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Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska Institutet Walking Spinal – selektiv unilateral spinal – Mini dos spinal

Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

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Page 1: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Spa vid dagkirurgi rdquonedan navelnrdquoen alternativ anestesiteknik

Jan JakobssonAnestesi amp Intensivvaringrd

Institutionen foumlr Fysiologi amp Farmakologi

Karolinska Institutet

Walking Spinal ndashselektiv unilateral spinal ndashMini dos spinal

Ambulatory anaesthesia

+ N itrous oxide

D esflurane

+ N itrous oxide

Sevoflurane

Inhaled anaesthesia

+ N itrous oxide

Propofol

In travenous anaesthesia

G eneral anaesthesia

M AC sedation

Local anaesthesia

SpinalW alking spinal

low dose B upi + fent

Am bulatory anaesthesia

plusmnFentanylAlfentanil

Remifentanil

Anestesi foumlr nedre extrimitetens ortopediska kirurgi

bull Houmlftproteskirurgi ndash Spa + LIAbull Knaumlproteskirurgi ndash Spa + LIAbull Akillessena - Spabull Korsband ndash Spabull Fotledskirurgi - Spabull Mellanfot - bull Framfot -

Lokalbedoumlvning

bull Marcain tungbull Marcain spinal

ndash Chirocaine 5 mgmlndash Narop 5 mgml

Spinalbedoumlvning

bull Marcain tung 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp till

exempel urologiska operationer och operationer i nedre extremiteterna som varar 2ndash3 timmar samt operationer i buken som varar 45ndash60 minuter

Indikation Dosml

Dos mg

Tillslagstidminuter (ca)

Durationtimmar (ca)

Urologisk kirurgi 15-3 ml 75-15 mg 5-8 min 2-3 timmar

Ingrepp i nedre extremiteter inklusive houmlftkirurgi

2-4 ml 10-20 mg 5-8 min 2-3 timmar

Bukkirurgi (inklusive kejsarsnitt)

2-4 ml 10-20 mg 5-8 min 45-60 min

Spinalbedoumlvning bull Marcain spinal 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp i

nedre extremiteter inklusive houmlftkirurgi som varar 3ndash4 timmar och daumlr en uttalad motorblockad behoumlvs

Indikation Dosml

Dos mg

Tillslagstidminuter

(ca)

Durationtimmar (ca)

Ingrepp iNedreExtremiteterInklusivehoumlftkirurgi

2-4 ml 10-20 mg 5-8 min 15-4 timmar

Spinalbedoumlvning

bull Narop 5 mgmlbull Indikationerbull Kirurgisk anestesi

spinalanestesi

Indikation Styrka mgml

Volym ml

Dos mg

Tillslag minuter

Duration timmar

Spinaladministrering foumlr kirurgi

5 mgml 3-4 ml 15-20 mg 1-5 min 2-6 tim

Spinalbedoumlvningbull Chirocaine 5 mgmlbull Indikationerbull Kirurgisk anestesi bull intratekal

DOSERINGSTABELL

Koncentrationmgml1

Dos Motorblockad

Kirurgisk anestesi

Intratekal 50 3 ml (15 mg)

Maringttlig till fullstaumlndig

Vilket medel aumlr baumlstbull Ropivacaine the S-isomer of the propyl homologue of

bupivacaine (Whiteside et al 2001) has approximately 50 of the potency of bupivacaine at equal doses when administered it (Gautier et al 1999 McDonald et al 1999)

bull Levobupivacaine is the S-enantiomer of bupivacaine with a lower degree of cardiotoxicity compared to racemic bupivacaine (Whiteside and Wildsmith 2001)

ndash Cardiotoxicity is not relevant with the bupivacaine doses (up to 20 mg) used in spinal anaesthesia

bull No difference was found between the spinal block after it bupivacaine or levobupivacaine (Alley et al 2002)

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 2: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Ambulatory anaesthesia

+ N itrous oxide

D esflurane

+ N itrous oxide

Sevoflurane

Inhaled anaesthesia

+ N itrous oxide

Propofol

In travenous anaesthesia

G eneral anaesthesia

M AC sedation

Local anaesthesia

SpinalW alking spinal

low dose B upi + fent

Am bulatory anaesthesia

plusmnFentanylAlfentanil

Remifentanil

Anestesi foumlr nedre extrimitetens ortopediska kirurgi

bull Houmlftproteskirurgi ndash Spa + LIAbull Knaumlproteskirurgi ndash Spa + LIAbull Akillessena - Spabull Korsband ndash Spabull Fotledskirurgi - Spabull Mellanfot - bull Framfot -

Lokalbedoumlvning

bull Marcain tungbull Marcain spinal

ndash Chirocaine 5 mgmlndash Narop 5 mgml

Spinalbedoumlvning

bull Marcain tung 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp till

exempel urologiska operationer och operationer i nedre extremiteterna som varar 2ndash3 timmar samt operationer i buken som varar 45ndash60 minuter

Indikation Dosml

Dos mg

Tillslagstidminuter (ca)

Durationtimmar (ca)

Urologisk kirurgi 15-3 ml 75-15 mg 5-8 min 2-3 timmar

Ingrepp i nedre extremiteter inklusive houmlftkirurgi

2-4 ml 10-20 mg 5-8 min 2-3 timmar

Bukkirurgi (inklusive kejsarsnitt)

2-4 ml 10-20 mg 5-8 min 45-60 min

Spinalbedoumlvning bull Marcain spinal 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp i

nedre extremiteter inklusive houmlftkirurgi som varar 3ndash4 timmar och daumlr en uttalad motorblockad behoumlvs

Indikation Dosml

Dos mg

Tillslagstidminuter

(ca)

Durationtimmar (ca)

Ingrepp iNedreExtremiteterInklusivehoumlftkirurgi

2-4 ml 10-20 mg 5-8 min 15-4 timmar

Spinalbedoumlvning

bull Narop 5 mgmlbull Indikationerbull Kirurgisk anestesi

spinalanestesi

Indikation Styrka mgml

Volym ml

Dos mg

Tillslag minuter

Duration timmar

Spinaladministrering foumlr kirurgi

5 mgml 3-4 ml 15-20 mg 1-5 min 2-6 tim

Spinalbedoumlvningbull Chirocaine 5 mgmlbull Indikationerbull Kirurgisk anestesi bull intratekal

