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VOLUME 81, NUMBER 4, APRIL 2013 Commentary Molecular Mechanisms of Urolithiasis 701 Will Green and Hari Ratan Journal Watch Commentary on: Tolvaptan in Patients With Autosomal-Dominant Polycystic Kidney Disease 705 Peter Black and Roger Sutton Review Article A Review of Contemporary Data on Surgically Resected Renal MassesBenign or Malignant? 707 Anthony T. Corcoran, Paul Russo, William T. Lowrance, Aviva Asnis-Alibozek, John A. Libertino, Daniel A. Pryma, Chaitanya R. Divgi, and Robert G. Uzzo Grand Rounds A 45-Year-Old With Neuroendocrine Carcinoma of the Prostate 714 Chad Reichard, Timothy Gilligan, Katherine E. Watts, Cristina Magi-Galluzzi, and Eric A. Klein Endourology and Stones Improving the Durability of Digital Flexible Ureteroscopes 717 Theocharis Karaolides, Christian Bach, Stefanos Kachrilas, Anuj Goyal, Junaid Masood, and Noor Buchholz Clinically Insignicant Residual Fragments: An Acceptable Term in the Computed Tomography Era? 723 Yasser Osman, Ahmed M. Harraz, Ahmed R. El-Nahas, Bassam Awad, Naser El-Tabey, Haytham Shebel, Ahmed M. Shoma, Ibrahim Eraky, and Mahmoud El-Kenawy Gemstone Spectral Imaging Dual-energy Computed Tomography: A Novel Technique to Determine Urinary Stone Composition 727 Xiaohu Li, Ren Zhao, Bin Liu, and Yongqiang Yu Effects of Aminobisphosphonates and Thiazides in Patients With Osteopenia/Osteoporosis, Hypercalciuria, and Recurring Renal Calcium Lithiasis 731 Miguel Angel Arrabal-Polo, Salvador Arias-Santiago, Tomas de Haro-Mun ~oz, Adriana Lopez-Ruiz, Jacinto Orgaz-Molina, Samuel Gonzalez-Torres, Armando Zuluaga- Gomez, and Miguel Arrabal-Martin Health Outcomes Research Clinical Outcomes of Sacral Neuromodulation in Patients With Neurologic Conditions 738 Kenneth M. Peters, Pridvi Kandagatla, Kim A. Killinger, Cheryl Wolfert, and Judith A. Boura EDITORIAL COMMENT: Ernst S. C. van Waalwijk van Doorn 743 REPLY: Kenneth M. Peters, Judith A. Boura, Pridvi Kandagatla, Kim A. Killinger, and Cheryl Wolfert 744 Factors Associated With Reduction in Use of Neoadjuvant Androgen Suppression Therapy Before Radical Prostatectomy 745 Matthew J. OShaughnessy, Stephanie L. Jarosek, Beth A. Virnig, Badrinath R. Konety, and Sean P. Elliott EDITORIAL COMMENT: Florian R. Schroeck and Ted A. Skolarus 750 Infectious Diseases Causative Pathogens, Antibiotic Sensitivity, Resistance Patterns, and Severity in a Contemporary Series of Fourniers Gangrene 752 Marc A. Bjurlin, Thomas OGrady, Dae Y. Kim, Naveen Divakaruni, Andrew Drago, Jennifer Blumetti, and Courtney M. P. Hollowell EDITORIAL COMMENT: Gilbert Wise 758 REPLY: Marc A. Bjurlin, Thomas OGrady, Courtney M. P. Hollowell, and Dae Y. Kim 758 continued on page A8 Cover Photo: Molecular Mechanisms of UrolithiasisWill Green and Hari Ratan (See page 701.) Full-text articles available online at www.goldjournal.net

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VOLUME 81, NUMBER 4, APRIL 2013

CommentaryMolecular Mechanisms of Urolithiasis 701Will Green and Hari Ratan

Journal WatchCommentary on: Tolvaptan in Patients WithAutosomal-Dominant Polycystic KidneyDisease 705Peter Black and Roger Sutton

