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Regulatory Toxicology and Pharmacology CONTENTS Volume 67, Issue 2, Supplement 1, 1 November 2013 FOREWORD S1 Assessing the mammalian toxicity of high-boiling point petroleum substances Paul I. Feder, Richard C. Hertzberg SUPPLEMENT ARTICLES S4 Assessing the mammalian toxicity of high-boiling petroleum substances under the rubric of the HPV program Thomas M. Gray, Barry J. Simpson, Mark J. Nicolich, F. Jay Murray, Allen W. Verstuyft, Randy N. Roth, Richard H. McKee S10 The development of statistical models to determine the relationship between aromatic-ring class profile and repeat-dose and developmental toxicities of high-boiling petroleum substances Mark J. Nicolich, Barry J. Simpson, F. Jay Murray, Randy N. Roth, Thomas M. Gray S30 The relationship between repeat-dose toxicity and aromatic-ring class profile of high-boiling petroleum substances Randy N. Roth, Barry J. Simpson, Mark J. Nicolich, F. Jay Murray, Thomas M. Gray S46 The relationship between developmental toxicity and aromatic-ring class profile of high-boiling petroleum substances F. Jay Murray, Randy N. Roth, Mark J. Nicolich, Thomas M. Gray, Barry J. Simpson S60 Evaluating the male and female reproductive toxicity of high-boiling petroleum substances F. Jay Murray, Thomas M. Gray, Linda G. Roberts, Randy N. Roth, Mark J. Nicolich, Barry J. Simpson S75 Genetic toxicity of high-boiling petroleum substances Richard H. McKee, Ceinwen A. Schreiner, Mark J. Nicolich, Thomas M. Gray S86 Peer consultation on relationship between PAC profile and toxicity of petroleum substances Jacqueline Patterson, Andrew Maier, Melissa Kohrman-Vincent, Michael L. Dourson For a full and complete Guide for Authors, please go to: http://www.elsevier.com/locate/yrtph Abstracted/indexed in: EMBASE, EMBiology. Also covered in the abstract and citation database Scopus Ò . Full text available on ScienceDirect Ò .

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Page 1: Table of Contents

Regulatory Toxicology and Pharmacology

CONTENTS Volume 67, Issue 2, Supplement 1, 1 November 2013

FOREWORD

S1 Assessing the mammalian toxicity of high-boiling point petroleum substancesPaul I. Feder, Richard C. Hertzberg

SUPPLEMENT ARTICLES

S4 Assessing the mammalian toxicity of high-boiling petroleum substances under the rubric of the HPV programThomas M. Gray, Barry J. Simpson, Mark J. Nicolich, F. Jay Murray, Allen W. Verstuyft, Randy N. Roth, Richard H. McKee

S10 The development of statistical models to determine the relationship between aromatic-ring class profile and repeat-doseand developmental toxicities of high-boiling petroleum substances

Mark J. Nicolich, Barry J. Simpson, F. Jay Murray, Randy N. Roth, Thomas M. Gray

S30 The relationship between repeat-dose toxicity and aromatic-ring class profile of high-boiling petroleum substancesRandy N. Roth, Barry J. Simpson, Mark J. Nicolich, F. Jay Murray, Thomas M. Gray

S46 The relationship between developmental toxicity and aromatic-ring class profile of high-boiling petroleum substancesF. Jay Murray, Randy N. Roth, Mark J. Nicolich, Thomas M. Gray, Barry J. Simpson

S60 Evaluating the male and female reproductive toxicity of high-boiling petroleum substancesF. Jay Murray, Thomas M. Gray, Linda G. Roberts, Randy N. Roth, Mark J. Nicolich, Barry J. Simpson

S75 Genetic toxicity of high-boiling petroleum substancesRichard H. McKee, Ceinwen A. Schreiner, Mark J. Nicolich, Thomas M. Gray

S86 Peer consultation on relationship between PAC profile and toxicity of petroleum substancesJacqueline Patterson, Andrew Maier, Melissa Kohrman-Vincent, Michael L. Dourson

For a full and complete Guide for Authors, please go to: http://www.elsevier.com/locate/yrtph

Abstracted/indexed in: EMBASE, EMBiology. Also covered in the abstract and citation database Scopus�. Full text availableon ScienceDirect�.