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185 A Mirror OF THE PRACTICE OF MEDICINE AND SURGERY IN THE HOSPITALS OF LONDON. Nulla est alia pro certo noscendi via, nisi quam plurimas et morborum et dissectionum historias, tam aliorum proprias, collectas habere et inter se comparare.—MORGAGNI. De Sed. et Caus. Morb. lib. 14. Proœmium. ST. GEORGE’S HOSPITAL. Symptoms of Stone; no Calculus in the Bladder. (Under the care of Mr. CUTLER.) THE symptoms of stone in the bladder are so accurately described in most works on surgery, that the diagnosis of this complaint cannot be looked upon as difficult; still the whole train of signs accompanying the presence of a calculus may be evident, and yet, as these signs may be connected with other conditions of the bladder, we are not justified in pronouncing i upon the case, except the stone has been felt and heard. This I is a most excellent rule, and the following case will show how cautious surgeons should be in instances of this kind. The details were noted down by Mr. Holmes, surgical registrar to the hospital. Charles P-, eleven years old, was admitted, Nov. 9, 1853. This boy presented many of the symptoms of stone in the bladder : he had suffered for a year with frequent calls to pass urine, which fluid sometimes stopped suddenly while he was evacuating the bladder. Blood hjjd occasionally been passed with the urine, the symptoms were aggravated by exercise, and he had at such times pain in the course of the urethra. The urine was alkaline and very thick, from the presence of pus, the prepuce long, and the patient pale and thin. He suffered extremely from frequent and painful micturition, and could not abstain for longer than ten minutes. Mr. Cutler ordered a draught of infusion of buchu, with dilute nitro-muriatic acid, and tincture of columbo, three times a day, and morphia at night. No instrument was passed for the investigation of the state of the bladder, Mr. Cutler pre- ferring to wait until the irritation had a little subsided. In about a fortnight the parts were much less sensitive. On then passing a sound, the bladder was found to be rough and much contracted, but no stone could be felt. The same treatment was then pursued, ten drops of laudanum being added to the draught; but the symptoms referable to. the bladder were not materially alleviated, excepb that the boy was enabled for a time to retain his urine for about half an hour. Early in the following month a fluctuating swelling was noticed in the right iliac fossa, the formation of which did not seem to be attended with any marked symptoms. It gradually came forward, and presented a little way above Poupart’s ligament, near the anterior superior spine of the ileum. The poor boy became gradually weaker and much emaciated, on which account wine and good diet were ordered for him. The abscess was not interfered with, and burst in about ten days; after this the patient sank rapidly, and died on the 26th of December, seven weeks after admission. Post-mortem examination. Body greatly emaciated; a rounded ulcer opened, just under Poupart’s ligament on the right side, into a large sac. The abdominal cavity con- tained much purulent fluid, with recent yellow fibrine, and the intestines were in places adherent to each other and to the bladder. On passing a probe, and examining the opening in the integuments before spoken of, the instrument passed into a large abscess, occupying a considerable portion of the right psoas and iliacus muscles, but no diseased bone could anywhere be found, neither was it satisfactorily made out whence the ,abscess had taken its origin. The fat and areolar tissue around the base of the bladder were very indurated, and the bladder itself curiously divided by a horizontal septum into two cavities communicating by a small opening. The lining membrane was almost entirely gone, and the muscular parietes left bare and greatly fasciculated; in the posterior part of the upper cavity was a rounded opening formed by ulceration, which entirely pierced the walls of the organ, and had doubtless been occluded by intestine. The kidneys were much diseased; one of them was literally occupied through its whole area by scrofulous matter, except certain fibrous partitions dividing it into cavities. In the other kidney, ’which contained pus and calcareous matter in its pelvis, were one or two small collections of scrofulous deposit also. The ureters were not examined. The other organs presented nothing unusual. Epilepsy ; Death ; A utopsy. (Under the care of Dr. B. JONES.) Epilepsy is well known to have affected individuals without any material lesion of any point of the cerebro-spinal axis-a fact which has been frequently verified by post-mortem exa- minations ; but it is not rare, on the other hand, to find tumours, bony protrusions, softening, &c., as tangible causes of the epileptic attacks. Often is epilepsy seen in the surgical wards of hospitals, as the result of some lesion of the brain or spinal marrow, from a traumatic cause. The cases, however, in which the pathological changes which caused the fits can be clearly traced are not common, (for a very interesting one, see THE LANCET, vol. ii. 1853, p. 520;) we therefore beg to place the following one upon record, as noted by Dr. Barclay, the medical registrar of the hospital. Elizabeth S—, aged thirty-four years, was admitted, Dec. 21, 1853, under the care of Dr. Bence Jones. The patient is of diminutive size, anæmic-looking, ill-fed, and states that she has been suffering five or six months from fits of some sort, in which she was entirely unconscious. There was no evidence of her ever having bitten her tongue or injured herself; she could not tell whether she was convulsed, but had been told that she always tore her clothes when in a fit. Menstruation had been irregular for a long period, and entirely suppressed for twelve months. There was also leucorrhcea, combined with pruritus vulvæ, and the bowels were habitually confined. Some compound decoction of aloes was ordered; afterwards shower-baths twice a week, and steel wine. On the evening of the sixth day after admission, she was suddenly seized with fits of an epileptic character, which lasted throughcut the night, recurring at short intervals. She then sank into coma, and died. Post-mortem examination, (conducted by Dr. Ogle, curator of the museum to the hospital. )-The body was emaciated, and the hands livid. -Cranium: The bones of the skull were natural, as also the dura mater. The vessels of the arachnoid were very full, and the membrane itself, in places, opaque and thickened, containing several small, yellow deposits, of the size of millet-seeds. On the posterior part of the right hemisphere were three or four small masses of calcareous substance, intimately connected with the arachnoid. At a corresponding point on the left side-viz., at the lateral and posterior part—was a thickened mass of the same membrane, which at first sight had the appearance of a cyst. On examination, the following condition was observed:-Among the meshes of this thickened membrane a rather con- siderable amount of flllid existed, and continuous with the former was another membrane, lining a cavity composed of the surface of the cerebral convolutions, which at this place had apparently been subjected to considerable pressure. One of the convolutions was so diminished in size as to be reduced to a narrow band, as it were, which, like one or two of the sur- rounding convolutions which formed the floor of the cavity, was somewhat softened. The membrane lining the cyst was tolerably thick, and from its colour at nrst sight looked like brain matter; it could be entirely raised by the forceps, and on examination by the microscope was found to consist of a great number of vessels, with much granular matter, and some fibrillated structure mixed therewitli. The softened brain texture consisted of granular matter, with great numbers of oval, irregular nuclear cells, some wasted nerve tubes, and here and there accumulations of star-shaped and caudate bodies, with dark margins, and having a calcareous appearance. On section, the brain proved to be rather vascular, but of natural consistence generally; the ventricles were rather large, and contained two or three drachms of clear fluid, but were not distended. The arteries of the base of the brain were natural, and the other organs of the body did not offer any striking abnormal condition. ____ KING’S COLLEGE HOSPITAL. Cases of Epilepsy. (Under the care of Dr. TODD.) BEING on the subject of epilepsy, we shall just refer, in a few words, to some curious cases which were treated by Dr. Todd some time ago, and which presented features of some in- terest.