DOSERINGSTABELL

Koncentrationmgml1

Dos Motorblockad

Kirurgisk anestesi

Intratekal 50 3 ml (15 mg)

Maringttlig till fullstaumlndig

Vilket medel aumlr baumlstbull Ropivacaine the S-isomer of the propyl homologue of

bupivacaine (Whiteside et al 2001) has approximately 50 of the potency of bupivacaine at equal doses when administered it (Gautier et al 1999 McDonald et al 1999)

bull Levobupivacaine is the S-enantiomer of bupivacaine with a lower degree of cardiotoxicity compared to racemic bupivacaine (Whiteside and Wildsmith 2001)

ndash Cardiotoxicity is not relevant with the bupivacaine doses (up to 20 mg) used in spinal anaesthesia

bull No difference was found between the spinal block after it bupivacaine or levobupivacaine (Alley et al 2002)

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 3: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Anestesi foumlr nedre extrimitetens ortopediska kirurgi

bull Houmlftproteskirurgi ndash Spa + LIAbull Knaumlproteskirurgi ndash Spa + LIAbull Akillessena - Spabull Korsband ndash Spabull Fotledskirurgi - Spabull Mellanfot - bull Framfot -

Lokalbedoumlvning

bull Marcain tungbull Marcain spinal

ndash Chirocaine 5 mgmlndash Narop 5 mgml

Spinalbedoumlvning

bull Marcain tung 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp till

exempel urologiska operationer och operationer i nedre extremiteterna som varar 2ndash3 timmar samt operationer i buken som varar 45ndash60 minuter

Indikation Dosml

Dos mg

Tillslagstidminuter (ca)

Durationtimmar (ca)

Urologisk kirurgi 15-3 ml 75-15 mg 5-8 min 2-3 timmar

Ingrepp i nedre extremiteter inklusive houmlftkirurgi

2-4 ml 10-20 mg 5-8 min 2-3 timmar

Bukkirurgi (inklusive kejsarsnitt)

2-4 ml 10-20 mg 5-8 min 45-60 min

Spinalbedoumlvning bull Marcain spinal 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp i

nedre extremiteter inklusive houmlftkirurgi som varar 3ndash4 timmar och daumlr en uttalad motorblockad behoumlvs

Indikation Dosml

Dos mg

Tillslagstidminuter

(ca)

Durationtimmar (ca)

Ingrepp iNedreExtremiteterInklusivehoumlftkirurgi

2-4 ml 10-20 mg 5-8 min 15-4 timmar

Spinalbedoumlvning

bull Narop 5 mgmlbull Indikationerbull Kirurgisk anestesi

spinalanestesi

Indikation Styrka mgml

Volym ml

Dos mg

Tillslag minuter

Duration timmar

Spinaladministrering foumlr kirurgi

5 mgml 3-4 ml 15-20 mg 1-5 min 2-6 tim

Spinalbedoumlvningbull Chirocaine 5 mgmlbull Indikationerbull Kirurgisk anestesi bull intratekal

DOSERINGSTABELL

Koncentrationmgml1

Dos Motorblockad

Kirurgisk anestesi

Intratekal 50 3 ml (15 mg)

Maringttlig till fullstaumlndig

Vilket medel aumlr baumlstbull Ropivacaine the S-isomer of the propyl homologue of

bupivacaine (Whiteside et al 2001) has approximately 50 of the potency of bupivacaine at equal doses when administered it (Gautier et al 1999 McDonald et al 1999)

bull Levobupivacaine is the S-enantiomer of bupivacaine with a lower degree of cardiotoxicity compared to racemic bupivacaine (Whiteside and Wildsmith 2001)

ndash Cardiotoxicity is not relevant with the bupivacaine doses (up to 20 mg) used in spinal anaesthesia

bull No difference was found between the spinal block after it bupivacaine or levobupivacaine (Alley et al 2002)

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 4: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Lokalbedoumlvning

bull Marcain tungbull Marcain spinal

ndash Chirocaine 5 mgmlndash Narop 5 mgml

Spinalbedoumlvning

bull Marcain tung 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp till

exempel urologiska operationer och operationer i nedre extremiteterna som varar 2ndash3 timmar samt operationer i buken som varar 45ndash60 minuter

Indikation Dosml

Dos mg

Tillslagstidminuter (ca)

Durationtimmar (ca)

Urologisk kirurgi 15-3 ml 75-15 mg 5-8 min 2-3 timmar

Ingrepp i nedre extremiteter inklusive houmlftkirurgi

2-4 ml 10-20 mg 5-8 min 2-3 timmar

Bukkirurgi (inklusive kejsarsnitt)

2-4 ml 10-20 mg 5-8 min 45-60 min

Spinalbedoumlvning bull Marcain spinal 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp i

nedre extremiteter inklusive houmlftkirurgi som varar 3ndash4 timmar och daumlr en uttalad motorblockad behoumlvs

Indikation Dosml

Dos mg

Tillslagstidminuter

(ca)

Durationtimmar (ca)

Ingrepp iNedreExtremiteterInklusivehoumlftkirurgi

2-4 ml 10-20 mg 5-8 min 15-4 timmar

Spinalbedoumlvning

bull Narop 5 mgmlbull Indikationerbull Kirurgisk anestesi

spinalanestesi

Indikation Styrka mgml

Volym ml

Dos mg

Tillslag minuter

Duration timmar

Spinaladministrering foumlr kirurgi

5 mgml 3-4 ml 15-20 mg 1-5 min 2-6 tim

Spinalbedoumlvningbull Chirocaine 5 mgmlbull Indikationerbull Kirurgisk anestesi bull intratekal

DOSERINGSTABELL

Koncentrationmgml1

Dos Motorblockad

Kirurgisk anestesi

Intratekal 50 3 ml (15 mg)

