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Dr.E.Manivannan

Lecturer School of Pharmacy Devi Ahilya Vishwavidyalaya Indore-452017 E-mail: drmanislab@gmail.com Mobile No.: 7509114754

(A) Educational Qualification

2005-2010 Ph.D. Doctoral Research at School of Pharmacy, Devi

Ahilya Vishwavidyalaya, Indore.

2000-2002 M.Pharm. specialization in Medicinal and Pharmaceutical

Chemistry from Shri. G.S. Institute of Technology and

Science, Indore and Rajiv Gandhi Proudyogiki

vishwavidyalaya, Bhopal.

1996-2000 B.Pharm. from The Tamil Nadu Dr.M.G.R Medical

University, Chennai, Tamil Nadu.

(B) Teaching Experience

2006-Todate Lecturer in School of Pharmacy, Devi Ahilya

Vishwavidyalaya, Indore.

(C) Research Experience

2011-2012 Post-Doctoral Research Fellowship cum Visiting Senior

Scientist (Academy of Finland) in University of Jyvaskyla,

Finland. (On Leave Dec-2011 to Dec 2012)

2003-2006 Junior and Senior Research Fellow (JRF & SRF),

University Grants Commission at School of Pharmacy,

Devi Ahilya Vishwavidyalaya, Indore.

2002-2003 Project Assistant in Bio-Organic Chemistry Laboratory,

National Institute of Immunology, New Delhi.

(D) Fellowships and Awards

1. “Post-Doctoral Research cum Visiting Scientist” at University of Jyvaskyla,

Finland funded by Academy of Finland (2011-12).

2. Travel Grant Award from “Miptec-2012” conference secretariat (2012),

Basel, Switzerland.

3. “AICTE-CAYT” award from All India Council for Technical Education, New

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Delhi (2008).

4. Junior Research Fellowship (JRF) and Senior Research Fellowship (SRF)

from University Grants Commission (UGC), New Delhi (2003-2006).

5. PG-Scholarship (M.Pharm) from All India Council for Technical Education

(AICTE), New Delhi.

6. Indo-Kare foundation scholarship for M.Pharm Thesis, Indo-Kare

foundation, Mumbai.

(E) Membership in Professional Bodies at National Level

1. Life Member of Association of Pharmacy Teachers of India (APTI)

2. Life Member of Indian Pharmacological Society (IPS)

(F) Editorial Boards Member

1. Editorial board member in ISRN Pharmaceutics Journal, Hindawi Publishers.

2. Technical Editor in American Journal of Drug Design and Development, Sci-

Alert.

(G) Participation and Presentation in International Conferences held Abroad

1. “Miptec-2009”- a leading European Drug Discovery Symposium held at Basel,

Switzerland.

2. “Euro-QSAR-2012” held at Vienna University, Austria.

3. “Miptec-2012”- a leading European Drug Discovery Symposium held at Basel,

Switzerland.

(H) List of Publications:

1. N. S. Hari Narayana Moorthy, C. Karthikeyan, E. Manivannan, P. Trivedi, Analysis of surface area features of structurally diverse molecules for Bcr/Abl kinase inhibitory activity and antiproliferative activity, Med Chem Res., 2013, DOI 10.1007/s00044-013-0852-5. (Print ISSN No. 1054-2523, ISSN No. 1554-8120 (Online), Impact Factor: 1.612).

2. N.S. Hari Narayana Moorthy, E. Manivannan, C. Karthikeyan and Piyush Trivedi , 6H-Indolo[2,3-b]Quinoxalines: DNA and Protein Interacting Scaffold for Pharmacological Activities, Mini-Reviews in Medicinal Chemistry, Volume 13, 14 Issues, 2013, Pp: 1415 – 1420. ISSN: 1389-5575 (Print), ISSN: 1875-5607 (Online), Impact Factor: 2.865.

3. Manivannan, E and N.S. Hari Narayana Moorthy, QSAR Analysis and Pharmacophore Mapping of Catecholic Flavonoids for Telomerase Inhibitory

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Activity, Lat. Am. J. Pharm. 32 (6): 802-8 (2013) (ISSN No. 0326-2383, Impact Factor: 0.244).

4. Manivannan, E., Chaturvedi, S.C., Analogue-based design, synthesis and docking of non-steroidal anti-inflammatory agents. Part 2: Methyl sulfanyl/methyl sulfonyl substituted 2,3-diaryl-2,3-dihydro-1H-quinazolin-4-ones, 2012, Bioorganic and Medicinal Chemistry , 20 (24) , pp. 7119-7127.

