-
7/24/2019 Sintesis Protein Oleh Sel
1/12
Sintesis protein oleh sel
-
7/24/2019 Sintesis Protein Oleh Sel
2/12
-
7/24/2019 Sintesis Protein Oleh Sel
3/12
-
7/24/2019 Sintesis Protein Oleh Sel
4/12
-
7/24/2019 Sintesis Protein Oleh Sel
5/12
-
7/24/2019 Sintesis Protein Oleh Sel
6/12
-
7/24/2019 Sintesis Protein Oleh Sel
7/12
-
7/24/2019 Sintesis Protein Oleh Sel
8/12
RF + GTP
-
7/24/2019 Sintesis Protein Oleh Sel
9/12
-
7/24/2019 Sintesis Protein Oleh Sel
10/12
Inhibitor of Protein Synthesis in Eukaryotes
Abrin, Ricin Inhibits binding of aminoacyl t-RNA
iphtheria to!in "ataly#es a reaction bet$een NA and E%&
toyield an inacti'e factor( Inhibits translocation
"hloramphenicol) Inhibits peptidyltransferase of
mitochondrialribosomes( Is inacti'e against cytoplasmic
ribosomes Puromycin) "auses premature chain termination by
acting
as an analogue of charged t-RNA
%usidic acid) Inhibits translocation by altering an
elongationfactor
"yclohe!imide Inhibits peptidyltransferase Pactamycin Inhibits
positioning of t-RNA*+eton the S
ribosome
Sho$domycin Inhibits formation of the
E%&-tRNA*+et./Pcomple!
Sparsomycin Inhibits translocation*also active on prokaryotic
ribosomes
-
7/24/2019 Sintesis Protein Oleh Sel
11/12
Antibiotics Inhibitor of Protein Synthesis in
Prokaryotes
/etracycline Inhibits positioning of t-RNA on A side in
ribosome
Strptomycin Inhibits formation of theE%&-tRNA*+eton the 0
Sribosome
"hloramphenicol Inhibits peptidyltransferaseon ribosome
Erythromycin Inhibits translocation
Rifamycin Inhibits RNA synthesisbinding to RNA polymerase
-
7/24/2019 Sintesis Protein Oleh Sel
12/12
1ambatan pembentukan protein
Antibiotik menghambat pembentukan
protein bakteri
2irus mengganggu NA atau RNA
