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Review Article N-Acetylcysteine Use to Prevent Contrast Medium–induced Nephropathy: Premature Phase III Trials .............................................................. 309 David A. Stenstrom, Leslie L. Muldoon, Hector Armijo-Medina, Suzanne Watnick, Nancy D. Doolittle, John A. Kaufman, Darryl R. Peterson, Joseph Bubalo, and Edward A. Neuwelt Clinical Studies Long-term Outcome of Uterine Artery Embolization for Symptomatic Uterine Leiomyomas ................................................................. 319 Paul N.M. Lohle, Marianne J. Voogt, Jolanda De Vries, Albert J. Smeets, Harry A.M. Vervest, Leo E.H. Lampmann, and Peter F. Boekkooi UAE in women with symptomatic leiomyomas leads to long-term symptom improvement. Predictors of failure were a lack of improvement in bleeding or pain at 1 year and the percent reduction in dominant tumor volume. Massive Abdominal Wall Hemorrhage from Injury to the Inferior Epigastric Artery: A Retrospective Review ....................................................... 327 Paul R. Sobkin, Allan I. Bloom, Mark W. Wilson, Jeanne M. LaBerge, Geoff S. Hastings, Roy L. Gordon, Lynn A. Brody, Rajiv Sawhney, and Robert K. Kerlan, Jr IEAI is most often an iatrogenic injury in a coagulopathic patient. Contrast medium– enhanced CT can be diagnostic for active bleeding, but in the setting of ongoing hemorrhage a negative study result should not preclude arteriography. Embolization is an effective means to control hemorrhage. Iodized Oil Accumulation in Hypervascular Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization: Comparison of Imaging Findings with CT during Hepatic Arteriography ................................................. 333 Takeshi Fujita, Katsuyoshi Ito, Masahiro Tanabe, Shigenari Yamatogi, Hideko Sasai, and Naofumi Matsunaga Although iodized oil accumulation in hypervascular HCCs correlates with the degree of lesion enhancement on CT/HA in most cases, a discrepancy may occur in a substantial number of cases, which likely affects the prediction of therapeutic effects in hypervascular HCCs. JVIR Journal of Vascular and Interventional Radiology Volume 19 Number 3 March 2008

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� Review Article

N-Acetylcysteine Use to Prevent Contrast Medium–induced Nephropathy: PrematurePhase III Trials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309

David A. Stenstrom, Leslie L. Muldoon, Hector Armijo-Medina, Suzanne Watnick,Nancy D. Doolittle, John A. Kaufman, Darryl R. Peterson, Joseph Bubalo, andEdward A. Neuwelt

� Clinical Studies

Long-term Outcome of Uterine Artery Embolization for Symptomatic UterineLeiomyomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319

Paul N.M. Lohle, Marianne J. Voogt, Jolanda De Vries, Albert J. Smeets,Harry A.M. Vervest, Leo E.H. Lampmann, and Peter F. Boekkooi

UAE in women with symptomatic leiomyomas leads to long-term symptom improvement.Predictors of failure were a lack of improvement in bleeding or pain at 1 year and thepercent reduction in dominant tumor volume.

Massive Abdominal Wall Hemorrhage from Injury to the Inferior Epigastric Artery:A Retrospective Review . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 327

Paul R. Sobkin, Allan I. Bloom, Mark W. Wilson, Jeanne M. LaBerge, Geoff S. Hastings,Roy L. Gordon, Lynn A. Brody, Rajiv Sawhney, and Robert K. Kerlan, Jr

IEAI is most often an iatrogenic injury in a coagulopathic patient. Contrastmedium– enhanced CT can be diagnostic for active bleeding, but in the setting of ongoinghemorrhage a negative study result should not preclude arteriography. Embolization is aneffective means to control hemorrhage.

Iodized Oil Accumulation in Hypervascular Hepatocellular Carcinoma afterTranscatheter Arterial Chemoembolization: Comparison of Imaging Findings with CTduring Hepatic Arteriography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 333

Takeshi Fujita, Katsuyoshi Ito, Masahiro Tanabe, Shigenari Yamatogi, Hideko Sasai, andNaofumi Matsunaga

Although iodized oil accumulation in hypervascular HCCs correlates with the degree oflesion enhancement on CT/HA in most cases, a discrepancy may occur in a substantialnumber of cases, which likely affects the prediction of therapeutic effects in hypervascularHCCs.