Review ArticleA Review of Contemporary Data on SurgicallyResected Renal Masses—Benign orMalignant? 707Anthony T. Corcoran, Paul Russo, William T. Lowrance,Aviva Asnis-Alibozek, John A. Libertino, Daniel A. Pryma,Chaitanya R. Divgi, and Robert G. Uzzo

Grand RoundsA 45-Year-Old With Neuroendocrine Carcinomaof the Prostate 714Chad Reichard, Timothy Gilligan, Katherine E. Watts,Cristina Magi-Galluzzi, and Eric A. Klein

Endourology and StonesImproving the Durability of Digital FlexibleUreteroscopes 717Theocharis Karaolides, Christian Bach, Stefanos Kachrilas,Anuj Goyal, Junaid Masood, and Noor Buchholz

Clinically Insignificant Residual Fragments: AnAcceptable Term in the Computed TomographyEra? 723Yasser Osman, Ahmed M. Harraz, Ahmed R. El-Nahas,Bassam Awad, Naser El-Tabey, Haytham Shebel,Ahmed M. Shoma, Ibrahim Eraky, and Mahmoud El-Kenawy

Cover Photo: “Molecular Mechanisms of Urolithiasis” Will Green

Full-text articles available online at www.goldjournal.net

Gemstone Spectral Imaging Dual-energyComputed Tomography: A Novel Technique toDetermine Urinary Stone Composition 727Xiaohu Li, Ren Zhao, Bin Liu, and Yongqiang Yu

Effects of Aminobisphosphonates and Thiazides inPatients With Osteopenia/Osteoporosis,Hypercalciuria, and Recurring Renal CalciumLithiasis 731Miguel Angel Arrabal-Polo, Salvador Arias-Santiago,Tomas de Haro-Mun~oz, Adriana Lopez-Ruiz, JacintoOrgaz-Molina, Samuel Gonzalez-Torres, Armando Zuluaga-Gomez, and Miguel Arrabal-Martin

Health Outcomes ResearchClinical Outcomes of Sacral Neuromodulation inPatients With Neurologic Conditions 738Kenneth M. Peters, Pridvi Kandagatla, Kim A. Killinger,Cheryl Wolfert, and Judith A. Boura

EDITORIAL COMMENT: Ernst S. C. van Waalwijk vanDoorn 743REPLY: Kenneth M. Peters, Judith A. Boura,Pridvi Kandagatla, Kim A. Killinger, and Cheryl Wolfert 744

Factors Associated With Reduction in Use ofNeoadjuvant Androgen Suppression TherapyBefore Radical Prostatectomy 745Matthew J. O’Shaughnessy, Stephanie L. Jarosek,Beth A. Virnig, Badrinath R. Konety, and Sean P. Elliott

EDITORIAL COMMENT: Florian R. Schroeck andTed A. Skolarus 750

Infectious DiseasesCausative Pathogens, Antibiotic Sensitivity,Resistance Patterns, and Severity ina Contemporary Series of Fournier’sGangrene 752Marc A. Bjurlin, Thomas O’Grady, Dae Y. Kim,Naveen Divakaruni, Andrew Drago, Jennifer Blumetti, andCourtney M. P. Hollowell

EDITORIAL COMMENT: Gilbert Wise 758REPLY: Marc A. Bjurlin, Thomas O’Grady,Courtney M. P. Hollowell, and Dae Y. Kim 758

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and Hari Ratan (See page 701.)

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InfertilityPregnancy After Varicocelectomy: Impact ofPostoperative Motility and DFI 760Karen Baker, John McGill, Rakesh Sharma, Ashok Agarwal,and Edmund Sabanegh, Jr.