Maringttlig till fullstaumlndig

Vilket medel aumlr baumlstbull Ropivacaine the S-isomer of the propyl homologue of

bupivacaine (Whiteside et al 2001) has approximately 50 of the potency of bupivacaine at equal doses when administered it (Gautier et al 1999 McDonald et al 1999)

bull Levobupivacaine is the S-enantiomer of bupivacaine with a lower degree of cardiotoxicity compared to racemic bupivacaine (Whiteside and Wildsmith 2001)

ndash Cardiotoxicity is not relevant with the bupivacaine doses (up to 20 mg) used in spinal anaesthesia

bull No difference was found between the spinal block after it bupivacaine or levobupivacaine (Alley et al 2002)

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 5: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Spinalbedoumlvning

bull Marcain tung 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp till

exempel urologiska operationer och operationer i nedre extremiteterna som varar 2ndash3 timmar samt operationer i buken som varar 45ndash60 minuter

Indikation Dosml

Dos mg

Tillslagstidminuter (ca)

Durationtimmar (ca)

Urologisk kirurgi 15-3 ml 75-15 mg 5-8 min 2-3 timmar

Ingrepp i nedre extremiteter inklusive houmlftkirurgi

2-4 ml 10-20 mg 5-8 min 2-3 timmar

Bukkirurgi (inklusive kejsarsnitt)

2-4 ml 10-20 mg 5-8 min 45-60 min

Spinalbedoumlvning bull Marcain spinal 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp i

nedre extremiteter inklusive houmlftkirurgi som varar 3ndash4 timmar och daumlr en uttalad motorblockad behoumlvs

Indikation Dosml

Dos mg

Tillslagstidminuter

(ca)

Durationtimmar (ca)

Ingrepp iNedreExtremiteterInklusivehoumlftkirurgi

2-4 ml 10-20 mg 5-8 min 15-4 timmar

Spinalbedoumlvning

bull Narop 5 mgmlbull Indikationerbull Kirurgisk anestesi

spinalanestesi

Indikation Styrka mgml

Volym ml

Dos mg

Tillslag minuter

Duration timmar

Spinaladministrering foumlr kirurgi

5 mgml 3-4 ml 15-20 mg 1-5 min 2-6 tim

Spinalbedoumlvningbull Chirocaine 5 mgmlbull Indikationerbull Kirurgisk anestesi bull intratekal

DOSERINGSTABELL

Koncentrationmgml1

Dos Motorblockad

Kirurgisk anestesi

Intratekal 50 3 ml (15 mg)

Maringttlig till fullstaumlndig

Vilket medel aumlr baumlstbull Ropivacaine the S-isomer of the propyl homologue of

bupivacaine (Whiteside et al 2001) has approximately 50 of the potency of bupivacaine at equal doses when administered it (Gautier et al 1999 McDonald et al 1999)

bull Levobupivacaine is the S-enantiomer of bupivacaine with a lower degree of cardiotoxicity compared to racemic bupivacaine (Whiteside and Wildsmith 2001)

ndash Cardiotoxicity is not relevant with the bupivacaine doses (up to 20 mg) used in spinal anaesthesia

bull No difference was found between the spinal block after it bupivacaine or levobupivacaine (Alley et al 2002)

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 6: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Spinalbedoumlvning bull Marcain spinal 5 mgmlbull Indikationerbull Spinalanestesi vid kirurgiska ingrepp i

nedre extremiteter inklusive houmlftkirurgi som varar 3ndash4 timmar och daumlr en uttalad motorblockad behoumlvs

Indikation Dosml

Dos mg

Tillslagstidminuter

(ca)

Durationtimmar (ca)

Ingrepp iNedreExtremiteterInklusivehoumlftkirurgi

2-4 ml 10-20 mg 5-8 min 15-4 timmar

Spinalbedoumlvning

bull Narop 5 mgmlbull Indikationerbull Kirurgisk anestesi

spinalanestesi

Indikation Styrka mgml

Volym ml

Dos mg

Tillslag minuter

Duration timmar

Spinaladministrering foumlr kirurgi

5 mgml 3-4 ml 15-20 mg 1-5 min 2-6 tim

Spinalbedoumlvningbull Chirocaine 5 mgmlbull Indikationerbull Kirurgisk anestesi bull intratekal

DOSERINGSTABELL

Koncentrationmgml1

Dos Motorblockad

Kirurgisk anestesi

Intratekal 50 3 ml (15 mg)

Maringttlig till fullstaumlndig

Vilket medel aumlr baumlstbull Ropivacaine the S-isomer of the propyl homologue of

bupivacaine (Whiteside et al 2001) has approximately 50 of the potency of bupivacaine at equal doses when administered it (Gautier et al 1999 McDonald et al 1999)

bull Levobupivacaine is the S-enantiomer of bupivacaine with a lower degree of cardiotoxicity compared to racemic bupivacaine (Whiteside and Wildsmith 2001)

ndash Cardiotoxicity is not relevant with the bupivacaine doses (up to 20 mg) used in spinal anaesthesia

bull No difference was found between the spinal block after it bupivacaine or levobupivacaine (Alley et al 2002)

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 7: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Spinalbedoumlvning

bull Narop 5 mgmlbull Indikationerbull Kirurgisk anestesi

spinalanestesi

Indikation Styrka mgml

Volym ml

Dos mg

Tillslag minuter

Duration timmar

Spinaladministrering foumlr kirurgi

5 mgml 3-4 ml 15-20 mg 1-5 min 2-6 tim

Spinalbedoumlvningbull Chirocaine 5 mgmlbull Indikationerbull Kirurgisk anestesi bull intratekal

DOSERINGSTABELL

Koncentrationmgml1

Dos Motorblockad

Kirurgisk anestesi

Intratekal 50 3 ml (15 mg)

Maringttlig till fullstaumlndig

Vilket medel aumlr baumlstbull Ropivacaine the S-isomer of the propyl homologue of

bupivacaine (Whiteside et al 2001) has approximately 50 of the potency of bupivacaine at equal doses when administered it (Gautier et al 1999 McDonald et al 1999)

bull Levobupivacaine is the S-enantiomer of bupivacaine with a lower degree of cardiotoxicity compared to racemic bupivacaine (Whiteside and Wildsmith 2001)

ndash Cardiotoxicity is not relevant with the bupivacaine doses (up to 20 mg) used in spinal anaesthesia

bull No difference was found between the spinal block after it bupivacaine or levobupivacaine (Alley et al 2002)