5. Manivannan, E., Moorthy, N.S.H.N., Structurally modified celecoxib analogues for selective COX-2 inhibition: A classical hansch QSAR approach, 2012, Latin American Journal of Pharmacy 31 (4) , pp. 561-566.

6. Parmar, H.S., Jain, P., Chauhan, D.S., Bhinchar, M.K., Munjal, V., Yusuf, M.,Choube, K., Manivannan, E., Kumar, A., DPP-IV inhibitory potential of naringin: An in silico, in vitro and in vivo study, 2012, Diabetes Research and Clinical Practice 97 (1) , pp. 105-111.

7. Sharma, R., Yadav, R., Manivannan, E., Study of effect of Stevia rebaudiana bertoni on oxidative stress in type-2 diabetic rat models, 2012, Biomedicine and Aging Pathology 2 (3) , pp. 126-131.

8. Manivannan, E., Chaturvedi, S.C., Analogue-based design, synthesis and molecular docking analysis of 2,3-diaryl quinazolinones as non-ulcerogenic anti-inflammatory agents, 2011, Bioorganic and Medicinal Chemistry 19 (15) , pp. 4520-4528.

9. Manivannan, E., Chaturvedi, S.C., QSAR investigations on benzylideneamino and phenyliminomethyl scaffolds for selective COX-2 inhibition: A Hansch approach, 2009, Medicinal Chemistry 5 (5) , pp. 440-445

10. Manivannan, E., Chaturvedi, S.C., QSAR analysis of centrally fused 1,5-diaryl pyrazoles for cyclooxygenase inhibition using MOE-Qua-SAR descriptors, 2009, Medicinal Chemistry Research 18 (5) , pp. 396-405.

11. Manivannan, E. Prasanna, S., First QSAR report on FSH receptor antagonistic activity: Quantitative investigations on physico-chemical and structural features among 6-amino-4-phenyltetrahydroquinoline derivatives, 2005, Bioorganic and Medicinal Chemistry Letters 15 (20) , pp. 4496-4501.

12. Prasanna, S., Manivannan, E., Chaturvedi, S.C., Quantitative structure-activity relationship analysis of 2,3-diaryl indoles as selective cyclooxygenase-2 inhibitors, 2005, Journal of Enzyme Inhibition and Medicinal Chemistry 20 (5) , pp. 455-461.

13. Prasanna, S., Manivannan, E., Chaturvedi, S.C., QSAR analyses of conformationally restricted 1,5-diaryl pyrazoles as selective COX-2 inhibitors: Application of connection table representation of ligands, 2005, Bioorganic and Medicinal Chemistry Letters 15 (8) , pp. 2097-2102.

14. Prasanna, S., Manivannan, E., Chaturvedi, S.C. Quantitative structure-activity relationship studies of cyclooxygenase inhibitors: A comprehensive analysis, 2005, Drug Development Research 64 (4) , pp. 220-231

15. Prasanna, S., Manivannan, E., Chaturvedi, S.C., QSAR studies on structurally similar 2-(4-methanesulfonylphenyl)pyran-4- ones as selective COX-2 inhibitors: A Hansch approach, 2005, Bioorganic and Medicinal Chemistry Letters 15 (2) , pp. 313-320.

16. Prasanna, S., Manivannan, E., Chaturvedi, S.C., QSAR analysis of 2,3-diaryl benzopyrans/pyrans as selective COX-2 inhibitors based on semiempirical AM1 calculations, 2004, QSAR and Combinatorial Science 23 (8) , pp. 621-628.

17. Prasanna, S., Manivannan, E., Chaturvedi, S.C., QSAR analysis of 2,2-dimethyl-4,5-diarylfuran-3(2H)-ones as selective cyclooxygenase-2 inhibitors, 2004, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry 43 (10) , pp. 2249-2253.

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18. Prasanna, S., Manivannan, E., Chaturvedi, S.C., Quantitative structure-activity relationship analysis of a series of 2,3-diaryl benzopyran analogues as novel selective cyclooxygenase-2 inhibitors, 2004, Bioorganic and Medicinal Chemistry Letters 14 (15) , pp. 4005-4011.

19. Manivannan, E., Prasanna, S., Chaturvedi, S.C., Rationalization of physico-chemical properties of 5, 6-diarylthiazolo [3,2-b]-1, 2, 4-triazoles towards cyclooxygenase-2 (COX-2) inhibition: A QSAR approach, 2004, Indian Journal of Biochemistry and Biophysics 41 (4) , pp. 179-183.

20. Prasanna, S., Manivannan, E., Chaturvedi, S.C., QSAR analysis of some fused pyrazoles as selective cyclooxygenase-2 inhibitors: A hansch approach, 2004, Archiv der Pharmazie 337 (8), pp. 440-444.

List of Invited lectures/Talks:

1. Delivered two invited lectures/Talk (Basic principles and methodologies of 2D and 3D-QSAR and applications of 2D, 3D-QSAR in drug discovery research) at DBT, Govt of India sponsored National workshop on “Computational Biology & Molecular dynamics-2011” organized by Bioinformatics Sub center, School of Biotechnology, DAVV, Indore.

List of Conference Presentations:

1. E. Manivannan and Ram A Vishwakarma., “Synthesis of Galactofuranose containing Glycan core of Lipophosphoglycan of Leishmania donovani Parasite” abstracted in Medicinal Chemistry Research., 2003, 12, 4/5, 276-277. International symposium “current trends in drug discovery-2004” CDRI, Lucknow (poster presentation).

2. E. Manivannan, C.S. Reddy and S.C Chaturvedi., “2D-QSAR analysis and catalyst based pharmacophore mapping of a series of 2-(4-methane sulphonyl phenyl) pyran-4-ones for selective COX-2 inhibition” abstracted in Medicinal Chemistry Research., 2007, 15, 1/6, 198-199. International symposium “current trends in drug discovery-2007” CDRI, Lucknow (poster presentation).

3. E. Manivannan, N. Rakeshiya, K.M. Singh, G.P. Mishra, R.K.Sharma, R.Sharma and S.C.Chaturvedi, Synthesis and evaluation of 3-(3-benzyloxy-phenyl)-1-(phenyl)- propen-1-ones as non-ulcerogenic anti-inflammatory compounds, 59th Indian pharmaceutical congress, Varanasi, 2007 (poster presentation).

4. D. Panigrahi, Y.Prasad, E.Manivannan, R.Sharma and S.C.Chaturvedi, synthesis and biological evaluation of 1,3,4-thiadiazole derivatives as anti-depressant, anxiolytics and anticonvulsant agents, 59th Indian pharmaceutical congress Varanasi, 2007 (poster presentation).

5. E.Manivannan, G.Mishra, and S.C. Chaturvedi, Design and Synthesis of 3-(3-benzyloxy-phenyl)-1-(phenyl)-propen-1-one derivative: Anti-inflammatory, Analgesic and GIT safety Assessment in poster session, IPA conference 2008, Indore. (poster presentation).

6. Elangovan Manivannan and S.C.Chaturvedi, Analogue-based design and synthesis of methylsulfonyl pharmacophore substituted 2,3 dioaryl quinazolinones as non ulcerogenic anti-inflammatory compounds, 12th MipTec conference-the leading European vent for drug discovery, congress Center, Basel, Switzerland, 2009. (poster presentation).

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7. Elangovan Manivannan and S.C.Chaturvedi, Design and Synthesis Of 2, 3-Diaryl Quinazolinones As Gastric Safe Anti-Inflammatory Compounds, abstracted in Medicinal Chemistry Research., 2010. International symposium “current trends in drug discovery- 2010” CDRI, Lucknow (poster presentation).

8. B. Gavande, E. Manivannan, R.K. Mehta and S.C. Chaturvedi, Evaluation of wound healing activity of methanol extract of Annona reticulate l (annonaceae) leaves, abstracted in Medicinal Chemistry Research., 2010. International symposium “current trends in drug discovery-2010” CDRI, Lucknow (poster presentation).

9. E.Manivannan, N.S.H.N. Moorthy, S.C.Chaturvedi. Comparative QSAR modeling of sulfonated quinazolinones and dihydroquinazolinones for its anti-inflammatory action, Euro-QSAR symposium-2012, Vienna University, Vienna, Austria. (poster presentation).

10. Elangovan Manivannan, Sanna Ninevehmas, O.T.Pentikainen. Development of reliable and efficient virtual screening strategy for the identification of selective estrogen receptor alpha modulators Miptec-2012: drug discovery symposium held at Basel, Switzerland.

11. E.Manivannan, R.Sharma, N.Shinde, Design, synthesis and antimicrobial evaluation of guanidine functionalized chalcones Shodh-samagam, BM College, Indore, India. (poster presentation).