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Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas, Professor, Faculty of Medicine, UNSW, & Consultant Physician, Respiratory Medicine, Prince of Wales Hospital, Randwick 2031.

Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

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Page 1: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Sleeping Beauties: Obstructive sleep apnoea and other things that happen at

night

Paul S. Thomas, Professor, Faculty of Medicine,

UNSW,

&

Consultant Physician, Respiratory Medicine, Prince of Wales Hospital, Randwick 2031.

Page 2: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Outline

What is sleep apnoea? -how is it caused, how do we test for it and how to treat it Are there other events that can disrupt sleep? What is involved in testing for these disorders? What is the treatment?

Page 3: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Outline

Page 4: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Normal versus simple snoring versus obstructive

sleep apnoea

Page 5: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Symptoms & Assessment

» Daytime drowsiness

» Unrefreshing sleep

» Snoring

» Morning headache

» Complaints from bed partner or neighbours

– Alcohol

– Sedatives

– Nasal symptoms/ obstruction

– Tonsillitis

– Weight gain

Assessment

– Questionnaires:

Epworth Scale: In this situation what is your chance of falling asleep..?

STOP-BANG

» Berlin

Page 6: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Examination

– Male gender

– Large neck

– Obesity

– Small lower jaw

– Large tonsils

– Narrow throat

– Large tongue- unable to see tonsils

– Hypothyroidism

Page 7: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Investigations

– Sleep study

– Thyroid tests

Page 8: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Sleep study

Page 9: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Sleep study = Polysomnography

EEG/

Brain waves

Eye movements

Heart rhythm

Breaths

Chest and abdominal movements

Oxygen level

Page 10: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Normal sleep with episode of REM sleep

Page 11: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

OSA during an episode of REM sleep

Page 12: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Treatments for OSA

• Weight loss?

• Mild: nothing? position?

• Moderate & severe:

– 1. trial of ’CPAP’ (continuous positive airway

pressure)

– 2. Mandibular advancement splint

Page 13: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

CPAP

Page 14: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

How CPAP works

Page 15: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Mandibular advancement splints (MAS)

• MAS

– Need own dentition in upper and lower jaw

– Splints are moulded to fit over the teeth like

an upper and lower set of dentures or mouth

guard

– The lower jaw is incrementally moved

forwards: this brings the tongue forwards and

reduces the obstruction at the back of the

throat.

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Page 17: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,
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• Outcomes

– Perhaps 30-50% of those with moderate-severe OSA use a CPAP device regularly

– Devices have a SD card/upload facility for data analysis (compliance, hours, time used, humidifier setting, leak, estimated sleep apnoea)

Disadvantages: strapped up every night, not enough humidification, cumbersome, not for the claustrophobic

– Variable pressure devices (BiPAP, AutoSet) slightly more comfortable, about twice the price

– Fewer data for MAS

• Jaw joint ache, need to exercise the jaw in the morning

• More discreet

Page 20: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

• Other conditions

– Central sleep apnoea

– Restless legs

– Insomnia

– ‘Parasomnias’

– Catplexy

Page 21: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Central sleep apnoea

Page 22: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Central sleep apnoea

Page 23: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Central sleep apnoea

• Can be mixed with OSA

• More commonly associated with other diseases such as

stroke, heart failure (poor blood circulation), drugs

(opiates, anti-depressants), obesity – hypoventilation

• Treat the underlying cause

Page 24: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Restless legs!

Page 25: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Restless legs

Page 26: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Restless legs

Page 27: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,
Page 28: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Restless legs

• Usually the bed partner complains, not the patient

• Association with iron deficiency

• Familial tendency

• Treat- iron deficiency

• Some respond to anti-Parkinsonian drugs

Page 29: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Insomnia

• In brief, a large topic!

• Difficulty getting off to sleep

• Difficulty in getting back to sleep/ waking up too early

Page 30: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

Insomnia

• In brief, a large topic!

• Difficulty getting off to sleep

• Difficulty in getting back to sleep/ waking up too early

• Anxiety, drugs/caffeine, depression, need to pass urine, ex-shift workers

• Keep regular sleeping habits

• Do not read or watch TV in bed

• If you do not get off to sleep get up, do something boring and go back to bed after 20 -30 mins

Page 31: Sleeping Beauties: Obstructive sleep apnoea and other things … · 2019-11-13 · Sleeping Beauties: Obstructive sleep apnoea and other things that happen at night Paul S. Thomas,

• Are you still awake?!