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 8: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Spinalbedoumlvningbull Chirocaine 5 mgmlbull Indikationerbull Kirurgisk anestesi bull intratekal

DOSERINGSTABELL

Koncentrationmgml1

Dos Motorblockad

Kirurgisk anestesi

Intratekal 50 3 ml (15 mg)

Maringttlig till fullstaumlndig

Vilket medel aumlr baumlstbull Ropivacaine the S-isomer of the propyl homologue of

bupivacaine (Whiteside et al 2001) has approximately 50 of the potency of bupivacaine at equal doses when administered it (Gautier et al 1999 McDonald et al 1999)

bull Levobupivacaine is the S-enantiomer of bupivacaine with a lower degree of cardiotoxicity compared to racemic bupivacaine (Whiteside and Wildsmith 2001)

ndash Cardiotoxicity is not relevant with the bupivacaine doses (up to 20 mg) used in spinal anaesthesia

bull No difference was found between the spinal block after it bupivacaine or levobupivacaine (Alley et al 2002)

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 9: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Vilket medel aumlr baumlstbull Ropivacaine the S-isomer of the propyl homologue of

bupivacaine (Whiteside et al 2001) has approximately 50 of the potency of bupivacaine at equal doses when administered it (Gautier et al 1999 McDonald et al 1999)

bull Levobupivacaine is the S-enantiomer of bupivacaine with a lower degree of cardiotoxicity compared to racemic bupivacaine (Whiteside and Wildsmith 2001)

ndash Cardiotoxicity is not relevant with the bupivacaine doses (up to 20 mg) used in spinal anaesthesia

bull No difference was found between the spinal block after it bupivacaine or levobupivacaine (Alley et al 2002)

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 10: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Dos och tid till utskrivning

ndash In a dose-response study of hyperbaric bupivacaine (375 ndash 1125 mg) in volunteers each additional mg of bupivacaine increased the time to home readiness by 21 min (Liu et al 1996)

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 11: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Kontraindikation

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
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Page 12: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Allergi

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 13: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Systemtoxiska effekter

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 14: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Complications in regional anaesthesia

Moen V Dahlgren N Irestedt LAnesthesiology 2004 Oct101(4)950-9

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 15: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

CNSSpinal cord

Central Nervous System

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 16: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Spinalkanalen

Intratekalt Epiduralt

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 17: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Kroppslaumlgebull Sittandebull Liggandebull Horisontalt

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
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Page 18: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

PunktionsnivaringL3-L4L2-L3

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
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  • Slide 4
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Page 19: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Vad paringverkar hur spinalen sprider sig

bull Greene reported 25 factors that could affect the distribution of the local anaesthetic in the cerebrospinal fluid (Greene 1985) but not all of them have clinical relevance

bull These factors can be classified into 4 subgroups characteristics of the patient and of the CSF characteristics of the local anaesthetic agent and the injection technique used (Table 2)

bull Besides the drug dosage the position of the patient at the time of injection and thereafter together with the baricity of the anaesthetic are the most important factors affecting the level of spinal anaesthesia (Stienstra and Greene 1991 Connolly and Wildsmith 1998 Enk 1998)

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 20: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Lite kring faktorerna som paringverkar utbredning och aringterhaumlmtning

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 21: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Selektiv unilateral spinalbull The advantages of unilateral or selective versus

conventional SA are ndash better haemodynamic stability (Tanasichuk et al 1961 Pittoni

et al 1995 Vaghadia et al 1997 Fanelli et al 2000) ndash faster motor and sensory recovery (Vaghadia et al 1997

Vaghadia 1998 Fanelli et al 2000) ndash decreased risk of urinary retention (Ben-David et al 1996 Ben-

David et al 1997 Ben-David et al 2000 Kuusniemi et al 2000a Mulroy et al 2002)

ndash The patientsrsquo satisfaction with the unilateral techniques has been high too (Pittoni et al 1995 Kuusniemi et al 1997 Kuusniemi et al 2000a)

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 22: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

SSA

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 23: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

SSA

Administration

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 24: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

SSA

Kranialt SakraltHorisontalt

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 25: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

SSA

Kranialt Sakralt

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
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  • Slide 12
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Page 26: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Spinalanestesi mix bull rdquosingel shotrdquo

ndash Adrenalinndash Opioid

raquo Sufentaraquo fentanylraquo Morfinraquo kombinationer

ndash Alfa-2agonisterraquo Clonidin

ndash kateter

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 27: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Olika blandningar inte helt laumltt

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 28: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Men vad aumlr baumlst

bull Recently several studies with low-dose bupivacaine for ambulatory knee arthroscopy have been conducted with varying failure rates and time to home-readiness

bull Maringnga olika tekniker inte helt laumltttolkade resultat

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 29: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

METHODS bull One hundred healthy premedicated patients

randomly received conventional bilateral (n = 50) or unilateral (n = 50) spinal anesthesia with 8 mg hyperbaric bupivacaine 05

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 30: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group

on Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51RESULTS bull Three patients in each group were excluded due to

failed block bull Readiness for surgery required 13 min (5 - 25 min) with

bilateral and 16 min (15 - 30) with unilateral spinal block (P = 00005)

bull Sensory and motor blocks on the operated limb were T9 (T12 - T2) with a Bromage score 0123 02045 in the unilateral group and T7 (T12 - T1) with Bromage score 0123 41636 with bilateral block(P = 0026 and P = 0016 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 31: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull Vasopressor was required only in five bilateral patients (P = 002)

bull Two segment regression of sensory level and home discharge required 81+-25 min and 281+-83 min with bilateral block and 99+-28 min and 264+-95 min with unilateral block

bull (P = 0002 and P = 090 respectively)

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 32: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy Italian Study Group on

Unilateral Spinal AnesthesiaFanelli G Borghi B Casati A Bertini L Montebugnoli M Torri G