JVIRJournal of Vascular and Interventional Radiology

Volume 19

Number 3

March 2008

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Ionic Versus Nonionic Contrast Media Solvents Used with an Epirubicin-based Agent forTransarterial Chemoembolization of Hepatocellular Carcinoma. . . . . . . . . . . . . . . . . . . . 342

Wen-Sheng Tzeng, Reng-Hong Wu, Shih-Chin Chang, Chung-Kuao Chou, Ching-Yih Lin,Jyh-Jou Chen, Shun-Chun Yang, and Chi-Hung Lin

Epirubicin–iodized oil emulsions prepared with nonionic contrast medium are more stableand are associated with lower tumor grade in patients with inoperable HCC. The choice ofsolvent, however, does not appear to have an effect on patient survival.

Transjugular Liver Biopsy: A Retrospective Analysis of 601 Cases . . . . . . . . . . . . . . . . . . 351

Thomas Mammen, Shyamkumar N. Keshava, C.E. Eapen, Lakshminarayan Raghuram,Vinu Moses, Kota Gopi, Narayanam Surendra Babu, Jeyamani Ramachandran, andGeorge Kurien

With technical modifications such as transcaval liver biopsy and with access to US in theangiography suite, interventionalist can achieve higher technical success rates for thisprocedure. The authors’ institutional experience with this procedure reiterates its highhistopathologic positivity and safety profile both in adult and pediatric patients.

Cavoatrial Junction and Central Venous Anatomy: Implications for Central VenousAccess Tip Position . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359

Kevin M. Baskin, Rafael M. Jimenez, Anne Marie Cahill, Abass F. Jawad, andRichard B. Towbin

A more accurate understanding of the superior vena cava anatomy is essential for thecorrect interpretation of central venous access device position. The true cavoatrial junctionis located more inferiorly than commonly believed and is not accurately estimated withcommonly used imaging landmarks. A point two vertebral body units below the carinaenables the reliable estimate of the position of the cavoatrial junction. Catheter tip positioncan be most reliably described in vertebral body units below the carina, with use of thethoracic spine as an internal ruler.

Compression of the Left Common Iliac Vein in Asymptomatic Subjects and Patients withLeft Iliofemoral Deep Vein Thrombosis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366

Levent Oguzkurt, Ugur Ozkan, Serife Ulusan, Zafer Koc, and Fahri Tercan

There was considerable overlap between the degree of compression in patients with IVCS andcontrol subjects. Compression of the left common iliac vein was significantly more prominent inpatients with lower extremity deep vein thrombosis due to IVCS when compared with controlsubjects. Compression in excess of 70% as demonstrated at CT can be helpful for identifyingpossible underlying IVCS in patients with a left lower extremity deep vein thrombosis.

Catheter-directed Thrombolysis with the Endowave System in the Treatment of AcuteMassive Pulmonary Embolism: A Retrospective Multicenter Case Series . . . . . . . . . . . . . 372

Abbas Chamsuddin, Lama Nazzal, Brandon Kang, Irwin Best, Gail Peters, Sepehr Panah,Louis Martin, Curtis Lewis, Chadi Zeinati, John W. Ho, and Anthony C. Venbrux

US-assisted catheter-directed thrombolysis is an effective method for treating massive thrombolysis. Ithas the potential to shorten the time of lysis and lower the dose of thrombolytics.

Contents, continued — Volume 19 � Number 3 � March 2008

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Clinical and Economic Evaluation of the Trellis-8 Infusion Catheter for Deep VeinThrombosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377

Daniel E. Hilleman and Mahmood K. Razavi

Thrombolysis in DVT with the TIC is associated with a greater technical success rate, alower rate of bleeding, and a lower cost than that reported for CDT. These preliminaryresults indicate that further evaluation of the TIC in the treatment of DVT is warranted.

Retrievable versus Permanent Caval Filter Procedures: When Are They Cost-effective forInterventional Radiology? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384

Bertrand Janne d’Othee, Salomao Faintuch, Allen W. Reedy, Carl F. Nickerson, andMax P. Rosen

The preferential use of retrievable versus permanent devices for filter placement isfinancially advantageous for an IR unit only if at least 41% of them are eventually removed.The use of clinical criteria to select device type allows significant cost savings.

A Comparison of Clinical Outcomes with Retrievable and Permanent InferiorVena Cava Filters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393

Hyun S. Kim, Mark J. Young, Anand K. Narayan, Kelvin Hong, Robert P. Liddell, andMichael B. Streiff

In this retrospective cohort study, RFs and PFs provided similar protection from PE withcomparable complication rates. Clinicians should select an IVC filter based on theprojected duration of filtration needed at the time of placement rather than filter type.

