: Anita Ignatius (Ulm, D)

9:00 – 9:40 Triantafyllos Chavakis (Dresden, D) Immunometabolic crosstalk in innate immunity

9:40 – 10:00 Silvia Cursano (IGradU, D) A CRH/BDNF dependent pathway mediates hippocampal synaptic loss and memory deficits after thorax trauma

10:00 – 10:20 Tamara Merz (IGradU, D) The role of hydrogen sulfide on glucose utilization and mitochondrial function during circulatory shock

10:20 – 11:00 Inge Bauer (Düsseldorf, D) Organ protection by preconditioning: Oscar winner or golden raspberry award?

11:00 – 12:00 Coffee Break and Poster Session

Session V Pulmosense Chair: Paul Dietl/Manfred Frick (Ulm, D)

12:00 – 12:40 Matthias Ochs (Hannover, D) Exploring lung morphology

12:40 – 13:20 N.N to be announced

13:20 – 14:00 Gerald Urban (Freiburg, D) to be announced

Closing remarks

Friday, April 13th

Multimedia Room, Life Science Building

Opening lecture Chair: Prof. Dr. Michael Kühl (Ulm, D)

17:0o – Roland Schüle (Freiburg, D) ca. 18:00 The novel histone methyltransferase KMT9 writes the histone mark H4K12me1 and controls metabolism and proliferation of castration- resistant prostate cancer

Graduation Ceremony

Come-Together-Party

Spring Meeting 2018April 11 - 13

Life Science BuildingMeyerhofstraße | N27

D-89081 Ulm

International Graduate School

in Molecular Medicine

Ulm

Contact

Funded by the Excellence Initiative of the German federal and state governments (GSC 270 »International Graduate School in Molecular Medicine Ulm«)

Impressions

Free Child Care Offered

B 10

H

H

H

HH

H

H

Hochschule Eselsberg 3, 5

Wilhelm-Runge-Str.3, 5, 45

Univ. West3, 5, 45

KlinikenWissenschafts-stadt3, 5, 45

Staudingerstr.3, 5, 45

BotanischerGarten3, 5, 15, 45

Univ. Süd3, 5, 6, 13, 15, 45O22

O23N22 N23N24

N25N26

O25O26 O27 O28

M23 M24M25 N27

Wilhelm

-Runge-Str.

Berliner R

ing

Berliner Ring

Albert-Einstein-Allee

Mähringer Weg

J.-Franck-Ring

Helmholtzstraße

Lehrer-Tal-Weg

Albert-Einstein-Allee

Meyerhofstr.

Oberer Eselsberg

Staudingerstr.

Lise

-Mei

tner

-Str

.

Hochschule

UniversitätBereich West

Science Park II

Science Park I

Daimler AG

Versorgungs-anlage

SportzentrumUlm Nord

Botanischer Garten

UniversitätsklinikumOberer Eselsberg

RichtungStuttgart/MünchenAutobahn A7/A8Ausfahrt Ulm West

Richtung UlmStadtmitte

RichtungJungingen

Universitäts-verwaltung

Freigelände

Gewächshäuser

Bibliotheks-Zentrale

Keine Durchfahrt zur Universität!

Chirurgie

UniversitätBereich OstInnere Medizin

Bundeswehr-krankenhaus

Rehabilitations-krankenhaus

Life Science Building N27

ParkhausHelmholtzstraße

ParkhausAlbert-Einstein-Allee

P

P

We are off ering free on-site child care services for children ages 0 – 12 during the meeting. Pre-registration is required till April 4, 2018. For additional information or to pre-register your child,please contact Lina Zaveleva atPhone: +49 (0) 731 50-36293E-Mail: [email protected]

For visitors it is recomended to park in the red marked car parks

Ulm UniversityInternational Graduate School in Molecular Medicine Ulm

Chairman: Prof. Dr. Michael Kühl

Managing Director: PD Dr. Dieter Brockmann

Coordinator:

Lina Zaveleva, M.A.

E-Mail: [email protected]

Albert-Einstein-Allee 11, O 25 424 | D-89081 Ulm

Phone: +49 (0) 731 50-36293 | Fax: +49 (0) 731 50-36292

www.uni-ulm.de/mm