Can J Anaesth 2000 Aug47(8)746-51

bull CONCLUSION Seeking unilateral distribution of spinal anesthesia provided more profound and longer lasting block in the operated limb less cardiovascular effects and similar home discharge compared with bilateral spinal anesthesia with only a slight delay in preparation time

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 33: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6bull To evaluate the onset time success rate and recovery profile of

unilateral spinal anesthesia produced with 4 mg 6 mg and 8 mg of 05 hyperbaric bupivacaine

MEASUREMENTS AND MAIN RESULTS ndash The onset time of surgical block

bull 13 +- 5 minutes in Group 4 bull 10 +- 4 minutes in Group 6 (p = 0006) bull 9 +- 4 minutes in Group 8 (p = 0002)

ndash The maximum level of sensory block on the operative and nonoperative sides wasraquo T(10) (T(12)-T(6)) and (-L(2)) in Group 4 (p = 00005) raquo T(8) (T(12)-T(6)) and (-L(5)) in Group 6 (p = 00005) raquo T(7) (T(12)-T(5)) and (-T(10)) in Group 8 (p = 00005)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
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Page 34: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash A strictly unilateral sensory block was observed inbull 27 Group 4 patients (90) bull 28 Group 6 patients (93) bull 23 Group 8 patients (77) (p = 028)

ndash Complete unilateral motor block was observed inbull 29 Group 4 patients (97) bull 28 Group 6 patients (93) bull 28 Group 8 patients (93) (p = 080)

ndash No failed blocks were reported

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 35: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

ndash Complete regression of spinal anesthesia required

bull 71 +- 20 minutes in Group 4 (range 40 to 110 min) bull 82 +- 25 minutes in Group 6 (range 30 to 160 min) bull 97 +- 37 minutes in Group 8 (range 50 to 120 min)

raquo (p = 0003)

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 36: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Unilateral spinal block for outpatient knee

arthroscopy a dose-finding study Borghi B et al A J Clin Anesth 2003 Aug15(5)351-6

CONCLUSIONS Hyperbaric bupivacaine 4 mg injected slowly through pencil-point directional needles in patients who are maintained in the lateral decubitus position for 15 minutes provided a surgical block that was mostly restricted to the operative side and adequate to perform knee arthroscopy with a faster recovery profile than when a 6 mg or 8 mg dose was used

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 37: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

SSA

bull Bupivacainbull Chirocainbull Ropivacain

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
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Page 38: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg

Kallio H Snaumlll EV Kero MP Rosenberg PH Anesth Analg 2004 Sep99(3)713-7

This prospective randomized double-blinded study included 90 ambulatory lower-extremity surgery patients who received 2 mL ofndash ropivacaine 1 20 mgndash ropivacaine 075 15 mgndash bupivacaine 05 10 mg

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 39: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Aringterhaumlmtning

Kallio H et al

AampA 2004

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 40: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Kraft

Kallio H et al

AampA 2004

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 41: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower

limb surgerybull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for

ambulatory surgery of lower-extremities Hypothetically hyperbaric solution could improve and shorten the block

bull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery

of lower extremities They received intrathecally either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS bull All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5

min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION bull In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of

analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
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  • Slide 14
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  • Slide 16
  • Slide 17
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  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
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  • Slide 39
  • Slide 40
  • Slide 41
  • Slide 42
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  • Slide 44
  • Slide 45
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  • Slide 47
  • Slide 48
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  • Slide 56
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  • Slide 75
Page 42: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Comparison of hyperbaric and plain ropivacaine 15 mg in spinal anaesthesia for lower limb surgery

bull Br J Anaesth 2004 Nov93(5)664-9 Kallio H Snaumlll EV Tuomas CA Rosenberg PHbull BACKGROUND bull Previously plain ropivacaine 15 mg given intrathecally has been shown to be feasible for ambulatory surgery of lower-extremities

Hypothetically hyperbaric solution could improve and shorten the blockbull METHODS bull This prospective randomized double-blind study included 56 patients undergoing surgery of lower extremities They received intrathecally

either 15 ml of ropivacaine 10 mg ml(-1) and 05 ml of glucose 300 mg ml(-1) (HYP) or 2 ml of ropivacaine 75 mg ml(-1) (PL)

bull RESULTS All patients in Group HYP achieved T(10) dermatome analgesia but only 64 (1828) of Group PL T(10) analgesia was reached in 5 min (median range 5-20 min) in the HYP group vs 10 min (5-45 min) in the PL group (P=0022) and full motor block in 10 min (5-45 min) vs 20 min (5-60 min) (P=0003) respectively Group HYP had a longer duration of analgesia at T(10) 83 min (5-145 min) vs 33 min (0-140 min) (P=0004) Duration of sensory block from injection of the anesthetic to complete recovery was shorter in Group HYP than in Group PL 210 min (120-270 min) vs 270 min (210-360 min) (Plt0001) as was duration of motor block 120 min (5-150 min) vs 210 min (120-330 min) (Plt0001) Patients of Group HYP attained discharge criteria earlier than those of Group PL (P=0009)

bull CONCLUSION In comparison with the plain solution 15 mg of intrathecal hyperbaric ropivacaine produced a faster onset greater success rate of analgesia at the level of T(10) dermatome and faster recovery of the block

