Sintesis Protein Oleh Sel

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    Sintesis protein oleh sel

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    RF + GTP

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    Inhibitor of Protein Synthesis in Eukaryotes

    Abrin, Ricin Inhibits binding of aminoacyl t-RNA

    iphtheria to!in "ataly#es a reaction bet$een NA and E%& toyield an inacti'e factor( Inhibits translocation

    "hloramphenicol) Inhibits peptidyltransferase of mitochondrialribosomes( Is inacti'e against cytoplasmic

    ribosomes Puromycin) "auses premature chain termination by acting

    as an analogue of charged t-RNA

    %usidic acid) Inhibits translocation by altering an elongationfactor

    "yclohe!imide Inhibits peptidyltransferase Pactamycin Inhibits positioning of t-RNA*+eton the S

    ribosome

    Sho$domycin Inhibits formation of the E%&-tRNA*+et./Pcomple!

    Sparsomycin Inhibits translocation*also active on prokaryotic ribosomes

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    Antibiotics Inhibitor of Protein Synthesis in

    Prokaryotes

    /etracycline Inhibits positioning of t-RNA on A side in ribosome

    Strptomycin Inhibits formation of theE%&-tRNA*+eton the 0 Sribosome

    "hloramphenicol Inhibits peptidyltransferaseon ribosome

    Erythromycin Inhibits translocation

    Rifamycin Inhibits RNA synthesisbinding to RNA polymerase

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    1ambatan pembentukan protein

    Antibiotik menghambat pembentukan

    protein bakteri

    2irus mengganggu NA atau RNA