ST. GEORGE'S HOSPITAL

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185

A MirrorOF THE PRACTICE OF

MEDICINE AND SURGERYIN THE

HOSPITALS OF LONDON.

Nulla est alia pro certo noscendi via, nisi quam plurimas et morborumet dissectionum historias, tam aliorum proprias, collectas habere et interse comparare.—MORGAGNI. De Sed. et Caus. Morb. lib. 14. Proœmium.

ST. GEORGE’S HOSPITAL.

Symptoms of Stone; no Calculus in the Bladder.(Under the care of Mr. CUTLER.)

THE symptoms of stone in the bladder are so accuratelydescribed in most works on surgery, that the diagnosis of thiscomplaint cannot be looked upon as difficult; still the wholetrain of signs accompanying the presence of a calculus may beevident, and yet, as these signs may be connected with otherconditions of the bladder, we are not justified in pronouncing i

upon the case, except the stone has been felt and heard. This Iis a most excellent rule, and the following case will show howcautious surgeons should be in instances of this kind. Thedetails were noted down by Mr. Holmes, surgical registrar tothe hospital.

Charles P-, eleven years old, was admitted, Nov. 9,1853. This boy presented many of the symptoms of stone inthe bladder : he had suffered for a year with frequent calls topass urine, which fluid sometimes stopped suddenly while hewas evacuating the bladder. Blood hjjd occasionally beenpassed with the urine, the symptoms were aggravated byexercise, and he had at such times pain in the course of theurethra. The urine was alkaline and very thick, from thepresence of pus, the prepuce long, and the patient pale andthin. He suffered extremely from frequent and painfulmicturition, and could not abstain for longer than tenminutes.Mr. Cutler ordered a draught of infusion of buchu, with

dilute nitro-muriatic acid, and tincture of columbo, three timesa day, and morphia at night. No instrument was passed forthe investigation of the state of the bladder, Mr. Cutler pre-ferring to wait until the irritation had a little subsided. Inabout a fortnight the parts were much less sensitive. On then

passing a sound, the bladder was found to be rough and muchcontracted, but no stone could be felt.The same treatment was then pursued, ten drops of laudanum

being added to the draught; but the symptoms referable to.the bladder were not materially alleviated, excepb that theboy was enabled for a time to retain his urine for about halfan hour.

Early in the following month a fluctuating swelling wasnoticed in the right iliac fossa, the formation of which did notseem to be attended with any marked symptoms. It graduallycame forward, and presented a little way above Poupart’sligament, near the anterior superior spine of the ileum. The

poor boy became gradually weaker and much emaciated, onwhich account wine and good diet were ordered for him. Theabscess was not interfered with, and burst in about ten days;after this the patient sank rapidly, and died on the 26th ofDecember, seven weeks after admission.