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
  • Slide 10
  • Slide 11
  • Slide 12
  • Slide 13
  • Slide 14
  • Slide 15
  • Slide 16
  • Slide 17
  • Slide 18
  • Slide 19
  • Slide 20
  • Slide 21
  • Slide 22
  • Slide 23
  • Slide 24
  • Slide 25
  • Slide 26
  • Slide 27
  • Slide 28
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Slide 38
  • Slide 39
  • Slide 40
  • Slide 41
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Slide 50
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • Slide 55
  • Slide 56
  • Slide 57
  • Slide 58
  • Slide 59
  • Slide 60
  • Slide 61
  • Slide 62
  • Slide 63
  • Slide 64
  • Slide 65
  • Slide 66
  • Slide 67
  • Slide 68
  • Slide 69
  • Slide 70
  • Slide 71
  • Slide 72
  • Slide 73
  • Slide 74
  • Slide 75
Page 43: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia

bull Br J Anaesth 2005 Jan94(1)107-11 Epub 2004 Oct 29 Fettes PD Hocking G Peterson MK Luck JF Wildsmith JA

bull BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine and may be of particular use in the day-case setting However there are few data comparing the actions of plain and hyperbaric solutions of this drug

bull METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to receive 3 ml ropivacaine 5 mg ml(-1) either in plain solution or with glucose 50 mg ml(-1) The extent and duration of sensory and motor block pulse rate blood pressure and time to mobilization were recorded

bull RESULTS Two patients (one per group) were withdrawn because of total block failure There were significant differences in median time to onset of sensory block at T10 (plain 10 min hyperbaric 5 min Plt001) median maximum extent (plain T8 hyperbaric T4 Plt005) and median duration of sensory block at T10 (plain 25 min hyperbaric 115 min Plt0001) However median times to complete regression of both sensory (270 vs 240 min Plt005) and motor (180 vs 120 min Plt0001) block were longer in the plain group Patients therefore mobilized sooner in the hyperbaric group (218 [n=16] vs 286 min [n=17] Plt001) All the hyperbaric blocks were adequate for surgery but three patients receiving plain ropivacaine required general anaesthesia

bull CONCLUSION Addition of glucose 50 mg ml(-1) to ropivacaine 5 mg ml(-1) increases the speed of onset block reliability duration of useful block for perineal surgery and speed of recovery Plain solutions are less reliable for surgery above a dermatomal level of L1

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
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  • Slide 75
Page 44: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

S tu dy flow

b u p iva ca in 4 m gL 3L4

G Ad e sflu ra ne

S tud y V

b u p iva ca in 4 m gL 2L3

b u p iva ca in 4 m gL 3L4

h e ad tilt

S tu dy IV

b u p iva ca in 4 m g

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gro d an se tron 4 m g iv

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

o n da n se tron 8 m g iv

S tu dy III

b u p iva ca in 3 m gfe n tan yl 10 m ic ro gr

S tu dy II

b u p iva ca in 4 m g b u p iva ca in 6 m g

S tud y I

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
  • Slide 10
  • Slide 11
  • Slide 12
  • Slide 13
  • Slide 14
  • Slide 15
  • Slide 16
  • Slide 17
  • Slide 18
  • Slide 19
  • Slide 20
  • Slide 21
  • Slide 22
  • Slide 23
  • Slide 24
  • Slide 25
  • Slide 26
  • Slide 27
  • Slide 28
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Slide 38
  • Slide 39
  • Slide 40
  • Slide 41
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Slide 50
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • Slide 55
  • Slide 56
  • Slide 57
  • Slide 58
  • Slide 59
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  • Slide 75
Page 45: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Erfarenheterna fraringn Finland

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
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Page 46: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Olika spinaler och tid till utskrivning

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
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Page 47: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Median upper level operative side

7 min 30 min EO 120 min

B3F IIIII

B4 II

B4 I

B6 I

Th7

Th8

Th9

Th10

Th11

Th12

L1

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
  • Slide 10
  • Slide 11
  • Slide 12
  • Slide 13
  • Slide 14
  • Slide 15
  • Slide 16
  • Slide 17
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  • Slide 21
  • Slide 22
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  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Slide 38
  • Slide 39
  • Slide 40
  • Slide 41
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Slide 50
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • Slide 55
  • Slide 56
  • Slide 57
  • Slide 58
  • Slide 59
  • Slide 60
  • Slide 61
  • Slide 62
  • Slide 63
  • Slide 64
  • Slide 65
  • Slide 66
  • Slide 67
  • Slide 68
  • Slide 69
  • Slide 70
  • Slide 71
  • Slide 72
  • Slide 73
  • Slide 74
  • Slide 75
Page 48: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Percent having S1 block

0

20

40

60

80

100

7 min EO 80 min 100 min 120 min 140 min 160 min

o

f th

e p

atie

nts

L23 L34T L34H

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
  • Slide 10
  • Slide 11
  • Slide 12
  • Slide 13
  • Slide 14
  • Slide 15
  • Slide 16
  • Slide 17
  • Slide 18
  • Slide 19
  • Slide 20
  • Slide 21
  • Slide 22
  • Slide 23
  • Slide 24
  • Slide 25
  • Slide 26
  • Slide 27
  • Slide 28
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Slide 38
  • Slide 39
  • Slide 40
  • Slide 41
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Slide 50
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • Slide 55
  • Slide 56
  • Slide 57
  • Slide 58
  • Slide 59
  • Slide 60
  • Slide 61
  • Slide 62
  • Slide 63
  • Slide 64
  • Slide 65
  • Slide 66
  • Slide 67
  • Slide 68
  • Slide 69
  • Slide 70
  • Slide 71
  • Slide 72
  • Slide 73
  • Slide 74
  • Slide 75
Page 49: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Recovery of motor function

0

20

40

60

80

100

80 min 120 min 160 min 200 min

Cu

mu

lati

ve

B4 I

B6 I

B3F II

B4 II

B3F III

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
  • Slide 10
  • Slide 11
  • Slide 12
  • Slide 13
  • Slide 14
  • Slide 15
  • Slide 16
  • Slide 17
  • Slide 18
  • Slide 19
  • Slide 20
  • Slide 21
  • Slide 22
  • Slide 23
  • Slide 24
  • Slide 25
  • Slide 26
  • Slide 27
  • Slide 28
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Slide 38
  • Slide 39
  • Slide 40
  • Slide 41
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Slide 50
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • Slide 55
  • Slide 56
  • Slide 57
  • Slide 58
  • Slide 59
  • Slide 60
  • Slide 61
  • Slide 62
  • Slide 63
  • Slide 64
  • Slide 65
  • Slide 66
  • Slide 67
  • Slide 68
  • Slide 69
  • Slide 70
  • Slide 71
  • Slide 72
  • Slide 73
  • Slide 74
  • Slide 75
Page 50: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Spinal anaesthetic technique

bull Low dosebull Low volumebull Low injection speedbull Lateral position for 10 minutesbull L 23bull 27 G Quincke needle