Comparison of Physician-rated Performance Characteristics of Hydrophilic-coatedGuide Wires . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400

Anand Shah, Charles Lau, S. William Stavropoulos, Alexander Nemeth,Michael C. Soulen, Jeffrey A. Solomon, Jeffrey I. Mondschein, Aalpen A. Patel,Richard D. Shlansky-Goldberg, Maxim Itkin, Jesse L. Chittams, and Scott O. Trerotola

In addition to the highest-rated overall balance of properties, the Glidewire hadsignificantly higher-rated lubricity and radiopacity characteristics compared with theZIPwire.

Liquid 188Re-filled Balloon Dilation for the Treatment of Refractory Benign AirwayStrictures: Preliminary Experience . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406

Jin Hyoung Kim, Ji Hoon Shin, Ho-Young Song, Tae Sun Shim, Yeon-Mok Oh,Seung Jun Oh, and Dae Hyuk Moon

� irradiation with liquid 188Re-filled balloon dilation can be safely used for refractorybenign airway strictures. A large study with longer follow-up is needed to draw a definiteconclusion.

Contents, continued — Volume 19 � Number 3 � March 2008

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Immediate Renal Tumor Involution after Radiofrequency Thermal Ablation . . . . . . . . . 412

Suvranu Ganguli, Darren D. Brennan, Salomao Faintuch, Mostafa E. Rayan, andS. Nahum Goldberg

Renal tumors decrease in size immediately after treatment with RF thermal ablation.Immediate tumor involution after RF ablation should be anticipated and follow-up imagingstudies should ideally be compared to a baseline tumor size measured as soon as possibleafter ablation.

Radiofrequency Ablation in Combination with Osteoplasty in the Treatment of PainfulMetastatic Bone Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419

Ralf Thorsten Hoffmann, Tobias F. Jakobs, Christoph Trumm, Christof Weber,Thomas K. Helmberger, and Maximilian F. Reiser

RF ablation and osteoplasty can be combined within one session and is both feasible anduseful for the treatment of osteolytic bone metastases with regard to pain relief.

� Laboratory Investigation

Efficacy of a Polyphosphazene Nanocoat in Reducing Thrombogenicity, In-stent Stenosis,and Inflammatory Response in Porcine Renal and Iliac Artery Stents . . . . . . . . . . . . . . . 427

Christina Henn, Stefanie Satzl, Patricia Christoph, Patrick Kurz, Boris Radeleff,Ulrike Stampfl, Sibylle Stampfl, Irina Berger, and Goetz Martin Richter

PTFEP-coated stents exhibited reduced thrombus deposition and a trend toward less in-stent stenosis and inflammatory response than bare metal stents.

� Brief Reports

Right Renal Artery In Vivo Stent Fracture . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439

Scott W. Robertson, David B. Jessup, Isabel J. Boero, and Christopher P. Cheng

Postembolization Syndrome: Changes in White Blood Cell Counts Immediately afterUterine Artery Embolization. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443

Suvranu Ganguli, Salomao Faintuch, Gloria M. Salazar, and Dmitry J. Rabkin

In Vivo Positive Contrast IRON Sequence and Quantitative T2* Measurement ConfirmsInflammatory Burden in a Patient with Asymptomatic Carotid Atheroma after USPIO-enhanced MR Imaging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 446

Simon P.S. Howarth, Zhi-Yong Li, Tjun Y. Tang, Martin J. Graves, Jean M. U-King-Im,and and Jonathan H. Gillard

Contents, continued — Volume 19 � Number 3 � March 2008

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Management of Severe Vena Cava Filter Tilting: Experience with Bard G-2 Filters . . . . 449

Ulku C. Turba, Craig Glaiberman, Daniel Picus, Bulent Arslan, John F. Angle, andAlan H. Matsumoto

Radiofrequency Ablation as Salvage Therapy for Unresectable Locally RecurrentRectal Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 454

Sari H. Green, Vijay P. Khatri, and John P. McGahan

� Letters to the Editor

Amplatzer-Onyx Sandwich: A Method for Impermeable Proximal CerebralVessel Occlusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459

Clemens M. Schirmer, Daniel A. Hoit, and Adel M. Malek

Delayed Rupture of the External Iliac Artery after Balloon Angioplasty andStent Placement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460

Goncalo Sobrinho and Jose P. Albino

Radiofrequency Ablation of Functioning Lung Metastases from ParathyroidCarcinoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462

Toshihiro Iguchi, Kotaro Yasui, Takao Hiraki, Hideo Gobara, Hidefumi Mimura,Shuhei Sato, Hiroyasu Fujiwara, Ai Yano, Hiroyoshi Doihara, and Susumu Kanazawa

� Departments

Abstracts of Current Literature . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 465

Advertisers’ Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A4

Business Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A16

Classified Services . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A27

Forthcoming Articles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .A18

Publication Information for Authors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . www.jvir.org

Contents, continued — Volume 19 � Number 3 � March 2008