Laparoscopy and RoboticsFundamental Skills of Robotic Surgery: AMulti-institutional Randomized Controlled Trialfor Validation of a Simulation-basedCurriculum 767Andrew P. Stegemann, Kamran Ahmed, Johar R. Syed,Shabnam Rehman, Khurshid Ghani, Ricardo Autorino,Mohamed Sharif, Amrith Rao, Yi Shi, Gregory E. Wilding,James M. Hassett, Ashirwad Chowriappa,Thenkurussi Kesavadas, James O. Peabody, Mani Menon,Jihad Kaouk, and Khurshid Ahad Guru

RENAL Nephrometry Score Is Associated WithComplications After Renal Cryoablation: AMulticenter Analysis 775David M. Sisul, Michael A. Liss, Kerrin L. Palazzi,Kaitlan Briles, Reza Mehrazin, Robert E. Gold,James H. Masterson, Hossein S. Mirheydar, Ramzi Jabaji,Sean P. Stroup, James O. L’Esperance, Robert W. Wake,Gerant Rivera-Sanfeliz, and Ithaar H. Derweesh

A Prospective Study of Transition FromLaparoscopic to Robot-assisted RadicalProstatectomy: Quality of Life Outcomes After36-Month Follow-up 781Viktor Berge, Rolf E. Berg, Jon R. Hoff, Nicolai Wessel,Lien M. Diep, Steinar J. Karlsen, and Lars M. Eri

Impact of Robot-assisted RadicalProstatectomy on Lower Urinary TractSymptoms and Predictive Factors for SymptomChanges: A Longitudinal Study 787Jeong Hyun Kim, Yun-Sok Ha, Seong Jin Jeong,Dong-Hyeon Lee, Wun-Jae Kim, and Isaac Yi Kim

Male Sexual DysfunctionImprovement of Chronic Peyronie’s DiseaseSymptoms After Diabetic Compensation: ARetrospective Study 794Giorgio Cavallini and Gianni Paulis

Topical Anesthetic Agents for PrematureEjaculation: A Systematic Review andMeta-analysis 799Chunxiao Pu, Lu Yang, Liangren Liu, Haichao Yuan,Qiang Wei, and Ping Han

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OncologyDoes Timing of Cytoreductive NephrectomyImpact Patient Survival With MetastaticRenal Cell Carcinoma in the TyrosineKinase Inhibitor Era? A Multi-institutionalStudy 805Sean P. Stroup, Omer A. Raheem, Kerrin L. Palazzi,Michael A. Liss, Reza Mehrazin, Ryan P. Kopp,Nishant Patel, Seth A. Cohen, Samuel K. Park,Anthony L. Patterson, Christopher J. Kane,Frederick Millard, and Ithaar H. Derweesh

EDITORIAL COMMENT: Raoul R. Salup 811

REPLY: Ithaar H. Derweesh, Sean P. Stroup, andFrederick Millard 812

Management of Bladder Cancer After RenalTransplantation 813Derek Prabharasuth, Kelvin A. Moses, Melanie Bernstein,Guido Dalbagni, and Harry W. Herr

Defining Good Candidates for ExtraperitonealCystectomy: Results From Random PeritoneumBiopsies of 136 Cases 820Yi-Ping Zhu, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang,Bo Dai, Yi-Jun Shen, and Chao-fu Wang

EDITORIAL COMMENT: Chandy Ellimoottil andMarcus L. Quek 824

REPLY: Yi-Ping Zhu and Ding-Wei Ye 825

Does Positive Family History of ProstateCancer Increase the Risk of Prostate Cancer onInitial Prostate Biopsy? 826Ahmed Elshafei, Ayman Salah Moussa, Asmaa Hatem,Vargo Ethan, Kamol Panumatrassamee,Adrian V. Hernandez, and J. Stephen Jones

EDITORIAL COMMENT: Christian Thomas 830REPLY: Ahmed Elshafei and J. Stephen Jones 830

Increased Incidence of PathologicallyNonorgan Confined Prostate Cancer in African-American Men Eligible for ActiveSurveillance 831Yun-Sok Ha, Amirali Salmasi, Michael Karellas,Eric A. Singer, Jeong Hyun Kim, Misop Han, Alan W. Partin,Wun-Jae Kim, Dong Hyeon Lee, and Isaac Yi Kim