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
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  • Slide 35
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  • Slide 54
  • Slide 55
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  • Slide 60
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  • Slide 62
  • Slide 63
  • Slide 64
  • Slide 65
  • Slide 66
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  • Slide 68
  • Slide 69
  • Slide 70
  • Slide 71
  • Slide 72
  • Slide 73
  • Slide 74
  • Slide 75
Page 51: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures

sucess

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
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  • Slide 11
  • Slide 12
  • Slide 13
  • Slide 14
  • Slide 15
  • Slide 16
  • Slide 17
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  • Slide 20
  • Slide 21
  • Slide 22
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  • Slide 24
  • Slide 25
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  • Slide 28
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Slide 38
  • Slide 39
  • Slide 40
  • Slide 41
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Slide 50
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • Slide 55
  • Slide 56
  • Slide 57
  • Slide 58
  • Slide 59
  • Slide 60
  • Slide 61
  • Slide 62
  • Slide 63
  • Slide 64
  • Slide 65
  • Slide 66
  • Slide 67
  • Slide 68
  • Slide 69
  • Slide 70
  • Slide 71
  • Slide 72
  • Slide 73
  • Slide 74
  • Slide 75
Page 52: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Success rate

0

10

20

30

40

50

60

70

80

90

100

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4

failures

opioid suppl

sucess

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
  • Slide 10
  • Slide 11
  • Slide 12
  • Slide 13
  • Slide 14
  • Slide 15
  • Slide 16
  • Slide 17
  • Slide 18
  • Slide 19
  • Slide 20
  • Slide 21
  • Slide 22
  • Slide 23
  • Slide 24
  • Slide 25
  • Slide 26
  • Slide 27
  • Slide 28
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Slide 38
  • Slide 39
  • Slide 40
  • Slide 41
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Slide 50
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • Slide 55
  • Slide 56
  • Slide 57
  • Slide 58
  • Slide 59
  • Slide 60
  • Slide 61
  • Slide 62
  • Slide 63
  • Slide 64
  • Slide 65
  • Slide 66
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  • Slide 73
  • Slide 74
  • Slide 75
Page 53: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Success rate

0

2

4

6

8

10

12

14

No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

failures opioid suppl poor

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
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  • Slide 7
  • Slide 8
  • Slide 9
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  • Slide 36
  • Slide 37
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  • Slide 44
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  • Slide 73
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Page 54: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Quality aspects

0

5

10

15

20

25

30

35

40

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH spinal pain dysuria pruritus

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
  • Slide 10
  • Slide 11
  • Slide 12
  • Slide 13
  • Slide 14
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  • Slide 16
  • Slide 17
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  • Slide 19
  • Slide 20
  • Slide 21
  • Slide 22
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  • Slide 24
  • Slide 25
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  • Slide 28
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Slide 38
  • Slide 39
  • Slide 40
  • Slide 41
  • Slide 42
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  • Slide 44
  • Slide 45
  • Slide 46
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  • Slide 50
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  • Slide 55
  • Slide 56
  • Slide 57
  • Slide 58
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  • Slide 63
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  • Slide 68
  • Slide 69
  • Slide 70
  • Slide 71
  • Slide 72
  • Slide 73
  • Slide 74
  • Slide 75
Page 55: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Quality aspects

0

5

10

15

20

25

30

35

40No Pat

b4 b6 b3f b4 b3f b3f b3f b4 b4 b4 b4 des

PDPH back pain dysuria pruritus PONV

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
  • Slide 6
  • Slide 7
  • Slide 8
  • Slide 9
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  • Slide 75
Page 56: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with

desflurane for outpatient knee arthroscopybull Anesth Analg 2004 Dec99(6)1668-73 Korhonen AM Valanne JV Jokela RM Ravaska P Korttila KTbull Abstractbull In this randomized and controlled trial 64 adult ambulatory knee arthroscopy patients received either

selective spinal anesthesia (SSA) with 4 mg of hyperbaric bupivacaine or general anesthesia (GA) with desflurane We conducted the study to determine whether SSA with small-dose bupivacaine provides equal fast-tracking possibilities a shorter stay in the postanesthesia care unit and earlier discharge home compared with GA with desflurane Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group ndash No difference was seen in the fast-tracking possibilities or time in the

postanesthesia care unit between the groups ndash Home readiness was achieved after 114 (31-174) and 129 (28-245) min (NS)

in the SSA and GA groups respectively ndash In the hospital the pain scores were significantly (P lt 0001) lower in the SSA

group compared with the GA group and the need for postoperative opioids was significantly (P = 0008) larger after GA

ndash The incidence of postoperative nausea and vomiting was 0 versus 19 in the SSA and GA groups (P = 0024) respectively

bull We conclude that for outpatients undergoing knee arthroscopy SSA with hyperbaric bupivacaine provides equal recovery times with less frequent side effects compared with GA with desflurane

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 57: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Artroskopi av knaumlt

bull Locally applied anaesthesiabull Number of ports

ndash SURGERYbull Meniscus resectionbull Shavingbull rdquoother majorrdquo

bull Irrigating fluidbull Fluid pressurebull Tourniquet

ndash Time ndash Pressure

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 58: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Foumlrsoumlk till sammanfattning

bull Unilateral rdquoselektivrdquo walking spinal foumlr operation nedre extremitetenndash L3-4 rdquolaumlttrdquo

ndash saumlnkt huvudaumlnda vid knauml op

ndash 4 mg Marcain tung ndash Baumlttre kvalitet men mer klaringda med 10 microgr fentanyl

ndash Laringngsam injektionndash Beharingll sidolaumlge ca 10 minuter

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
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Page 59: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Men saring kom det studier fraringn Spainhellip

bull Group I received 5 mg (1 mL) levobupivacaine 05 (Chirocane 05 Abbott Laboratories Madrid Spain) with 10 g fentanyl (02 mL)

bull Group II received 4 mg (08 mL) levobupivacaine 05with 10 g fentanyl bull Group III received 3 mg (06 mL) levobupivacaine 05 with 10 g fentanyl bull All solutions were prepared to a total volume of 3 mL with sterile water bull The solutions had a specific gravity of 0999510 0998945 and 0998470

mgmL at 25degC respectively (Anton Paar Graz Austria)ndash Spinal anesthesia was performed by one of the authors who was not involved in further patient

evaluation

bull The spinal technique was performed in the sitting position with a midline approach at the L3-4 intervertebral space using a 27-gauge Whitacre spinal needle (Becton Dickinson Medical Systems Madrid Spain)

bull After sitting for 2 minutes patients were placed in the supine position with the back section of the surgical table elevated to 20deg to 30deg for 5 to 10 minutes

bull3 mg avbroumlts foumlr mycket failures

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

  • Slide 1
  • Slide 2
  • Slide 3
  • Slide 4
  • Slide 5
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Page 60: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

bull The patient was placed in the sitting position

bull Combined spinalndashepidural anesthesia (CSEA) was instituted in the sitting position with a midline approach at the L2ndashL3 level in all

bull subjects

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 61: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

bull Ropivacaine 05 5 mg (Naropin AstraZeneca USA) was mixed with 25 μg fentanyl and sterile water

bull The specific gravity of this mixture was 1002 as the specific gravity of cerebrospinal fluid is 1003ndash1008 at 378C this mixture would be hypobaric in this fluid

ndash Specific gravity was determined with a refractometer (American Optical Company Chicago IL USA) measured at 378C

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 62: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

bull Levobupivacaine 075 375 mg (Chirocaine Abbott Laboratories North Chicago IL USA) was mixed with 25 μg fentanyl and sterile water

bull the specific gravity of this mixture was 1001

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 63: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

bull Each of the solutions was diluted to a total volume of 3 ml with distilled water

bull The solution was injected over 150ndash180 s after free cerebrospinal fluid leakage was obtained through the needle

bull The tip of the needle was pointed in the cephalad direction during this process

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 64: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Spinal anesthesia mediates improved early function and pain relief following surgical repair of ankle

fracturesbull J Bone Joint Surg Am 2010 Feb92(2)368-74 Jordan C Davidovitch RI Walsh M Tejwani N Rosenberg A Egol KAbull bull BACKGROUND To our knowledge no study to date has compared the use of spinal and general anesthesia in patients

undergoing operative fixation of an unstable ankle fracture The purpose of this study was to assess the effects of anesthesia type on postoperative pain and function in a large cohort of patients

bull METHODS Between October 2000 and November 2006 501 patients who underwent surgical fixation of an unstable ankle fracture were followed prospectively Patients receiving spinal anesthesia were compared with a cohort who received general anesthesia All patients were evaluated at three six and twelve months postoperatively with use of standardized validated general and limb-specific outcome instruments Standard and multivariable analyses comparing outcomes at these intervals were performed

bull RESULTS Four hundred and sixty-six patients (93) who had been followed for a minimum of one year met the inclusion criteria

bull Compared with the general anesthesia group the spinal anesthesia group had a greater mean age (p = 0005) higher classification on the American Society of Anesthesiologists system (p = 003) and a greater number of patients with diabetes (p = 002)

bull There was no difference in sex distribution between the groups bull At three months patients who received spinal anesthesia had significantly better pain scores (p = 003) and total

scores on the American Orthopaedic Foot and Ankle Society outcome instrument (p = 002) At six months patients in the spinal anesthesia group continued to have better pain scores (p = 004) but there was no longer a difference in total scores (p = 006)

bull At twelve months no difference was detected between the groups in terms of functional or pain scores There was no difference in complication rates between the groups

bull CONCLUSIONS Patients who undergo fixation of an ankle fracture under spinal anesthesia seem to experience less pain and have better function in the early postoperative period We recommend that unless there is a specific contraindication patients should be offered spinal anesthesia when undergoing operative fixation of an ankle fracture

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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Page 65: Spa vid dagkirurgi ”nedan naveln” en alternativ anestesiteknik Jan Jakobsson Anestesi & Intensivvård Institutionen för Fysiologi & Farmakologi Karolinska

Svensk praxis ndash Knee arthroscopy routines and practice

bull Knee Surg Sports Traumatol Arthrosc 2010 Dec18(12)1656-60 Epub 2010 Sep 21bull Brattwall M Jacobson E Forssblad M Jakobsson Jbull Sourcebull Department of Anaesthesia Institute for Clinical Sciences at Sahlgrenska Academy Sahlgrenska University Hospital Moumllndal SE 431 80

Gothenburg Sweden methabrattwallvgregionsebull Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures thus consuming huge medical resources The aim of the

present questionnaire survey was to study knee arthroscopy routines and practicebull METHODS bull An electronic web-based survey including questions around pre- per- and postoperative routines for elective knee arthroscopy was send to all

orthopaedic units associated to the Swedish Arthroscopic Society (n = 60)bull RESULTS bull Responses covering 37 centres out of 60 (response rate 62) were returned Preoperative radiograph routines varied considerable between

centres conventional radiograph varied between 5 and 100 and preoperative MRI between 5 and 80 of patients bull General anaesthesia was the preferred intra-operative technique used in all centres (median 79 of

patients) local anaesthesia with or without light sedation was used in all 28 out of the 37 centres responding (median 10 of cases) and spinal anaesthesia was used in 15 centres (median 5 of cases)

bull Intra-articular local anaesthesia was provided in all but one of centres Perioperative administration of oral NSAIDs was common (31 out 37) 6 centres (all teaching hospitals) did not routinely give pre- or postoperative NSAID

bull Analgesic prescription was provided on a regular base in 18 (49) of centres an NSAID being the most commonly prescribed All but one centre provided written information and instruction at discharge Referral to physiotherapy prescribed sick leave and scheduled follow-up in the outpatient clinic diverged considerably

bull CONCLUSION bull Routines and practice associated to elective knee arthroscopy differed however no clear differences in practice were seen between teaching

centres general or local hospitals apart from a lower usage of NSAID for perioperative analgesia There is an obvious room for further standardisation in the routine handling of patients undergoing elective arthroscopy of the knee

bull helliptack

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