Post-mortem examination. - Body greatly emaciated; a

rounded ulcer opened, just under Poupart’s ligament on theright side, into a large sac. The abdominal cavity con-tained much purulent fluid, with recent yellow fibrine, andthe intestines were in places adherent to each other and to thebladder. On passing a probe, and examining the opening inthe integuments before spoken of, the instrument passed intoa large abscess, occupying a considerable portion of the rightpsoas and iliacus muscles, but no diseased bone could anywherebe found, neither was it satisfactorily made out whence the,abscess had taken its origin. The fat and areolar tissue aroundthe base of the bladder were very indurated, and the bladderitself curiously divided by a horizontal septum into two cavitiescommunicating by a small opening. The lining membrane wasalmost entirely gone, and the muscular parietes left bare andgreatly fasciculated; in the posterior part of the upper cavitywas a rounded opening formed by ulceration, which entirelypierced the walls of the organ, and had doubtless been occludedby intestine. The kidneys were much diseased; one of themwas literally occupied through its whole area by scrofulousmatter, except certain fibrous partitions dividing it into

cavities. In the other kidney, ’which contained pus andcalcareous matter in its pelvis, were one or two small collectionsof scrofulous deposit also. The ureters were not examined.The other organs presented nothing unusual.

Epilepsy ; Death ; A utopsy.(Under the care of Dr. B. JONES.)

Epilepsy is well known to have affected individuals withoutany material lesion of any point of the cerebro-spinal axis-afact which has been frequently verified by post-mortem exa-minations ; but it is not rare, on the other hand, to findtumours, bony protrusions, softening, &c., as tangible causesof the epileptic attacks. Often is epilepsy seen in the surgicalwards of hospitals, as the result of some lesion of the brain orspinal marrow, from a traumatic cause. The cases, however,in which the pathological changes which caused the fits can beclearly traced are not common, (for a very interesting one, seeTHE LANCET, vol. ii. 1853, p. 520;) we therefore beg to placethe following one upon record, as noted by Dr. Barclay, themedical registrar of the hospital.

Elizabeth S—, aged thirty-four years, was admitted,Dec. 21, 1853, under the care of Dr. Bence Jones. The

patient is of diminutive size, anæmic-looking, ill-fed, andstates that she has been suffering five or six months from fitsof some sort, in which she was entirely unconscious. Therewas no evidence of her ever having bitten her tongue or injuredherself; she could not tell whether she was convulsed, but hadbeen told that she always tore her clothes when in a fit.Menstruation had been irregular for a long period, and entirelysuppressed for twelve months. There was also leucorrhcea,combined with pruritus vulvæ, and the bowels were habituallyconfined. Some compound decoction of aloes was ordered;afterwards shower-baths twice a week, and steel wine. Onthe evening of the sixth day after admission, she was suddenlyseized with fits of an epileptic character, which lastedthroughcut the night, recurring at short intervals. She thensank into coma, and died.Post-mortem examination, (conducted by Dr. Ogle, curator

of the museum to the hospital. )-The body was emaciated, andthe hands livid. -Cranium: The bones of the skull werenatural, as also the dura mater. The vessels of the arachnoidwere very full, and the membrane itself, in places, opaque andthickened, containing several small, yellow deposits, of thesize of millet-seeds. On the posterior part of the righthemisphere were three or four small masses of calcareoussubstance, intimately connected with the arachnoid. At a

corresponding point on the left side-viz., at the lateral andposterior part—was a thickened mass of the same membrane,which at first sight had the appearance of a cyst. Onexamination, the following condition was observed:-Amongthe meshes of this thickened membrane a rather con-

siderable amount of flllid existed, and continuous with theformer was another membrane, lining a cavity composed of thesurface of the cerebral convolutions, which at this place hadapparently been subjected to considerable pressure. One ofthe convolutions was so diminished in size as to be reduced toa narrow band, as it were, which, like one or two of the sur-rounding convolutions which formed the floor of the cavity,was somewhat softened. The membrane lining the cyst wastolerably thick, and from its colour at nrst sight looked likebrain matter; it could be entirely raised by the forceps, andon examination by the microscope was found to consist of a

great number of vessels, with much granular matter, and somefibrillated structure mixed therewitli. The softened braintexture consisted of granular matter, with great numbers ofoval, irregular nuclear cells, some wasted nerve tubes, andhere and there accumulations of star-shaped and caudate bodies,with dark margins, and having a calcareous appearance. On

section, the brain proved to be rather vascular, but of naturalconsistence generally; the ventricles were rather large, andcontained two or three drachms of clear fluid, but were notdistended. The arteries of the base of the brain were natural,and the other organs of the body did not offer any strikingabnormal condition.

____

KING’S COLLEGE HOSPITAL.

Cases of Epilepsy.(Under the care of Dr. TODD.)

BEING on the subject of epilepsy, we shall just refer, in afew words, to some curious cases which were treated by Dr.Todd some time ago, and which presented features of some in-terest.