EDITORIAL COMMENT: Bishoy A. Gayed andVitaly Margulis 835REPLY: Isaac Yi Kim 835

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UROLOGY 81 (4), 2013

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Potential Consequences of Low Biopsy CoreNumber in Selection of Patients With ProstateCancer for Current Active SurveillanceProtocols 837Georg M€uller, Gernot Bonkat, Malte Rieken,Stephen F. Wyler, Lukas Bubendorf, Heike P€uschel,Thomas C. Gasser, Alexander Bachmann, andCyrill A. Rentsch

EDITORIAL COMMENT: Sean Michael Collins 842REPLY: Georg M€uller, Alexander Bachmann, andCyrill A. Rentsch 843

Prostatic Diseases and Male VoidingDysfunctionDoes Prostate Morphology Affect OutcomesAfter Holmium Laser Enucleation? 844Eric Smith Wisenbaugh, Rafael Nunez-Nateras,Chinedu O. Mmeje, Jonathan N. Warner, andMitchell R. Humphreys

Prostate-specific Antigen Density: A BetterIndex of Obesity-related PSA Decrease inOstensibly Healthy Korean Men With a PSA<3.0 ng/mL 849Jae Heon Kim, Seung Whan Doo, Won Jae Yang,Yun Seob Song, and Soon-Sun Kwon

EDITORIAL COMMENT: Gerald W. Chodak 852REPLY: Won Jae Yang 852

GreenLight XPS 180W vs HPS 120W LaserTherapy for Benign Prostate Hyperplasia: AProspective Comparative Analysis After 200Cases in a Single-center Study 853Tal Ben-Zvi, Pierre-Alain Hueber, Daniel Liberman,Roger Valdivieso, and Kevin C. Zorn

Intravesical Prostatic Protrusion Can Bea Predicting Factor for the Treatment Outcomein Patients With Lower Urinary Tract SymptomsDue to Benign Prostatic Obstruction TreatedWith Tamsulosin 859Alin Adrian Cumpanas, Mircea Botoca, Radu Minciu, andViorel Bucuras

Pediatric UrologyCollective Circumcision Performed in Sudan:Evaluation in Terms of Early Complications andAlternative Practice 864Deniz Arslan, Mehmet Kalkan, Hamza Yazgan,Ulviye €Un€uvar, and Coskun Sahin

EDITORIAL COMMENT: Catherine R. deVries 867REPLY: Mehmet Kalkan, Coskun Sahin, andHamza Yazgan 868

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High-risk Human Papilloma Virus Infection ofthe Foreskin in Asymptomatic Boys 869Michela de Martino, Andrea Haitel, Fritz Wrba,Georg Schatzl, Tobias Klatte, and Matthias Waldert

Factors Indicating Renal Injury in PediatricBilateral Ureteropelvic-junctionObstruction 873Yong Seung Lee, Hyeon Joo Jeong, Young Jae Im, Myung-Joon Kim, Mi-Jung Lee, Mijin Yun, and Sang Won Han

EDITORIAL COMMENT: Edmond T. Gonzales, Jr. 878REPLY: Yong Seung Lee, Hyeyoung Lee, Young Jae Im, andSang Won Han 879

Kidney Stone Size and Hounsfield Units PredictSuccessful Shockwave Lithotripsy inChildren 880Ahmed El-Assmy, Ahmed R. El-Nahas, Mohamed E. Abou-El-Ghar, Bassam A. Awad, and Khaled Z. Sheir

Pediatric Case ReportsAdolescent XanthogranulomatousPyelonephritis Mimicking Renal Cell Carcinomaon Urine Cytology: An AtypicalPresentation 885Brian M. Inouye, George Chiang, Robert O. Newbury, andNicholas Holmes

Malignant Urothelial Carcinoma of UrinaryBladder in a Young Child: A Rare CaseReport 888Sujoy Neogi, Piaray Lal Kariholu, Gaurav Dhakre,Vishal Gupta, Neema Agarwal, and Punam Bhadani

