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PharmacoEconomics & Outcomes News 279 - 9 Sep 2000 The use of thrombolysis is significantly lower in Black patients than in White patients presenting with first acute myocardial infarction in the US, according to US-based researchers. Overall, they found that of 498 such patients (mean age 66 years), Blacks were significantly less likely to receive thrombolysis and β- blockers, but significantly more likely to receive calcium antagonists, than Whites. 319 (64%) of the 498 patients were eligible to receive thrombolysis based on electrocardiographic presentation, although only 227 (71%) of these patients received thrombolysis. Again, eligible Blacks were considerably less likely to receive thrombolysis than eligible Whites, ‘despite similar eligibility by electrocardiography in both races’, comment the researchers. Even in the group of patients ineligible for thrombolysis, ‘whites were twice as likely as blacks to get treated’, they add. Manhapra A, et al. Electrocardiographic presentation of blacks with first myocardial infarction does not explain race differences in thrombolysis administration. American Heart Journal 140: 200-205, Aug 2000 800844091 1 PharmacoEconomics & Outcomes News 9 Sep 2000 No. 279 1173-5503/10/0279-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

Thrombolysis for acute MI more likely if you're White

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Page 1: Thrombolysis for acute MI more likely if you're White

PharmacoEconomics & Outcomes News 279 - 9 Sep 2000

■ The use of thrombolysis is significantly lower inBlack patients than in White patients presenting withfirst acute myocardial infarction in the US, accordingto US-based researchers. Overall, they found that of498 such patients (mean age 66 years), Blacks weresignificantly less likely to receive thrombolysis and β-blockers, but significantly more likely to receivecalcium antagonists, than Whites. 319 (64%) of the498 patients were eligible to receive thrombolysisbased on electrocardiographic presentation, althoughonly 227 (71%) of these patients receivedthrombolysis. Again, eligible Blacks were considerablyless likely to receive thrombolysis than eligible Whites,‘despite similar eligibility by electrocardiography inboth races’, comment the researchers. Even in thegroup of patients ineligible for thrombolysis, ‘whiteswere twice as likely as blacks to get treated’, they add.Manhapra A, et al. Electrocardiographic presentation of blacks with firstmyocardial infarction does not explain race differences in thrombolysisadministration. American Heart Journal 140: 200-205, Aug 2000 800844091

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PharmacoEconomics & Outcomes News 9 Sep 2000 No. 2791173-5503/10/0279-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved