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The Spectrum of Renal Bone Disease Meryl S. LeBoff, MD Guest Editor TABLE OF CONTENTS 95 The Spectrum of Renal Bone Disease: Introduction Meryl S. LeBoff 97 Chronic Kidney Disease/Bone and Mineral Metabolism: The Imperfect Storm Mark E. Williams 105 Kidney Disease Outcomes Quality Initiative Guidelines for Bone and Mineral Metabolism: Emerging Questions Tejas V. Patel and Ajay K. Singh 113 Role of Vitamin D in Chronic Kidney Disease Tejas V. Patel and Ajay K. Singh 122 Bone Histomorphometry in Renal Osteodystrophy Susan M. Ott 133 A Structural Approach to Skeletal Fragility in Chronic Kidney Disease Mary B. Leonard 144 Diagnosis and Treatment of Osteoporosis in Chronic Renal Disease Paul D. Miller 156 The Pathogenesis of Vascular Calcification in the Chronic Kidney Disease Mineral Bone Disorder: The Links Between Bone and the Vasculature Keith A. Hruska, Suresh Mathew, Richard J. Lund, Imran Memon, and Georges Saab 166 Bone Disease in Kidney Transplant Patients Minna Huang and Stuart M. Sprague On the Cover: Bone biopsies showing adynamic bone disease with low bone formation (top) compared with osteitis fibrosa with extensive formation and resorption (bottom). Photos by Susan Ott. (See article by Susan Ott, p. 122.) Figures in column from the American Journal of Kidney Diseases Atlas of Renal Pathology. Courtesy of Agnes B. Fogo, MD and the National Kidney Foundation. VOL. 29, NO. 2 MARCH 2009

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The Spectrum of Renal Bone DiseaseMeryl S. LeBoff, MD

Guest Editor

TABLE OF CONTENTS

95 The Spectrum of Renal Bone Disease: IntroductionMeryl S. LeBoff

97 Chronic Kidney Disease/Bone and Mineral Metabolism: TheImperfect Storm

Mark E. Williams

105 Kidney Disease Outcomes Quality Initiative Guidelines forBone and Mineral Metabolism: Emerging Questions

Tejas V. Patel and Ajay K. Singh

113 Role of Vitamin D in Chronic Kidney DiseaseTejas V. Patel and Ajay K. Singh

122 Bone Histomorphometry in Renal OsteodystrophySusan M. Ott

133 A Structural Approach to Skeletal Fragility in Chronic KidneyDisease

Mary B. Leonard

144 Diagnosis and Treatment of Osteoporosis in Chronic RenalDisease

Paul D. Miller

156 The Pathogenesis of Vascular Calcification in the ChronicKidney Disease Mineral Bone Disorder: The Links BetweenBone and the Vasculature

Keith A. Hruska, Suresh Mathew, Richard J. Lund, Imran Memon,and Georges Saab

166 Bone Disease in Kidney Transplant PatientsMinna Huang and Stuart M. Sprague

On the Cover: Bone biopsies showing adynamic bone disease with low boneformation (top) compared with osteitis fibrosa with extensive formation andresorption (bottom). Photos by Susan Ott. (See article by Susan Ott, p. 122.)

Figures in column from the American Journal of Kidney Diseases Atlas of RenalPathology. Courtesy of Agnes B. Fogo, MD and the National Kidney Foundation.

VOL. 29, NO. 2 MARCH 2009

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