Reconstructive UrologyThe Impact of Ventral Oral Graft BulbarUrethroplasty on Sexual Life 891Enzo Palminteri, Elisa Berdondini, Cosimo De Nunzio,Giorgio Bozzini, Serena Maruccia, Cesare Scoffone, andLuca Carmignani

EDITORIAL COMMENT: Richard A. Santucci 898REPLY: Enzo Palminteri 898

Combining Ventral Buccal Mucosal Graft Onlayand Dorsal Full Thickness Skin Graft InlayDecreases Failure Rates in Long BulbarStrictures (‡6 cm) 899Mang L. Chen, Brian D. Odom, Lewis J. Johnson, andRichard A. Santucci

EDITORIAL COMMENT: Reynaldo G. Gomez 902

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UROLOGY 81 (4), 2013

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Surgical Techniques in UrologyHook Wire Localization for Testis SparingSurgery 904Teng Aik Ong, Nur Adura Yaakup,Sivaprakasam Sivalingam, and Azad Hassan Razack

EDITORIAL COMMENT: Edmund Sabanegh, Jr. 907REPLY: Teng Aik Ong and Azad Hassan Razack 907

Manual Repositioning of Intra-atrial KidneyCancer Tumor Thrombus: A TechniqueReducing the Need for CardiopulmonaryBypass 909Meike Schneider, Boris Hadaschik, Peter Hallscheidt,Hildegard Jakobi, Markus Fritz, Johann Motsch,Sascha Pahernik, and Markus Hohenfellner

EDITORIAL COMMENT: Venkatesh Krishnamurthi 914

Technology and EngineeringImpact of Bent Distortion on Accuracy ofMeasurement During TransrectalUltrasonography for Prostatic Imaging: APreliminary Study 915Hyung Ho Lee, Joo Yong Lee, Ho Song Yu,Richilda Red Diaz, Won Sik Ham, Koon Ho Rha,Young Deuk Choi, and Kang Su Cho

Basic and Translational ScienceAbstractsFesoterodine, Its Active Metabolite, and

Tolterodine Bind Selectively to MuscarinicReceptors in Human Bladder Mucosa andDetrusor Muscle 920Akira Yoshida, Yusuke Fuchihata, Shiori Kuraoka,Ayaka Osano, Atsushi Otsuka, Seiichiro Ozono,Masayuki Takeda, Keisuke Masuyama, Isao Araki, andShizuo Yamada

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Fiber-substituted Conditionally ReplicatingAdenovirus Ad5F35 Induces Oncolysis ofHuman Bladder Cancer Cells in In VitroAnalysis 920Akinobu Gotoh, Hisao Nagaya, Takeshi Kanno,Masatoshi Tagawa, and Tomoyuki Nishizaki

Ejaculatory Responses are Inhibited bya New Chemical Entity, DA-8031, in PreclinicalRodent Models of Ejaculation 920Kyung Koo Kang, Gook Jun Ahn, Ji Hyun Sung,Soon Hoe Kim, Hyunah Kim, and Sukhyang Lee

Effect of Microbubble-enhanced Ultrasoundon Prostate Permeability: A PotentialTherapeutic Method for ProstateDisease 921Yongliang Liu, Shanhong Yi, Jinlong Zhang,Zhenqiang Fang, Feng Zhou, Weisheng Jia, Zheng Liu, andGang Ye

Images in Clinical UrologyUrethral Injury by an Orthopedic Screw: AnUnusual Cause of Hematuria e25Laura M. Martinez, Kevin Kierl, and Gennady Slobodov

Localized Perirenal RetroperitonealFibrosis e27Chandy Ellimoottil, Spencer Hart, Vikas Mehta, andMarcus L. Quek

Cystinuria Crystals: An Image From a 14-Year-Old Girl With Cystinuria e29Franklin Lee, Ruthie Su, and Thomas Lendvay

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UROLOGY 81 (4), 2013